BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS
Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
Inhaltsverzeichnis
- 6207
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Graphical contents list| 2011
- 6228
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The successful quest for oral factor Xa inhibitors; learnings for all of medicinal chemistry?Young, Robert J. et al. | 2011
- 6236
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BRN-103, a novel nicotinamide derivative, inhibits VEGF-induced angiogenesis and proliferation in human umbilical vein endothelial cellsChoi, Hye-Eun / Yoo, Min-Sang / Choi, Jung-Hye et al. | 2011
- 6242
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Stable and orally bio-available pro-drugs of CPS11Huo, Aihong / Zhang, Hesheng / Guan, Yongbiao et al. | 2011
- 6245
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Synthesis and evaluation of cytotoxic effects of hanultarin and its derivativesLee, Eunyoung / Ahamed, V.S. Jamal / Kumar, Mahto Sanjeev et al. | 2011
- 6249
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Design and synthesis of a library of chemokine antagonistsBhalay, Gurdip / Albrecht, Birgit / Akhlaq, Mohammed et al. | 2011
- 6253
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Indolin-2-one p38α inhibitors III: Bioisosteric amide replacementEastwood, Paul / González, Jacob / Gómez, Elena et al. | 2011
- 6253
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Indolin-2-one p38a inhibitors III: Bioisosteric amide replacementEastwood, P. / Gonzalez, J. / Gomez, E. et al. | 2011
- 6258
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Imidazo[1,5-a]quinoxalines as irreversible BTK inhibitors for the treatment of rheumatoid arthritisKim, Kyung-Hee / Maderna, Andreas / Schnute, Mark E. et al. | 2011
- 6264
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Discovery of 1-arylcarbonyl-6,7-dimethoxyisoquinoline derivatives as glutamine fructose-6-phosphate amidotransferase (GFAT) inhibitorsQian, Yimin / Ahmad, Mushtaq / Chen, Shaoqing et al. | 2011
- 6270
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Cytotoxic and antivascular 1-methyl-4-(3-fluoro-4-methoxyphenyl)-5-(halophenyl)-imidazolesBiersack, Bernhard / Muthukumar, Yazh / Schobert, Rainer et al. | 2011
- 6274
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Mepyramine–JNJ7777120-hybrid compounds show high affinity to hH1R, but low affinity to hH4RWagner, Eva / Wittmann, Hans-Joachim / Elz, Sigurd et al. | 2011
- 6281
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Cell fingerprint patterns using designed a-helical peptides to screen for cell-specific toxicityUsui, K. / Kakiyama, T. / Tomizaki, K. y. et al. | 2011
- 6281
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Cell fingerprint patterns using designed α-helical peptides to screen for cell-specific toxicityUsui, Kenji / Kakiyama, Takashi / Tomizaki, Kin-ya et al. | 2011
- 6285
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Synthesis and properties of novel 2′-O-alkoxymethyl-modified nucleic acidsArai, Koichiro / Uchiyama, Naoki / Wada, Takeshi et al. | 2011
- 6285
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Synthesis and properties of novel 2prime-O-alkoxymethyl-modified nucleic acidsArai, K. / Uchiyama, N. / Wada, T. et al. | 2011
- 6288
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Substituted indole-1-acetic acids as potent and selective CRTh2 antagonists—discovery of AZD1981Luker, Tim / Bonnert, Roger / Brough, Steve et al. | 2011
- 6293
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Design and synthesis of biotinylated DHMEQ for direct identification of its target NF-κB componentsSaitoh, Tsuyoshi / Takeiri, Masatoshi / Gotoh, Yuko et al. | 2011
- 6293
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Design and synthesis of biotinylated DHMEQ for direct identification of its target NF-kB componentsSaitoh, T. / Takeiri, M. / Gotoh, Y. et al. | 2011
- 6297
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Design, synthesis and insight into the structure–activity relationship of 1,3-disubstituted indazoles as novel HIF-1 inhibitorsAn, Hongchan / Kim, Nam-Jung / Jung, Jong-Wha et al. | 2011
- 6301
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Synthesis, stereochemistry and in vitro antimicrobial evaluation of novel 2-[(2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ylidene)hydrazono]-4-phenyl-2,3-dihydrothiazolesRamachandran, Rajamanickam / Parthiban, Paramasivam / Rani, Mannangatty et al. | 2011
