Structural Dynamics and Energetics Underlying Allosteric Inactivation of a GPCR: Insights Gained from Site-Directed Fluorescence Labeling (SDFL) Studies of the Cannabinoid Receptor CB1 (English)
- New search for: Fay, J.
- New search for: Farrens, D. L.
- New search for: Fay, J.
- New search for: Farrens, D. L.
In:
BIOPHYSICAL JOURNAL
;
108
, 2
;
415a
;
2015
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ISSN:
- Article (Journal) / Print
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Title:Structural Dynamics and Energetics Underlying Allosteric Inactivation of a GPCR: Insights Gained from Site-Directed Fluorescence Labeling (SDFL) Studies of the Cannabinoid Receptor CB1
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Contributors:Fay, J. ( author ) / Farrens, D. L. ( author )
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Published in:BIOPHYSICAL JOURNAL ; 108, 2 ; 415a
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Publisher:
- New search for: Elsevier Science B.V., Amsterdam
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Publication date:2015-01-01
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Size:415a
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ISSN:
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
- New search for: 571.4
- Further information on Dewey Decimal Classification
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Classification:
DDC: 571.4 -
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© Metadata Copyright the British Library Board and other contributors. All rights reserved.
Table of contents – Volume 108, Issue 2
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1a
-
Probing Membrane Protein Sequestration and Oligomerization in Polymer-Tethered Phospholipid Bilayers Containing Raft-Mimicking Lipid MixturesNaumann, C. et al. | 2015
- 2
-
Protein Crowding Modulates the Shape and Content of Curved Membranes and Coated VesiclesStachowiak, Jeanne et al. | 2015
- 3
-
Musings at MID-Career: What is so Special about omega-3 Fatty Acids?Feller, Scott et al. | 2015
- 3
-
Translocator Protein in Mitochondrial Cholesterol Transport and the Pharmacology of SteroidogenesisPapadopoulos, Vassilios et al. | 2015
- 3
-
Voltage Dependent Anion Channels (VDAC) and Regulation of Mitochondrial MetabolismLemasters, John J et al. | 2015
- 3
-
High Resolution Crystal Structures of Translocator Protein 18 kDa (TSPO) Reveal Ligand Binding Sites and Effects of a Human Single PolymorphismLi, Fei et al. | 2015
- 3a
-
Bending, Twisting, Popping: Protein and Nucleic-Acid Remodeling by ATP-Dependent Machines and SwitchesBerger, J. et al. | 2015
- 4
-
High-Resolution Mapping of Intracellular Fluctuations using Carbon NanotubesFakhri, Nikta et al. | 2015
- 4
-
Direct Observation of Structure-Function Relationships in Nucleic Acid Processing EnzymesChemla, Yann et al. | 2015
- 4
-
Stiffness Sensing through Myosin II MinifilamentsSchwarz, Ulrich S et al. | 2015
- 4
-
Adaptative Response of Cell Cytoskeleton Rheology and Ordering Governs Matrix Rigidity SensingGupta, Mukund et al. | 2015
- 4a
-
Molecular Mechanisms of Contractility-Based Cellular MechanosensingRobinson, D. N. et al. | 2015
- 5
-
Intrinsic Disorder, Epigenetics, and Leukemia - the MLL-AF9 SAGALokken, Alyson et al. | 2015
- 5
-
Investigation of the EnvZ/OmpR Bacterial Signaling System using Single Particle Tracking and Single Molecule Force SpectroscopyHwee Foo, Yong et al. | 2015
- 5
-
Decoding Protein Plasticity from Single Molecules to Large ComplexesLemke, Edward A et al. | 2015
- 6
-
Ultrastable AFM: Improved Stability, Precision, and Bandwidth for Bio-AFMPerkins, Thomas T et al. | 2015
- 7
-
Revealing Structure and Dynamics of Telomere Maintenance Proteins on DNA: One Molecule at a TimeWang, Hong et al. | 2015
- 7a
-
Fluorescence Nanoscopy by Polarization Modulation (SPoD) and Polarization Angle Narrowing (ExPAN)Walla, P. J. / Hafi, N. / Matthias, G. / Jess, L. S. / Aspelmeier, T. / Martha, Z. / Pfennig, D. / Korte, M. / Munk, A. et al. | 2015
- 8
-
Structural Determinants of TRPV Channel Activation and ModulationGaudet, Rachelle et al. | 2015
- 8
-
Allosteric Mutant Phenotypes Investigated on an α1 Glycine Receptor Transmembrane StructureCorringer, Pierre-Jean et al. | 2015
- 9
-
Hair Cell Ribbon Synapse Function - Differently Optimized for Hearing and BalanceYu, Zhou et al. | 2015
- 10
-
Complexin-Mediated Inhibition of Vesicle Fusion: Conserved Functions from Worm to MouseDittman, Jeremy et al. | 2015
- 10
-
Known Unknowns in ExocytosisHolz, Ronald W et al. | 2015
- 11
-
Single-Molecule Studies of the ER Calcium Sensor STIM1Lewis, Richard et al. | 2015
- 11a
-
Mechanisms and Mechanosensitivity: Exceptional Cadherins for Hearing and BalanceSotomayor, M. et al. | 2015
- 12
-
Role of Desolvation in Thermodynamics and Kinetics of Ligand Binding to a ProteinMondal, Jagannath et al. | 2015
- 12
-
Navigating a Maze - Sensing and Responding to Mechanical Obstacles during Cellular Invasive GrowthPackirisamy, Muthukumaran et al. | 2015
- 12
-
Mechanical Forces in B cell ActivationTolar, Pavel et al. | 2015
- 12a
-
Pharmacophore Modeling using Site-Identification by Ligand Competitive Saturation (SILCS) Method with Multiple Probe MoleculesYu, W. / Raman, E. P. / Lakkaraju, S. K. / Fang, L. / MacKerell, A. D. et al. | 2015
- 13
-
Computational Prediction of G-Quadruplex FormationKreig, Alex et al. | 2015
- 13
-
Computational Design of Repeat-Proteins with a Predefined GeometryAkke, Mikael et al. | 2015
- 13a
-
Protein and RNA Structure Prediction by Integration of Co-Evolutionary Information into Molecular SimulationDe Leonardis, E. / Lutz, B. / Cocco, S. / Monasson, R. / Szurmant, H. / Weigt, M. / Schug, A. et al. | 2015
- 14
-
Binding Competition Studied with Single Molecule FRET: The Integron Recombinase Outcompetes the Single-Stranded DNA Binding Protein for its Recombination SiteGrieb, M. Svea et al. | 2015
- 14
-
RNA Unwinding by the Helicase Mtr4p and the TRAMP Complex Investigated via High-Resolution Optical TrappingPatrick, Eric M et al. | 2015
- 14
-
Structural Ensembles of Intrinsically Disordered Proteins using Molecular Dynamics SimulationRauscher, Sarah et al. | 2015
- 14
-
Heterochromatin Assembly and Dynamics on the Single Molecule LevelKilic, Sinan et al. | 2015
- 14
-
Single-Molecule FRET for Dynamic Structural Biology: DNA Polymerase i Structure and Mechanism with Angstrom PrecisionSustarsic, Marko et al. | 2015
- 15
-
Chromosome Reorganization by the Highly Cooperative Dps ProteinDocter, Margreet et al. | 2015
- 15
-
Asymmetric Nucleosome Disassembly with Disrupted Histones Revealed by Time Resolved Small Angle X-Ray Scattering with Contrast VariationChen, Yujie et al. | 2015
- 15a
-
Role of Interfaces in Peptide Folding and AggregationGanesan, S. J. / Matysiak, S. et al. | 2015
- 16
-
Structural insight into the Phosphoinositide-Regulated Cellular Dynamics of Alpha-ActininGhisleni, Andrea et al. | 2015
- 16
-
Determining How Many Ionic Interactions are Needed for the High Stability of Single Alpha Helical (SAH) DomainsWolny, Marcin D et al. | 2015
- 16
-
Effect of Molecular Crowding on the Structure and Dynamics of Human Apo and Holo Transferrin using 2D-IR Correlation SpectroscopyHaris, Parvez I et al. | 2015
- 17
-
Differentiation of Plasma Membrane Composition and Physical PropertiesLevental, Ilya et al. | 2015
- 17
-
Oxidation Increases the Strength of the Methionine-Aromatic InteractionMcCarthy, Megan R et al. | 2015
- 17
-
NMR Evidence for Unusual Bifurcated Hydrogen Bonding in the TXXH Alpha-Helix N-capping MotifAksel, Tural et al. | 2015
- 17a
-
Real-Time Imaging of Nanoscopic Lipid Domains using iSCATde Wit, G. / Danial, J. S. / Kukura, P. / Wallace, M. I. et al. | 2015
- 18
-
How GM1 Affects the Phase State and Mechanical Properties of Phospholipid MembranesFricke, Nico et al. | 2015
- 18
-
A Fundamental Force that Regulates Nano-Clustering of Proteins in Biological MembranesMandadapu, Kranthi Kiran et al. | 2015
- 18a
-
Orientational Texture of Membrane Domains: Effect of Lipid Composition and Binding of a Bacterial ToxinSimonsen, A. C. / Dreier, J. / Solovyeva, V. / Jeppesen, J. C. / Brewer, J. et al. | 2015
- 19
-
Affinity Calculations for Lipophilic Modulators Binding to Isolated Sites on GABA(A) ReceptorsMurlidaran, Sruthi et al. | 2015
- 19
-
Potentiation of CFTR Gating by an Energetically Additive MechanismYeh, Han-I et al. | 2015
- 19a
-
SLC6A14 Modifies Fluid Secretory Capacity of Cystic Fibrosis Affected Epithelium by Enhancing CFTR Channel FunctionAhmadi, S. / Luk, C. / Xia, S. / Di Paola, M. / Chung, T. / Rommens, J. / Bear, C. et al. | 2015
- 20
-
Expression and Contributions of TRPM7 and KCa2.3/SK3 Channels to the Increased Migration and Invasion of Microglia in Anti-Inflammatory Activation StatesSchlichter, Lyanne et al. | 2015
- 20
-
Positive KCa Channel Gating Modulators with Selectivity for KCa3.1Brown, Brandon M et al. | 2015
- 20
-
Enhanced Activation of an Amino-Terminally Truncated Isoform of Voltage-Gated Proton Channel HVCN1 Enriched in Malignant B cellsHondares, Elayne et al. | 2015
- 20a
-
Atomic Basis for Potassium Channel Potentiation by A Novel Class of Anti-Epileptic DrugsKim, R. Y. / Yau, M. C. / Pless, S. A. / Galpin, J. D. / Ahern, C. A. / Kurata, H. T. et al. | 2015
- 21
-
Why are Kinesin-2 KIF3AB and KIF3AC so Processive?Guzik-Lendrum, Stephanie et al. | 2015
- 21
