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1
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Fungal Molecular Pathogenesis: What Can It Do and Why Do We Need It?
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13
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Sex, <i>MAT</i>, and the Evolution of Fungal Virulence
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35
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Postgenomic Strategies for Genetic Analysis: Insight from <i>Saccharomyces cerevisiae</i> and <i>Candida albicans</i>
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45
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<i>Candida albicans</i> Hypha Formation and Virulence
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49
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The Conversion from Classical Studies in Fungal Pathogenesis to the Molecular Era
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71
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Mating and Parasexual Genetics in <i>Candida albicans</i>
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89
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The Mating‐Type Locus and Mating of <i>Candida albicans</i> and <i>Candida glabrata</i>
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113
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Evolution of Human‐Pathogenic Fungi: Phylogenies and Species
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133
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Establishment of Cell Identity in Pathogenic Fungi
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143
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Signal Transduction in the Interactions of Fungal Pathogens and Mammalian Hosts
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163
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Function and Regulation of Adhesin Gene Families in <i>Saccharomyces cerevisiae, Candida albicans</i>, and <i>Candida glabrata</i>
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177
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Fungal Biofilms: Agents of Disease and Drug Resistance
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187
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Molecular Basis of Fungal Adherence to Endothelial and Epithelial Cells
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197
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Molecular Principles of Antifungal Drug Resistance
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213
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Heterologous Hosts and the Evolution and Study of Fungal Pathogenesis
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227
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Amoeba and Slime Mold: Hosts of Virulence Evolution
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235
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<i>Aspergillus nidulans</i>: a Model for Elucidation of <i>Aspergillus fumigatus</i> Secondary Metabolism
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245
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<i>Saccharomyces cerevisiae</i>: an Emerging and Model Pathogenic Fungus
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261
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Fungal‐Bacterial Interactions
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271
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Amphibian Chytridiomycosis as an Emerging Infectious Disease of Wildlife: What Can We Learn from the Earliest Diverging Fungi?
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279
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<i>Cryptococcus neoformans</i> : a Sugar‐Coated Killer
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305
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Toward a Molecular Understanding of <i>Candida albicans</i> Virulence
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321
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Molecular Determinants of <i>Histoplasma capsulatum</i> Pathogenesis
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333
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Molecular Determinants of Virulence in <i>Aspergillus fumigatus</i>
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347
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Pathogenesis of <i>Pneumocystis</i>
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363
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Virulence Mechanisms of <i>Coccidioides</i>
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393
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<i>Blastomyces dermatitidis</i> Cell Surface Determinants and Their Application in Vaccine Development
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407
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Virulence Factors in Black Molds with Emphasis on Melanin, Chitin, and <i>Wangiella</i> as a Molecularly Tractable Model
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429
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Zygomycetes as Agents of Infectious Disease in Humans
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441
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Signaling Pathways in the Dimorphic Human Fungal Pathogen <i>Penicillium marneffei</i>
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455
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Innate Humoral Immunity to Fungi
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471
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Innate and Acquired Cellular Immunity to Fungi
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487
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Acquired Antibody‐Mediated Immunity to Fungi
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505
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Site‐Specific Mucosal Immunity to Fungi: Lessons Learned from <i>Candida albicans</i> Applied to Other Fungi
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527
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Intracellular Pathogenesis of <i>Histoplasma capsulatum</i>
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537
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Interactions of Immune Cells with the Facultative Intracellular Pathogen <i>Cryptococcus neoformans</i>
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555
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Fungal Interactions with Leukocytes
-
565
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Fungal Vaccine Development
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583
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Molecular Immunopathogenesis of Innate Host Defense against Chronic Disseminated (Hepatosplenic) Candidiasis
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589
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Studying Fungal Virulence by Using Genomics
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611
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Future of Functional Genomics of <i>Histoplasma capsulatum</i>
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627
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Functional Genomic Approaches to Fungal Pathogenesis, Drug Target Validation, and Antifungal Drug Discovery
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643
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Genetic and Proteomic Analysis of Fungal Virulence
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657
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Genomic Perspectives on the Fungal Kingdom
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667
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Index
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i
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Front Matter