- 6305
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Identification of novel plasmin inhibitors possessing nitrile moiety as warheadTeno, Naoki / Gohda, Keigo / Wanaka, Keiko et al. | 2011
- 6310
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Tetrahydroquinolines as a novel series of nonsteroidal selective androgen receptor modulators: Structural requirements for better physicochemical and biological propertiesNagata, Naoya / Miyakawa, Motonori / Amano, Seiji et al. | 2011
- 6314
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Design, synthesis, and structure–activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitorsYamashita, Tohru / Kamata, Makoto / Endo, Satoshi et al. | 2011
- 6319
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Biological evaluation of glycosyl-isoindigo derivatives against the pathogenic agents of tropical diseases (malaria, Chagas disease, leishmaniasis and human African trypanosomiasis)Bouchikhi, Fadoua / Anizon, Fabrice / Brun, Reto et al. | 2011
- 6322
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2-Oxo-N-aryl-1,2,3,4-tetrahydroquinoline-6-sulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinaseWalsh, Martin J. / Brimacombe, Kyle R. / Veith, Henrike et al. | 2011
- 6328
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Antiviral activity of novel 2prime-fluoro-6prime-methylene-carbocyclic adenosine against wild-type and drug-resistant hepatitis B virus mutantsWang, J. / Singh, U. S. / Rawal, R. K. et al. | 2011
- 6328
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Antiviral activity of novel 2′-fluoro-6′-methylene-carbocyclic adenosine against wild-type and drug-resistant hepatitis B virus mutantsWang, Jianing / Singh, Uma S. / Rawal, Ravindra K. et al. | 2011
- 6332
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PEGylation enhances the therapeutic potential of peptide antagonists of the neonatal Fc receptor, FcRnMezo, Adam R. / Low, Susan C. / Hoehn, Todd et al. | 2011
- 6336
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Synthesis, pharmacophore modeling and in vitro activity of 10,11-dihydrodibenzo[b,f]oxepine-4-carboxamide derivatives as novel and potent antagonists of the prostaglandin EP4 receptorStasi, Luigi Piero / Bhimani, Kanji / Borriello, Manuela et al. | 2011
- 6341
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Polarization in the structures of uracil and thiouracils: Implication for binding with orotidine 5prime-monophosphate decarboxylaseHuang, S. / Gronert, S. / Wu, W. et al. | 2011
- 6341
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Polarization in the structures of uracil and thiouracils: Implication for binding with orotidine 5′-monophosphate decarboxylaseHuang, Sha / Gronert, Scott / Wu, Weiming et al. | 2011
- 6343
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Steroidal C-21 mercapto derivatives as dissociated steroids: Discovery of an inhaled dissociated steroidBiju, Purakkattle / McCormick, Kevin / Aslanian, Robert et al. | 2011
- 6348
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Investigation of the pyrazinones as PDE5 inhibitors: Evaluation of regioisomeric projections into the solvent regionHughes, Robert O. / Maddux, Todd / Joseph Rogier, D. et al. | 2011
- 6353
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Mode of action investigation for the antibacterial cationic anthraquinone analogsChan, Ka Yee / Zhang, Jianjun / Chang, Cheng-Wei Tom et al. | 2011
- 6357
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Utilizing G-quadruplex formation to target 8-oxoguanine in telomeric sequencesChitranshi, Priyanka / Xue, Liang et al. | 2011
- 6362
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Synthesis and evaluation of pyridazinone–phenethylamine derivatives as selective and orally bioavailable histamine H3 receptor antagonists with robust wake-promoting activityDandu, Reddeppa reddy / Gruner, John A. / Mathiasen, Joanne R. et al. | 2011
- 6366
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Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinasesNishiguchi, Gisele A. / Atallah, Gordana / Bellamacina, Cornelia et al. | 2011
- 6370
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Synthesis of lipids for development of multifunctional lipid-based drug-carriersZhu, Guodong / Alhamhoom, Yahya / Cummings, Brian S. et al. | 2011
