BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS
Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
Inhaltsverzeichnis
- 3391
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Graphical contents list| 2015
- 3409
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Regulating the master regulator: Controlling heat shock factor 1 as a chemotherapy approachMcConnell, Jeanette R. / Buckton, Laura K. / McAlpine, Shelli R. et al. | 2015
- 3415
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The structural use of carbostyril in physiologically active substancesTashima, Toshihiko et al. | 2015
- 3420
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Cyclin dependent kinase (CDK) inhibitors as anticancer drugsSánchez-Martínez, Concepción / Gelbert, Lawrence M. / Lallena, María José et al. | 2015
- 3436
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Discovery and optimization of a highly efficacious class of 5-aryl-2-aminopyridines as FMS-like tyrosine kinase 3 (FLT3) inhibitorsLiu, Gang / Abraham, Sunny / Liu, Xing et al. | 2015
- 3442
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Discovery of new acetylcholinesterase inhibitors with small core structures through shape-based virtual screeningChen, Yao / Liu, Zong-liang / Fu, Ting-ming et al. | 2015
- 3447
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Activity of aminoferrocene-based prodrugs against prostate cancerSchikora, Margot / Reznikov, Alexander / Chaykovskaya, Liudmila et al. | 2015
- 3451
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C4 phenyl aporphines with selective h5-HT2B receptor affinityKapadia, Nirav / Harding, Wayne W. et al. | 2015
- 3455
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Benzylated and prenylated flavonoids from the root barks of Cudrania tricuspidata with pancreatic lipase inhibitory activityJo, Yang Hee / Kim, Seon Beom / Liu, Qing et al. | 2015
- 3458
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Hybrid pyrimidine alkynyls inhibit the clinically resistance related Bcr-AblT315I mutantLu, Xiaoyun / Zhang, Zhang / Ren, Xiaomei et al. | 2015
- 3464
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Novel inhibitor against Malassezia globosa LIP1 (SMG1), a potential anti-dandruff targetGuo, Shaohua / Huang, Wenkang / Zhang, Jian et al. | 2015
- 3468
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Synthesis of ciprofloxacin dimers for evaluation of bacterial permeability in atypical chemical spaceRoss, Audrey G. / Benton, Bret M. / Chin, Donovan et al. | 2015
- 3476
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Targeted fluorescent probes for detection of oxidative stress in the mitochondriaYapici, Nazmiye B. / Mandalapu, Srinivas / Michael Gibson, K. et al. | 2015
- 3481
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Human SIRT3 tripeptidic inhibitors containing Nε-thioacetyl-lysineChen, Bing / Wang, Juan / Huang, Yajun et al. | 2015
- 3488
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Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeysFischer, Christian / Zultanski, Susan L. / Zhou, Hua et al. | 2015
- 3495
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Potent benzoazepinone γ-secretase modulators with improved bioavailabilityMethot, Joey L. / Fischer, Christian / Li, Chaomin et al. | 2015
- 3501
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Discovery of 11β-hydroxysteroid dehydrogenase type 1 inhibitorHong, Sung Pyo / Nam, Ky Youb / Shin, Young June et al. | 2015
- 3507
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The selectivity of 6-nor-ABA and 7′-nor-ABA for abscisic acid receptor subtypesTakeuchi, Jun / Ohnishi, Toshiyuki / Okamoto, Masanori et al. | 2015
- 3511
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Synthesis and antiproliferative activity of new bioconjugates of Salinomycin with amino acid estersAntoszczak, Michał / Sobusiak, Maria / Maj, Ewa et al. | 2015
- 3515
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Further optimization of the mGlu5 PAM clinical candidate VU0409551/JNJ-46778212: Progress and challenges towards a back-up compoundZhou, Ya / Malosh, Chrysa / Conde-Ceide, Susana et al. | 2015
- 3520
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Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonistsLai, Zhong / He, Shuwen / Sherer, Edward C. et al. | 2015
- 3526
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Quinolizidine alkaloids reduced mortality in EV71-infected mice by compensating for the levels of T cellsYang, Yajun / Guan, Feifei / Bai, Lin et al. | 2015
- 3529
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Geraniin inhibits TGF-β1-induced epithelial–mesenchymal transition and suppresses A549 lung cancer migration, invasion and anoikis resistanceKo, Hyeonseok et al. | 2015
- 3535
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Novel hybrids of 3-n-butylphthalide and edaravone: Design, synthesis and evaluations as potential anti-ischemic stroke agentsSheng, Xiao / Hua, Kai / Yang, Chunyu et al. | 2015
- 3541
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Hedgehog inhibitors from Withania somniferaYoneyama, Tatsuro / Arai, Midori A. / Sadhu, Samir K. et al. | 2015
- 3545
