BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS
Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
Inhaltsverzeichnis
- 3981
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Graphical contents list| 2009
- 3715
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Tetrahedron Young Investigator Award 2009: Carlos F. Barbas, III| 2009
- 3716
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An efficient chemical approach to bispecific antibodies and antibodies of high valencyGavrilyuk, Julia I. et al. | 2009
- 3721
-
Potential scorpionate antibiotics: Targeted hydrolysis of lipid II containing model membranes by vancomycin–TACzyme conjugates and modulation of their antibacterial activity by Zn-ionsBauke Albada, H. et al. | 2009
- 3725
-
Development of enzymatically cleavable prodrugs derived from dendritic polyglycerolCalderón, Marcelo et al. | 2009
- 3729
-
Dynamic kinetic asymmetric transfer hydrogenation of racemic 2,4-diaryl-2,3-dihydrobenzo[b][1,4]diazepines catalyzed by chiral phosphoric acidsHan, Zhi-Yong et al. | 2009
- 3733
-
Tra1 as a screening target for transcriptional activation domain discoveryMajmudar, Chinmay Y. et al. | 2009
- 3736
-
Identification of a β3-peptide HIV fusion inhibitor with improved potency in live cellsBautista, Arjel D. et al. | 2009
- 3739
-
Kinetic resolution of aliphatic acyclic β-hydroxyketones by recombinant whole-cell Baeyer–Villiger monooxygenases—Formation of enantiocomplementary regioisomeric estersRehdorf, Jessica et al. | 2009
- 3744
-
Improving the species cross-reactivity of an antibody using computational designFarady, Christopher J. et al. | 2009
- 3748
-
Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNAFurman, Jennifer L. et al. | 2009
- 3752
-
Using peptidyl aldehydes in activity-based proteomicsSabidó, Eduard et al. | 2009
- 3756
-
Identification of a disruptor of the MDM2-p53 protein–protein interaction facilitated by high-throughput in silico dockingLawrence, Harshani R. et al. | 2009
- 3760
-
Synthesis and SAR of C12–C13-oxazoline derivatives of epothilone APfeiffer, Bernhard et al. | 2009
- 3764
-
Brønsted acid-catalyzed Nazarov cyclization of pyrrole derivatives accelerated by microwave irradiationBachu, Prabhakar et al. | 2009
- 3767
-
Amino acid precursors for the detection of transketolase activity in Escherichia coli auxotrophsSimon, Grégory et al. | 2009
- 3771
-
Characterization of lassa virus cell entry inhibitors: Determination of the active enantiomer by asymmetric synthesisWhitby, Landon R. et al. | 2009
- 3775
-
Facile synthesis of cyclopeptide-centered multivalent glycoclusters with ‘click chemistry’ and molecular recognition study by surface plasmon resonanceChen, Yong-Xiang et al. | 2009
- 3779
-
CSI–FID: High throughput label-free detection of DNA binding moleculesHauschild, Karl E. et al. | 2009
- 3783
-
Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurationsKasper, Amanda C. et al. | 2009
- 3787
-
Synthesis and biological evaluation of penem inhibitors of bacterial signal peptidaseHarris, David A. et al. | 2009
- 3791
-
Predicting potential miRNA target sites within gene promotersYounger, Scott T. et al. | 2009
- 3795
-
Catalytic asymmetric synthesis of cyclic α-alkyl-amino acid derivatives having a tetrasubstituted α-carbonWang, Yong-Gang et al. | 2009
- 3798
-
Preparation of l-proline based aeruginosin 298-A analogs: Optimization of the P1-moietyWang, Guijun et al. | 2009
- 3804
-
Synthesis and reactivity of novel γ-phosphate modified ATP analoguesLee, Sarah E. et al. | 2009