- 6376
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Synthesis, iron(III)-binding affinity and in vitro evaluation of 3-hydroxypyridin-4-one hexadentate ligands as potential antimicrobial agentsXu, Bo / Kong, Xiao-Le / Zhou, Tao et al. | 2011
- 6381
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Discovery of a novel series of cyclic urea as potent CCR5 antagonistsDuan, Maosheng / Kazmierski, Wieslaw M. / Tallant, Matt et al. | 2011
- 6386
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Antitumor dinuclear platinum(II) complexes derived from a novel chiral ligandGao, Chuanzhu / Xu, Gang / Gou, Shaohua et al. | 2011
- 6389
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Design, synthesis, and biological evaluation of benzodiazepine-based SUMO-specific protease 1 inhibitorsQiao, Zhitao / Wang, Weiwei / Wang, Lie et al. | 2011
- 6393
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Synthesis of novel N-(2-hydroxy-2-p-tolylethyl)-amide and N-(2-oxo-2-p-tolylethyl)-amide derivatives and their antidyslipidemic and antioxidant activityNarender, T. / Rajendar, K. / Sarkar, S. et al. | 2011
- 6398
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Micelles catalyzed chemoselective synthesis ‘in water’ and biological evaluation of oxygen containing hetero-1,4-naphthoquinones as potential antifungal agentsTandon, Vishnu K. / Maurya, Hardesh K. / Mishra, Nripendra N. et al. | 2011
- 6404
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Homo- and hetero-dimers of inactive organophosphorous group binding at dual sites of AChEZhao, Qianfei / Xie, Ruliang / Zhang, Tao et al. | 2011
- 6409
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Discovery of spiropiperidine-based potent and selective Orexin-2 receptor antagonistsFujimoto, Tatsuhiko / Tomata, Yoshihide / Kunitomo, Jun et al. | 2011
- 6414
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Discovery of potent, selective, orally active benzoxazepine-based Orexin-2 receptor antagonistsFujimoto, Tatsuhiko / Kunitomo, Jun / Tomata, Yoshihide et al. | 2011
- 6417
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Halogen substituents on the aromatic moiety of the tetracaine scaffold improve potency of cyclic nucleotide-gated channel blockKirk, Sarah R. / Andrade, Adriana L. / Melich, Kenneth et al. | 2011
- 6420
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Synthesis and biological evaluation of hydroxylated 3-phenylcoumarins as antioxidants and antiproliferative agentsYang, Jie / Liu, Guo-Yun / Dai, Fang et al. | 2011
- 6426
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Secoiridoid glucosides and related compounds from Syringa reticulata and their antioxidant activitiesBi, Xueyan / Li, Wei / Sasaki, Tatsunori et al. | 2011
- 6430
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Vitamin B6s inhibit oxidative stress caused by Alzheimer’s disease-related CuII-β-amyloid complexes—cooperative action of phospho-moietyHashim, Alaa / Wang, Le / Juneja, Kashmir et al. | 2011
- 6430
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Vitamin B6s inhibit oxidative stress caused by Alzheimer's disease-related CuII-b-amyloid complexes-cooperative action of phospho-moietyHashim, A. / Wang, L. / Juneja, K. et al. | 2011
- 6433
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A Pd-mediated new strategy to functionalized 2-aminochromenes: Their in vitro evaluation as potential anti tuberculosis agentsRam Reddy, T. / Srinivasula Reddy, L. / Rajeshwar Reddy, G. et al. | 2011
- 6440
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Potent and selective 2-naphthylsulfonamide substituted hydroxamic acid inhibitors of matrix metalloproteinase-13Tommasi, Ruben A. / Weiler, Sven / McQuire, Leslie W. et al. | 2011
- 6446
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Radiolabeling of folic acid-modified chitosan with 99mTc as potential agents for folate-receptor-mediated targetingGuo, Wenyan / Jing, Huihui / Yang, Wenjiang et al. | 2011
- 6451
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Development of a highly selective, orally bioavailable and CNS penetrant M1 agonist derived from the MLPCN probe ML071Lebois, Evan P. / Digby, Gregory J. / Sheffler, Douglas J. et al. | 2011
- 6456
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Discovery of pyrazoles as novel FPR1 antagonistsMorley, Andrew D. / Cook, Andrew / King, Sarah et al. | 2011
