Comparative RNA-seq analyses identify new microRNA biomarkers and candidate target genes in patients’ drug-resistant CD34+ CML stem/progenitor cells (Unbekannt)
- Neue Suche nach: Lin, Hanyang
- Neue Suche nach: Rothe, Katharina
- Neue Suche nach: Ruschmann, Jens
- Neue Suche nach: Petriv, Oleh
- Neue Suche nach: O'Neill, Kieran
- Neue Suche nach: Knapp, David
- Neue Suche nach: Brinkman, Ryan
- Neue Suche nach: Birol, Inanc
- Neue Suche nach: Forrest, Donna
- Neue Suche nach: Hansen, Carl
- Neue Suche nach: Eaves, Connie
- Neue Suche nach: Humphries, Keith
- Neue Suche nach: Jiang, Xiaoyan
- Neue Suche nach: Lin, Hanyang
- Neue Suche nach: Rothe, Katharina
- Neue Suche nach: Ruschmann, Jens
- Neue Suche nach: Petriv, Oleh
- Neue Suche nach: O'Neill, Kieran
- Neue Suche nach: Knapp, David
- Neue Suche nach: Brinkman, Ryan
- Neue Suche nach: Birol, Inanc
- Neue Suche nach: Forrest, Donna
- Neue Suche nach: Hansen, Carl
- Neue Suche nach: Eaves, Connie
- Neue Suche nach: Humphries, Keith
- Neue Suche nach: Jiang, Xiaoyan
In:
Experimental hematology
;
43
;
S63
;
2015
-
ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:Comparative RNA-seq analyses identify new microRNA biomarkers and candidate target genes in patients’ drug-resistant CD34+ CML stem/progenitor cells
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Beteiligte:Lin, Hanyang ( Autor:in ) / Rothe, Katharina ( Autor:in ) / Ruschmann, Jens ( Autor:in ) / Petriv, Oleh ( Autor:in ) / O'Neill, Kieran ( Autor:in ) / Knapp, David ( Autor:in ) / Brinkman, Ryan ( Autor:in ) / Birol, Inanc ( Autor:in ) / Forrest, Donna ( Autor:in ) / Hansen, Carl ( Autor:in )
-
Erschienen in:Experimental hematology ; 43 ; S63
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Verlag:
- Neue Suche nach: Elsevier Science B.V., Amsterdam.
-
Erscheinungsdatum:01.01.2015
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Format / Umfang:S63
-
ISSN:
-
Medientyp:Aufsatz (Zeitschrift)
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Format:Print
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Sprache:Unbekannt
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Datenquelle:
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- 1031
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- 1047
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- 1062
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- A3
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Contents| 2015
- e1
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ISEH Annual Meeting Late Breaking Abstracts| 2015
- e11
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ISEH Annual Meeting Abstract Changes| 2015
- S21
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Reprint to: In memoriam: Donald Metcalf (1929-2014) – A historical perspective of his contributions to hematologyNicola, Nicos A. / Alexander, Warren S. / Hilton, Douglas J. / Ng, Ashley P. et al. | 2015
- S107
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Author Index| 2015
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HSC transplantation in an immunocompetent host without radiation or chemotherapyChhabra, Akanksha / Ring, Aaron / Weiskopf, Kipp / Schnorr, Peter John / Gordon, Sydney / Le, Alan C. / Kwon, Hye-Sook / Guo, Nan / Volkmer, Jens / Ho, Po Yi et al. | 2015
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Declined presentation the role of c-Myc in regulating microenvironment for erythropoiesis and megkaryocytopoiesisHayashi, Yoshihiro / Wu, Lingyun / Huang, Gang et al. | 2015
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EZH2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an EZH1-depenedent mannerMochizuki-Kashio, Makiko / Sashida, Goro / Aoyama, Kazumasa / Wang, Changshan / Tomioka, Takahisa / Oshima, Motohiko / Iwama, Atsushi et al. | 2015
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-
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Optical techniques for characterizing the bone marrow microenvironmentLin, Charles P. et al. | 2015
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The role of Gata3 in blood stem cell emergenceZaidan, Nada M. / Fitch, Simon R. / Ottersbach, Katrin et al. | 2015
-
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-
Fanconi anemia pathway safeguards interphase and mitosis in vivoCerabona, Donna / Sater, Zahi A. / Potchanant, Elizabeth Sierra / Sun, Zejin / He, Ying / Nalepa, Grzegorz et al. | 2015
-
Declined presentation OP9-LHX2 stromal cells facilitate derivation of hematopoietic progenitors both in vitro and in vivoChen, Xiaoli / Zhao, Qianhao / Geng, Yang / Wang, Tongjie / Yang, Dan / Wang, Jinyong et al. | 2015
-
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Identification of Flt3-ligand producing cells by generating Flt3-ligand mcherry reporter mouseOnai, Nobuyuki / Kurosaki-Nakamura, Rumiko / Ohteki, Toshiaki et al. | 2015
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Table of Contents| 2015
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Oncogenic micrornas in cerberospinal fluid: Sensitive tool for detection of CNS lymphoma, estimation of therapy efficacy and prediction of CNS relapsePospisil, Vitek / Mocikova, Heidi / Trneny, Marek / Stopka, Tomas et al. | 2015
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Genome-wide RNA tomography analysis of the microenvironment promoting hematopoietic stem cell emergence in the embryo aortaYvernogeau, Laurent / Junker, Jan Philipp / van Oudenaarden, Alexander / Robin, Catherine et al. | 2015
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Conserved transcriptional programmes regulating blood cell developmentWilkinson, Adam C. / Tanaka, Yosuke / Wang, Wei / Ryan, David J. / Liu, Pentao / Gottgens, Bertie et al. | 2015
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Role of the polycomb gene BCOR in hematopoiesisTanaka, Tomoyuki / Nakajima-Takagi, Yeako / Oshima, Motohiko / Saraya, Atsunori / Tara, Shiro / Si, Sha / Sone, Hirohito / Koseki, Haruhiko / Iwama, Atsushi et al. | 2015
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Lyve1 marks yolk sac definitive hemogenic endotheliumLee, Lydia / Ghorbanian, Yasamine / Weissman, Irving / Inlay, Matthew / Mikkola, Hanna et al. | 2015
-
The zebrafish homologue of the murine EVI1 gene critically regulates hsc developmentKonantz, Martina / Müller, Joëlle / Lenard, Anna / Esain, Virginie / North, Trista E. / Lengerke, Claudia et al. | 2015
-
Leukemic mesenchymal stem cells impedes the generation of normal hematopoietic progenitor cellsLim, Meikuang / Pang, Yakun / Ma, Shihui / Hao, Sha / Shi, Hui / Zheng, Yawei / Hua, Chunlan / Yang, Fengchun / Yuan, Weiping / Cheng, Tao et al. | 2015
-
Evaluation of stem cell characteristics of adult mouse bone-derived small cellsNakatsuka, Ryusuke / Matsuoka, Yoshikazu / Sumide, Keisuke / Kawamura, Hiroshi / Fujioka, Tatsuya / Sasaki, Yutaka / Sonoda, Yoshiaki et al. | 2015
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Identification of ATL stem cells in an ATL model HBZ transgenic mouseKuribayashi, Wakako / Mizukami, Takuo / Takizawa, Kazuya / Sugata, Kenji / Kuramitsu, Madoka / Momose, Haruka / Iwama, Atsushi / Hamaguchi, Isao et al. | 2015
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Histone methyltransferase Setdb1 regulates energy metabolism in hematopoietic stem and progenitor cellsKoide, Shuhei / Takubo, Keiyo / Oshima, Motohiko / Miyagi, Satoru / Saraya, Atsunori / Wang, Changshan / Matsui, Hirotaka / Kimura, Hiroshi / Shinkai, Yoichi / Suda, Toshio et al. | 2015