-
Kinesin-5 Acts as a Microtubule Stabilizer, Polymerase and Plus-Tip TrackerChen, Yalei et al. | 2015
- 22
-
Ultrastructure of Dynactin Complex: A Mediator of Cytoplasmic DyneinLander, Gabriel C et al. | 2015
- 22
-
Cytoplasmic Dynein Ring Tilting Detected by Combined polTIRF and Sub-Pixel Particle Tracking of Semiconductor Quantum RodsLippert, Lisa G et al. | 2015
- 22a
-
Mapping Behavior to Neural Anatomy Using Machine Vision and ThermogeneticsBranson, K. / Robie, A. A. et al. | 2015
- 24
-
A Point Mutation Causing Episodic Ataxia Reveals Functional Link between Voltage Sensor and Selectivity Filter in Shaker Kv ChannelsPetitjean, Dimitri et al. | 2015
- 24
-
Site-Specific Cation Release Drives Actin Filament Severing by Vertebrate CofilinDe La Cruz, Enrique M et al. | 2015
- 24
-
Evolutionary Origins of the Shaker Family of Voltage-Gated Potassium ChannelsDiatta, Fortunay H et al. | 2015
- 25
-
How Actin Initiates the Motor Activity of MyosinRopars, Virginie et al. | 2015
- 25a
-
Probing Lipid Vesicle Transport in 3D by Teams of Myosin Va Motors at Suspended Actin Intersections in vitroLombardo, A. T. / Ali, M. Y. / Kennedy, G. G. / Trybus, K. M. / Warshaw, D. M. et al. | 2015
- 26
-
A Minimal System to Establish Microtubule-Based Cell Polarity In VitroRoth, Sophie et al. | 2015
- 26
-
Real-Time Observation of DNA Recognition by the RNA-Guided Endonuclease Cas9 using Single-Molecule FRETDoudna, Jennifer A et al. | 2015
- 26
-
Measurements and Simulations of the Fission Yeast Cytokinetic Ring Tension during ConstrictionChin, Harvey F et al. | 2015
- 27
-
How Flaviviruses use a Unique ‘Slipknot-Like’ Structure to Mechanically Confound a Cellular Exonuclease and Produce Pathogenic RNAChapman, Erich G et al. | 2015
- 27
-
U2 snRNA Conformation is Regulated by Cus2 to Facilitate Dead-Box Protein LoadingTretbar, U. Sandy et al. | 2015
- 28
-
Ligand-Dependent Conformational Cycle of the Na+/Hydantoin Transporter Mhp1Kazmier, Kelli et al. | 2015
- 29
-
Functional Identification of the Na1 Site of the Phosphate Cotransporter NaPi-IIaPatti, Monica et al. | 2015
- 29
-
The Na1 Binding Site in the Human Sodium-Phosphate Cotransporter NaPi-IIaForster, Ian C et al. | 2015
- 30
-
Propogation of the Allosteric Signal in Bacillus Stearothermophilus Phosphofructokinase Examined by Methyl-TROSY NMRWhitaker, Amy M et al. | 2015
- 30
-
Understanding E2 Mechanism using NMRTodd, Emily A et al. | 2015
- 31
-
Microsecond-Resolution Recording of T4 Lysozyme Observes a Brownian RatchetIftikhar, Mariam et al. | 2015
- 31
-
Nothing to Sneeze at: A Full-Scale Computational Model of the Human Influenza VirionReddy, Tyler et al. | 2015
- 31
-
Role Of Membrane-Bending Proteins as Membrane Tension Sensors in Cell MigrationItoh, Toshiki et al. | 2015
- 31
-
Experiment and Simulation Reveal the Bending Properties of Nanoscopic Lipid DomainsNickels, Jonathan D et al. | 2015
- 31
-
Human Neuraminidase Enzymes alter the Lateral Mobility and Function of Integrin ReceptorsCairo, Christopher W et al. | 2015
- 32
-
Long acyl Chain Sphingolipids Govern Visible Microdomains and Cholesterol in Both Model and Plasma MembranesCourtney, Kevin C et al. | 2015
- 32
-
Using Lipopolysaccharides to Create 3-D Multicomponent Biomimetic Membranes on Solid SupportsSwingle, Kirstie L et al. | 2015
- 32a
-
GPI-Anchored Proteins do not Reside in Ordered Domains in the Live Cell Plasma MembraneSevcsik, E. / Brameshuber, M. / Fölser, M. / Weghuber, J. / Honigmann, A. / Schütz, G. J. et al. | 2015
- 33
-
Understanding Enzyme Molecular Evolution toward Thermal Adaptation using Multistate Computational Protein DesignWilson, Corey J et al. | 2015
- 33
-
The Emergence of Heart Failure as a Consequence of Myocardial Metabolic DysfunctionBeard, Daniel A et al. | 2015
- 33
-
Temporal Frequency of Directional Sensing and Collective Migration in DictyosteliumSawai, Satoshi et al. | 2015
- 33a
-
Allosteric Networks in ThrombinKomives, E. et al. | 2015
- 34
-
The Evolution of Enzyme Mechanisms and Functional DiversityThornton, Janet et al. | 2015
- 34
-
Myosin MyopathiesLeinwand, Leslie et al. | 2015
- 34
-
MYBPC3 Gene Therapy for Neonatal Sarcomeric CardiomyopathiesCarrier, Lucie et al. | 2015
- 34
-
Posttranslational Modification of Titin Domains as a Main Regulator of Myocardial StiffnessLinke, Wolfgang A et al. | 2015
- 34a
-
An Integrative Approach to Thin Filament Cardiomyopathies: From Molecular and Computational Biophysics to MiceTardiff, J. et al. | 2015
- 35
-
Resolving Nanoscale Curvature on Lipid Bilayers with Polarized Localization MicroscopyMaarouf, Abir et al. | 2015
- 36
-
Surface Characterization and Membrane Interaction of Double-Knot Toxin, an Activator of TRPV1 ChannelsBae, Chanhyung et al. | 2015
- 36
-
Super Resolution Imaging and Tracking of Protein-Protein Interactions in Sub Diffraction Cellular SpaceLiu, Zhen et al. | 2015
- 36
-
Disease Phenotyping with Sub-Resolution Precision by Single Molecule Tracking in Live AnimalsZhan, Hong et al. | 2015
- 36
-
Super Resolution Fluorescence Microscopy by Cathodoluminescence-Activated ExcitationBischak, Connor G et al. | 2015
- 36
-
3D Superresolution Microscopy by Supercritical Angle DetectionDeschamps, Joran et al. | 2015
- 37
-
The L596-W733 Bond between S4-S5 Linker and TRP Domain Maintains Basal Activity and Enables Inactivation of TRPV4Teng, Jinfeng et al. | 2015
- 37
-
High Temperature Sensitivity is Intrinsic to Voltage-Gated Potassium ChannelsYang, Fan et al. | 2015
- 37a
-
Temperature and Voltage Coupling to TRPM8 Channel OpeningRaddatz, N. / Castillo, J. P. / Gonzalez, C. / Alvarez, O. / Latorre, R. et al. | 2015
- 38
-
TRPM8 is an Ionotropic Testosterone ReceptorAsuthkar, Swapna et al. | 2015
- 38a
-
HIV gp41-Antibody Interaction at the Viral Membrane Interface Defined by EPR SpectroscopySong, L. / Sun, Z. Y. / Kim, M. / Kaur, P. / Wagner, G. / Reinherz, E. L. et al. | 2015
- 40
-
Dimerization of the PTEN Tumor Suppressor and its Structural Characterization by SAXSRoss, Alonzo H et al. | 2015
- 40a
-
Molecular Simulations of the Capsid Release and Membrane Binding Processes of Flock House Lytic PeptidesBrice, A. R. / Nangia, S. / May, E. R. et al. | 2015
- 41
-
Hydrogen Exchange Reveals Differences between Bacterial Chemoreceptor Signaling StatesKoshy, Seena S et al. | 2015
- 41
-
Quantifying Protein-Protein Binding Energy and Entropy using Molecular Dynamics SimulationsRoux, Benoit et al. | 2015
- 41
-
Reconstitution of Multivalent PDZ Domain Binding to the Scaffold Protein PSD-95 Reveals Ternary-Complex Specificity of Combinatorial InhibitionBowen, Mark et al. | 2015
- 42
-
Structure and Dynamics of the Receptor:Kinase Complex that Mediates Bacterial ChemotaxisCrane, Brian R et al. | 2015
- 42
-
Disulfide Trapping and Spectroscopic Studies of Bacterial Chemosensory Core Signaling Complexes: Probing Molecular Mechanisms of Complex Assembly and Receptor-Regulated On-Off SwitchingPiasta, Kene N et al. | 2015
- 42a
-
Architecture and Assembly of Chemoreceptor Arrays as seen by Electron CryotomographyBriegel, A. et al. | 2015
- 43
-
Structure-Based Mechanism for Retroviral Primer AnnealingD'Souza, Victoria et al. | 2015
- 43
-
Tuning Micelle Dimensions and Properties for Stabilizing Membrane Protein Fold and FunctionColumbus, Linda et al. | 2015
- 43a
-
On the Bacterial Cell Wall by Liquid State, Standard and DNP Solid State NMRSimorre, J. P. et al. | 2015
- 44
-
Engineering Synthetic Ribosomes In VitroJewett, Michael et al. | 2015
- 44
-
Evolution Experiment With Translation-Coupled RNA Replication SystemYomo, Tetsuya et al. | 2015
- 45
-
Backbone Dynamics Modulates the Amyloidogenic Propensity of Transthyretin through Non-Native IntermediatesMall, Shyam S et al. | 2015
- 45
-
Computational Modeling of Beta-FibrilsLill, Markus M et al. | 2015
- 45
-
SAS Profile Correlations Reveal the Hierarchical Nature of SAS Data and Suggest New Scoring StrategiesNilges, Michael et al. | 2015
- 46
-
Effect of Hydrophobic Residues on Interfacial Fibrillization KineticsMcBride, Samantha et al. | 2015
- 46
-
The Resveratrol Derivative Piceatannol Alters the Conformation of Alzheimer's Disease Associated Aβ Protein AggregatesWang, Yiying et al. | 2015
- 46a
-
“Push and Pull” Hypothesis to Unify the Physical and Chemical Unfolding of Proteinsde Oliveira, G. A. / Silva, J. L. et al. | 2015
- 47
-
Molecular Basis of Tetramerization and pH-Gating in the KcsA Potassium Channel Cytoplasmic DomainKamnesky, Guy et al. | 2015
- 47
-
Determinants of Domain Swapping in Staphylococcal NucleaseRobinson, Aaron et al. | 2015
- 48
-
Site-Resolved Measurements of Protein Hydration DynamicsMarques, Bryan S et al. | 2015
- 48
-
Internal Cavities and their Role as Determinants of Pressure Unfolding of ProteinsCaro, Jose A et al. | 2015
- 49
-
Crystal Structures of Streptococcus Pyogenes Cas2 Protein at Various pH ConditionsJeong, Ugeene et al. | 2015
- 49a
-
Environmental and Mutation Effects on the Folding and DNA-Binding of the Primary DNA Recognition Subdomain of Sleeping Beauty TransposaseLeighton, G. / Konnova, T. / Nesmelova, I. et al. | 2015
- 50
-
Development of the Line Confocal System for the Single Molecule Tracking of Fast Folding Dynamics of ProteinsOikawa, Hiroyuki et al. | 2015
- 50
-
Folding Rates from Thermodynamics Simulations: Apoazurin as an ExampleCheung, Margaret S et al. | 2015
- 51a
-
Crowding and the Origin of Enthalpic Depletion Forces in Protein InteractionsHarries, D. / Sapir, L. et al. | 2015
