Mode-of-toxicity prediction for molecular design in the pharmaceutical industry (Englisch)
- Neue Suche nach: Schmidt, Friedemann
- Neue Suche nach: Brennan, Richard
- Neue Suche nach: Czich, Andreas
- Neue Suche nach: Schmidt, Friedemann
- Neue Suche nach: Brennan, Richard
- Neue Suche nach: Czich, Andreas
In:
Toxicology letters
;
280
, 1
;
S69
;
2017
-
ISSN:
- Aufsatz (Zeitschrift) / Print
-
Titel:Mode-of-toxicity prediction for molecular design in the pharmaceutical industry
-
Beteiligte:
-
Erschienen in:Toxicology letters ; 280, 1 ; S69
-
Verlag:
- Neue Suche nach: Elsevier Science B.V., Amsterdam.
-
Erscheinungsdatum:01.01.2017
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Format / Umfang:S69
-
ISSN:
-
Medientyp:Aufsatz (Zeitschrift)
-
Format:Print
-
Sprache:Englisch
- Neue Suche nach: 363.179
- Weitere Informationen zu Dewey Decimal Classification
-
Klassifikation:
DDC: 363.179 -
Datenquelle:
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- S317
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Ursodeoxycholic acid sensitizes human breast adenocarcinoma cells to doxorubicin-induced apoptosisStanimirov, Bojan / Stankov, Karmen / Pavlović, Nebojša / Đanić, Maja / Vasović, Velibor / Mikov, Momir et al. | 2017
- S318
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Optimisation of non-ambulant (clinical) decontamination processesHughes, Philip / Mitchell, Hannah / Adams, Lawrence / Larner, Joanne / Matar, Hazem / Rivers, Samantha / Durrant, Adam / Chilcott, Robert et al. | 2017
- S319
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Toxic responses to polyhexamethylene guanidine phosphate in cytoplasmic organellesBang, In Jae / Jeong, Mi Ho / Yoo, So Hee / Jang, Eun Hye / Kim, Ha Ryong et al. | 2017
- S320
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Papain-cyclodextrin complex: Cytotoxicity and permeability evaluation on Caco-2 cell modelCorazza, Fúlvio Gabriel / Nambu, Felipe Augusto Nery / Leite-Silva, Vania Rodrigues / Andreo-Filho, Newton / Lopes, Patricia Santos et al. | 2017
- S321
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Neuronal cultures coupled to Micro-Electrode Arrays as a new tool for neurotoxicological evaluationCervetto, Chiara / Marcoli, Manuela / Massobrio, Paolo / Farisello, Pasqualina / Novellino, Antonio / Martinoia, Sergio et al. | 2017
- S322
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Proteomic mining and functional annotation of red blood cell proteins in alcohol use disordersBoşgelmez, İ. İpek / Güvendik (emeritus), Gülin / Dilbaz, Nesrin / Esen, Metin et al. | 2017
- S324
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REACH Compliance Project: Alternative methods to animal testing in REACH registrations on high tonnage chemicals – Data waiving and adaptationKronsbein, Anna Lena / Maul, Katrin / Menz, Jakob / Oertel, Angelika / Sittner, Dana / Springer, Andrea / Bernauer, Ulrike / Herbst, Uta / Schulte, Agnes et al. | 2017
- S325
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Levels of ochratoxin A and heavy metals in herbal tea samples commercialized in TurkeyOzden, Hakan / Ozden, Sibel et al. | 2017
- S326
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Author index| 2017
- v
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Contents| 2017
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In-vitro-only testing strategies for cosmetic ingredients: Utility of newly validated genotoxicity assays using human skin and fertilized hen's eggsDesprez, Bertrand / Fautz, Rolf / Hoffmann, Sebastian / Hewitt, Nicola / Fowler, Paul / Reisinger, Kerstin / Kuehnl, Jochen / Ouédraogo, Gladys / Kenny, Julia / Pfuhler, Stefan et al. | 2017
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Organ toxicity attenuation by nanomicelles containing curcuminoids: Comparing the protective effects on tissues oxidative damage induced by DiazinonMohammadi, Hamidreza et al. | 2017
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Cytotoxic properties of lactate ester alkoxylates in relation to various EO/PO-alkoxylation degreesFayyaz, Susann / Lee, Moung Sook / Bauer, Martin / Kreiling, Reinhard et al. | 2017
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Investigating neurotoxicity using pluripotent stem cellsKrause, Karl-Heinz et al. | 2017
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Comparison of toxicity patterns of 19 compounds across 16 organ-specific in vitro test methodsKrebs, Alice et al. | 2017
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Systems toxicology assessment of repeated exposure to cigarette smoke and a potential modified-risk tobacco product aerosol on gingival organotypic culturesZanetti, Filippo / Sewer, Alain / Leroy, Patrice / Majeed, Shoaib / Torres, Laura Ortega / Trivedi, Keyur / Guedj, Emmanuel / Elamin, Ashraf / Frentzel, Stefan / Ivanov, Nikolai V. et al. | 2017
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Impact of high-fat and high-fat-high-fructose diet on vessels and heart in rats with metabolic syndromeKaprinay, Barbara / Lipták, Boris / Sotníková, Ružena / Knezl, Vladimír / Gáspárová, Zdenka et al. | 2017
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Evaluating skin sensitising potential of chemicals with a simple and rapid in vitro methodBuzzella, Alice / Mori, Michela / Vicini, Riccardo / Angelinetta, Claudio / Mazzini, Giuliano / Pastoris, Ornella et al. | 2017
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The microbiome in the activation vs. detoxification of chemical carcinogensSturla, Shana et al. | 2017
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Functional and structural characteristics of two phospholipase A2-derived from Cerastes cerastes venom: Structure–function relationshipChérifi, Fatah / Saoud, Samah / Djebari, Fatima Laraba et al. | 2017
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Effects of Zearalenone on the metabolic pathways and its relation to the epigenetic mechanisms in HepG2 cellsKaraman, Ecem Fatma / Senyildiz, Mine / Zeybel, Mujdat / Ozden, Sibel et al. | 2017
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Biomarkers for uranium risk assessment for the development of a molecular epidemiological protocolGueguen, Yann / Roy, Laurence / Hornhardt, Sabine / Badie, Christophe / Hall, Janet / Baatout, Sarah / Laurent, Olivier / Ebrahimian, Teni / Grison, Stephane / Ibanez, Chrystelle et al. | 2017
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Development of a novel genotoxicity evaluation method using a next-generation sequencer, linking chemical-induced mutations to human cancerMatsumura, Shoji / Honda, Hiroshi / Yamane, Masayuki / Morita, Osamu et al. | 2017
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Evaluation of predictive in silico models for mutagenicity prediction of food and feed ingredientsVuorinen, Anna / Bellion, Phillip / Beilstein, Paul et al. | 2017
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On importance of pathophysiology for an integrative toxicologyNeu, Eva / Michailov, Michael Ch. / Foltin, Viktor / Senn, Tatjana / Welscher, Ursula / Foltinova, Janka / Graw, Jochen / Hofstetter, Alfons / Hohlbrugger, Gero / Madersbacher, Helmut et al. | 2017
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Detection of Aristolochic acid I DNA adducts via UPLC-MS/MS in RPTEC/TERT1 cellsBastek, Heinke / Zubel, Tabea / Maraslis, Michail / Schröder, Julia / Mangerich, Aswin / Beneke, Sascha / Dietrich, Daniel R. et al. | 2017
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Development of a predictive in silico model for mixtures of azole fungicides acting on the skeletal craniofacial AOPBattistoni, Maria / Palazzolo, Luca / Bois, Frederic Yves / Di Renzo, Francesca / Eberini, Ivano / Guerrini, Uliano / Metruccio, Francesca / Moretto, Angelo / Menegola, Elena et al. | 2017
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VIVD: A virtual in vitro distribution model for predicting intra- and sub-cellular concentrations in toxicity assaysFisher, Ciarán / Jamei, Masoud / Gardner, Iain et al. | 2017