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SOX17 is critical for the maintenance of stem cell phenotype of intra-aortic hematopoietic clusters of cells in the aorta-gonad-mesonephros regionNobuhisa, Ikuo / Osawa, Mitsujiro / Uemura, Mami / Harada, Kaho / Anani, Maha / Saito, Kiyoka / Takagi, Haruna / Takahashi, Satomi / Kanai-Azuma, Masami / Kanai, Yoshiakira et al. | 2015
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UP-regulated TCRζ improves cytokine secretion in T cells from patients with AMLChen, Shaohua / Zha, Xiangfeng / Shi, Li / Yang, Lijian / Li, Bo / Wu, Xiuli / Zhang, Tao / Lu, Yuhong / Zhu, Kanger / Li, Yangqiu et al. | 2015
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Small molecule α9β1/α4β1 integrin antagonist mobilizes hematopoietic stem cells with long-term multilineage engraftment potentialCao, Benjamin / Zhang, Zhen / Grassinger, Jochen / Williams, Brenda / Nilsson, Susie et al. | 2015
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Ihstone H3 lysine 9 methylation is involved not only in maintaining epigenetic silencing, but is essential for setting up gene silencingKeniry, Andrew / Gearing, Linden / Jansz, Natasha / Liu, Joy / Kinkel, Sarah / Breslin, Kelsey / Moore, Darcy / Chen, Kelan / Pakusch, Miha / Willson, Tracy et al. | 2015
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See online program addendumGregory, Philip D. et al. | 2015
-
CDX2 regulates human leukemic cell clonogenicity and in vivo leukemia initiationPaczulla, Anna / Quintanilla-Martinez, Leticia / Kanz, Lothar / Lengerke, Claudia et al. | 2015
-
GATA2 reporter expression reveals stages of esc hematopoietic progenitor generation and facilitates study of GPR56 functionKauts, M.-L. / Kaimakis, P. / Solaimani, P. / Van der Linden, R. / Dzierzak, E. et al. | 2015
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Blood cells form from phenotypically distinct precursors during human blast colony differentiationBruveris, Freya / Ng, Elizabeth / Azzola, Lisa / Stanley, Edouard / Elefanty, Andrew et al. | 2015
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Probing co-operating somatic mutations in MLL-ENL driven myeloid leukemogenesisUgale, Amol S. / Adolfsson, Sofia / Säwen, Petter / Cammenga, Jörg / Bryder, David et al. | 2015
-
Glasgow prognostic score is superior to other inflammation-based scores in predicting survival of diffuse large B-cell lymphomaFeng, Ru et al. | 2015
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Investigation of the role of TRIB2 in normal murine hematopoiesisLiang, Kai Ling / O'Connor, Caitriona / McCarthy, Tommie V. / Keeshan, Karen et al. | 2015
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A novel 3D prostate cancer bone marrow metastasis in vitro model systemOthman Mosaad, Eman Mohamed / Chambers, Karen / Clements, Judith / Doran, Michael R. et al. | 2015
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TIM-3 and its ligand, galectin-9 constitute an autocrine loop to maintain stem cells in most human myeloid malignanciesAkashi, Koichi et al. | 2015
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Non-coding RNA editase deregulation as a driver of leukemia stem cell generationJamieson, Catriona et al. | 2015
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Clonal analysis of native hematopoiesisCamargo, Fernando D. et al. | 2015
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Micromarrow-direct bone marrow transplantation; using 3D mesenchymal stem/stromal cell (MSC) derived microtissues as a biological anchor to enhance haematopoietic stem cell (HSC) direct bone marrow delivery and engraftmentFutrega, Kathryn / Lott, William B. / Doran, Michael R. et al. | 2015
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Overexpression of the shortest isoform of histone demethylase LSD1 primes hematopoietic stem/progenitor cells for malignant transformationWada, Taeko / Koyama, Daisuke / Kikuchi, Jiro / Honda, Hiroaki / Furukawa, Yusuke et al. | 2015
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MLL-AF4 perturbs the self-renewal and differentiation potential of HSC during the definitive wave of haematopoiesis: A stage-specific patternMalouf, Camille / Kapeni, Chrysa / Ottersbach, Katrin et al. | 2015
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Development of thrombocytes from the megakaryocyte induced by thrombopoietin in frogTanizaki, Yuta / Murase, Ayaka / Mochizuki, Yoko / Otani, Takato / Kato, Takashi et al. | 2015
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STAT5-regulated microrna-193B controls hematopoietic stem cell expansion and leukemogenesis by modulating cytokine receptor signalingHaetscher, Nadine / Feuermann, Yonatan / Wingert, Susanne / Rehage, Maike / Thalheimer, Frederic B. / Bohnenberger, Hanibal / Mohr, Sebastian / Schroeder, Timm / Serve, Hubert / Oellerich, Thomas et al. | 2015
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Delineation of niches which support hematopoiesis in spleenLim, Hong K. / Periasamy, Pravin / Petvises, Sawang / O'Neill, Terence / O'Neill, Helen et al. | 2015
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Overexpression of RUNX1 short isoform plays a pivotal role in the development of myelodysplastic syndromes/myeloproliferative neoplasmsSakurai, Hiroko / Harada, Yuka / Matsui, Hirotaka / Nakajima, Hideaki / Kitamura, Toshio / Komatsu, Norio / Harada, Hironori et al. | 2015
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Declined presentation: Effect of Fbxw11 on the proliferation of lymphocytic leukemia cellsWang, Lina / Feng, Wenli / Yang, Xiao / Liao, Jinfeng / Ren, Qian / Yuan, Weiping / Zheng, Guoguang et al. | 2015
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Functional significance of MPL expression in the human hematopoietic stem cell compartmentMatsuoka, Yoshikazu / Sumide, Keisuke / Kawamura, Hiroshi / Nakatsuka, Ryusuke / Sasaki, Yutaka / Sonoda, Yoshiaki et al. | 2015
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Distinct and non-overlapping functions of Llgl1 and scribble in hematopoietic stem cellsMohr, Juliane / Frey, Stephanie / Bullinger, Lars / Schnoeder, Tina M. / Weinert, Soenke / Huber, Tobias B. / Kaehne, Thilo / Armstrong, Scott A. / Fischer, Thomas / Heidel, Florian H. et al. | 2015
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Quantification and visualization of dietary iron utilization under erythropoietic stimulation by using stable iron isotope 57FE and mass spectrometryMatsuo-Tezuka, Yukari / Noguchi-Sasaki, Mariko / Sasaki, Yusuke / Kondo, Kumiko / Kihara, Makoto / Kurasawa, Mitsue / Yorozu, Keigo / Shimonaka, Yasushi et al. | 2015
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Virus infections differentially modulate the cell cycle state and functionality of dormant long-term hematopoietic stem cells in vivoHirche, Christoph / Frenz, Theresa / Haas, Simon / Brizic, Ilija / Keyser, Kirsten / Döring, Marius / Halle, Stephan / Förster, Reinhold / Jonjic, Stipan / Messerle, Martin et al. | 2015
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Elucidating the post-natal role of SCA1+ thymic mesenchymal cellsPatenaude, Julien / Lemieux, Sébastien / Perreault, Claude et al. | 2015
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The AGM and the regulations of hematopoietic stem cell developmentDzierzak, Elaine et al. | 2015
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Local and systemic signaling in maintenance of hematopoietic progenitorsBanerjee, Utpal et al. | 2015
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From stem cells to T cells, in vitro applications and in vivo implicationsZúñiga-Pflücker, Juan Carlos et al. | 2015
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Improving humanized mice for hematology/hemato-oncology researchManz, Markus et al. | 2015
