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Molecular Principles of Fungal Pathogenesis [2006]

1
Fungal Molecular Pathogenesis: What Can It Do and Why Do We Need It?
13
Sex, <i>MAT</i>, and the Evolution of Fungal Virulence
35
Postgenomic Strategies for Genetic Analysis: Insight from <i>Saccharomyces cerevisiae</i> and <i>Candida albicans</i>
45
<i>Candida albicans</i> Hypha Formation and Virulence
49
The Conversion from Classical Studies in Fungal Pathogenesis to the Molecular Era
71
Mating and Parasexual Genetics in <i>Candida albicans</i>
89
The Mating‐Type Locus and Mating of <i>Candida albicans</i> and <i>Candida glabrata</i>
113
Evolution of Human‐Pathogenic Fungi: Phylogenies and Species
133
Establishment of Cell Identity in Pathogenic Fungi
143
Signal Transduction in the Interactions of Fungal Pathogens and Mammalian Hosts
163
Function and Regulation of Adhesin Gene Families in <i>Saccharomyces cerevisiae, Candida albicans</i>, and <i>Candida glabrata</i>
177
Fungal Biofilms: Agents of Disease and Drug Resistance
187
Molecular Basis of Fungal Adherence to Endothelial and Epithelial Cells
197
Molecular Principles of Antifungal Drug Resistance
213
Heterologous Hosts and the Evolution and Study of Fungal Pathogenesis
227
Amoeba and Slime Mold: Hosts of Virulence Evolution
235
<i>Aspergillus nidulans</i>: a Model for Elucidation of <i>Aspergillus fumigatus</i> Secondary Metabolism
245
<i>Saccharomyces cerevisiae</i>: an Emerging and Model Pathogenic Fungus
261
Fungal‐Bacterial Interactions
271
Amphibian Chytridiomycosis as an Emerging Infectious Disease of Wildlife: What Can We Learn from the Earliest Diverging Fungi?
279
<i>Cryptococcus neoformans</i> : a Sugar‐Coated Killer
305
Toward a Molecular Understanding of <i>Candida albicans</i> Virulence
321
Molecular Determinants of <i>Histoplasma capsulatum</i> Pathogenesis
333
Molecular Determinants of Virulence in <i>Aspergillus fumigatus</i>
347
Pathogenesis of <i>Pneumocystis</i>
363
Virulence Mechanisms of <i>Coccidioides</i>
393
<i>Blastomyces dermatitidis</i> Cell Surface Determinants and Their Application in Vaccine Development
407
Virulence Factors in Black Molds with Emphasis on Melanin, Chitin, and <i>Wangiella</i> as a Molecularly Tractable Model
429
Zygomycetes as Agents of Infectious Disease in Humans
441
Signaling Pathways in the Dimorphic Human Fungal Pathogen <i>Penicillium marneffei</i>
455
Innate Humoral Immunity to Fungi
471
Innate and Acquired Cellular Immunity to Fungi
487
Acquired Antibody‐Mediated Immunity to Fungi
505
Site‐Specific Mucosal Immunity to Fungi: Lessons Learned from <i>Candida albicans</i> Applied to Other Fungi
527
Intracellular Pathogenesis of <i>Histoplasma capsulatum</i>
537
Interactions of Immune Cells with the Facultative Intracellular Pathogen <i>Cryptococcus neoformans</i>
555
Fungal Interactions with Leukocytes
565
Fungal Vaccine Development
583
Molecular Immunopathogenesis of Innate Host Defense against Chronic Disseminated (Hepatosplenic) Candidiasis
589
Studying Fungal Virulence by Using Genomics
611
Future of Functional Genomics of <i>Histoplasma capsulatum</i>
627
Functional Genomic Approaches to Fungal Pathogenesis, Drug Target Validation, and Antifungal Drug Discovery
643
Genetic and Proteomic Analysis of Fungal Virulence
657
Genomic Perspectives on the Fungal Kingdom
667
Index
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Front Matter
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