Special considerations in safety pharmacology: Biologicals (Englisch)

In: TOXICOLOGY LETTERS   ;  189 ;  S9  ;  2009
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  • Titel:
    Special considerations in safety pharmacology: Biologicals
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    Elsevier Science B.V., Amsterdam.
  • Erscheinungsjahr:
    2009
  • Format / Umfang:
    S9
  • ISSN:
  • Medientyp:
    Aufsatz (Zeitschrift)
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    Print
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    Englisch
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1
Trends in research activity in toxicology and by toxicologists in seven European countries
Miro, O. / Montori, E. / Ramos, X. / Galicia, M. / Nogue, S. | 2009
5
Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine
Liu, W. b. / Liu, J. y. / Ao, L. / Zhou, Z. y. / Zhou, Y. h. / Cui, Z. h. / Yang, H. / Cao, J. | 2009
14
Effects of in utero through lactational exposure to dicyclohexyl phthalate and p,pprime-DDE in Sprague-Dawley rats
Yamasaki, K. / Okuda, H. / Takeuchi, T. / Minobe, Y. | 2009
21
Pro-apoptotic effects of nivalenol and deoxynivalenol trichothecenes in J774A.1 murine macrophages
Marzocco, S. / Russo, R. / Bianco, G. / Autore, G. / Severino, L. | 2009
27
Dehydroascorbate protection against dioxin-induced toxicity in the b-cell line INS-1E
Martino, L. / Novelli, M. / Masini, M. / Chimenti, D. / Piaggi, S. / Masiello, P. / De Tata, V. | 2009
35
Convulsant effect of diphenyl diselenide in rats and mice and its relationship to plasma levels
Prigol, M. / Schumacher, R. F. / WayneNogueira, C. / Zeni, G. | 2009
40
Fetal and neonatal exposure to three typical environmental chemicals with different mechanisms of action: Mixed exposure to phenol, phthalate, and dioxin cancels the effects of sole exposure on mouse midbrain dopaminergic nuclei
Tanida, T. / Warita, K. / Ishihara, K. / Fukui, S. / Mitsuhashi, T. / Sugawara, T. / Tabuchi, Y. / Nanmori, T. / Qi, W. M. / Inamoto, T. | 2009
48
Acute renal failure enhances the antidotal activity of pralidoxime towards paraoxon-induced respiratory toxicity
Kayouka, M. / Houze, P. / Debray, M. / Baud, F. J. | 2009
57
The Aryl-hydrocarbon receptor does not require the p23 co-chaperone for ligand binding and target gene expression in vivo
Flaveny, C. / Perdew, G. H. / Miller, C. A. | 2009
63
Exposure to an 890-MHz mobile phone-like signal and serum levels of S100B and transthyretin in volunteers
Soderqvist, F. / Carlberg, M. / Hansson Mild, K. / Hardell, L. | 2009
67
Effects of plasticizers and their mixtures on estrogen receptor and thyroid hormone functions
Ghisari, M. / Bonefeld-Jorgensen, E. C. | 2009
78
Neurobehavioral effects of tetrabromobisphenol A, a brominated flame retardant, in mice
Nakajima, A. / Saigusa, D. / Tetsu, N. / Yamakuni, T. / Tomioka, Y. / Hishinuma, T. | 2009
84
Potent inhibition of human cytochrome P450 1B1 by tetramethoxystilbene
Chun, Y. J. / Oh, Y. K. / Kim, B. J. / Kim, D. / Kim, S. S. / Choi, H. K. / Kim, M. Y. | 2009
91
PCB126 enhanced the genotoxicity of BaP in HepG2 cells by modulating metabolic enzyme and DNA repair activities
Wei, W. / Zhang, C. / Liu, A. L. / Xie, S. H. / Chen, X. M. / Lu, W. Q. | 2009
96
Induction of gene pattern changes associated with dysfunctional lipid metabolism induced by dietary fat and exposure to a persistent organic pollutant
Arzuaga, X. / Ren, N. / Stromberg, A. / Black, E. P. / Arsenescu, V. / Cassis, L. A. / Majkova, Z. / Toborek, M. / Hennig, B. | 2009
102
Uptake of phenoxyacetic acid derivatives into Caco-2 cells by the monocarboxylic acid transporters
Kimura, O. / Tsukagoshi, K. / Endo, T. | 2009
110
Effects of oximes on mitochondrial oxidase activity
Sakurada, K. / Ikegaya, H. / Ohta, H. / Fukushima, H. / Akutsu, T. / Watanabe, K. | 2009
115
Yohimbine prevents the effect of morphine on the redox status of neuroblastomaxglioma NG108-15 cells
Polanco, M. J. / Alguacil, L. F. / Albella, B. / Segovia, J. C. / Gonzalez-Martin, C. | 2009
121
Interactions of deoxynivalenol and lipopolysaccharides on cytotoxicity protein synthesis and metabolism of DON in porcine hepatocytes and Kupffer cell enriched hepatocyte cultures
Doll, S. / Schrickx, J. A. / Valenta, H. / Danicke, S. / Fink-Gremmels, J. | 2009
130
Characterization of chromatin instabilities induced by glyphosate, terbuthylazine and carbofuran using cytome FISH assay
Mladinic, M. / Perkovic, P. / Zeljezic, D. | 2009
138
"ToxRTool", a new tool to assess the reliability of toxicological data
Schneider, K. / Schwarz, M. / Burkholder, I. / Kopp-Schneider, A. / Edler, L. / Kinsner-Ovaskainen, A. / Hartung, T. / Hoffmann, S. | 2009
145
1,3-Dinitrobenzene induces apoptosis in TM4 mouse Sertoli cells: Involvement of the c-Jun N-terminal kinase (JNK) MAPK pathway
Lee, Y. S. / Yoon, H. J. / Oh, J. H. / Park, H. J. / Lee, E. H. / Song, C. W. / Yoon, S. | 2009
152
Acute methamphetamine exposure inhibits cardiac contractile function
Turdi, S. / Schamber, R. M. / Roe, N. D. / Chew, H. G. / Culver, B. / Ren, J. | 2009
159
Drug-induced hepatotoxicity test using g-glutamylcysteine synthetase knockdown rat
Morita, M. / Akai, S. / Hosomi, H. / Tsuneyama, K. / Nakajima, M. / Yokoi, T. | 2009
166
rBTI induces apoptosis in human solid tumor cell lines by loss in mitochondrial transmembrane potential and caspase activation
Li, Y. Y. / Zhang, Z. / Wang, Z. H. / Wang, H. W. / Zhang, L. / Zhu, L. | 2009
177
The impact of size on tissue distribution and elimination by single intravenous injection of silica nanoparticles
Cho, M. / Cho, W. S. / Choi, M. / Kim, S. J. / Han, B. S. / Kim, S. H. / Kim, H. O. / Sheen, Y. Y. / Jeong, J. | 2009
184
Ontogenic expression of hepatic Ahr mRNA is associated with histone H3K4 di-methylation during mouse liver development
Cui, Y. J. / Yeager, R. L. / Zhong, X. b. / Klaassen, C. D. | 2009
191
Inhibitor of differentiation 1 (Id1) expression attenuates the degree of TiO2-induced cytotoxicity in H1299 non-small cell lung cancer cells
Lee, Y. S. / Yoon, S. / Yoon, H. J. / Lee, K. / Yoon, H. K. / Lee, J. H. / Song, C. W. | 2009
200
l-Arginine normalizes NOS activity and zinc-MT homeostasis in the kidney of mice chronically exposed to inorganic mercury
Piacenza, F. / Malavolta, M. / Cipriano, C. / Costarelli, L. / Giacconi, R. / Muti, E. / Tesei, S. / Pierpaoli, S. / Basso, A. / Bracci, M. | 2009
206
Lung toxicity induced by intratracheal instillation of size-fractionated tire particles
Mantecca, P. / Sancini, G. / Moschini, E. / Farina, F. / Gualtieri, M. / Rohr, A. / Miserocchi, G. / Palestini, P. / Camatini, M. | 2009
215
Neurofilament isoform alterations in the rat cerebellum following cytosine arabinoside administration
Koros, C. / Kitraki, E. | 2009
219
Mixed-model QSAR at the human mineralocorticoid receptor: Predicting binding mode and affinity of anabolic steroids
Peristera, O. / Spreafico, M. / Smiesko, M. / Ernst, B. / Vedani, A. | 2009
225
Development and characterization of a rat model of chronic obstructive pulmonary disease (COPD) induced by sidestream cigarette smoke
Zheng, H. / Liu, Y. / Huang, T. / Fang, Z. / Li, G. / He, S. | 2009
235
BC nanofibres: In vitro study of genotoxicity and cell proliferation
Moreira, S. / Silva, N. B. / Almeida-Lima, J. / Rocha, H. A. / Medeiros, S. R. / Alves, C. / Gama, F. M. | 2009
242
Changes in serum hepcidin levels in acute iron intoxication in a rat model
Ben-Assa, E. / Youngster, I. / Kozer, E. / Abu-Kishk, I. / Bar-Haim, A. / Bar-Oz, B. / Berkovitch, M. | 2009
248
Bisphenol A downregulates CYP19 transcription in JEG-3 cells
Huang, H. / Leung, L. K. | 2009
253
Engineered cobalt oxide nanoparticles readily enter cells
Papis, E. / Rossi, F. / Raspanti, M. / Dalle-Donne, I. / Colombo, G. / Milzani, A. / Bernardini, G. / Gornati, R. | 2009
I
Author Index
| 2009
iii
EUROTOX 2009 Organising Committees
| 2009
S1
Safety for people and environment
Foth, H. | 2009
S3
Regulatory approach to first-in-human trials with monoclonal antibodies
Reichmann, G. | 2009
S4
Alkyl sulphates, alkane sulphonates and alpha-olefin sulphonates
Fruijtier-Polloth, C. | 2009
S5
Ten proposals to improve testing and risk assessment
Ruden, C. | 2009
S7
Introduction to safety pharmacology
Valentin, J. P. | 2009
S8
Emerging trends and approaches in safety pharmacology
Valentin, J. P. | 2009
S10
Applying the TTC concept to skin sensitisation and inhalation toxicity
Safford, B. / Carthew, P. | 2009
S11
Primer on human exposure assessment for chemical risk assessment
McKone, T. | 2009
S12
Quantitative uncertainty analysis: Model case study
McKone, T. | 2009
S18
Rho-inhibiting toxins
Just, I. / Dreger, S. C. / Genth, H. | 2009
S19
The botulinum neurotoxins between toxicology and pharmacology