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Metronidazole hydrazone conjugates: Design, synthesis, antiamoebic and molecular docking studiesAnsari, Mohammad Fawad / Siddiqui, Shadab Miyan / Agarwal, Subhash M. et al. | 2015
- 3550
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Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktisVullo, Daniela / De Luca, Viviana / Del Prete, Sonia et al. | 2015
- 3556
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Monoterpene indole alkaloid hydrazone derivatives with apoptosis inducing activity in human HCT116 colon and HepG2 liver carcinoma cellsPaterna, Angela / Borralho, Pedro M. / Gomes, Sofia E. et al. | 2015
- 3560
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Synthesis of the aggregation pheromone of the Colorado potato beetle from its degradation productWacławczyk-Biedroń, Weronika / Frąckowiak-Wojtasek, Bożena / Strub, Daniel et al. | 2015
- 3564
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The 2′,4′-dihydroxychalcone could be explored to develop new inhibitors against the glycerol-3-phosphate dehydrogenase from Leishmania speciesPassalacqua, Thais G. / Torres, Fábio A.E. / Nogueira, Camila T. et al. | 2015
- 3569
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Identification and optimisation of a 4′,5-bisthiazole series of selective phosphatidylinositol-3 kinase alpha inhibitorsFairhurst, Robin A. / Imbach-Weese, Patricia / Gerspacher, Marc et al. | 2015
- 3575
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Identification and optimisation of 4,5-dihydrobenzo[1,2-d:3,4-d]bisthiazole and 4,5-dihydrothiazolo[4,5-h]quinazoline series of selective phosphatidylinositol-3 kinase alpha inhibitorsFairhurst, Robin A. / Gerspacher, Marc / Imbach-Weese, Patricia et al. | 2015
- 3582
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Discovery of a novel tricyclic 4H-thiazolo[5′,4′:4,5]pyrano[2,3-c]pyridine-2-amino scaffold and its application in a PI3Kα inhibitor with high PI3K isoform selectivity and potent cellular activityGerspacher, Marc / Fairhurst, Robin A. / Mah, Robert et al. | 2015
- 3585
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The discovery of oxazolones-grafted spirooxindoles via three-component diversity oriented synthesis and their preliminary biological evaluationDong, Hui / Song, Sicheng / Li, Jingjing et al. | 2015
- 3592
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Anticancer effect and mechanism of a Se-modified porphyrin Au(III) complexYang, Feng-Rui / Li, Yue / Zhang, Xiao-Hong et al. | 2015
- 3597
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Synthesis and cytotoxic properties of tryptamine derivativesSalikov, Rinat F. / Belyy, Aleksandr Yu. / Khusnutdinova, Nailya S. et al. | 2015
- 3601
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Synthesis and anticancer activity of novel curcumin–quinolone hybridsRaghavan, Saiharish / Manogaran, Prasath / Gadepalli Narasimha, Krishna Kumari et al. | 2015
- 3606
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Lipid-lowering polyketides from a soft coral-derived fungus Cladosporium sp. TZP29Zhu, Meilin / Gao, Huquan / Wu, Chongming et al. | 2015
- 3610
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Synthesis of novel cationic spermine-conjugated phosphotriester oligonucleotide for improvement of cell membrane permeabilityHayashi, Junsuke / Hamada, Tomoko / Sasaki, Ikumi et al. | 2015
- 3616
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Antiproliferative and tumor inhibitory studies of 2,3 disubstituted 4-thiazolidinone derivativesSharath Kumar, Kothanahally S. / Hanumappa, Ananda / Vetrivel, Maruthai et al. | 2015
- 3621
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Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53–MDM2 interaction with a distinct binding modeGessier, François / Kallen, Joerg / Jacoby, Edgar et al. | 2015
- 3626
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Ligand efficient tetrahydro-pyrazolopyridines as inhibitors of ERK2 kinaseBagdanoff, Jeffrey T. / Jain, Rama / Han, Wooseok et al. | 2015
- 3630
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Structure activity relationship of C-2 ether substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-5)Singh, Sheo B. / Kaelin, David E. / Meinke, Peter T. et al. | 2015
- 3636
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Structure activity relationship of pyridoxazinone substituted RHS analogs of oxabicyclooctane-linked 1,5-naphthyridinyl novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-6)Singh, Sheo B. / Kaelin, David E. / Wu, Jin et al. | 2015
- 3644
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Discovery, design, and synthesis of indole-based EZH2 inhibitorsGehling, Victor S. / Vaswani, Rishi G. / Nasveschuk, Christopher G. et al. | 2015
- 3650
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Synthesis and anti-tubercular activity of 2-nitroimidazooxazines with modification at the C-7 position as PA-824 analogsKang, Young-Goo / Park, Chan-Yong / Shin, Hongsuk et al. | 2015
- 3654
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3-Hydroxy-4-pyridinone derivatives designed for fluorescence studies to determine interaction with amyloid protein as well as cell permeabilityTelpoukhovskaia, Maria A. / Cawthray, Jacqueline F. / Rodríguez-Rodríguez, Cristina et al. | 2015
- 3658