- 52
-
Thermally Induced Structural Changes in an Armadillo Repeat Protein Suggest a Novel Thermosensor Mechanism in a Molecular ChaperoneOberhauser, Andres et al. | 2015
- 53
-
Determination of Biomolecular Interactions using Microscale ThermophoresisBouley Ford, Nicole et al. | 2015
- 54
-
Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual ScreeningColas, Claire et al. | 2015
- 54a
-
Understanding the Function of a Pro-Angiogenic Polypeptide hFGF-1 with a Cancer Inhibitor ImatinibModi, T. / Filani, O. / Payne, J. / Murthy, R. et al. | 2015
- 55
-
A Shared Binding Site for Propofol and Thiopental in ELICKinde, Monica N et al. | 2015
- 55
-
Kinase Structural Dynamics Enables Tight and Selective Binding of InhibitorsAgafonov, Roman V et al. | 2015
- 55
-
Crystal View of Anesthetics and Alcohols Bound in the Pore of ELICCohen, Aina E et al. | 2015
- 55a
-
Glutathione Reductase of Plasmodium Falciparum as an Antimalarial Drug Target of Methylene BlueLim, S. / Prieto, J. H. et al. | 2015
- 56
-
Quantifying the Influence of the Crowded Cytoplasm on Small Biomolecule Diffusion via Homogenization TheoryKekenes-Huskey, Peter M et al. | 2015
- 56
-
Using Sedimentation Velocity to Investigate the Nucleotide-Linked Assembly of E. coli ClpALucius, Aaron L et al. | 2015
- 56a
-
Macromolecular Crowder and Ligand Compete for the Closed Domain Cleft of Maltose Binding ProteinGhosh, A. / Zhou, H. X. et al. | 2015
- 57
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Understanding the Molecular Determinants of Capsaicin Mode of ActionElokely, Khaled M et al. | 2015
- 57
-
Formation and Degradation of Intermediate Hemoglobin Polymers are Responsible for the Cooperativity of Oxygen Binding IsothermsBucci, Enrico et al. | 2015
- 57a
-
Role of Ionic Strength and the Bohr Effect in Modulating Thermodynamic Profiles Associated with Co Escape in Rice Non-Symbiotic Hemoglobin 1Butcher, D. / Miksovska, J. et al. | 2015
- 58
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Mapping the Conformational Dynamics of the Scaffold Protein PSD-95Seidel, Claus A.M et al. | 2015
- 59
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Characterizing Nucleotide Dependent Allostery in G-Proteins with Molecular Dynamics and Normal Mode AnalysisYao, Xin-Qiu et al. | 2015
- 59
-
Probing the Domain Motions of an Oligomeric Protein from Deep-Sea Hyperthermophile by Neutron Spin EchoRusek, Andrew J et al. | 2015
- 60
-
Thermodynamic and Dynamic Basis for the Broadened Ligand Specificity of a Tiam2 PDZ Domain MutantGolden, Lisa C et al. | 2015
- 60
-
Probing Multiple Timescale Dynamics of Protein Kinase A-Inhibitor ComplexesMcDonald, Leanna et al. | 2015
- 62
-
Tau Filament Length Distribution Reflects End-To-End AnnealingHuseby, Carol J et al. | 2015
- 62a
-
How Unfolded is Tau?Foroutan, A. / Robinson, A. S. et al. | 2015
- 63
-
Exploring the Phase Space of Alpha-Synuclein with Replica Exchange SimulationsBolhuis, Peter G et al. | 2015
- 63
-
Disease Related Point Mutations and Solution Conditions Determine Fibrillization Behavior of α-SynucleinSidhu, Arshdeep et al. | 2015
- 64
-
Studying α-Synuclein Misfolding through Förster Resonance Energy TransferHaney, Conor M et al. | 2015
- 64
-
Site-Specific Dynamics of Aβ1-23 Amyloid Formation and Fibrillar Configuration using an Unnatural Amino AcidDu, Deguo et al. | 2015
- 64
-
Investigating the Trimethylamine N-Oxide (TMAO) Induced Structure of α-SynucleinFerrie, John J et al. | 2015
- 64a
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Binding of Aβ Monomer to DMPC Bilayer using Isobaric-Isothermal Replica Exchange Molecular DynamicsLockhart, C. / Klimov, D. K. et al. | 2015
- 65
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Reconfiguration of the Alzheimer's Peptide Kinetically Controls Aggregation in Alzheimer's DiseaseAcharya, Srabasti et al. | 2015
- 65
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Microtubule Networks Modulate Cellular Susceptibility to Aβ-Mediated ToxicityShamitko-Klingensmith, Nicole et al. | 2015
- 65
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Amyloid-β Oligomers: Now for the Structure in the MembraneBhowmik, Debanjan et al. | 2015
- 66
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Alzheimer's Protective A2T Mutation Changes the Conformational Landscape of the Aβ1-42 Monomer Differently than does the A2V MutationDas, Payel et al. | 2015
- 66
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Effects of Carbon Nanoparticles on the Aggregation of Alzheimers Beta-Amyloid PeptideWei, Guanghong et al. | 2015
- 67
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Mechanistic Insights of Hexameric Helicase Function Provided by Single-Molecule FRETCarney, Sean M et al. | 2015
- 67
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Studies of the FtsK DNA Translocase using Two-Color Tethered Fluorophore MotionMay, Peter F.J et al. | 2015
- 67a
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Effects of DNA Structural and Topological Constraints on HMGA2 BindingZhao, X. / Dröge, P. / Yan, J. et al. | 2015
- 68
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Investigation of the Tus-ter Blocking Efficacy during the Chromosome Replication of Live Escherichia Coli CellsKrishnan, Sriram Tiruvadi et al. | 2015
- 68
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Single-Molecule Analysis of Transcription-Coupled RepairFan, Jun et al. | 2015
- 68
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Direct Visualization of DNA Replication Conflicts in the Bacterial CellMangiameli, Sarah et al. | 2015
- 68
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RecG Interaction with the DNA Replication Fork. The Role of E. coli SSB ProteinSun, Zhiqiang et al. | 2015
- 69
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Real-Time RecA Filament Disassembly in the Presence of RecX Monitored using Single-Molecule Manipulation by Optical TweezersPobegalov, Georgii et al. | 2015
- 69
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Influence of DNA Conformation and Repair Enzyme on Guanine and 8-Oxoguanine Base FlippingLa Rosa, Giuseppe et al. | 2015
- 69
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Toward Adding Complexity in Single Molecule FRET Studies of DNA Mismatch Repairweninger, keith et al. | 2015
- 69
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Interplay MutS with β Clamp on Mismatched DNAOh, Jungsic et al. | 2015
- 70
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Elucidating the Transition Dynamics of HIV-1 Reverse Transcriptase using Single Molecule FRETGanji, Mahipal et al. | 2015
- 70
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Resolving the Kinetic States of a Proofreading DNA PolymeraseWuite, Gijs et al. | 2015
- 70
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Cardioprotective Effect of Exercise Training in Heart Failure Rats: Exercise Training Reduces Oxidative Stress Induced Nuclear Genomic FragmentationSolvang-Garten, Karin et al. | 2015
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Single-Molcule Studies on DNA Transportation Motors with Common Revolution Mechanism without RotationVieweger, Mario et al. | 2015
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The Mechanism of Rolling Circle DNA Replication and the Roles of Initiator Protein RepDSoutherden, Lesley F et al. | 2015
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Nucleotides Linkage Analysis of RecBCD DNA HelicaseGaydar, Vera et al. | 2015
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Revolution Motors in Cell for Transportation of Lengthy Chromosome without Coiling or TorqueZhao, Zhengyi et al. | 2015
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Cooperative Activity of SARS Coronavirus Nsp13 Helicase Characterized by Single Molecule FRETIm, Hyeryeon et al. | 2015
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Dynamic Control of Processivity during DNA Degradation by a Ring-Shaped NucleasePark, Suyeon et al. | 2015
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The Role of DNA Shape in Nucleosome Formation and PositioningLequieu, Joshua P et al. | 2015
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Studies of the Compaction Mechanisms of DNA-Binding Proteins using Horizontal Magnetic TweezersFabian, Roberto et al. | 2015
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Elucidation of DNA Packaging and Mispackaging in Sperm Nuclei by X-Ray ScatteringHutchison, James M et al. | 2015
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The Effect of HU Protein on Lac-Repressor-Mediated DNA LoopingDunlap, David D et al. | 2015
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Effect of an Oxidative Guanine Lesion on Nucleosome StabilityGoehring, Liana et al. | 2015
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Yeast HMGB Proteins Both Disrupt and Compact NucleosomesHuo, Ran et al. | 2015
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Effects of Cationic Residues and Base Sequence in Nucleic Acid Binding of Histone-Derived Antimicrobial PeptidesSim, Sukin et al. | 2015
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Unraveling the Structural, Dynamic, Thermodynamic, and Kinetic Heterogeneity in DNA Site Recognition by Structurally Homologous ETS Transcription FactorsPoon, Gregory M.K et al. | 2015
- 75
