Biological activities of two cola beverages and caffeine: Toxicity, DNA protecting effects, tumor grow inhibition and lifespan increase (Englisch)
- Neue Suche nach: Mateo-Fernandez, M.
- Neue Suche nach: Almagro-Berlanga, R.
- Neue Suche nach: Moreno-Ariza, V.
- Neue Suche nach: Merinas-Amo, R.
- Neue Suche nach: Alonso-Moraga, A.
- Neue Suche nach: Merinas-Amo, T.
- Neue Suche nach: Mateo-Fernandez, M.
- Neue Suche nach: Almagro-Berlanga, R.
- Neue Suche nach: Moreno-Ariza, V.
- Neue Suche nach: Merinas-Amo, R.
- Neue Suche nach: Alonso-Moraga, A.
- Neue Suche nach: Merinas-Amo, T.
In:
TOXICOLOGY LETTERS
;
229
;
S179
;
2014
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ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:Biological activities of two cola beverages and caffeine: Toxicity, DNA protecting effects, tumor grow inhibition and lifespan increase
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Beteiligte:Mateo-Fernandez, M. ( Autor:in ) / Almagro-Berlanga, R. ( Autor:in ) / Moreno-Ariza, V. ( Autor:in ) / Merinas-Amo, R. ( Autor:in ) / Alonso-Moraga, A. ( Autor:in ) / Merinas-Amo, T. ( Autor:in )
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Erschienen in:TOXICOLOGY LETTERS ; 229 ; S179
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Verlag:
- Neue Suche nach: Elsevier Science B.V., Amsterdam.
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Erscheinungsdatum:01.01.2014
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Format / Umfang:S179
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ISSN:
-
Medientyp:Aufsatz (Zeitschrift)
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Format:Print
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Sprache:Englisch
- Neue Suche nach: 363.179
- Weitere Informationen zu Dewey Decimal Classification
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Klassifikation:
DDC: 363.179 -
Datenquelle:
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Author Index| 2014
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- S69
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Humanized anti-HMGB1 antibody therapy attenuates in vivo acetaminophen-induced liver injuryLea, J. / Lundback, P. / Ottosson, L. / Sharkey, J. / Sowinska, A. / Palmblad, K. / Clarke, J. / Park, B. K. / Andersson, U. / Harris, H. et al. | 2014
- S70
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Aluminium intoxication and beer consumption: Effects in the levels of trace metals in mouse brainGonzalez-Munoz, M. J. / Meseguer, I. / Mateos-Vega, C. J. / Benedi, J. / Sanchez-Muniz, F. J. / Lobo-Bedmar, M. d. / Pena-Fernandez, A. et al. | 2014
- S71
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Ecotoxicological evaluation of selected anticancer drugsLutterbeck, C. / Kern, D. / Machado, E. / Kummerer, K. et al. | 2014
- S72
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Interactions of steviol with selected efflux transporters and their impact on cytotoxicity of trimethoprim and dipyridamolMandikova, J. et al. | 2014
- S73
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A cellular model to study acetaminophen-induced hepatotoxicity in the context of nonalcoholic fatty liver diseaseMichaut, A. / Moreau, C. / Robin, M. A. / Fromenty, B. et al. | 2014
- S74
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Susceptibility of lung epithelial cells to alkylating genotoxic insultNagy, K. / Adany, R. / Szucs, S. / Adam, B. et al. | 2014
- S75
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Bromodomain and extraterminal (BET) domain inhibitors induce a loss of intestinal stem cells and villous atrophyWagoner, M. / Kelsal, J. / Hattersley, M. / Hickling, K. / Pederson, J. / Harris, J. / Keirstead, N. / Heathcote, D. / Newham, P. et al. | 2014
- S76
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Multiple modes of chemokine regulation by nitro-PAHs in bronchial epithelial cellsOvrevik, J. / Lag, M. / Refsnes, M. / Schwarze, P. / Holme, J. A. et al. | 2014
- S77
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Evaluation of angiotensin-converting enzyme inhibition by LMRBPP9, a synthetic bradykinin-potentiating peptide from Lachesis muta rhombeata venomPinheiro-Junior, E. / Boldrini-Franca, J. / Santos-Filho, N. / Cilli, E. / Arantes, E. et al. | 2014