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Cell-free expression with the toxic amino acid canavanineWorst, Emanuel G. / Exner, Matthias P. / De Simone, Alessandro et al. | 2015
- 3661
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Biarylsulfonamide CCR9 inhibitors for inflammatory bowel diseaseZhang, Jing / Romero, Jan / Chan, Audrey et al. | 2015
- 3665
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Discovery of a 6-(pyridin-3-yl)benzo[d]thiazole template for optimization of hedgehog and PI3K/AKT/mTOR dual inhibitorsYang, Zhaohui / Ma, Haikuo / Sun, Zhijian et al. | 2015
- 3671
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Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screeningDoddaramappa, Shridevi D. / Lokanatha Rai, K.M. / Srikantamurthy, Ningaiah et al. | 2015
- 3676
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Discovery of non-competitive thrombin inhibitor derived from competitive tryptase inhibitor skeleton: Shift in molecular recognition resulted from skeletal conversion of carboxylate into phosphonateAoyama, Hiroshi / Ijuin, Ryosuke / Kato, Jun-ya et al. | 2015
- 3681
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AzaHx, a novel fluorescent, DNA minor groove and G·C recognition element: Synthesis and DNA binding properties of a p-anisyl-4-aza-benzimidazole-pyrrole-imidazole (azaHx-PI) polyamideSatam, Vijay / Babu, Balaji / Patil, Pravin et al. | 2015
- 3686
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New geranylated flavanones from the fruits of Paulownia catalpifolia Gong Tong with their anti-proliferative activity on lung cancer cells A549Gao, Tian-yang / Jin, Xing / Tang, Wen-zhao et al. | 2015
- 3690
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Structure–activity relationship of N-benzenesulfonyl matrinic acid derivatives as a novel class of coxsackievirus B3 inhibitorsWang, Sheng-Gang / Kong, Lan-Ying / Li, Ying-Hong et al. | 2015
- 3694
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Synthesis and biological evaluation of N-cyclopropylbenzamide-benzophenone hybrids as novel and selective p38 mitogen activated protein kinase (MAPK) inhibitorsHeo, Jinyuk / Shin, Hanbo / Lee, Jun et al. | 2015
- 3699
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Design and biological evaluation of novel quinolone-based metronidazole derivatives as potent Cu2+ mediated DNA-targeting antibacterial agentsZhang, Ling / Kumar, Kannekanti Vijaya / Geng, Rong-Xia et al. | 2015
- 3706
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Design and synthesis of constrained analogs of LCRF-0004 as potent RON tyrosine kinase inhibitorsRaeppel, Stéphane L. / Therrien, Eric / Raeppel, Franck et al. | 2015
- 3711
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Design, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitorsBoucle, Sebastien / Tao, Sijia / Amblard, Franck et al. | 2015
- 3716
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Discovery of tripeptide-derived multifunctional ligands possessing delta/mu opioid receptor agonist and neurokinin 1 receptor antagonist activitiesNair, Padma / Yamamoto, Takashi / Cowell, Scott et al. | 2015
- 3721
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Exploration on natural product anibamine side chain modification toward development of novel CCR5 antagonists and potential anti-prostate cancer agentsXu, Guoyan G. / Zaidi, Saheem A. / Zhang, Feng et al. | 2015
- 3726
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Synthesis and cytotoxic activities of 2-substituted (25R)-spirostan-1,4,6-triene-3-ones via ring-opening/elimination and ‘click’ strategyLu, Xiao-Feng / Yang, Zheng / Huang, Nian-Yu et al. | 2015
- 3730
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Design, synthesis and evaluation of benzotriazole derivatives as novel antifungal agentsShah, Jay J. / Khedkar, Vijay / Coutinho, Evans C. et al. | 2015
- 3738
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Discovery of 2-arylamino-4-(1-methyl-3-isopropylsulfonyl-4-pyrazol-amino)pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitorsZhang, Peilong / Dong, Jiaqiang / Zhong, Boyu et al. | 2015
- 3744
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Dendritic hexadecapeptide as a cathepsin B degradable carrier for delivery of HSP90 inhibitorKolhatkar, Vidula / Suárez, Jose / Kolhatkar, Rohit et al. | 2015
- 3748
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Discovery of a novel 2,3,11,11a-tetrahydro-1H-pyrazino[1,2-b]isoquinoline-1,4(6H)-dione series promoting neurogenesis of human neural progenitor cellsLin, Hong / Fang, Haiyan / Wang, Jamie et al. | 2015
- 3754
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Corrigendum to “Synthesis and cytotoxicity of 3,4-disubstituted-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazoles and novel 5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives bearing 3,4,5-trimethoxyphenyl moiety” [Bioorg. Med. Chem. Lett. 22/13 (2012) 4471–4474]Zhao, Pei-Liang / Duan, An-Na / Zou, Min et al. | 2015
- 3755
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Corrigendum to “Development of methyl isoxazoleazepines as inhibitors of BET” [Bioorg. Med. Chem. Lett. 25/9 (2015) 1842–1848]Hewitt, Michael C. / Leblanc, Yves / Gehling, Victor S. et al. | 2015
- IFC
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Editorial board| 2015