Montecucco, C. | 2009
S20
Interplay of DNA repair and damage signaling in genotoxin-induced apoptosis and necrosis
Kaina, B. | 2009
S21
Interplay of EGF receptor and DNA damage pathways
Peter Rodemann, H. / Dittmann, K. / Toulany, M. / Minjgee, M. | 2009
S24
Special aspects: Species differences, different life stages, exposure routes
Clewell, H. | 2009
S25
Use of dendritic cells for the identification and characterization of chemical allergens
Pallardy, M. | 2009
S28
Competing roles of reductases in the detoxification of carcinogens
Maser, E. | 2009
S30
Genomics and its surrounding technologies. Looking to the future of toxicogenomics
Schmitt, C. S. / Hewitt, P. G. | 2009
S31
Metabolite profiling-A new tool for the identification of toxicological effects of chemicals
Kamp, H. / Buesen, R. / Cunha, G. C. / Fabian, E. / Fischer, W. / Herold, M. / Leibold, E. / Looser, R. / Krennrich, G. / Mellert, W. | 2009
S33
The CHMP guideline on environmental risk assessment of medicinal products for human use: Three years of regulatory experience
Kuster, A. / Hickmann, S. / Rechenberg, B. | 2009
S35
An in vitro model of the human epithelial airway barrier to study the toxicity of nanoparticles
Rothen-Rutishauser, B. / Clift, M. / Brandenberger, C. / Lehmann, A. / Muller, L. / Raemy, D. / Gehr, P. | 2009
S37
Sens-it-iv: Novel testing strategies for in vitro assessment of allergens
Roggen, E. L. | 2009
S38
The use of humanised mice in the risk assessment of non-genotoxic carcinogens
Elcombe, C. | 2009
S39
Ethyl methanesulfonate (EMS): In vivo genotoxicity, cross species pharmacokinetic evaluation, and extrapolation to man
Gocke, E. / Lave, T. | 2009
S43
Effects of fine atmospheric particles on human respiratory epithelium: The role of organic compounds in oxidative stress, inflammatory and repair responses
Marano, F. | 2009
S44
Inflammatory processes in a mouse model of chronic pulmonary diseases by cigarette smoke inhalation
Haussmann, H. J. / Van Miert, E. / Stinn, W. | 2009
S46
The role of clinical toxicology units in public hospitals:An important source of data for toxicosurveillance
Ferrer-Dufol, A. / Xarau, S. N. / Guillen, S. M. / Arieta, R. M. / Ballesteros, S. / Ramon, F. | 2009
S48
Zebrafish embryos as a model in general toxicology
Braunbeck, T. | 2009
S49
Analysis of signaling pathways by knock down screens in zebrafish
Hertog, J. d. | 2009
S50
Deviation from additivity in mixture toxicity: Nonlinear dose-response and relevance for genotoxicity
Lutz, W. K. | 2009
S51
Physicochemical behaviors of photosensitizing drugs
Bosca, F. | 2009
S52
Clinical photosensitisation: Phototoxicity testing in man
Ferguson, J. | 2009
S53
Relevance of WEC as additional test to animal based testing
Menegola, E. | 2009
S55
Investigating partial agonism of the aryl hydrocarbon receptor
Bell, D. / Bazzi, R. | 2009
S62
An examination of the toxicity of small heterocycles towards the ciliates Tetrahymena pyriformis
Schramm, F. / Paschke, A. / Schuurmann, G. | 2009
S63
The COLIPA strategy for animal-free genotoxicity testing
Diembeck, W. / Carmichael, P. / Aardema, M. / Fautz, R. / Harvey, J. / Hewitt, N. / Latil, A. / Marrec-Fairley, M. / Pfuhler, S. / Quedraogo, G. | 2009
S64
The cytotoxic activity of various medicinal plants on the cancer cells
Amirghofran, Z. / Zand, F. / Javidnia, K. / Miri, R. | 2009
S66
Dynamic culture in multicompartment bioreactor upregulates cytochrome expression in human hepatocytes
Ahluwalia, A. / Vinci, B. / Cedric, D. / Wilkinson, M. / Maurel, P. | 2009
S71
Evaluation of DNA damage on human pulmonary cells exposed to organic extract of PM10 collected in urban and rural areas
Cavallo, D. / Ursini, C. L. / Fioretti, M. / Cabella, R. / Ciervo, A. / Maiello, R. / Iavicoli, S. | 2009
S73
N-Acetyltransferase 1 (NAT1) and cytochrome P450 1 (CYP1) activities in subtypes of HaCaT cells
Bonifas, J. / Hennen, J. / Scheitza, S. / Blomeke, B. | 2009
S74
In vitro assessments of hepatic toxicity using the xCELLigence real-time cell analyzer
Schmitz, M. / Boess, F. / Watzele, M. / Suter-Dick, L. / Roth, A. B. | 2009
S75
The response of isolated gastrointestinal strips to reference substances' during long-term incubation
Chlopecka, M. / Dziekan, N. / Mendel, M. / Wiechetek, M. | 2009
S76
Effect of rhamnocytrine-4prime-beta-d-galactopyranoside, isolated from Astragalus hamosus L., in combination with cyclophosphamide on cell viability in freshly isolated rat hepatocytes
Kondeva-Burdina, M. / Mitcheva, M. / Krasteva, I. / Nikolov, S. | 2009
S77
The effect of sulfur mustard on histone proteins in active and inactive chromatin
Jafari, M. / Rabbani, A. / Nateghi, M. / Salehi, M. | 2009
S78
An in vitro assay for assessing methylmercury and PCB153 effects on blood-brain barrier (BBB) integrity
Roda, E. / Sinatra, M. G. / Coccini, T. / Manzo, L. | 2009
S79
PM10 in Milan: Seasonal variations in eliciting biological effects on A549 cell line
Camatini, M. / Mantecca, P. / Corvaja, V. / Gualtieri, M. | 2009
S85
Newly developed oximes K117 and K127-Reactivation of human brain cholinesterases inhibited by tabun
Marek, J. / Kuca, K. / Cabal, J. / Musilek, K. / Karasova, J. / Jung, Y. S. / Jun, D. / Pohanka, M. | 2009
S86
Mycophenolic acid impairs growth and differentiation of rat embryos in vitro at subtherapeutic concentrations
Eckardt, K. / Muller, N. / Stahlmann, R. | 2009
S87
Optimization of culture and measurement conditions for improved stability and sensitivity of cell physiology monitoring systems for toxicology applications
Ehret, R. / Stutz, E. / Kubisch, R. / Drechsler, S. / Fleischer, M. | 2009
S89
Genetic background for mercury metabolism
Gundacker, C. / Wittmann, K. J. / Kukuckova, M. / Komarnicki, G. / Hikkel, I. / Gencik, M. | 2009
S90
A novel in vitro system for the toxicological evaluation of genotoxic compounds
Boehme, K. / Dietz, Y. / Hewitt, P. G. / Mueller, S. O. | 2009
S92
Thioacetamide-induced fulminant hepatic failure and encephalopathy in rats: A metabonomic approach in liver and serum
Zira, A. / Kostidis, S. / Zarros, A. / Mikros, E. / Theocharis, S. | 2009
S93
Gene expression profiling in the lung from cynomolgus monkeys repeatedly exposed to welding fume
Heo, J. D. / Oh, J. H. / Lee, K. / Song, C. W. / Yoon, S. / Han, J. S. | 2009
S94
Acrylamide exposure and dose-effect relations on the genome-wide gene expression profile of human target cells
Lampen, A. / Hummel, M. / Zeilinger, K. / Luebberstedt, M. / Ehlers, A. | 2009
S95
Long term metabolic changes induced in idiosyncrasy-like liver toxicity
Colet, J. M. / Conotte, R. | 2009
S96
The crosstalk between Ah receptor and canonical Wnt signaling extends beyond a simple regulation of AhR expression
Prochazkova, J. / Bryja, V. / Richterova, M. / Bernatik, O. / Kozubik, A. / Machala, M. / Vondracek, J. | 2009
S100
A polymorphism in the Ah-receptor gene is related to hypertension and endothelium-dependent vasodilation
Lind, P. M. / Ingelsson, E. / Syvanen, A. C. / Lind, L. | 2009
S101
Cytotoxicity of microcystins and nodularin
Ufelmann, H. / Kruger, T. / Luckas, B. / Schrenk, D. | 2009
S104
Genetically engineered Clostridium botulinum C2 toxin as a molecular trojan horse to deliver biomolecules into mammalian cells
Fahrer, J. / Plunien, R. / Binder, U. / Barth, H. | 2009
S108
The activity of fructose diphosphatase and acid-base status in rats exposed to fluoride and ammonium chloride
Khalili, J. / Biloklytska, H. | 2009
S109
In the rat, gamma-hydroxybutyrate is detoxified not only by hepatocytes but also by renal proximal tubules: A carbon 13 NMR study
El Hage, M. / Baverel, G. / Martin, G. | 2009
S110
Hyponatremic effect caused by 3,4-methylenedioxymethamphetamine (ecstasy) in rats: The role of metabolic bioactivation
Carmo, H. / Gomes, D. / Carvalho, F. / Remiao, F. / Branco, P. / Ferreira, L. / Guedes de Pinho, P. / de Lourdes Bastos, M. | 2009
S111
Ellagic acid reduced nicotine induced withdrawal syndrome in mice
Perez-Pasten, R. / Atitlan-Gil, A. / Zuniga-Perez, C. / Filardo-Kestrupp, S. / Otazo-Sanchez, M. E. / Madrigal-Santillan, O. / Chamorro-Cavallos, G. | 2009
S112
Impact of chronic exposure with low dose of depleted uranium on rats treated with different acetaminophen doses
Grandcolas, L. / Rouas, C. / Grison, S. / Baudelin, C. / Souidi, M. / Gourmelon, P. / Gueguen, Y. | 2009
S113
Propofol and metabolites monitoring in serum of patients with induced sedation
Cale, R. / Aragao, I. / Martins, H. / Cardoso, G. / Ferreira, L. M. / Branco, P. S. / Bastos, M. L. / Guedes de Pinho, P. | 2009
S114
Interaction of ABC transporters with environmental toxicants
Oosterhuis, B. / Krisztina, V. / Erika, V. / Hristos, G. / Istvan, J. / Peter, K. | 2009
S117
Effect of long term feeding of T-2 toxin contaminated diet in young common carp (Cyprinus carpio L.)