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Development of an ex vivo bone marrow mimicry microenvironment in a novel 3D hollow fibre bioreactorAllenby, Mark C. / Tahlawi, Asma / dos Santos, Susana Brito / Misener, Ruth / Hwang, Yu-Shik / Panoskaltsis, Nicki / Mantalaris, Athanasios et al. | 2015
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An investigation of the leukaemia initiating cell in TRIB2 mediated AMLPellicano, Francesca / O'Connor, Caitriona / Keeshan, Karen et al. | 2015
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Executive functions of the cascular niche in hematopoietic specification maintenance and regenerationRafii, Shahin et al. | 2015
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Role of long non-coding RNA PVT1 in proliferation of acute promyelocytic leukemiaZeng, Chengwu / Yu, Xibao / Cheng, Jingjing / Xu, Ling / Li, Yangqiu et al. | 2015
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Assessment of candidate microRNAs to supress leukemic cell function using an inducible lentiviral vector systemRuschmann, Jens / Maetzig, Tobias / Krowiorz, Kathrin / Kuchenbauer, Florian / Petriv, Oleh / Hansen, Carl / Humphries, Keith et al. | 2015
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HOXA gene expression defines definitive fetal hematopoietic cells differentiated from hESCsNg, Elizabeth / Azzola, Lisa / Bruveris, Freya / Elliott, David / Haylock, David / Nilsson, Susie / Stanley, Edouard / Elefanty, Andrew et al. | 2015
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Declined presentation T-cell precursors to generate chimeric antigen receptor (CAR)-modified t cellsDolnikov, Alla / Shen, Sylvie / Xu, Ning / Yang, Susan / O'Brien, Tracey et al. | 2015
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Amino acid metabolism in myeloid leukemiaHattori, Ayuna / Ito, Takahiro et al. | 2015
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Extracellular matrix protein Matn4 regulates HSC stress responseUckelmann, Hannah / Blaszkiewicz, Sandra / Essers, Marieke et al. | 2015
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Generation of primitive hematopoietic CD34+ CD235+ cells from iPS cells derived from human dental pulp mesenchymal stem cellsMora Roldan, German A. / Cevallos Guerra, Ricardo R. / Ramirez, Dalia / Camacho, Rosana Pelayo / Gazarian, Karlen et al. | 2015
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A novel CAMK2-SHH/BMP signaling axis discriminates the hematopoietic stem cell specification compartment of the sclerotomeClements, Wilson K. / Rothschild, Sarah C. / Kelley, Clair I. / Martin, Benjamin L. / Row, Richard H. et al. | 2015
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Effect of multipotent mesenchymal stroma cells (MSC) on acute myeloid leukemia (AML) cells in vitro and in vivoSchelker, Roland C. / Müller, Gunnar / Hart, Christina / Klatt, Sabine / Herr, Wolfgang / Grassinger, Jochen et al. | 2015
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Reprogramming adult mesenchymal stem cells into functional hematopoietic stem cells through transdetermination - from molecular mechanism to precise therapyYin, Qinwei et al. | 2015
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Declined presentation P38α–activated purine metabolism plays a crucial role in proliferation of transplanted hematopoietic stem cellsTakubo, Keiyo et al. | 2015
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CD97 expression influences migration and adhesion of FLT3-ITD positive acute myeloid leukemia cells and modulates the bone marrow stromal microenvironmentWobus, Manja / Oelschlägel, Uta / Ortlepp, Claudia / Jacobi, Angela / Bornhäuser, Martin et al. | 2015
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Declined presentation stem cell approach to generate chimeric antigen receptor modified immune effector cellsDolnikov, Alla / Shen, Sylvie / Xu, Ning / Yang, Susan / O'Brien, Tracey et al. | 2015
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Interferon regulatory factor-8 (IRF-8) regulates erythroblastic island morphology and functionYeo, Jia Hao / Xie, Vicki / Campbell, Iain / Fraser, Stuart et al. | 2015
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From HSC to megakaryocyte: differential role of the cellular components of the fetal liver microenvironmentEgard, Sebastien / Strassel, Catherine / Lanza, François / Gachet, Christian / Brouard, Nathalie et al. | 2015
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P-selectin expression and platelet function are developmentally regulatedPalis, James / Stolla, Massiel / McGrath, Kathleen E. / Kingsley, Paul D. et al. | 2015
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Identification of the human unipotent megakaryocyte progenitor, and its pathophysiological roles in human thrombopoietic disordersMiyawaki, Kohta / Iwasaki, Hiromi / Akashi, Koichi et al. | 2015
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Maintenance of hematopoietic stem and progenitor cell phenotype of intra-aortic cell clusters in the AGM region through the Sox17-Notch1-Hes1 axisSaito, Kiyoka / Nobuhisa, Ikuo / Anani, Maha / Harada, Kaho / Takahashi, Satomi / Taga, Tetsuya et al. | 2015
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Inhibition of GPR56 by PI-polyamide targeting the evi1-binding site with suppression of leukemiaKaneda, Kazuko N. / Saito, Yusuke / Suekane, Akira / Shimosaki, Shunsuke / Morishita, Kazuhiro et al. | 2015
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Title to come| 2015
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Comparative functional analysis of the molecular network of 7 selected MLL fusion proteinsSkucha, Anna / Stukalov, Alexey / Muhar, Matthias / Colinge, Jacques / Bennett, Keiryn / Zuber, Johannes / Superti-Furga, Giulio / Grebien, Florian et al. | 2015
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The focal adhesion protein ilk is key to niche interactions and survival of CML stem cellsRothe, Katharina / Watanabe, Akie / Forrest, Donna / Dedhar, Shoukat / Eaves, Connie / Jiang, Xiaoyan et al. | 2015
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Characterization of microglia-like cells derived from mouse bone marrow cells for new therapeutic strategy of alzheimer’s diseaseKawanishi, Shohei / Takata, Kazuyuki / Takada, Tetsuya / Kitamura, Yoshihisa / Ashihara, Eishi et al. | 2015
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Human cord blood-derived primitive CD34-negative hematopoietic stem cells (HSCs) are myeloid-biased long-term HSCs residing at the apex of human HSC hierarchyMatsuoka, Yoshikazu / Sumide, Keisuke / Kawamura, Hiroshi / Nakatsuka, Ryusuke / Fujioka, Tatsuya / Sasaki, Yutaka / Sonoda, Yoshiaki et al. | 2015
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NUP98-HOXA10HD knock in model: a good tool for the biology and regeneration of hematopoietic stem cellsDong, Yong / Xia, Chengxiang / Fang, Shumin / Liu, Xiaofei / Yang, Dan / wang, Jinyong et al. | 2015
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Unravelling the molecular events leading to hematopoietic stem cell generation in the mouse embryo aortaBaron, Chloe / Kester, Lennart / Boisset, Jean-Charles / van Oudenaarden, Alexander / Robin, Catherine et al. | 2015
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CLEC-2 signaling is crucial for the production of thrombopoietin in the megakaryocyte nicheNakamura-Ishizu, Ayako / Suda, Toshio et al. | 2015
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Notch signal strength controls endothelial to hematopoietic transitionBigas, Anna et al. | 2015
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The imaging of the bone marrow and hematopoietic stem cellsKunisaki, Yuya et al. | 2015