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Phenolic endocrine disruptors' concentration levels in hair of Greek pregnant womenKatsikantami, Ioanna / Karzi, Vasiliki / Tzatzarakis, Manolis / Stavroulaki, Athina / Xezonaki, Pelagia / Sifakis, Stavros / Tsatsakis, M. Aristidis / Rizos, Apostolos et al. | 2017
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Dioxin-like POPs induced aryl hydrocarbon receptor transactivity and oxidative stress status in the Danish pregnant women and fetal growth outcomesLong, Manhai / Bonefeld-Jørgensen, Eva Cecilie et al. | 2017
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Predicting neurological targets for chemical neurotoxins using ToxCast in vitro data and read-across within QSAR ToolboxChushak, Yaroslav / Pangburn, Heather / Gearhart, Jeffery M. et al. | 2017
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Worm-on-a-chip: Fully automated whole organism platform for screening and identification of toxicity using the nematode Caenorhabditis elegansMader, Robert / Mouchiroud, Laurent / Cornaglia, Matteo / Gijs, Martin A.M. / Auwerx, Johan et al. | 2017
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Aldehyde oxidase metabolism route inhibition via sodium tungstate in imidacloprid exposed rabbitsVardavas, Alexander / Tzatzarakis, Manolis / Stivaktakis, Polychronis / Fragkiadaki, Persefoni / Alegakis, Athanasios / Tsiaoussis, John / Tsitsimpikou, Christina / Carvalho, Félix / Tsatsakis, Aristidis et al. | 2017
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The combined xenoestrogenic activity of perfluorinated alkyl acids in pregnant women and indices of fetal growthBjerregaard-Olesen, Christian / Bonefeld-Jørgensen, Eva et al. | 2017
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Toxic events induced by the antiepileptic drug carbamazepine: Is bioactivation really involved?Antunes, Alexandra M.M. / Martins, Inês L. / Telo, J. Paulo / Marques, M. Matilde et al. | 2017
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Alginate micro encapsulation modulates the capsaicin cytotoxicity for its prospective use in diabetic neuropathyNegrei, Carolina / Hudita, Ariana / Galateanu, Bianca / Hirjau, Mircea / Burcea, George / Ginghina, Octav / Lupuliasa, Dumitru / Ion, Rodica et al. | 2017
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Measurement of epigallocatechin 3-gallate content in Iranian green tea and its associations with total phenolic compounds and antioxidant levels thereofEbadollahinatanzi, Alireza / Sahneh, Banafsheh Nasiri et al. | 2017
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Antibiotic-induced cytotoxicity and cholestasis are related to an endoplasmic reticulum stress and amplified by inflammatory cytokines in human hepatocytesBurban, Audrey / Sharanek, Ahmad / Guguen-Guillouzo, Christiane / Guillouzo, Andre et al. | 2017
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Toxicity study in C57/BL6 mice after repeated intramuscular administration of the HIV-1 therapeutic prime-boost vaccine combination DNA.HTI and MVA.HTIBrander, Christian / Brennan, Caroline / Guzmán, Antonio / Tortajada, Araceli et al. | 2017
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Assessment of molecular mechanism(s) of styrene toxicity in blood plasma and liverNiaz, Kamal / Maqbool, Faheem / Khan, Fazlullah / Hassan, Fatima Ismail / Baeeri, Maryam / Navaei-Nigjeh, Mona / Hassani, Shokoufeh / Abdollahi, Mohammad et al. | 2017
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Assessment of nanoscale zero-valent iron toxicity towards several bacterial species by specific marker of oxidative stress monitoringSemerád, Jaroslav / Cajthaml, Tomáš et al. | 2017
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Correlations between levels of dioxins and PCBs in environment samples and wild boar musclesWarenik-Bany, Malgorzata / Maszewski, Sebastian / Mikolajczyk, Szczepan / Pietron, Wojciech / Piskorska-Pliszczynska, Jadwiga et al. | 2017
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Inhalation exposure to cigarette smoke induces oxidative stress and inflammation in lung without causing systemic oxidative stress in miceLee, Moo-Yeol / Park, Kwang-Hoon / Park, Jung-Min et al. | 2017
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Toxicity and biological responses (in vitro) influenced by aggregation and agglomeration of manufactured nanomaterialsMurugadoss, Sivakumar / Van Den Brule, Sybille / Sebaihi, Noham / Brassinne, Frederic / Mast, Jan / Godderis, Lode / Lison, Dominique / Hoet, Peter et al. | 2017
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Influence of dietary cypermethrin, vitamin E and selenium on biochemical parameters of the lepidopteran model host Galleria mellonellaCoskun, Mustafa / Kayis, Tamer / Gulsu, Emre / Alp, Emel et al. | 2017
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Using ellagic acid for enhance outcomes of pancreatic islet transplantationRahimifard, Mahban / Niaz, Kamal / Moeini, Shermineh / Baeeri, Maryam / Abdollahi, Mohammad et al. | 2017
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Influence of styrene on plasma parameters and molecular expression of islets of Langerhans in rat modelNiaz, Kamal / Hassan, Fatima Ismail / Maqbool, Faheem / Khan, Falullah / Momtaz, Saeideh / Baeeri, Maryam / Navaei-Nigjeh, Mona / Rahimifard, Mahban / Abdollahi, Mohammad et al. | 2017
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Exposure to glyphosate and glyphosate-based herbicides during the perinatal period affect maternal behavior and maternal brain plasticityDechartres, Julie / Pawluski, Jodi L. / Nmezu, Niece / Renoult, Charlène / Charlier, Thierry D. et al. | 2017
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The importance of understanding physico-chemical properties of chemicals in the evaluation of serious eye damage/eye irritation: Cosmetic Europe analysisPfannenbecker, Uwe / Adriaens, Els / Alépée, Nathalie / Bagley, Daniel / Desprez, Bertrand / Hibatallah, Jalilah / Mewes, Karsten R. / Àlvar, Sala / McNamee, Pauline et al. | 2017
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Treatment with retinoic acid increases severity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced skin lesions in hairless miceRudyak, Stanislav G. / Paltsev, Mikhail A. / Panteleyev, Andrey A. et al. | 2017
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Metabolomics in vitro in kidney cells – A tool for investigation of the nephrotoxicityBirk, Barbara / Sperber, Saskia / Huener, Hans-Albrecht / Verlohner, Andreas / Walk, Tilmann / Haake, Volker / Kamp, Hennicke / van Ravenzwaay, Ben et al. | 2017
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Evaluation of FABP4 as a novel urinary biomarker of drug-induced kidney injury in a preclinical modelObajdin, Jana / Cotter, Mabel / de Ron, Pierrette / Valentin, Jean-Pierre / da Costa, Andre Nogueira / Gryshkova, Vitalina et al. | 2017
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Investigation on the relationship between oxidative stress and cognitive neuropsychology status in patients with MSMalekirad, Ali Akbar / Nikpour, Hakimeh / Faraji, Fardin / Abbasi, Sima et al. | 2017
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Serum alpha-GST activity as an alternative biomarker in olanzapine induced hepatotoxicity under the impact of genetic polymorphism of GSTsElkama, Aylin / Ak, Mehmet / Nemutlu, Emirhan / İlik, Nazlican / Karahalil, Bensu et al. | 2017
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Cosmetics Europe assessment of non-animal approaches for predicting skin sensitizationKlaric, Martina / Alépée, Nathalie / Allen, Dave / Ashikaga, Takao / Casey, Warren / Clouet, Elodie / Cluzel, Magalie / Del Bufalo, Aurelia / Gellatly, Nikki / Goebel, Carsten et al. | 2017
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Genotoxicity evaluation of naringin on mammalian cell lines by micronucleus assayBacanlı, Merve / Anlar, Hatice Gül / Başaran, A. Ahmet / Başaran, Nurşen et al. | 2017
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Use of the benchmark dose approach for 7-hydroxycoumarin 90-day toxicological data analysisZinovieva, Maryna et al. | 2017
