The biocompatibility of silk fibroin films containing sulfonated silk fibroin (English)

Journal of Biomedical Materials Research. Part B - Applied Biomaterials
; 2006
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Sulfonation reaction may be an effective method for preparation of heparin-like materials. However, no sulfonated polymer based on protein backbone was used for improving the blood compatibility of biomaterials. In the study, the biocompatibility of new kind of composite materials films obtained by blending silk fibroin (SF) with sulfonated silk fibroin (SSF) was evaluated. The anticoagulant activity was characterized with prothrombin time (PT), activated partial thromboplastin time (APTT), and thrombin time (TT), which all increased remarkably, the clot times exceeded the measurement limit of clot detection instrument. Its platelet adhesion was also investigated as another parameter of blood compatibility. The cell compatibility of composite films was evaluated through cell morphologies on the films and cell viability by methyl thiazolyl tetrazolium (MTT) assay. Tensile strength and elongation at break of the composite films reached to 44.6 MPa and 50.3 %, respectively. All these results indicated that SF/SSF composite film was a potential material for blood-contact materials and tissue engineering matrix.

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Table of contents – Volume 78B, Issue 1

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Tables of content are generated automatically and are based on records of articles contained that are available in the TIB-Portal index. Due to missing records of articles, the volume display may be incomplete, even though the whole journal is available at TIB.

