A Targeted Library of Small-Molecule, Tyrosine, and Dual-Specificity Phosphatase Inhibitors Derived from a Rational Core Design and Random Side Chain Variation (Englisch)
- Neue Suche nach: Rice, R. L.
- Neue Suche nach: Rusnak, J. M.
- Neue Suche nach: Yokokawa, F.
- Neue Suche nach: Yokokawa, S.
- Neue Suche nach: Messner, D. J.
- Neue Suche nach: Boynton, A. L.
- Neue Suche nach: Wipf, P.
- Neue Suche nach: Lazo, J. S.
- Neue Suche nach: Rice, R. L.
- Neue Suche nach: Rusnak, J. M.
- Neue Suche nach: Yokokawa, F.
- Neue Suche nach: Yokokawa, S.
- Neue Suche nach: Messner, D. J.
- Neue Suche nach: Boynton, A. L.
- Neue Suche nach: Wipf, P.
- Neue Suche nach: Lazo, J. S.
In:
BIOCHEMISTRY -PENNSYLVANIA THEN WASHINGTON-
;
36
, 50
;
15965-15974
;
1997
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ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:A Targeted Library of Small-Molecule, Tyrosine, and Dual-Specificity Phosphatase Inhibitors Derived from a Rational Core Design and Random Side Chain Variation
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Beteiligte:Rice, R. L. ( Autor:in ) / Rusnak, J. M. ( Autor:in ) / Yokokawa, F. ( Autor:in ) / Yokokawa, S. ( Autor:in ) / Messner, D. J. ( Autor:in ) / Boynton, A. L. ( Autor:in ) / Wipf, P. ( Autor:in ) / Lazo, J. S. ( Autor:in )
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Erschienen in:BIOCHEMISTRY -PENNSYLVANIA THEN WASHINGTON- ; 36, 50 ; 15965-15974
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Verlag:
- Neue Suche nach: ACS AMERICAN CHEMICAL SOCIETY
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Erscheinungsdatum:01.01.1997
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Format / Umfang:10 pages
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ISSN:
-
Medientyp:Aufsatz (Zeitschrift)
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Format:Print
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Sprache:Englisch
- Neue Suche nach: 574 / 612.015
- Weitere Informationen zu Dewey Decimal Classification
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Klassifikation:
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Datenquelle:
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- 15555
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Slowed Enzymatic Turnover Allows Characterization of Intermediates by Solid-State NMR †Studelska, Daniel R. / McDowell, Lynda M. / Espe, Matthew P. / Klug, Christopher A. / Schaefer, Jacob et al. | 1997
- 15561
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Purealin Blocks the Sliding Movement of Sea Urchin Flagellar Axonemes by Selective Inhibition of Half the ATPase Activity of Axonemal Dyneins †Fang, Yang-Il / Yokota, Etsuo / Mabuchi, Issei / Nakamura, Hideshi / Ohizumi, Yasushi et al. | 1997
- 15568
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Participation of the N-Terminal Region of Cε3 in the Binding of Human IgE to Its High-Affinity Receptor FcεRI †Henry, Alistair J. / Cook, Justin P. D. / McDonnell, James M. / Mackay, Graham A. / Shi, Jianguo / Sutton, Brian J. / Gould, Hannah J. et al. | 1997
- 15568
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Participation of the N-Terminal Region of Ce3 in the Binding of Human IgE to Its High-Affinity Receptor FceRIHenry, Alistair J. et al. | 1997
- 15579