- 3808
-
An improved synthesis of α,β-unsaturated nitrones relevant to the stephacidins and analogs thereofHafensteiner, Benjamin D. et al. | 2009
- 3811
-
Synthesis and evaluation of a netropsin–proximicin-hybrid library for DNA binding and cytotoxicityWolter, Falko E. et al. | 2009
- 3816
-
Resin-supported catalytic dendrimers as multivalent artificial metallonucleasesZaupa, Giovanni et al. | 2009
- 3821
-
Multiple catalytic aldolase antibodies suitable for chemical programmingGoswami, Rajib Kumar et al. | 2009
- 3825
-
Structure–activity relationship studies of small-molecule inhibitors of Wnt responseLu, Jianming et al. | 2009
- 3828
-
Identification of Hsp70 modulators through modeling of the substrate binding domainHaney, Conor M. et al. | 2009
- 3832
-
3-(Aminomethyl)piperazine-2,5-dione as a novel NMDA glycine site inhibitor from the chemical universe database GDBNguyen, Kong Thong et al. | 2009
- 3836
-
Synthesis of pochoxime prodrugs as potent HSP90 inhibitorsWang, Cuihua et al. | 2009
- 3841
-
Cyclic glycopeptidomimetics through a versatile sugar-based scaffoldAltamura, Maria et al. | 2009
- 3845
-
One plasmid selection system for the rapid evolution of aminoacyl-tRNA synthetasesMelançon, Charles E. et al. | 2009
- 3848
-
Hypervalent iodine-catalyzed oxylactonization of ketocarboxylic acids to ketolactonesUyanik, Muhammet et al. | 2009
- 3852
-
Efficient syntheses of chiral myo-inositol derivatives—key intermediates in glycosylphosphatidylinositol (GPI) synthesesYu, Fei et al. | 2009
- 3856
-
Asymmetric synthesis of β,γ-unsaturated α-amino acids via efficient kinetic resolution with cinchona alkaloidsHang, Jianfeng et al. | 2009
- 3859
-
Origin of the stability conferred upon collagen by fluorinationShoulders, Matthew D. et al. | 2009
- 3863
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Total synthesis and determination of the absolute configuration of FD-838, a naturally occurring azaspirobicyclic productHayashi, Yujiro et al. | 2009
- 3866
-
Rapid identification of improved protein ligands using peptoid microarraysLim, Hyun-Suk et al. | 2009
- 3870
-
Side-chain assisted ligation in protein synthesisAjish Kumar, K.S. et al. | 2009
- 3875
-
Efficient synthesis of Idraparinux, the anticoagulant pentasaccharideChen, Chen et al. | 2009
- 3880
-
Biomolecular assembly by iterative oxime ligationsRenaudet, Olivier et al. | 2009
- 3884
-
Homogeneous gold-catalyzed efficient oxidative dimerization of propargylic acetatesCui, Li et al. | 2009
- 3888
-
Organocatalysis with endogenous compounds: Towards novel non-enzymatic reactionsAlberg, David G. et al. | 2009
- 3892
-
A flexizyme that selectively charges amino acids activated by a water-friendly leaving groupNiwa, Nobuyoshi et al. | 2009
- 3895
-
Enantioselective Henry (nitroaldol) reaction catalyzed by axially chiral guanidinesUbe, Hitoshi et al. | 2009
- 3899
-
Highly efficient synthesis of vinyl substituted triazoles by Au(I) catalyzed alkyne activationDuan, Haifeng et al. | 2009
- 3903
-
Selective G-quadruplex ligands: The significant role of side chain charge density in a series of perylene derivativesMicheli, Emanuela et al. | 2009
- 3909
-
An enantioselective synthesis of (+)-(S)-[n]-gingerols via the l-proline-catalyzed aldol reactionMa, Shichao et al. | 2009
- 3912
-
Positioning of 99mTc-chelators influences radiolabeling, stability and biodistribution of Affibody moleculesEkblad, Torun et al. | 2009
- 3915
-
l-Prolinol as a highly enantioselective catalyst for Michael addition of cyclohexanone to nitroolefinsChua, Pei Juan et al. | 2009