1
Changes in color and translucency of porcelain‐repairing resin composites after thermocycling
Choi, Mi‐Sook / Lee, Yong‐Keun / Lim, Bum‐Soon / Rhee, Sang‐Hoon / Yang, Hyeong‐Cheol / Lim, Young‐Jun | 2006
7
A novel method to obtain microtensile specimens minimizing cut flaws
Sadek, Fernanda Tranchesi / Monticelli, Francesca / Muench, Antonio / Ferrari, Marco / Cardoso, Paulo Eduardo Capel | 2006
15
Stair ascent kinematics affect UHMWPE wear and damage in total knee replacements
Cottrell, Jocelyn M. / Babalola, Omotunde / Furman, Bridgette S. / Wright, Timothy M. | 2006
20
Oxidation and oxidation potential in contemporary packaging for polyethylene total joint replacement components
Costa, Luigi / Bracco, Pierangiola / Brach del Prever, Elena Maria / Kurtz, Steven M. / Gallinaro, Paolo | 2006
27
Nanoindentation of dental composites
Drummond, James L. | 2006
35
Healing pattern of bone defects covered by different membrane types—A histologic study in the porcine mandible
Strietzel, Frank P. / Khongkhunthian, Pathawee / Khattiya, Rutch / Patchanee, Prapas / Reichart, Peter A. | 2006
35
Healing pattern of bone defects covered by different membrane types - A histologie study in the porcine mandible
Strietzel, Frank P. / Khongkhunthian, Pathawee / Khattiya, Rutch / Patchanee, Prapas / Reichart, Peter A. | 2006
47
Porous akermanite scaffolds for bone tissue engineering: Preparation, characterization, and in vitro studies
Wu, Chengtie / Chang, Jiang / Zhai, Wanyin / Ni, Siyu / Wang, Junying | 2006
56
Preparation and drug release characteristics of pingyangmycin‐loaded dextran cross‐linked gelatin microspheres for embolization therapy
Wu, Hong / Zhang, Zhenxi / Wu, Daocheng / Zhao, Hongping / Yu, Kaitao / Hou, Zhenqing | 2006
63
A mechanism on why slower polymerization of a dental composite produces lower contraction stress
Feng, L. / Suh, B. I. | 2006
70
Contemporary alumina‐on‐alumina total hip arthroplasty performed in patients younger than forty years: A 5‐year minimum follow‐up study
Yoo, Jeong Joon / Kim, Young‐Min / Yoon, Kang Sup / Koo, Kyung‐Hoi / Kim, Jong Won / Nam, Kwang Woo / Kim, Hee Joong | 2006
76
Advanced nanocomposite materials for orthopaedic applications. I. A long‐term in vitro wear study of zirconia‐toughened alumina
Affatato, S. / Torrecillas, R. / Taddei, P. / Rocchi, M. / Fagnano, C. / Ciapetti, G. / Toni, A. | 2006
83
Augmentation of osteoporotic bone: Effect of pulsed jet‐lavage on injection forces, cement distribution, and push‐out strength of implants
Gisep, A. / Curtis, R. / Flütsch, S. / Suhm, N. | 2006
89
The biocompatibility of silk fibroin films containing sulfonated silk fibroin
Ma, Xilan / Cao, Chuanbao / Zhu, Hesun | 2006
97
Characterization of human primary osteoblast response on bioactive glass (BaG 13–93)‐ coated poly‐L,DL‐lactide (SR‐PLA70) surface in vitro
Ruuttila, P. / Niiranen, H. / Kellomäki, M. / Törmälä, P. / Konttinen, Y. T. / Hukkanen, M. | 2006
105
In vitro wear of resin‐based materials—Simultaneous corrosive and abrasive wear
Correr, Gisele Maria / Alonso, Roberta Caroline Bruschi / Sobrinho, Lourenço Correr / Puppin‐Rontani, Regina Maria / Ferracane, Jack Liborio | 2006
115
Effect of light‐cure time of adhesive resin on the thickness of the oxygen‐inhibited layer and the microtensile bond strength to dentin
Kim, Jong‐Soon / Choi, Yong‐Hoon / Cho, Byeong‐Hoon / Son, Ho‐Hyun / Lee, In‐Bog / Um, Chung‐Moon / Kim, Chang‐Keun | 2006
124
Three‐dimensional direct writing of B35 neuronal cells
Patz, T. M. / Doraiswamy, A. / Narayan, R. J. / He, W. / Zhong, Y. / Bellamkonda, R. / Modi, R. / Chrisey, D. B. | 2006
131
Cytotoxic effects of dental desensitizers on human gingival fibroblasts
Sengun, A. / Buyukbas, S. / Hakki, S. S. | 2006
138
Three‐dimensional printing of porous polyethylene structure using water‐based binders
Suwanprateeb, J. / Chumnanklang, R. | 2006
146
Characterization of functionally graded hydroxyapatite/titanium composite coatings plasma‐sprayed on Ti alloys
Chen, Chun‐Cheng / Huang, Tsui‐Hsien / Kao, Chia‐Tze / Ding, Shinn‐Jyh | 2006
153
An in vitro optimized injectable calcium phosphate cement for augmenting screw fixation in osteopenic goats
Leung, Kwok Sui / Siu, Wing Sum / Li, Siu Fai / Qin, Ling / Cheung, Wing Hoi / Tam, Kam Fai / Lui, Pauline Po Yee | 2006
161
Effect of an acidulated fluoride etchant on bonding between titanium and two luting materials
Yang, Lei / Taira, Yohsuke / Atsuta, Mitsuru | 2006
167
The nature of platinum in silicones for biomedical and healthcare use
Lambert, James M. | 2006
181
Fatigue debonding of the roughened stem–cement interface: Effects of surface roughness and stem heating conditions
Damron, Leatha A. / Kim, Do‐Gyoon / Mann, Kenneth A. | 2006
189
Comparison of two radio‐frequency plasma sterilization processes using microspot evaluation of microbial inactivation
Lassen, Klaus S. / Johansen, Jens E. / Grün, Reinar | 2006
196
Wear and fatigue behavior of nano‐structured dental resin composites
Turssi, Cecilia P. / Ferracane, Jack L. / Ferracane, Lucas L. | 2006
204
Hydrogen absorption of titanium and nickel‐titanium alloys during long‐term immersion in neutral fluoride solution
Yokoyama, Ken'ichi / Ogawa, Toshio / Asaoka, Kenzo / Sakai, Jun'ichi | 2006
211
In vivo performance of two different hydroxyapatite coatings on titanium prepared by discharging in electrolytes
Yamamoto, Hiroki / Shibata, Yo / Tachikawa, Tetsuhiko / Miyazaki, Takashi | 2006
V
Announcement
| 2006

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