Effect of multipotent mesenchymal stroma cells (MSC) on acute myeloid leukemia (AML) cells in vitro and in vivo (Englisch)

in Experimental hematology ; 43 ; S94
Experimental hematology
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343
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346
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599
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Skoda, Radek C. / Duek, Adrian / Grisouard, Jean | 2015
609
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625
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Durinck, Kaat / Goossens, Steven / Peirs, Sofie / Wallaert, Annelynn / Van Loocke, Wouter / Matthijssens, Filip / Pieters, Tim / Milani, Gloria / Lammens, Tim / Rondou, Pieter et al. | 2015
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654
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661
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685
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698
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821
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Blobel, Gerd A. / Bodine, David / Brand, Marjorie / Crispino, John / de Bruijn, Marella F.T.R. / Nathan, David / Papayannopoulou, Thalia / Porcher, Catherine / Strouboulis, John / Zon, Len et al. | 2015
838
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Flynn, Rowan / Grundmann, Alexander / Renz, Peter / Hänseler, Walther / James, William S. / Cowley, Sally A. / Moore, Michael D. | 2015
849
Targeted gene correction of RUNX1 in induced pluripotent stem cells derived from familial platelet disorder with propensity to myeloid malignancy restores normal megakaryopoiesis
Iizuka, Hiromitsu / Kagoya, Yuki / Kataoka, Keisuke / Yoshimi, Akihide / Miyauchi, Masashi / Taoka, Kazuki / Kumano, Keiki / Yamamoto, Takashi / Hotta, Akitsu / Arai, Shunya et al. | 2015
858
MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia
Gentner, Bernhard / Pochert, Nicole / Rouhi, Arefeh / Boccalatte, Francesco / Plati, Tiziana / Berg, Tobias / Sun, Su Ming / Mah, Sarah M. / Mirkovic-Hösle, Milijana / Ruschmann, Jens et al. | 2015
869
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Mannelli, Francesco / Ponziani, Vanessa / Bonetti, Maria Ida / Bencini, Sara / Cutini, Ilaria / Gianfaldoni, Giacomo / Scappini, Barbara / Pancani, Fabiana / Rondelli, Tommaso / Benelli, Matteo et al. | 2015
880
Expression of the ETS transcription factor GABPα is positively correlated to the BCR-ABL1/ABL1 ratio in CML patients and affects imatinib sensitivity in vitro
Manukjan, Georgi / Ripperger, Tim / Santer, Laura / von Neuhoff, Nils / Ganser, Arnold / Schambach, Axel / Schlegelberger, Brigitte / Steinemann, Doris | 2015
891
Microfluidic assessment of functional culture-derived platelets in human thrombi under flow
Kamat, Viraj / Muthard, Ryan W. / Li, Ruizhi / Diamond, Scott L. | 2015
901
Improved hematopoietic differentiation of primate embryonic stem cells by inhibition of the PI3K-AKT pathway under defined conditions
Nii, Takenobu / Marumoto, Tomotoshi / Kohara, Hiroshi / Yamaguchi, Saori / Kawano, Hirotaka / Sasaki, Erika / Kametani, Yoshie / Tani, Kenzaburo | 2015
912
Comparative long-term effects of interferon α and hydroxyurea on human hematopoietic progenitor cells
King, Katherine Y. / Matatall, Katie A. / Shen, Ching-Chieh / Goodell, Margaret A. / Swierczek, Sabina I. / Prchal, Josef T. | 2015
921
HLA haploidentical peripheral blood stem cell transplantation using reduced dose of posttransplantation cyclophosphamide for poor-prognosis or refractory leukemia and myelodysplastic syndrome
Nakamae, Hirohisa / Koh, Hideo / Katayama, Takako / Nishimoto, Mitsutaka / Hayashi, Yoshiki / Nakashima, Yasuhiro / Nakane, Takahiko / Nakamae, Mika / Hirose, Asao / Hino, Masayuki | 2015
930
Inactivation of Eed impedes MLL-AF9–mediated leukemogenesis through Cdkn2a-dependent and Cdkn2a-independent mechanisms in a murine model
Danis, Etienne / Yamauchi, Taylor / Echanique, Kristen / Haladyna, Jessica / Kalkur, Roshni / Riedel, Simone / Zhu, Nan / Xie, Huafeng / Bernt, Kathrin M. / Orkin, Stuart H. et al. | 2015
936
Disease dynamics in patients with acute myeloid leukemia: New biomarkers
Tzoran, Inna / Rebibo-Sabbah, Annie / Brenner, Benjamin / Aharon, Anat | 2015
944
A new ATL xenograft model and evaluation of pyrrolidine dithiocarbamate as a potential ATL therapeutic agent
Nakamura, Daisuke / Yoshimitsu, Makoto / Kuroki, Ayako / Hachiman, Miho / Kamada, Yuhei / Ezinne, Chibueze C. / Arai, Akihiko / Inoue, Hirosaka / Hamada, Heiichirou / Hayashida, Maiko et al. | 2015
951
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Fujita, Natsuko / Ichii, Michiko / Maeda, Tetsuo / Saitoh, Norimitsu / Yokota, Takafumi / Yamawaki, Kengo / Kakitani, Makoto / Tomizuka, Kazuma / Oritani, Kenji / Kanakura, Yuzuru | 2015
974
The tissue inhibitor of metalloproteinases 1 increases the clonogenic efficiency of human hematopoietic progenitor cells through CD63/PI3K/Akt signaling
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989
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993
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995
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1031
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1047
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1062
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1072
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A3
Contents
| 2015
e1
ISEH Annual Meeting Late Breaking Abstracts
| 2015
e11
ISEH Annual Meeting Abstract Changes
| 2015
S21
Reprint to: In memoriam: Donald Metcalf (1929-2014) – A historical perspective of his contributions to hematology
Nicola, Nicos A. / Alexander, Warren S. / Hilton, Douglas J. / Ng, Ashley P. | 2015
S107
Author Index
| 2015
Asymmetric cell division of hematopoietic stem cells
Loeffler, Dirk / Schroeder, Timm | 2015
Editorial Board
| 2015
Declined presentation inflammatory modulation of hematopoietic stromal niche cells by TNF-α leads to rapid mobilization of hematopoietic stem/progenitor cells (HSPC) and neutrophils
Park, Shin-Young / Anna Han, Eun Young / Jung, Yookyung / Lin, Charles P. / Silberstein, Leslie E. | 2015
Declined presentation Human platelet antigen genotype : effect on aspirinated platelets in patients with essential thrombocythemia
Cacciola, Rossella / Cacciola, Elio Gentilini / Cipolla, Antonino / Torre, Maria / Cacciola, Emma | 2015
CD11B+CX3CR1+ cells play a determining role in reparative angiogenesis after ischemic injury
Kim, Jeong-A / Kwak, Jae-Yong / Noh, Kyoungmi / Lee, Joon | 2015
A stromal organiser cell that directs neonatal spleen regeneration
Tan, Jon / Watanabe, Takeshi | 2015
Hematopoietic stem cell aging in humans associates with functional impairments and an intrinsic megakaryocytic/erythroid bias
Rundberg Nilsson, Alexandra J. / Bryder, David / Pronk, Cornelis J. | 2015
Down-regulation of NDRG2 plays an important role in ATLL leukemogenesis via the PTEN-mediated PI3K/AKT signaling pathway