- 3919
-
DNA sequence selectivity of hairpin polyamide turn unitsFarkas, Michelle E. et al. | 2009
- 3924
-
Selection of a buried salt bridge by phage displayVagt, Toni et al. | 2009
- 3928
-
Design and synthesis of novel hybrid benzamide–peptide histone deacetylase inhibitorsHu, Fang et al. | 2009
- 3932
-
A new synthesis of caged GABA compounds for studying GABAA receptorsFan, Lijun et al. | 2009
- 3934
-
Kinetic and mechanistic studies of proline-mediated direct intermolecular aldol reactionsZotova, Natalia et al. | 2009
- 3938
-
Organocatalytic synthesis and sterol 14α-demethylase binding interactions of enantioriched 3-(1H-1,2,4-triazol-1-yl)butyl benzoatesMing, Zhi-Hui et al. | 2009
- 3941
-
Inhibition of Pseudomonas aeruginosa quorum sensing by AI-2 analogsGanin, Hadas et al. | 2009
- 3945
-
Expedient solid-phase synthesis of both symmetric and asymmetric diol libraries targeting aspartic proteasesShi, Haibin et al. | 2009
- 3949
-
Catalyst-free tandem aldol condensation-Michael addition of 1,3-cyclohexanediones with enolizable aldehydesRohr, Kerstin et al. | 2009
- 3952
-
Organocatalytic enantioselective hetero-Diels–Alder reaction of aldehydes and o-benzoquinone diimide: Synthesis of optically active hydroquinoxalinesLi, Jun-Long et al. | 2009
- 3955
-
Organocatalytic α-hydroxymethylation of cyclopentanone with aqueous formaldehyde: Easy access to chiral δ-lactonesMase, Nobuyuki et al. | 2009
- 3959
-
Enzymatic activation of hydrophobic self-immolative dendrimers: The effect of reporters with ionizable functional groupsAvital-Shmilovici, Michal et al. | 2009
- 3963
-
Dendrimers ended by non-symmetrical azadiphosphonate groups: Synthesis and immunological propertiesMarchand, Patrice et al. | 2009
- 3967
-
Chiral N-phosphonyl imine chemistry: Asymmetric synthesis of α,β-diamino esters by reacting phosphonyl imines with glycine enolatesAi, Teng et al. | 2009
- 3970
-
Restricted spacer tolerance of a zinc finger nuclease with a six amino acid linkerShimizu, Yuka et al. | 2009
- 3973
-
Synthesis, configurational stability and stereochemical biological evaluations of (S)- and (R)-5-hydroxythalidomidesYamamoto, Takeshi et al. | 2009
- 3977
-
Synthesis and SAR study of novel pseudo-steroids as potent and selective progesterone receptor antagonistsJain, Nareshkumar et al. | 2009
- 4011
-
Dopamine D3 receptor antagonists: The quest for a potentially selective PET ligand. Part two: Lead optimizationMicheli, Fabrizio / Holmes, Ian / Arista, Luca et al. | 2009
- 4014
-
Discovery of a new class of catalytic topoisomerase II inhibitors targeting the ATP-binding site by structure based design. Part IFuret, Pascal / Schoepfer, Joseph / Radimerski, Thomas et al. | 2009
- 4018
-
Metal ion CHElate-aSSisted LIGAtion (CHESS LIGA) for SNP detection on microarraysHien, Le Thi / Oretskaya, Tatiana S. / Zatsepin, Timofei S. et al. | 2009
- 4022
-
The identification and optimisation of novel and selective diamide neuropeptide Y Y2 receptor antagonistsLunniss, Gillian E. / Barnes, Ashley A. / Barton, Nick et al. | 2009
- 4026
-
Structure–Activity Relationship of novel phenylacetic CXCR1 inhibitorsSablone, Manolo Rocco / Cesta, Maria Candida / Moriconi, Alessio et al. | 2009
- 4031
-
Conformationally restricted homotryptamines. Part 5: 3-(trans-2-aminomethylcyclopentyl)indoles as potent selective serotonin reuptake inhibitorsDenhart, Derek J. / Deskus, Jeffrey A. / Ditta, Jonathan L. et al. | 2009
- 4034
-
Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitorsShi, Yan / Zhang, Jing / Shi, Mengxiao et al. | 2009
- 4042
-
Identification of aminoethyl pyrrolo dihydroisoquinolinones as novel poly(ADP-ribose) polymerase-1 inhibitorsBranca, Danila / Cerretani, Mauro / Jones, Philip et al. | 2009
- 4046
-
Assessment of new 2prime-O-acetalester protecting groups for regular RNA synthesis and original 2prime-modified proRNAMartin, A. R. / Lavergne, T. / Vasseur, J. J. et al. | 2009
- 4046
-
Assessment of new 2′-O-acetalester protecting groups for regular RNA synthesis and original 2′-modified proRNAMartin, Anthony R. / Lavergne, Thomas / Vasseur, Jean-Jacques et al. | 2009
- 4050
-
Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)Miyashiro, Julie / Woods, Keith W. / Park, Chang H. et al. | 2009
- 4055
-
Synthesis and evaluation of 5-benzylidene(thio)barbiturate-β-d-glycosides as mushroom tyrosinase inhibitorsYan, Qin / Cao, Rihui / Yi, Wei et al. | 2009
- 4055
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Synthesis and evaluation of 5-benzylidene(thio)barbiturate-b-d-glycosides as mushroom tyrosinase inhibitorsYan, Q. / Cao, R. / Yi, W. et al. | 2009
- 4059
-
Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3)Kuduk, Scott D. / Chang, Ronald K. / Wai, Jenny M.-C. et al. | 2009
- 4064
-
Synthesis and fungicidal activity of 3,5-dichloropyrazin-2(1H)-one derivativesFrançois, Isabelle E.J.A. / Cammue, Bruno P.A. / Bresseleers, Sara et al. | 2009
- 4067
-
Bis-anthracenyl isoxazolyl amides have enhanced anticancer activityGajewski, Mariusz P. / Beall, Howard / Schnieder, Mark et al. | 2009
- 4070
-
Potent, orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitorsKoltun, Dmitry O. / Zilbershtein, Timur M. / Migulin, Vasily A. et al. | 2009
- 4075
-
Development of a selective and potent radioactive ligand for histamine H3 receptors: A compound potentially useful for receptor occupancy studiesMitobe, Yuko / Ito, Sayaka / Mizutani, Takashi et al. | 2009
- 4079
-
Synthesis of novel macrolide derivatives with imidazo[4,5-b]pyridinyl sulfur contained alkyl side chains and their antibacterial activityXu, Peng / Liu, Lu / Chen, Xiao-zhuo et al. | 2009
- 4084
-
Peperomins as anti-inflammatory agents that inhibit the NF-κB signaling pathwayTsutsui, Chieko / Yamada, Yuriko / Ando, Masayoshi et al. | 2009
- 4084
-
Peperomins as anti-inflammatory agents that inhibit the NF-kB signaling pathwayTsutsui, C. / Yamada, Y. / Ando, M. et al. | 2009
- 4088
-
Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitorsOwen, Dafydd R. / Walker, John K. / Jon Jacobsen, E. et al. | 2009
- 4092
-
Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring systemHughes, Robert O. / Walker, John K. / Cubbage, Jerry W. et al. | 2009
- 4097
-
Aminopiperidine-fused imidazoles as dipeptidyl peptidase-IV inhibitorsEdmondson, Scott D. / Mastracchio, Anthony / Cox, Jason M. et al. | 2009
- 4102
-
The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian α-carbonic anhydrase isoformsParkkila, Seppo / Innocenti, Alessio / Kallio, Heini et al. | 2009
- 4102
-
The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian a-carbonic anhydrase isoformsParkkila, S. / Innocenti, A. / Kallio, H. et al. | 2009
- 4107
-
7-Cycloalkylcamptothecin derivatives: Preparation and biological evaluationLi, Mingzong / Jin, Wei / Jiang, Chen et al. | 2009
- 4110
-
Tetrahydrocarbazole amides with potent activity against human papillomavirusesGudmundsson, Kristjan S. / Boggs, Sharon D. / Sebahar, Paul R. et al. | 2009
- 4115
-