- 6461
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Combining symmetry elements results in potent naphthyridinone (NTD) HIV-1 integrase inhibitorsJohns, Brian A. / Kawasuji, Takashi / Weatherhead, Jason G. et al. | 2011
- 6465
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3-Aminopyrrolidine-4-carboxylic acid as versatile handle for internal labeling of pyrrolidinyl PNAReenabthue, Nisanath / Boonlua, Chalothorn / Vilaivan, Chotima et al. | 2011
- 6470
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Discovery of novel pyridyl carboxamides as potent CCR5 antagonists and optimization of their pharmacokinetic profile in ratsDuan, Maosheng / Kazmierski, Wieslaw M. / Chong, Pek Y. et al. | 2011
- 6476
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Synthesis and 2D QSAR of O-sulphonated β-aminols derivatives as novel antifungal and antibacterial agentsSharma, Sugandha / Pandey, Atindra K. / Shukla, Praveen K. et al. | 2011
- 6476
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Synthesis and 2D QSAR of O-sulphonated b-aminols derivatives as novel antifungal and antibacterial agentsSharma, S. / Pandey, A. K. / Shukla, P. K. et al. | 2011
- 6482
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Protective effects of amentoflavone on Lamin A-dependent UVB-induced nuclear aberration in normal human fibroblastsPark, Nok-Hyun / Lee, Chan-Woo / Bae, Ji-hyun et al. | 2011
- 6485
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Discovery of novel Cobactin-T based matrix metalloproteinase inhibitors via a ring closing metathesis strategyWilson, Lawrence J. / Wang, Bingbing / Yang, Shyh-Ming et al. | 2011
- 6491
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Selectivity of 3prime-O-methylponkoranol for inhibition of N- and C-terminal maltase glucoamylase and sucrase isomaltase, potential therapeutics for digestive disorders or their sequelaeEskandari, R. / Jones, K. / Rose, D. R. et al. | 2011
- 6491
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Selectivity of 3′-O-methylponkoranol for inhibition of N- and C-terminal maltase glucoamylase and sucrase isomaltase, potential therapeutics for digestive disorders or their sequelaeEskandari, Razieh / Jones, Kyra / Rose, David R. et al. | 2011
- 6495
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Inhibition of c-Kit, VEGFR-2 (KDR), and ABCG2 by analogues of OSI-930Patel, Jay P. / Kuang, Ye-Hong / Chen, Zhe-Sheng et al. | 2011
- 6500
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5-(2prime-Pyridyl)-2-aminothiazoles: Alkyl amino sulfonamides and sulfamides as potent NPY5 antagonistsPackiarajan, M. / Coate, H. / Desai, M. et al. | 2011
- 6500
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5-(2′-Pyridyl)-2-aminothiazoles: Alkyl amino sulfonamides and sulfamides as potent NPY5 antagonistsPackiarajan, Mathivanan / Coate, Heather / Desai, Mahesh et al. | 2011
- 6505
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Conversion of systemically-distributed triazole-based stearoyl-CoA desaturase (SCD) uHTS hits into liver-targeted SCD inhibitorsLeclerc, Jean-Philippe / Falgueyret, Jean-Pierre / Girardin, Mélina et al. | 2011
- 6510
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Iodine-catalyzed conjugate addition of indoles onto en-1,4-dione: A novel synthesis of 3-(1-(1H-indol-3-yl)-2-oxo-2-phenylethyl)indolin-2-ones as antibacterial and antifungal agentsReddy, B.V. Subba / Rajeswari, N. / Sarangapani, M. et al. | 2011
- 6515
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Acidic triazoles as soluble guanylate cyclase stimulatorsRoberts, Lee R. / Bradley, Paul A. / Bunnage, Mark E. et al. | 2011
- 6519
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A dual fluorinated and iodinated radiotracer for PET and SPECT imaging of β-amyloid plaques in the brainWatanabe, Hiroyuki / Ono, Masahiro / Kimura, Hiroyuki et al. | 2011
- 6519
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A dual fluorinated and iodinated radiotracer for PET and SPECT imaging of b-amyloid plaques in the brainWatanabe, H. / Ono, M. / Kimura, H. et al. | 2011
- 6523
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Synthesis and preliminary biological evaluation of novel N-(3-aryl-1,2,4-triazol-5-yl) cinnamamide derivatives as potential antimycobacterial agents: An operational Topliss Tree approachKakwani, Manoj D. / Palsule Desai, Nutan H. / Lele, Arundhati C. et al. | 2011