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Targeting intracellular trafficking of FLT3-ITD and KIT D816V by chlorpromazine shows promising preclinical activity against acute myeloid leukemia cellsRai, Shinya / Tanaka, Hirokazu / Watanabe, Toshio / Kanakura, Yuzuru / Matsumura, Itaru et al. | 2015
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Three-dimensional multicolor imaging of bone marrow cell populationsKokkaliaris, Konstantinos / Coutu, Daniel / Kunz, Leo / Schroeder, Timm et al. | 2015
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T cell-restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of lung macrophages in the lungIriguchi, Shoichi / Kikuchi, Norihiro / Noguchi, Emiko / Morishima, Yuko / Matsuyama, Masashi / Yoh, Keigyou / Takahashi, Satoru / Nakauchi, Hiromitsu / Ishii, Yukio / Kaneko, Shin et al. | 2015
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Defining the role of the phosphatase of regenerating liver enzymes in the immune systemHatzihristidis, Teri / Uetani, Noriko / Hardy, Serge / Sirois, Jacinthe / Tremblay, Michel L. et al. | 2015
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Declined presentation single-cell analysis of myelodysplastic sydrome stem cells during therapy and disease progressionPark, Christopher Y. / Vijay, Priyanka / Chung, Stephen S. / Stern, Diana / Klimek, Virginia / Mason, Christopher E. et al. | 2015
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A new gene transfer system for hematopoietic stem cells under physiological conditionTajima, Yoko / Yamazaki, Satoshi / Nakauchi, Hiromitsu et al. | 2015
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Declined presentation defining hematopoietic stem cell subtypes and their role in hematopoietic regeneration and ageingGrover, Amit / Sanjuan-Pla, Alejandra / de Teixeira Carelha, Joana / Thongjuea, Supat / Jacobsen, Sten Eirik W. / Nerlov, Claus et al. | 2015
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Fibroblastic colony forming units (CFU-F) within adherent cell layer from long-term bone marrow cultures correspond to the progeny of distinct mesenchymal precursor cellsBigildeev, ALexey / Sats, Natalia / Shipounova, Irina / Petinati, Natalia / Surin, Vadim / Cornils, Kerstin / Riecken, Kristoffer / Aranyossy, Tim / Fehse, Boris / Drize, Nina et al. | 2015
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Down-regulation of NDRG2 plays an important role in ATLL leukemogenesis via the PTEN-mediated PI3K/AKT signaling pathwayNakahata, Shingo / Ichikawa, Tomonaga / Yusuke, Saito / Arai, Yasuhito / Taki, Tomohiko / Taniwaki, Masafumi / Morishita, Kazuhiro et al. | 2015
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Roe of CBAP in controlling proliferation and development of T-cell acute lymphoblastic leukemiaChiang, Yun-Jung / Ho, Kun-Chin / Yang-Yen, Hsin-Fang / Yen, Jong-Young J. et al. | 2015
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A novel link between spliceosomal dysfunction and inflammationCameron, Rosannah C. / De, Adriana / Garza, La / Bowman, Teresa V. et al. | 2015
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Specific amino acid environments of bone marrow are crucial for the maintenance of hematopoietic stem cellsYamazaki, Satoshi / Nakauchi, Hiromitsu et al. | 2015
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CD14 mediates phagocytic activity during the granulocytic differentiation process in acute promyelocytic leukemia cellsHsu, Hui-Chi et al. | 2015
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TRGV and TRDV repertoire distribution and clonality of γδ T cells in patients with AMLJin, Zhenyi / Wu, Xiuli / Wang, Xinyu / Hu, Junyan / Chen, Shaohua / Yang, Lijian / Li, Yangqiu et al. | 2015
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Localization and characterization of hematopoietic cells in the mouse embryonic headLi, Zhuan / Vink, Chris S. / Mariani, Samanta / Dzierzak, Elaine et al. | 2015
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Lympho-hematopoietic microenvironment regulated by inter-organ communicationKatayama, Yoshio et al. | 2015
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The dynamic interplay of GATA zinc-fingers in blood development and diseaseNurmohamed, Salima et al. | 2015
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Hemogenic endothelium-like changes were observed in an adult human dermal fibroblast with poly (I:C) and an electrical stimulationMatsuo, Takuji / Sumiyoshi, Rhitsu / Shirasaki, Ryosuke / Yamamoto, Tadashi / Oka-Miura, Yoko / Matsumoto, Kennsuke / Ooi, Jun / Shirafuji, Naoki et al. | 2015
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Assessing the roles of cell cycle checkpoints in HSCBrown, Andreas / Pospiech, Johannes / Moehrle, Bettina / Martin, Nicola / Geiger, Hartmut et al. | 2015
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Local and systemic regularors of aging phenotypes in mammalian tissuesWagers, Amy J. et al. | 2015
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Noncoding RNA regulation of myeloid transcription factors, DNA methylation, and leukemiaTenen, Daniel G. et al. | 2015
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Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysisCabezas-Wallscheid, Nina / Klimmeck, Daniel / Hansson, Jenny / Lipka, Daniel B. / Reyes, Alejandro / Huber, Wolfgang / Milsom, Michael D. / Plass, Christoph / Krijgsveld, Jeroen / Trumpp, Andreas et al. | 2015
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ZEB2 drives immature t-cell lymphoblastic leukemia development via enhanced tumor initiating potential and increased IL-7 receptor signalingHaigh, Jody J. / Goossens, Steven et al. | 2015
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Endogenous MLL1 is dispensable for MLL-rearranged leukemia, but promotes acute leukemia driven by other oncoproteinsChen, Yufei / Li, Bin / Yokoyama, Akihiko / Ernst, Patricia et al. | 2015
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Activated KRAS enhances extramedullar engraftment and impairs clonogenic potential of MLLAF4-expressing cord blood CD34+ HSPCs but is not sufficient to initiate leukemiaPrieto, C. / Stam, Ronald / Ballerini, P. / Camos, M. / Marschalek, R. / Bursen, A. / Bueno, Clara / Menéndez, Pablo et al. | 2015
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Translational suppression of c-Myb by exosome micro-RNA constrains hematopoietic reserve in the AML NICHEHornick, Noah / Doron, Ben / Goloviznina, Natalya / Jianya, Huan / Kurre, Peter et al. | 2015
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Genome-wide DNA methylation profiling reveals two prognostically distinct subgroups of juvenile myelomonocytic leukemiaLipka, Daniel B. / Witte, Tania / Wiesenfarth, Manuel / Zucknick, Manuela / Konermann, Carolin / Gu, Lei / Claus, Rainer / Nöllke, Peter / Niemeyer, Charlotte / Flotho, Christian et al. | 2015
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Genomic studies of marrow failureShimamura, Akiko et al. | 2015
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Rejuvenation of aged hematopoietic stem cells by restoring the asymmetry of divisionFlorian, M.Carolina / Nattamai, Kalpana / Soller, Karin / Marka, Gina / Zheng, Yi / Geiger, Hartmut et al. | 2015
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Declined presentation the effects of interferon α-2b on defective bone marrow mesenchymal stem cells in patients with essential thrombocythemiaSun, Tiantian / Lv, Cuicui / Zhang, Donglei / Lv, Mingen / Zhang, Xian / Liu, Wenjie / Fu, Rongfeng / Li, Huiyuan / Xue, Feng / Liu, Xiaofan et al. | 2015