Synthesis and evaluation of new endomorphin analogues modified at the Pro2 residueTorino, Domenica / Mollica, Adriano / Pinnen, Francesco et al. | 2009
- 4119
-
Synthesis of novel quinoxaline derivatives and its cytotoxic activitiesTanimori, Shinji / Nishimura, Takeshi / Kirihata, Mitsunori et al. | 2009
- 4122
-
Synthesis and evaluation of 3″- and 4″-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000Raju, Ravinder / Castillo, Bernard F. / Richardson, Stewart K. et al. | 2009
- 4122
-
Synthesis and evaluation of 3Prime- and 4Prime-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000Raju, R. / Castillo, B. F. / Richardson, S. K. et al. | 2009
- 4126
-
First steps in the direction of synthetic, allosteric, direct inhibitors of thrombin and factor XaVerghese, Jenson / Liang, Aiye / Sidhu, Preet Pal Singh et al. | 2009
- 4130
-
The synthesis and biological evaluation of a novel series of C7 non-basic substituted fluoroquinolones as antibacterial agentsHuang, Xiaoguang / Chen, Dongliang / Wu, Ning et al. | 2009
- 4134
-
Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitorsKang, Iou-Jiun / Wang, Li-Wen / Hsu, Sheng-Ju et al. | 2009
- 4139
-
Bisintercalator-containing dinuclear iron(III) complex: An efficient artificial nucleaseChen, Xiaoqiang / Fan, Jiangli / Peng, Xiaojun et al. | 2009
- 4143
-
Synthesis and antitumor activity of substituted triazolo[4,3-a]pyrimidin-6-sulfonamide with an incorporated thiazolidinone moietyHafez, Hend N. / El-Gazzar, Abdel-Rahman B.A. et al. | 2009
- 4148
-
Synthesis of calcium phosphate-binding liposome for drug deliveryAnada, Takahisa / Takeda, Yoichi / Honda, Yoshitomo et al. | 2009
- 4151
-
Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part I: Discovery of 3-(2-hydroxyethoxy)-4-methoxy-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamideUto, Yoshikazu / Ogata, Tsuneaki / Harada, Jun et al. | 2009
- 4159
-
Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part II: Identification of 4-ethylamino-3-(2-hydroxyethoxy)-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide and its biological evaluationUto, Yoshikazu / Ogata, Tsuneaki / Kiyotsuka, Yohei et al. | 2009
- 4167
-
Synthesis and evaluation of 1-(benzo[b]thiophen-2-yl)ethanone analogues as novel anti-osteoporosis agents acting on BMP-2 promotorLiu, Zong-ying / He, Xiao-bo / Yang, Zhao-yong et al. | 2009
- 4171
-
Regioselective synthesis of methylated epigallocatechin gallate via nitrobenzenesulfonyl (Ns) protecting groupAihara, Yoshiyuki / Yoshida, Atsusi / Furuta, Takumi et al. | 2009
- 4175
-
Real-time fluorescence monitoring of GSK3β-catalyzed phosphoryation by use of a BODIPY-based Zn(II)–Dpa chemosensorSakamoto, Takashi / Inoue, Masa-aki / Ojida, Akio et al. | 2009
- 4175
-
Real-time fluorescence monitoring of GSK3b-catalyzed phosphoryation by use of a BODIPY-based Zn(II)-Dpa chemosensorSakamoto, T. / Inoue, M. a. / Ojida, A. et al. | 2009
- 4178
-
N-[(Dihydroxyphenyl)acyl]serotonins as potent inhibitors of tyrosinase from mouse and human melanoma cellsYamazaki, Yoshimitsu / Kawano, Yasuhiro / Yamanaka, Akiko et al. | 2009
- 4183
-
Discovery and functional evaluation of diverse novel human CB1 receptor ligandsFoloppe, Nicolas / Benwell, Karen / Brooks, Teresa D. et al. | 2009
- 4191
-
Discovery of N-[(1-aryl-1H-indazol-5-yl)methyl]amides derivatives as smoothened antagonists for inhibition of the hedgehog pathwayDessole, Gabriella / Branca, Danila / Ferrigno, Federica et al. | 2009
- 4196
-
