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1
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Diabetes and the Eye
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1
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Introduction to Diabetes in Older People
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1
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Physiological Responses to Exercise
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1
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The Diabetes Epidemic: Genes and Environment Clashing
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1
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The Public Health Impact of the Diabetes Epidemic
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13
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Risk Factors
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15
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Type 2 Diabetes Mellitus: Primary and Secondary Prevention the Vision of the International Diabetes Federation
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21
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Diabetes and the Kidney
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21
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Type 2 Diabetes Mellitus in Children and Adolescents
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22
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Managing Diabetes in Older People
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23
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Diabetic Nephropathy
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25
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Exercise in Type 1 Diabetes
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35
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Coronary Heart Disease and Diabetes
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41
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Screening for Undiagnosed Diabetes: Whom, Where, When and How
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45
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Diabetes and Cerebrovascular Disease
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45
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Diet and Nutritional Strategies during Sport and Exercise in Type 1 Diabetes
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49
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Diabetes and Foot Disease
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51
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Erectile Dysfunction
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59
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Evidence‐Based Interventions to Prevent or Retard Vascular Complications
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67
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The Role of Physical Activity in the Prevention of Type 2 Diabetes
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77
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Exercise, Metabolic Syndrome and Type 2 Diabetes
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79
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Classification and Clinical Features of Neuropathy
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79
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Diabetes and Autonomic Neuropathy
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81
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Genetic Screening and Prevention of Type 2 Diabetes
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85
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Pathophysiology of Diabetic Neuropathy
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91
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Epidemiology and Natural History of DPN
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93
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Developing Care Systems for Older People
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93
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Screening Parameters and Techniques: Limitations and Opportunities
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95
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Diabetes and Sexual Health
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95
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The Role of Exercise in the Management of Type 2 Diabetes
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97
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Detection/Screening/Assessment
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105
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Foot Ulceration and Charcot Arthropathy
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105
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Screening for Diabetes Mellitus – the World Health Organization Perspective
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107
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Exercise in Children and Adolescents
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113
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Short‐Term Complications of Diabetes
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113
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Treatments Options
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121
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Diabetes and the Heart
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121
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Insulin Pump Therapy and Exercise
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121
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Management Guidelines for Diabetic Peripheral Neuropathy and Foot Ulceration
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125
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Findings from Preventive Type 2 Diabetes Trials
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129
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Diabetic Retinopathy: Epidemiology and Risk Factors
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131
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Diabetes and the Marathon
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135
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Long‐Term Complications of Diabetes
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139
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Classification and Diagnosis of Diabetic Retinopathy
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143
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Diabetes and Specific Sports
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145
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Diabetes and the Brain
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151
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Diabetic Maculopathy
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153
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A Paradigm Shift is Needed in the Primary Prevention of Type 2 Diabetes
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161
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Becoming and Staying Physically Active
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163
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Proliferative Diabetic Retinopathy
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169
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Diabetes and the Gastrointestinal System
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169
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The Behaviour Change Process
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171
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Non‐Retinal Diabetic Ocular Complications
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179
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Pathophysiology and Potential Targets for Therapeutic Intervention
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179
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Preventive Disease Management – Risk Stratification as a New Tool in the Hands of General Practitioners
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189
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Educating and Communicating with Older People
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189
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Protein Kinase C
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193
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The Role of the Diabetes Team in Promoting Physical Activity
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197
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Protein Kinase C Activation and Vascular Permeability
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199
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Rehabilitation, Respite and Palliative Care
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203
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Diabetes and Musculoskeletal Disease
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203
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Prevention of Obesity and Lipid Disorders
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205
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Role of Protein Kinase C Activation in Cardiovascular and Renal Complications of Diabetes
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209
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Index
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211
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Mental Health, Depression, Dementia and Diabetes
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213
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Experimental Pharmacology using Isoform‐Selective Protein Kinase C Inhibitors
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215
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Diabetes and the Skin
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221
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Clinical Trials with Ruboxistaurin
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226
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Index
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230
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Effective Medication Management in Older People
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241
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Index
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245
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Renal Dysfunction and Hypertension, Focus on Type 2 Diabetes
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250
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Sexuality and Older People with Diabetes
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264
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Using Complementary Therapies Wisely in Older People
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271
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Diabetic Retinopathy in the 21st Century: Screening and Visual Outcomes
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283
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Resources
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285
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Prevention and Treatment of Diabetic Polyneuropathy (DPN)
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287
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Index
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313
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The Cardiologist's View: Prevention of Macrovascular Complications
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325
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Milestones and New Perspectives in Prevention of Type 2 Diabetes and Its Complications
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343
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Index
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Frontmatter
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Front Matter