Nakahata, Shingo / Ichikawa, Tomonaga / Yusuke, Saito / Arai, Yasuhito / Taki, Tomohiko / Taniwaki, Masafumi / Morishita, Kazuhiro | 2015
The clinical impact of both point mutated and alternatively spliced BCR-ABL in CML patients: result of highly-sensitive, deep sequencing study
Yuda, Junichiro / Miyamoto, Toshihiro / Odawara, Jun / Ohkawa, Yasuyuki / Akashi, Koichi | 2015
Defect in pre-ribosomal RNA processing is involved in myeloid leukemogenesis
Matsui, Hirotaka / Kanai, Akinori / Nagamachi, Akiko / Okuno, Moe / Inaba, Toshiya | 2015
Unipotent megakaryopoietic pathway bridging hematopoietic stem cells and mature megakaryocytes
Nishikii, Hidekazu / Umemoto, Terumasa / Goltsev, Yury / Matsuzaki, Yu / Yamato, Masayuki / Nolan, Garry / Negrin, Robert / Chiba, Shigeru | 2015
CD97 expression influences migration and adhesion of FLT3-ITD positive acute myeloid leukemia cells and modulates the bone marrow stromal microenvironment
Wobus, Manja / Oelschlägel, Uta / Ortlepp, Claudia / Jacobi, Angela / Bornhäuser, Martin | 2015
RNAi screen identifies cytohesin1 as a mediator of adhesion in human hematopoietic stem/progenitor cells
Rak, Justyna M. / Foster, Katie / Potrzebowska, Katarzyna / Talkhoncheh, Mehrnaz Safaee / Komorowska, Karolina / Törngren, Therese / Kvist, Anders / Svensson, Lena / Bonnet, Dominique / Larsson, Jonas | 2015
Effect of multipotent mesenchymal stroma cells (MSC) on acute myeloid leukemia (AML) cells in vitro and in vivo
Schelker, Roland C. / Müller, Gunnar / Hart, Christina / Klatt, Sabine / Herr, Wolfgang / Grassinger, Jochen | 2015
Activated KRAS enhances extramedullar engraftment and impairs clonogenic potential of MLLAF4-expressing cord blood CD34+ HSPCs but is not sufficient to initiate leukemia
Prieto, C. / Stam, Ronald / Ballerini, P. / Camos, M. / Marschalek, R. / Bursen, A. / Bueno, Clara / Menéndez, Pablo | 2015
Redefining the human blood progenitor hierarchy across development
Zandi, Sasan / Notta, Faiyaz / Takayama, Naoya / Dobson, Stephanie / Gan, Olga / Kaufmann, Kerstin B. / McLeod, Jessica / Dick, John E. | 2015
FACS-segregated c-kithigh and c-kitlow cells in the murine hematopoietic stem cell compartment are functionally distinct
Sasaki, Yutaka / Matsuoka, Yoshikazu / Nakatsuka, Ryusuke / Sumide, Keisuke / Kawamura, Hiroshi / Fujioka, Tatsuya / Sonoda, Yoshiaki | 2015
Declined presentation defining hematopoietic stem cell subtypes and their role in hematopoietic regeneration and ageing
Grover, Amit / Sanjuan-Pla, Alejandra / de Teixeira Carelha, Joana / Thongjuea, Supat / Jacobsen, Sten Eirik W. / Nerlov, Claus | 2015
Prospective isolation of human hematopoietic stem cell-supportive mesenchymal stem/stromal cells from human bone marrow
Matsuoka, Yoshikazu / Sumide, Keisuke / Kawamura, Hiroshi / Nakatsuka, Ryusuke / Fujioka, Tatsuya / Sasaki, Yutaka / Sonoda, Yoshiaki | 2015
EZH2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an EZH1-depenedent manner
Mochizuki-Kashio, Makiko / Sashida, Goro / Aoyama, Kazumasa / Wang, Changshan / Tomioka, Takahisa / Oshima, Motohiko / Iwama, Atsushi | 2015
Autologous haematopoietic stem cell transplantation requires recipient BM macrophages
Kaur, Simranpreet / Raggatt, Liza J. / Jacobsen, Rebecca / Millard, Susan / Barbier, Valerie / Nowlan, Bianca / Winkler, Ingrid G. / MacDonald, Kelli P. / Perkins, Andrew C. / Hume, David A. et al. | 2015
IRF8 inhibits the activity of C/EBPα to restrain mononuclear phagocyte progenitors from differentiating into neutrophils
Kurotaki, Daisuke / Yamamoto, Michio / Nishiyama, Akira / Uno, Kazuhiro / Ban, Tatsuma / Ichino, Motohide / Sasaki, Haruka / Matsunaga, Satoko / Yoshinari, Masahiro / Ryo, Akihide et al. | 2015
Megakaryocyte-platelet induction from mouse embryonic stem cells by enforced expression of Gata2 in late hemogenic endothelial cells
Kawaguchi, Manami / Kitajima, Kenji / Kanokoda, Mai / Suzuki, Hidenori / Nakajima, Marino / Kasahara, Kohji / Hara, Takahiko | 2015
Medial HOXA gene expression is required for establishing “stemness” in human HSCs
Dou, Diana R. / Calvanese, Vincenzo / Sierra, Maria I. / Sasidharan, Rajkumar / Zack, Jerome A. / Crooks, Gay M. / Galic, Zoran / Mikkola, Hanna | 2015
Declined presentation AMPK protects acute myeloid leukemia-initiating cells residing in the bone marrow after metabolic stress
Nakada, Daisuke | 2015
Normal and neoplastic stem cells
Weissman, Irving | 2015
Role of non-canonical polycomb repressive complex 1 in hematopoiesis
Iwama, Atsushi | 2015
DNMT3A and TET2 cooperate and compete to prevent leukemogenesis
Goodell, Margaret A. | 2015
It's all kicking off: Understanding the initiation of childhood leukaemia during pregnancy
Mansell, Els / Case, Patrick | 2015
Identification and functional characterization of early stress erythroid progenitors using novel surface markers and in vivo tracing
Soderberg, Sofie Singbrant / Mattebo, Alexander / Flygare, Johan | 2015
Mitochondrial dynamics regulate lineage potential of hematopoietic stem cells
Luchsinger, Larry / Almeida, Mariana Justino / Snoeck, Hans | 2015
Early activation of TLR2 locus tracks the emergence of embryonic multipotent hematopoietic progenitors which contribute to definitive hematopoiesis
Balounova, Jana / Splichalova, Iva / Dobesova, Martina / Alberich-Jorda, Meritxell / Filipp, Dominik | 2015
Inactivation of EZH2 by trancated form mutaion de-represses novel target genes to promote tumor-initiating capacity
Kawabata, Kimihito Cojin / Inoue, Daichi / Goyama, Susumu / Harada, Hironori / Kitaura, Jiro / Kitamura, Toshio | 2015
Cytotoxic therapies cause irreversible damage to the niches for multipotent progenitor cells, resulting in impaired long-term repopulating potential of bone marrow
Purton, Louise E. | 2015
The AGM and the regulations of hematopoietic stem cell development
Dzierzak, Elaine | 2015
Loss of canonical notch signaling affects multiple steps in natural killer (NK) cell development
Chaves, Patricia / Zriwil, Alya / Boukarabila, Hanane / Jacobsen, Sten Eirik W. / Sitnicka, Ewa | 2015
Improving humanized mice for hematology/hemato-oncology research
Manz, Markus | 2015
Identification of common monocyte progenitors, pre-monocytes, and granulocyte monocyte progenitors in human umbilical cord blood
Kawamura, Shunsuke / Onai, Nobuyuki / Takenaka, Katsuto / Akashi, Koichi / Ohteki, Toshiaki | 2015
Disrupting cdkn1a secondary to FLT3/ITD inhibition is responsible for resistance to FLT3/ITD inhibitor AC220 in FLT3/ITD+ cells
Fukuda, Seiji / Abe, Mariko / Hirade, Tomohiro / Yamaguchi, Seiji | 2015
A novel three-dimensional co-culture system can maintain leukemic hematopoiesis
Balandran, Juan C. / Enciso, Jennifer / Espinoza, Nancy A. / Piña-Sánchez, Patricia / Vadillo, Eduardo / Jimenez-Hernández, Elva / Mayani, Hector / Ortiz-Navarrete, Vianney / Camacho, Rosana Pelayo / Guzma, Monica | 2015
Role of HIFS & ARG2 in hematological malignancy
Pan NG, King / Tan, Qiancheng / Majeed, A'Qilah / Lee, Lin Ming / Chng, Wee Joo / Suda, Toshio | 2015
Elucidating the post-natal role of SCA1+ thymic mesenchymal cells
Patenaude, Julien / Lemieux, Sébastien / Perreault, Claude | 2015