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AGE-associated clonal dominance of myeloid-biased HSC is underwritten by unique transcriptional and epigenetic alterationsBeerman, Isabel / Ziller, Michael / Vandiver, Amy / Gaudin, Raphael / Kirchhausen, Tomas / Feinberg, Andrew / Meissner, Alexander / Rossi, Derrick et al. | 2015
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The polarity protein, PAR3, is a key regulator of haematopoietic progenitorsDew, Alysha / Borg, Judy / Adolph, Leah / Russell, Sarah / Walkley, Carl / Purton, Louise E. / Ellis, Sarah L. et al. | 2015
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Mesenchymal stem cells from patients with CMML display impaired hematopoietic supportive activityShi, Hui / Li, Rong / Xing, Wen / Bai, Jie / Cheng, Tao / Yang, Fengchun / Zhou, Yuan et al. | 2015
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M-CSF instructs both cell division and cell identity in HSC through independent transcription factor circuitsSarrazin, Sandrine / Kandalla, Prashanth K. / Mossadegh-Keller, Noushine / Espinosa, Leon / Sieweke, Michael et al. | 2015
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Dietary created niche for non-myeloablative hematopoietic stem cell transplantationNakauchi, Hiromitsu et al. | 2015
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Role of septins in HSC agingSenger, Katharina / Florian, M.Carolina / Geiger, Hartmut et al. | 2015
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Genetic fate mapping of mesenchymal stem-like cells in the aorta-gonad mesonephros (AGM) and their contribution to developmental hematopoiesisChandrakanthan, Vashe / Knezevic, Kathy / Kang, Young C. / Qiao, Qiao / Pimanda, John et al. | 2015
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Rapid formation of B cell leukemia in mice expressing the PAX5-JAK2 fusion proteinJurado, Sabine / Kostanova, Daniela / Busslinger, Meinrad et al. | 2015
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Monitoring GM-CSF receptor/JAK2 activation in real time by live cell super-resolution fluorescence imagingYen, Jong-Young J. / Liu, Chun-Shan / Chien, FanChing / Hsieh, Thung-Han et al. | 2015
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Unraveling the importance of the post-transcriptional RNA regulon in leukemic stem cells by in vivo RNAide Rooij, Laura / Belew, Muluken / Hope, Kristin et al. | 2015
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The signaling balance between lysophosphatidic acid receptor 1 and 3 in bone marrow-derived mesenchymal stem cells determines progression of multiple myelomaKanehira, Masahiko / Fujiwara, Tohru / Nakajima, Shinji / Okitsu, Yoko / Onishi, Yasushi / Fukuhara, Noriko / Ichinohasama, Ryo / Harigae, Hideo et al. | 2015
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Modeling myeloid malignancies with human induced pluripotent stem cellsPapapetrou, Eirini et al. | 2015
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CD90 expression in mesenchymal stem cells of the malignant nicheJaganathan, Bithiah G. / Kumar, Atul / Bhattacharyya, Jina et al. | 2015
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Primitive macrophages control HSPC mobilisation and definitive haematopoiesisKissa, Karima et al. | 2015
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Functional perturbations in mesenchymal stromal cells from patients with acute myeloid leukemia and following high-dose irradiationLe, Y. / Chandran, P. / Richardson, R. / Allan, D. et al. | 2015
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Reprogramming primary human mature B-cells into induced pluripotent stem cellsBueno, Clara / Sardina, Jose Luis / Romero-Moya, Damià / Muñoz-Lopez, Alvaro / Di Stefano, Bruno / Quintana-Bustamante, Oscar / Segovia, Jose Carlos / Nakanishi, Mahito / Graf, Thomas / Menéndez, Pablo et al. | 2015
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Analysis of notch signalling activity during hematopoietic stem cell developmentGonzalez, Javier / Lendinez, Javier G. / Souilhol, Celine / Rybtsov, Stanislav / Hills, David / Zhao, Suling / Medvinsky, Alexander et al. | 2015
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Identifying mechanisms that limit efficient site-specific gene modification by homology-directed repair in hematopoietic stem cellsBjurström, Carmen F. / Mojadidi, Michelle / Campo, Beatriz / Reik, Andreas / Holmes, Michael C. / Cost, Greg / Gregory, Philip D. / Hoban, Megan D. / Hollis, Roger P. / Kohn, Donald B. et al. | 2015
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A MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fateGross, Atan / Maryanovich, Maria / Zaltsman, Yehudit et al. | 2015
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Unraveling the mechanisms underlying the refractoriness of MLL-rearranged acute B-cell leukemias to reprogramming into pluripotencyBueno, Clara / Romero-Moya, Damià / Muñoz-Lopez, Alvaro / van Roon, E. / Ramos, V. / Agraz, A. / Varela, I. / Ariza, L. / Castaño, J. / Giorgetti, A. et al. | 2015
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Metabolic regulation of hematopoietic stem cells by the bone marrow microenvironmentLapidot, Tsvee et al. | 2015
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Chromatin remodeling factor BRM is essential for the maintenance of HSC quiescenceNitta, Eriko / Yamashita, Masayuki / Oshima, Motohiko / Iwama, Atsushi / Suda, Toshio et al. | 2015
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Mechanism of FLT3 ligand dependent resistance to FLT3 inhibitorsChen, Fangli / Ishikawa, Yuichi / Kihara, Rika / Naoe, Tomoki / Kiyoi, Hitoshi et al. | 2015
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Making blood: The organized labor of multiple nichesScadden, David et al. | 2015
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Differentiation targeted compound screen of acute myeloid leukemiaBaudet, Aurelie / Ek, Fredrik / Davidsson, Josef / Soneji, Shamit / Olsson, Roger / Cammenga, Jörg / Magnusson, Mattias / Juliusson, Gunnar et al. | 2015
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Modeling the function of the cohesin complex in hematopoietic stem cell differentiation and transformationAifantis, Iannis et al. | 2015
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Dual function of fumarate hydratase in haematopoietic stem cell fatesGuitart, Amelie V. / Vukovic, Milica / Sepulveda, Catarina / Panagopoulou, Theano / Allen, Lewis / Pollard, Patrick / Morton, Nik / Finch, Andy / Kranc, Kamil et al. | 2015
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IRF8 inhibits the activity of C/EBPα to restrain mononuclear phagocyte progenitors from differentiating into neutrophilsKurotaki, Daisuke / Yamamoto, Michio / Nishiyama, Akira / Uno, Kazuhiro / Ban, Tatsuma / Ichino, Motohide / Sasaki, Haruka / Matsunaga, Satoko / Yoshinari, Masahiro / Ryo, Akihide et al. | 2015
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Prospective isolation of human hematopoietic stem cell-supportive mesenchymal stem/stromal cells from human bone marrowMatsuoka, Yoshikazu / Sumide, Keisuke / Kawamura, Hiroshi / Nakatsuka, Ryusuke / Fujioka, Tatsuya / Sasaki, Yutaka / Sonoda, Yoshiaki et al. | 2015
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A low-input, multiplexed assay for quantitative comparison of chromatin landscapesvan Galen, Peter / Ram, Oren / Ryan, Russel J. / Cotton, Matthew J. / Donohue, Laura / Drier, Yotam / Sievers, Cem / Gillespie, Shawn M. / Bernstein, Bradley E. et al. | 2015
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DNMT3A and TET2 cooperate and compete to prevent leukemogenesisGoodell, Margaret A. et al. | 2015
