Imaging the Vascular Network of the Human Spleen from Immunostained Serial Sections (English)

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The spleen is one of the organs, where the micro-structure and the function on that level are not completely understood. It was for example only recently found that is has an open circulation, which distinguishes it from all other organs. Imaging the complete vascular network from the arteries to open-ended capillaries would greatly facilitate research in this area. The structure of such tissue is best uncovered using immunehistological staining. This can however only be applied to thin tissue sections and larger structures span several slices. Due to the deformation induced when cutting the specimen, standard registration algorithms cannot be used to merge the images into a volume. We propose a specialized matching algorithm to robustly determine corresponding regions in the images. After a rigid alignment of the scans, we use a cubic B-spline to deform and align the images. During this process we minimize the total deformation to produce as accurate results as possible.

Table of contents conference proceedings

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Inlier Detection in Thermal Sensitive Images
Zadicario, Eyal / Carmi, N. / Ju, Tao / Cohen-Or, Daniel | 2014
RegistrationShop: An Interactive 3D Medical Volume Registration System
Smit, Noeska N. / Haneveld, Berend Klein / Staring, Marius / Eisemann, Elmar / Botha, Charl P. / Vilanova, Anna | 2014
Misalignment Correction in Open Cone-Beam CT
Wieckowski, Adam / Stopp, Fabian / Käseberg, Marc / Keeve, Erwin | 2014
Deriving Anatomical Context from 4D Ultrasound
Müller, Markus / Helljesen, Linn E. S. / Prevost, Raphael / Viola, Ivan / Nylund, Kim / Gilja, Odd Helge / Navab, Nassir / Wein, Wolfgang | 2014
Interactive Labeling of Toponome Data
Oeltze-Jafra, Steffen / Pieper, Franz / Hillert, Reyk / Preim, Bernhard / Schubert, Walter | 2014
Imaging the Vascular Network of the Human Spleen from Immunostained Serial Sections
Ulrich, Christine / Lobachev, Oleg / Steiniger, Birte / Guthe, Michael | 2014
Survey of Labeling Techniques in Medical Visualizations
Oeltze-Jafra, Steffen / Preim, Bernhard | 2014
Towards Clinical Deployment of Automated Anatomical Regions-Of-Interest
Lindholm, Stefan / Forsberg, Daniel / Ynnerman, Anders / Knutsson, Hans / Andersson, Mats / Lundström, Claes | 2014
The iCoCooN: Integration of Cobweb Charts with Parallel Coordinates for Visual Analysis of DCE-MRI Modeling Variations
Raidou, Renata G. / Breeuwer, Marcel / Vilanova, Anna / Heide, U. A. van der / Houdt, P. J. van | 2014
Robust Cardiac Function Assessment in 4D PC-MRI Data
Köhler, Benjamin / Preim, Uta / Gutberlet, Matthias / Fischbach, Katharina / Preim, Bernhard | 2014
A Survey on Visualizing Magnetic Resonance Spectroscopy Data
Nunes, Miguel / Laruelo, Andrea / Ken, SoleaKhena / Laprie, Anne / Bühler, Katja | 2014
Membrane Mapping: Combining Mesoscopic and Molecular Cell Visualization
Waltemate, Thomas / Sommer, Björn / Botsch, Mario | 2014
Evaluation of Transfer Function Methods in Direct Volume Rendering of the Blood Vessel Lumen
Läthén, Gunnar / Lindholm, Stefan / Lenz, Reiner / Borga, Magnus | 2014
Visibility-Driven Processing of Streaming Volume Data
Solteszova, Veronika / Birkeland, Asmund / Viola, Ivan / Bruckner, Stefan | 2014
A Comparative User Study of a 2D and an Autostereoscopic 3D Display for a Tympanoplastic Surgery
Baer, Alexandra / Huebler, Antje / Saalfeld, Patrick / Cunningham, Douglas / Preim, Bernhard | 2014
Extracting and Visualizing Uncertainties in Segmentations from 3D Medical Data
Faltin, Peter / Chaisaowong, Kraisorn / Kraus, Thomas / Merhof, Dorit | 2014
Real-Time Dense Nucleus Selection from Confocal Data
Wan, Yong / Otsuna, Hideo / Kwan, K. M. / Hansen, Charles | 2014
Visual and Quantitative Analysis of Higher Order Arborization Overlaps for Neural Circuit Research
Swoboda, Nicolas / Moosburner, Judith / Bruckner, Stefan / Yu, Jai Y. / Dickson, Barry J. / Bühler, Katja | 2014
Personalized X-ray Reconstruction of the Proximal Femur via a New Control Point-based 2D-3D Registration and Residual Complexity Minimization
Yu, Weimin / Zheng, Guoyan | 2014
Uncertainty-aware Ensemble of Classifiers for Segmenting Brain MRI Data
Al-Taie, Ahmed / Hahn, Horst K. / Linsen, Lars | 2014
Visualizing Movements of Protein Tunnels in Molecular Dynamics Simulations
Kozlíková, Barbora / Jurcík, Adam / Byka, Jan / Strnad, Ondrej / Sochor, Jirí | 2014
Interactive Visualization of Muscle Activity During Limb Movements: Towards Enhanced Anatomy Learning
Bauer, Armelle / Paclet, Florent / Cahouet, Violaine / Dicko, Ali-Hamadi / Palombi, Olivier / Faure, François / Troccaz, Jocelyne | 2014