Hepatic leukemia factor is essential for maintaining hematopoietic stem cell function
Komorowska, Karolina / Doyle, Alexander / Soneji, Shamit / Hultmark, Simon / Bryder, David / Mikkola, Hanna / Larsson, Jonas / Magnusson, Mattias | 2015
IFNα promotes differentiation of BCR-ABL+ leukemic cells through upregulating C/EBPβ
Yokota, Asumi / Hirai, Hideyo / Hayashi, Yoshihiro / Tamura, Akihiro / Sato, Atsushi / Iwasa, Masaki / Fujishiro, Aya / Shoji, Tsukimi / Miura, Yasuo / Maekawa, Taira | 2015
Small molecule α9β1/α4β1 integrin antagonist mobilizes hematopoietic stem cells with long-term multilineage engraftment potential
Cao, Benjamin / Zhang, Zhen / Grassinger, Jochen / Williams, Brenda / Nilsson, Susie | 2015
Declined presentation one dose of 5-AZA-2'-Deoxycytidine enhances therapeutic efficacy of cart-cell therapy in a murine model by improving T-cell persistence
Dolnikov, Alla / Yang, Susan / Shen, Sylvie / Xu, Ning / O'Brien, Tracey | 2015
Cohesin genes are critical regulators of HSC renewal
Galeev, Roman / Baudet, Aurelie / Kvist, Anders / Törngren, Therese / Larsson, Jonas | 2015
Protection of telomeres 1 (Pot1) regulates hematopoietic stem cell activity during ageing
Hosokawa, Kentaro / MacArthur, Ben D. / Hanazawa, Shigemasa / Suda, Toshio / Arai, Fumio | 2015
Biological and genetic characterization of the role of SRSF2 mutations in the pathogenesis of myelodysplastic syndromes
Kon, Ayana / Yamazaki, Satoshi / Kataoka, Keisuke / Yoshizato, Tetsuichi / Shiozawa, Yusuke / Sanada, Masashi / Yoshida, Kenichi / Nagata, Yasunobu / Shiraishi, Yuichi / Miyano, Satoru et al. | 2015
The role of CDKN1C/P57KIP2 in developmental haematopoiesis
Kapeni, Chrysa / Ottersbach, Katrin | 2015
Long-term single cell quantification: new tools for old questions
Schroeder, Timm | 2015
Regeneration kinetics of hematopoietic stem cells in wild-type and P53-deficient mice after sublethal cyclophosphamide treatment
Sefc, Ludek / Paral, Petr / Necas, Emanuel | 2015
Interferon regulatory factor-8 (IRF-8) regulates erythroblastic island morphology and function
Yeo, Jia Hao / Xie, Vicki / Campbell, Iain / Fraser, Stuart | 2015
Automated imaging and analysis of hematopoietic CFU assays of mouse bone marrow
Khojasteh, Mehrnoush / Walasek, Marta A. / Wognum, Albertus W. / Szilvassy, Stephen J. / Egeler, Oliver / Woodside, Steven / Poon, Steven / Thomas, Terry / Eaves, Allen | 2015
Virus infections differentially modulate the cell cycle state and functionality of dormant long-term hematopoietic stem cells in vivo
Hirche, Christoph / Frenz, Theresa / Haas, Simon / Brizic, Ilija / Keyser, Kirsten / Döring, Marius / Halle, Stephan / Förster, Reinhold / Jonjic, Stipan / Messerle, Martin et al. | 2015
Histone methyltransferase Setdb1 regulates energy metabolism in hematopoietic stem and progenitor cells
Koide, Shuhei / Takubo, Keiyo / Oshima, Motohiko / Miyagi, Satoru / Saraya, Atsunori / Wang, Changshan / Matsui, Hirotaka / Kimura, Hiroshi / Shinkai, Yoichi / Suda, Toshio et al. | 2015
GATA2 reporter expression reveals stages of esc hematopoietic progenitor generation and facilitates study of GPR56 function
Kauts, M.-L. / Kaimakis, P. / Solaimani, P. / Van der Linden, R. / Dzierzak, E. | 2015
Targeting pre-leukemic stem cells in T-acute lymphoblastic leukemia
Gerby, Bastien / Laflamme, Guillaume / Kwok, Benjamin / Roux, Philippe / Hébert, Josée / Sauvageau, Guy / Hoang, Trang | 2015
A MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate
Gross, Atan / Maryanovich, Maria / Zaltsman, Yehudit | 2015
UP-regulated TCRζ improves cytokine secretion in T cells from patients with AML
Chen, Shaohua / Zha, Xiangfeng / Shi, Li / Yang, Lijian / Li, Bo / Wu, Xiuli / Zhang, Tao / Lu, Yuhong / Zhu, Kanger / Li, Yangqiu | 2015
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis
Cabezas-Wallscheid, Nina / Klimmeck, Daniel / Hansson, Jenny / Lipka, Daniel B. / Reyes, Alejandro / Huber, Wolfgang / Milsom, Michael D. / Plass, Christoph / Krijgsveld, Jeroen / Trumpp, Andreas | 2015
Dynamic boolean model for the bone marrow intercelular regulation in acute lymphoblastic leukemia
Enciso, Jennifer / Mendoza, Luis / Mayani, Hector / Camacho, Rosana Pelayo | 2015
Overexpression of the shortest isoform of histone demethylase LSD1 primes hematopoietic stem/progenitor cells for malignant transformation
Wada, Taeko / Koyama, Daisuke / Kikuchi, Jiro / Honda, Hiroaki / Furukawa, Yusuke | 2015
TIM-3 and its ligand, galectin-9 constitute an autocrine loop to maintain stem cells in most human myeloid malignancies
Akashi, Koichi | 2015
Three-dimensional multicolor imaging of bone marrow cell populations
Kokkaliaris, Konstantinos / Coutu, Daniel / Kunz, Leo / Schroeder, Timm | 2015
Evaluation of stem cell characteristics of adult mouse bone-derived small cells
Nakatsuka, Ryusuke / Matsuoka, Yoshikazu / Sumide, Keisuke / Kawamura, Hiroshi / Fujioka, Tatsuya / Sasaki, Yutaka / Sonoda, Yoshiaki | 2015
T cell-restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of lung macrophages in the lung
Iriguchi, Shoichi / Kikuchi, Norihiro / Noguchi, Emiko / Morishima, Yuko / Matsuyama, Masashi / Yoh, Keigyou / Takahashi, Satoru / Nakauchi, Hiromitsu / Ishii, Yukio / Kaneko, Shin | 2015
Declined presentation single-cell analysis of myelodysplastic sydrome stem cells during therapy and disease progression
Park, Christopher Y. / Vijay, Priyanka / Chung, Stephen S. / Stern, Diana / Klimek, Virginia / Mason, Christopher E. | 2015
ZEB2 drives immature t-cell lymphoblastic leukemia development via enhanced tumor initiating potential and increased IL-7 receptor signaling
Haigh, Jody J. / Goossens, Steven | 2015
Endogenous MLL1 is dispensable for MLL-rearranged leukemia, but promotes acute leukemia driven by other oncoproteins
Chen, Yufei / Li, Bin / Yokoyama, Akihiko / Ernst, Patricia | 2015
Comparative functional analysis of the molecular network of 7 selected MLL fusion proteins
Skucha, Anna / Stukalov, Alexey / Muhar, Matthias / Colinge, Jacques / Bennett, Keiryn / Zuber, Johannes / Superti-Furga, Giulio / Grebien, Florian | 2015
Fibroblastic colony forming units (CFU-F) within adherent cell layer from long-term bone marrow cultures correspond to the progeny of distinct mesenchymal precursor cells
Bigildeev, ALexey / Sats, Natalia / Shipounova, Irina / Petinati, Natalia / Surin, Vadim / Cornils, Kerstin / Riecken, Kristoffer / Aranyossy, Tim / Fehse, Boris / Drize, Nina | 2015
Translational suppression of c-Myb by exosome micro-RNA constrains hematopoietic reserve in the AML NICHE
Hornick, Noah / Doron, Ben / Goloviznina, Natalya / Jianya, Huan / Kurre, Peter | 2015
Genomic studies of marrow failure
Shimamura, Akiko | 2015
Genome-wide DNA methylation profiling reveals two prognostically distinct subgroups of juvenile myelomonocytic leukemia
Lipka, Daniel B. / Witte, Tania / Wiesenfarth, Manuel / Zucknick, Manuela / Konermann, Carolin / Gu, Lei / Claus, Rainer / Nöllke, Peter / Niemeyer, Charlotte / Flotho, Christian et al. | 2015