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The toxicological interpretation of MOSH and MOAH data and the implications for risk assessmentCarrillo, Juan-Carlos / Danneels, Dirk / Woldhuis, Jan et al. | 2017
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Assessment of systemic exposure to metabolically generated mono- and diethanolamine in rats treated with 2, 2′-(C12-18 alkylimino)-diethanolLee, Moung Sook / Kaling, Moritz / Kreiling, Reinhard et al. | 2017
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Learning from approved kinase inhibitors to better inform on the safety risks of specific kinasesVicart, Axel / Kinyamu-Akunda, Jacqueline / Whitebread, Steven / Dumotier, Berengere / Urban, Laszlo / Kluwe, William / Moggs, Jonathan / Pognan, François / Chibout, Salah-Dine et al. | 2017
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Development of an OECD guidance document on good in vitro method practice (GIVIMP)Coecke, Sandra / Bowe, Gerard / Bostroem, Ann-Charlotte et al. | 2017
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Ambient air pollution in beirut: Attributable cancer risk and mortality burdenDhaini, Hassan / Salameh, Thérèse / Waked, Antoine / Sauvage, Stéphane / Borbon, Agnès / Formenti, Paola / Doussin, Jean-François / Locoge, Nadine / Afif, Charbel et al. | 2017
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Biokinetics of engineered nanoparticles (NPs)Brain, Joseph / Molina, Ramon / Konduru, Nagarjun / Wohlleben, Wendel / Graham, Uschi et al. | 2017
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Characterization and application of iPSCs in drug discovery research. Focus in hepatocytesBertinetti-Lapatki, Cristina et al. | 2017
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Knowing the unknown: Computational methods to manage the boundaries of our knowledge in chemical risk assessmentBoyer, Scott et al. | 2017
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Quantification and relationship of stress and adversity in cellular systemsLimonciel, Alice et al. | 2017
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Membrane remodeling by polycyclic aromatic hydrocarbons and its role in cell death signallingLagadic-gossmann, Dominique et al. | 2017
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Progress in in silico toxicity model development – Lessons learnt analysing complex toxicity dataPastor, Manuel / Sanz, Ferran et al. | 2017
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The IMI eTOX initiative – Data mining, read-across and predictive models for target evaluation and early drug candidate assessmentSteger-Hartmann, Thomas / Pognan, Francois / Sanz, Ferran et al. | 2017
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Extension of the carcinogen dose–response database for threshold of toxicological concernCronin, Mark / Belfield, Samuel / Escher, Sylvia / Firman, James / Lieu, Jie / Marsaux, Cyril / Mostrag-Szlichtyng, Aleksandra / Przybylak, Katarzyna / Rathman, James / Tarkhov, Aleksey et al. | 2017
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Comparative analysis of respiratory, skin and eye irritation potential of chemicals using Japanese GHS classificationOno, Atsushi / Hiraoka, Yumi / Hirose, Akihiko / Jinno, Hideto et al. | 2017
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Results of the project NanoEmission – Effects of bariumsulfate nanoparticles before and after waste incineration processes on human lung cellsThomas, Sarah / Schumann, Berit / Glahn, Felix / Foth, Heidi et al. | 2017
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Transcriptome comparison of air pollutants-induced effects on human keratinocytesNa, Hye-Won / Kim, Kyu Han / Jung, Changjo / Lee, Tae Ryong / Kim, Hyoung-June et al. | 2017
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Exposure to 2, 2′, 4, 4′-tetrabromodiphenyl ether at late gestation changes signaling molecules in murine placentaLeung, Lai / Zhu, Yun et al. | 2017
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Use of ex-vivo testis culture to explore mechanisms of seminiferous tubular atrophy upon PIM inhibitionLarsson, Marie H. / Andersson, Ulf / Harris, Jayne / Hornberg, Jorrit J. / Mitchard, Terri et al. | 2017
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Oxidative damage and energetic crisis in cardiomyocites after co-exposure of cocaine and morphineMartins, Maria João / Moreira, Patricia / Bravo, Rita Roque / Carmo, Helena / Carvalho, Félix / Bastos, Maria de Lourdes / Dinis-Oliveira, Ricardo Jorge / Silva, Diana Dias da et al. | 2017
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Confirmation of the conception of proportionality with the example of a study of migratory-destructive curves for pesticidesRakitskii, Valerii et al. | 2017
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Estimation of exposure dose and operator risk assessment of plant protection products with different dermal absorption defaultYou, Are Sun / Oh, Jin A. / Park, Sujin / Jo, Youmi / Park, Yeon-Ki / Lee, Je Bong et al. | 2017
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Mutagenic activity of mixture of herbicides ethofumesate, phenmedipham, and desmedipham in two strains of laboratory mice: CBA*C57BL/6 and CD-1Rakitskii, Valerii / Ilyushina, Natalia / Masaltsev, Gleb / Averianova, Natalia / Egorova, Olga / Revazova, Julia / Prokofev, Evgenij et al. | 2017
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Comparative study of the impact of CuO NMs and CuSO4 on differentiated Caco-2 intestinal cells and a co-culture mucus secreting Caco-2 modelUde, Victor Chibueze / Stone, Vicki / Johnston, Helinor Jane et al. | 2017
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Impact of silver nanoparticles on photosynthesis in tobacco plantsTkalec, Mirta / Cvjetko, Petra / Biba, Renata / Vrček, Ivana Vinković / Šikić, Sandra / Štefanić, Petra Peharec / Balen, Biljana et al. | 2017
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Do nanoparticles affect the human stem cell differentiation?Komo, Patrizia / Kohl, Yvonne et al. | 2017
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Studying the fetal bovine serum protein corona associated with single and multilayer graphene oxide nanomaterialsFranqui, Lidiane Silva / Borges, Antônio Carlos / Farias, Marcelo Alexandre de / Portugal, Rodrigo Villares / Leme, Adriana Franco Paes / Coluci, Vitor Rafael / Martinez, Diego Stefani Teodoro et al. | 2017
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Polycyclic aromatic hydrocarbons show androgenic and antiandrogenic activity in yeast expressing human androgen receptorStypuła-Trębas, Sylwia / Minta, Maria / Radko, Lidia / Posyniak, Andrzej et al. | 2017
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Hygienic regulation of MCPA (dimethylamine salt) in soilRakitskii, Valerii / Sinitskaya, Tatiana / Gromova, Irina / Tsatsakis, Aristidis et al. | 2017
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Acute toxicity of emamectin benzoate on the brain acetylcholinesterase enzyme (AChE) activity of Oreochromis niloticusKargın, Ferit / Temiz, Özge / Aytekin, Tuzun / Varkal, Hazal Sag / Firidin, Gülbin Gör / Firat, Özgür / Firat, Özge / Cogun, Hikmet Y. et al. | 2017
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DNA damage induced by PM0.5 samples in A549 and BEAS-2B human cell lines: Results of the MAPEC studyBonetta, Silvia / Bonetta, Sara / Feretti, Donatella / Moretti, Massimo / Verani, Marco / De Donno, Antonella / Schilirò, Tiziana / Carraro, Elisabetta / Gelatti, Umberto et al. | 2017
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Influence of the selected nanomaterials and micro-pollutants on the environmentMajerová, Michaela / Chorvátová, Alžbeta Marček / Kromka, Alexander / Mackuľak, Tomáš et al. | 2017
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Discrepancies in genotoxicity testing strategy between chemical and pharmaceutical product regulationsBergeret, Sylvaine / Jacobs, Sandy / Bilau, Maaike et al. | 2017
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Assessing the role of celastrole on cisplatin induced nephrotoxicity under in vitro conditionsBoran, Tugce / Gunaydin, Aysenur / Jannuzzi, Ayse Tarbin / Ozcagli, Eren / Alpertunga, Buket et al. | 2017