- 6527
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Synthesis and anti-inflammatory activity of some new 4,5-dihydro-1,5-diaryl-1H-pyrazole-3-substituted-heteroazole derivativesDekhane, Deepak V. / Pawar, Shivaji S. / Gupta, Sunil et al. | 2011
- 6533
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Chemical scaffolds with structural similarities to siderophores of nonribosomal peptide–polyketide origin as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestisFerreras, Julian A. / Gupta, Akash / Amin, Neal D. et al. | 2011
- 6538
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Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 1: Identification of 7-azaspiro[3.5]nonane and 1-oxa-8-azaspiro[4.5]decane as lead scaffoldsMeyers, Marvin J. / Long, Scott A. / Pelc, Matthew J. et al. | 2011
- 6545
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Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 2. Discovery of 7-azaspiro[3.5]nonane urea PF-04862853, an orally efficacious inhibitor of fatty acid amide hydrolase (FAAH) for painMeyers, Marvin J. / Long, Scott A. / Pelc, Matthew J. et al. | 2011
- 6554
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Aminothiazoles as γ-secretase modulatorsLübbers, Thomas / Flohr, Alexander / Jolidon, Synese et al. | 2011
- 6554
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Aminothiazoles as g-secretase modulatorsLubbers, T. / Flohr, A. / Jolidon, S. et al. | 2011
- 6559
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Synthesis and biological evaluation of some novel triazol-3-ones as antimicrobial agentsPardeshi, Santosh / Bobade, Vivek D. et al. | 2011
- 6563
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Synthesis and in vitro evaluation of 7-methoxy-N-(pent-4-enyl)-1,2,3,4-tetrahydroacridin-9-amine—new tacrine derivate with cholinergic propertiesKorabecny, Jan / Musilek, Kamil / Zemek, Filip et al. | 2011
- 6567
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New PDE4 inhibitors based on pharmacophoric similarity between papaverine and tofisopamBihel, Frédéric J.J. / Justiniano, Hélène / Schmitt, Martine et al. | 2011
- 6573
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Novel 1-alkynyl substituted 1,2-dihydroquinoline derivatives from nimesulide (and their 2-oxo analogues): A new strategy to identify inhibitors of PDE4BPal, Sarbani / Durgadas, Shylaprasad / Nallapati, Suresh Babu et al. | 2011
- 6577
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Tricyclic aminopyrimidine histamine H4 receptor antagonistsSavall, Brad M. / Gomez, Laurent / Chavez, Frank et al. | 2011
- 6582
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Discovery of a novel potent GABAB receptor agonistXu, Feng / Peng, Ge / Phan, Thu et al. | 2011
- 6586
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Fragment based discovery of a novel and selective PI3 kinase inhibitorHughes, Samantha J. / Millan, David S. / Kilty, Iain C. et al. | 2011
- 6591
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Discovery of a series of potent and selective human H4 antagonists using ligand efficiency and libraries to explore structure–activity relationship (SAR)Masood, M. Abid / Selby, Matthew D. / Bell, Andrew S. et al. | 2011
- 6596
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Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: A novel histamine H4 receptor antagonistMowbray, Charles E. / Bell, Andrew S. / Clarke, Nicholas P. et al. | 2011
- 6603
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Selective cholinesterase inhibition by lanostane triterpenes from fruiting bodies of Ganoderma lucidumLee, IkSoo / Ahn, BoRa / Choi, JaeSue et al. | 2011
- 6608
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Discovery and optimization of a biphenylacetic acid series of prostaglandin D2 receptor DP2 antagonists with efficacy in a murine model of allergic rhinitisScott, Jill M. / Baccei, Christopher / Bain, Gretchen et al. | 2011
- 6613
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Erratum to “Identification of lysine acetyltransferase p300 substrates using 4-pentynoyl-coenzyme A and bioorthogonal proteomics” [Bioorg. Med. Chem. Lett. 21 (2011) 4976–4979]Yang, Yu-Ying / Grammel, Markus / Hang, Howard C. et al. | 2011
- IFC
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Editorial board| 2011