Identification of substituted pyrazolo[1,5-a]quinazolin-5(4H)-one as potent poly(ADP-ribose)polymerase-1 (PARP-1) inhibitorsOrvieto, Federica / Branca, Danila / Giomini, Claudia et al. | 2009
- 4201
-
Discovery of β-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IVNordhoff, Sonja / Cerezo-Gálvez, Silvia / Deppe, Holger et al. | 2009
- 4201
-
Discovery of b-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IVNordhoff, S. / Cerezo-Galvez, S. / Deppe, H. et al. | 2009
- 4204
-
Design, synthesis and biological evaluation of 2H-benzo[b][1,4] oxazine derivatives as hypoxia targeted compounds for cancer therapeuticsDas, Bhaskar C. / Madhukumar, Ankanahlli V. / Anguiano, Jaime et al. | 2009
- 4207
-
5-N,N-Disubstituted 5-aminopyrazole-3-carboxylic acids are highly potent agonists of GPR109bSkinner, Philip J. / Webb, Peter J. / Sage, Carleton R et al. | 2009
- 4210
-
Synthesis of 9-b-d-arabinofuranosylguanine by combined use of two whole cell biocatalystsMedici, R. / Iribarren, A. M. / Lewkowicz, E. S. et al. | 2009
- 4210
-
Synthesis of 9-β-d-arabinofuranosylguanine by combined use of two whole cell biocatalystsMédici, Rosario / Iribarren, Adolfo M. / Lewkowicz, Elizabeth S. et al. | 2009
- 4213
-
Design, synthesis and evaluation of aspirin analogues having an additional carboxylate substituent for antithrombotic activityAlagha, Ahmed / Moman, Edelmiro / Adamo, Mauro F.A. et al. | 2009
- 4217
-
First experimental identification of Ras-inhibitor binding interface using a water-soluble Ras ligandPalmioli, Alessandro / Sacco, Elena / Abraham, Sherwin et al. | 2009
- 4223
-
A stabilized demethoxyviridin derivative inhibits PI3 kinaseYuan, Hushan / Pupo, Monica T. / Blois, Joe et al. | 2009
- 4228
-
Application of a 3,3-diphenylpentane skeleton as a multi-template for creation of HMG-CoA reductase inhibitorsHosoda, Shinnosuke / Matsuda, Daisuke / Tomoda, Hiroshi et al. | 2009
- 4232
-
Synthesis, structure–activity relationships, and biological profiles of a dihydrobenzoxathiin class of histamine H3 receptor inverse agonistsSasaki, Takahide / Takahashi, Toshiyuki / Nagase, Tsuyoshi et al. | 2009
- 4237
-
Synthesis and antimultidrug resistance evaluation of icariin and its derivativesLiu, Dong-Fang / Li, Yan-Ping / Ou, Tian-Miao et al. | 2009
- 4241
-
Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureasHart, Terance / Macias, Alba T. / Benwell, Karen et al. | 2009
- 4245
-
N-(4-Fluorobenzyl)-3-hydroxy-9,9-dimethyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrazino[1,2-a]pyrimidine-2-carboxamides a novel class of potent HIV-1 integrase inhibitorsPetrocchi, Alessia / Jones, Philip / Rowley, Michael et al. | 2009
- 4250
-
The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4′-azidocytidine (R1479)McGuigan, Christopher / Kelleher, Mary Rose / Perrone, Plinio et al. | 2009
- 4250
-
The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4prime-azidocytidine (R1479)McGuigan, C. / Kelleher, M. R. / Perrone, P. et al. | 2009
- 4255
-
Induction of apoptosis in HuH-7 cancer cells by monoterpene and β-carboline indole alkaloids isolated from the leaves of Tabernaemontana elegansMansoor, Tayyab A. / Ramalho, Rita M. / Mulhovo, Silva et al. | 2009
- 4255
-
Induction of apoptosis in HuH-7 cancer cells by monoterpene and b-carboline indole alkaloids isolated from the leaves of Tabernaemontana elegansMansoor, T. A. / Ramalho, R. M. / Mulhovo, S. et al. | 2009
- 4259
-
Unsymmetrical non-adamantyl N,Nprime-diaryl urea and amide inhibitors of soluble expoxide hydrolaseAnandan, S. K. / Webb, H. K. / Do, Z. N. et al. | 2009
- 4259
-