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Association of PCBs and DDTs exposure with infertility in Pakistani populationAmir, Saira / Tzatzarakis, Manolis / Eqani, Samas / Nosyrev, Alexander E. / Shah, Syed Tahir Abbas / Tsatsakis, Aristides M. et al. | 2017
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Skin sensitization studies by quantitative structure–toxicity relationships (QSTR) approachSato, Kazuhiro / Ciloy, Jose Martin / Kusaka, Yukinori et al. | 2017
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In silico prediction of the skin sensitisation potential of non-quinonoid Michael acceptors: New reactivity assessments and evidence based precursor selectionPayne, Martin / Ponting, David et al. | 2017
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Determination of JWH-210, JWH-122 and JWH-081 in urine by Liquid Chromatography Mass Spectrometric methodBrajković, Gordana / Jović-Stošić, Jasmina / Đorđević, Snežana / Kilibarda, Vesna / Čurćić, Marijana / Radosavljević-Stevanović, Nataša / Brajković, Zorica / Vučinić, Slavica et al. | 2017
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Use of in silico models for compound property prediction to reduce the in vitro screening burdenAhlberg, Ernst / Bendtsen, Claus / Carlsson, Lars / Fredlund, Linda / Jones, Barry / Noeske, Tobias / Oprisiu, Ioana / Strömstedt, Per-Erik / Wernevik, Johan / Winiwarter, Susanne et al. | 2017
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Paraoxonase 1 (PON1) is a valid plasma marker to detect illicit treatment with dexamethasone in veal calvesMazza, Maria / Pezzolato, Marzia / Guglielmetti, Chiara / Brusadore, Sonia / Botta, Mario / Meistro, Serena / Ingravalle, Francesco / Baioni, Elisa / Bozzetta, Elena / Acutis, Pier Luigi et al. | 2017
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Targeted whole transcriptome gene expression profiling for mechanistic toxicologyVanSteenhouse, Harper / Shepard, Peter / Yeakley, Joanne / Seligmann, Bruce et al. | 2017
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Effects of fumonisin B1 on global DNA methylation in HK-2 CellsBayoglu, Seyda Omerustaoglu / Karaman, Ecem Fatma / Senyildiz, Mine / Ozden, Sibel et al. | 2017
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Development of an innovative bioreactor to simulate cutaneous absorption and metabolism for risk assessment purposesQuantin, Paul / Catoire, Sophie / Ficheux, Herve et al. | 2017
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An assay to characterize the impact of cigarette smoke exposure on mucociliary clearance in-vitroFrentzel, Stefan et al. | 2017
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In vitro anti-proliferative and antimetastatic effects of lupan pentacyclic triterpenesCoricovac, Dorina / Pavel, Ioana Zinuca / Draghici, George Andrei / Pinzaru, Iulia / Avram, Stefana / Mioc, Marius / Ghiulai, Roxana / Soica, Codruta / Dehelean, Cristina Adriana et al. | 2017
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The HET-CAM in vitro assay: An useful tool for vaginal formulations evaluation regarding irritation?de Oliveira, Rita Palmeira / Machado, Rita M. / Martinez-de-Oliveira, José / de Oliveira, Ana Palmeira et al. | 2017
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Highly allergenic proteins regulate pro-inflammatory signaling: Implications for thymic stromal lymphopoietin induction by protein allergensKuroda, Yasutaka / Yuki, Takuo / Takahashi, Yutaka / Sakaguchi, Hitoshi / Matsunaga, Kayoko / Itagaki, Hiroshi et al. | 2017
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Epithelial to mesenchymal transition induced by zinc oxide nanoparticles in A549 cell linePark, Ji Soo / Jeong, Mi Ho et al. | 2017
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Challenges in using markers of neuroinflammation for hazard identificationSandström, Jenny / Zurich, Marie-Gabrielle / Tschudi-Monnet, Florianne et al. | 2017
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How could mechanistic approaches improve risk assessment and advance the 3Rs?Prior, Helen et al. | 2017
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Cytotoxicity of environmental pollutants and implications in atherosclerosisHennig, Bernhard / Petriello, Michael et al. | 2017
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EMF and the redox homeostasis: The link to cell activation processesSimko, Myrtill et al. | 2017
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The importance of information on toxicokinetics for human health risk assessment – Some examplesGeraets, Liesbeth / Zeilmaker, Marco / Bos, Peter et al. | 2017
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Stem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injuryGoldring, Chris et al. | 2017
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An assessment strategy for candidate modified-risk tobacco products (MRTP)Peitsch, Manuel / Smith, Maurice / Clark, Bruce / Luedicke, Frank / Schaller, Jean-Pierre / Vanscheeuwijck, Patrick / Hoeng, Julia et al. | 2017
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Pathway to regulatory submission: The Swedish Match storySolyst, Jim et al. | 2017
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Long-term toxicity carbon nanotubes: Commonality and differencesPoland, Craig / Duffin, Rodger / Murphy, Fiona et al. | 2017
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Setting the scene – The investigative toxicology landscape in the European pharmaceutical industryRoth, Adrian et al. | 2017
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Effect of MLL modified H3K4me3 on aluminum induced cognitive impairmentNiu, Qiao et al. | 2017
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Chemoproteomic approaches for off-target hazard identificationBantscheff, Marcus et al. | 2017
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LincRNA-p21 implication in esophageal squamous cell carcinomaZhang, Ying / Liu, Ran / Pan, Enchun / Pu, Yuepu / Yin, Lihong et al. | 2017
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Investigation of sleep quality in shipyard workers by wearable deviceChuang, Hsiao-Chi / Lai, Ching-Huang / Su, Ting-Yao / Chuang, Kai-Jen / Hsiao, Ta-Chih / Pan, Chih-Hong et al. | 2017
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Unravelling the mechanisms of neuronal, hepatic, cardiac and renal cell toxicity of two synthetic cannabinoids, 5F-PB 22 and XLR-11Santos-Carvalho, Ana / Fontes, Adriana / Santos, Nuno / Araújo, Ana Margarida / Pinho, Paula Guedes de / Cavadas, Claudia / Carvalho, Félix / Ferreira, Sónia et al. | 2017
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Dermal exposure and risk assessmentBisson, Michèle / Kersale, Chloé / Andres, Sandrine / Jaeg, Jean-Philippe et al. | 2017
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Inappropriate medication storage as a potential health risk factor among a Mexican sampleVergara-Castañeda, Arely / Vallejo, Gabriel Fernández / Buendía, Marite Benítez / Zenteno, Daniel Arenas / Martino-Roaro, Laura et al. | 2017
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Influence of cimetidine and experimental diabetes mellitus on gabapentin pharmacokinetics in ratsde Lima Benzi, Jhohann Richard / Yamamoto, Priscila Akemi / Baviera, Amanda Martins / de Moraes, Natalia Valadares et al. | 2017
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Better understanding of bioavailability of cosmetic ingredients: Results from Cosmetics Europe Skin Bioavailability projectSchepky, Andreas / Cubberley, Richard / Duplan, Helene / Eilstein, Joan / Ellison, Corie / Gregoire, Sebastien / Hewitt, Nicky / Jacques-Jamin, Carine / Lange, Daniela / Roe, Amy et al. | 2017
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Genotoxicity assessment of selected plant extractsHeinrich, Miriam / Turek, Claudia / Mörbt, Nora / Vögele, Peter / Stintzing, Florian Conrad et al. | 2017
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Effects of exposure to tembotrione during gestation on serum oestradiol and testosterone levels in neonatal ratsMikolić, Anja / Kašuba, Vilena / Micek, Vedran / Karačonji, Irena Brčić / Želježić, Davor et al. | 2017
