Organic Process Research & Development
Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
Inhaltsverzeichnis
- 297
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Could This Happen in Your Company?Laird, Trevor et al. | 2007
- 299
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Some Items of Interest to Process R&D Chemists and EngineersMcLaughlin, Mark / García Rubio, Silvina / Tilstam, Ulf et al. | 2007
- 311
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Regulatory Highlights for 2006 to March 2007Robinson, Derek et al. | 2007
- 318
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A Review of U.S. Patents in the Field of Organic Process Development Published during October to December 2006Turner, Keith et al. | 2007
- 328
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From High-Throughput Catalyst Screening to Reaction Optimization: Detailed Investigation of Regioselective Suzuki Coupling of 1,6-Naphthyridone DichlorideCai, Chaoxian / Chung, John Y. L. / McWilliams, J. Christopher et al. | 2007
- 336
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An Improved Manufacturing Process for the Antimalaria Drug Coartem. Part IBoehm, Matthias / Fuenfschilling, Peter C. / Krieger, Matthias et al. | 2007
- 341
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An Improved Manufacturing Process for the Antimalaria Drug Coartem. Part IIBeutler, Ulrich / Fuenfschilling, Peter C. / Steinkemper, Andreas et al. | 2007
- 346
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Process Development and Scale-up for (±)-Reboxetine MesylateHenegar, Kevin E. / Ball, Cynthia T. / Horvath, Carolyn M. et al. | 2007
- 354
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Process Development for (S,S)-Reboxetine Succinate via a Sharpless Asymmetric EpoxidationHenegar, Kevin E. / Cebula, Mateusz et al. | 2007
- 359
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Suppression of a Palladium-Mediated Homocoupling in a Suzuki Cross-Coupling Reaction. Development of an Impurity Control Strategy Supporting Synthesis of LY451395Miller, William D. / Fray, Andrew H. / Quatroche, John T. et al. | 2007
- 365
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An Approach to Early-Phase Salt Selection: Application to NBI-75043Gross, Timothy D. / Schaab, Kevin / Ouellette, Michael et al. | 2007
- 378
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Development of a Commercial Process to Produce OxandroloneCabaj, John E. / Kairys, David / Benson, Thomas R. et al. | 2007
- 389
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Practical Synthesis and Molecular Structure of a Potent Broad-Spectrum Antibacterial IsothiazoloquinoloneHashimoto, Akihiro / Pais, Godwin C. G. / Wang, Qiuping et al. | 2007
- 399
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A Microcapillary Flow Disc Reactor for Organic SynthesisHornung, Christian H. / Mackley, Malcolm R. / Baxendale, Ian R. et al. | 2007
- 406
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Highly Functionalised Sulfur-Based Silica Scavengers for the Efficient Removal of Palladium Species from Active Pharmaceutical IngredientsGalaffu, Nicola / Man, Siud Pui / Wilkes, Robin D. et al. | 2007
- 414
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Synthesis of Tetracyclic Heterocompounds as Selective Estrogen Receptor Modulators. Part 1. Process Development for Scale-up of 2,5,8-Substituted 5,11-Dihydrochromeno[4,3-c]chromene DerivativesLi, Xun / Reuman, Michael / Russell, Ronald K. et al. | 2007
- 422
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Scale-Up Syntheses of Two Naturally Occurring Procyanidins: (-)-Epicatechin-(4&bgr;,8)-(+)-catechin and (-)-Epicatechin-3-O-galloyl-(4&bgr;,8)-(-)-epicatechin-3-O-gallateF- NR RID="op700031nAF2" SSYMBOL="dagger">Sharma, P.K. et al. | 2007