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Ion transport-associated molecules as therapeutic targets against glioblastoma stem cellsTakada, Tetsuya / Takata, Kazuyuki / Ashihara, Eishi et al. | 2015
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Down-regulated micrornas in plasma and red blood cells of patients with malaria infectionChamnanchanunt, Supat / Okada, Kazuhiro / Desakorn, Varunee / Koga, Misaki / Nakamura, Yuuri / Shiotsu, Hiromichi / Fucharoen, Suthat / Umemura, Tsukuru et al. | 2015
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Comparative RNA-seq analyses identify new microRNA biomarkers and candidate target genes in patients’ drug-resistant CD34+ CML stem/progenitor cellsLin, Hanyang / Rothe, Katharina / Ruschmann, Jens / Petriv, Oleh / O'Neill, Kieran / Knapp, David / Brinkman, Ryan / Birol, Inanc / Forrest, Donna / Hansen, Carl et al. | 2015
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Embryonic stem cell-derived B cells engraft in immunodeficient mice, recapitulating YS B lymphopoiesisLin, Yang / Yoder, Mervin C. / Yoshimoto, Momoko et al. | 2015
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Targeted single copy Runx1 reporter lines for interrogation and enhancement of definitive hematopoiesis from murine pluripotent stem cellsWebber, Beau R. / Tolar, Jakub / Kyba, Michael / Blazar, Bruce R. et al. | 2015
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Overcoming quiescence by targeting p21 (Cdkn1a) sensitizes pre-leukemic stem cells to chemotherapyTremblay, Cedric S. / Saw, Jesslyn / Chiu, Sung K. / Curtis, David et al. | 2015
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Abnormalities in nestin-expressing bone marrow stromal cells in patients with myelodysplastic syndromeObara, Naoshi / Chiba, Shigeru / Kato, Takayasu / Sakamoto, Tatsuhiro / Cao, Luan / Suzuki, Sachie / Kurita, Naoki / Yokoyama, Yasuhisa / Sakata, Mamiko / Hasegawa, Yuichi et al. | 2015
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Development of human hemato-lymphoid system in human cytokine knock-IN RAG2-/-IL2RG-/- mice engrafted with peripheral blood mobilized CD34+ cellsSaito, Yasuyuki / Ellegast, Jana M. / Kull, Daniel / Heikenwälder, Mathias / Flavell, Richard A. / Manz, Markus G. et al. | 2015
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Migration and characteristics of thrombocytes during cold-exposure in xenopus laevisMurase, Ayaka / Kashiwase, Nao / Tanizaki, Yuta / Otani, Takato / Mochizuki, Yoko / Kato, Takashi et al. | 2015
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New insights into the endothelial-to-haematopoietic transition leading to HSC emergenceLacaud, Georges / Thambyrajah, Roshana / Mazan, Milena / Patel, Rahima / Moignard, Victoria / Stefanska, Monika / Marinopoulou, Elli / Li, Yaoyong / Lancrin, Christophe / Clapes, Thomas et al. | 2015
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Editorial Board| 2015
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The dominant mechanism of prenatal platelet-formation is not via proplatelet intermediates but by direct releasePotts, Kathryn S. / Dawson, Caleb A. / Taoudi, Samir et al. | 2015
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Introduction of hematopoietic stem cell nicheArai, Fumio et al. | 2015
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Granulocyte-colony stimulating factor specifically mobilizes dormant hematopoietic stem cells without proliferationBernitz, Jeff / Moore, Kateri et al. | 2015
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Role of bone marrow microenvironment in myeloid leukemia progressionKumar, Atul / Bhattacharyya, Jina / Jaganathan, Bithiah G. et al. | 2015
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Delayed addition of epoetin beta during storage: Effect on peripheral erythrocyte divisionNiimi, Gen et al. | 2015
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Inclusion of conditioned medium of mesenchymal stem cells in the freezing medium imparts cryoprotective effect on the ex vivo expanded umbilical cord blood cellsKadekar, Darshana / Rangole, Sonal / Kale, Vaijayanti / Limaye, Lalita et al. | 2015
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A novel role for the EMT regulator, snai1, in hematopoiesis and leukemiaCarmichael, Catherine / Goossens, Steven / Kile, Benjamin / Haigh, Jody J. et al. | 2015
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Microrna can completely rescue b lineage commitment arrest due to early B cell factor 1 deficiency—can micrornas control cell fate as an alternative to transcription factors?Chanda, B. / Kotani, Ai et al. | 2015
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Regeneration kinetics of hematopoietic stem cells in wild-type and P53-deficient mice after sublethal cyclophosphamide treatmentSefc, Ludek / Paral, Petr / Necas, Emanuel et al. | 2015
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Chloroquine inhibits autophagy and induces the apoptosis of primary effusion lymphoma via ER stressAlam, Md. Masud / Kariya, Ryusho / Matsuda, Kouki / Okada, Seiji et al. | 2015
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PDGF-AB and azacitidine induced reprogramming of somatic cells into tissue regenerative multipotent stem cellsChandrakanthan, Vashe / Jair, Kwan / Oliver, Rema / Qiao, Qiao / Kang, Young C. / Zarzour, Peter / Beck, Dominik / Boelen, Lies / Unnikrihnan, Ashwin / Villanueva, Jeanette et al. | 2015
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Axolotl hematopoietic stem cells share similar functional characteristics with their mammalian counterpartsRodgers, Anna K. / Lopez, David / Lin, Li / Maden, Malcolm / Scott, Edward W. et al. | 2015
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Factors released by megakaryocytes thrombin cleave osteopontin to negatively regulate hematopoietic stem cellsHeazlewood, Shen / Storan, Melonie / Heazlewood, Chad / Cao, Benjamin / Alexander, Warren / Neaves, Rebecca / Oteiza, Ana / Nilsson, Susie et al. | 2015
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Declined presentation Dendritic cell vaccination as a post-remission treatment in acute myeloid leukemiaBerneman, Zwi / de Velde, Ann Van / Anguille, Sébastien / Nijs, Griet / Stein, Barbara / Cools, Nathalie / Vermeulen, Katrien / Maes, Marie-Berthe / Willemen, Yannick / Granacher, Nikki et al. | 2015
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Biological and genetic characterization of the role of SRSF2 mutations in the pathogenesis of myelodysplastic syndromesKon, Ayana / Yamazaki, Satoshi / Kataoka, Keisuke / Yoshizato, Tetsuichi / Shiozawa, Yusuke / Sanada, Masashi / Yoshida, Kenichi / Nagata, Yasunobu / Shiraishi, Yuichi / Miyano, Satoru et al. | 2015
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Exploring the role of kit ligand at the onset of hematopoiesisAzzoni, Emanuele / Nerlov, Claus / De Bruijn, Marella et al. | 2015
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Stem cell in cancer: Do they matter?Dick, John E. et al. | 2015
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Enforced expression of RPS19 derived from human elongation factor 1A short (EFS) promoter corrects the anemia and lethal bone marrow failure in mouse model for RPS19-deficient diamond-blackfan anemiaDebnath, Shubhranshu / Jaako, Pekka / Siva, Kavitha / Modlich, Ute / Schambach, Axel / Gaspar, Bobby / Flygare, Johan / Karlsson, Stefan et al. | 2015
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Inactivation of EZH2 by trancated form mutaion de-represses novel target genes to promote tumor-initiating capacityKawabata, Kimihito Cojin / Inoue, Daichi / Goyama, Susumu / Harada, Hironori / Kitaura, Jiro / Kitamura, Toshio et al. | 2015
