Visual Analysis and Comparison of Multiple Sequence Alignments (Unknown language)

How to get this document?

Commercial Copyright fee: €14.50 Basic fee: €4.00 Total price: €18.50
Academic Copyright fee: €4.50 Basic fee: €2.00 Total price: €6.50

Multiple Sequence Alignments (MSA) of a set of DNA, RNA or protein sequences form the fundamental basis for various biological applications such as evolutionary heritage and protein structure prediction. The quality of an MSA is crucial in order to provide useful and correct results. The analysis of MSAs is, however, still a challenging task since constructing MSAs is an NP hard problem and thus the optimal MSA is usually unknown. Additionally, MSA quality analysis is often completely ignored, especially by non-expert users, due to the lack of tools for the visual comparison and the intuitive quality assessment of alignments. In this paper, we present an interactive visual approach to simultaneously assess the quality of multiple alternative MSAs of the same set of sequences. We provide a direct assessment of the alignment quality using different highlighting techniques in combination with automatic quality measures and editing capabilities. An in-depth evaluation of our approach highlights its benefits for MSA quality assessment.

Table of contents conference proceedings

The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.

Unfolding and Interactive Exploration of Protein Tunnels and their Dynamics
Kolesár, Ivan / Byska, Jan / Parulek, Julius / Hauser, Helwig / Kozlíková, Barbora | 2016
Chameleon - Dynamic Color Mapping for Multi-Scale Structural Biology Models
Waldin, Nicholas / Muzic, Mathieu Le / Waldner, Manuela / Gröller, Eduard / Goodsell, David / Ludovic, Autin / Viola, Ivan | 2016
Illustrative Transitions in Molecular Visualization via Forward and Inverse Abstraction Transform
Sorger, Johannes / Mindek, Peter / Klein, Tobias / Johnson, Graham / Viola, Ivan | 2016
Visual Analysis and Comparison of Multiple Sequence Alignments
Hess, Martin / Jente, Daniel / Wiemeyer, Josef / Hamacher, Kay / Goesele, Michael | 2016
Semi-Automatic Vessel Boundary Detection in Cardiac 4D PC-MRI Data Using FTLE fields
Behrendt, Benjamin / Köhler, Benjamin / Gräfe, Daniel / Grothoff, Matthias / Gutberlet, Matthias / Preim, Bernhard | 2016
Real-Time Guidance and Anatomical Information by Image Projection onto Patients
Edwards, Marc R. / Pop, Serban R. / John, Nigel W. / Ritsos, Panagiotis D. / Avis, Nick | 2016
Volume Visualization Using Principal Component Analysis
Alakkari, Salaheddin / Dingliana, John | 2016
Temporal Interpolation of 4D PC-MRI Blood-flow Measurements Using Bidirectional Physics-based Fluid Simulation
Hoon, Niels H. L. C. de / Jalba, Andrei C. / Eisemann, Elmar / Vilanova, Anna | 2016
A Framework for Fast Initial Exploration of PC-MRI Cardiac Flow
Broos, Arjan J. M. / Hoon, Niels H. L. C. de / Koning, Patrick J. H. de / Geest, Rob J. van der / Vilanova, Anna / Jalba, Andrei C. | 2016
Coherence Maps for Blood Flow Exploration
Englund, Rickard / Ropinski, Timo / Hotz, Ingrid | 2016
Spatio-temporal Visualization of Regional Myocardial Velocities
Sheharyar, Ali / Chitiboi, Teodora / Keller, Eric / Rahman, Ozair / Schnell, Susanne / Markl, Michael / Bouhali, Othmane / Linsen, Lars | 2016
Illustrative PET/CT Visualisation of SIRT-Treated Lung Metastases
Merten, Nico / Glaßer, Sylvia / Lassen-Schmidt, Bianca / Großer, Oliver Stephan / Ricke, Jens / Amthauer, Holger / Preim, Bernhard | 2016
A Feasibility Study on Automated Protein Aggregate Characterization Utilizing a Hybrid Classification Model
Eschweiler, Dennis / Gadermayr, Michael / Unger, Jakob / Nippold, Markus / Falkenburger, Björn / Merhof, Dorit | 2016
PATHONE: From one Thousand Patients to one Cell
Corvò, Alberto / Westenberg, Michel A. / Driel, Marc A. van / Wijk, Jarke J.van | 2016
Recent Advances in MRI and Ultrasound Perfusion Imaging
Jirík, Radovan | 2016
Semi-Immersive 3D Sketching of Vascular Structures for Medical Education
Saalfeld, Patrick / Stojnic, Aleksandar / Preim, Bernhard / Oeltze-Jafra, Steffen | 2016
Sline: Seamless Line Illustration for Interactive Biomedical Visualization
Lichtenberg, Nils / Smit, Noeska / Hansen, Christian / Lawonn, Kai | 2016
Aortic Dissection Maps: Comprehensive Visualization of Aortic Dissections for Risk Assessment
Mistelbauer, Gabriel / Schmidt, Johanna / Sailer, Anna-Margaretha / Bäumler, Kathrin / Walters, Shannon / Fleischmann, Dominik | 2016
How to Evaluate Medical Visualizations on the Example of 3D Aneurysm Surfaces
Glaßer, Sylvia / Saalfeld, Patrick / Berg, Philipp / Merten, Nico / Preim, Bernhard | 2016
Visualization-Guided Evaluation of Simulated Minimally Invasive Cancer Treatment
Voglreiter, Philip / Hofmann, Michael / Ebner, Christoph / Sequeiros, Roberto Blanco / Portugaller, Horst Rupert / Fütterer, Jurgen / Moche, Michael / Steinberger, Markus / Schmalstieg, Dieter | 2016
Monte-Carlo Ray-Tracing for Realistic Interactive Ultrasound Simulation
Mattausch, Oliver / Goksel, Orcun | 2016
Graxels: Information Rich Primitives for the Visualization of Time-Dependent Spatial Data
Stoppel, Sergej / Hodneland, Erlend / Hauser, Helwig / Bruckner, Stefan | 2016
Visual Analytics for the Exploration and Assessment of Segmentation Errors
Raidou, Renata G. / Marcelis, Freek J. J. / Breeuwer, Marcel / Gröller, Eduard / Vilanova, Anna / Wetering, Huub M. M. van de | 2016