- 422
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Scale-Up Syntheses of Two Naturally Occurring Procyanidins: (−)-Epicatechin-(4β,8)-(+)-catechin and (−)-Epicatechin-3-O-galloyl-(4β,8)-(−)-epicatechin-3-O-gallate †Sharma, Pradeep K. / Kolchinski, Alexander / Shea, Hélène A. et al. | 2007
- 422
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Scale-Up Syntheses of Two Naturally Occurring Procyanidins: (-)-Epicatechin-(4beta,8)-(+)-catechin and (-)-Epicatechin-3-O-galloyl-(4beta,8)-(-)-epicatechin-3-O-gallateSharma, P. K. / Kolchinski, A. / Shea, H. A. et al. | 2007
- 431
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A Convergent Kilogram-Scale Synthesis of the PPARα Agonist LY518674: Discovery of a Novel Acid-Mediated Triazolone SynthesisBraden, Timothy M. / Coffey, D. Scott / Doecke, Christopher W. et al. | 2007
- 431
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A Convergent Kilogram-Scale Synthesis of the PPARalpha Agonist LY518674: Discovery of a Novel Acid-Mediated Triazolone SynthesisBraden, T. M. / Coffey, D. S. / Doecke, C. W. et al. | 2007
- 441
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The Preparation of Two, Preclinical Amino-quinazolinediones as Antibacterial AgentsBeylin, Vladimir / Boyles, David C. / Curran, Timothy T. et al. | 2007
- 450
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An Efficient Synthesis of Dibenzo[c,f]-2,7-naphthyridine Ring System through Design of ExperimentsGopalsamy, Ariamala / Shi, Mengxiao / Nilakantan, Ramaswamy et al. | 2007
- 455
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An Alternative Approach to Achieve Enantiopure (3S)-4-Benzyl-3- (4-fluorophenyl)morpholin-2-one: A Key Intermediate of Aprepitant, an NK1 Receptor Antagonist †Kolla, Naveenkumar / Elati, Chandrashekar R. / Arunagiri, Muthulingam et al. | 2007
- 455
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An Alternative Approach to Achieve Enantiopure (3S)-4-Benzyl-3- (4-fluorophenyl)morpholin-2-one: A Key Intermediate of Aprepitant, an NK1 Receptor AntagonistFNR RID="op700030dAF2" SSYMBOL="dagger">Kolla, N. et al. | 2007
- 458
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Continuous Flow Ligand-Free Heck Reactions Using Monolithic Pd [0] NanoparticlesNikbin, Nikzad / Ladlow, Mark / Ley, Steven V. et al. | 2007
- 463
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Improved and Practical Synthesis of 6-Methoxy-1,2,3,4- tetrahydroisoquinoline HydrochlorideZhong, H. Marlon / Villani, Frank J. / Marzouq, Ramzy et al. | 2007
- 466
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An Improved Process for the Preparation of 4,4-Dimethyloxazolidine-2-thioneTewari, Neera / Nair, Dinesh / Nizar, Hashim et al. | 2007
- 468
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A Facile Process for the Preparation of 2-Bromoethyl Methyl EtherDasari, Varaprasad / Srinivas, Rao V. / Akula, Kalyan Chakravarthy et al. | 2007
- 470
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A Green Chemistry Comparative Analysis of the Syntheses of (E)-4-Cyclobutyl-2-[2-(3-nitrophenyl)ethenyl] Thiazole, Ro 24-5904Kuzemko, Michael A. / Van Arnum, Susan D. / Niemczyk, Henry J. et al. | 2007
- 477
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QuadraPure Cartridges for Removal of Trace Metal from Reaction Mixtures in FlowHinchcliffe, A. / Hughes, C. / Pears, D. A. et al. | 2007
- 482
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High-Yielding Syntheses of 1-Piperidin-4-yl Butyro- and Valerolactams through a Tandem Reductive Amination−Lactamization (Reductive Lactamization)Mapes, Christopher M. / Mani, Neelakandha S. et al. | 2007
- 487
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Synthetic Improvements in the Preparation of ClopidogrelWang, Lixin / Shen, Jianfen / Tang, Yi et al. | 2007