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A fully validated blood stem/progenitor cell regulatory network reveals mechanisms of cell state stabilisationSchütte, Judith / Wang, Huange / Jarrett, Andrew / Riepsaame, Joey / Wilson, Nicola / Antoniou, Stella / Calero-Nieto, Fernando / Basilico, Silvia / Kinston, Sarah / Hannah, Rebecca et al. | 2015
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Maintenance and expansion of human hematopoietic stem and progenitor cells in the presence of defined factors aloneSudo, Kazuhiro / Yamazaki, Satoshi / Nakauchi, Hiromitsu / Nakamura, Yukio et al. | 2015
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Global regulatory networks and Myc regulation in HSCs and early progenitorsTrumpp, Andreas et al. | 2015
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Deciphering the role of retinoic acid receptor signalling in haematopoietic stem cellsLauridsen, Felicia K. / Porse, Bo et al. | 2015
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Common myeloid progenitors are made up of distinct subpopulations that either yield erythrocytes or myeloid cellsPerié, Leila / Duffy, Ken R. / de Boer, Rob J. / Schumacher, Ton et al. | 2015
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No hierarchical heterogeneity in adult B-ALL lymphoid neoplasiaJiang, Zhiwu / Deng, Manman / xu, Bing / Li, Peng et al. | 2015
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Stem cell factor, GM-CSF, and IL-3-Transgenic humanized mice develop fatal hemophagocytic lymphohistiocytosisYoshihara, Satoshi / Li, Yuying / Xia, Jinxing / Li, Wei / Fujimori, Yoshihiro / Yang, Yong-Guang et al. | 2015
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It's all kicking off: Understanding the initiation of childhood leukaemia during pregnancyMansell, Els / Case, Patrick et al. | 2015
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Rictor is pivotal for the emergence and function of embryonic hematopoietic stem cellsWang, Weili / He, Wenyan / Mu, Xiaohuan / Zhou, Jie / Ni, Yanli / Zhao, Yunze / Wang, Xiaomin / Wang, Qianfei / Cheng, Tao / Liu, Bing et al. | 2015
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Musashi-2 postranscriptionally attenuates aryl hydrocarbon receptor signaling to expand human hematopoietic stem cellsRentas, Stefan / Holzapfel, Nicholas / Belew, Muluken / Voisin, Veronique / Pratt, Gabriel / Bader, Gary / Yeo, Gene / Hope, Kristin et al. | 2015
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Angiogenesis revisited: Endothelial cell metabolism as a target?Carmeliet, Peter et al. | 2015
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CALM plays a critical role for oncogenic activity of RTK mutants and would be a promising therapeutic targetTanaka, Hirokazu / Rai, Shinya / Watanabe, Toshio / Kanakura, Yuzuru / Matsumura, Itaru et al. | 2015
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Tissue-resident macrophages originate from yolk sac-derived erythro-myeloid progenitorsPerdiguero, Elisa Gomez / Klapproth, Kay / Schulz, Christian / Busch, Katrin / Azzoni, Emanuele / Crozet, Lucile / Garner, Hannah / Trouillet, Celine / De Bruijn, Marella / Geissmann, Frederic et al. | 2015
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Molecular mechanism of M-CSF-mediated lineage instructionEndele, Max / Schroeder, Timm et al. | 2015
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Hematopoietic stem cell production and regulation in the embryo aortaRobin, Catherine et al. | 2015
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Anti tumor activity of fucoidan in acute promyelocytic leukemia and its synergy with arsenic trioxide and ATRA in vitro and in vivoAtashrazm, Farzaneh / Lowenthal, Ray M. / Woods, Greg M. / Holloway, Adele F. / Dickinson, Joanne L. et al. | 2015
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Cohesin genes are critical regulators of HSC renewalGaleev, Roman / Baudet, Aurelie / Kvist, Anders / Törngren, Therese / Larsson, Jonas et al. | 2015
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Declined presentation recombinant human thrombopoietin promotes hematopoietic reconstitution in miceLi, Yanhua / Wang, Chao / Zhang, Bowen / Wang, Sihan / He, Lijuan / Pei, Xuetao et al. | 2015
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Physiologic stress drives accelerated aging of hematopoietic stem cellsMilsom, Michael D. et al. | 2015
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Protection of telomeres 1 (Pot1) regulates hematopoietic stem cell activity during ageingHosokawa, Kentaro / MacArthur, Ben D. / Hanazawa, Shigemasa / Suda, Toshio / Arai, Fumio et al. | 2015
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P53 mediates loss of hematopoietic stem cells in MIR-142A-3P mutantsLiu, Feng et al. | 2015
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Defining stem cells and regulatory networks by single cell profilingGottgens, Bertie et al. | 2015
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A stress-responsive transcriptional factor NRF2 activates hematopoietic stem cellsMurakami, Shohei / Yamamoto, Masayuki / Motohashi, Hozumi et al. | 2015
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Disrupting cdkn1a secondary to FLT3/ITD inhibition is responsible for resistance to FLT3/ITD inhibitor AC220 in FLT3/ITD+ cellsFukuda, Seiji / Abe, Mariko / Hirade, Tomohiro / Yamaguchi, Seiji et al. | 2015
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Automated imaging and analysis of hematopoietic CFU assays of mouse bone marrowKhojasteh, Mehrnoush / Walasek, Marta A. / Wognum, Albertus W. / Szilvassy, Stephen J. / Egeler, Oliver / Woodside, Steven / Poon, Steven / Thomas, Terry / Eaves, Allen et al. | 2015
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Pluripotent stem cell models of reticular dysgenesis as a tool for elucidating the potential role of intracellular bioenergetic systems on controlling the fate of hematopoietic progenitorsSaiki, Norikazu / Oshima, Koichi / Hirayama, Akiyoshi / Soga, Tomoyoshi / Tomita, Masaru / Nakahata, Tatsutoshi / Saito, Megumu K. et al. | 2015
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Dynamics of hematopoietic cell cluster emergence in hemogenic endotheliumZape, Joan M. / Lizama, Carlos / Bos, Frank / Hawkins, John / Zovein, Ann C. et al. | 2015
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Cytokine signalling in developmental haematopoiesis reveals resistance of embryonic haematopoietic stem cells to myeloproliferative disease-associated mutationMascarenhas, Maria I. / Bacon, Wendi A. / Kapeni, Chrysa / Fitch, Simon R. / Li, Juan / Green, Anthony R. / Ottersbach, Katrin et al. | 2015
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Mutation of the SF3B1 predict a poor prognosis in japanese CLL patientsMitsui, Takeki / Koiso, Hiromi / Namahashi, Hirotaka / Saito, Akio / Ishizaki, Takuma / TAakizawa, Makiko / Yokohama, Akihiko / Saito, Takayuki / Jinbo, Takahiro / Ogura, Hidemi et al. | 2015
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Declined presentation Role of MYBL2 haploinsufficiency in the development of age-related myeloid malignanciesCancian, Laila / Reeve, Natasha / Ward, Carl / Petermann, Eva / Garcia, Paloma et al. | 2015
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Cytotoxic therapies cause irreversible damage to the niches for multipotent progenitor cells, resulting in impaired long-term repopulating potential of bone marrowPurton, Louise E. et al. | 2015
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Loss of canonical notch signaling affects multiple steps in natural killer (NK) cell developmentChaves, Patricia / Zriwil, Alya / Boukarabila, Hanane / Jacobsen, Sten Eirik W. / Sitnicka, Ewa et al. | 2015
