BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS
Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
Inhaltsverzeichnis
- 1465
-
Graphical contents list| 2010
- 1485
-
S1P receptor mediated activity of FTY720 phosphate mimicsHögenauer, Klemens / Hinterding, Klaus / Nussbaumer, Peter et al. | 2010
- 1488
-
Dioxo-triazines as a novel series of cathepsin K inhibitorsRankovic, Zoran / Cai, Jiaqiang / Fradera, Xavier et al. | 2010
- 1491
-
The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5Schiemann, Kai / Finsinger, Dirk / Zenke, Frank et al. | 2010
- 1496
-
Iodine scanning of a phenazine inhibitor of vacuolar sortingSurpin, Marci / Zou, Yunfan / Xiong, Chiyi et al. | 2010
- 1500
-
Design, synthesis, and evaluation of indole compounds as novel inhibitors targeting Gp41Zhou, Guangyan / Wu, Dong / Hermel, Evan et al. | 2010
- 1504
-
Antiproliferative activity of novel benzo[b][1,6]naphthyridines in human solid tumor cell linesRudys, Simonas / Ríos-Luci, Carla / Pérez-Roth, Eduardo et al. | 2010
- 1507
-
Effect of linker substitution on the binding of butorphan univalent and bivalent ligands to opioid receptorsFulton, Brian S. / Knapp, Brian L. / Bidlack, Jean M. et al. | 2010
- 1510
-
Derivatives of aryl amines containing the cytotoxic 1,4-dioxo-2-butenyl pharmacophoreJha, Amitabh / Mukherjee, Chandrani / Prasad, Ashok K. et al. | 2010
- 1516
-
Discovery of a novel series of potent S1P1 agonistsCrosignani, Stefano / Bombrun, Agnes / Covini, David et al. | 2010
- 1520
-
New anti-malarial phenylpropanoid conjugated iridoids from Morinda morindoidesTamura, Satoru / Kubata, Bruno Kilunga / Syamsurizal et al. | 2010
- 1524
-
Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitorsRankovic, Zoran / Cai, Jiaqiang / Kerr, Jennifer et al. | 2010
- 1528
-
Triterpene compounds isolated from Acer mandshuricum and their anti-inflammatory activityDing, Yan / Liang, Chun / Kim, Jun Ho et al. | 2010
- 1532
-
Synthesis of physostigmine analogues and evaluation of their anticholinesterase activitiesZhan, Zha-Jun / Bian, Hong-Ling / Wang, Jian-Wei et al. | 2010
- 1535
-
Absolute configurations of tubulin inhibitors taltobulin (HTI-286) and HTI-042 characterized by X-ray diffraction analysis and NMR studiesNiu, Chuansheng / Ho, Douglas M. / Zask, Arie et al. | 2010
- 1539
-
Novel pyrazolo-tetrahydropyridines as potent orexin receptor antagonistsSifferlen, Thierry / Boss, Christoph / Cottreel, Emmanuelle et al. | 2010
- 1543
-
Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding modeMeyers, Marvin J. / Pelc, Matthew / Kamtekar, Satwik et al. | 2010
- 1548
-
Carbonic anhydrase inhibitors. Inhibition of transmembrane isoforms IX, XII, and XIV with less investigated anions including trithiocarbonate and dithiocarbamateInnocenti, Alessio / Scozzafava, Andrea / Supuran, Claudiu T. et al. | 2010
- 1551
-
Azabicyclic sulfonamides as potent 11b-HSD1 inhibitorsShah, U. / Boyle, C. D. / Chackalamannil, S. et al. | 2010
- 1551
-
Azabicyclic sulfonamides as potent 11β-HSD1 inhibitorsShah, Unmesh / Boyle, Craig D. / Chackalamannil, Samuel et al. | 2010
- 1555
-
Structure–activity relationships of norepinephrine reuptake inhibitors with benzothiadiazine dioxide or dihydrosulfostyril coresFensome, Andrew / Goldberg, Joel / McComas, Casey C. et al. | 2010
- 1559
-
Azole-based inhibitors of AKT/PKB for the treatment of cancerZeng, Qingping / Allen, John G. / Bourbeau, Matthew P. et al. | 2010
- 1565
-
Radiosynthesis of novel carbon-11-labeled triaryl ligands for cannabinoid-type 2 receptorFujinaga, Masayuki / Kumata, Katsushi / Yanamoto, Kazuhiko et al. | 2010
- 1569
-
C-Aryl glycoside inhibitors of SGLT2: Exploration of sugar modifications including C-5 spirocyclizationRobinson, Ralph P. / Mascitti, Vincent / Boustany-Kari, Carine M. et al. | 2010