- S78
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Hexachlorobenzene exposure enhances COX-2 expression and metalloprotease activities in human endometrial stromal cellsChiappini, F. / Baston, J. I. / Vaccarezza, A. / Singla, J. J. / Pontillo, C. / Miret, N. / Farina, M. / Meresman, G. / Randi, A. et al. | 2014
- S80
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Heterologous production of RBP-SP, a serine protease from Bothrops pauloensis expressed in Pichia pastoris system and its interference on hemostasisRodrigues, R. S. / Franca, J. B. / Silva, L. K. / Gomes, M. S. / de Souza, D. L. / Silva, F. H. / Yoneyama, K. A. / de Melo Rodrigues, V. / Arantes, E. C. et al. | 2014
- S81
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The role of global histone modifications in Fumonisin B1-induced toxicitySancak, D. / Ozden, S. et al. | 2014
- S83
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Complex susceptibility factors suggest new mechanisms of disruption of murine hepatic haem synthesis by chemicals in association with ironRobinson, S. W. / Davies, R. / Vagany, V. / Smith, A. G. et al. | 2014
- S84
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Investigating the mechanism of toxicity of a HER-2 tyrosine kinase inhibitor in human embryonic stem cell derived cardiomyocytes (HESC-CMS)Stephenson, Z. / Stoneley, M. / Thomas, N. / Willis, A. et al. | 2014
- S85
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Possible involvement of the aryl hydrocarbon receptor in dioxin-produced damage to the pituitary-gonad axis: A study using mouse strains differently sensitive to dioxinTakeda, T. / Taura, J. / Hattori, Y. / Ishii, Y. / Yamada, H. et al. | 2014
- S86
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Combined in vitro cellular models and high content screening to investigate metabolism-mediated hepatotoxicityWalker, P. / Bauch, C. / Woodhouse, H. / Bevan, S. et al. | 2014
- S87
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Hydroquinone inhibited the differentiation of HL-60 cells through MIRNA-146A mediationYuan, W. X. / Jiang, Y. P. / Wei, Q. / Sun, Q. / Xie, C. J. / Qin, F. / Chen, Y. C. / Zeng, X. W. / Lv, H. X. / Zhang, X. J. et al. | 2014
- S88
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Glucosinolate hydrolysis products of cruciferous vegetables inhibit cytochrome P450 1A activity and mediate oxidative stressKadir, N. H. / Rossiter, J. T. / Gooderham, N. et al. | 2014
- S89
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Non-clinical safety assessment of gadoteric acid (Dotarem) in the neonatal and juvenile ratBourrinet, P. / Giorgi, H. / Bruffaux, J. P. / Ammerman, J. / Fretellier, N. / Corot, C. et al. | 2014
- S90
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SCYX-7158: Reproductive toxicity studiesGiannotti, E. / Longo, M. / Messina, M. / Ghiglieri, A. / Launay, D. et al. | 2014
- S91
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A case of anticholinergic poisoning by decorative household plantNgo, A. / Wei, L. S. et al. | 2014
- S95
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Magnitudes of biomarker reductions in response to controlled reductions in cigarettes smoked per day: A one-week clinical confinement studyTheophilus, E. / Coggins, C. / Chen, P. / Schmidt, E. / Borgerding, M. et al. | 2014
- S96
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QT prolongation in poisoning: Sources of measurement error and effects of treatmentMcCrae, J. / Veiraiah, A. / Webb, D. / Pettie, J. / Dow, M. et al. | 2014
- S97
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Comparative assessment of protein carbonyls in biological samplesPurdel, N. C. / Dima, I. / Margina, D. / Gradinaru, D. / Ilie, M. et al. | 2014
- S98
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Diagnosis challenge: A coincidence between benzodiazepine intoxication and prion diseaseMacovei, R. / Tincu, R. / Ghiorghiu, Z. et al. | 2014
- S99
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Metabolomics and miRNA biomarkers of paracetamol overdose in rodents and childrenBeger, R. / Yang, X. / Pence, L. / Sun, J. / Schnackenberg, L. / Salminen, W. / Shi, Q. / Greenhaw, J. / Gill, P. / Bhattacharyya, S. et al. | 2014
