Data sources in the TIB-Portal   Search help

Our Tip: Log in for optimal use of all functions in the TIB Portal!

Piperine Inhibits Gastric Emptying and Gastrointestinal Transit in Rats and Mice (English)

In: Planta Medica   ;  67 ,  02  ;  176-179  ;  2001

How to get this document?

Check access
Download
Commercial Copyright fee: €47.00 Basic fee: €4.00 Total price: €51.00
Academic Copyright fee: €47.00 Basic fee: €2.00 Total price: €49.00

Piperine (1), an alkaloid of black and long peppers, inhibited gastric emptying (GE) of solids/liquids in rats and gastrointestinal transit (GT) in mice in a dose and time dependent manner. Compound 1 significantly inhibited GE of solids and GT at the doses extrapolated from humans (1 mg/kg and 1.3 mg/kg P.O. in rats and mice, respectively). However, at the same dose the effect was insignificant for GE of liquids. One week oral treatment of 1 mg/kg and 1.3 mg/kg in rats and mice, respectively, did not produce a significant change in activity as compared to single dose administration. GE inhibitory activity of 1 is independent of gastric acid and pepsin secretion.

  • Title:
    Piperine Inhibits Gastric Emptying and Gastrointestinal Transit in Rats and Mice
  • Author / Creator:
    Bajad, Sunil / Bedi, K. L. / Singla, A. K. / Johri, R. K.
  • Published in:
    Planta Medica ; 67 ; 02 ; 176-179
  • Publisher:
    • New search for:
  • Publication date:
    2001-01-01
  • Size:
    4 pages
  • ISSN:
    0032-0943, 1439-0221
  • DOI:
    https://doi.org/10.1055/s-2001-11505
  • Type of media:
    Article (Journal)
  • Type of material:
    Electronic Resource
  • Language:
    English
  • Source:
    Thieme Verlag
  • Export:
  • Share:
  • Citation:
  • ORKG:

Table of contents – Volume 67, Issue 02

Show all volumes and issues

The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.