Balogh, K. / Szabo-Fodor, J. / Heincinger, M. / Mezes, M. | 2009
S118
Differences in metabolism and GSH conjugation of 2-methyl-1,4-naphthoquinone in vivo and in vitro suggest oversensitivity for oxidative stress-induced toxicity in vitro
Lutz, U. / Pointon, A. V. / Parry, J. D. / Klotz, L. O. / Gant, T. W. / Lutz, W. K. | 2009
S119
Concentration of malondialdehyde in plasma of lead-workers
Flajs, D. / Pizent, A. / Domijan, A. M. / Peraica, M. | 2009
S120
Effects of BDE-99 exposure in liver antioxidant status
Linares, V. / Alonso, V. / Belles, M. / Albina, M. L. / Sirvent, J. / Domingo, J. L. / Sanchez, D. | 2009
S121
Lysine acetylsalicylate elicits full survival of Wistar rats exposed to a lethal dose of paraquat
Dinis-Oliveira, R. / Pontes, H. / Remiao, F. / de Lourdes Bastos, M. / Duarte, J. A. / Carvalho, F. | 2009
S122
Effect of multiple treatment with alcohol on some liver antioxidant biochemical parameters in spontaneously hypertensive rats (SHRs) versus normotensive rats (NTR)
Simeonova, R. / Vitcheva, V. / Mitcheva, M. | 2009
S123
Involvement of reactive oxygen and nitrogen species on doxorubicin-induced toxicity to rat cortical neurons
Lopes, M. A. / Meisel, A. / Carvalho, F. / de Lourdes Bastos, M. | 2009
S124
HuR and p38-MAP kinase control ultraviolet B-induced posttranscriptional regulation of cyclooxygenase-2 expression in HaCaT human keratinocytes
Fernau, N. S. / Fugmann, D. / Grether-Beck, S. / Krutmann, J. / Klotz, L. O. | 2009
S125
Assessment of diazinone induced oxidative stress and pyridoxine protective effects on neuroglial U373MG cell line
Saberi, M. / Baghlani, K. Z. / Bahrami, F. | 2009
S129
c-Fos/AP-1 dependent regulation of the three prime exonuclease 1 (TREX1) by genotoxic stress
Christmann, M. / Tomicic, M. / Aasland, D. / Schulz, J. / Berdelle, N. / Reischmann, P. / Birkner, R. / Rasenberger, B. / Kaina, B. | 2009
S130
DNA strand breaks detected by Comet assay in sputum leucocytes of workers exposed to fumes of bitumen: A pilot study
Marczynski, B. / Raulf-Heimsoth, M. / Kendzia, B. / Spickenheuer, A. / Vosshans, B. / Borowitzki, G. / Lee, E. H. / Kafferlein, H. U. / Pesch, B. / Bruning, T. | 2009
S131
Association of manganese superoxide dismutase (MnSOD) gene polymorphism and prostate cancer risk
Eken, A. / Erdem, O. / Arsova-Sarafinovska, Z. / Matevska, N. / Savaser, A. / Sayal, A. / Dimovski, A. / Ozgok, Y. / Aydin, A. | 2009
S132
Assessment of solar radiation-induced DNA damage and apoptosis in pig ear skin organ culture and reconstructed human epidermis
Bacqueville, D. / Mavon, A. / Duplan, H. | 2009
S133
Organochlorine pesticide triggers stimulation of c-Src dependent HER1-ERK 1/2 signaling pathway in mammary gland and N-methyl-N-nitrosourea (NMU)-induced mammary tumors in rats
Pena, D. / Pontillo, C. / Garcia, M. A. / Cocca, C. / Alvarez, L. / Lantos, V. L. / Frahm, I. / Bergoc, R. / de Pisarev, D. K. / Randi, A. | 2009
S134
The effects of curcumin as a chemoprotective agent against aflatoxin B1 induced toxicity in rats
Poapolathep, A. / Poapolathep, S. / Machii, K. / Nakayama, H. / Kumagai, S. | 2009
S136
Genotoxicity of atmospheric polycyclic aromatic hydrocarbons mixtures: From artificial to realistic mixtures
Tarantini, A. / Douki, T. / Lefebvre, E. / Marie, C. / Ravanat, J. L. / Maitre, A. | 2009
S137
Mutagenic toxicity of acrylamide and glycidamide in germ cells of mice
Wang, R. S. / McDaniel, L. / Manjanatha, M. / Shelton, S. / Mei, N. | 2009
S138
Role of S-adenosylmethionine as carcinogenic and/or co-carcinogenic factor in epigenetic silencing of tumour related genes in human lung
Hamed, H. / Torky, A. / Glahn, F. / Gherbal, R. / Foth, H. | 2009
S139
Human relevance of induction of tunica vaginalis mesotheliomas in rats by acrylamide and other xenobiotics
Friedman, M. / Maronpot, R. / Zeiger, E. / McConnell, E. / Kolenda-Roberts, H. / Wall, H. | 2009
S145
Histological study of the placenta of mice following phenol administration
Monfared, A. L. / Tootian, Z. / Fazelipour, S. | 2009
S149
Gene expression profiling in rat cerebellum and striatum following in utero and lactational exposure to non-dioxin-like polychlorinated biphenyls
De Boever, P. / Boix, J. / Hollanders, K. / Felipo, V. / Schoeters, G. | 2009
S151
Perfluorinated compounds (PFC) in human breast milk
Volkel, W. / Mosch, C. / Kiranoglu, M. / Verdugo-Raab, U. / Fromme, H. | 2009
S152
Evaluation of urinary kidney biomarkers in rat models of acute and subchronic nephrotoxicity
Hoffmann, D. / Henzler, T. / Herget, T. / Callanan, J. / Dekant, W. / Hewitt, P. / Mally, A. | 2009
S153
Genotoxic effects in Hospital Laboratory workers exposed to complex chemical mixtures
Cavallo, D. / Fresegna, A. M. / Ciervo, A. / Maiello, R. / Buresti, G. / Iavicoli, S. | 2009
S155
NMDA Receptor antagonist memantine suppresses DFP-induced oxidative/nitrosative stress and dendritic damage in rat brain
Gupta, R. / Zaja-Milatovic, S. / Milatovic, D. | 2009
S160
Polychlorinated dibenzo-p-dioxin (PCDD), polychlorinated dibenzofuran (PCDF) and PCB levels in human milk in Turkey
Cok, I. / Donmez, M. K. / Uner, M. / Demirkaya, E. / Henkelmann, B. / Shen, H. / Kotalik, J. / Schramm, K. W. | 2009
S164
Tamoxifen hepatotoxicity-Interaction with resveratrol and deferiprone in rats
Cerna, P. / Kotyzova, D. / Eybl, V. | 2009
S166
Anti-inflammatory, toxic effects, biochemical and pathological analysis in presence or lack of vitamins C and E, and cytotoxicity of n-hexane, methanolic and ethyl acetate extracts of Sambucus ebulus
Saravi, S. S. / Shokrzadeh, M. | 2009
S167
Evaluation of impaired neuronal cell development-availability of reelin immunolocalization analysis and monitoring of neuron distribution in the hippocampal dentate gyrus
Saegusa, Y. / Fujimoto, H. / Woo, G. H. / Kawai, M. / Matsumoto, S. / Hirose, M. / Nishikawa, A. / Mitsumori, K. / Shibutani, M. | 2009
S168
Impact of cafeic acid phenethyl ester (CAPE) on amiodarone-induced pulmonary fibrosis in rat
Hemmati, A. A. / Zaeemzadeh, N. / Arzi, A. / Jalali, M. T. / Rashidi, I. | 2009
S170
The role of metabolism in T-cell mediated drug hypersensitivity reactions
Naisbitt, D. | 2009
S172
Paraquat and temperature affect nonspecific immune response of neotropical freshwater fish Colossoma macropomum
Salazar-Lugo, R. / Estrella, A. / Oliveros, A. / Rojas-Villarroel, E. / Villalobos, L. / Lemus, M. | 2009
S173
Investigation of the sensitising potential of textile dyes using a biphasic protocol of the local lymph node assay
Ahuja, V. / Sonnenburg, A. / Baumann-Wilschke, I. / Platzek, T. / Stahlmann, R. | 2009
S174
Risk of repeated inhalation exposure to the contact allergen dinitrochlorobenzene (DNCB) in rats
van Triel, J. J. / Arts, J. H. / Kuper, C. F. | 2009
S175
Precision cut lung slices (PCLS) as a tool to predict effective LPS concentrations for in vivo use in common marmoset monkeys
Seehase, S. / Switalla, S. / Schlumbohm, C. / Knochelmann, N. / Krug, N. / Sewald, K. / Kaup, F. J. / Fuchs, E. / Braun, A. | 2009
S176
Urban aerosol directly stimulates antigen presentation cells in vitro and cause airway inflammation in vivo
Yoshida, T. / Yoshioka, Y. / Kayamuro, H. / Yamashita, K. / Higashisaka, K. / Nakanishi, R. / Abe, Y. / Kawai, Y. i. / Mayumi, T. / Yoshikawa, T. | 2009
S177
Skin sensitization to p-phenylenediamine: The role of exposure time and dose for the elicitation response in allergic patients
Goebel, C. / Coenraads, P. J. / Kock, M. / Bloemeke, B. | 2009
S178
Nanotechnology-Opportunities and risks from the statutory accident insurance point of view
Beth-Hubner, M. | 2009
S179
In vitro nanotoxicologic studies of silica-nanoparticles using dermal cell lines
Yoshikawa, T. / Nabeshi, H. / Matsuyama, K. / Nakazato, Y. / Imazawa, T. / Yoshioka, Y. / Abe, Y. / Kawai, Y. i. / Mayumi, T. / Itoh, N. | 2009
S180
The toxic effect of monodisperse amorphous silica particles studied on an in vitro model of the human air-blood barrier
Kasper, J. / Hermanns, I. / Maskos, M. / Bantz, C. / Kirkpatrick, J. | 2009
S181
Evaluation of size-dependent acute toxicity and toxicokinetics of amorphous nanosilicas
Nabeshi, H. / Yoshikawa, T. / Matsuyama, K. / Nakazato, Y. / Imazawa, T. / Yoshioka, Y. / Abe, Y. / Kawai, Y. i. / Mayumi, T. / Ito, N. | 2009
S183
The degree of functionalization affects in vitro cytotoxicity of multi-walled carbon nanotubes (CNTs)
Coccini, T. / Roda, E. / Sarigiannis, D. A. / Mustarelli, P. / Profumo, A. / Manzo, L. | 2009
S191
Models for extrapolation of long-term effects of pharmaceuticals in the environment using therapeutic information
Altenburger, R. / Gundel, U. / Ali-Aycheh, M. / Hanisch, K. / Kuster, A. / Rechenberg, B. / Schreiber, R. | 2009
S193
Assessment of polychlorinated biphenyls: Prospects for a global approach
Rotondo, F. / Colacci, A. / Silingardi, P. / Mascolo, M. / Morandi, E. / Perdichizzi, S. / Grilli, S. / Serra, R. / Vaccari, M. | 2009
S194
Histopathological changes in the gills of freshwater fish, Oreochromis niloticus (L.) Juveniles exposed to Moringa oleifera (Lam.) fresh root-bark extract
Adesina, B. T. / Oguntuga, A. O. | 2009
S195
Comparison of the sensitivity of embryonic and juvenile developmental stages of Danio rerio to chemical substances
Macova, S. / Dolezelova, P. / Plhalova, L. / Pistekova, V. / Svobodova, Z. / Bedanova, I. / Voslarova, E. | 2009
S196
Role of PAHs metabolizing enzymes polymorphisms in urinary 1-OHP levels in children
Sanchez-Guerra, M. / Pelallo-Martinez, N. A. / Martinez, F. D. / Oropeza-Hernandez, L. F. / Guaderrama-Diaz, M. / Lara-Montoya, S. / Martinez-Aguilar, G. / Quintanilla-Vega, B. | 2009
S197
The role of AhR in doxin-induced modulation of bone microarchitecture and mechanical strength
Herlin, M. / Aula, A. / Miettinen, H. M. / Korkalainen, M. / Finnila, M. / Tuukkanen, J. / Hakansson, H. / Viluksela, M. | 2009
S198
Identification and toxicological evaluation of musk fragrances and thiophenes in extracts of river sediment samples
Vykopalova, L. / Pencikova, K. / Ciganek, M. / Neca, J. / Vondracek, J. / Brack, W. / Varel, U. L. / Streck, G. / Machala, M. | 2009
S209
Retrospective evaluation of Acute Reference Doses (ARfD) for pesticides in the European Union
Moeller, T. / Stein, B. / Solecki, R. | 2009
S210
Neurotoxicological effects induced by the insecticide fipronil
Anadon, A. / Martinez, M. A. / Pita, R. / Martinez, M. / Castellano, V. / Caballero, V. / Ares, I. / Ramos, E. / Martinez-Larranaga, M. R. | 2009
S211
Effects of herbicide pendimethalin on uterotrophic response and gene expression in rat uterus
Undeger, U. / Schlumpf, M. / Lichtensteiger, W. | 2009
S212
Acetycholinesterase and butyrilcholinesterase in donkey and their inhibition by organophosphates
Kuzner, J. / Bajuk, B. P. | 2009
S213
Effect of 10 oxime cholinesterase reactivators on cyclosarin-intoxicated rats
Karasova, J. Z. / Kassa, J. / Musilek, K. / Pohanka, M. / Kuca, K. | 2009
S214
Associations between PON1 and CYP1A1 genetic polymorphisms and clinical findings of a Greek population exposed to pesticides
Alegakis, A. / Zafiropoulos, A. / Tzanakakis, G. / Liesivuori, J. / Koutis, C. / Tsatsakis, A. | 2009
S217
Investigation of the role of glutathione S-transferase isozymes in pyrethroid resistance of Helicoverpa armigera in Turkey
Konus, M. / Ugurlu, S. / Iscan, M. | 2009
S218
The effects of organophosphate exposure on serotonergic systems
Ramadan, S. / Morris, C. / Harris, J. | 2009
S219
Impact of lead toxicity on male rat reproduction at "Hormonal and Histopathological Levels"
El-Sayed, Y. S. / El-Neweshy, M. S. | 2009
S220
Effects of occupational exposure to lead: Flow cytometric study
Laffon, B. / Garcia-Leston, J. / Roma-Torres, J. / Teixeira, J. P. / Costa, C. / Coelho, P. / Monteiro, S. / Mayan, O. / Valdiglesias, V. / Pasaro, E. | 2009
S221
Effect of cadmium on 24-h pattern in expression of clock genes in rat medial basal hypothalamus
Rios-Lugo, M. J. / Barquilla, M. d. / Jimenez-Ortega, V. / Cardinali, D. / Parras, A. I. | 2009
S222
Effect of crude Chromolaena odorata leaf extract alone and in combination with sodium arsenite in mice
Akinwumi, K. / Odunola, O. / Osifeso, O. | 2009
S223
Zinc protects from cadmium-induced oxidative stress in the bone tissue of rats
Brzoska, M. / Rogalska, J. / Kupraszewicz, E. / Roszczenko, A. | 2009
S224
Effects of heavy metals and tobacco smoke condensate on the glutathione-level in cultured human lung cells
Thomas, S. / Glahn, F. / Foth, H. | 2009
S225
Effect of magnesium supplementation on blood cadmium, zinc and copper levels in rabbits exposed to prolonged cadmium intoxication
Bulat, Z. P. / Dukic-Cosic, D. / Bulat, P. / Matovic, V. | 2009
S226
Memory and cholinergic system impaired by sub-chronic exposure to uranium in young rats
Helene, B. / Resve, G. / Vacher, C. M. / Dublineau, I. / Philippe, V. / Gourmelon, P. / Taouis, M. / Lestaevel, P. | 2009
S227
Natural co-occurrence of aflatoxins and cyclopiazonic acid from corn grown in Egypt
Amra, H. | 2009
S229
Effects of purity-controlled PCB52 and PCB180 on dopamine-dependent behavior in rat offspring after maternal exposure
Lilienthal, H. / Heikkinen, P. / Danielsson, C. / Andersson, P. / Viluksela, M. | 2009
S230
EFSAs risk assessment of uranium in foodstuffs and water
Castoldi, A. F. / Ferrari, P. / Bordajandi, L. R. / Curtui, V. / Arcella, D. / Fabiansson, S. / Heppner, C. | 2009
S231
In vitro toxicity of furan and its metabolite(s) in liver cells
Brueck, J. / Schneider, T. / Schrenk, D. | 2009
S232
European risk assessments of undesirable substances in feed: Animal and human health perspectives
Dorne, J. L. / Bertelsen, U. / Heppner, C. / Alexander, J. / Cravedi, J. P. / Cockburn, A. / Fink-Gremmels, J. | 2009
S235
Safety evaluation of a refined arachidonic acid-rich oil
Casterton, P. L. / Curry, L. L. / Lina, B. A. / Wolterbeek, A. P. / Kruger, C. L. / Hayes, A. W. | 2009
S236
Prioritization of textile dyes from a consumer health perspective
Bruschweiler, B. / Gnehm, R. / Burgi, D. / Zarn, J. | 2009
S237
Relative photomutagenic potency of furocoumarins and limettin
Raquet, N. / Lohr, C. / Schrenk, D. | 2009
S241
How valid are "old" repeated dose toxicity studies for chemical risk assessment?