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Primary hippocampal neurons as suitable model to evaluate the influence of neurotoxicants on neuronal developmentMarchetti, Natalia / Gerosa, Laura / Boraso, Mariaserena / Viviani, Barbara et al. | 2017
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U937 cell line activation test (U-SENS™): An OECD adopted in vitro skin sensitisation assay addressing the activation of dendritic cellsPiroird, Cécile / Nardelli, Laurent / Cotovio, José / Alépée, Nathalie et al. | 2017
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Effect of bifenthrin on TNF α and interleukin 1β in mice liversNieradko-Iwanicka, Barbara / Nieradko, Agnieszka / Borzęcki, Andrzej et al. | 2017
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In vitro nephrotoxicity of synthetic cannabinoidsSilva, João Pedro / Carmo, Helena / Carvalho, Félix et al. | 2017
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Suppression of FK506 induced nephrotoxicity in mice by Bacopa monnieriiOyuoni, Atif Abdulwahab A. / Saggu, Shalini / Rehman, Hasibur / Toussan, Ehab / Thabiani, Aziz Al et al. | 2017
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Long-term low-dose exposure study of inhaled cerium dioxide – Organ burden quantification and pattern of particle distribution in organsTentschert, Jutta / Laux, Peter / Jungnickel, Harald / Brunner, Josephine / Krause, Benjamin / Estrela-Lopis, Irina / Merker, Carolin / Meijer, Jan / Ernst, Heinrich / Ma-Hock, Lan et al. | 2017
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A high content screening approach to genotoxicity testing: Detection of DNA damage and differentiation of clastogens and aneugens utilising histone biomarkersWalker, Paul / Bauch, Caroline / Purdie, Laura / Dilworth, Clive et al. | 2017
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Assessing the penetration of chemicals into excised human skin by non-invasive confocal Raman microscopyJung, Nathalie / Windbergs, Maike et al. | 2017
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The GARD platform for potency assessment of skin sensitizing chemicalsZeller, Kathrine S. / Forreryd, Andy / Lindberg, Tim / Gradin, Robin / Chawade, Aakash / Lindstedt, Malin et al. | 2017
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3D in vitro cultures of human hepatocyte-like cells as an alternative competent model for nevirapine biotransformation studiesCipriano, Madalena / Pinheiro, Pedro F. / Sequeira, Catarina / Santos, Jorge M. / Oliveira, Nuno G. / Antunes, Alexandra M.M. / Matilde Marques, M. / Rodrigues, Joana S. / Castro, Matilde / Pereira, Sofia A. et al. | 2017
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Incorporation of human relevant metabolism into fit-for-purpose in vitro assays for safety assessment: Case study with bioactivated mutagensClewell, Rebecca / Phillips, Martin / Dunnick, Katie / Balbuena, Pergentino / Yoon, Miyoung et al. | 2017
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Detecting the non-ionizing radiation induced genotoxicity by the Comet assay methodNémeth, Zsuzsanna / Kubinyi, Györgyi / Brech, Annamária / Laczkovich-Szaladják, Erzsébet / Bakos, József / Forgács, Zsolt / Selmaoui, Brahim / Thuróczy, György et al. | 2017
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A drug discovery perspective on the microbiomeBrown, James et al. | 2017
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Hazard identification in novel antimicrobials assessed by methods in vitroKejlová, Kristina / Bendová, Hana / Sosnovcová, Jitka / Chrz, Jan / Dvořáková, Markéta / Krsek, Daniel / Kolářová, Hana / Vlková, Alena / Očadlíková, Danuše et al. | 2017
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Searching for an alternative to BALB/3T3 cells to develop an effective method for simultaneous phototoxic and photogenotoxic screening systemZgadzaj, Anna / Czacharowska, Zuzanna / Figat, Ramona / Nałecz-Jawecki, Grzegorz et al. | 2017
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Plasma ochratoxin A in the European brown bear (Ursus arctos L.) from CroatiaRašić, Dubravka / Lazarus, Maja / Huber, Đuro / Reljić, Slaven / Peraica, Maja et al. | 2017
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Counter-propagation artificial neural network models in read-across predictions of toxicityDrgan, Viktor / Župerl, Špela / Venko, Katja / Vračko, Marjan / Novič, Marjana et al. | 2017
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Supporting data-mining, read-across and chemical space analysis for toxicity data gap filling using the COSMOS databaseSchwab, Christof / Yang, Chihae / Rathman, James / Mostrag-Szlichtyng, Aleksandra / Tarkhov, Aleksey / Liu, Jie / Madden, Judith / Bassan, Arianna / Fioravanzo, Elena / Cronin, Mark et al. | 2017
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PLETHEM – An interactive open-source platform for bridging the source-to-outcome continuumPendse, Salil / Clewell, Rebecca / Efremenko, Alina / McMullen, Patrick / Yoon, Miyoung / Clewell, Harvey et al. | 2017
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Elevated levels of DDTs and PCBs in head hair of infertile people from PakistanAmir, Saira / Tzatzarakis, Manolis / Qamar, Raheel / Vakonaki, Elena / Tsatsakis, Aristides M. / Shah, Syed Tahir Abbas et al. | 2017
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Classification and labelling of human health and environmental hazards for chemicals: Keeping a global perspectiveTerry, Claire / Aggarwal, Manoj / Juberg, Daland et al. | 2017
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The study of cytotoxic activity of new berberine derivatives on cancer and non-cancer cell linesŠvédová, Alexandra / Milata, Viktor / Jantová, Soňa et al. | 2017
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Cholestatic drugs induce preferential accumulation of toxic bile acids in human HepaRG cellsSharanek, Ahmad / Burban, Audrey / Humbert, Lydie / Guguen-Guillouzo, Christiane / Rainteau, Dominique / Guillouzo, Andre et al. | 2017
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Effects of levamisole, a cocaine adulterant, on adrenergic response in the rabbit renal arteryGuerra, Solanye / Marchio, Patricia / Gimeno, Marc / Aldasoro, Martin / Valles, Soraya Lilian / Jorda, Adrian / Aldasoro, Constanza / Mauricio, Maria Dolores / Vila, Jose Maria et al. | 2017
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Immunological biomarkers of effect of organophosphorus compounds possessing a delayed neurotoxic actionFedchenko, Olena / Zhminko, Peter / Prodanchuk, Mykola et al. | 2017
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Protective role of St. John's Wort on formaldehyde-induced lung tissue injury: Inhibiton of inflammation and oxidative stress mediated apoptosisBeceren, Ayfer / Aydemir, Sezgin / Ozakpinar, Ozlem Bingol / Sehirli, Ahmet Ozer / Omurtag, Gulden Zehra et al. | 2017
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Bisphenols are not inherently estrogenicBarton, Charles / Maier, Mark / Mallen, Thomas et al. | 2017
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Impact of cigarette smoke, next generation tobacco and nicotine products on the cytotoxic, oxidative and pro-inflammatory status of THP-1 cellsBrunssen, Coy / Giebe, Sindy / Hofmann, Anja / Brux, Melanie / Hewitt, Katherine / Lowe, Frazer / Morawietz, Henning et al. | 2017
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Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirementsMelbourne, Jodie / Sharma, Monita / Allen, David / Clippinger, Amy et al. | 2017
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Developmental neurotoxicity: Sex differences in toxic effects and toxic effects on sex differencesLevin, Edward et al. | 2017
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High-throughput microfluidic platform for culture of 3D-kidney tissue modelsVormann, Marianne / Lanz, Henriëtte / van Vught, Remko / Gijzen, Linda / Trietsch, Sebastiaan / Joore, Jos / Vulto, Paul et al. | 2017
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A 90-days inhalation toxicity study of multi-walled carbon nanotubes (MWCNTs) in Fisher 344 ratsLee, Sang Sik / Sung, Jae Hyuck et al. | 2017