- 490
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New Practical Synthesis of the Key Intermediate of CandesartanPorcs-Makkay, Márta / Mezei, Tibor / Simig, Gyula et al. | 2007
- 494
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SPECIAL FEATURE SECTION: ASYMMETRIC SYNTHESIS ON LARGE SCALEFedersel, Hans Jürgen / Brands, Karel M. J. et al. | 2007
- 495
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Catalytic Asymmetric Carbon−Carbon Bond Formations: Their Evolution from Biocatalysis to Organocatalysis over the MillenniumIkunaka, Masaya et al. | 2007
- 503
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Bioreactor Systems for the Production of Optically Active Amino Acids and AlcoholsNanba, Hirokazu / Yasohara, Yoshihiko / Hasegawa, Junzo et al. | 2007
- 509
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Practical Copper-Catalyzed Asymmetric Synthesis of Chiral Chrysanthemic Acid EstersItagaki, Makoto / Suenobu, Katsuhiro et al. | 2007
- 519
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Enantioselective Ketone Hydrogenation: From R&D to Pilot Scale with Industrially Viable Ru/Phosphine−Oxazoline ComplexesNaud, Frédéric / Spindler, Felix / Rueggeberg, Carsten J. et al. | 2007
- 524
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Enantioselective Synthesis of a Key Intermediate in a New Process for Orlistat Using Asymmetric Hydrogenation and a Grignard Reagent Promoted Lactone CyclizationSchwindt, Mark A. / Fleming, Michael P. / Han, Yeun-Kwei et al. | 2007
- 534
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Development of an Asymmetric Acetate Aldol Reaction with a Trifluoromethyl KetoneSong, Jinhua J. / Xu, Jinghua / Tan, Zhulin et al. | 2007
- 539
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Efficient Asymmetric Synthesis of N-[(1R)-6-Chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl]-2-pyridinecarboxamide for Treatment of Human Papillomavirus InfectionsBoggs, Sharon D. / Cobb, Jeremy D. / Gudmundsson, Kristjan S. et al. | 2007
- 546
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Design, Development, and Scale-Up of a Selective meso-Epoxide Desymmetrization ProcessVarie, David L. / Beck, Christopher / Borders, Sandra K. et al. | 2007
- 560
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Optimized Catalytic Enantioselective Aryl Transfer Process Gives Access to mGlu2 Receptor PotentiatorsMagnus, Nicholas A. / Anzeveno, Peter B. / Coffey, D. Scott et al. | 2007
- 568
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Development of Practical Rhodium Phosphine Catalysts for the Hydrogenation of beta-Dehydroamino Acid DerivativesEnthaler, S. / Erre, G. / Junge, K. et al. | 2007
- 568
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Development of Practical Rhodium Phosphine Catalysts for the Hydrogenation of β-Dehydroamino Acid DerivativesEnthaler, Stephan / Erre, Giulia / Junge, Kathrin et al. | 2007
- 578
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Development of a Large Scale Asymmetric Synthesis of Vanilloid Receptor (TRPV1) Antagonist ABT-102Lukin, Kirill / Hsu, Margaret C. / Chambournier, Gilles et al. | 2007
- 585
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A Mixed-Ligand Approach Enables the Asymmetric Hydrogenation of an α-Isopropylcinnamic Acid en Route to the Renin Inhibitor AliskirenBoogers, Jeroen A. F. / Felfer, Ulfried / Kotthaus, Martina et al. | 2007
- 585
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A Mixed-Ligand Approach Enables the Asymmetric Hydrogenation of an alpha-Isopropylcinnamic Acid en Route to the Renin Inhibitor AliskirenBoogers, J. A. F. / Felfer, U. / Kotthaus, M. et al. | 2007
- 592
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Solvent-Free Asymmetric Anhydride Opening in a Ball MillRantanen, Toni / Schiffers, Ingo / Bolm, Carsten et al. | 2007