- 1573
-
Discovery and initial SAR of pyrimidin-4-yl-1H-imidazole derivatives with antiproliferative activity against melanoma cell linesLee, Junghun / Kim, Hwan / Yu, Hana et al. | 2010
- 1578
-
Biochemical analysis of cellular target of S-trityl-l-cysteine derivatives using affinity matrixShimizu, Makiko / Ishii, Hirosuke / Ogo, Naohisa et al. | 2010
- 1581
-
Acidic elements in histamine H3 receptor antagonistsSander, Kerstin / von Coburg, Yvonne / Camelin, Jean-Claude et al. | 2010
- 1585
-
N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptaseMitchell, Michael L. / Son, Jong Chan / Lee, Ill Young et al. | 2010
- 1589
-
N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptaseMitchell, Michael L. / Son, Jong Chan / Guo, Hongyan et al. | 2010
- 1593
-
SAR and optimization of thiazole analogs as potent stearoyl-CoA desaturase inhibitorsRamtohul, Yeeman K. / Black, Cameron / Chan, Chi-Chung et al. | 2010
- 1598
-
Tellimagrandin I, HCV invasion inhibitor from Rosae Rugosae FlosTamura, Satoru / Yang, Gang-Ming / Yasueda, Natsuko et al. | 2010
- 1601
-
Synthesis and evaluation of opioid receptor-binding affinity of elaeocarpenine and its analogsKurasaki, Haruaki / Okamoto, Iwao / Morita, Nobuyoshi et al. | 2010
- 1604
-
Selective inducible microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from an oxicam templateWang, Jane / Limburg, David / Carter, Jeff et al. | 2010
- 1610
-
Novel multiple opioid ligands based on 4-aminobenzazepinone (Aba), azepinoindole (Aia) and tetrahydroisoquinoline (Tic) scaffoldsBallet, Steven / Marczak, Ewa D. / Feytens, Debby et al. | 2010
- 1614
-
Design, synthesis and biological evaluation of estradiol–chlorambucil hybrids as anticancer agentsGupta, Atul / Saha, Pijus / Descôteaux, Caroline et al. | 2010
- 1619
-
Metabolic activation of N-thiazol-2-yl benzamide as glucokinase activators: Impacts of glutathione trapping on covalent bindingIino, Tomoharu / Hashimoto, Noriaki / Hasegawa, Takuro et al. | 2010
- 1623
-
Novel molecular hybrids of cinnamic acids and guanylhydrazones as potential antitubercular agentsBairwa, Ranjeet / Kakwani, Manoj / Tawari, Nilesh R. et al. | 2010
- 1626
-
Effect of 3prime-end capping of aptamer with various 2prime,4prime-bridged nucleotides: Enzymatic post-modification toward a practical use of polyclonal aptamersKasahara, Y. / Kitadume, S. / Morihiro, K. et al. | 2010
- 1626
-
Effect of 3′-end capping of aptamer with various 2′,4′-bridged nucleotides: Enzymatic post-modification toward a practical use of polyclonal aptamersKasahara, Yuuya / Kitadume, Shunsuke / Morihiro, Kunihiko et al. | 2010
- 1630
-
Novel 6-N-arylcarboxamidopyrazolo[4,3-d]pyrimidin-7-one derivatives as potential anti-cancer agentsDevegowda, Vani N. / Kim, Jung Hyun / Han, Ki-Cheol et al. | 2010
- 1634
-
Discovery of potent and selective bicyclic A2B adenosine receptor antagonists via bioisosteric amide replacementEastwood, Paul / Gonzalez, Jacob / Paredes, Sergio et al. | 2010
- 1638
-
Exploration of SAR features by modifications of thiazoleacetic acids as CRTH2 antagonistsGrimstrup, Marie / Receveur, Jean-Marie / Rist, Øystein et al. | 2010
- 1642
-
Stereospecific synthesis of oximes and oxime ethers of 3-azabicycles: A SAR study towards antimicrobial agentsParthiban, Paramasivam / Rathika, Paramasivam / Ramkumar, Venkatachalam et al. | 2010
- 1648
-
The role of phosphate in the action of thymidine phosphorylase inhibitors: Implications for the catalytic mechanismJain, Harsh V. / Rasheed, Roshni / Kalman, Thomas I. et al. | 2010
- 1652
-
2-Aminothiadiazole inhibitors of AKT1 as potential cancer therapeuticsZeng, Qingping / Bourbeau, Matthew P. / Wohlhieter, G. Erich et al. | 2010