SOX17 is critical for the maintenance of stem cell phenotype of intra-aortic hematopoietic clusters of cells in the aorta-gonad-mesonephros region
Nobuhisa, Ikuo / Osawa, Mitsujiro / Uemura, Mami / Harada, Kaho / Anani, Maha / Saito, Kiyoka / Takagi, Haruna / Takahashi, Satomi / Kanai-Azuma, Masami / Kanai, Yoshiakira et al. | 2015
Roe of CBAP in controlling proliferation and development of T-cell acute lymphoblastic leukemia
Chiang, Yun-Jung / Ho, Kun-Chin / Yang-Yen, Hsin-Fang / Yen, Jong-Young J. | 2015
STAT5-regulated microrna-193B controls hematopoietic stem cell expansion and leukemogenesis by modulating cytokine receptor signaling
Haetscher, Nadine / Feuermann, Yonatan / Wingert, Susanne / Rehage, Maike / Thalheimer, Frederic B. / Bohnenberger, Hanibal / Mohr, Sebastian / Schroeder, Timm / Serve, Hubert / Oellerich, Thomas et al. | 2015
A novel link between spliceosomal dysfunction and inflammation
Cameron, Rosannah C. / De, Adriana / Garza, La / Bowman, Teresa V. | 2015
Rejuvenation of aged hematopoietic stem cells by restoring the asymmetry of division
Florian, M.Carolina / Nattamai, Kalpana / Soller, Karin / Marka, Gina / Zheng, Yi / Geiger, Hartmut | 2015
Specific amino acid environments of bone marrow are crucial for the maintenance of hematopoietic stem cells
Yamazaki, Satoshi / Nakauchi, Hiromitsu | 2015
Declined presentation the effects of interferon α-2b on defective bone marrow mesenchymal stem cells in patients with essential thrombocythemia
Sun, Tiantian / Lv, Cuicui / Zhang, Donglei / Lv, Mingen / Zhang, Xian / Liu, Wenjie / Fu, Rongfeng / Li, Huiyuan / Xue, Feng / Liu, Xiaofan et al. | 2015
Human cord blood-derived primitive CD34-negative hematopoietic stem cells (HSCs) are myeloid-biased long-term HSCs residing at the apex of human HSC hierarchy
Matsuoka, Yoshikazu / Sumide, Keisuke / Kawamura, Hiroshi / Nakatsuka, Ryusuke / Fujioka, Tatsuya / Sasaki, Yutaka / Sonoda, Yoshiaki | 2015
P-selectin expression and platelet function are developmentally regulated
Palis, James / Stolla, Massiel / McGrath, Kathleen E. / Kingsley, Paul D. | 2015
AGE-associated clonal dominance of myeloid-biased HSC is underwritten by unique transcriptional and epigenetic alterations
Beerman, Isabel / Ziller, Michael / Vandiver, Amy / Gaudin, Raphael / Kirchhausen, Tomas / Feinberg, Andrew / Meissner, Alexander / Rossi, Derrick | 2015
Development of thrombocytes from the megakaryocyte induced by thrombopoietin in frog
Tanizaki, Yuta / Murase, Ayaka / Mochizuki, Yoko / Otani, Takato / Kato, Takashi | 2015
Assessing the roles of cell cycle checkpoints in HSC
Brown, Andreas / Pospiech, Johannes / Moehrle, Bettina / Martin, Nicola / Geiger, Hartmut | 2015
The polarity protein, PAR3, is a key regulator of haematopoietic progenitors
Dew, Alysha / Borg, Judy / Adolph, Leah / Russell, Sarah / Walkley, Carl / Purton, Louise E. / Ellis, Sarah L. | 2015
Mesenchymal stem cells from patients with CMML display impaired hematopoietic supportive activity
Shi, Hui / Li, Rong / Xing, Wen / Bai, Jie / Cheng, Tao / Yang, Fengchun / Zhou, Yuan | 2015
M-CSF instructs both cell division and cell identity in HSC through independent transcription factor circuits
Sarrazin, Sandrine / Kandalla, Prashanth K. / Mossadegh-Keller, Noushine / Espinosa, Leon / Sieweke, Michael | 2015
Inhibition of GPR56 by PI-polyamide targeting the evi1-binding site with suppression of leukemia
Kaneda, Kazuko N. / Saito, Yusuke / Suekane, Akira / Shimosaki, Shunsuke / Morishita, Kazuhiro | 2015
Targeting intracellular trafficking of FLT3-ITD and KIT D816V by chlorpromazine shows promising preclinical activity against acute myeloid leukemia cells
Rai, Shinya / Tanaka, Hirokazu / Watanabe, Toshio / Kanakura, Yuzuru / Matsumura, Itaru | 2015
Role of septins in HSC aging
Senger, Katharina / Florian, M.Carolina / Geiger, Hartmut | 2015
Dietary created niche for non-myeloablative hematopoietic stem cell transplantation
Nakauchi, Hiromitsu | 2015
Local and systemic regularors of aging phenotypes in mammalian tissues
Wagers, Amy J. | 2015
CLEC-2 signaling is crucial for the production of thrombopoietin in the megakaryocyte niche
Nakamura-Ishizu, Ayako / Suda, Toshio | 2015
Noncoding RNA regulation of myeloid transcription factors, DNA methylation, and leukemia
Tenen, Daniel G. | 2015
Genetic fate mapping of mesenchymal stem-like cells in the aorta-gonad mesonephros (AGM) and their contribution to developmental hematopoiesis
Chandrakanthan, Vashe / Knezevic, Kathy / Kang, Young C. / Qiao, Qiao / Pimanda, John | 2015
Monitoring GM-CSF receptor/JAK2 activation in real time by live cell super-resolution fluorescence imaging
Yen, Jong-Young J. / Liu, Chun-Shan / Chien, FanChing / Hsieh, Thung-Han | 2015
Declined presentation P38α–activated purine metabolism plays a crucial role in proliferation of transplanted hematopoietic stem cells
Takubo, Keiyo | 2015
Role of long non-coding RNA PVT1 in proliferation of acute promyelocytic leukemia
Zeng, Chengwu / Yu, Xibao / Cheng, Jingjing / Xu, Ling / Li, Yangqiu | 2015
The signaling balance between lysophosphatidic acid receptor 1 and 3 in bone marrow-derived mesenchymal stem cells determines progression of multiple myeloma
Kanehira, Masahiko / Fujiwara, Tohru / Nakajima, Shinji / Okitsu, Yoko / Onishi, Yasushi / Fukuhara, Noriko / Ichinohasama, Ryo / Harigae, Hideo | 2015
Functional perturbations in mesenchymal stromal cells from patients with acute myeloid leukemia and following high-dose irradiation
Le, Y. / Chandran, P. / Richardson, R. / Allan, D. | 2015
CDX2 regulates human leukemic cell clonogenicity and in vivo leukemia initiation
Paczulla, Anna / Quintanilla-Martinez, Leticia / Kanz, Lothar / Lengerke, Claudia | 2015
Declined presentation the role of c-Myc in regulating microenvironment for erythropoiesis and megkaryocytopoiesis
Hayashi, Yoshihiro / Wu, Lingyun / Huang, Gang | 2015
Linking heme biosynthesis with a GATA factor-regulated genetic network that controls cellular differentiation
Tanimura, Nobuyuki / Miller, Eli / Igarashi, Kazuhiko / Burstyn, Judith N. / Dewey, Colin N. / Bresnick, Emery H. | 2015
Reprogramming primary human mature B-cells into induced pluripotent stem cells
Bueno, Clara / Sardina, Jose Luis / Romero-Moya, Damià / Muñoz-Lopez, Alvaro / Di Stefano, Bruno / Quintana-Bustamante, Oscar / Segovia, Jose Carlos / Nakanishi, Mahito / Graf, Thomas / Menéndez, Pablo | 2015
Characterization of microglia-like cells derived from mouse bone marrow cells for new therapeutic strategy of alzheimer’s disease
Kawanishi, Shohei / Takata, Kazuyuki / Takada, Tetsuya / Kitamura, Yoshihisa / Ashihara, Eishi | 2015
Analysis of notch signalling activity during hematopoietic stem cell development
Gonzalez, Javier / Lendinez, Javier G. / Souilhol, Celine / Rybtsov, Stanislav / Hills, David / Zhao, Suling / Medvinsky, Alexander | 2015
NUP98-HOXA10HD knock in model: a good tool for the biology and regeneration of hematopoietic stem cells
Dong, Yong / Xia, Chengxiang / Fang, Shumin / Liu, Xiaofei / Yang, Dan / wang, Jinyong | 2015
Identifying mechanisms that limit efficient site-specific gene modification by homology-directed repair in hematopoietic stem cells