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Using Contrast Variation with SAXS to Visualize DNA Dissociation from Nucleosome Core ParticlesTokuda, Joshua M et al. | 2015
- 75
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Global Characterization of Transcription Factor Localization and Partitioning in Escherichia ColiKuwada, Nathan J et al. | 2015
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Glucocorticoid Receptor-DNA Dissociation Kinetics Measured in vitro Reveal Exchange on the Second TimescaleDe Angelis, Rolando W et al. | 2015
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Histone Phosphorylation Combined with Acetylation Dramatically Increase Nucleosome AccessibilityBrehove, Matthew S et al. | 2015
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Hydration-Modulated Collective Dynamics of Membrane Lipids are Revealed by Solid-State 2H NMR RelaxationMolugu, Trivikram R et al. | 2015
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Spot Variation FCS in the 2D Ising ModelVeatch, Sarah et al. | 2015
- 77
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Faster Calculations of Diffusion Constants for Lipids, Water and ProteinsLerner, Michael et al. | 2015
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Structural and Dynamical Properties of POPC Bilayers Supported on Nanoporous SubstratesDuro, N. D. / Gjika, M. / Scott, L. / Varma, S. et al. | 2015
- 78
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How Reliable are Molecular Dynamics Simulations of Membrane Active Antimicrobial PeptidesWang, Yukun et al. | 2015
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Transient Effect of Calcium Influx on PIP2 Clusters and Cholesterol-Stabilized Nano-Domains in the Inner Plasma Membrane Leaflet of Intact CellsPralle, Arnd et al. | 2015
- 79
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Membrane Cytoskeletal Changes during In-Situ to Invasive Progression of Breast Cancer Cells Observed by Multi-Scale Diffusion Analysis of Transmembrane ProteinsSimsek, Muhammed F et al. | 2015
- 80
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Phase Transition and Formation of Transmembrane Pore in Stretched Phospholipid Bilayer Including Cholesterol: Molecular Dynamics SimulationShigematsu, Taiki et al. | 2015
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Characterizing the Shiga Toxin-Receptor InteractionVenkat, Swati et al. | 2015
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Morphological Modifications of the Early Secretory Pathway in Differentiating Skeletal Muscle CellsGiacomello, Emiliana et al. | 2015
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Imaging the Assembly of Perfringolysin OSenior, Michael J et al. | 2015
- 81
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Aerolysin Block by Single Polyethylenegycol Oligomers: Mass Sensitivity and Voltage DependenceBacri, Laurent et al. | 2015
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Polyamidoamine Dendrimers as Universal Pore-Blocking Binary Toxin InhibitorsKalu, Nnanya U et al. | 2015
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Key Residues in Vibrio Cholerae Cytolysin Involved in Membrane BindingDe, S. / Bubnys, A. / Hyun, J. / Olson, R. et al. | 2015
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Arginine-Glycosaminoglycan Interaction Regulates Penetration Efficiency of Arginine-Rich Cell-Penetrating Peptides in Biological MembraneTakechi, Yuki et al. | 2015
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Bilayer Perturbation is a Predictive Parameter for Antimalarial DevelopmentRamsey, Nicole et al. | 2015
- 83
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Specific Delivery of Auristatins to Tumor Cells using pHLIPBurns, Kelly et al. | 2015
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Understanding the Function of the Cyclic Antifungal Lipopeptide Fengycin using All-Atom Md SimulationSur, Sreyoshi et al. | 2015
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Experimental Assessment of Tilt-Dependent Thermal Fluctuations in Lipid BilayersAkabori, Kiyotaka et al. | 2015
- 84a
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Structural Effects of Urea and Tmo on Lipid BilayersFunari, S. S. / Valerio, J. et al. | 2015
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Chelating Agent Induction of Multiphase Coexistence in Lipid MultilayersWeisman, Michael et al. | 2015
- 85
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DPPC Monolayers Exhibit an Additional Phase Transition at High Surface PressureShen, Chen et al. | 2015
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Partitioning of the Transmembrane Peptide GWALP23 between Lo and Ld Phases in Macro and Nanoscale Domains. Nanometer-Scale Domains can be Treated as a PhaseEnoki, Thais A et al. | 2015
- 86
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How do Cholesterol and Saturated Sphingolipids Affect Acyl Chain Order in the Fluid Phase of Binary POPC Bilayers - a Study with 1-oleoyl-2-propionyl-DPH-sn-glycero-3-phosphocholineEngberg, Oskar et al. | 2015
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Hydrocarbon Thickness Dictates Cholesterol's Location, Orientation and Motion in a Phospholipid BilayerHeberle, Frederick A et al. | 2015
- 86a
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Cell Cycle Position Determines Critical Temperatures in Plasma Membrane VesiclesGray, E. M. / Veatch, S. L. et al. | 2015
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Molecular and Mechanical Manipulation of Membrane Domains in Planar Supported BilayersWarner, Rochelle et al. | 2015
- 87
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Revisiting the Link between Lipid Membrane Elasticity and Microscopic Continuum ModelsTerzi, M. Mert et al. | 2015
- 87
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Do Gel Phase Lipid Bilayers Behave Like Euler Elastica?Diggins, Patrick M et al. | 2015
- 87
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Why Cholesterol should be Found Largely in the Cytoplasmic Leaf of the Plasma MembraneSchick, Michael et al. | 2015
- 88
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Physical Properties and Membrane Packing in Hybrid ArchaeosomesChong, Parkson L.G et al. | 2015
- 88
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Temperature-Dependent Lipid Phase Transitions Occurring in Higher OrganismsNossal, Ralph et al. | 2015
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Bolalipid Membranes: Elasticity Theory ApproachGalimzyanov, Timur R et al. | 2015
- 88
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Molecular Level Modeling of the Effects of Charge and Sugars on the Phase Equilibrium of Model Lipid BilayersCeleste Kennard, Shauna et al. | 2015
- 88
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Edge Structure of through Pore in Lipid MembraneAkimov, Sergey A et al. | 2015
- 89
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Thermotropic Behavior of Cardiolipin and Dimyristoylphosphatidylcholine Bilayers in the Presence and Absence of CalciumSchwall, Christine et al. | 2015
- 89
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pH-Dependent Conformational Changes in the Influenza a M2 Full-Length Protein in Lipid BilayersEkanayake, E. Vindana et al. | 2015
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The Beginning of the End: Cardiolipin, Cytochrome C and the Apoptotic TriggerO’Brien, E. S. / Nucci, N. V. / Fuglestad, B. / Valentine, K. G. / Wand, A. J. et al. | 2015
- 91
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Membrane Protein Misfolding Enforces the Positive-Inside RuleLast, Nicholas B et al. | 2015
- 91
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Neisserial Opa Protein Dynamics and Interaction with Host Ceacam ReceptorsKieber, Marissa K et al. | 2015
- 91
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Coexistence of Native-Like and Non-Native Misfolded Ferricytochrome C on the Surfac of Cardiolipin Containing LiposomesPandiscia, Leah A et al. | 2015
- 91
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Prion Proteins and Mechanisms of Interaction with Model MembranesSoto, Patricia et al. | 2015
- 92
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Interaction of the Phage Endolysin PlyC with Model MembranesBarros, Marilia et al. | 2015
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Identifying the Oligomerization State of DegP in the Absence and Presence of SubstrateCostello, Shawn M et al. | 2015
- 92
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Developing a Universal Steric Trapping Strategy for Studying Folding and Stability of Helical Membrane ProteinsGaffney, Kristen A et al. | 2015
- 93
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Mechanism of Action of Salt Adaptation Mutations in Artemia FranciscanaEastman, Jessica et al. | 2015
- 93
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Nucleotide-Dependent Membrane Interaction and Dimerization of K-Ras4BJang, Hyunbum et al. | 2015
- 94
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Oligomer Stoichiometry of Membrane-Bound Proteins Involved in a Cooperative Partition Equilibrium: A Homo-FRET StudyMelo, Ana M et al. | 2015
- 95
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Localization and Dynamics of Beta-Adrenergic Receptor Mediated EGFR Transactivation on Micro-Patterned SurfacesKrasel, Cornelius et al. | 2015