- 598
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Enantioselective Synthesis of Hydrobenzofuranones Using an Asymmetric Desymmetrizing Intramolecular Stetter Reaction of CyclohexadienonesLiu, Qin / Rovis, Tomislav et al. | 2007
- 605
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Development of a Preparative-Scale Asymmetric Synthesis of (R)-p-Tolyl Methyl Sulfoxide for Use in a One-Pot Synthesis of a Drug Intermediate Containing a Trifluoromethyl-Substituted Alcohol FunctionalityHan, Zhengxu / Song, Jinhua J. / Yee, Nathan K. et al. | 2007
- 609
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Practical Syntheses of Chiral α-Amino Acids and Chiral Half-Esters by Kinetic Resolution of Urethane-Protected α-Amino Acid N-Carboxyanhydrides and Desymmetrization of Cyclic meso-Anhydrides with New Modified Cinchona Alkaloid CatalystsIshii, Yutaka / Fujimoto, Ryosuke / Mikami, Masafumi et al. | 2007
- 609
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Practical Syntheses of Chiral alpha-Amino Acids and Chiral Half-Esters by Kinetic Resolution of Urethane-Protected alpha-Amino Acid N-Carboxyanhydrides and Desymmetrization of Cyclic meso-Anhydrides with New Modified Cinchona Alkaloid CatalystsIshii, Y. / Fujimoto, R. / Mikami, M. et al. | 2007
- 616
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Catalytic, Enantioselective Synthesis of Taranabant, a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist for the Treatment of ObesityChen, Cheng-yi / Frey, Lisa F. / Shultz, Scott et al. | 2007
- 624
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Synthesis of 4-Fluoro-β-(4-fluorophenyl)-l-phenylalanine by an Asymmetric Phase-Transfer Catalyzed Alkylation: Synthesis on Scale and Catalyst StabilityPatterson, Daniel E. / Xie, Shiping / Jones, Lynda A. et al. | 2007
- 624
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Synthesis of 4-Fluoro-beta-(4-fluorophenyl)-L-phenylalanine by an Asymmetric Phase-Transfer Catalyzed Alkylation: Synthesis on Scale and Catalyst StabilityPatterson, D. E. / Xie, S. / Jones, L. A. et al. | 2007
- 628
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Design of Chiral Phase Transfer Catalyst with Conformationally Fixed Biphenyl Core: Application to Asymmetric Alkylation of Glycine DerivativesWang, Yong-Gang / Maruoka, Keiji et al. | 2007
- 633
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Enantioselective Reduction of Nitroalkene Mixtures by in Situ EquilibrationCzekelius, Constantin / Carreira, Erick M. et al. | 2007
- 637
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A Practical and Scaleable Synthesis of 1R,5S-Bicyclo[3.1.0]hexan-2-one: The Development of a Catalytic Lithium 2,2,6,6-Tetramethylpiperidide (LTMP) Mediated Intramolecular Cyclopropanation of (R)-1,2-Epoxyhex-5-eneAlorati, Anthony D. / Bio, Matthew M. / Brands, Karel M. J. et al. | 2007
- 642
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Catalytic Racemisation of Chiral Amines and Application in Dynamic Kinetic ResolutionBlacker, A. John / Stirling, Matthew J. / Page, Michael I. et al. | 2007
- 649
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Fundamentals of Early Clinical Drug Development: From Synthesis Design to Formulation Edited by A. F. Abdel-Magid and S. Caron. Wiley: New Jersey. 2006. 323 pp. £58.95. ISBN 0-471-69278-6.| 2007
- 649
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Polymorphism in the Pharmaceutical Industry Edited by R. Hilfiker. Wiley-VCH: Weinheim. 2006. 414 + xix pp. £105. ISBN 3-527-31146-7.| 2007
- 650
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Handbook of Industrial Biocatalysis Edited by Ching T. Hou. CRC/Taylor & Francis: Boca Raton, FL. 2005. 557 pp + xv. $179.95. ISBN 0824724232.| 2007