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Identification of Contact Residues in the IgE Binding Site of Human FcεRIα †Cook, Justin P. D. / Henry, Alistair J. / McDonnell, James M. / Owens, Raymond J. / Sutton, Brian J. / Gould, Hannah J. et al. | 1997
- 15579
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Identification of Contact Residues in the IgE Binding Site of Human FceRIaCook, Justin P.D. et al. | 1997
- 15589
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Ionic Properties of Membrane Association by Vitamin K-Dependent Proteins: The Case for Univalency †McDonald, John F. / Evans,, Thomas C. / Emeagwali, Dale Brown / Hariharan, Meena / Allewell, Norma M. / Pusey, Marc L. / Shah, Amit M. / Nelsestuen, Gary L. et al. | 1997
- 15599
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pH Dependence of Antibody/Lysozyme Complexation †Gibas, Cynthia J. / Subramaniam, Shankar / McCammon, J. Andrew / Braden, Bradford C. / Poljak, Roberto J. et al. | 1997
- 15615
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Regulation of Protein Kinase C βII by Its C2 Domain †Edwards, Amelia S. / Newton, Alexandra C. et al. | 1997
- 15615
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Regulation of Protein Kinase C bII by Its C2 DomainEdwards, n.Amelia S. et al. | 1997
- 15624
-
Mapping the Suramin-Binding Sites of Human Neutrophil Elastase: Investigation by Fluorescence Resonance Energy Transfer and Molecular Modeling †Mély, Yves / Cadène, Martine / Sylte, Ingebrigt / Bieth, Joseph G. et al. | 1997
- 15632
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Ligand-Induced Conformational Changes in Lactose Repressor: A Fluorescence Study of Single Tryptophan Mutants †Barry, Jennifer K. / Matthews, Kathleen S. et al. | 1997
- 15643
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Identification of Catalytically Important Residues in Yeast Transketolase †Wikner, Christer / Nilsson, Ulrika / Meshalkina, Ludmilla / Udekwu, Cecilia / Lindqvist, Ylva / Schneider, Gunter et al. | 1997
- 15650
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Acyl-Adenylate Motif of the Acyl-Adenylate/Thioester-Forming Enzyme Superfamily: A Site-Directed Mutagenesis Study with the Pseudomonas sp. Strain CBS3 4-Chlorobenzoate:Coenzyme A Ligase †Chang, Kai-Hsuan / Xiang, Hong / Dunaway-Mariano, Debra et al. | 1997
- 15660
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Structural and Biochemical Characterization of the GTPgS-, GDP.Pi-, and GDP-Bound Forms of a GTPase-Deficient Gly42 -->Val Mutant of Gia1Raw, Andre S. et al. | 1997
- 15660
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Structural and Biochemical Characterization of the GTPgammaS-, GDPP~i-, and GDP-Bound Forms of a GTPase-Deficient Gly^4^2 -> Val Mutant of G~i~a~1Raw, A. S. / Coleman, D. E. / Gilman, A. G. / Sprang, S. R. et al. | 1997
- 15660
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Structural and Biochemical Characterization of the GTPγS-, GDP·Pi-, and GDP-Bound Forms of a GTPase-Deficient Gly42 → Val Mutant of Gi α 1 †Raw, Andre S. / Coleman, David E. / Gilman, Alfred G. / Sprang, Stephen R. et al. | 1997
- 15670
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Role of the Extracellular Loops of the Thyrotropin-Releasing Hormone Receptor: Evidence for an Initial Interaction with Thyrotropin-Releasing Hormone †Perlman, Jeffrey H. / Colson, Anny-Odile / Jain, Rahul / Czyzewski, Bryan / Cohen, Louis A. / Osman, Roman / Gershengorn, Marvin C. et al. | 1997