Batke, M. / Escher, S. / Bitsch, A. / Melber, C. / Simetska, N. / Mangelsdorf, I. | 2009
S245
Classification of NDL-PCB congeners based on extensive in vitro screening and multivariate statistics
Andersson, P. / Al-Anati, L. / Stenius, U. / Fernandes, E. A. / van Duursen, M. / Westerink, R. / Fonnum, F. / Wigestrand, M. / Stenberg, M. / Hamers, T. | 2009
S247
Evaluation of risk assessment factors for inter-species and time-extrapolation
Escher, S. / Mangelsdorf, I. | 2009
S248
Genotoxicity studies with the colorant Acid Red 1
Fieblinger, D. / Platzek, T. | 2009
S250
Quetiapine treatment in resistant depression: A prospective study
Hafnia, E. / Ionescu, D. | 2009
S251
Pharmacobezoars: Literature review; hypothesis of formation and therapeutics repercussions
Albertini, L. / Tossa, P. / Rigaux-Barry, F. / Boltz, P. / Manel, J. | 2009
S252
Functional status of synaptic structures in posthypoxic period
Lutov, V. / Sarmanaev, S. / Gizatullin, A. / Tuktarova, R. | 2009
S254
A case of criminal poisoning by combination of carbamazepine and midazolam
Milosavljevic, B. / Vujovic, M. / Simic, A. / Seskar-Stojancov, S. | 2009
S255
Effect of diltiazem on retention and retrieval of memory in young and aged mice
Honarmand, M. M. / Arzi, A. / Jamshidi, S. / Latifi, M. | 2009
S261
Improved analytical method for monitoring exposure to volatile compounds for occupational risk prevention
Martinez, C. E. / Sanchez, M. A. / Gisbert, E. V. | 2009
S262
The impact of drug monitoring in a case of drug resistant neonate arrhythmia
Toutoudaki, M. / Germanakis, I. / Briassoulis, G. / Tzatzarakis, M. / Christakis-Hampsas, M. / Tsatsakis, A. | 2009
S263
Ambulatory intravenous infusion for use in preclinical studies in the dog
Pickersgill, N. / Gerhardy, C. / Briffaux, J. P. / Chopinaud, M. | 2009
S264
Development and validation of a GC/MS method for the determination of buprenorphine and norbuprenorphine in blood
Papoutsis, I. / Nikolaou, P. / Athanaselis, S. / Pistos, C. / Spiliopoulou, C. / Maravelias, C. | 2009
S265
Hepatoprotective and antioxidant activity of phytic acid and/or catechin against carbon tetrachloride-induced hepatotoxicity in rats
Hassan, S. / Rizk, M. Z. / El-Sharkawi, F. / Badary, O. / Kadry, M. O. | 2009
S266
European Modular Education and Training Programme in Safety Sciences for Medicines (SafeSciMET)
Dietrich, D. R. / Vermeulen, N. P. / Price, S. / Guentert, T. W. | 2009
S267
Regulatory approach of the dietary risk assessment of biocidal products
d'Yvoire, M. B. / van de Plassche, E. | 2009
S268
Chlorpyrifos and neurodevelopmental toxicity: Critical assessment and expert elicitation
Magnanti, B. / Carreira, S. C. / Saunders, M. / Bartonova, A. / Von Krauss, M. | 2009
S269
Validation of the auditory startle reflex in rats
Betat, A. M. / Bentz, S. / Forster, R. / Frary, S. / Basset, L. / Legois, J. / Chevalier, G. | 2009
S270
OEL vs. DNEL or expert judgement vs. default factors-Reference values under REACh exemplified by styrene
Schafer, C. / Dorn, S. B. / Jakupoglu, C. / Mostert, V. | 2009
S271
Alternatives to animal testing under the EU cosmetics directive
Heuer, N. / Vogel, R. | 2009
S272
Regulatory requirements for in vitro systems to meet performance standards during validation and over time
Klausner, M. / Kubilus, J. / Ayehunie, S. / Kaluzhny, Y. / Kandarova, H. / Kearney, P. / Hayden, P. / Sheasgreen, J. | 2009
v
EUROTOX 2009 Sponsors
| 2009
x
Contents
| 2009
The rapid analysis of opiates from low volume whole blood samples by LC-MS/MS utilizing TurboFlow methods
Scurati, S. / Robinson, S. / McDonnel, S. / Duretz, B. / Ashton, P. | 2009
The COLIPA strategy for developing and evaluating animal alternatives for skin sensitization testing
Aeby, P. / Ashikaga, T. / Bessou-Touya, S. / Diembeck, W. / Gerberick, F. / Kern, P. / Marrec-Fairley, M. / Maxwell, G. / Ovigne, J. M. / Sakaguchi, H. | 2009
Serum albumin, and not lipoprotein paraoxonase, is responsible for paraoxon detoxication at in vivo toxicological relevant conditions
Sogorb, M. A. / Carrera, V. / Vilanova, E. | 2009
Sex-differences in the pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolite 3,4-methylenedioxyamphetamine (MDA) in Sprague-Dawley rats
Fonsart, J. / Menet, M. C. / Debray, M. / Noble, F. / Scherrmann, J. M. / Decleves, X. | 2009
SERS technique and its applications for toxicological evaluations in experimental breast cancer
Ciurlea, S. A. / Dehelean, C. / Ionescu, D. / Muresan, A. / Cinta-Pinzaru, S. / Loghin, F. | 2009
Asbestos exposure affects poly(ADP-Ribose) polymerase-1 activity: Role in the asbestos-induced carcinogenesis
Tomasetti, M. / Strafella, E. / Amati, M. / Nocchi, L. / Saccucci, F. / Santarelli, L. | 2009
Thymus histological study in Zn supplemented mice
Saldivar, L. | 2009
Evaluation of in vitro genotoxicity of magnetite nanoparticles
Gomaa, I. | 2009
Herbicide distribution in soils of a riparian forest and neighboring sugar cane field
Bicalho, S. / Langenbach, T. / Hagler, A. | 2009
The noxological value of the environment in high schools
Savicheva, N. | 2009
Effective extraction and detection of some organophosphorus insecticides seized in Egypt
Elwan, F. | 2009
Aflatoxin M1 contamination in UHT milk in Tabriz (northwest of Iran)
Ghazani, M. H. | 2009
Safety and efficacy of a novel chromium (III) dinicocysteinate (CDNC) in type II Zucker Diabetic Fatty (ZDF) rats
Bagchi, D. / Jain, S. / Rains, J. / Croad, J. / Bagchi, M. | 2009
The efficacy and tolerability of memantine in the therapy of schizophrenia
Ionescu, D. / Dehelean, C. / Dragan, S. | 2009
Evaluation of inflammatory, cytotoxic, genotoxic BAL parameters and histological findings after exposure to amosite, refractory ceramic fibres and cigarette smoke
Hurbankova, M. / Cerna, S. / Beno, M. / Barancokova, M. / Valachovicova, M. / Wimmerova, S. / Kovacikova, Z. / Tatrai, E. | 2009
Global DNA promoter methylation in cancer
Plass, C. | 2009
Scientific and regulatory approaches for the preclinical safety evaluation of biologics
Bernardi, C. | 2009
Oxidative and nitrosative stress-induced neurotoxicity in primary cultured rat cerebellar granule neurons
Smith, R. A. / Fatokun, A. A. / Smith, A. J. / Stone, T. W. | 2009
Experiences with the Swedish environmental classification system of pharmaceuticals on www.fass.se
Holm, G. | 2009
Genotoxicity and carcinogenicity of acrylamide
Klaunig, J. / Rice, J. | 2009
Barcode-like toxicogenomic profiles identify several hundred genes that respond to environmental toxicants in the zebrafish embryo
Strahle, U. / Yang, L. / Ho, N. Y. | 2009
Comparison of progestin transcriptional profiles in rat mammary gland using laser capture microdissection and whole tissue sampling
Torno, N. / Frisk, A. L. / Beekman, J. M. / Hartwig, A. / Meyer, K. | 2009
Binary mixtures of pharmaceuticals and nickel
Rudzok, S. / Bauer, M. | 2009
In vitro sensitivity of granulo-monocytic progenitors as a new endpoint in the ACuteTox project
Cerrato, L. / Valeri, A. / Bueren, J. / Albella, B. | 2009
In vitro toxicity and molecular epidemiology of indoor Aspergillus versicolor
Majorosova, M. / Pieckova, E. / Pangallo, D. | 2009
Renal effects of BDE-99 exposure and its relation to oxidative stress
Alonso, V. / Linares, V. / Belles, M. / Albina, M. L. / Sirvent, J. / Domingo, J. L. / Sanchez, D. | 2009
Changes in endothelial cell kinetics after short-term rat gavage exposure to riddelliine-An hepatic endothelial carcinogen
Nyska, A. | 2009
Evaluating the developmental neurotoxicity (DNT) potential of chemicals in an in vitro model based on human neurospheres
Rockel, T. / Abel, J. / Fritsche, E. | 2009
Estradiol valerate-induced atypical endometrial hyperplasia in experimental polycystic ovary
Saadi, H. A. / Rezvanfar, M. A. / Abdollahi, M. | 2009
High adaptation abilities of Anopheles gambiae to contrasting environmental conditions, a serious threat to malaria control efforts
Flora, M. F. / Samuel, W. / Frederic, T. / Felix, B. B. / Thomas, N. | 2009
In silico assessment of acute toxicity in rodents
Lagunin, A. / Zakharov, A. / Filimonov, D. / Poroikov, V. | 2009
Comparison of immune function tests using T-cell dependent antigens: A meta-analysis
Herzyk, D. | 2009
Predictive in vitro models of in vivo cataract formation by an H3-receptor antagonist
Momburg, R. / Maisonneuve, C. / Bertheux, H. / Bazot, D. / de Sousa, E. / Delongeas, J. L. / Claude, N. / Wormstone, M. / Sanderson, J. / Radreau, P. | 2009