- 95
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Allosteric Effects of G-Protein Coupled Receptor Heteromerization: Relevance to PsychosisBaki, Lia et al. | 2015
- 95
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Microtubules Shape GPCR Spatiotemporal Membrane Organization and Function by Scaffolding Cortical Signaling Hubsde Keijzer, Sandra et al. | 2015
- 95a
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Membrane Curvature Regulates the Localization of G Protein Coupled Receptors and Ras IsoformsStamou, D. / Rosholm, K. / Damalas, A. / Hatzakis, N. / Wirth, V. / Martinez, K. / Leijnse, N. / Oddershede, L. / Bendix, P. M. / Pedersen, S. et al. | 2015
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Novel Chemical Biology Methods Illuminate the Function of Single G Protein-Coupled ReceptorsHuber, Thomas et al. | 2015
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Polymer-Based Nanodiscs for Studying Structure and Dynamics of G-Protein-Coupled ReceptorsBroecker, Jana et al. | 2015
- 97
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Tracking Voltage-Sensitive Movements of the M2 Muscarinic Acetylcholine ReceptorBarchad-Avitzur, Ofra et al. | 2015
- 97
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Lck Cluster Dynamics in Live CellsBaumgart, Florian et al. | 2015
- 97a
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The B Cell Receptor Dictates its Local Lipid EnvironmentStone, M. B. / Veatch, S. L. et al. | 2015
- 98
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The T Cell Receptor Resides in Ordered Plasma Membrane Nanodomains that Aggregate Upon T Cell ActivationParmryd, Ingela et al. | 2015
- 98
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Reinforcement of Integrin-Mediated T-Lymphocyte Adhesion by TNFLi, Qian et al. | 2015
- 98
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Establishing the Structural Rules for Ligand Recognition, Signaling and Assembly in Innate Immune ReceptorsFebbraio, Mark A et al. | 2015
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Plasma Membrane Organization Promotes CD36 Signal Transduction in Endothelial CellsMaringa, J. G. / Vega, A. / Davidson, M. W. / Jaqaman, K. / Touret, N. et al. | 2015
- 99
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Closure of Pre-Existing Ω Profiles Mediates Compensatory Endocytosis, Endocytosis Overshoot and Bulk EndocytosisShin, Wonchul et al. | 2015
- 99
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A DNA Origami Platform for Protein Interaction AnalysisMotsch, Viktoria et al. | 2015
- 99
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Sending Innate Immune Signals Across the Membrane: A Multiscale Simulation Approach to Toll-Like Receptor AssemblyKargas, Vasileios E et al. | 2015
- 100
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How Half-Coated Janus Particles Enter CellsGao, Yuan et al. | 2015
- 100
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Cell Spreading Size Regulates Size of Clathrin-Coated Pits through TensionLiu, Allen et al. | 2015
- 100
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Antibody Induced PLAP Endocytosis is Dependent on the Structure and Amount of Sterols in Cellular Plasma MembraneKim, Ji Hyun et al. | 2015
- 100a
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Controlling Stimulus-Secretion Coupling in Adrenal Chromaffin Cells: A Novel Role for the Serotonin Transporter?Brindley, R. L. / Blakely, R. D. / Currie, K. P. et al. | 2015
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Fusion of Lysosomes with Secretory Vesicle Leads to Excessive Uncontrolled Exocytosis in Mucolipidosis Type IVAhuja, Malini et al. | 2015
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Fusion Properties of Gliotransmitter Vesicles in Cultured AstrocytesGuček, Alenka et al. | 2015
- 102a
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Induction of Hippocampal Synapses on Functionalized MicropatternsTrahe, J. / Keller, U. / Tsytsyura, Y. / Huve, J. / Reissner, C. / Missler, M. / Piehler, J. / Klingauf, J. et al. | 2015
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Synaptotagmin-1 and Synaptotagmin-7 Differ in their Stimulus and Ca2+-Dependence of ActivationRao, Tejeshwar C et al. | 2015
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Granuphilin C2A Domain as a Coincidence Detector for Phosphatidylserine and PhosphoinositidesWatson-Siriboe, A. / Lyakhova, T. A. / Knight, J. D. et al. | 2015
- 104
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The Membrane Bending Action of the Syt-1 C2AB Studied on Supported Lipid BilayersMacConnachie, Lauren P et al. | 2015
- 104
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Mechanics Regulates ATP-Stimulated Calcium Response in Fibroblast CellsLembong, Josephine et al. | 2015
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Calcium Movement in Cardiac MitochondriaBoyman, L. / Williams, G. S. / Chikando, A. C. / Khairallah, R. J. / Kettlewell, S. / Ward, C. W. / Smith, G. L. / Kao, J. P. / Lederer, W. J. et al. | 2015
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Modulating Calcium Entry into Microvascular Endothelium by Controlling Membrane Potential During Submaximal Muscarinic Receptor ActivationBehringer, Erik J et al. | 2015
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Reduced IP3-Mediated Ca2+ Signaling in Autism Spectrum Disorders in the Context of Fragile X and Tuberous Sclerosis SyndromesSchmunk, Galina et al. | 2015
- 105
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Calcium Dynamics and Homeostasis in Breast Cancer OncogenesisLlongueras, José P et al. | 2015
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Buffering Effects on the LCC Current and Spatiotemporal Ca2+ DynamicsGarber, L. / Greiser, M. / Williams, G. S. / Lederer, W. J. et al. | 2015
- 106
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Physical Coupling between SERCA2 and PDE3A Regulates SERCA2 Activity in CardiomyocytesSkogestad, Jonas et al. | 2015
- 106
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Purified IgGs from Type 2 Diabetes with Atrial Fibrillation Induce Intracellular Calcium Release in Cardiomyocytes through IP3 PathwayLuo, Yanhong et al. | 2015
- 106
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Ventricular Wall Stress Predicts Disruption of Cardiomyocyte T-Tubule Structure and Ca2+ Homeostasis across the Infarcted HeartFrisk, Michael et al. | 2015
- 106a
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A Novel Role for B-Type Natriuretic Peptide and Phosphodiesterase 2A in Cardiac Sympathetic Neurons from Prehypertensive RatsLi, D. / Hao, G. / Liu, K. / Woodward, L. / Ioannides, D. / Lu, C. J. / Paterson, D. J. et al. | 2015
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MG56, a Member of the MBOAT Family of Proteins, Regulates Intracellular Calcium Signaling in Striated MuscleLin, Pei-Hui et al. | 2015
- 108
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Cisplatin-Induced Cachexia in rats Causes Alterations in Skeletal Muscle Calcium HomeostasisConte, Elena et al. | 2015
- 108
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STIM1 Enhances SR Ca2+ Content through Inhibiting Phospholamban in Rat Ventricular MyocytesZhao, Guiling et al. | 2015
- 108
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Role of Mitochondrial Ca2+ Uniporter in Radiation-Induced Cell DamageLiu, Xibao et al. | 2015
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In vivo Temperature Sensitivity of the Calcium Affinity of fluo-5F and mag-fluo4Kao, Joseph P.Y et al. | 2015
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A Novel Red Fluorescence Calcium Indicator for Functional Analysis of GPCRs and Calcium Channel TargetsZhao, Q. / Guo, H. / Yi, G. / Liao, J. / Diwu, Z. et al. | 2015
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Translocation between PI(4,5)P2-Poor and PI(4,5)P2-Rich Microdomains During Store Depletion Determines STIM1 Conformation and Gating of Orai1Muallem, Shmuel et al. | 2015
- 110
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Coupling Interactions of the Dimeric SOAR Unit of STIM1 with Orai1 ChannelsZhou, Yandong et al. | 2015
- 110
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Differential Effects of Antiarrhythmic Drugs Vernakalant and Flecainide on Human Two-Pore-Domain K+ ChannelsThomas, Dierk et al. | 2015
- 110
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Sparfloxacin, a Fluoroquinolone Antibiotic, Slows Inactivation of L-Type Ca2+ Current in Neonatal Rat Ventricular MyocytesKim, Jae Gon et al. | 2015
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Classifying the Electrophysiological Effects of Chronotropic Drugs on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes using Voltage Sensitive Dyes and Supervised Machine LearningHeylman, Christopher M et al. | 2015
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Electrophysiology of Cardiac Tissue Slices before, during, and after StretchWang, K. / Mu-u-min, R. / Terrar, D. / Gavaghan, D. G. / Kohl, P. / Bollensdorff, C. et al. | 2015
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Electronic Expression of IK1 in Human Induced Pluripotent Stem Cell Derived Cardiocytes Reveals Atrial vs Ventricular Specific PropertiesKaplan, Aaron D et al. | 2015
