Synthesis and antimicrobial activity of some novel hydrazide, benzochromenone, dihydropyridine, pyrrole, thiazole and thiophene derivatives (Englisch)
- Neue Suche nach: Refat, H. M.
- Neue Suche nach: Fadda, A. A.
- Neue Suche nach: Refat, H. M.
- Neue Suche nach: Fadda, A. A.
In:
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
;
72
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419-426
;
2014
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ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:Synthesis and antimicrobial activity of some novel hydrazide, benzochromenone, dihydropyridine, pyrrole, thiazole and thiophene derivatives
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Beteiligte:Refat, H. M. ( Autor:in ) / Fadda, A. A. ( Autor:in )
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Erschienen in:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ; 72 ; 419-426
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Verlag:
- Neue Suche nach: Elsevier Science B.V., Amsterdam.
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Erscheinungsdatum:01.01.2014
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Format / Umfang:8 pages
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ISSN:
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Medientyp:Aufsatz (Zeitschrift)
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Format:Print
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Sprache:Englisch
- Neue Suche nach: 615.1
- Weitere Informationen zu Dewey Decimal Classification
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Klassifikation:
DDC: 615.1 -
Datenquelle:
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Platinated benzonaphthyridone is a stronger inhibitor of poly(ADP-ribose) polymerase-1 and a more potent anticancer agent than is the parent inhibitorWang, B. / Qian, H. / Yiu, S. M. / Sun, J. / Zhu, G. et al. | 2014
- 372
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Novel camphane-based anti-tuberculosis agents with nanomolar activityStavrakov, G. / Valcheva, V. / Philipova, I. / Doytchinova, I. et al. | 2014
- 374
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Development and biological evaluation of ^9^9^mTc-sulfonamide derivatives for in vivo visualization of CA IX as surrogate tumor hypoxia markersAkurathi, V. / Dubois, L. / Celen, S. / Lieuwes, N. G. / Chitneni, S. K. / Cleynhens, B. J. / Innocenti, A. / Supuran, C. T. / Verbruggen, A. M. / Lambin, P. et al. | 2014
- 380
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Aziridines from alkenyl-@b-D-galactopyranoside derivatives: Stereoselective synthesis and in vitro selective anticancer activityVega-Perez, J. M. / Palo-Nieto, C. / Vega-Holm, M. / Gongora-Vargas, P. / Calderon-Montano, J. M. / Burgos-Moron, E. / Lopez-Lazaro, M. / Iglesias-Guerra, F. et al. | 2014
- 393
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Novel toll-like receptor 4 (TLR4) antagonists identified by structure- and ligand-based virtual screeningSvajger, U. / Brus, B. / Turk, S. / Sova, M. / Hodnik, V. / Anderluh, G. / Gobec, S. et al. | 2014
- 400
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Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines as thymidine phosphorylase inhibitorsSun, L. / Li, J. / Bera, H. / Dolzhenko, A. V. / Chiu, G. N. C. / Chui, W. K. et al. | 2014
- 411
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Synthesis of 1,3-thiazine-2,4-diones with potential anticancer activityFerreira, M. / Assuncao, L. S. / Filippin-Monteiro, F. B. / Creczynski-Pasa, T. B. / Sa, M. M. et al. | 2014
- 419
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Synthesis and antimicrobial activity of some novel hydrazide, benzochromenone, dihydropyridine, pyrrole, thiazole and thiophene derivativesRefat, H. M. / Fadda, A. A. et al. | 2014
- 427
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Synthesis, biological evaluation and molecular docking studies of flavone and isoflavone derivatives as a novel class of KSP (kinesin spindle protein) inhibitorsDong, J. J. / Li, Q. S. / Liu, Z. P. / Wang, S. F. / Zhao, M. Y. / Yang, Y. H. / Wang, X. M. / Zhu, H. L. et al. | 2014
- 434