ECG data acquisition by external telemetry for toxicology (ET2) in freely moving dogs: Validation by comparison with invasive telemetry
Milano, S. / Briffaux, J. P. / Chalencon, E. / Bory, C. / Baudet, S. / Lege, P. | 2009
Cyto-genotoxic effect of styrene and acrylonitrile combination
Strafella, E. / Tomasetti, M. / Bracci, M. / Amati, M. / Santarelli, L. | 2009
THP-1 monocytes but not macrophages as a potential alternative for CD34+ dendritic cells to identify chemical skin sensitizers
Lambrechts, N. / Verstraelen, S. / Hooyberghs, J. / Witters, H. / Van Tendeloo, V. / Van Cauwenberge, P. / Nelissen, I. / Van Den Heuvel, R. / Schoeters, G. | 2009
Multi-lab validation of an improved flow cytometric in vitro micronucleus assay using attached cell lines
Young, R. / Shi, J. / Bryce, S. / Nicolette, J. / Diehl, M. / Sonder, P. / Phonethepswath, S. / Avlasevich, S. / Raja, S. / Bemis, J. | 2009
Metabolomics: A novel tool for understanding the early-stage mechanistic underpinnings of drug action and safety
Milburn, M. / Mohney, R. / Boudonck, K. | 2009
Effects of Tunisian medicinal plant extracts on the expression of cell defense genes in human leukemia cell line K562 using cDNA arrays: Correlation with related biological activities
Bouhlel, I. / Skandrani, I. / Bhouri, W. / Kilani, S. / Ammar, R. B. / Valenti, K. / Mariotte, A. M. / Ghedira, K. / Laporte, F. / Franca, M. G. | 2009
Protective effects of myrrh (Commiphora molmol) emulsion against lead acetate-induced hepato- and immunotoxicity in rabbits
Ashry, K. / El-Sayed, Y. / Khamis, R. / El-Ashmawy, I. | 2009
Malondialdehyde (MDA) quantification in plasma of foundry workers: The oxidative stress perspective
Peixe, T. / Nascimento, E. / Loureiro, A. P. | 2009
The effect of wormwood (Artemisia absinthium L.) extract on brain region antioxidant system after intoxication by lead
Kharoubi, O. / Slimani, M. / Aoues, A. | 2009
Impact of gender and age on ochratoxin a toxicokinetics in rat
Vettorazzi, A. / Gonzalez-Penas, E. / Troconizc, I. F. / Arbillaga, L. / Corcuera, L. A. / Gil, A. G. / Lopez de Cerain, A. | 2009
Development and assessment of nanoparticle suspensions as fundament for toxicological analysis
Meiner, T. / Potthoff, A. / Richter, V. | 2009
Oxidative DNA damage by nanoparticles in human intestinal Caco-2 cells in the presence or absence of neutrophils
Gerloff, K. / Boots, A. W. / Winter, M. / Forster, I. / Albrecht, C. / Schins, R. P. | 2009
Impact of engineered nanoparticles on immune-related genes and processes in human alveolar epithelial cells
Nelissen, I. / Verstraelen, S. / De Boever, P. / Casals, E. / Ooms, D. / Leppens, H. / Hollanders, K. / Van Den Heuvel, R. / Schoeters, G. / Puntes, V. | 2009
Drinking water contamination by polychlorinated butadienes
Bruschweiler, B. / Marki, W. / Wulser, R. | 2009
ATHON NDL-PCB effect database-A tool to facilitate the cumulative risk assessment of NDL-PCBs
Westerholm, E. / Boix, J. / Miettinen, H. M. / Roos, R. / Antunes-Fernandes, E. / Westerink, R. / van Duursen, M. / Stenberg, M. / Carreira, S. C. / Machala, M. | 2009
Selecting a Toxicity Reference Value (TRV) for Lindane to assess health risks associated with a school contamination in France
Rousselle, C. / Bonvallot, N. / Kairo, C. / Clinard, F. / Lirussi, F. / Belzunge, L. P. / Menetrier, F. | 2009
REACH is but the first step-on the need to improve testing and risk assessment for industrial chemicals
Ruden, C. | 2009
Atmospheric VOC composition in downtown Rome in the last fifteen years
Fanizza, C. / Brocco, D. / Manigrasso, M. / Avino, P. | 2009
Identification of genes involved in phenobarbital-induced tumorigenesis: Emphasis on altered DNA methylation and expression
Goodman, J. | 2009
Molecular aspects of adverse drug reactions - from molecule to man
Park, K. | 2009
Mechanisms of carcinogenesis: Regulatory perspective
Degen, G. H. / Bolt, H. M. | 2009
Development of an in vitro assay for the assessment of photosensitizers
Schepky, A. / Tepe, Y. / Karschuk, N. / Spieker, J. / Gerlach, S. / Wenck, H. / Schmucker, R. / Wittern, K. P. / Reuter, H. | 2009
GC-MS method for methadone quantification in plasma
Ciobanu, A. M. / Baconi, D. L. / Barca, M. / Negrei, C. / Cristescu, I. / Balalau, D. | 2009
MucilAir: A novel human 3D airway epithelium model for long term toxicity testing
Huang, S. / Derouette, J. P. / Constant, S. / Caulfuty, M. / Wiszniewski, L. | 2009
TCDD induces dermal accumulation of keratinocyte-derived matrix metalloproteinase-10 in an organotypic model of human skin
Allen-Hoffmann, L. / De Abrew, N. / Rasmussen, C. / Bolterstein, E. / Schlosser, S. / Thomas-Virnig, C. | 2009
The cellular uptake of binary actin-ADP-ribosylating toxins from Clostridia depends on cyclophilin A
Kaiser, E. / Dukart, I. / Kroll, C. / Popoff, M. R. / Barth, H. | 2009
FOXO transcription factors and their role in overcoming doxorubicin-resistance of cancer cells
Chovolou, Y. / Beermann, A. / Lupertz, R. / Watjen, W. / Kampkotter, A. / Kahl, R. | 2009
Evaluation of spermatotoxicity of halogenated propanes by utilizing of mitochondrial metabolism in rat and comparison with the other test methods
Ohtani, K. / Kubota, H. | 2009
Methyl-parathion bioactivation in the male reproductive tract: From mRNA to protein expression of involved CYP isoforms
Quintanilla-Vega, B. / Espiritu-Gordillo, P. / Palacios-Gil, Y. / Guaderrama-Diaz, M. / Solis-Heredia, M. d. / Maldonado-Vazquez, W. / Lopez-Gonzalez, M. d. / Sierra-Santoyo, A. | 2009
Alterations of MMPs and TIMPs expression levels in an experimental rat model of resistive breathing
Noussia, O. / Toumpanakis, D. / Sigala, I. / Roussos, C. / Vassilakopoulos, T. / Theocharis, S. | 2009
Kinetics of benzo(a)pyrene and 3-hydroxybenzo(a)pyrene in relation to DNA adducts formation in rat tissues following intravenous administration of the parent compound
Marie, C. / Bouchard, M. / Thuot, R. / Ravanat, J. L. / Maitre, A. / Viau, C. | 2009
Evaluation of mutagenicity effect of Tarragon extract and Artemisia draconculus L by comet assay and comparison with sodium dichromate Cr(VI)
Kalantari, H. / Galedari, H. / Zareei, Z. | 2009
Detection of non specific organophosphate pesticide metabolites in human hair samples
Tzatzarakis, M. / Tutudaki, M. / Dawson, A. / Fahim, A. C. / Kokkinakis, M. / Maravgakis, G. / Tsatsakis, A. | 2009
Ag and TiO2 nanoparticles induce oxidative stress in A549 cells
Autrup, H. / Foldberg, R. / Deng, F. / Dang, D. A. / Olesen, P. | 2009
Adverse effects of nanoparticulate metal oxides in neuronal cells in vitro characterized by means of X-ray fluorescence and FTIR microspectroscopy
Kretlow, A. / Seiler, A. / Haase, A. / Luch, A. | 2009
Comparison of the blood levels of PCBs between fetuses and infants with longer lactational period in Japan
Mori, C. / Fukata, H. | 2009
Bioavailability of heavy metals and apoptotic effects on the midgut cells of Pseudaletia unipuncta (Lepidoptera: Noctuidae) inhabiting volcanic environments
Garcia, P. V. / Cunha, L. / Amaral, A. / Rodrigues, A. | 2009
Pb and Cd in autopsy tissues
Rubio, C. / Hernandez, C. / Delgado, F. G. / Sola, M. L. / Weller, D. G. / Gutierrez, A. J. / Hardisson, A. | 2009
Gasoline exposure effect on professionals in El-Minya Governorate in Upper Egypt (2007-2008)
Ibrahim, K. / Ahmed, S. | 2009
Risk assessment of cadmium in food: Implications for human health
Heppner, C. / Akesson, A. / Amzal, B. / Di Domenico, A. / Dorne, J. L. / Cristoph, E. H. / Galli, C. L. / Grandjean, P. / Jarup, L. / Gzyl, J. | 2009
Cardiac ion channel safety screening with the CytoPatch instrument
Scheel, O. / Rascher-Eggstein, G. / Knott, T. | 2009
Analysing discordant local lymph node assay datasets: Implications for reach
Basketter, D. / Ball, N. / Cagen, S. / Carrillo, J. C. / Certa, H. / Eigler, D. / Esch, H. / Garcia, C. / Graham, C. / Haux, C. | 2009
The effect of diazinon on rat brain antioxidant system
Salehi, M. / Jafari, M. / Moqadam, M. S. / Salimian, M. / Asghari, A. / Nateghi, M. / Abasnejad, M. / Haggholamali, M. | 2009
Genotoxicity of Di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate and prevention by selenium compounds in prostatic cell lines
Erkekoglu, P. / Rachidi, W. / Giray, B. / Hincal, F. | 2009
Genotoxic impurities: Safety in a Pandoras box?