- 15677
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Role of g-Carboxyglutamic Acid in the Calcium-Induced Structural Transition of Conantokin G, a Conotoxin from the Marine Snail Conus geographusRigby, Alan C. et al. | 1997
- 15677
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Role of gamma-Carboxyglutamic Acid in the Calcium-Induced Structural Transition of Conantokin G, a Conotoxin from the Marine Snail Conus geographusRigby, A. C. / Baleja, J. D. / Li, L. / Pedersen, L. G. / Furie, B. C. / Furie, B. et al. | 1997
- 15677
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Role of γ-Carboxyglutamic Acid in the Calcium-Induced Structural Transition of Conantokin G, a Conotoxin from the Marine Snail Conus geographus † , ‡Rigby, Alan C. / Baleja, James D. / Li, Leping / Pedersen, Lee G. / Furie, Barbara C. / Furie, Bruce et al. | 1997
- 15685
-
Folding Dynamics of the src SH3 Domain †Grantcharova, Viara P. / Baker, David et al. | 1997
- 15693
-
Three-Dimensional Solution Structure of α-Conotoxin MII, an α3β2 Neuronal Nicotinic Acetylcholine Receptor-Targeted Ligand † , ‡Shon, Ki-Joon / Koerber, Steven C. / Rivier, Jean E. / Olivera, Baldomero M. / McIntosh, J. Michael et al. | 1997
- 15693
-
Three-Dimensional Solution Structure of a-Conotoxin MII, an a3,B2 Neuronal Nicotinic Acetylcholine Receptor-Targeted LigandShon, Ki-Joon et al. | 1997
- 15701
-
Tyrosine and Tryptophan Structure Markers in Hemoglobin Ultraviolet Resonance Raman Spectra: Mode Assignments via Subunit-Specific Isotope Labeling of Recombinant Protein †Hu, Xuehua / Spiro, Thomas G. et al. | 1997
- 15713
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Flavin Conformational Changes in the Catalytic Cycle of p-Hydroxybenzoate Hydroxylase Substituted with 6-Azido- and 6-Aminoflavin Adenine Dinucleotide †Ballou, David P. / Massey, Vincent et al. | 1997
- 15724
-
Inactivation of 4-Oxalocrotonate Tautomerase by 2-Oxo-3-pentynoate †Johnson,, William H. / Czerwinski, Robert M. / Fitzgerald, Michael C. / Whitman, Christian P. et al. | 1997
- 15733
-
Participation of ADP Dissociation in the Rate-Determining Step in cAMP-Dependent Protein Kinase †Zhou, Jie / Adams, Joseph A. et al. | 1997
- 15739
-
Changes in Protonation Associated with Substrate Binding and Cob(I)alamin Formation in Cobalamin-Dependent Methionine Synthase †Jarrett, Joseph T. / Choi, Clara Y. / Matthews, Rowena G. et al. | 1997
- 15749
-
Cobalamin-Dependent Methionine Synthase from Escherichia coli: Involvement of Zinc in Homocysteine Activation †Goulding, Celia W. / Matthews, Rowena G. et al. | 1997
- 15758
-
Glutamate and Aspartate as Proton Shuttles in Mutants of Carbonic Anhydrase †Qian, Minzhang / Tu, Chingkuang / Earnhardt, J. Nicole / Laipis, Philip J. / Silverman, David N. et al. | 1997
- 15765
-
Feed-Back Inhibition of Oxidative Stress by Oxidized Lipid/Amino Acid Reaction Products †Zamora, Rosario / Alaiz, Manuel / Hidalgo, Francisco J. et al. | 1997
- 15772
-
Molecular Mechanism of Regulation of the Pyruvate Dehydrogenase Complex from E. coli †Hennig, Jana / Kern, Gunther / Neef, Holger / Spinka, Michael / Bisswanger, Hans / Hübner, Gerhard et al. | 1997
- 15780
-