Bjurström, Carmen F. / Mojadidi, Michelle / Campo, Beatriz / Reik, Andreas / Holmes, Michael C. / Cost, Greg / Gregory, Philip D. / Hoban, Megan D. / Hollis, Roger P. / Kohn, Donald B. | 2015
Unraveling the mechanisms underlying the refractoriness of MLL-rearranged acute B-cell leukemias to reprogramming into pluripotency
Bueno, Clara / Romero-Moya, Damià / Muñoz-Lopez, Alvaro / van Roon, E. / Ramos, V. / Agraz, A. / Varela, I. / Ariza, L. / Castaño, J. / Giorgetti, A. et al. | 2015
Modeling myeloid malignancies with human induced pluripotent stem cells
Papapetrou, Eirini | 2015
Executive functions of the cascular niche in hematopoietic specification maintenance and regeneration
Rafii, Shahin | 2015
Notch signal strength controls endothelial to hematopoietic transition
Bigas, Anna | 2015
Metabolic regulation of hematopoietic stem cells by the bone marrow microenvironment
Lapidot, Tsvee | 2015
Primitive macrophages control HSPC mobilisation and definitive haematopoiesis
Kissa, Karima | 2015
The imaging of the bone marrow and hematopoietic stem cells
Kunisaki, Yuya | 2015
Rapid formation of B cell leukemia in mice expressing the PAX5-JAK2 fusion protein
Jurado, Sabine / Kostanova, Daniela / Busslinger, Meinrad | 2015
CD90 expression in mesenchymal stem cells of the malignant niche
Jaganathan, Bithiah G. / Kumar, Atul / Bhattacharyya, Jina | 2015
Amino acid metabolism in myeloid leukemia
Hattori, Ayuna / Ito, Takahiro | 2015
Unraveling the importance of the post-transcriptional RNA regulon in leukemic stem cells by in vivo RNAi
de Rooij, Laura / Belew, Muluken / Hope, Kristin | 2015
Identification of the human unipotent megakaryocyte progenitor, and its pathophysiological roles in human thrombopoietic disorders
Miyawaki, Kohta / Iwasaki, Hiromi / Akashi, Koichi | 2015
Developing therapeutic strategies targeting poor prognosis acute myeloid leukemia
Ishikawa, Fumihiko | 2015
Microrna can completely rescue b lineage commitment arrest due to early B cell factor 1 deficiency—can micrornas control cell fate as an alternative to transcription factors?
Chanda, B. / Kotani, Ai | 2015
Non-coding RNA editase deregulation as a driver of leukemia stem cell generation
Jamieson, Catriona | 2015
Serotonin regulates HSC formation via glucocorticoid production from the hypothalamic-pituitary-interrenal axis
Kwan, Wanda / Cortes, Mauricio / Liu, Sarah Y. / Goessling, Wolfram / North, Trista E. | 2015
Declined presentation Dendritic cell vaccination as a post-remission treatment in acute myeloid leukemia
Berneman, Zwi / de Velde, Ann Van / Anguille, Sébastien / Nijs, Griet / Stein, Barbara / Cools, Nathalie / Vermeulen, Katrien / Maes, Marie-Berthe / Willemen, Yannick / Granacher, Nikki et al. | 2015
Leukemic mesenchymal stem cells impedes the generation of normal hematopoietic progenitor cells
Lim, Meikuang / Pang, Yakun / Ma, Shihui / Hao, Sha / Shi, Hui / Zheng, Yawei / Hua, Chunlan / Yang, Fengchun / Yuan, Weiping / Cheng, Tao | 2015
Conserved transcriptional programmes regulating blood cell development
Wilkinson, Adam C. / Tanaka, Yosuke / Wang, Wei / Ryan, David J. / Liu, Pentao / Gottgens, Bertie | 2015
Dynamic expression of B7 family molecules on hematopoietic stem cells
Iida, Ryuji / Garrett, Karla / Alberola-lla, José / Kohara, Arihiro / Kincade, Paul | 2015
Targeted single copy Runx1 reporter lines for interrogation and enhancement of definitive hematopoiesis from murine pluripotent stem cells
Webber, Beau R. / Tolar, Jakub / Kyba, Michael / Blazar, Bruce R. | 2015
Homeostatic regulation of hematopoietic stem cells by the interaction of niche factors
Ieyasu, AKi / Yamazaki, Satoshi / Nakauchi, Hiromitsu | 2015
Oncogenic micrornas in cerberospinal fluid: Sensitive tool for detection of CNS lymphoma, estimation of therapy efficacy and prediction of CNS relapse
Pospisil, Vitek / Mocikova, Heidi / Trneny, Marek / Stopka, Tomas | 2015
Modulation of macrophages by tumor-derived secretary small RNAs is critical for EBV positive lymphoma formation
Yamakawa, Natsuko / Imadome, Ken-Ichi / Yahata, Takashi / Kotani, Ai | 2015
Cytokine signalling in developmental haematopoiesis reveals resistance of embryonic haematopoietic stem cells to myeloproliferative disease-associated mutation
Mascarenhas, Maria I. / Bacon, Wendi A. / Kapeni, Chrysa / Fitch, Simon R. / Li, Juan / Green, Anthony R. / Ottersbach, Katrin | 2015
Ihstone H3 lysine 9 methylation is involved not only in maintaining epigenetic silencing, but is essential for setting up gene silencing
Keniry, Andrew / Gearing, Linden / Jansz, Natasha / Liu, Joy / Kinkel, Sarah / Breslin, Kelsey / Moore, Darcy / Chen, Kelan / Pakusch, Miha / Willson, Tracy et al. | 2015
Maintenance of hematopoietic stem and progenitor cell phenotype of intra-aortic cell clusters in the AGM region through the Sox17-Notch1-Hes1 axis
Saito, Kiyoka / Nobuhisa, Ikuo / Anani, Maha / Harada, Kaho / Takahashi, Satomi / Taga, Tetsuya | 2015
Chromatin remodeling factor BRM is essential for the maintenance of HSC quiescence
Nitta, Eriko / Yamashita, Masayuki / Oshima, Motohiko / Iwama, Atsushi / Suda, Toshio | 2015
Dynamic in vivo measurement of acute lymphoblastic leukaemia interactions within bone marrow microenvironments
Lo Celso, Cristina | 2015
Optical techniques for characterizing the bone marrow microenvironment
Lin, Charles P. | 2015
Migration and characteristics of thrombocytes during cold-exposure in xenopus laevis
Murase, Ayaka / Kashiwase, Nao / Tanizaki, Yuta / Otani, Takato / Mochizuki, Yoko / Kato, Takashi | 2015
Characteristic of HLA-G and Th17/Tregs axis associated regulatory factors expression pattern in adult B cell acute lymphoblastic leukemia
Wu, Xiuli / Wang, Xinyu / Jin, Zhenyi / Hu, Junyan / Chen, Shaohua / Yang, Lijian / Li, Yangqiu | 2015
Cyclin D1/CDK4-, but not cyclin E1/CDK2-mediated acceleration of G1 cell cycle phase transit time provides a competitive advantage for human hematopoietic stem cells in vivo
Mende, Nicole / Waskow, Claudia | 2015
High frequency mutation of 3’-UTR related to abnormal expression of CD3ζ in patients with aplastic anemia
Li, Bo / Fang, Su / Guo, Lixing / Liao, Ziwei / Wu, Mingjuan / Chen, Shaohua / Yang, Lijian / Lu, Xiang / Li, Yangqiu | 2015
Probing co-operating somatic mutations in MLL-ENL driven myeloid leukemogenesis
Ugale, Amol S. / Adolfsson, Sofia / Säwen, Petter / Cammenga, Jörg / Bryder, David | 2015
Long-term-repopulating hematopoietic stem cells are dispensable in steady state but essential for stress hematopoiesis
Gerbaulet, Alexander / Schoedel, Kristina / Zerjatke, Thomas / Roeder, Ingo / Voehringer, David / Göthert, Joachim / Waskow, Claudia / Roers, Axel | 2015
ATF4 is a positive regulator for hematopoietic stem cells partially via Angptl3 in mouse fetal liver microenvironment
Zhao, Yunze / Zhou, Jie / Dong, Fang / Cheng, Hui / Wang, Weili / Pang, Yakun / Mu, Xiaohuan / Ni, Yanli / Li, Zhuan / Xu, Huiyu et al. | 2015
Context-dependent effect of neuropilin-1 on the regulation of HSC fate