Goldfain-Blanc, F. / Wattrelos, O. / Lorge, E. / Gervais, V. / Gignoux, C. / Claude, N. | 2009
Risk assessment of di-isobutyl phthalate and di-n-butyl phthalate in food
Wolfle, D. / Pfaff, K. / Platzek, T. / Luch, A. | 2009
Metabolic activation of nitroaromatics and arylamines
Stiborova, M. | 2009
Principles of characterizing and applying physiologically based pharmacokinetic models-An introduction
Meek, B. | 2009
Lung fibrosis is uncoupled from inflammation in response to toxic nano- and micro-particles
Huaux, F. / Re, S. L. / Lecocq, M. / Rabolli, V. / Giordano, G. / Muller, J. / Barbarin, V. / Lison, D. | 2009
Development of an in vitro liver toxicity prediction model based on longer term primary rat hepatocyte cultures
Hrach, J. / Hewitt, P. | 2009
Aldosterone causes DNA damage in vitro and in kidneys of DOCA/salt rats, mediated by the mineralocorticoid receptor
Schupp, N. / Kolkhof, P. / Queisser, N. / Barfacker, L. / Kretschmer, A. / Hartmann, E. / Schafer, S. / Stopper, H. | 2009
Chlorpyrifos induces apoptosis in murine thymocytes
Prakash, A. / Khan, S. / Aggarwal, M. / Telang, A. G. / Malik, J. K. | 2009
Nano- and microscaled titanium dioxide: Comparative study on the inflammatory and genotoxic effects after a 3-week inhalation in rats
Creutzenberg, O. / Pohlmann, G. / Hansen, T. / Rittinghausen, S. / Taugner, F. / Ziemann, C. | 2009
Carbon nanoparticles do not aggravate respiratory allergy induced by TMA in rats
Staal, Y. / van Triel, J. / Duistermaat, E. / Muijser, H. / Kuper, F. / Arts, J. | 2009
Small quaternary AChE inhibitors-Implication for pretreatment of OP poisoning or MG treatment
Musilek, K. / Komloova, M. / Holas, O. / Pohanka, M. / Opletalova, V. / Dolezal, M. / Kuca, K. | 2009
Read-across approach in the risk assessment of ferrochromium. Case: Repeated dose toxicity
Stockmann-Juvala, H. / Zitting, A. / Darrie, G. / Wallinder, I. O. / Santonen, T. | 2009
Proposal of a new carcinogenic toxicological reference value (TRV) for inhalation exposure to 1,2-dichloroethane
Laurent, B. / Cecilia, S. / Alain-Claude, R. / Michel, F. / Jean-Ulrich, M. / Brigitte, E. / Christophe, R. | 2009
Psychopharmacological properties of the pyridoindole derivative SMe1EC2
Mach, M. / Ujhazy, E. / Dubovicky, M. | 2009
Prediction of mutagenicity based on empirical physicochemical descriptors
Aires-de-Sousa, J. | 2009
Living with and without the maintenance cytosine methyltransferase, Dnmt1
Meehan, R. | 2009
Potency and trends of contact sensitisation in humans with regard to consumer products
Andersen, K. E. | 2009
An in vitro test strategy for predicting human acute toxicity
Blaauboer, B. J. | 2009
Botulinum Neurotoxin transgenic zebrafish for dissecting neuronal circuits in vivo and creating novel variants for neurotherapeutics
Suster, M. / Kawakami, K. | 2009
Molecular profiling of human kidney injury using antibody suspension bead arrays
Hedberg, J. / Neiman, M. / Donnes, P. / Uhlen, M. / Schwenk, J. / Nilsson, P. | 2009
D01
| 2009
Analysis of the therapeutic effect of Ginkgo biloba on liver damage produced by carbon tetrachloride in adult male rats
Posadas del Rio, F. A. / Chavez-Morales, R. M. / Rodriguez-Vazquez, M. L. / Jaramillo-Juarez, F. / Martinez-Saldana, M. C. / Olmos-Guerrero, C. E. / Reyes-Romero, M. A. | 2009
Assessment of the potency of contact allergens by using IL-8 release and p38 MAPK activation in THP-1 cells
Mitjans, M. / Marinovich, M. / Lucchi, L. / Galli, C. L. / Corsini, E. | 2009
Alterations of liver FAK and Src levels in the animal model of thioacetamide-induced fulminant hepatic failure and encephalopathy
Toumpanakis, D. / Zarros, A. / Zira, A. / Stolakis, V. / Chatzizacharias, N. / Vassilakopoulos, T. / Theocharis, S. | 2009
Evaluation of alternative endpoints for non-radioactive local lymph node assay by using two strong sensitizers
Ulker, O. C. / Karakaya, A. | 2009
Mixed contamination-induced metallothionein response in the Carassius carassius from the Upper Dnister River Basin, Ukraine
Stoliar, O. / Falfushynska, H. / Gnatyshyna, L. / Pryjdun, K. / Nam, Y. K. | 2009
Monitoring of coliform indicator removal in educational hospitals wastewater treatment plants in Sari City
Mohseni-Bandpei, A. / Yousefi, Z. / Ziaee, H. | 2009
Determination of metallothionein in various tissues of Danio rerio exposed to cisplatin
Soukupova, I. / Bojanovska, H. / Krystofova, O. / Adam, V. / Kizek, R. / Beklova, M. | 2009
All-trans retinoic acid induces breast cancer resistance protein expression in Caco-2 cells and enhances the transport of benzo[a]pyrene-3-sulfate
Hessel, S. / John, A. / Seidel, A. / Lampen, A. | 2009
The use of assessment factors and the implicit safety margins in occupational exposure limits
Schenk, L. | 2009
Histopathological examinations of the kidney of mice following phenol administration
Tootian, Z. / Fazelipour, S. / Monfared, A. L. | 2009
Mitochondrial effects of chloramphenicol and linezolid in HepG2 cells
Hoschele, D. / Wiertz, M. | 2009
Information resources for disaster response from the US National Library of Medicine
Goshorn, J. | 2009
Cross study comparison of three compounds causing kidney proximal tubule damage by combining omics data and conventional toxicological endpoints
Matheis, K. / Sposny, A. / Com, E. / Gautier, J. C. / Mally, A. / Hoffmann, D. / Kalkuhl, A. / Riefke, B. / Boernson, O. / Amberg, A. | 2009
Inhibition of male rat hepatic testosterone metabolism by modulation of androgenic signalling and castration
Freyberger, A. / Schladt, L. / Schmidt, U. / Krotlinger, F. / Andrews, P. | 2009
Dioxin-estrogen transcriptional interaction in lung cancer cell lines expressing different receptor phenotypes
Li, L. A. / Kuo, L. C. / Cheng, L. C. / Lin, S. F. | 2009
Chemical and enzymatic oxidation of 2-hydroxynevirapine, a metabolite of the HIV-1 reverse transcriptase inhibitor nevirapine
Marques, M. M. / Sidarus, M. C. / Beland, F. A. / Antunes, A. M. | 2009
New toxicity mechanisms of toxins produced by cyanobacteria in water blooms: Disruption of intercellular communication and modulation of estrogen receptor
Blaha, L. / Hilscherova, K. / Bartova, K. / Sidlova, T. / Babica, P. / Upham, B. | 2009
Involvement of caspase-8, -9, and -3 in high glucose-induced apoptosis in PC12 cells
Sharifi, A. M. / Eslami, H. / Larijani, B. / Davoodi, J. | 2009
Acute toxicity of diepoxybutane to human mononuclear lymphocytes
Ponte, F. / Carvalho, F. / Porto, B. | 2009
Metabolism of M1 and M2 vinclozolin metabolites by rat liver microsomes
Sierra-Santoyo, A. / de Oca, G. G. / Rosales-Loera, M. / Lopez-Gonzalez, L. | 2009
Effect of setarud (IMOD) as a new herbal drug on stereptozotocine-induced diabetes
Sadeghi, H. / Salehi Monfared, S. S. / Habibollahzadeh, E. / Khademi, Y. / Abdollahi, M. | 2009
Respiratory toxicology and immunotoxicology in human precision cut lung slices (PCLS)
Sewald, K. / Switalla, S. / Wang, L. / Pfennig, O. / Forster, C. / Krug, N. / Braun, A. | 2009
A suggestion of "Healthy School" with low volatile organic compounds (VOCs)
Hanazato, M. / Todaka, E. / Nakaoka, H. / Seto, H. / Mori, C. | 2009
Validation of an analytical methodology for determination of oxytetracycline residue in milk by HPLC with UV detection
Bakhtiarian, A. / Khosrokhavar, R. / Hosseini, M. J. | 2009
Micronuclei in peripheral blood lymphocytes in formaldehyde occupationally exposed workers
Ladeira, C. / Viegas, S. / Prista, J. / Malta-Vacas, J. / Gomes, M. / Mendonca, P. / Brito, M. | 2009
Toxicity of degradation products of refrigerants
Ema, M. / Naya, M. / Yoshida, K. / Nagaosa, R. | 2009
Preclinical evaluation of the immunological safety of biologics
Descotes, J. | 2009
Special aspects: Local kinetics
Pelkonen, O. | 2009
Regulation of ABC transporter genes
Elferink, R. O. | 2009
Ambient air particulate matter: A cause of airway and systemic disease
Morawska, L. | 2009
Pharmaceuticals in the environment: Issues in balancing human health benefits with ecological risks
Calow, P. | 2009
The rapid generation of PBPK models: A tool for good modelling practice
Loizou, G. | 2009
The antidiabetic Metformin is toxic to liver mitochondria of Zucker diabetic fatty (ZDF) rats: A cellular metabolomic study with 13C-lactate and carbon 13 NMR
Baverel, G. / Pinteur, C. / Martin, G. / Gauthier, C. | 2009
Comparison of toxic effects on CHO-KL and VERO cells after individual and combined treatment with Fusarium mycotoxins, beauvericin, deoxynivalenol and the T-2 toxin
Font, G. / Franzova, P. / Macakova, P. / Juan-Garcia, A. / Ruiz, M. J. | 2009
Increase in expiratory time is characteristic of the respiratory response in rat to toxic doses of methadone and fentanyl but not morphine and buprenorphine
Chevillard, L. | 2009
Acute toxicity effect of paraoxon on kidney lipid peroxidation and antioxidant system
Abbasnezhad, M. / Jafari, M. / HagHooseni, R. / Haggholamali, M. / Salehi, M. / Salimian, M. | 2009
Transcriptome analysis of contact-inhibition
Dietrich, C. / Ittrich, C. / Al-Butmeh, F. / Faust, D. / Kuppers, M. | 2009
Biomarkers of nephrotoxicity: Advancing from animal studies to human clinical trials
Eisinger, D. / Kusters, S. | 2009
Evaluation of FSH, LH, total testosterone and PSA levels in highly boron exposed workers in Turkey
Duydu, Y. / Aydn, S. / Ustundag, A. / Undeger, U. / Duker, Y. / Basaran, N. | 2009
Biomonitoring of metal contaminants in coastal zone of Ondo State, Nigeria: Fuzzy logic modelling approach
Agunbiade, F. / Olu-Owolabi, B. / Adebowale, K. | 2009
Development of a tiered set of modelling tools for derivation of biomonitoring guidance values
Bartels, M. / Loizou, G. / Price, P. / Spendiff, M. / Arnold, S. / Cocker, J. / Ball, N. | 2009
Mycotoxin rubratoxin B causes fatty acid oxidation disorder (FAOD) like symptoms in mice
Nagashima, H. | 2009
Metal-induced autoimmunity
Monestier, M. | 2009
Special considerations in safety pharmacology: Biologicals
Vargas, H. M. | 2009
The scientific basis and application of the threshold of toxicological concern (TTC)
Renwick, A. | 2009
Epoxide hydrolases: Structures, functions, mechanisms and toxicological implications
Arand, M. | 2009
Identification of a cycloisoemericellin derivative as a novel mycotoxin in Aspergillus nidulans
Muller, M. / Handrich, C. / Quitschau, M. / Bunger, J. / Westphal, G. / Hallier, E. / Grond, S. | 2009
Development of a human lung model system for the identification of chemical respiratory allergens in vitro
Szameit, S. / Farmer, L. / Hopfner, C. / Singal, M. / Jones, L. / Smith, L. / Weber, E. | 2009
A g-type phospholipase A2 inhibitor from Bothrops jararacussu snake plasma
Oliveira, C. Z. | 2009
Lipid peroxidation levels and antioxidant enzyme activities in hypertensive uremic patients undergoing hemodialysis
Giray, B. / Palabiyik, S. / Asci, A. / Cetinkaya, R. / Sahin, G. | 2009
Assessment of protective ability of epicatechin conjugates against peroxidative insult
Ugartondo, V. / Torres, J. L. / Mitjans, M. / Vinardell, M. P. | 2009
Biodegradation capability of some species of fungi isolated from contamined soils towards herbicides
Ouahiba, B. / Fatiha, B. / Regine, S. | 2009
Occurrence of fumonisins in corn, some corn based foods and wheat products in Egypt
Salem, D. A. / Ramadan, B. R. | 2009
In silico prediction of in vivo toxicities (eTox)-The Innovative Medicines Initiative Approach
Steger-Hartmann, T. / Pognan, F. / Sanz, F. / Diaz, C. A. | 2009