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Activation of Ca2+-Dependent Cation Current by Fluid Shear Force in Atrial MyocytesSon, Min-Jeong et al. | 2015
- 112
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Normalization of Action Potential Properties in Human Induced Pluripotent Stem Cell Derived Cardiocytes by Electronic Expression of IK1Kaplan, Aaron D et al. | 2015
- 112a
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STIM1 Increases Ca2+ Stores in the Sarcoplasmic Reticulum of Adult Feline Ventricular MyocytesTroupes, C. / Houser, S. et al. | 2015
- 113
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Regional Heterogeniety of the Inwardly Rectifying Potassium Current in the Canine HeartPanama, Brian et al. | 2015
- 113
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Action Potential Repolarization in Equine HeartsCalloe, Kirstine et al. | 2015
- 114
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Macromolecular Crowding in the Cytosol: Underappreciated or Overestimated?Groen, Joost et al. | 2015
- 114
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A Sensor for Quantification of Macromolecular Crowding in Living CellsBoersma, Arnold J et al. | 2015
- 114
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Rapidly Inducible De Novo Synthesis of Hydrogels in Living CellsInoue, Takanari et al. | 2015
- 114a
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Thermodynamics and Kinetics of Multi-Protein Binding in Crowded EnvironmentsKim, Y. / Mittal, J. et al. | 2015
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Structure-Function Relations and Rigidity Percolation in Biopolymer Networks in Live Tissue under Shear: Bovine Articular Cartilage as a Model SystemSilverberg, Jesse L et al. | 2015
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Nuclear Damage in Highly Constrained Migration: From Lamina Defects to DNA BreaksIrianto, J. / Athirasala, A. / Diegmiller, R. / Ivanovska, I. / Discher, D. E. et al. | 2015
- 116
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A Computational Model for E. coli Cytoplasm: Diffusion and HydrodynamicsHasnain, Sabeeha et al. | 2015
- 116
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Diffusion Coefficient as a Function of Mass for Globular BiomoleculesSaxton, Michael J et al. | 2015
- 117
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Testing the Hydration Status of the Shaker-K Channel Voltage Sensor Domain with SugarsDíaz-Franulic, Ignacio et al. | 2015
- 117
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State Dependent Photo-Crosslinking of the IKS Channel Complex Demonstrates Movement of KCNE1 at Pre-Opening Membrane PotentialsMurray, Christopher I et al. | 2015
- 118
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Non-Canonical Start Codons Reinitiate Translation in N-Terminal Truncated Kv ChannelsKalstrup, Tanja et al. | 2015
- 118
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Ion Permeation in Potassium Channels Involves Direct Coulomb Knock-On between IonsZachariae, Ulrich et al. | 2015
- 118
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The Effect of D2O on the Inactivation Kinetics and Recovery from Slow Inactivation of Shaker-IR K+ ChannelsPanyi, Gyorgy et al. | 2015
- 118
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Dynamics of the KcsA Selectivity Filter Probed using Intrinsic Tyrosine FluorescenceRaghuraman, H et al. | 2015
- 119
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Voltage Dependence of BK Channels Gating Ring Motion Studied by State Dependent FRETMiranda, Pablo et al. | 2015
- 119
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Quantitative Mapping of Interactions in the Voltage-Sensor Pore Interface of the Shaker Potassium ChannelOelstrom, Kevin et al. | 2015
- 120
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The Conformation of KcsA's Selectivity Filter Influences the Opening of its Activation GateCortes, D. Marien et al. | 2015
- 120
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Reconstitution and Measurement of Ion Channel Ensembles in Droplet BilayersVijayvergiya, Viksita et al. | 2015
- 120
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Engineering hERG Channel Inner Cavity within KcsA StructureCortes, D. Marien et al. | 2015
- 120
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K+-Dependent Selectivity and External Calcium Block of Shab Potassium ChannelsGomez-Lagunas, Froylan et al. | 2015
- 120
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Block of HERG by Extracellular Calcium and other Divalent IonsNguyen, Andrew et al. | 2015
- 121
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Stoichiometry of a hERG1 Agonist on Channel GatingWu, Wei et al. | 2015
- 121a
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The Role of Met-691 in Heme-Dependent Regulation Supports the Presence of a Cytochrome-C-Like Structure in Human BK ChannelsYusifov, T. / Savalli, N. / Park, S. / Pantazis, A. / Olcese, R. et al. | 2015
- 122
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Cadmium Coordination by Cysteines Introduced in the BK Inner Pore and its Structural and Functional ImplicationsZhou, Yu et al. | 2015
- 122
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Mutations in the S4/S5 Linker and S6 of Slo1 Ablate the Response to the Novel BK Channel Opener GoSlo-SR-5-6Kshatri, Arvind et al. | 2015
- 123a
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Probing Temperature Sensing of Thermal TRP Channels by CalorimetryAndra, K. / Saxena, A. / Liu, B. / Qin, F. et al. | 2015
- 124
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Proton as a Dual Regulator for TRPV1Lee, Bo Hyun et al. | 2015
- 124
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Dietary Capsaicin and Exercise: Analysis of a Two-Pronged Approach to Counteract ObesityFettel, Kevin et al. | 2015
- 124a
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Insight into the Structure of Tetramer hTRPV1 from Homology Modeling, Molecular Docking, Molecular Dynamics Simulation and Virtual ScreeningFeng, Z. et al. | 2015
- 125
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A Single-Residue Switch for High Temperature Dependence of Thermal TRPV3 ChannelsLiu, Beiying et al. | 2015
- 126
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Use-Dependent Activation of Neuronal Kv1.2 Channel ComplexesBaronas, Victoria A et al. | 2015
- 126
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The Spider Toxin GsMTx-4 Blocks TRPV4 Cation Channels Expressed in HEK-293 CellsBrinkmeier, Heinrich et al. | 2015
- 126a
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The Role of ROS in Tethering CFTR within Ceramide Platforms at the Plasma MembraneAbuArish, A. / Wiseman, P. W. / Hanrahan, J. W. et al. | 2015
- 127
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A New Class of Positive Gating Modulators of hKv3.2 Channels: Insights into the Mechanism of ActionLiang, Qiansheng et al. | 2015
- 127
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Solution NMR to Investigate Gating in the NaK ChannelBrettmann, Joshua et al. | 2015
- 127
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Cardiac Sodium Channel: Activation by CaM Involves a NaV1.5-NaV1.5 InteractionBoto, Agedi et al. | 2015
- 127
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Refinement and Evaluation of a CFTR Homology Model and Identification of Residues Controlling Channel GatingStock, Gorman et al. | 2015
- 128
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Defining Post as a Modulator of STIM1 Function during T Cell ActivationGo, Christina et al. | 2015
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Pegylated Cholesterol and Methyl-Beta-Cyclodextrin are Modulators of L-Type Calcium Channel Current and Decrease Membrane Capacitance in Vascular Smooth Muscle CellsGupte, Sachin A et al. | 2015
- 128a
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The Sigma1 Receptor Competes with STIM1 to Bind Orai1 to Regulate Store Operated Calcium Entry (SOCE)Srivats, S. / Balasuriya, D. / Pasche, M. / Vistal, R. / Taylor, C. W. / Edwardson, M. J. / Murrell-Lagnado, R. D. et al. | 2015
- 129
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Direct Contacts of K+ Ions in the Selectivity Filter Enable the High Conductance of K+ ChannelsSong, Chen et al. | 2015
- 129
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STIM1 Binding to Both the N' and C' Termini of Orai1 is Critical for Gating of CRAC ChannelsPalty, Raz et al. | 2015
- 129a
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Evolutionary Diversity of Protein Nanodomains within Mammalian SpermMiller, M. R. / Kenny, S. J. / Mansell, S. A. / Xu, K. / Lishko, P. et al. | 2015
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Characterizing Protein Binding of Phospholamban to SERCA using Chemical Cross-LinkingSivakumaran, Vidhya et al. | 2015
- 130
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Bridging Integrator 1 (BIN1) Initiates T-Tubule Growth during Cardiac Development and DiseaseLipsett, David B et al. | 2015
- 131
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Atomic-Level Characterization of the Inhibition Mechanism of the Calcium Pump by PhospholambanRamírez-Salinas, G. Lizbeth et al. | 2015
- 131
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Using Molecular Dynamics Simulations to Interpret Fluorescence and EPR Data on Labeled SERCA and PhospholambanSvensson, Bengt et al. | 2015