Unsymmetrical non-adamantyl N,N′-diaryl urea and amide inhibitors of soluble expoxide hydrolaseAnandan, Sampath-Kumar / Webb, Heather K. / Do, Zung N. et al. | 2009
- 4264
-
Discovery and optimization of a novel Neuromedin B receptor antagonistFu, Jiasheng / Shuttleworth, Stephen J. / Connors, Richard V. et al. | 2009
- 4268
-
Optimization of 2-piperidin-4-yl-acetamides as melanin-concentrating hormone receptor 1 (MCH-R1) antagonists: Designing out hERG inhibitionBerglund, Susanne / Egner, Bryan J. / Gradén, Henrik et al. | 2009
- 4274
-
Optimization of piperidin-4-yl-urea-containing melanin-concentrating hormone receptor 1 (MCH-R1) antagonists: Reducing hERG-associated liabilitiesBerglund, Susanne / Egner, Bryan J. / Gradén, Henrik et al. | 2009
- 4280
-
Dipeptidyl nitrile inhibitors of Cathepsin LAsaad, Nabil / Bethel, Paul A. / Coulson, Michelle D. et al. | 2009
- 4284
-
Structure–activity relationship of etomidate derivatives at the GABAA receptor: Comparison with binding to 11β-hydroxylaseAtucha, Erika / Hammerschmidt, Friedrich / Zolle, Ilse et al. | 2009
- 4284
-
Structure-activity relationship of etomidate derivatives at the GABAA receptor: Comparison with binding to 11b-hydroxylaseAtucha, E. / Hammerschmidt, F. / Zolle, I. et al. | 2009
- 4288
-
Synthesis and biological activity of α-galactosyl ceramide KRN7000 and galactosyl (α1→2) galactosyl ceramideVeerapen, Natacha / Brigl, Manfred / Garg, Salil et al. | 2009
- 4288
-
Synthesis and biological activity of a-galactosyl ceramide KRN7000 and galactosyl (a12) galactosyl ceramideVeerapen, N. / Brigl, M. / Garg, S. et al. | 2009
- 4292
-
Discovery of novel aminothiadiazole amides as selective EP3 receptor antagonistsHilfiker, Mark A. / Wang, Ning / Hou, Xiaoping et al. | 2009
- 4296
-
Photochemical control of FlAsH labeling of proteinsWilkins, Bryan J. / Yang, Xu / Cropp, T. Ashton et al. | 2009
- 4299
-
Synthesis and structure–activity relationships of γ-carboline derivatives as potent and selective cysLT1 antagonistsBonjoch, Josep / Diaba, Faïza / Pagès, Lluís et al. | 2009
- 4299
-
Synthesis and structure-activity relationships of g-carboline derivatives as potent and selective cysLT1 antagonistsBonjoch, J. / Diaba, F. / Pages, L. et al. | 2009
- 4303
-
Pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione derivatives as novel small molecule chaperone amplifiersZhou, Yuefen / Wei, Linyi / Brady, Thomas P. et al. | 2009
- 4308
-
Potent agonists of the Hedgehog signaling pathwayBrunton, Shirley A. / Stibbard, John H.A. / Rubin, Lee L. et al. | 2009
- 4312
-
Structure–activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of actionBolognesi, Maria Laura / Bartolini, Manuela / Rosini, Michela et al. | 2009
- 4316
-
The phosphoramidate ProTide approach greatly enhances the activity of b-2prime-C-methylguanosine against hepatitis C virusMcGuigan, C. / Perrone, P. / Madela, K. et al. | 2009
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The phosphoramidate ProTide approach greatly enhances the activity of β-2′-C-methylguanosine against hepatitis C virusMcGuigan, Christopher / Perrone, Plinio / Madela, Karolina et al. | 2009
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Identification of compounds exhibiting inhibitory activity toward the Pseudomonas tolaasii toxin tolaasin I using in silico docking calculations, NMR binding assays, and in vitro hemolytic activity assaysLee, Younggiu / Woo, Yoonkyung / Lee, Soohyun et al. | 2009