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Synthesis and radiopharmacological evaluation of ^6^4Cu-labeled bombesin analogs featuring a bis(2-pyridylmethyl)-1,4,7-triazacyclononane chelatorBergmann, R. / Ruffani, A. / Graham, B. / Spiccia, L. / Steinbach, J. / Pietzsch, J. / Stephan, H. et al. | 2014
- 447
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Synthesis, structure-activity relationship and biological evaluation of 2,4,5-trisubstituted pyrimidine CDK inhibitors as potential anti-tumour agentsShao, H. / Shi, S. / Foley, D. W. / Lam, F. / Abbas, A. Y. / Liu, X. / Huang, S. / Jiang, X. / Baharin, N. / Fischer, P. M. et al. | 2014
- 456
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Novel water-soluble prodrugs of acyclovir cleavable by the dipeptidyl-peptidase IV (DPP IV/CD26) enzymeDiez-Torrubia, A. / Cabrera, S. / de Castro, S. / Garcia-Aparicio, C. / Mulder, G. / De Meester, I. / Camarasa, M. J. / Balzarini, J. / Velazquez, S. et al. | 2014
- 469
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Design, synthesis and molecular modelling studies of novel 3-acetamido-4-methyl benzoic acid derivatives as inhibitors of protein tyrosine phosphatase 1BRakse, M. / Karthikeyan, C. / Deora, G. S. / Moorthy, N. S. H. N. / Rathore, V. / Rawat, A. K. / Srivastava, A. K. / Trivedi, P. et al. | 2014
- 477
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Novel isatin-based hydroxamic acids as histone deacetylase inhibitors and antitumor agentsNam, N. H. / Huong, T. L. / Mai Dung, D. T. / Phuong Dung, P. T. / Kim Oanh, D. T. / Quyen, D. / Thao, L. T. / Park, S. H. / Kim, K. R. / Han, B. W. et al. | 2014
- 487
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Solution-phase microwave assisted parallel synthesis of N,N'-disubstituted thioureas derived from benzoic acid: Biological evaluation and molecular docking studiesRauf, M. K. / Talib, A. / Badshah, A. / Zaib, S. / Shoaib, K. / Shahid, M. / Florke, U. / Imtiaz-ud-Din / Iqbal, J. et al. | 2014
- 497
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Design, synthesis and structure-activity relationship of novel Relacin analogs as inhibitors of Rel proteinsWexselblatt, E. / Kaspy, I. / Glaser, G. / Katzhendler, J. / Yavin, E. et al. | 2014
- 505
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@a- and @b-hydrazino acid-based pseudopeptides inhibit the chymotrypsin-like activity of the eukaryotic 20S proteasomeBordessa, A. / Keita, M. / Marechal, X. / Formicola, L. / Lagarde, N. / Rodrigo, J. / Bernadat, G. / Bauvais, C. / Soulier, J. L. / Dufau, L. et al. | 2014
- 525
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8-(2-Furyl)adenine derivatives as A"2"A adenosine receptor ligandsDal Ben, D. / Buccioni, M. / Lambertucci, C. / Thomas, A. / Klotz, K. N. / Federico, S. / Cacciari, B. / Spalluto, G. / Volpini, R. et al. | 2014
- 536
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Design, diversity-oriented synthesis and structure activity relationship studies of quinolinyl heterocycles as antimycobacterial agentsRachakonda, V. / Alla, M. / Kotipalli, S. S. / Ummani, R. et al. | 2014
- 548
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Synthesis and biological evaluation of novel ferrocene-naphthoquinones as antiplasmodial agentsGarcia-Barrantes, P. M. / Lamoureux, G. V. / Perez, A. L. / Garcia-Sanchez, R. N. / Martinez, A. R. / San Feliciano, A. et al. | 2014
- 558
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Improved synthesis and in vitro evaluation of the cytotoxic profile of oxysterols oxidized at C4 (4@a- and 4@b-hydroxycholesterol) and C7 (7-ketocholesterol, 7@a- and 7@b-hydroxycholesterol) on cells of the central nervous systemNury, T. / Samadi, M. / Zarrouk, A. / Riedinger, J. M. / Lizard, G. et al. | 2014
- 568
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Synthesis and antiproliferative activity of @a-branched @a,@b-unsaturated ketonesKarpaviciene, I. / Cikotiene, I. / Padron, J. M. et al. | 2014
- 579
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Synthesis of novel 1,2,3-triazole based benzoxazolinones: Their TNF-@a based molecular docking with in-vivo anti-inflammatory, antinociceptive activities and ulcerogenic risk evaluationHaider, S. / Alam, M. S. / Hamid, H. / Shafi, S. / Nargotra, A. / Mahajan, P. / Nazreen, S. / Kalle, A. M. / Kharbanda, C. / Ali, Y. et al. | 2014
- 589