- 131
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Phospholamban Phosphorylation Alters its Conformational Equilibrium to Regulate SERCA ActivityVeglia, Gianluigi et al. | 2015
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Novel Roles of Gq-Dependent Signal Transduction for Cardiac Pacemaking and Cardiac Impulse Propagation Studied by Gq-KO and a DREADDKaiser, Elisabeth et al. | 2015
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Mitochondrial Abnormalities in a Mouse CPVT Model with RyR2 Loss-Of-Function MutationValdivia, Hector H et al. | 2015
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A Simple Regulation of Cardiomyocyte ExcitabilityMoshal, Karni S et al. | 2015
- 133
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The HCM Mutation L348P in cMyBP-C Enhances Thin Filament Activation through Tropomyosin ShiftKensler, Robert W et al. | 2015
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Crossbridge Arrangement in Cardiac Thick Filaments Isolated from cMyBP-C Phosphomimetic MiceKensler, Robert W et al. | 2015
- 134a
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Motor Coordination in Long-Distance Transport in AxonsChowdary, P. / Che, D. / Cui, B. et al. | 2015
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Mechano-Chemical Model for the Stepping of Cytoplasmic DyneinŠarlah, Andreja et al. | 2015
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Kinesin-2's Role in Intracellular Cargo Transport: Navigating the Complex Microtubule LandscapeHoeprich, G. / Hancock, W. / Berger, C. et al. | 2015
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Kinesin Regulation Dynamics through Cargo Delivery, a Single Molecule InvestigationKovacs, Anthony P.I et al. | 2015
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Cooperative Transport by Populations of Fast and Slow Kinesins Uncovers Novel Family-Dependent Motor Characteristics Important for in vivo FunctionHancock, William O et al. | 2015
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Effect of Force and Discrete Step-Size on the Velocity Distribution of Processive Molecular MotorsVu, Huong T et al. | 2015
- 136a
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Development of Photo-Controlled Molecular Shuttle Utilizing ATP Driven Motor KinesinNumata, N. / Kondo, K. / Maruta, S. et al. | 2015
- 137
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Kinetic Characterization of Rice Plant Specific Kinesin E11 using Fluorescent ATP AnalogueTaniguchi, Hironobu et al. | 2015
- 137
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Study of Phospho-Regulation of a Mitotic Kinesin using a Directed Evolution ApproachGoldstein, Alina et al. | 2015
- 137
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Photo-Control of Mitotic Kinesin Eg5 using Thiol Group Reactive Fulgimide DerivativeTamura, Yuki et al. | 2015
- 137a
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Photo-Regulation of Kinesin Intramolecularly Crosslinked by Bifunctional Azobenzne Derivative at the Coiled-Coil Stalk RegionFujio, H. / Kondo, K. / Maruta, S. et al. | 2015
- 138
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High Speed Microscopy for Observing the Stepping Behavior of Kinesin-1 Motors at Saturating ATPHancock, William O et al. | 2015
- 138
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Processivity of Kinesin-2 Results from Rear-Head Gating and Not Front-Head GatingChen, Geng-Yuan et al. | 2015
- 138
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Impact of Structural and Dynamical Complexity on Kinesin KineticsJacobson, Bruna D et al. | 2015
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Characteristics of Cell Shape in Two DimensionsAlizadeh, E. / Lyons, S. M. / Mannheimer, J. / Castle, J. / Plomondon, R. / Prasad, A. et al. | 2015
- 140
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Co-Culture Changes the Mechanical Properties of CellsGuo, Xinyi et al. | 2015
- 140a
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Quantitation of Compositional Changes in the Non-Erythroid Membrane Skeleton due to External ForcesDegaga, E. K. / Forstner, M. B. et al. | 2015
- 141
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Characterizing Mechanical Forces during B Cell ResponsesSpillane, Katelyn M et al. | 2015
- 141
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Vimentin Intermediate Filament Mechanics in Cells under Shear StressWu, Huayin et al. | 2015
- 141
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The Role of Cellular Mechanical Properties in Microenvironment-Dependent BehaviorPak, Iris et al. | 2015
- 141
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Atomic Force Microscopy of Triple Negative Breast Cancer Cells: A Predictive Value of Mechanical PhenotypeOsmulski, Pawel A et al. | 2015
- 142
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AFM Indentation Reveals Actomyosin-Based Stiffening of Metastatic Cancer Cells during Invasion into Collagen I MatricesDoss, Bryant L et al. | 2015
- 142
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Cytoskeletal Forces during T Cell ActivationUpadhyaya, Arpita et al. | 2015
- 142a
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Pharmacological Activation of Myosin II to Correct Pancreatic Cancer Cell MechanicsSurcel, A. / Zhu, Q. / Schiffhauer, E. / Anders, R. / Robinson, D. et al. | 2015
- 143
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Insights on RGD-Based Peptide Interactions with Integrin Receptors from Atomistic SimulationsRammohan, Aravind et al. | 2015
- 143
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SH3 Domain of C-Src Regulates its Dynamic Behavior in the Cell MembraneYamaguchi, Tomoyuki et al. | 2015
- 143
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Deletion of h2-calponin in Macrophages Facilitates Cell Motility and Lipid Clearance: A Novel Mechanism to Attenuate Arterial AtherosclerosisJin, Jian-Ping et al. | 2015
- 143
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h2-calponin Gene Knockout Increases Traction Force of Mouse Fibroblasts in vitroHossain, M. Moazzem et al. | 2015
- 143a
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Arrayed Lipid Membranes on Femtoliter Chambers Allow Highly Sensitive Detection of Ion Translocation Catalyzed by Transporter ProteinWatanabe, R. / Soga, N. / Noji, H. et al. | 2015
- 144
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Na+/K+ Pump Ion Binding Site Interactions Regulate the Proton Leak PathwayStanley, Kevin et al. | 2015
- 144
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Protonation States of Key Acidic Residues at the Ion Binding Sites in Na/K Pump by QM CalculationsTsunekawa, Naoki et al. | 2015
- 145
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Conformational Changes and Complex Formation of the Non-Canonical Ribose ABC TransporterErramilli, Satchal K et al. | 2015
- 145
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Movement of the Nucleotide Binding Domains in the ABC Transporter MsbA Reconstituted in NanodiscsZoghbi, Maria E et al. | 2015
- 145
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A Combination of Curcumin with Either Gramicidin or Ouabain Selectively Kills Cells that Express the Multidrug Resistance-Linked ABCG2 TransporterLiu, Haiyan et al. | 2015
- 146
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Reconstitution of Multidrug Resistance Efflux Pumps in Giant LiposomesPark, SooHyun et al. | 2015
- 146
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EPR Accessibility Measurements of the SERCA-PLB Complex using Site-Directed Spin LabelingMartin, Peter D et al. | 2015
- 146a
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Mapping of Sarcolipin Conformational States along the Enzymatic Pathway of SERCADicke, A. A. / Mote, K. R. / Veglia, G. et al. | 2015
- 147
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Exploring Cardiac Calcium ATPase DimerizationBlackwell, Daniel et al. | 2015
- 147
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Using a Live-Cell High-Throughput Time-Resolved FRET Assay to Discover Enzyme ModulatorsLi, Ji et al. | 2015
- 147
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Molecular Dynamics Simulations of Calcium Pump Structural DisorderSmolin, Nikolai et al. | 2015
- 148
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Voltage Dependent Reactions in the Non-Gastric H/K-ATPaseMeyer, Dylan et al. | 2015
- 148a
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Living E. coli is Permeable to Propidium Iodide: A Study by Time-Resolved Second-Harmonic Scattering and Fluorescence MicroscopySharifian Gh, M. / Wilhelm, M. J. / Sheffield, J. B. / Dai, H. L. et al. | 2015
- 149
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Mapping Bioprocessing Dynamics and Noise at the Single Cell Level using MicrofluidicsVasdekis, Andreas E et al. | 2015
- 149
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Wave-Particle Duality in Molecular Machines, Living Cells, and Human BrainsJi, Sungchul et al. | 2015
- 149
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Nanostraws: A Nanofabricated Platform for Delivery of Cell-Impermeable, Synthetic BiomoleculesShieh, Peyton et al. | 2015
- 149a
