Monitoring in Metastatic Breast Cancer: Is Imaging Outdated in the Era of Circulating Tumor Cells? (Englisch)

In: Breast Care ;  9 ,  1 ;  16-21 ;  2014

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Summary

In clinical practice imaging technologies such as computed tomography (CT), positron emission tomography (PET)/CT and magnetic resonance imaging (MRI) are well-established methods for monitoring metastatic breast cancer (MBC) patients and for assessing therapeutic efficacy. However, several weeks of treatment are required before these technologies can offer any reliable information on effective disease regression, and, in the meanwhile, the patients are exposed to potentially unnecessary therapy. Circulating tumor cells (CTCs) have been shown to be powerful prognostic and predictive markers and provide clinicians with valuable information. However, in one clinical trial, an early change of chemotherapy based on CTC detection did not result in improved survival. Currently, CTC detection outside clinical trials should be limited to selected clinical situations, i.e. increased treatment toxicity or as risk estimation.

© 2014 S. Karger GmbH, Freiburg

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1
Editorial Board
| 2014
2
Contents · Inhalt
| 2014
5
Cutting-Edge Therapy Concepts - Cure Metastatic Breast Cancer?
Thomssen, Christoph / Harbeck, Nadia | 2014
7
Oligometastatic Breast Cancer: A Shift from Palliative to Potentially Curative Treatment?
Di Lascio, Simona / Pagani, Olivia | 2014
16
Monitoring in Metastatic Breast Cancer: Is Imaging Outdated in the Era of Circulating Tumor Cells?
Alunni-Fabbroni, Marianna / Müller, Volkmar / Fehm, Tanja / Janni, Wolfgang / Rack, Brigitte | 2014
23
Primary Metastatic Breast Cancer: The Impact of Locoregional Therapy
Hartmann, Steffi / Reimer, Toralf / Gerber, Bernd / Stachs, Angrit | 2014
29
Psychological Impact of Male Breast Disorders: Literature Review and Survey Results
Kipling, Mike / Ralph, Jane E.M. / Callanan, Keith | 2014
35
Adjuvant Tamoxifen Influences the Lipid Profile in Breast Cancer Patients
Lin, Che / Chen, Li-Sheng / Kuo, Shou-Jen / Chen, Dar-Ren | 2014
41
Prediction of Resection Weight in Reduction Mammaplasty Based on Anthropometric Measurements
Kececi, Yavuz / Sir, Emin | 2014
46
Cardiac Tolerability of Concurrent Administration of Trastuzumab and Anthracycline-Based Regimen as Adjuvant Chemotherapy for Breast Cancer
Watanabe, Naoki / Otsuka, Shoko / Sasaki, Yoko / Shimojima, Reiko / Wani, Yoji / Uchino, Kaori | 2014
52
Second International Consensus Conference on Advanced Breast Cancer (ABC2), Lisbon, 11/09/2013: The German Perspective
Harbeck, Nadia / Marschner, Norbert / Untch, Michael / Decker, Thomas / Hegewisch-Becker, Susanna / Jackisch, Christian / Huober, Jens / Lück, Hans-Joachim / von Minckwitz, Gunter / Scharl, Anton et al. | 2014
60
Online Survey of Patients with Breast Cancer on Complementary and Alternative Medicine
Huebner, Jutta / Muenstedt, Karsten / Prott, Franz J. / Stoll, Christoph / Micke, Oliver / Buentzel, Jens / Muecke, Ralph / Senf, Bianca / on behalf of PRIO (Working group Prevention and Integrative Oncology - German Cancer Society) | 2014
65
Inherent Bias? Patients Who Use the Internet to Find Information on CAM
Baum, Michael | 2014
66
News from the San Antonio Breast Cancer Symposium 2013
Fink, Daniel | 2014
69
Reports of Oncological Societies
| 2014
71
PharmaForum
| 2014
72
Imprint
| 2014
74
PharmaNews / PharmaTicker
| 2014
77
Meetings and Conferences
| 2014
79
Guidelines for Author
| 2014
80
Contents of Forthcoming Issues · Themenvorschau
| 2014

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