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Optimization of a series of 2,4-diaminopyridines as neuropeptide Y Y1 receptor antagonists with reduced hERG activityKameda, Minoru / Kobayashi, Kensuke / Ito, Hirokatsu et al. | 2009
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Structure-based de novo design and biochemical evaluation of novel Cdc25 phosphatase inhibitorsPark, Hwangseo / Bahn, Young Jae / Ryu, Seong Eon et al. | 2009
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Fe(II) phthalocyanine catalyzed oxidation of dGMP by molecular oxygenKuznetsova, Aleksandra A. / Solovyeva, Lyudmila I. / Kaliya, Oleg L. et al. | 2009
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Identification of a chromone-based retinoid containing a polyolefinic side chain via facile synthetic routesSun, Weilin / Carroll, Patrick J. / Soprano, Dianne R. et al. | 2009
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[11C]PR04.MZ, a promising DAT ligand for low concentration imaging: Synthesis, efficient 11C-O-methylation and initial small animal PET studiesRiss, Patrick J. / Hooker, Jacob M. / Alexoff, David et al. | 2009
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Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-κB inhibitor, DMAPT (LC-1)Neelakantan, Sundar / Nasim, Shama / Guzman, Monica L. et al. | 2009
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Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-kB inhibitor, DMAPT (LC-1)Neelakantan, S. / Nasim, S. / Guzman, M. L. et al. | 2009
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Substituted benzothiadizine inhibitors of Hepatitis C virus polymeraseShaw, Antony N. / Tedesco, Rosanna / Bambal, Ramesh et al. | 2009
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Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitorsTedesco, Rosanna / Chai, Deping / Darcy, Michael G. et al. | 2009
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Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the α6∗ subtypeBreining, Scott R. / Bencherif, Merouane / Grady, Sharon R. et al. | 2009
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Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the a6* subtypeBreining, S. R. / Bencherif, M. / Grady, S. R. et al. | 2009
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Effect of varying chain length between P1 and P1′ position of tripeptidomimics on activity of angiotensin-converting enzyme inhibitorsChaudhary, Snehlata / Vats, Ishwar Dutt / Chopra, Madhu et al. | 2009
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Effect of varying chain length between P1 and P1prime position of tripeptidomimics on activity of angiotensin-converting enzyme inhibitorsChaudhary, S. / Vats, I. D. / Chopra, M. et al. | 2009
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Antitumor activity of deoxypodophyllotoxin isolated from Anthriscus sylvestris: Induction of G2/M cell cycle arrest and caspase-dependent apoptosisYong, Yeonjoong / Shin, Soon Young / Lee, Young Han et al. | 2009
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Structure-based virtual screening approach to identify novel classes of Cdc25B phosphatase inhibitorsPark, Hwangseo / Li, Minghua / Choi, Jungeun et al. | 2009
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Ionic interactions for substituted MCH1R inhibitors studied by pKa valuesLee, Joo Yun / Lee, Hyuk / Lim, Jung Yun et al. | 2009
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Brain-penetrating 2-aminobenzimidazole H1-antihistamines for the treatment of insomniaCoon, Timothy / Moree, Wilna J. / Li, Binfeng et al. | 2009