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Online Integrated Testing Strategy (ITS) for quantitative skin sensitization potency assessment using Bayesian networks and accounting for bioavailabilitySayed, Ahmed Abdelaziz / Brajnik, Maja / Bachler, Daniel / Exner, Thomas / Hardy, Barry et al. | 2017
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Modulatory role of Ociumum basilicum (Al-Rehan) leaves against 4-tert-octyl phenol induced oxidative stress in ratsRehman, Hasibur / Saggu, Shalini / Oyuoni, Atif Abdulwahab A. / Thibiani, Aziz Al et al. | 2017
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Potency ranking of dermal sensitizing chemicals using the IVSA and epiCS® skin tissuesDeGeorge, George / Pratt, Lisa / Troese, Matthew / Weisensee, Dirk / Engelking, Oliver et al. | 2017
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The h-CLAT for assessment of dermal sensitization potency of the OECD Proficiency chemicals and of commercially available mixturesBurgos, Diana / Carathers, Micheal / Varsho, Bennett / Vij, Puneet / DeGeorge, George et al. | 2017
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Benzo[a]pyrene-induced DNA damage associated with mutagenesis in primary human activated T lymphocytesLiamin, Marie / Boutet-Robinet, Elisa / Jamin, Emilien L. / Fernier, Morgane / Khoury, Laure / Kopp, Benjamin / Le Ferrec, Eric / Vignard, Julien / Audebert, Marc / Sparfel, Lydie et al. | 2017
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Role of in silico tools and text mining in the safety assessment of selected plant coumarinsRaitano, Giuseppa / Benfenati, Emilio / Ananiadou, Sophia / Fu, Xiao / Do, Quoc Tuan / Rat, Patrice / Sousselier, Laurent et al. | 2017
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Known carcinogenic promoters of the liver and skin do not indicate cell proliferation activity in digestive system in 28-days repeated dose toxicity study in ratsHonda, Hiroshi / Kawamoto, Taisuke / Imai, Norio / Ito, Yuichi / Morita, Osamu et al. | 2017
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Risk assessment of benzophenone-8 in cosmetic productsKim, Min-Kook / Lim, Seong-Kwang / Suh, Hyo-Sun / Kim, Min-Hwa / Baek, Seol-Hwa / Lee, Byung-Mu et al. | 2017
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Study of the functions of lincRNA-ROR in human esophageal squamous cell carcinoma (ESCC)Shang, Muhe / Liu, Ran et al. | 2017
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Integrating genetics, epigenomics and transcriptomics to elucidate mechanisms of xenobiotic-induced non-genotoxic carcinogenesisMoggs, Jonathan / Espinola, Alberto Del Rio / Vitobello, Antonio / Terranova, Remi et al. | 2017
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Understanding the limitations of, and improving, read-across predictions for repeated-dose toxicity by learning from case studiesEnoch, Steve / Cronin, Mark / Schultz, Terry et al. | 2017
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Tobacco harm reduction and e-cigarettesPolosa, Riccardo et al. | 2017
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Common good practices in biomarker development in toxicology and ecotoxicologyBelpoggi, Fiorella / Budnik, Lygia Therese et al. | 2017
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Oxidative stress and feto-maternal well-being in pregnancyCooke, Marcus / Konje, Justin / Potdar, Neelam et al. | 2017
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TIPARP and ADP-ribosylation negatively regulate AHR activityMatthews, Jason et al. | 2017
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Measurement of 8-oxo-7, 8-dihydro-2′-deoxyguanosine in urine by an improved ELISARossner, Pavel / Orhan, Hilmi / Koppen, Gudrun / Sakai, Kazuo / Santella, Regina M. / Ambroz, Antonin / Rossnerova, Andrea / Sram, Radim J. / Ciganek, Miroslav / Neca, Jiri et al. | 2017
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Applying 3D-systems to toxicological assessment: Bridging academic research and industry needsSuter-Dick, Laura et al. | 2017
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Implementation of toxicokinetics in toxicity studies – Example of 4-methylanisolevan Kesteren, Petra / Brandon, Esther / Piersma, Aldert / Bos, Peter et al. | 2017
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Opioid education programs and nasal naloxone rescue kits in EuropeSkulberg, Arne Kristian / Dale, Ola / Tylleskar, Ida et al. | 2017
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Human stem cell research for potential drug-induced cardiac arrhythmias and neuronal side effects: Janssen's strategyLu, Hua Rong / Kopljar, Ivan / Mohamed, Kreir / Teisman, Ard / Gallacher, David J. et al. | 2017
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In vitro phototoxicity testing and human health risk assessments for agrochemicalsAggarwal, Manoj / Corvaro, Marco / Morriss, Alistair / Mehta, Jyotigna et al. | 2017
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Towards establishing criteria and best practices for analysing omic data for regulatory decision makingTong, Weida et al. | 2017
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EUROTOX 2017 Organizing Committee| 2017
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Dysbiosis in chronic intestinal inflammation and tumorigenesis: Can we apply Koch's postulates?Haller, Dirk et al. | 2017
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Towards establishing a consistent set of criteria to assess the use of non-animal methods in regulatory decision makingBoobis, Alan / Parish, Stan / Wolf, Douglas et al. | 2017
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Development of a high content assay in ciPTEC-OAT1 as an in vitro model to predict drug-induced nephrotoxicitySjogren, Anna-Karin / Breitholtz, Katarina / Forsgard, Malin / Milton, Lucas / Stahl, Simone / Fenner, Katherine / Wilmer, Martijn / Persson, Mikael / Hornberg, Jorrit et al. | 2017
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CON4EI: EpiOcular eye irritation tests – OECD TG 492 and ET-50 (time-to-toxicity) protocolsKandarova, Helena / Letasiova, Silvia / Adriaens, Els / Drzewiecka, Agnieszka / Fochtman, Przemyslaw / Guest, Robert / Willoughby, Jamin A. / Alépée, Nathalie / Verstraelen, Sandra / Van Rompay, An et al. | 2017
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Extended OECD 422 screening study for the evaluation of substances with suspected reproductive toxicity and/or endocrine activitySegal, Lawrence / Canut, Lourdes / Myers, David / García, Silvia / Blee, Mark / Butala, John et al. | 2017
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Assessment of oxidative stress inducing effects of perfluorooctanoic acid in mice testes and possible preventive effect of taurineEndirlik, Burcu Ünlü / Eken, Ayşe / Öztürk, Figen / Gürbay, Aylin et al. | 2017
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Acetyl-l-carnitine attenuates arsenic-induced neurotoxicity through suppression of oxidative damages and inflammatory responses: A possible mechanism for neuroprotective effectsKeshavarz-Bahaghighat, Hedieh / Sepand, Mohammad Reza / Sabzevari, Omid / Sanadgol, Nima et al. | 2017
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Adverse effects of roundup, a glyphosate herbicide, on reproductive hormone system and antioxidant enzymes of tilapia, Oreochromis niloticusKocamaz, Derya / Kaya, Askın Barış / Oruc, Elif et al. | 2017
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Effects of potassium titanate on the pneumonia in respiratory syncytial virus-infected miceHashiguchi, Seiko / Akashi, Toshi / Hirose, Akihiko / Miyauchi, Aki / Yoshida, Hiroki / Kurokawa, Masahiko / Watanabe, Wataru et al. | 2017
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Effects of multi-walled carbon nanotubes on primary immunity responding to respiratory syncytial virus infection in miceWatanabe, Wataru / Hashiguchi, Seiko / Akashi, Toshi / Hirose, Akihiko / Yoshida, Hiroki / Miyauchi, Aki / Sugita, Chihiro / Kurokawa, Masahiko et al. | 2017
