A combination of nonoperative treatment modalities used for treatment of keloids (English)

In: Dermatologic Therapy   ;  27 ,  1  ;  48-51  ;  2014

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Keloid is one abnormal wound healing that occurs commonly in predisposed individuals. Many treatment modalities have been tried, either alone or in variety, including surgical removal, laser therapy, radiation therapy, silicone cream or gel application, cryosurgery, and intralesional injection of various agents. These treatment options have been practiced with largely transient and limited success. In the present study, the present authors prospectively assessed the efficacy of combination methods of the treatment of recalcitrant keloid. One hundred fifty‐one sites of keloids in 122 patients were chosen, age of patients varied between 15 and 60 years, size of scar more than 2 cm2 with pain, itch, or other discomfort, and duration of more than 2 years. Keloids were treated with combination methods of lasers and 32P radiation on originating scars. One hundred eleven of 151 evaluated sites scored “excellence” and 40 belonged to “effectiveness”. These patients demonstrated local control and have remained free of local recurrence for more than 2 years. In addition, there were only 21 and 32 sites with pigmentation and depigmentation, respectively. Over the past 5 years, we established a treatment protocol combining laser with 32P‐patch contact brachyradiotherapy, which represents a safe and effective option in the treatment of keloids.

Table of contents – Volume 27, Issue 1

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The clinical significance of drug interactions between dermatological and psychoactive medications
Frew, John W. | 2014
Itch in familial lichen amyloidosis: effective treatment with amitriptyline in two cases
Yew, Yik Weng / Tey, Hong Liang | 2014
Desferrioxamine treatment of porphyria cutanea tarda in a patient with HIV and chronic renal failure
Vasconcelos, Pedro / Luz‐Rodrigues, H. / Santos, Carla / Filipe, Paulo | 2014
Extramammary Paget disease successfully treated with topical imiquimod 5% and tazarotene
Frances, Laura / Pascual, Jose C. / Leiva‐Salinas, Maria / Betlloch, Isabel | 2014
Efficacy of treatment with oral alitretinoin in patient suffering from lichen simplex chronicus and severe atopic dermatitis of hands
D'Erme, Angelo Massimiliano / Milanesi, Nicola / Agnoletti, Arianna Fay / Maio, Vincenza / Massi, Daniela / Gola, Massimo | 2014
Sequential treatment with intradermal incision (intracision) and 2,940‐nm Er:YAG laser for chicken pox scars
Lee, Sang Ju / Kim, Young Koo / Choi, Sun Young / Park, Kui Young / Seo, Seong Jun | 2014
Streptococcal infections of skin and PANDAS
Carelli, Rosanna / Pallanti, Stefano | 2014
Pulsed dye laser treatment for facial flat warts
Grillo, E. / Boixeda, P. / Ballester, A. / Miguel‐Morrondo, A. / Truchuelo, T. / Jaén, P. | 2014
Successful treatment of angiolymphoid hyperplasia with eosinophilia and Kimura's disease in the same patient with surgery
Jun, Ren / Liu, Xiao‐kun / Zeng, Kang | 2014
Deep vein thrombosis and lung cancer in a patient with psoriasis under anti‐tumor necrosis factor treatment: a case study
Tatarkova, Iva / Cetkovska, Petra | 2014
Randomized controlled trial comparing photodynamic therapy based on methylene blue dye and fluconazole for toenail onychomycosis
Figueiredo Souza, L. W. / Souza, S. V. T. / Botelho, A. C. C. | 2014
A combination of nonoperative treatment modalities used for treatment of keloids
Yan, Daojin / Zhao, Bocheng / Yang, Haiping / Zhu, Bin / Wang, Jing | 2014
Multiple cutaneous malignancies and cherry hemangiomas in a vitiligo patient treated with topical nitrogen mustard
Zhu, Li‐li / Zheng, Song / Wei, Huachen / Hong, Yu‐xiao / Zhang, Lan / Zhang, Li / Chen, Hong‐Duo / Gao, Xing‐Hua | 2014
Low‐dose methotrexate – a therapeutical kick in TNF‐alpha antagonist treatment for recalcitrant psoriasis vulgaris
Wilsmann‐Theis, Dagmar / Fronhoffs, Kristina / Ehler, Lin‐Kristin / Wenzel, Joerg / Bieber, Thomas / Klingmueller, Karin | 2014
Epidermolysis bullosa pruriginosa showing good response to low‐dose thalidomide – a report of two cases
Ranugha, P. S. S. / Mohanan, S. / Chandrashekar, L. / Basu, D. / Thappa, D. M. / Rajesh, N. G. | 2014
Issue Information
| 2014