IFC Editorial Board
| 2009
Development of an in vitro test system to identify compounds with cell transforming activity
Thierbach, R. / Blume, U. / Steinberg, P. | 2009
Influence of different ways of euthanasia on the activity of cholinesterases in the rat
Novotny, L. / Zdarova, J. K. / Kuca, K. / Misik, J. / Bajgar, J. | 2009
Assessing combination effects of amphetamine designer drugs
da Silva, D. D. / Silva, R. / Remiao, F. / Carvalho, F. / de Lourdes Bastos, M. / Silva, E. / Carmo, H. | 2009
Drug metabolizing enzyme activity of in vitro human dermal (EpiDerm) and airway (EpiAirway) epithelial models: Relationship to genotoxicity of chemicals as determined by in vitro skin micronucleus assays
Kaluzhny, Y. / Letasiova, S. / Hayden, P. / Bolmarcich, J. / Jackson, G. / Klausner, M. | 2009
Changes in expression of GPX and SOD in mice treated with chronic doses of cyclophosphamide
Hassan, A. / Oraby, H. | 2009
Toxicogenomic response of azinphos-methyl treated zebrafish embryos and implication for the development of predictive models for chronic (fish) toxicity
Kluver, N. / Scheffler, K. / Renner, P. / Scholz, S. | 2009
Methadone-induced respiratory depression in rats is related to mu-1 and delta-mediated increase in expiratory time
Chevillard, L. | 2009
Transitioning to mode of action based testing: The critical role of frameworks for human relevance analysis of modes of action
Meek, B. | 2009
The effect of HI-6 on cholinesterases and on the cholinergic system of the rat bladder
Soukup, O. / Pohanka, M. / Tobin, G. / Kuca, K. | 2009
Effect of flavonoids on metabolism and excretion of PAHs in Caco-2 cell line
Bothe, H. / Niestroy, J. | 2009
Marine natural compounds modulate intracellular signalling pathways, apoptosis and oxidative stress in mammalian cells
Watjen, W. / Ruhl, S. / Rohrig, R. / Schmitz, R. / Bergermann, A. / Chovolou, Y. / Kampkotter, A. / Proksch, P. / Kahl, R. | 2009
Influence of nifedipine on cocaine elimination, after multiple administration in rats
Vitcheva, V. / Karova, D. / Mitcheva, M. | 2009
Circadian timing for cancer treatments
Levi, F. | 2009
Investigations on enhanced toxicity of methylated quercetin derivatives
Ruhl, S. / Rohrig, R. / Bothe, H. / Chovolou, Y. / Kampkotter, A. / Kahl, R. / Abel, J. / Proksch, P. / Watjen, W. | 2009
DNA methylation of GSTP1, a promising biomarker in early detection of prostate cancer
Dumache, R. / Puiu, M. / Canciu, C. / Cucu, N. | 2009
The golden therapy for Alzheimers disease targeting the angiotensin-converting enzyme and the cyclooxygenase-2 isoform
El-Sayed, N. / Kassem, L. / Heikal, O. | 2009
Comparative pulmonary toxicity study of different size of crystalline silica in rats: Micron vs. nano-size
Naya, M. / Kobayashi, N. / Ema, M. / Nakanishi, J. | 2009
Subacute oral toxicity study of zinc oxide nanopowder
Che, J. H. / You, J. R. / Seok, S. H. / Jang, J. J. / Kang, B. C. | 2009
Toxic effect of heavy metals (Chromium and Cadmium) combined to marine toxin (Okadaic Acid) on Caco2 cells
Ghada, S. | 2009
Estrogenic activity of the heavy metal cadmium in female rats is dose and route dependent
Hofer, N. / Diel, P. / Wilhelm, M. / Wittsiepe, J. / Degen, G. H. | 2009
Effects of human AS3MT genetic polymorphisms on arsenic metabolism in Taiwanese
Li, W. F. / Sun, C. W. / Liao, Y. T. / Chen, C. J. / Wang, S. L. | 2009
Changes in bone tissue composition, dimension and biomechanical properties of rat following in utero and lactational exposure to a mixture of environmental contaminants detected in Canadian Arctic human populations
Elabbas, L. / Finnila, M. A. / Herlin, M. / Stern, N. / Trossvik, C. / Bowers, J. W. / Chu, I. / Tuukkanen, J. / Akesson, A. / Hakansson, H. | 2009
Identification of atropine and scopolamine by HPLC in buckwheat flour contamination with Datura stramonium seeds
Rancic, D. / Spasic, A. | 2009
Effect of IL-6 polymorphism on autopsy kidney metal levels
Yalcin, S. / Kayaalti, Z. / Iritas, S. B. / Karakus, A. / Soylemezoglu, T. | 2009
In vitro methods for testing the biocompatibility of humic substances
Klocking, H. P. / Junek, R. / Schubert, R. / Klocking, R. | 2009
meta-Synephrine induces oxidative stress in freshly isolated cardiomyocytes
Rossato, L. G. / Carmo, H. / Carvalho, F. / de Lourdes Bastos, M. / Costa, V. M. / Remiao, F. | 2009
Transgenic mice for human sulfotransferases with polymorphic SULT1A genes
Wend, K. / Dobbernack, G. / Meinl, W. / Himmelbauer, H. / Glatt, H. | 2009
Perinatal tissue distribution of perfluorooctane sulphonate (PFOS) in mice
Borg, D. / Bogdanska, J. / Sundstrom, M. / Nobel, S. / Hakansson, H. / Bergman, A. / DePierre, J. / Halldin, K. / Bergstrom, U. | 2009
Mercury exposure and effects in 6-11-year-old children living in the area of the former mercury mine in Slovenia
Tratnik, J. / Briski, A. / Horvat, M. / Kobal, A. B. / Krsnik, M. / Mazej, D. / Osredkar, J. | 2009
Perinatal Aroclor 1254 exposure modulates polar and apolar retinoid levels in tissue and life-stage specific manners
Javier, E. / Elabbas, L. / Giese, N. / Bowers, W. J. / Chu, I. / Hamscher, G. / Hakansson, H. | 2009
Low levels of arsenic enhance the genotoxicity induced by ochratoxin A in human urothelial (5637) cells
Aggarwal, M. / Behm, C. / Foellmann, W. / Dorn, S. B. / Malik, J. K. / Degen, G. H. | 2009
Evaluation of the feasibility of juvenile toxicity study in the Gottingen Minipig
Chevalier, G. / Forster, R. / Bouchez, C. | 2009
The effects of addictive drugs on micronucleus frequency in humans
Akay, C. / Soykut, B. / Eken, A. / Erdem, O. / Sayal, A. / Aydin, A. / Cetin, M. K. / Dilbaz, N. | 2009
Immunotoxicology of very small molecules: Nanomedicines and nanomaterials
Descotes, J. | 2009
Effects of silymarin on the spontaneous proliferation and cell cycle of human peripheral blood leukemia T cells
Amirghofran, Z. / Garagozloo, M. | 2009
Nitrogen mustard (melphalan) exposure of an in vitro coculture model in the human proximal respiratory system
Pohl, C. / Moisch, M. / Hofmann, H. / Papritz, M. / Wubbeke, C. / Hermanns, I. / Kirkpatrick, C. J. / Kehe, K. | 2009
Effects of silver ions in aquatic and terrestrial organisms
Peckova, L. / Beklova, M. / Ostra, M. / Pikula, J. / Rauscherova, L. | 2009
Subchronic exposure of the common carp (Cyprinus carpio) to four herbicide formulations: Effect on the haematological indice
Haluzova, I. / Modra, H. / Mikula, P. / Svobodova, Z. | 2009
Effects of benzimidazole fungicides, benomyl and carbendazim, on lipid peroxidation and antioxidant system in rat
Alpertunga, B. / Catalgol, B. / Catalgol, S. | 2009
Genotoxic effects of Cd, Co and Pb on cultures of human lung cells after single and combined application
Wiese, J. / Glahn, F. / Foth, H. | 2009
Ochratoxin A: Is it present in human breast milk samples obtained mothers from Ankara, Turkey
Gurbay, A. / Girgin, G. / Sabuncuoglu, S. A. / Sahin, G. / Yurdakok, M. / Yigit, S. / Tekinalp, G. | 2009
Improving the assessment of risks from dietary exposures by modeling variation and uncertainty in exposure and dose response using linked exposure and PBPK/PD models
Price, P. / Schnelle, K. / Poet, T. / Hinderliter, P. | 2009
Pharmacoepidemiologic investigation regarding the interactions between antihypertensive medication and alcohol
Tartau, L. / Teslariu, E. / Duma, O. | 2009
Application of (Q)SAR and in vitro testing within the framework of REACH
Louekari, K. | 2009
TSNA adducts in smokers, nonsmokers and snuffers
Richter, E. / Holzle, D. / Schlobe, D. / Heling, A. K. / Heppel, C. / Eggert, H. | 2009
Trisk: European advanced risk assessors accredited training programme for highly qualified toxicology experts
Galli, C. L. / Hakansson, H. / Trice, S. / Blaauboer, B. J. / Kahl, R. / Gerevini, M. | 2009
Binary actin-ADP-ribosylating toxins: New insights into the interaction between bacterial toxins and host cell chaperones during internalization into mammalian cells
Barth, H. / Kaiser, E. | 2009
Role in ABC transporters in liver functions and disease
Schuetz, J. D. | 2009
Role of poison control centres in human data collection and dissemination of new treatment recommendations
Desel, H. | 2009
Cell specific action and toxicity of the AhR: Focus immune system
Esser, C. / Jux, B. / Kadow, S. / Chmill, S. / Hubinger, J. / Frericks, M. | 2009
Cross-omics comparison in toxicological research
Mally, A. | 2009
EFSAs risk assessment on PFOS and PFOA in the food
Johansson, N. / Benford, D. / Carere, A. / De Boer, J. / Dellatte, E. / De Voogt, P. / Di Domenico, A. / Heppner, C. W. / Schoeters, G. / Schrenk, D. | 2009
Kinetic glutathione chemoassay-A non-animal component of integrated testing strategies to identify compounds with an electrophilic potential for reactive toxicity
Bohme, A. / Thaens, D. / Paschke, A. / Schuurmann, G. | 2009
Modification and evaluation of the chicken embryotoxicity screening test (CHEST) as in vitro test system for embryotoxicity
Boehn, S. / Kamp, H. / Kaufmann, T. / Koch, M. / Wessa, P. / Landsiedel, R. / van Ravenzwaay, B. | 2009
Utility of StrataTest, an in vitro human skin model, for skin irritancy and corrosivity assessments
Gratz, K. / Rasmussen, C. / Comer, A. / Pirnstill, J. / Pirnstill, S. / Nataraj, P. / Simon, N. / Allen-Hoffmann, L. | 2009
Oxidative stress markers for monitoring secondary effects of rheumatoid arthritis treatments
Negrei, C. / Balalau, D. / Baconi, D. / Margina, D. / Ilie, M. / Balanescu, A. / Berghea, F. / Bojinca, V. / Opris, D. / Predeteanu, D. | 2009
Zebrafish as a toxicogenomic model system for testing the safety of new food ingredients
Rainieri, S. / Olasagasti, M. / Pardo, M. A. / Oyarbide, U. / Escuredo, K. | 2009
Cytotoxic and genotoxic effects of multi-walled carbon nanotubes on human bronchial normal cells (BEAS-2B)
Fanizza, C. / Paba, E. / Casciardi, S. / Marcelloni, A. M. / Pasquali, S. / Iavicoli, S. / Cavallo, D. | 2009
Heavy metals (Zn, Pb, Cd and Cr) in water, sediments and most consumed fishes sampled form Gorgan coast (Iran)
Saravi, S. S. / Shokrzadeh, M. | 2009
Determination of mercury and lead levels in autopsy brain tissue samples
Kaya, S. / Aliyev, V. / Iritas, S. B. / Soylemezoglu, T. | 2009
A new principle of pesticides bioidentification in fresh water
Tonkopii, V. | 2009
Allosteric interactions between terfenadine and chlorobutanol on hERG channels
Zunkler, B. / Friemel, A. | 2009
The OpenTox predictive toxicology framework
Hardy, B. | 2009
Role of ABC transporters at the blood-brain barrier
Potschka, H. | 2009
Pesticide exposure and risk of Parkinsons disease
Smith, L. | 2009
Assessing environmental effects of human pharmaceuticals
Boxall, A. B. | 2009
Inflammasomes-Danger sensing platforms controlling IL-1beta activation
Yazdi, A. | 2009
Classification of the model drug (ambroxol hydrochloride) into the Biopharmaceutics Classification System (BCS) and prediction of the intestinal transport using Caco-2 cells
Stetinova, V. / Smetanova, L. / Kholova, D. / Svoboda, Z. / Kvetina, J. | 2009
Adverse effects and drug interactions of herbal medicines
Basaran, N. / Basaran, A. A. | 2009
In vitro teratogenicity testing with zebrafish embryos combined with a mammalian metabolic activation system: Pros and cons
Broschard, T. / Weigt, S. | 2009
Effects of uranium on viability of human liver and kidney cells
Rouas, C. / Grandcolas, L. / Bensoussan, H. / Grison, S. / Stefani, J. / Gourmelon, P. / Pallardy, M. / Gueguen, Y. | 2009