Ghode, Suprita S. / Bajaj, Manmohan / Limaye, Lalita / Kale, Vaijayanti | 2015
Fanconi anemia pathway safeguards interphase and mitosis in vivo
Cerabona, Donna / Sater, Zahi A. / Potchanant, Elizabeth Sierra / Sun, Zejin / He, Ying / Nalepa, Grzegorz | 2015
Surface CD45 expression levels distinguish normal erythroblasts from stress erythroblasts during haemolytic anaemia and pregnancy-induced anaemia
Colonne, Chanukya K. / Yao, Jia Hao / Pilgrim, Chelsea / Williams, Henry / Fraser, Stuart | 2015
Allogeneic T cells disrupt medullary thymic epithelial cell formation and indirectly lead to chronic graft-vs-host disease
Mueller, Antonia M. / Min, Dullei / Burnett, Casey / Florek, Mareike / Weinberg, Kenneth / Shizuru, Judith A. | 2015
Localization and characterization of hematopoietic cells in the mouse embryonic head
Li, Zhuan / Vink, Chris S. / Mariani, Samanta / Dzierzak, Elaine | 2015
CD14 mediates phagocytic activity during the granulocytic differentiation process in acute promyelocytic leukemia cells
Hsu, Hui-Chi | 2015
Role of spred1 in the regulation of self-renewal and aging of hematopoietic stem cells
Tadokoro, Yuko / Yoshimura, Akihiko / Nakauchi, Hiromitsu / Hirao, Atsushi | 2015
Lymph node-associated stromal fibroblasts as a potential source of humoral factors to support B-cell lymphoma cells via the phosphatidylinositol 3-kinase pathway
Sakamoto, Akihiko / Shimada, Kazuyuki / Katayama, Miyuki / Hayakawa, Fumihiko / Tomita, Akihiro / Kiyoi, Hitoshi | 2015
Enhancer landscape dynamics during monocyte and dendritic cell development and the role of the transcription factor IRF8
Kurotaki, Daisuke / Nakabayashi, Jun / Nishiyama, Akira / Sasaki, Haruka / Kaneko, Naofumi / Koizumi, Shin-ichi / Ozato, Keiko / Suzuki, Yutaka / Tamura, Tomohiko | 2015
Rictor is pivotal for the emergence and function of embryonic hematopoietic stem cells
Wang, Weili / He, Wenyan / Mu, Xiaohuan / Zhou, Jie / Ni, Yanli / Zhao, Yunze / Wang, Xiaomin / Wang, Qianfei / Cheng, Tao / Liu, Bing et al. | 2015
Identification of runx1-direct targets important for definitive hematopoiesis
Tanaka, Yosuke / Moignard, Victoria / Wilkinson, Adam C. / Hannah, Rebecca / Ladopoulos, Vasileios / Gottgens, Bertie | 2015
Enforced expression of RPS19 derived from human elongation factor 1A short (EFS) promoter corrects the anemia and lethal bone marrow failure in mouse model for RPS19-deficient diamond-blackfan anemia
Debnath, Shubhranshu / Jaako, Pekka / Siva, Kavitha / Modlich, Ute / Schambach, Axel / Gaspar, Bobby / Flygare, Johan / Karlsson, Stefan | 2015
The GATA2 transcription factor directly binds and activates MYB expression in acute myeloid leukemia
Cortés-Lavaud, Xabier / Vicente, Carmen / Urquiza, Leire / González, Marcos / Calasanz, María J. / Barragán, Eva / García-Sánchez, María A. / Dzierzak, Elaine / Odero, María D. | 2015
Declined presentation hematopoietic signaling mechanism revealed from a stem/progenitor cell cistrome
Hewitt, Kyle / Kim, Duk Hyoung / Prathibha, Rajalekshmi / Devadas, Prithvia / Zuo, Chandler / Sanalkumar, Rajendran / Kang, Yoon-A / Johnson, Kirby / Kim, Jin-Soo / Dewey, Colin N. et al. | 2015
Kit deficiency regulates stable human hematopoietic stem cell engraftment in mice
Rahmig, Susann / Nevmerzhitskaya, Aleksandra / Waskow, Claudia | 2015
Table of Contents
| 2015
Modeling the function of the cohesin complex in hematopoietic stem cell differentiation and transformation
Aifantis, Iannis | 2015
Making blood: The organized labor of multiple niches
Scadden, David | 2015
Angiogenesis revisited: Endothelial cell metabolism as a target?
Carmeliet, Peter | 2015
Deciphering the role of retinoic acid receptor signalling in haematopoietic stem cells
Lauridsen, Felicia K. / Porse, Bo | 2015
Characteristics of stromal stem cells in the foetal liver
Qiao, Qiao / Chandrakanthan, Vashe / Pimanda, John | 2015
Control of mitochondrial load and oxidative stress by tp53 during developmental erythropoiesis
Carter, Michelle / Kramer, Ashley / Lund, Troy | 2015
An investigation of the leukaemia initiating cell in TRIB2 mediated AML
Pellicano, Francesca / O'Connor, Caitriona / Keeshan, Karen | 2015
Declined presentation T-cell precursors to generate chimeric antigen receptor (CAR)-modified t cells
Dolnikov, Alla / Shen, Sylvie / Xu, Ning / Yang, Susan / O'Brien, Tracey | 2015
Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma
Kikuchi, Jiro / Koyama, Daisuke / Wada, Taeko / Izumi, Tohru / Hofgaard, Peter O. / Bogen, Bjarne / Furukawa, Yusuke | 2015
Declined presentation stem cell approach to generate chimeric antigen receptor modified immune effector cells
Dolnikov, Alla / Shen, Sylvie / Xu, Ning / Yang, Susan / O'Brien, Tracey | 2015
From HSC to megakaryocyte: differential role of the cellular components of the fetal liver microenvironment
Egard, Sebastien / Strassel, Catherine / Lanza, François / Gachet, Christian / Brouard, Nathalie | 2015
Musashi-2 postranscriptionally attenuates aryl hydrocarbon receptor signaling to expand human hematopoietic stem cells
Rentas, Stefan / Holzapfel, Nicholas / Belew, Muluken / Voisin, Veronique / Pratt, Gabriel / Bader, Gary / Yeo, Gene / Hope, Kristin | 2015
Bile acids support expanding hematopoietic stem/progenitor cells in the fetal liver
Sigurdsson, Valgardur / Takei, Hajime / Soboleva, Svetlana / Siva, Kavitha / Galeev, Roman / Leeb-Lundberg, Fredrik / Iida, Takashi / Nittono, Hiroshi / Miharada, Kenichi | 2015
The transmembrane protein EVI2B regulates hematopoietic stem cell function
Zjablovskaja, Polina / Kardosova, Miroslava / Benoukraf, Touati / Brdicka, Tomas / Balastik, Martin / Tenen, Daniel / Malissen, Bernard / Horejsi, Vaclav / Alberich-Jorda, Meritxell | 2015
The focal adhesion protein ilk is key to niche interactions and survival of CML stem cells
Rothe, Katharina / Watanabe, Akie / Forrest, Donna / Dedhar, Shoukat / Eaves, Connie / Jiang, Xiaoyan | 2015
Assessment of candidate microRNAs to supress leukemic cell function using an inducible lentiviral vector system
Ruschmann, Jens / Maetzig, Tobias / Krowiorz, Kathrin / Kuchenbauer, Florian / Petriv, Oleh / Hansen, Carl / Humphries, Keith | 2015
Novel roles of ASXL1 in epigenetic regulation
Inoue, Daichi / Horikawa, Sayuri / Matsui, Hirotaka / Nagase, Reina / Saika, Makoto / Kawabata, Kimihito C. / Goyama, Susumu / Kitamura, Toshio | 2015
Declined presentation PRMT5 methyltransferase activity is required to sustain adult hematopoiesis
Nimer, Stephen D. / Liu, Fan / Cheng, Guoyan / Perna, Fabiana / Haiming, Xu / Hamard, Pierre-Jacques / Luciani, Luisa / Nimer, Stephen | 2015
Unravelling the molecular events leading to hematopoietic stem cell generation in the mouse embryo aorta
Baron, Chloe / Kester, Lennart / Boisset, Jean-Charles / van Oudenaarden, Alexander / Robin, Catherine | 2015
Differentiation targeted compound screen of acute myeloid leukemia
Baudet, Aurelie / Ek, Fredrik / Davidsson, Josef / Soneji, Shamit / Olsson, Roger / Cammenga, Jörg / Magnusson, Mattias / Juliusson, Gunnar | 2015
Title to come
| 2015
The microenvironmental niches for hematopoietic stem and progenitor cells in bone marrow