- 1657
-
3-(Arylsulfonyl)-1-(azacyclyl)-1H-indoles are 5-HT6 receptor modulatorsBernotas, Ronald C. / Antane, Schuyler / Shenoy, Rajesh et al. | 2010
- 1661
-
3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3βArnost, Michael / Pierce, Al / Haar, Ernst ter et al. | 2010
- 1661
-
3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3bArnost, M. / Pierce, A. / Haar, E. t. et al. | 2010
- 1665
-
Synthetic atpenin analogs: Potent mitochondrial inhibitors of mammalian and fungal succinate-ubiquinone oxidoreductaseSelby, Thomas P. / Hughes, Kenneth A. / Rauh, James J. et al. | 2010
- 1669
-
Replacement of pyrazol-3-yl amine hinge binder with thiazol-2-yl amine: Discovery of potent and selective JAK2 inhibitorsIoannidis, Stephanos / Lamb, Michelle L. / Almeida, Lynsie et al. | 2010
- 1674
-
Evaluation of a 3-amino-8-azabicyclo[3.2.1]octane replacement in the CCR5 antagonist maravirocLemoine, Rémy C. / Petersen, Ann C. / Setti, Lina et al. | 2010
- 1677
-
2-Anilino-4-aryl-1,3-thiazole inhibitors of valosin-containing protein (VCP or p97)Bursavich, Matthew G. / Parker, Daniel P. / Willardsen, J. Adam et al. | 2010
- 1680
-
Part 2: Structure–activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38α mitogen-activated protein kinaseWurz, Ryan P. / Pettus, Liping H. / Henkle, Bradley et al. | 2010
- 1680
-
Part 2: Structure-activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38a mitogen-activated protein kinaseWurz, R. P. / Pettus, L. H. / Henkle, B. et al. | 2010
- 1685
-
Semi-automated high-throughput fluorescent intercalator displacement-based discovery of cytotoxic DNA binding agents from a large compound libraryGlass, LaTeca S. / Bapat, Aditi / Kelley, Mark R. et al. | 2010
- 1689
-
Towards the second generation of Boceprevir: Dithianes as an alternative P2 substituent for 2,2-dimethyl cycloproyl proline in HCV NS3 protease inhibitorsNair, Latha G. / Bogen, Stephane / Ruan, Sumei et al. | 2010
- 1693
-
Discovery of potent and bioavailable GSK-3b inhibitorsGong, L. / Hirschfeld, D. / Tan, Y. C. et al. | 2010
- 1693
-
Discovery of potent and bioavailable GSK-3β inhibitorsGong, Leyi / Hirschfeld, Don / Tan, Yun-Chou et al. | 2010
- 1697
-
Discovery of N-(5,6-diarylpyridin-2-yl)amide derivatives as potent and selective A2B adenosine receptor antagonistsEastwood, Paul / Gonzalez, Jacob / Paredes, Sergio et al. | 2010
- 1701
-
Carbonic anhydrase activators: Activation of the β-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acidsInnocenti, Alessio / Leewattanapasuk, Worraanong / Manole, Gheorghe et al. | 2010
- 1701
-
Carbonic anhydrase activators: Activation of the b-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acidsInnocenti, A. / Leewattanapasuk, W. / Manole, G. et al. | 2010
- 1705
-
Arylpiperazine-containing pyrrole 3-carboxamide derivatives targeting serotonin 5-HT2A, 5-HT2C, and the serotonin transporter as a potential antidepressantKang, Suk Youn / Park, Eun-Jung / Park, Woo-Kyu et al. | 2010
- 1712
-
LXXLL peptide mimetics as inhibitors of the interaction of vitamin D receptor with coactivatorsMita, Yusuke / Dodo, Kosuke / Noguchi-Yachide, Tomomi et al. | 2010
- 1718
-
Design, synthesis, evaluation and QSAR analysis of N1-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitorsTakahashi, Jun / Hijikuro, Ichiro / Kihara, Takeshi et al. | 2010
- 1721
-
Design, synthesis and evaluation of carbamate-modified (−)-N1-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitorsTakahashi, Jun / Hijikuro, Ichiro / Kihara, Takeshi et al. | 2010
- 1724
-
2-Amino-aryl-7-aryl-benzoxazoles as potent, selective and orally available JAK2 inhibitorsGerspacher, Marc / Furet, Pascal / Pissot-Soldermann, Carole et al. | 2010
- 1728
-