Histidine → Carboxamide Ligand Substitutions in the Zinc Binding Site of Carbonic Anhydrase II Alter Metal Coordination Geometry but Retain Catalytic Activity †Lesburg, Charles A. / Huang, Chih-chin / Christianson, David W. / Fierke, Carol A. et al. | 1997
- 15792
-
Evidence for a Functional Role of the Dynamics of Glycine-121 of Escherichia coli Dihydrofolate Reductase Obtained from Kinetic Analysis of a Site-Directed Mutant †Cameron, Craig E. / Benkovic, Stephen J. et al. | 1997
- 15801
-
Modification of Aldose Reductase by S-Nitrosoglutathione †Chandra, Animesh / Srivastava, Sanjay / Petrash, J. Mark / Bhatnagar, Aruni / Srivastava, Satish K. et al. | 1997
- 15810
-
General Acid/Base Catalysis in the Active Site of Escherichia coli Thioredoxin †Chivers, Peter T. / Raines, Ronald T. et al. | 1997
- 15817
-
Steady-State Kinetics and Inhibitor Binding of 3-Deoxy-d-arabino-heptulosonate-7-phosphate Synthase (Tryptophan sensitive) from Escherichia coli †Akowski, James P. / Bauerle, Ronald et al. | 1997
- 15823
-
Use of Thiouredopyrenetrisulfonate Photochemistry for Driving Electron Transfer Reactions in Aqueous Solutions †Kotlyar, Alexander B. / Borovok, Natalia / Hazani, Miron et al. | 1997
- 15828
-
Photoinduced Electron Transfer in Singly Labeled Thiouredopyrenetrisulfonate Cytochrome c Derivatives †Kotlyar, Alexander B. / Borovok, Natalia / Hazani, Miron et al. | 1997
- 15834
-
Cooperativity and Regulation of Scallop Myosin and Myosin Fragments †Kalabokis, Vassilios N. / Szent-Györgyi, Andrew G. et al. | 1997
- 15841
-
Alignment of Fibrillin Molecules in Elastic Microfibrils Is Defined by Transglutaminase-Derived Cross-LinksQian, Rui-Qing / Glanville, Robert W. et al. | 1997
- 15848
-
Probing the Effects of Calcium on GelsolinPope, Brian J. / Gooch, John T. / Weeds, Alan G. et al. | 1997
- 15856
-
Identification of Acetylcholine Receptor Channel-Lining Residues in the M1 Segment of the β-Subunit †Zhang, Hui / Karlin, Arthur et al. | 1997
- 15856
-
Identification of Acetylcholine Receptor Channel-Lining Residues in the M1 Segment of the b-SubunitZhang, Hui et al. | 1997
- 15865
-
Orientation in Lipid Bilayers of a Synthetic Peptide Representing the C-Terminus of the A1 Domain of Shiga Toxin. A Polarized ATR-FTIR Study †Menikh, Abdellah / Saleh, Mazen T. / Gariépy, Jean / Boggs, Joan M. et al. | 1997
- 15873
-
MAP4 Is the in Vivo Substrate for CDC2 Kinase in HeLa Cells: Identification of an M-Phase Specific and a Cell Cycle-Independent Phosphorylation Site in MAP4 †Ookata, Kayoko / Hisanaga, Shin-ichi / Sugita, Minoru / Okuyama, Akira / Murofushi, Hiromu / Kitazawa, Hidefumi / Chari, Sripriya / Bulinski, Jeannette Chloe / Kishimoto, Takeo et al. | 1997
- 15884
-
Covalent Attachment of Ethidium to DNA Results in Enhanced Topoisomerase II-Mediated DNA Cleavage †Marx, Geoffrey / Zhou, Hui / Graves, David E. / Osheroff, Neil et al. | 1997
- 15892
-
Elongation Properties of Vaccinia Virus RNA Polymerase: Pausing, Slippage, 3‘ End Addition, and Termination Site Choice †Deng, Liang / Shuman, Stewart et al. | 1997
- 15900
-
DNA-Binding Properties of the Replication Telomere Protein †Carlson, Deborah L. / Skopp, Rose / Price, Carolyn M. et al. | 1997
- 15909
-
A Novel dCMP Methylase by Engineering Thymidylate Synthase †Agarwalla, Sanjay / LaPorte, Sherry / Liu, Lu / Finer-Moore, Janet / Stroud, Robert M. / Santi, Daniel V. et al. | 1997