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Co(II) and Cu(II) pyrophosphate complexes have selectivity and potency against Mycobacteria including Mycobacterium tuberculosisHoffman, A. E. / DeStefano, M. / Shoen, C. / Gopinath, K. / Warner, D. F. / Cynamon, M. / Doyle, R. P. et al. | 2014
- 594
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Indole diterpene alkaloids as novel inhibitors of the Wnt/@b-catenin pathway in breast cancer cellsSallam, A. A. / Ayoub, N. M. / Foudah, A. I. / Gissendanner, C. R. / Meyer, S. A. / El Sayed, K. A. et al. | 2014
- 607
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Skeletal hybridization and PfRIO-2 kinase modeling for synthesis of @a-pyrone analogs as anti-malarial agentParveen, A. / Chakraborty, A. / Konreddy, A. K. / Chakravarty, H. / Sharon, A. / Trivedi, V. / Bal, C. et al. | 2014
- 613
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Advances in the studies of roles of Rho/Rho-kinase in diseases and the development of its inhibitorsGuan, R. / Xu, X. / Chen, M. / Hu, H. / Ge, H. / Wen, S. / Zhou, S. / Pi, R. et al. | 2014
- 623
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Novel coumarin-3-carboxamides bearing N-benzylpiperidine moiety as potent acetylcholinesterase inhibitorsAsadipour, A. / Alipour, M. / Jafari, M. / Khoobi, M. / Emami, S. / Nadri, H. / Sakhteman, A. / Moradi, A. / Sheibani, V. / Homayouni Moghadam, F. et al. | 2014
- 631
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Design, synthesis and evaluation of a cellular stable and detectable biotinylated fumagillin probe and investigation of cell permeability of fumagillin and its analogs to endothelial and cancer cellsZhou, G. C. / Liu, F. / Wan, J. / Wang, J. / Wang, D. / Wei, P. / Ouyang, P. et al. | 2014
- 640
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Copper(II/I) complexes of 5-pyridin-2-yl-[1,3]dioxolo[4,5-g]isoquinoline: Synthesis, crystal structure, antitumor activity and DNA interactionHuang, K. B. / Chen, Z. F. / Liu, Y. C. / Wang, M. / Wei, J. H. / Xie, X. L. / Zhang, J. L. / Hu, K. / Liang, H. et al. | 2014
- 649
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An efficient approach to novel 17-5'-(1',2',4')-oxadiazolyl androstenes via the cyclodehydration of cytotoxic O-steroidacylamidoximes, and an evaluation of their inhibitory action on 17@a-hydroxylase/C"1"7","2"0-lyaseKovacs, D. / Wolfling, J. / Szabo, N. / Szecsi, M. / Kovacs, I. / Zupko, I. / Frank, E. et al. | 2014
- 661
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Identification by in silico and in vitro screenings of small organic molecules acting as reversible inhibitors of kallikreinsTan, X. / Bertonati, C. / Qin, L. / Furio, L. / El Amri, C. / Hovnanian, A. / Reboud-Ravaux, M. / Villoutreix, B. O. et al. | 2014
- 669
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Synthesis, ex vivo and in silico studies of 3-cyano-2-pyridone derivatives with vasorelaxant activityHernandez, F. / Sanchez, A. / Rendon-Vallejo, P. / Millan-Pacheco, C. / Alcaraz, Y. / Delgado, F. / Vazquez, M. A. / Estrada-Soto, S. et al. | 2014
- 677
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Overman rearrangement and Pomeranz-Fritsch reaction for the synthesis of benzoazepinoisoquinolones to discover novel antitumor agentsLi, B. / Wang, G. / Yang, M. / Xu, Z. / Zeng, B. / Wang, H. / Shen, J. / Chen, K. / Zhu, W. et al. | 2014
- 685
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Identification of sulfonic acids as efficient ecto-5'-nucleotidase inhibitorsIqbal, J. / Saeed, A. / Raza, R. / Matin, A. / Hameed, A. / Furtmann, N. / Lecka, J. / Sevigny, J. / Bajorath, J. et al. | 2014
- 692
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Synthesis and biological evaluation of 3-(trimethoxyphenyl)-2(3H)-thiazole thiones as combretastatin analogsBanimustafa, M. / Kheirollahi, A. / Safavi, M. / Kabudanian Ardestani, S. / Aryapour, H. / Foroumadi, A. / Emami, S. et al. | 2014
- 703
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The synthesis, antiviral, cytostatic and cytotoxic evaluation of a new series of acyclonucleotide analogues with a 1,2,3-triazole linkerGlowacka, I. E. / Balzarini, J. / Wroblewski, A. E. et al. | 2014
- 723
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Fine molecular tuning at position 4 of 2H-chromen-2-one derivatives in the search of potent and selective monoamine oxidase B inhibitorsPisani, L. / Catto, M. / Nicolotti, O. / Grossi, G. / Di Braccio, M. / Soto-Otero, R. / Mendez-Alvarez, E. / Stefanachi, A. / Gadaleta, D. / Carotti, A. et al. | 2014