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Size-segregated urban particulate matter characterization by electron microscopy and dynamic light scattering during the sample preparationMarvanová, Soňa / Kulich, Pavel / Skoupý, Radim / Hubatka, František / Ciganek, Miroslav / Bendl, Jan / Hovorka, Jan / Machala, Miroslav et al. | 2017
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Role of surface capping on the cytotoxicity of silica nanoparticles in rat alveolar epithelial cellsBrandão, Fátima / Bessa, Maria João / Costa, Carla / Fraga, Sónia / Haase, Andrea / Teixeira, João Paulo et al. | 2017
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Acute non-accidental carbon monoxide poisoningKiat, Wenceslao et al. | 2017
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Mitochondrial involvement in the mechanism of oxidative damage induced by graphene and graphene oxide at the skin levelPelin, Marco / Fusco, Laura / Sosa, Silvio / Martìn, Cristina / Vazquez, Ester / Prato, Maurizio / Tubaro, Aurelia et al. | 2017
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Genomic responses of human lung cells exposure through a successful in vitro field deployment in Houston, TexasNguyen, Hang / Sexton, Kenneth / Smeester, Lisa / Aagaard, Kjersti Marie / Shope, Cynthia Do / Lefer, Barry / Flynn, James / Alvarez, Sergio / Erickson, Mathew / Fry, Rebecca et al. | 2017
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Chemical analysis, mutagenic and antimutagenic effects of Cynara scolymus L. plant partsGuzelmeric, Etil / Helvacioglu, Sinem / Hamitoglu, Muhammed / Aydin, Ahmet / Yesilada, Erdem et al. | 2017
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Alcohol and toxicological findings in drowning cases in Crete, GreeceKanaki, Katerina / Mantakas, Xenofontas / Nathena, Despoina / Kontogiannis, Andreas / Vakonaki, Elena / Renieri, Elisavet / Christakis-Hampsas, Maria / Tzanakakis, George / Tzatzarakis, Manolis / Tsatsakis, Aristides et al. | 2017
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Valdecoxib recovers the lipid composition, order and dynamics in colon cancer cell lines independent of COX-2 expressionGenç, Aysun Inan / Gok, Seher / Banerjee, Sreeparna / Severcan, Feride et al. | 2017
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Effect of polymorphism of CYP2C8 on hydroxylation of diclofenac acyl-glucuronideLazarska, Katarzyna Ewa / Commandeur, Jan N.M. / Vermeulen, Nico P.E. et al. | 2017
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Immunological safety evaluation in Göttingen minipigs: The CONFIRM initiativeDescotes, Jacques / Allais, Linda / Ancian, Philippe / Pedersen, Henrik Duelund / Friry-Santini, Claire / Iglesias, Antonio / Rubic, Tina / Skaggs, Hollie / Vestbjerg, Peter et al. | 2017
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Predicting in silico the Direct-Peptide-Reactivity-Assay (DPRA) within the Allergic Contact Dermatitis frameworkDetroyer, Ann / Piroird, C. / Eilstein, J. / Imbert, S. / Ivanova, H. / Popova, I. / Kuseva, C. / Karakolev, Y. / Dimitrov, S. / Mekenyan, Ovanes et al. | 2017
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Development of an ECHA structured database on repeated dose toxicityCeriani, Lidia / Bassan, Arianna / Gissi, Andrea / Ciacci, Andrea / Fotakis, George / Baldin, Rossella / Kovarich, Simona / Pavan, Manuela / Fioravanzo, Elena et al. | 2017
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A mass spectrometric platform for the quantitation of sulfur mustard-induced nucleic acid damageZubel, Tabea / Kurzeja, Sabrine / Burckhardt-Boer, Waltraut / Kindrat, Jennifer / Schmidt, Annette / Steinritz, Dirk / John, Harald / Thiermann, Horst / Mangerich, Aswin / Bürkle, Alexander et al. | 2017
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Host-associated microbiota is required for neurobehavioral development in zebrafish and is targeted by environmental chemicalsTal, Tamara / Phelps, Drake / Brinkman, Nichole / Keely, Scott / Anneken, Emily / Hunter, Deborah / Gearhart, Alexander / Betancourt, Doris / Wood, Charles et al. | 2017
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Identification of structure-specific hepatotoxic potential of different pyrrolizidine alkaloids using Random Forest and artificial Neural NetworkSchöning, Verena / Hammann, Felix / Drewe, Jürgen et al. | 2017
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Accurate and reproducible dispensing of patterned picoliter quantities of tobacco extract onto apical surfaces of human 3D reconstructed airway tissuesBehrsing, Holger / Hilger, Norah / Huang, Song / Constant, Samuel et al. | 2017
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Natural toxins: Poisoning of domestic animal in Italy – 2016 annual reportCaloni, Francesca / Cortinovis, Cristina / Rivolta, Marina / Davanzo, Franca et al. | 2017
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Five years after deadly poisoning: How methanol changed lives of 50 people. Lessons from the Czech mass poisoning outbreak in 2012Zacharov, Sergej et al. | 2017
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Bo Holmstedt Memorial Fund (BHMF) Lecture human skin stem cell-derived hepatic cells and their potential applicationsRogiers, Vera et al. | 2017
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Application of the ToxTracker reporter assay in a mode of action approach for genetic toxicology assessmentHendriks, Giel / Derr, Remco / Racz, Peter / Zeijdel, Lisette / Vrieling, Harry et al. | 2017
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The bull spermatozoon is a suitable cell type for toxicity assessmentEskov, Andrey / Sokolov, Anatoly et al. | 2017
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Foetal Calf Serum-free media and serum alternativesvan der Valk, Jan / Kolar, Roman / Gstraunthaler, Gerhard et al. | 2017
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Expression of immune-related molecules in THP-1 macrophage-like cells exposed to nanoparticlesBrzicova, Tana / Javorkova, Eliska / Vrbova, Kristyna / Zajicova, Alena / Holan, Vladimir / Sikorova, Jitka / Klema, Jiri / Topinka, Jan / Rossner, Pavel et al. | 2017
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Maleic acid induces oxidative stress in rats after single and repeated administrationChiang, Su-yin / Wu, Charlene / Chen, Hsin-Chang / Chen, Shu-Ting / Chang, Bau-Suei / Wu, Kuen-Yuh et al. | 2017
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The effect of fluoride toxicity on plasma enzymes of Oreochromis niloticusÇoğun, Hikmet Yeter / Aytekin, Tuzun / Temiz, Özge / Varkal, Hazal Sağ / Firidin, Gülbin Gök / Firat, Özgür / Firat, Özge / Kargın, Ferit et al. | 2017
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Evaluation of incision wound healing activity of Scorzonera veratrifolia in Wistar albino ratsGecim, Mert / Beceren, Ayfer / Aydemir, Sezgin / Sardas, Semra et al. | 2017
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A novel three-dimensional model for long-term evaluation of drug toxicity in vitroRashidi, Hassan / Hay, David et al. | 2017
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The application of toxicokinetics in an animal-free risk assessmentFabian, Eric / Haase, Christian / Gomes, Caroline / Birk, Barbara / Ramirez, Tzutzuy / Zbranek, Rene / van Ravenzwaay, Bennard / Landsiedel, Robert et al. | 2017
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State-of-the-art of the assessment of ADME using multiple organs on a chipMaschmeyer, Ilka / Lorenz, Alexandra / Bauer, Sophie / Ramme, Anja / Rings, Thamée / Kuehnl, Jochen / Marx, Uwe et al. | 2017
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How do you know that material is what it says it is? DNA barcoding for the taxonomic identification of fungiOberlies, Nicholas et al. | 2017
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Long-term inhalation study with CeO2- and BaSO4 nanomaterials – Study design, in-life findings, and lung burdenMa-Hock, Lan / Groeters, Sibylle / Strauss, Volker / Keller, Jana / Wiench, Karin / van Ravenzwaay, Bennard / Landsiedel, Robert et al. | 2017