Decahydroisoquinoline derivatives as novel non-peptidic, potent and subtype-selective somatostatin sst3 receptor antagonistsTroxler, Thomas / Hurth, Konstanze / Schuh, Karl-Heinrich et al. | 2010
- 1735
-
Exploration of a new series of PAR1 antagonistsPlanty, Bruno / Pujol, Chantal / Lamothe, Marie et al. | 2010
- 1740
-
Novel tetrahydrochinoline derived CETP inhibitorsSchmeck, Carsten / Gielen-Haertwig, Heike / Vakalopoulos, Alexandros et al. | 2010
- 1744
-
SAR of PXR transactivation in benzimidazole-based IGF-1R kinase inhibitorsZimmermann, Kurt / Wittman, Mark D. / Saulnier, Mark G. et al. | 2010
- 1749
-
Synthesis and in vitro evaluation of 18F-labelled S-fluoroalkyl diarylguanidines: Novel high-affinity NMDA receptor antagonists for imaging with PETRobins, Edward G. / Zhao, Yongjun / Khan, Imtiaz et al. | 2010
- 1752
-
Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB1 receptor antagonistsLange, Jos H.M. / van der Neut, Martina A.W. / den Hartog, Arnold P. et al. | 2010
- 1758
-
Identification of piperazine-bisamide GHSR antagonists for the treatment of obesityYu, Ming / Lizarzaburu, Mike / Beckmann, Holger et al. | 2010
- 1763
-
Preparation and in vitro screening of symmetrical bispyridinium cholinesterase inhibitors bearing different connecting linkage—initial study for Myasthenia gravis implicationsMusilek, Kamil / Komloova, Marketa / Zavadova, Vlasta et al. | 2010
- 1767
-
Development of improved inhibitors of wall teichoic acid biosynthesis with potent activity against Staphylococcus aureusLee, Kyungae / Campbell, Jennifer / Swoboda, Jonathan G. et al. | 2010
- 1771
-
Structure–activity relationships of bacterial outer-membrane permeabilizers based on polymyxin B heptapeptidesUrakawa, Hirotoshi / Yamada, Keiichi / Komagoe, Keiko et al. | 2010
- 1776
-
Selection of inhibitory peptides for Aurora-A kinase from a phage-displayed library of helix–loop–helix peptidesFujiwara, Daisuke / Ye, Zhengmao / Gouda, Masaki et al. | 2010
- 1779
-
Rapid P1 SAR of brain penetrant tertiary carbinamine derived BACE inhibitorsZhu, Hong / Young, Mary B. / Nantermet, Philippe G. et al. | 2010
- 1783
-
Orally bioavailable anti-HBV dinucleotide acyloxyalkyl prodrugsCoughlin, John E. / Padmanabhan, Seetharamaiyer / Zhang, Guangrong et al. | 2010
- 1787
-
Podophyllotoxin analogues active versus Trypanosoma bruceiUddin, Md. Jashim / Smithson, David C. / Brown, Kristin M. et al. | 2010
- 1792
-
Use of polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline for the preparation of a hapten–protein conjugate for antibody developmentSathe, Manisha / Derveni, Mariliza / Allen, Marjorie et al. | 2009
- 1796
-
Corrigendum to “Pyridine containing M1 positive allosteric modulators with reduced plasma protein binding” [Bioorg. Med. Chem. Lett. 20 (2010) 657]Kuduk, Scott D. / Di Marco, Christina N. / Cofre, Victoria et al. | 2010
- 1797
-
Corrigendum to “Discovery of novel taspine derivatives as antiangiogenic agents” [Bioorg. Med. Chem. Lett. 20 (2010) 718]Zhang, Jie / Zhang, Yanmin / Zhang, Sanqi et al. | 2010
- 1798
-
Corrigendum to “Development of photoaffinity probes for γ-secretase equipped with a nitrobenzenesulfonamide-type cleavable linker” [Bioorg. Med. Chem. Lett. 19 (2009) 6869]Yokoshima, Satoshi / Abe, Yuzo / Watanabe, Naoto et al. | 2010
- 1798
-
Corrigendum to "Development of photoaffinity probes for g-secretase equipped with a nitrobenzenesulfonamide-type cleavable linker" [Bioorg. Med. Chem. Lett. 19 (2009) 6869]Yokoshima, S. / Abe, Y. / Watanabe, N. et al. | 2010
- 1800
-
Corrigendum to “Discovery and SAR of cyclic isothioureas as novel NPY Y1 receptor antagonists” [Bioorg. Med. Chem. Lett. 19 (2009) 6801]Sun, Zhong-Yue / Zhu, Zhaoning / Ye, Yuanzan et al. | 2010
- IFC
-
Editorial board| 2010