- 740
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Synthesis of some new pyrazole-based 1,3-thiazoles and 1,3,4-thiadiazoles as anticancer agentsDawood, K. M. / Eldebss, T. M. A. / El-Zahabi, H. S. A. / Yousef, M. H. / Metz, P. et al. | 2014
- 750
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Synthesis, biological evaluation and docking studies of 4-aryloxymethyl coumarins derived from substructures and degradation products of vancomycinRevankar, H. M. / Kulkarni, M. V. / Joshi, S. D. / More, U. A. et al. | 2014
- 758
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Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-onesDeng, X. / Elkins, J. M. / Zhang, J. / Yang, Q. / Erazo, T. / Gomez, N. / Choi, H. G. / Wang, J. / Dzamko, N. / Lee, J. D. et al. | 2014
- 768
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Synthesis and biological evaluation of ^1^8F-labeled fluoropropyl tryptophan analogs as potential PET probes for tumor imagingChiotellis, A. / Mu, L. / Muller, A. / Selivanova, S. V. / Keller, C. / Schibli, R. / Kramer, S. D. / Ametamey, S. M. et al. | 2014
- 781
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Unraveling phosphodiesterase surfaces. Identification of phosphodiesterase 7 allosteric modulation cavitiesRedondo, M. / Soteras, I. / Brea, J. / Gonzalez-Garcia, A. / Cadavid, M. I. / Loza, M. I. / Martinez, A. / Gil, C. / Campillo, N. E. et al. | 2014
- 789
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New aminopyrimidine derivatives as inhibitors of the TAM familyTraore, T. / Cavagnino, A. / Saettel, N. / Radvanyi, F. / Piguel, S. / Bernard-Pierrot, I. / Stoven, V. / Legraverend, M. et al. | 2014
- 802
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Synthesis and evaluation of new coumarin-pyridine hybrids with promising anti-osteoporotic activitiesSashidhara, K. V. / Modukuri, R. K. / Choudhary, D. / Bhaskara Rao, K. / Kumar, M. / Khedgikar, V. / Trivedi, R. et al. | 2014
- 811
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Design and synthesis of potent and selective P2X"3 receptor antagonists derived from PPADS as potential pain modulatorsCho, J. H. / Jung, K. Y. / Jung, Y. / Kim, M. H. / Ko, H. / Park, C. S. / Kim, Y. C. et al. | 2014
- 831
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Comparison of Multiple Linear Regressions and Neural Networks based QSAR models for the design of new antitubercular compoundsVentura, C. / Latino, D. A. R. S. / Martins, F. et al. | 2014
- 846
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Synthesis, physicochemical characterization, cytotoxicity, antimicrobial, anti-inflammatory and psychotropic activity of new N-[1,3-(benzo)thiazol-2-yl]-@w-[3,4-dihydroisoquinolin-2(1H)-yl]alkanamidesZablotskaya, A. / Segal, I. / Geronikaki, A. / Eremkina, T. / Belyakov, S. / Petrova, M. / Shestakova, I. / Zvejniece, L. / Nikolajeva, V. et al. | 2014
- 857
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Azetidinone-retinoid hybrids: Synthesis and differentiative effectsPori, M. / Galletti, P. / Soldati, R. / Calza, L. / Mangano, C. / Giacomini, D. et al. | 2014
- 864
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Synthesis, antiproliferative and apoptosis-inducing activity of thiazolo[5,4-d]pyrimidinesSingh, B. / Guru, S. K. / Kour, S. / Jain, S. K. / Sharma, R. / Sharma, P. R. / Singh, S. K. / Bhushan, S. / Bharate, S. B. / Vishwakarma, R. A. et al. | 2014
- 875
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Further optimization of plakortin pharmacophore: Structurally simple 4-oxymethyl-1,2-dioxanes with promising antimalarial activityPersico, M. / Parapini, S. / Chianese, G. / Fattorusso, C. / Lombardo, M. / Petrizza, L. / Quintavalla, A. / Rondinelli, F. / Basilico, N. / Taramelli, D. et al. | 2014
- 887
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Designing and synthesis of novel antimicrobial heterocyclic analogs of fatty acidsAhmad, A. / Varshney, H. / Rauf, A. / Rehan, M. / Subbarao, N. / Khan, A. U. et al. | 2014
- iii
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Graphical contents list| 2014
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Editorial board| 2014