103
A Sesquiterpene Lactone, Costunolide, from Magnolia grandiflora Inhibits NF-κB by Targeting IκB Phosphorylation
Koo, Tae Hyeon / Lee, Jeong-Hyung / Park, Yun Joo / Hong, Young-Soo / Kim, Hang Sub / Kim, Kyu-Won / Lee, Jung Joon | 2001
108
Influence of Natural and Synthetic Compounds on Cell Surface Expression of Cell Adhesion Molecules, ICAM-1 and VCAM-1
Tanaka, Shigeo / Sakata, Yoichi / Morimoto, Katsushi / Tambe, Yukihiro / Watanabe, Yoshihiko / Honda, Gisho / Tabata, Mamoru / Oshima, Tikashi / Masuda, Toru / Umezawa, Toshiaki et al. | 2001
114
Structure-Antinociceptive Activity Studies of Incarvillateine, a Monoterpene Alkaloid from Incarvillea sinensis
Nakamura, Motoyuki / Chi, Yu-Ming / Yan, Wen-Mei / Yonezawa, Akihiko / Nakasugi, Yumiko / Yoshizawa, Toyokichi / Hashimoto, Fumio / Kinjo, Junei / Nohara, Toshihiro / Sakurada, Shinobu | 2001
118
Kalopanaxsaponin A is a Basic Saponin Structure for the Anti-Tumor Activity of Hederagenin Monodesmosides
Park, Hee-Juhn / Kwon, Sang-Hyuk / Lee, Joo-Han / Lee, Kyou-Heung / Miyamoto, Ken-ichi / Lee, Kyung-Tae | 2001
122
Nitric Oxide is Involved in the Immunomodulating Activities of Acidic Polysaccharide from Panax ginseng
Park, Kyeong Mee / Kim, Young Sook / Jeong, Tae Cheon / Joe, Cheol O. / Shin, Han Jae / Lee, You Hui / Nam, Ki Yeul / Park, Jong Dae | 2001
127
Mutagenicity of Natural Anthraquinones from Rubia tinctorum in the Drosophila Wing Spot Test
Marec, František / Kollárová, Ivana / Jegorov, Alexandr | 2001
132
Inhibitory Effect of Baicalein, a Flavonoid in Scutellaria Root, on Eotaxin Production by Human Dermal Fibroblasts
Nakajima, Toshiharu / Imanishi, Masako / Yamamoto, Kazuhiko / Cyong, Jong-Chol / Hirai, Koichi | 2001
136
Anticonvulsant Properties and Bio-Guided Isolation of Palmitone from Leaves of Annona diversifolia1
González-Trujano, María Eva / Navarrete, Andrés / Reyes, Benito / Cedillo-Portugal, Ernestina / Hong, Enrique | 2001
142
Neuroprotective Effects in Gerbils of Spiramine T from Spiraea japonica var. acuta
Li, Ling / Nie, Jinlei / Shen, Zhiqiang / Wu, Wanling / Chen, Zhihe / Hao, Xiaojiang | 2001
146
In Vitro Propagation of Withania somnifera and Isolation of Withanolides with Immunosuppressive Activity
Furmanowa, Mirosława / Gajdzis-Kuls, Dorota / Ruszkowska, Joanna / Czarnocki, Zbigniew / Obidoska, Grażyna / Sadowska, Ałła / Rani, R. / Upadhyay, Shakti N. | 2001
150
Growth and Production of Camptothecin by Cell Suspension Cultures of Nothapodytes foetida
Fulzele*, Devanand P. / Satdive, Ramesh K. / Pol, B. B. | 2001
153
A New Diterpenoid with Antispasmodic Activity from Salvia cinnabarina
Romussi, Giovanni / Ciarallo, Giovanni / Bisio, Angela / Fontana, Nadia / De Simone, Francesco / De Tommasi, Nunziatina / Mascolo, Nicola / Pinto, Luisa | 2001
156
Pheophorbide A from Solanum diflorum Interferes with NF-κB Activation
Heinrich, Michael / Bork, Peter M. / Schmitz, M. Lienhard / Rimpler, Horst / Frei, Barbara / Sticher, Otto | 2001
158
Inhibition of Xanthine and Monoamine Oxidases by Stilbenoids from Veratrum taliense
Zhou, C. X. / Kong, L. D. / Ye, W. C. / Cheng, Christopher H. K. / Tan, R. X. | 2001
161
In Vitro Anti-Helicobacter pylori Activity of Irisolidone Isolated from the Flowers and Rhizomes of Pueraria thunbergiana
Bae, Eun-Ah / Han, Myung Joo / Kim, Dong-Hyun | 2001
164
In Vitro Activity of a Solanum tuberosum Extract against Mammary Carcinoma Cells
De Lorenzo, Mariana S. / Menna, Pablo Lorenzano / Alonso, Daniel F. / Gomez*, Daniel E. | 2001
166
Lignans as Anti-Tumor-Promoter from the Seeds of Hernandia ovigera
Ito, Chihiro / Itoigawa, Masataka / Ogata, Masakazu / Mou, Xiao Yang / Tokuda, Harukuni / Nishino, Hoyoku / Furukawa, Hiroshi | 2001
168
Essential Oils and Hexane Extracts from Leaves and Fruits of Cistus monspeliensis. Cytotoxic Activity of ent-13-epi-Manoyl Oxide and its Isomers
Angelopoulou, Dimitra / Demetzos, Costas / Dimas, Costas / Perdetzoglou, Dimitrios / Loukis, Anargyros | 2001
172
Cnidicin, a Coumarin, from the Root of Angelica koreana, Inhibits the Degranulation of Mast Cell and the NO Generation in RAW 264.7 Cells
Ryu, Shi Yong / Kou, Na Youn / Choi, Hong Seok / Ryu, Hyun / Kim, Tae Sung / Kim, Kyeong Man | 2001
174
Local Anaesthetic Activity of (+)- and (-)-Menthol
Galeotti, Nicoletta / Ghelardini, Carla / Di Cesare Mannelli, Lorenzo / Mazzanti, Gabriela / Baghiroli, Laura / Bartolini, Alessandro | 2001
176
Piperine Inhibits Gastric Emptying and Gastrointestinal Transit in Rats and Mice
Bajad, Sunil / Bedi, K. L. / Singla, A. K. / Johri, R. K. | 2001
179
Modulatory Effect of Aliphatic Acid Amides from Zanthoxylum piperitum on Isolated Gastrointestinal Tract
Hashimoto, Kazunori / Satoh, Kazuko / Kase, Yoshio / Ishige, Atsushi / Kubo, Masayoshi / Sasaki, Hiroshi / Nishikawa, Shigeto / Kurosawa, Susumu / Yakabi, Koji / Nakamura, Takashi | 2001
181
In Vitro Plantlet Regeneration in Panax sikkimensis
Mathur*, Archana / Mathur, Ajay Kumar / Gangwar, Anita | 2001
183
Authentic Identification of Stigma Croci (Stigma of Crocus sativus) from its Adulterants by Molecular Genetic Analysis
Ma, X. Q. / Zhu, D. Y. / Li, S. P. / Dong, T. T. X. / Tsim, K. W. K. | 2001
186
Dihydrochalcones from Piper longicaudatum
Joshi, A. S. / Li, X.-C. / Nimrod, A. C. / ElSohly, H. N. / Walker, L. A. / Clark, A. M. | 2001
189
Isoquinoline Alkaloids from Thalictrum delavayi
Li, Mai / Chen, Xin / Tang, Qin-Mei / Zhang*, Jin-Sheng | 2001
191
Crinane and Lycorane Type Alkaloids from Zephyranthes citrina
Herrera, María R. / Machocho, Alex K. / Brun, Reto / Viladomat, Francesc / Codina, Carles / Bastida, Jaume | 2001
194
Acutudaurin from Cultured Roots of Menispermum dauricum
Furumoto, Toshio / Sugimoto, Yukihiro | 2001
196
Steroidal Saponins from Tribulus terrestris
Cai, Lifeng / Wu, Yijie / Zhang, Jianguo / Pei, Fengkui / Xu, Yajuan / Xie, Shengxu / Xu, Dongming | 2001

How to get this document?

Check access
Download
Commercial Copyright fee: €47.00 Basic fee: €4.00 Total price: €51.00
Academic Copyright fee: €47.00 Basic fee: €2.00 Total price: €49.00
Feedback