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Ruthenium(II)Bis(2,2′-Bipyridine) Interactions with Nucleaobases- Models for DNA BindingLarsen, R. W. / Whittington, C. L. / Kemp, M. T. / Word, T. / Woodcock, H. L. et al. | 2015
- 150
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Noise Response of P53 Oscillation against System Size ScalingHe Yue, Chong et al. | 2015
- 151
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Mathematical Modeling of Melanopsin's Light Response in ipRGCs and Hek CellsRobinson, Phyllis R et al. | 2015
- 151a
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V220 Mutants of Ciona Voltage-Sensing Domain Based Genetically Encoded Fluorescent Voltage SensorsRajakumar, D. / Piao, H. h. / Kang, B. E. / Jung, A. / Kim, E. H. / Baker, B. J. et al. | 2015
- 152
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Transition Metal Ion FRET Measurements in Plasma Membrane Sheets Prepared by Deroofing Cultured Mammalian CellsSenning, Eric et al. | 2015
- 152
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Bidirectional Propagation of Action Potential in Giant Axons of Nerve Bundles from Homarus AmericanusWang, Tian et al. | 2015
- 153
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Hypotheses for Hair Cell Ribbon Synapses Probed by a Biomimetic SystemAhn, Kang-Hun et al. | 2015
- 153
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Nonlinear AMPA Sensitivity to Glutamate and Recruitment of NMDA Activity in Dendritic SpinesLoew, Leslie M et al. | 2015
- 153a
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The Energetics of High Frequency Discharge in Electrocytes: A Mathematical Model with Explicit PumpsJoos, B. / Markham, M. R. / Lewis, J. E. / Morris, C. E. et al. | 2015
- 154
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The Mechanism of Inhibition of Necrosis by Humanin Derivatives: A Potential Treatment for Ischemia and Related DiseasesCohen, Aviv et al. | 2015
- 154
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Organization and Dynamics of Nicotinic Acetylcholine Receptor Nanoclusters at the Cell SurfaceBarrantes, Francisco J et al. | 2015
- 154a
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Physical and Topological Constraints on Growth in Human Brain NetworksMaguire, A. M. / Bassett, D. S. / Hermundstad, A. M. et al. | 2015
- 156
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Spatial and Temporal Analyses of Slow Electrical Oscillations Recorded from In-Vitro Neuronal NetworksSuárez, Javier I et al. | 2015
- 156
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Regulation of Coupled β-Cell cAMP DynamicsWilson, cChris et al. | 2015
- 156
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A CHARMM-Compatible Force Field for N- and Aplha-Methylated Peptides with (Phi,Psi) Energy Correction GridVanommeslaeghe, Kenno et al. | 2015
- 157
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The Role of Backbone Dipole Interactions in the Formation of Secondary and Supersecondary StructuresGanesan, Sai et al. | 2015
- 157
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SAMBE: The New Webserver for Predicting the Effect of nssNP on the Protein-Protein Binding Free EnergyPetukh, Marharyta et al. | 2015
- 158
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The Do's and Do Not's of a 100 Million Atom Molecular Dynamics SimulationSingharoy, Abhishek et al. | 2015
- 158
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Minimally-Biased Metadynamics Method to Sample Conformational Ensembles Compatible with Experimental MeasurementsMarinelli, Fabrizio et al. | 2015
- 159
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Towards a Polarizable Force Field for RNA based on the Classical Drude OscillatorLemkul, Justin A et al. | 2015
- 159
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Implementation of Replica-Exchange Umbrella Sampling to the DFTB+ Simulation PackageIto, Shingo et al. | 2015
- 159
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CHARMM Gui Membrane Builder UpdatesCheng, Xi et al. | 2015
- 159
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Experimental and Theoretical Approaches to the Study of Probe Diffusion in Macromolecular SolutionsDonovan, Preston et al. | 2015
- 159a
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A Coupled Two-Dimensional Main Chain Torsional Potential for Protein DynamicsGao, Y. / Li, Y. / Zhang, J. Z. / Mei, Y. et al. | 2015
- 160
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New Developments in the Collective Variables Module: More Flexible, More InteractiveFiorin, Giacomo et al. | 2015
- 160
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Phase Diagram of Lipid-Cholesterol Mixture: Comparison between Different Force FieldsFavela-Rosales, Fernando et al. | 2015
- 160
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Non-Markovian Analyses for Extracting Long-Time Behavior from Molecular Simulation TrajectoriesZuckerman, Daniel M et al. | 2015
- 160
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Molecular Dynamics Simulation of Protein Crystal with Polarized Protein-Specific ChargeZhang, John Z.H et al. | 2015
- 160a
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Parametrization of Halogen Bonds in the CHARMM General Force FieldGutierrez, I. S. et al. | 2015
- 161
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CHARMM-GUI Martini Maker for Coarse-Grained SimulationsIm, Wonpil et al. | 2015
- 162
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Investigating the Kinetics of HSF Binding Using High Throughput Single Molecule ImagingVan Slyke, Alexander L et al. | 2015
- 162
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The Role of Amino Acid Residues Located at the Catalytic Site in the Rotation of Enterococcus Hirae V1-ATPaseMinagawa, Yoshihiro et al. | 2015
- 162
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Membrane Deformation by HER2 Overexpression Disrupts Epithelial IntegrityChung, Inhee et al. | 2015
- 162
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Single-Molecule Fluorescence Microscopy and Tracking of Lipids in Mitochondrial-Like Supported Lipid BilayersRose, Markus et al. | 2015
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Fast and User-Friendly Single-Molecule FRET Microscopy SoftwarePreus, Søren et al. | 2015
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Toolkit for Multi-Conformation Biomolecular Structure Determination by High-Precision FRET and Molecular SimulationsDimura, M. / Kalinin, S. / Peulen, T. / Gohlke, H. / Seidel, C. A. et al. | 2015
- 164
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Bayesian Classification of Mrna and Kinetochore Transport DynamicsBarry, Zachary et al. | 2015
- 165
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Characterization of Fluorescent 3DNA Dendrimers with Fcs and Single Molecule ImagingRuan, Qiaoqiao et al. | 2015
- 165
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Single Molecule Studies of Tau Protein in the Abel TrapWood, Sharla L et al. | 2015
- 165
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Rapid Measurement of Molecular Transport and Interaction Inside Living Cells with Single Plane Illumination MicroscopyHedde, Per Niklas et al. | 2015
- 166
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Bringing Force Probe Molecular Dynamics Simulations Closer to ExperimentsRussek, Andreas et al. | 2015
- 166a
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A Precision Scanning Probe Microscope with Direct Access to the Three Dimensional Tip-Sample Interaction Force VectorSigdel, K. P. / King, G. M. et al. | 2015
- 167
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Atomic Force Microscopy (AFM) Analysis of the Bacterial Polar Protein PopzCaffaro, Carolina E et al. | 2015
- 167
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Fast and Accurate Photodiode-Based Detection of Multiple Trap Optical Tweezers with Crosstalk-EliminationOtt, Dino et al. | 2015
- 167
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Transverse Magnetic Tweezers for Direct DNA Extension MeasurementsVargas, Guillermo et al. | 2015
- 168
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A Novel AFM-Based Technique for Measuring Coupled Phenomena in Cardiac MyocytesRaiteri, Roberto et al. | 2015
- 168
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Effect of Surface Density of Active Sites on Rupture Force Distributions of Single Molecule InteractionsHoffmann, Peter M et al. | 2015
- 169
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Titin is a Spatially Homogenous Linear ExpanderMartonfalvi, Zsolt et al. | 2015
- 169
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Afm Monitoring of Elasticity Changes Accompanying Differentiation Towards Neural CellsDąbrowski, Marcin et al. | 2015
- 170
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Force Spectroscopy of DNA-Ctab AggregatesTompkins, James S et al. | 2015
- 170
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Direct Observation of Titin Immunoglobulin Domain Unfolding-Refolding in Muscle SarcomeresRivas Pardo, Jaime A et al. | 2015
- 171
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Multimodal Imaging Probing Platform Based on Upconverting Rare-Earth Doped Gd2O3 NanocrystalsDoan, Kim Dung T et al. | 2015
- 171
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Investigating Force-Induced Structural Changes in Single Collagen MoleculesForde, Nancy R et al. | 2015