Nagasawa, Takashi | 2015
Hematopoietic stem cell production and regulation in the embryo aorta
Robin, Catherine | 2015
Anti tumor activity of fucoidan in acute promyelocytic leukemia and its synergy with arsenic trioxide and ATRA in vitro and in vivo
Atashrazm, Farzaneh / Lowenthal, Ray M. / Woods, Greg M. / Holloway, Adele F. / Dickinson, Joanne L. | 2015
Introduction of hematopoietic stem cell niche
Arai, Fumio | 2015
The prognostic significance of tumor-associated macrophages and NK cells in patients with diffuse large B-cell lymphoma treated with RCHOP
Feng, Ru | 2015
Glasgow prognostic score is superior to other inflammation-based scores in predicting survival of diffuse large B-cell lymphoma
Feng, Ru | 2015
Defining the role of the phosphatase of regenerating liver enzymes in the immune system
Hatzihristidis, Teri / Uetani, Noriko / Hardy, Serge / Sirois, Jacinthe / Tremblay, Michel L. | 2015
A role of the transcription factor IRF8 in basophil and mast cell development
Sasaki, Haruka / Kurotaki, Daisuke / Osato, Naoki / Sato, Hideaki / Sasaki, Izumi / Koizumi, Shin-ichi / Wang, Hongsheng / Kaneda, Chika / Nishiyama, Akira / Kaisho, Tsuneyasu et al. | 2015
A new gene transfer system for hematopoietic stem cells under physiological condition
Tajima, Yoko / Yamazaki, Satoshi / Nakauchi, Hiromitsu | 2015
Dynamics of hematopoietic cell cluster emergence in hemogenic endothelium
Zape, Joan M. / Lizama, Carlos / Bos, Frank / Hawkins, John / Zovein, Ann C. | 2015
Overcoming quiescence by targeting p21 (Cdkn1a) sensitizes pre-leukemic stem cells to chemotherapy
Tremblay, Cedric S. / Saw, Jesslyn / Chiu, Sung K. / Curtis, David | 2015
Abnormalities in nestin-expressing bone marrow stromal cells in patients with myelodysplastic syndrome
Obara, Naoshi / Chiba, Shigeru / Kato, Takayasu / Sakamoto, Tatsuhiro / Cao, Luan / Suzuki, Sachie / Kurita, Naoki / Yokoyama, Yasuhisa / Sakata, Mamiko / Hasegawa, Yuichi | 2015
Blood cells form from phenotypically distinct precursors during human blast colony differentiation
Bruveris, Freya / Ng, Elizabeth / Azzola, Lisa / Stanley, Edouard / Elefanty, Andrew | 2015
TRGV and TRDV repertoire distribution and clonality of γδ T cells in patients with AML
Jin, Zhenyi / Wu, Xiuli / Wang, Xinyu / Hu, Junyan / Chen, Shaohua / Yang, Lijian / Li, Yangqiu | 2015
Lympho-hematopoietic microenvironment regulated by inter-organ communication
Katayama, Yoshio | 2015
The dynamic interplay of GATA zinc-fingers in blood development and disease
Nurmohamed, Salima | 2015
Development of human hemato-lymphoid system in human cytokine knock-IN RAG2-/-IL2RG-/- mice engrafted with peripheral blood mobilized CD34+ cells
Saito, Yasuyuki / Ellegast, Jana M. / Kull, Daniel / Heikenwälder, Mathias / Flavell, Richard A. / Manz, Markus G. | 2015
Hemogenic endothelium-like changes were observed in an adult human dermal fibroblast with poly (I:C) and an electrical stimulation
Matsuo, Takuji / Sumiyoshi, Rhitsu / Shirasaki, Ryosuke / Yamamoto, Tadashi / Oka-Miura, Yoko / Matsumoto, Kennsuke / Ooi, Jun / Shirafuji, Naoki | 2015
The dominant mechanism of prenatal platelet-formation is not via proplatelet intermediates but by direct release
Potts, Kathryn S. / Dawson, Caleb A. / Taoudi, Samir | 2015
Stem cell factor, GM-CSF, and IL-3-Transgenic humanized mice develop fatal hemophagocytic lymphohistiocytosis
Yoshihara, Satoshi / Li, Yuying / Xia, Jinxing / Li, Wei / Fujimori, Yoshihiro / Yang, Yong-Guang | 2015
Stroma-derived osteopontin regulates HSC aging
Guidi, Novella / Sacma, Mehmet / Soller, Karin / Marka, Gina / Weiss, Johannes / Cancelas, Jose / Florian, M.Carolina / Geiger, Hartmut | 2015
SSB1 and SSB2 single-stranded DNA binding proteins are essential for HSC function
Vu, Therese / Shi, Wei / Lane, Steven / Khanna, Kum Kum | 2015
Declined presentation high HIF-1α level results in murine MDS/MPN or HLH in different mouse backgrounds
Hayashi, Yoshihiro / Yan, Xiaomei / Xiao, Zhijian / Huang, Gang | 2015
The role of Gata3 in blood stem cell emergence
Zaidan, Nada M. / Fitch, Simon R. / Ottersbach, Katrin | 2015
Renin-angiotensin system is involved in hematopoietic emergence
Julien, Emmanuelle / Lanza, François / Gachet, Christian / Tavian, Manuela | 2015
No hierarchical heterogeneity in adult B-ALL lymphoid neoplasia
Jiang, Zhiwu / Deng, Manman / xu, Bing / Li, Peng | 2015
Maintenance and expansion of human hematopoietic stem and progenitor cells in the presence of defined factors alone
Sudo, Kazuhiro / Yamazaki, Satoshi / Nakauchi, Hiromitsu / Nakamura, Yukio | 2015
Declined presentation Vβ17 T cell clones may respond to ABL-T315I mutation protein in chronic myeloid leukemia in blastic crisis
Xu, Ling / Chen, Jie / Zhang, Tao / Zha, Xianfeng / Chen, Shaohua / Yang, Lijian / Lu, Yuhong / Zhu, Kanger / Li, Yangqiu | 2015
Endothelial cell-selective adhesion molecule is a novel human hematopoietic stem cell marker associated with a subset of human leukemias
Ishibashi, Tomohiko / Yokota, Takafumi / Tanaka, Hirokazu / Ichii, Michiko / Sudo, Takao / Satoh, Yusuke / Doi, Yukiko / Tanimura, Akira / Hamanaka, Yuri / Ezoe, Sachiko et al. | 2015
Comparative RNA-seq analyses identify new microRNA biomarkers and candidate target genes in patients’ drug-resistant CD34+ CML stem/progenitor cells
Lin, Hanyang / Rothe, Katharina / Ruschmann, Jens / Petriv, Oleh / O'Neill, Kieran / Knapp, David / Brinkman, Ryan / Birol, Inanc / Forrest, Donna / Hansen, Carl et al. | 2015
Dual function of fumarate hydratase in haematopoietic stem cell fates
Guitart, Amelie V. / Vukovic, Milica / Sepulveda, Catarina / Panagopoulou, Theano / Allen, Lewis / Pollard, Patrick / Morton, Nik / Finch, Andy / Kranc, Kamil | 2015
Tissue-resident macrophages originate from yolk sac-derived erythro-myeloid progenitors
Perdiguero, Elisa Gomez / Klapproth, Kay / Schulz, Christian / Busch, Katrin / Azzoni, Emanuele / Crozet, Lucile / Garner, Hannah / Trouillet, Celine / De Bruijn, Marella / Geissmann, Frederic et al. | 2015
Induction of stem cell features in all cells by microenvironmental factors
Bendall, Linda / Baraz, Rana / Tong, Carl / Welschinger, Robert / Basnett, Jordan / Law, Tamara / Sutton, Rosemary / Bradstock, Kenneth | 2015
The international staging system predicts outcome in diffuse large B-cell lymphoma treated with R-chop
Feng, Ru | 2015
Declined presentation recombinant human thrombopoietin promotes hematopoietic reconstitution in mice
Li, Yanhua / Wang, Chao / Zhang, Bowen / Wang, Sihan / He, Lijuan / Pei, Xuetao | 2015
Factors released by megakaryocytes thrombin cleave osteopontin to negatively regulate hematopoietic stem cells
Heazlewood, Shen / Storan, Melonie / Heazlewood, Chad / Cao, Benjamin / Alexander, Warren / Neaves, Rebecca / Oteiza, Ana / Nilsson, Susie | 2015
A novel 3D prostate cancer bone marrow metastasis in vitro model system
Othman Mosaad, Eman Mohamed / Chambers, Karen / Clements, Judith / Doran, Michael R. | 2015
Fanconi anemia and bone marrow failure
D'Andrea, Alan D. | 2015
Stem cell in cancer: Do they matter?