Dose-dependent effect of carcinogens on gene expression in TK6 cells
Godderis, L. / McHale, C. / Hubbard, A. / Hoet, P. / Zhang, L. / Smith, M. / Veulemans, H. | 2009
Analysis of DNA binding of furan in rat liver by accelerator mass spectrometry
Hamberger, C. / Moro, S. / Malfatti, M. / Turteltaub, K. / Mally, A. / Dekant, W. | 2009
Refinement of TTC values: Identification of outliers in Cramer class 1-3
Tluczkiewicz, I. / Escher, S. / Bitsch, A. / Mangelsdorf, I. | 2009
Renal effects by a low and single dosis of nickel chloride in adult male rats
Jaramillo-Juarez, F. | 2009
Hexavalent chromium as a contaminant of food matrices: Its control in bread samples
Elisa Soares, M. / Vieira, E. / de Lourdes Bastos, M. | 2009
In vitro challenge using thymoquinone on (HepG2) cell line
Hassan, S. / Ahmed, W. A. / Galeb, F. M. / El-Taweel, M. A. | 2009
Editorial Board
| 2009
Introduction to World Health Organization globally harmonized risk assessment methodology
Vickers, C. | 2009
Molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer
Arlt, V. M. / Schmeiser, H. H. / Phillips, D. H. / Hollstein, M. | 2009
Cell-based in vitro alternatives to predict the contact and respiratory sensitizing potential of chemicals
Verstraelen, S. / Lambrechts, N. / Hooyberghs, J. / Nelissen, I. / Witters, H. / Schoeters, G. / Van Den Heuvel, R. | 2009
Hepatoprotective effects of Polygonum bistorta and active principles on albino rats intoxicated with carbon tetrachloride and paracetamol
Mittal, D. | 2009
Insulin-producing cells can be achieved in vitro by direct transfection of mouse pdx-1 into rat mesenchymal stem cells
Kadivar, M. / Memari, N. / Parivar, K. / Fard-Esfehani, P. | 2009
Toxic and inflammatory effects of particulate matter PM10 sampled during teaching hours in elementary school classrooms
Buters, J. / Oeder, S. / Weichenmeier, I. / Schober, W. / Dietrich, S. / Fromme, H. / Behrendt, H. | 2009
Comparative pulmonary toxicity of cadmium chloride on monoculture and co-culture of an in vitro alveolar barrier model
Cetin, Y. / Forti, E. / Prieto, P. | 2009
Development of a high-throughput keratinocyte-based standard assay to detect skin sensitizers based on ARE-dependent gene activity
Ellis, G. / Emter, R. / Natsch, A. | 2009
Metallothionein 2A core promoter region gene polymorphism and atherosclerosis disease
Kayaalti, Z. / Sahiner, M. L. / Soylemezoglu, T. | 2009
The study of analgesic effect of hydroalcoholic extract of Origanum vulgare in rat by formalin test
Arzi, A. / Aghel, N. / Khorasgani, Z. N. / Motahari, M. | 2009
The cytotoxicity and genotoxicity effect of cadmium on mice liver
Sani, M. J. / Mahmoudabady, A. Z. / Pur, M. A. / Sharifabady, R. R. / Bahadoran, H. / Jafari, A. / Rezavand, B. / Mohseni, A. / Montazeri, S. | 2009
Transcriptional response to neurotoxicants: Impact of gender, developmental stage and co-exposure on rat cerebellum and hippocampus gene expression following perinatal exposure
Pelletier, G. / Padhi, B. K. / Williams, A. | 2009
Involvement of cell proliferation and oxidative DNA damage in the process of hepatocellular hypertrophy induced by agricultural chemicals
Inoue, K. / Yoshida, M. / Takahashi, M. / Ozawa, S. / Nemoto, K. / Degawa, M. / Nishikawa, A. | 2009
Puerperium phase and aflatoxin M1 excretion in breast milk of selected mothers
Ortiz-Martinez, R. / Terrones-Saldivar, M. d. / Valdivia-Flores, A. / Quezada-Tristan, T. / Martinez-DeAnda, A. | 2009
Evaluation of indoor air quality by odor units (odor threshold ratio)
Seto, H. / Saitou, I. / Onuki, A. / Todaka, E. / Nakaoka, H. / Hanazato, M. / Mori, C. | 2009
Safety assessment of micro-organisms used as active ingredients in plant protection
Neurath, G. / Pfau, W. / Bieler, C. / Hauschild, R. | 2009
Effect of assimilable substrate and plant density on removal of phenol from water by Lemna minor
Tilaki, R. D. | 2009
Organochlorine pesticide residues in baby food products from Romania
Hura, C. / Hura, B. A. | 2009
Geochemical modelling of metals species in coastal water using PHREEQCI
Agunbiade, F. / Olu-Owolabi, B. / Adebowale, K. | 2009
Identification of target proteins of furan in rat liver
Moro, S. / Hamberger, C. / Dekant, W. / Kewin Chipman, J. / Mally, A. | 2009
Evaluation of health hazards by exposure to nickel in drinking water
Nielsen, E. | 2009
Monitoring methadone milk concentrations of methadone-maintained women in postpartum period for breastfeeding safety
Nikolaou, P. / Papoutsis, I. / Atta-Politou, J. / Athanaselis, S. / Spiliopoulou, C. / Maravelias, C. | 2009
Understanding and Applying Human Exposure Models: WHO guidance, with demonstration/case study of an exposure model
Heinemeyer, G. / Ozkaynak, H. | 2009
Computer tools for Threshold of Toxicological Concern elucidation
Jeliazkova, N. | 2009
Role of genotoxic and non-genotoxic mechanisms in furan carcinogenicity
Chipman, K. / Chen, T. / Hickling, K. / Dekant, W. / Mally, A. | 2009
Validation of the KLH assay in rats: A European collaborative study
Spanhaak, S. / Penninks, A. | 2009
Development of a quantitative detection system for cereulide, the emetic Bacillus cereus toxin
Bauer, T. / Stark, T. / Hofmann, T. / Ehling-Schulz, M. | 2009
Characterization of human cell line-based models for selective xenobiotic transport at the materno-fetal placental interface
Ritz, V. / Kneuer, C. / Gundert-Remy, U. / Hirsch-Ernst, K. I. | 2009
Experiences with the HET-CAM method in the routine testing of a broad variety of chemicals and formulations
Schrage, A. / Gamer, A. / van Ravenzwaay, B. / Landsiedel, R. | 2009
Effects of the mycotoxins aflatoxin B1, zearalenone and ochratoxine A on nuclear receptors PXR, CAR and AhR expression and corresponding CYP 450 in primary cultured human hepatocytes
Hassen, W. / Ayed-Boussema, I. / Pascussi, J. M. / Maurel, P. / Bacha, H. / Wafa, H. | 2009
Assessment of the lung deposition of particulates originating from diesel engines
Oravisjarvi, K. / Pietikainen, M. / Rautio, A. / Voutilainen, A. / Haataja, M. / Ruuskanen, J. / Keiski, R. L. | 2009
Tissue specific DNA damage in the European eel (Anguilla anguilla) following a short-term exposure to a glyphosate-based herbicide
Guilherme, S. / Gaivao, I. / Santos, M. A. / Pacheco, M. | 2009
Pathohistological evaluation of toxic effects of different oximes in rats
Jacevic, V. / Kuca, K. / Vukajlovic, A. / Milosavljevic, I. / Zolotarevski, L. | 2009
Application of quantitative structure-activity relationships (QSARs) for modeling drug and chemical transport across the human placenta barrier: A multivariate data analysis approach
Giaginis, C. / Zira, A. / Tsantili-Kakoulidou, A. / Theocharis, S. | 2009
Substances with endocrine disrupting properties under new EU plant protection product regulation-Establishment of assessment and decision criteria
Marx-Stoelting, P. / Chahoud, I. / Moeller, T. / Pfeil, R. / Solecki, R. / Ulbrich, B. / Hirsch-Ernst, K. I. | 2009
The aryl hydrocarbon receptor and cellular plasticity
Barouki, R. | 2009
Neuropathy target esterase in mouse embryonic stem cells
Pamies, D. / Villanova, E. / Sogorb, M. A. | 2009
Genotoxicological, biochemical and histological evaluations for the tricyclic antidepressant: Amitryptline on male albino mice
Hassanane, M. / Hafez, N. / Maksood, M. A. / El-Ghor, M. / Radwan, W. | 2009
Estimation of indoleamine 2,3-dioxygenase activity as kynurenine to tryptophan ratio in Turkish adolescents
Girgin, G. / Baydar, T. / Fuchs, D. / Derman, O. / Sahin, G. | 2009
Age related changes in the activity of selenoenzymes in mice-Interaction with chalcogen metalloids selenium and tellurium
Hodkova, A. / Kotyzova, D. / Eybl, V. | 2009
Effects of sub-chronic exposure to iridium on cytokines in female Wistar rats
Iavicoli, I. / Fontana, L. / Bergamaschi, A. | 2009
NanoTEST: Nanoparticle effects on placental function using in vitro toxicology
Cartwright, L. / Saunders, M. / Carreira, S. C. | 2009
In vitro toxicity of functionalized MWCNTs and Fullerenes on six mammalian cell lines: Selection and optimization of the proper method to reduce physical-chemical interferences
Bonafe, R. / Bardini, P. / Bussi, S. / Maiocchi, A. | 2009
Xenobiotic metabolism of bank vole (Myodes glareolus) exposed to PCDDs
Murtomaa, M. / Viitala, P. / Hokkanen, J. / Pelkonen, O. / Rautio, A. | 2009
Dog poisonings caused by Nodularia spumigena
Kruger, T. / Mundt, S. / Broker, D. / Luckas, B. | 2009
Polycyclic aromatic hydrocarbons in consumer products-Metabolism and toxicity in human skin
Stolpmann, K. / Henkler, F. / Hutzler, C. / Desai, D. / Amin, S. / Luch, A. | 2009
Applicability domain of TTC (Threshold of Toxicological Concern) schemes-A conceptual approach
Schuurmann, G. / Ebert, R. U. / Escher, S. / Mangelsdorf, I. / Kuhne, R. | 2009
Epigenetic changes in cancer as a signature of exposure to environmental and dietary factors
Herceg, Z. | 2009
Towards improvement in understanding hepatotoxicity using Omics
Mendrick, D. | 2009
Cytotoxic effects of hydroalcoholic extracts of Cucurbita pepo and Solanum nigrum compared with hydroalcoholic extract of Taxus baccata and cisplatin on normal and cancer cell lines
Shokrzadeh, M. / Saravi, S. S. | 2009
In vitro detection of pharmaceutical compounds that disturb mitochondrial functions
Edebert, I. / Rafter, I. | 2009
Effects of non-dioxin-like PCBs (NDL-PCBs) on signaling pathways contributing to liver tumor promotion and carcinogenesis
Machala, M. / Simeckova, P. / Al-Anati, L. / Stenius, U. / Pencikova, K. / Prochazkova, J. / Krcmar, P. / Slavik, J. / Vondracek, J. | 2009
Exposure assessments in nonclinical reproductive toxicology studies using toxicokinetics, including a novel approach for monitoring pre-/postnatal study exposures
Grizzle, T. | 2009
MicroRNA Biomarkers for Carcinogen Exposure in Rodents
Chen, T. | 2009
Determination of lethal dose (LD50) values in susceptible population of Helicoverpa armigera (Hubner) with the registered insecticides on cotton in Turkey
Ugurlu, S. | 2009
Safety of Azadirachtin
Pfau, W. / Bieler, C. / Neurath, G. | 2009
Effects of soaking and boiling, and autoclaving on anti-nutritional factors content of Mucuna flagellipes
Arisa, N. / Udensi, E. | 2009
Assessment factors for extrapolation from short-time to chronic exposure-Are the REACH guidelines adequate
Hansson, S. O. / Malkiewicz, K. / Ruden, C. | 2009
Clinical severity of acute carbamazepine poisonings: CNS depression and cardiotoxicity
Babic, G. / Stosic, J. J. / Vucinic, S. / Todorovic, V. | 2009
An oral (gavage) developmental neurotoxicity study of decabromodiphenyl oxide (DeBDPO) in rats
Jacobi, S. / Silberberg, H. / Stedeford, T. / Biesemeier, J. / Adriano, J. / Beck, M. | 2009
Application of the TTC concept on food packaging materials
Hollnagel, H. M. / Lehr, K. / Brands, B. | 2009
Colorectal cancer epigenetics: Causes, consequences and clinical applications
van Engeland, M. | 2009
Critical analysis of literature on low dose synergy for use of TTC in screening chemical mixtures for risk assessment
Boobis, A. / R. A. | 2009
Withdrawn
| 2009
Application of plant and earthworm bioassays to evaluate of toxicity effects of municipal sewage sludge
Sezimova, H. / Malachova, K. / Pavlickova, Z. / Sezima, T. | 2009
Biological leaching of metals from respirable tire wear particles
McAtee, B. / Sweet, L. / Panko, J. / Finley, B. | 2009