- 15918
-
Human Histone Acetyltransferase GCN5 Exists in a Stable Macromolecular Complex Lacking the Adapter ADA2 †Forsberg, E. Camilla / Lam, Lloyd T. / Yang, Xiang-Jaio / Nakatani, Yoshihiro / Bresnick, Emery H. et al. | 1997
- 15925
-
Short-Chain Phosphatidylinositol Conformation and Its Relevance to Phosphatidylinositol-Specific Phospholipase C †Zhou, Chun / Garigapati, Venkata / Roberts, Mary F. et al. | 1997
- 15932
-
Functional Consequence of Mutating Conserved Residues of the Yeast Farnesyl-Protein Transferase β-Subunit Ram1(Dpr1) †Kurth, David D. / Farh, Lynn / Deschenes, Robert J. et al. | 1997
- 15932
-
Functional Consequence of Mutating Conserved Residues of the Yeast Farnesyl-Protein Transferase b-Subunit Ram I (Dpr 1)Kurth, David D. et al. | 1997
- 15940
-
Structural Studies of Detergent-Solubilized and Vesicle-Reconstituted Low-Density Lipoprotein (LDL) Receptor †Saxena, Kumkum / Shipley, G. Graham et al. | 1997
- 15949
-
Suppression of Phospholipase C b,g, and d Families Alters Cell Growth and Phosphatidylinositol 4,5-Bisphosphate LevelsNebigil, Canan G. et al. | 1997
- 15949
-
Suppression of Phospholipase C β, γ, and δ Families Alters Cell Growth and Phosphatidylinositol 4,5-Bisphosphate LevelsNebigil, Canan G. et al. | 1997
- 15949
-
Suppression of Phospholipase C , gamma, and Families Alters Cell Growth and Phosphatidylinositol 4,5-Bisphosphate LevelsNebigil, C. G. et al. | 1997
- 15959
-
Localization of the Heme Binding Region in Soluble Guanylate Cyclase†Zhao, Yunde / Marletta, Michael A. et al. | 1997
- 15965
-
A Targeted Library of Small-Molecule, Tyrosine, and Dual-Specificity Phosphatase Inhibitors Derived from a Rational Core Design and Random Side Chain Variation †Rice, Robert L. / Rusnak, James M. / Yokokawa, Fumiaki / Yokokawa, Shiho / Messner, Donald J. / Boynton, Alton L. / Wipf, Peter / Lazo, John S. et al. | 1997
- 15975
-
Interaction of the Cytoplasmic Tail of CTLA-4 (CD152) with a Clathrin-Associated Protein Is Negatively Regulated by Tyrosine PhosphorylationBradshaw, Jeffrey D. / Lu, Pin / Leytze, Gina / Rodgers, Julie / Schieven, Gary L. / Bennett, Kelly L. / Linsley, Peter S. / Kurtz, Stephen E. et al. | 1997
- 15983
-
Site-Directed Mutagenesis of Rubredoxin Reveals the Molecular Basis of Its Electron Transfer PropertiesKümmerle, Rainer / Zhuang-Jackson, Huayun / Gaillard, Jacques / Moulis, Jean-Marc et al. | 1997
- 15992
-
Role of b87 Thr in the b6 Val Acceptor Site during Deoxy Hb S PolymerizationReddy, Lattupally R. et al. | 1997
- 15992
-
Role of β87 Thr in the β6 Val Acceptor Site during Deoxy Hb S Polymerization †Reddy, Lattupally R. / Reddy, Konda S. / Surrey, Saul / Adachi, Kazuhiko et al. | 1997
- 15999
-
Metal-Catalyzed Oxidation and Mutagenesis Studies on the Iron(II) Binding Site of 1-Aminocyclopropane-1-carboxylate Oxidase †Zhang, Zhihong / Barlow, John N. / Baldwin, Jack E. / Schofield, Christopher J. et al. | 1997
- 16008
-
Mutagenesis of Some Positive and Negative Residues Occurring in Repeat Triad Residues in the ADP/ATP Carrier from Yeast †Müller, Veronika / Heidkämper, Dörthe / Nelson, David R. / Klingenberg, Martin et al. | 1997
- 16019
-
Site-Directed Mutagenesis of the Active Site Glutamate in Human Matrilysin: Investigation of Its Role in Catalysis †Cha, Jaeho / Auld, David S. et al. | 1997