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Muscle Aging, Inclusion‐Body Myositis and Myopathies [2012]
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Aging of the Human Neuromuscular System: Pathological Aspects
- 33
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Aging of the Human Neuromuscular System: Clinical Considerations
- 55
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Aging of the Human Neuromuscular System: Patient Vignettes
- 81
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Mitochondrial Changes in Aging with Particular Reference to Muscle, and Possible Clinical Consequences
- 89
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Protein Degradation in Aging Cells and Mitochondria: Relevance to the Neuromuscular System
- 97
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Human Muscle Protein Metabolism in Relation to Exercise and Aging: Potential Therapeutic Applications
- 109
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Pathogenesis of Sporadic Inclusion‐Body Myositis: Role of Aging and Muscle‐Fiber Degeneration, and Accumulation of the Same Proteins as in Alzheimer and Parkinson Brains
- 146
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Inflammatory and Autoimmune Features of Inclusion‐Body Myositis
- 159
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Sporadic Inclusion‐Body Myositis: Clinical Symptoms, Physical Findings, and Diagnostic Investigations
- 168
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Pathologic Diagnostic Criteria of Sporadic Inclusion‐Bodyc Myositis and Hereditary Inclusion‐Body Myopathy Muscle Biopsies
- 175
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Function and Mutations of the GNE Gene Leading to Distal Myopathy with Rimmed Vacuoles/Hereditary Inclusion‐Body Myopathy, Animal Models, and Potential Treatment
- 191
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GNE Myopathy (Hereditary Inclusion‐Body Myopathy/Distal Myopathy with Rimmed Vacuoles): Clinical Features and Epidemiology
- 199
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Consequences of the hereditary inclusion‐body myopathy‐characteristic GNE mutations on muscle proteins in vivo and in vitro
- 206
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Function and Structure of <fi>VCP</fi> Mutations Leading to Inclusion‐Body Myopathy Associated with Paget Disease of Bone and Frontotemporal Dementia
- 219
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Clinical Spectrum of VCP Myopathy, Paget Disease, and fronTotemporal Dementia: Experimental Models and Potential Treatments
- 230
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<fi>Drosophila</fi> and Mouse Models of Hereditary Myopathy Caused by Mutations in VCP/p97
- 241
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Index
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Colour Plates
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Front Matter