Dick, John E. | 2015
Distinct and non-overlapping functions of Llgl1 and scribble in hematopoietic stem cells
Mohr, Juliane / Frey, Stephanie / Bullinger, Lars / Schnoeder, Tina M. / Weinert, Soenke / Huber, Tobias B. / Kaehne, Thilo / Armstrong, Scott A. / Fischer, Thomas / Heidel, Florian H. | 2015
Granulocyte-colony stimulating factor specifically mobilizes dormant hematopoietic stem cells without proliferation
Bernitz, Jeff / Moore, Kateri | 2015
Physiologic stress drives accelerated aging of hematopoietic stem cells
Milsom, Michael D. | 2015
Genome-wide RNA tomography analysis of the microenvironment promoting hematopoietic stem cell emergence in the embryo aorta
Yvernogeau, Laurent / Junker, Jan Philipp / van Oudenaarden, Alexander / Robin, Catherine | 2015
The zebrafish homologue of the murine EVI1 gene critically regulates hsc development
Konantz, Martina / Müller, Joëlle / Lenard, Anna / Esain, Virginie / North, Trista E. / Lengerke, Claudia | 2015
Role of the polycomb gene BCOR in hematopoiesis
Tanaka, Tomoyuki / Nakajima-Takagi, Yeako / Oshima, Motohiko / Saraya, Atsunori / Tara, Shiro / Si, Sha / Sone, Hirohito / Koseki, Haruhiko / Iwama, Atsushi | 2015
PDGF-AB and azacitidine induced reprogramming of somatic cells into tissue regenerative multipotent stem cells
Chandrakanthan, Vashe / Jair, Kwan / Oliver, Rema / Qiao, Qiao / Kang, Young C. / Zarzour, Peter / Beck, Dominik / Boelen, Lies / Unnikrihnan, Ashwin / Villanueva, Jeanette et al. | 2015
Investigation of the role of TRIB2 in normal murine hematopoiesis
Liang, Kai Ling / O'Connor, Caitriona / McCarthy, Tommie V. / Keeshan, Karen | 2015
Inclusion of conditioned medium of mesenchymal stem cells in the freezing medium imparts cryoprotective effect on the ex vivo expanded umbilical cord blood cells
Kadekar, Darshana / Rangole, Sonal / Kale, Vaijayanti / Limaye, Lalita | 2015
A novel role for the EMT regulator, snai1, in hematopoiesis and leukemia
Carmichael, Catherine / Goossens, Steven / Kile, Benjamin / Haigh, Jody J. | 2015
Micromarrow-direct bone marrow transplantation; using 3D mesenchymal stem/stromal cell (MSC) derived microtissues as a biological anchor to enhance haematopoietic stem cell (HSC) direct bone marrow delivery and engraftment
Futrega, Kathryn / Lott, William B. / Doran, Michael R. | 2015
Chloroquine inhibits autophagy and induces the apoptosis of primary effusion lymphoma via ER stress
Alam, Md. Masud / Kariya, Ryusho / Matsuda, Kouki / Okada, Seiji | 2015
A low-input, multiplexed assay for quantitative comparison of chromatin landscapes
van Galen, Peter / Ram, Oren / Ryan, Russel J. / Cotton, Matthew J. / Donohue, Laura / Drier, Yotam / Sievers, Cem / Gillespie, Shawn M. / Bernstein, Bradley E. | 2015
A new strategy for manipulating expression and activity of geminin could make it possible to regulate cell fates of HSCs
Takihara, Yoshihiro / Ohno, Yoshinori / Suzuki-Takedachi, Kyoko / Kurogi, Toshiaki / Santo, Mimoko / Naka, Kazuhito / Yasunaga, Shin’ichiro | 2015
Axolotl hematopoietic stem cells share similar functional characteristics with their mammalian counterparts
Rodgers, Anna K. / Lopez, David / Lin, Li / Maden, Malcolm / Scott, Edward W. | 2015
Mechanism of FLT3 ligand dependent resistance to FLT3 inhibitors
Chen, Fangli / Ishikawa, Yuichi / Kihara, Rika / Naoe, Tomoki / Kiyoi, Hitoshi | 2015
Overexpression of RUNX1 short isoform plays a pivotal role in the development of myelodysplastic syndromes/myeloproliferative neoplasms
Sakurai, Hiroko / Harada, Yuka / Matsui, Hirotaka / Nakajima, Hideaki / Kitamura, Toshio / Komatsu, Norio / Harada, Hironori | 2015
Functional significance of MPL expression in the human hematopoietic stem cell compartment
Matsuoka, Yoshikazu / Sumide, Keisuke / Kawamura, Hiroshi / Nakatsuka, Ryusuke / Sasaki, Yutaka / Sonoda, Yoshiaki | 2015
Development of an ex vivo bone marrow mimicry microenvironment in a novel 3D hollow fibre bioreactor
Allenby, Mark C. / Tahlawi, Asma / dos Santos, Susana Brito / Misener, Ruth / Hwang, Yu-Shik / Panoskaltsis, Nicki / Mantalaris, Athanasios | 2015
HSC transplantation in an immunocompetent host without radiation or chemotherapy
Chhabra, Akanksha / Ring, Aaron / Weiskopf, Kipp / Schnorr, Peter John / Gordon, Sydney / Le, Alan C. / Kwon, Hye-Sook / Guo, Nan / Volkmer, Jens / Ho, Po Yi et al. | 2015
Quantification and visualization of dietary iron utilization under erythropoietic stimulation by using stable iron isotope 57FE and mass spectrometry
Matsuo-Tezuka, Yukari / Noguchi-Sasaki, Mariko / Sasaki, Yusuke / Kondo, Kumiko / Kihara, Makoto / Kurasawa, Mitsue / Yorozu, Keigo / Shimonaka, Yasushi | 2015
Extracellular matrix protein Matn4 regulates HSC stress response
Uckelmann, Hannah / Blaszkiewicz, Sandra / Essers, Marieke | 2015
Exploring the role of kit ligand at the onset of hematopoiesis
Azzoni, Emanuele / Nerlov, Claus / De Bruijn, Marella | 2015
Delayed addition of epoetin beta during storage: Effect on peripheral erythrocyte division
Niimi, Gen | 2015
Local and systemic signaling in maintenance of hematopoietic progenitors
Banerjee, Utpal | 2015
Role of bone marrow microenvironment in myeloid leukemia progression
Kumar, Atul / Bhattacharyya, Jina / Jaganathan, Bithiah G. | 2015
Reprogramming adult mesenchymal stem cells into functional hematopoietic stem cells through transdetermination - from molecular mechanism to precise therapy
Yin, Qinwei | 2015
MLL-AF4 perturbs the self-renewal and differentiation potential of HSC during the definitive wave of haematopoiesis: A stage-specific pattern
Malouf, Camille / Kapeni, Chrysa / Ottersbach, Katrin | 2015
A fully validated blood stem/progenitor cell regulatory network reveals mechanisms of cell state stabilisation
Schütte, Judith / Wang, Huange / Jarrett, Andrew / Riepsaame, Joey / Wilson, Nicola / Antoniou, Stella / Calero-Nieto, Fernando / Basilico, Silvia / Kinston, Sarah / Hannah, Rebecca et al. | 2015

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