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Non-clinical and clinical assessment of an e-cigarette productProctor, Christopher / Gaca, Marianna / Lowe, Frazer / Minet, Emmanuel / Fiebelkorn, Stacy / Prasad, Krishna / Camacho, Oscar / Fearon, Ian / Liu, Chuan / Wright, Christopher et al. | 2017
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Dopamine: Neuropsychiatric disorders and neurotoxicityAli, Syed / Pereira, Frederico et al. | 2017
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Regulatory needs for the assessment of respiratory sensitisation under REACH and CLPBroeckaert, Fabrice / Rossi, Laura H. et al. | 2017
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The antioxidant, anti-inflammatory and antidiabetic activities of Sternbergia lutea ssp. lutea and Sternbergia lutea ssp. siculaIscan, Gulcin Saltan / Sarialtin, Sezen Yilmaz / Yazgan, Aysenur / Yilmaz, Betul Sever / Agca, Asli Can / Coban, Tulay et al. | 2017
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Comparison of routine clinical pathology parameters in Wistar Han rats at different agesWang, Zhimei / McPherson, Sue et al. | 2017
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Investigation of boron mediated reproductive and developmental effects in highly boron exposed populationDuydu, Yalcin / Basaran, Nursen / Aydın, Sevtap / Üstündag, Aylin / Göktaş, Hatica Gül / Yalcin, Can Özgür / Bacanlı, Merve / Sarigöl, Zehra / Aydos, Kaan / Atabekoglu, Cem Somer et al. | 2017
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The UK Committee on Toxicity: Review of chemicals in the diets of infants and children aged 1 to 5 yearsPotter, Claire / Hill, Frances / Acheampong, Rufina / Buckley, Lily / Cemeli, Eduardo / Chandler, Tim / Hedley, Douglas / Kurzawa-Zegota, Maggie / Sbaiti, Azmi / Shavila, Joe et al. | 2017
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Assessment of serum oxidative stress biomarkers for smoking patients in different age groupsUngurianu, Anca / Margină, Denisa / Grădinaru, Daniela et al. | 2017
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Risk assessment of isoamyl p-Methoxycinnamate in cosmetic productsKim, Min-Hwa / Lim, Seong-Gwang / Kim, Min-Kook / Suh, Hyo-Sun / Baek, Seol-Hwa / Lee, Byung-Mu et al. | 2017
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NEOGENE Project – Genetic and epigenetic effects of in utero exposure to tobacco smoke. Rationale and designCosta, Carla / Reis, Ana Teresa / Silva, Ana Inês / Tirsina, Alla / Barros, Sérgio / Barbosa, Fernando / Teixeira, João Paulo et al. | 2017
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A comprehensive in vitro model to evaluate hepatotoxicity and determine potential mechanismsDas, Sonali / Khanna, Amit / Rajendran, Karthik / Thota, Balaram / Venkatareddy, Balamurali / Raman, Divya / Rajagopalan, Vishal / Dharwar, Nivedita / Priyadarsini, Sukanya / Ponnusamy, Kalaiselvan et al. | 2017
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Effect of maternal depression and venlafaxine treatment on the neurobehavioral development of the juvenile and adolescent rat offspringBögi, Eszter / Belovičová, Kristína / Mach, Mojmír / Ujhazy, Eduard / Dubovicky, Michal et al. | 2017
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Identifying potential liver toxicants using in vitro and in silico methods in a weight-of-evidence based approachMadden, Judith / Pletz, Julia / Webb, Steven / Enoch, Steven / Cronin, Mark et al. | 2017
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Renal toxicity biomarker analysis upon compound exposures in a kidney-on-a-chipWilmer, Martijn / Vriend, Jelle / Nieskens, Tom / Lanz, Henriëtte / Vormann, Marianne / Gijzen, Linda / Ramp, Daniella / Suter-Dick, Laura / Masereeuw, Roos / Vulto, Paul et al. | 2017
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Exposure to cigarette smoke and aerosol from the potential reduced risk product THS2.2 on A/J mice in life-time inhalation studyVeljkovic, Emilija / Wong, Ee Tsin / Luettich, Karsta / Guedj, Emmanuel / Dulize, Remi / Nury, Catherine / Titz, Bjorn / Leroy, Patrice / Vuillaume, Grégory / Elamin, Ashraf et al. | 2017
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Behaviorally active environmental chemicals target genes of cell-autonomous control of neural progenitors and interneuron development in hippocampus. Possible microRNA involvementLichtensteiger, Walter / Bassetti-Gaille, Catherine / Rehrauer, Hubert / Kühn-Georgijevic, Jelena / Tresguerres, Jesus A.F. / Schlumpf, Margret et al. | 2017
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Molecular effects of rotenone exposure and wash-out in an in vitro 3D dopaminergic cell modelHarris, Georgina / Eschment, Melanie / Hogberg, Helena / Pamies, David / Freeman, Dana / Hartung, Thomas / Smirnova, Lena et al. | 2017
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Conduct of the OECD 438 ICE test using eyes from a different age of chickens and model BQ900 slit-lampGuest, Robert / Henzell, Gary / Frosdick, Ian et al. | 2017
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Butyrate plays a supporting role in alterations of lipidome induced by DHA in colon cancer cellsTylichova, Zuzana / Slavík, Josef / Cigánek, Miroslav / Ovesná, Petra / Krčmář, Pavel / Straková, Nicol / Machala, Miroslav / Kozubík, Alois / Vondráček, Jan / Hofmanová, Jiřina et al. | 2017
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Evaluation of circulating cell free DNA as biomarker of pesticide exposureCayir, Akin / Coskun, Mahmut et al. | 2017
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Markers of oxidative stress are elevated in exhaled breath condensate of workers in nanocomposites productionPelclova, Daniela / Zdimal, Vladimir / Dvorackova, Stepanka / Komarc, Martin / Vlckova, Stepanka / Fenclova, Zdenka / Schwarz, Jaroslav / Ondracek, Jakub / Makes, Otakar / Kacer, Petr et al. | 2017
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Accumulation of copper oxide nanoparticles in gill, liver and muscle tissues of Clarias gariepinusDuran, Servet / Tuncsoy, Mustafa / Ay, Ozcan / Cicik, Bedii / Erdem, Cahit et al. | 2017
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Application of microbial population analysis as ecotoxicity tests in situCajthaml, Tomáš et al. | 2017
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Frequency of sterigmatocystin (STC) and 5-methoxysterigmatocystin (5-MET-STC)-producing airborne Aspergilli from flooded and unflooded area in CroatiaDespot, Daniela Jakšić / Sertić, Miranda / Turk, Ana Mornar / Kifer, Domagoj / Nigović, Biljana / Klarić, Maja Šegvić et al. | 2017
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Protective effect of Dendropanax morbifera on the diabetes-induced renal damageRicha, Sachan / Kim, Ji Young / Kim, Hyung Sik et al. | 2017
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Alcohol and drugs in suicidal etiology autopsies performed in the Atacama region – Chile, 2007–2016Espinoza, Carlos Modesto / Araneda, Enzo Cristian / Silva, Carlos Alberto / Novakovic, Iván Martín / Flores, David Rigoberto et al. | 2017
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Suitability of in vivo and in vitro models for assessing on the safety of natural and industrial productsMerinas-Amo, Tania / Bellido-Pedraza, Carmen María / García-Zorrilla, Victoria / Velasco-Ruíz, Alejandro / Merinas-Amo, Rocío / Chladek, Ladislav / Pineda, Teresa / Font, Rafael / Del Río-Celestino, Mercedes / Kokoska, Ladislav et al. | 2017
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Simulating human skin wounds – Perspectives on non-animal alternatives for bio-relevant testing of pharmaceuticalsPlanz, Viktoria / Windbergs, Maike et al. | 2017
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Contribution of mouse carcinogenicity study for safety assessment of pesticide approved in JapanMorita, Takeshi / Toda, Moiu / Inoue, Kaou et al. | 2017
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Disease-modifying effects of allergen-nanoparticle conjugates – A study in human alveolar co-culture models mimicking the type 2 pre-inflamed stateMills-Goodlet, Robert / Geppert, Mark / Himly, Martin / Duschl, Albert et al. | 2017