Seite 1 von 719 Ergebnissen

Sortieren nach: Relevanz | Aktualität | Titel

Synonyme wurden verwendet für: BACE1

Suche ohne Synonyme: keywords:(BACE1)

Verwendete Synonyme:

  • asp2
  • b site of app cleaving enzyme
  • bace
  • beta secretase 1
  • beta sekretase
  • beta site alzheimer's amyloid precursor protein cleaving enzyme 1
  • beta site app cleaving enzyme 1
  • cas 158736 49 3
  • ec 3 4 23 46
  • flj90568
  • hspc104
  • kiaa1149
  • memapsin 2
  • membrane associated aspartic protease 2
  1.  

    High cholesterol‐induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice

    Thirumangalakudi, Lakshmi / Prakasam, Annamalai / Zhang, Ran et al. | Wiley | 2008
    Schlagwörter: betasite APP cleaving enzyme 1
  2.  

    The novel β‐secretase inhibitor KMI‐429 reduces amyloid β peptide production in amyloid precursor protein transgenic and wild‐type mice

    Asai, Masashi / Hattori, Chinatsu / Iwata, Nobuhisa et al. | Wiley | 2006
    Schlagwörter: betasite APP cleaving enzyme 1
  3.  

    β‐Secretase inhibitor GRL‐8234 rescues age‐related cognitive decline in APP transgenic mice

    Chang, Wan‐Pin / Huang, Xiangping / Downs, Deborah et al. | Wiley | 2011
    Schlagwörter: memapsin 2
  4.  

    pH‐dependent conformational dynamics of beta‐secretase 1: A molecular dynamics study

    Mermelstein, Daniel J. / McCammon, J. Andrew / Walker, Ross C. | Wiley | 2019
    Schlagwörter: betasecretase 1
  5.  

    QSAR and Molecular Modeling Studies on a Series of Pyrrolidine Analogs Acting as BACE-1 Inhibitors

    Arya, Richa / Gupta, Satya Prakash / Paliwal, Sarvesh et al. | Bentham Science Publishers | 2019
    Schlagwörter: Beta-secretase 1 (BACE-1) inhibitors, beta-site APP cleaving enzyme 1
  6.  

    Identification of thyrotropin-releasing hormone as hippocampal glutaminyl cyclase substrate in neurons and reactive astrocytes

    Waniek, Alexander / Hartlage-Rübsamen, Maike / Höfling, Corinna et al. | Elsevier | 2014
    Schlagwörter: BACE1, beta-site APP-cleaving enzyme 1
  7.  

    Structure-based design of cycloamide–urethane-derived novel inhibitors of human brain memapsin 2 (β-secretase)

    Ghosh, Arun K. / Devasamudram, Thippeswamy / Hong, Lin et al. | Elsevier | 2004
    Schlagwörter: Memapsin 2
  8.  

    Potent memapsin 2 (β-secretase) inhibitors: Design, synthesis, protein-ligand X-ray structure, and in vivo evaluation

    Ghosh, Arun K. / Kumaragurubaran, Nagaswamy / Hong, Lin et al. | Elsevier | 2007
    Schlagwörter: Memapsin 2
  9.  

    Novel peptidomimetics as BACE-1 inhibitors: Synthesis, molecular modeling, and biological studies

    Butini, Stefania / Gabellieri, Emanuele / Brindisi, Margherita et al. | Elsevier | 2012
    Schlagwörter: BACE-1, Memapsin 2
  10.  

    Structure-based design, synthesis and biological evaluation of novel β-secretase inhibitors containing a pyrazole or thiazole moiety as the P3 ligand

    Ghosh, Arun K. / Brindisi, Margherita / Yen, Yu-Chen et al. | Elsevier | 2014
    Schlagwörter: Memapsin 2, BACE-1
  11.  

    Structure-based design, synthesis, and biological evaluation of dihydroquinazoline-derived potent β-secretase inhibitors

    Ghosh, Arun K. / Pandey, Satyendra / Gangarajula, Sudhakar et al. | Elsevier | 2012
    Schlagwörter: Memapsin 2
  12.  

    Developing β‐secretase inhibitors for treatment of Alzheimer’s disease

    Ghosh, Arun K. / Brindisi, Margherita / Tang, Jordan | Wiley | 2011
    Schlagwörter: BACE 1, memapsin 2
  13.  

    Late age increase in soluble amyloid-beta levels in the APP23 mouse model despite steady-state levels of amyloid-beta-producing proteins

    Janssen, Leen / Keppens, Cleo / De Deyn, Peter P. et al. | Elsevier | 2015
    Schlagwörter: BACE1, beta-site APP-cleaving enzyme 1
  14.  

    The E1 copper binding domain of full-length amyloid precursor protein mitigates copper-induced growth inhibition in brain metastatic prostate cancer DU145 cells

    Gough, Mallory / Blanthorn-Hazell, Sophee / Delury, Craig et al. | Elsevier | 2014
    Schlagwörter: BACE1, beta-site APP-cleaving enzyme 1
  15.  

    Prospects of β‐Secretase Inhibitors for the Treatment of Alzheimer’s Disease

    Ghosh, Arun K. / Tang, Jordan | Wiley | 2015
    Schlagwörter: BACE1, memapsin2
  16.  

    Structure–activity relationship study of BACE1 inhibitors possessing a chelidonic or 2,6-pyridinedicarboxylic scaffold at the P2 position

    Hamada, Yoshio / Suzuki, Kenji / Nakanishi, Tomoya et al. | Elsevier | 2013
    Schlagwörter: BACE1, BACE1 inhibitor
  17.  

    Macrocyclic BACE inhibitors: Optimization of a micromolar hit to nanomolar leads

    Huang, Yifang / Strobel, Eric D. / Ho, Chih Y. et al. | Elsevier | 2010
    Schlagwörter: BACE, BACE inhibitors
  18.  

    Novel BACE1 inhibitors possessing a 5-nitroisophthalic scaffold at the P2 position

    Hamada, Yoshio / Nakanishi, Tomoya / Suzuki, Kenji et al. | Elsevier | 2012
    Schlagwörter: BACE1, BACE1 inhibitor
  19.  

    Tripeptidic BACE1 inhibitors devised by in-silico conformational structure-based design

    Hamada, Yoshio / Tagad, Harichandra D. / Nishimura, Yoshinori et al. | Elsevier | 2011
    Schlagwörter: BACE1, BACE1 inhibitor

Ergebnisse anzeigen: 10 | 20 | 50