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Identification of common monocyte progenitors, pre-monocytes, and granulocyte monocyte progenitors in human umbilical cord bloodKawamura, Shunsuke / Onai, Nobuyuki / Takenaka, Katsuto / Akashi, Koichi / Ohteki, Toshiaki et al. | 2015
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A novel three-dimensional co-culture system can maintain leukemic hematopoiesisBalandran, Juan C. / Enciso, Jennifer / Espinoza, Nancy A. / Piña-Sánchez, Patricia / Vadillo, Eduardo / Jimenez-Hernández, Elva / Mayani, Hector / Ortiz-Navarrete, Vianney / Camacho, Rosana Pelayo / Guzma, Monica et al. | 2015
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Hepatic leukemia factor is essential for maintaining hematopoietic stem cell functionKomorowska, Karolina / Doyle, Alexander / Soneji, Shamit / Hultmark, Simon / Bryder, David / Mikkola, Hanna / Larsson, Jonas / Magnusson, Mattias et al. | 2015
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Defect in pre-ribosomal RNA processing is involved in myeloid leukemogenesisMatsui, Hirotaka / Kanai, Akinori / Nagamachi, Akiko / Okuno, Moe / Inaba, Toshiya et al. | 2015
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IFNα promotes differentiation of BCR-ABL+ leukemic cells through upregulating C/EBPβYokota, Asumi / Hirai, Hideyo / Hayashi, Yoshihiro / Tamura, Akihiro / Sato, Atsushi / Iwasa, Masaki / Fujishiro, Aya / Shoji, Tsukimi / Miura, Yasuo / Maekawa, Taira et al. | 2015
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FACS-segregated c-kithigh and c-kitlow cells in the murine hematopoietic stem cell compartment are functionally distinctSasaki, Yutaka / Matsuoka, Yoshikazu / Nakatsuka, Ryusuke / Sumide, Keisuke / Kawamura, Hiroshi / Fujioka, Tatsuya / Sonoda, Yoshiaki et al. | 2015
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Declined presentation one dose of 5-AZA-2'-Deoxycytidine enhances therapeutic efficacy of cart-cell therapy in a murine model by improving T-cell persistenceDolnikov, Alla / Yang, Susan / Shen, Sylvie / Xu, Ning / O'Brien, Tracey et al. | 2015
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Long-term single cell quantification: new tools for old questionsSchroeder, Timm et al. | 2015
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The role of CDKN1C/P57KIP2 in developmental haematopoiesisKapeni, Chrysa / Ottersbach, Katrin et al. | 2015
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Redefining the human blood progenitor hierarchy across developmentZandi, Sasan / Notta, Faiyaz / Takayama, Naoya / Dobson, Stephanie / Gan, Olga / Kaufmann, Kerstin B. / McLeod, Jessica / Dick, John E. et al. | 2015
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Targeting pre-leukemic stem cells in T-acute lymphoblastic leukemiaGerby, Bastien / Laflamme, Guillaume / Kwok, Benjamin / Roux, Philippe / Hébert, Josée / Sauvageau, Guy / Hoang, Trang et al. | 2015
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Asymmetric cell division of hematopoietic stem cellsLoeffler, Dirk / Schroeder, Timm et al. | 2015
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Mitochondrial dynamics regulate lineage potential of hematopoietic stem cellsLuchsinger, Larry / Almeida, Mariana Justino / Snoeck, Hans et al. | 2015
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Declined presentation AMPK protects acute myeloid leukemia-initiating cells residing in the bone marrow after metabolic stressNakada, Daisuke et al. | 2015
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Identification and functional characterization of early stress erythroid progenitors using novel surface markers and in vivo tracingSoderberg, Sofie Singbrant / Mattebo, Alexander / Flygare, Johan et al. | 2015
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Declined presentation inflammatory modulation of hematopoietic stromal niche cells by TNF-α leads to rapid mobilization of hematopoietic stem/progenitor cells (HSPC) and neutrophilsPark, Shin-Young / Anna Han, Eun Young / Jung, Yookyung / Lin, Charles P. / Silberstein, Leslie E. et al. | 2015
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CD11B+CX3CR1+ cells play a determining role in reparative angiogenesis after ischemic injuryKim, Jeong-A / Kwak, Jae-Yong / Noh, Kyoungmi / Lee, Joon et al. | 2015
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A stromal organiser cell that directs neonatal spleen regenerationTan, Jon / Watanabe, Takeshi et al. | 2015
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The clinical impact of both point mutated and alternatively spliced BCR-ABL in CML patients: result of highly-sensitive, deep sequencing studyYuda, Junichiro / Miyamoto, Toshihiro / Odawara, Jun / Ohkawa, Yasuyuki / Akashi, Koichi et al. | 2015
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Unipotent megakaryopoietic pathway bridging hematopoietic stem cells and mature megakaryocytesNishikii, Hidekazu / Umemoto, Terumasa / Goltsev, Yury / Matsuzaki, Yu / Yamato, Masayuki / Nolan, Garry / Negrin, Robert / Chiba, Shigeru et al. | 2015
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RNAi screen identifies cytohesin1 as a mediator of adhesion in human hematopoietic stem/progenitor cellsRak, Justyna M. / Foster, Katie / Potrzebowska, Katarzyna / Talkhoncheh, Mehrnaz Safaee / Komorowska, Karolina / Törngren, Therese / Kvist, Anders / Svensson, Lena / Bonnet, Dominique / Larsson, Jonas et al. | 2015
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Autologous haematopoietic stem cell transplantation requires recipient BM macrophagesKaur, Simranpreet / Raggatt, Liza J. / Jacobsen, Rebecca / Millard, Susan / Barbier, Valerie / Nowlan, Bianca / Winkler, Ingrid G. / MacDonald, Kelli P. / Perkins, Andrew C. / Hume, David A. et al. | 2015
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Megakaryocyte-platelet induction from mouse embryonic stem cells by enforced expression of Gata2 in late hemogenic endothelial cellsKawaguchi, Manami / Kitajima, Kenji / Kanokoda, Mai / Suzuki, Hidenori / Nakajima, Marino / Kasahara, Kohji / Hara, Takahiko et al. | 2015
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Normal and neoplastic stem cellsWeissman, Irving et al. | 2015
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Medial HOXA gene expression is required for establishing “stemness” in human HSCsDou, Diana R. / Calvanese, Vincenzo / Sierra, Maria I. / Sasidharan, Rajkumar / Zack, Jerome A. / Crooks, Gay M. / Galic, Zoran / Mikkola, Hanna et al. | 2015
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Stroma-derived osteopontin regulates HSC agingGuidi, Novella / Sacma, Mehmet / Soller, Karin / Marka, Gina / Weiss, Johannes / Cancelas, Jose / Florian, M.Carolina / Geiger, Hartmut et al. | 2015
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SSB1 and SSB2 single-stranded DNA binding proteins are essential for HSC functionVu, Therese / Shi, Wei / Lane, Steven / Khanna, Kum Kum et al. | 2015
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Declined presentation high HIF-1α level results in murine MDS/MPN or HLH in different mouse backgroundsHayashi, Yoshihiro / Yan, Xiaomei / Xiao, Zhijian / Huang, Gang et al. | 2015
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Renin-angiotensin system is involved in hematopoietic emergenceJulien, Emmanuelle / Lanza, François / Gachet, Christian / Tavian, Manuela et al. | 2015
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Declined presentation Vβ17 T cell clones may respond to ABL-T315I mutation protein in chronic myeloid leukemia in blastic crisisXu, Ling / Chen, Jie / Zhang, Tao / Zha, Xianfeng / Chen, Shaohua / Yang, Lijian / Lu, Yuhong / Zhu, Kanger / Li, Yangqiu et al. | 2015