- S100
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Cytotoxicity evaluation of l-amino acid oxidase from Calloselasma rhodostoma in breast cancer cells MCF-7 and SK-BR-3Bianchini, F. / Burin, S. / Costa, T. / Ghisla, S. / Castro, F. / Vilela, S. / Torqueti, M. et al. | 2014
- S101
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Protective effects of selenium compounds in the toxicity of mercury over the thioredoxin system in neuroblastoma cellsGuerra, I. / Branco, V. / Rodrigues, J. / Carvalho, C. et al. | 2014
- S102
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Assessing potential herb-drug interactions (HDIS): Need for a common framework approachRoe, A. / Paine, M. / Mahony, C. et al. | 2014
- S103
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Exposure and risk assessment of volatile organic compound (benzene, toluene, ethylbenzene, and xylene) from industrial productsGwak, H. M. / Shin, M. k. / Park, H. J. / Lee, J. D. / Kim, J. Y. / Hyeon, J. H. / Um, Y. M. / Lee, B. M. et al. | 2014
- S104
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Human risk assessment of endocrine disrupting chemicals associated ingredients of household plastic containersLee, B. M. / Kim, J. Y. / Chung, B. Y. / Shin, M. k. / Park, H. J. / Lee, J. D. / Gwak, H. M. / Hyeon, J. H. / Um, Y. M. / Son, J. Y. et al. | 2014
- S105
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Effect of chronic exposure to prometryne on red swamp crayfish (Procambarus clarkii)Stara, A. / Kouba, A. / Velisek, J. et al. | 2014
- S106
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Trace elements in undiagnosed type 2 diabetes mellitus (HUNT3)Falkmo, A. / Simic, A. / Olav, A. B. / Richard, R. P. / Kristian, M. / Tore, S. / Peder, F. T. et al. | 2014
- S107
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Investigation of the effect of boric acid on lead and cadmium induced genotoxicityUstundag, A. / Behm, C. / Follmann, W. / Duydu, Y. / Degen, G. et al. | 2014
- S108
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Gene expression profiling of cultured human melanocytes exposed to carbaryl and solar radiationFerrucio, B. / Fannin, R. / Liu, L. / Gerrish, K. / Maria-Engler, S. / Paules, R. / Berlanga, S. et al. | 2014
- S110
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The concept of human exposure-based toxicity testing for agrochemicalsTerry, C. / Whyte, A. / Billington, R. et al. | 2014
- S111
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Mutait, a new genetic toxicology portal and its applications in human health risk assessmentAvancini, D. / Johnson, G. / Menzies, G. / Sullivan, N. / Brancale, A. / Lewis, P. et al. | 2014
- S112
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Mutagenicity of the organic and water-soluble air particulate matter extracts from three different locations in Sao Paulo, Brazil - Developing a strategy to be used routinely in air quality monitoring programsPalacio, I. C. / Lopes, C. F. / Franklin, R. L. / Souza, C. A. / Barros, S. B. / Roubicek, D. A. et al. | 2014
- S113
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Global cross-company data-sharing on the use of recovery animals for human safety assessmentSewell, F. / Chapman, K. et al. | 2014
- S114
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The progestin levonorgestrel affects hypothalamus-pituitary-gonad axis in pubertal roach (Rutilus rutilus)Kroupova, H. K. / Trubiroha, A. / Lorenz, C. / Contardo-Jara, V. / Lutz, I. / Grabic, R. / Kocour, M. / Kloas, W. et al. | 2014
- S117
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Detection of genotoxicity and toxicity of wastewater treatment plant (WTP) effluents after pretreatment with ferrate (VI)Malachova, K. / Sezimova, H. / Rozinek, R. et al. | 2014
- S118
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Route to route extrapolation factors for regulatory risk assessment-A probabilistic approachSchroeder, K. / Hoffmann-Doerr, S. / Mangelsdorf, I. / Escher, S. et al. | 2014
- S119
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Micronutrient exposure modelling: To build a refined safety assessment for micronutrientsO'Keeffe, L. / Pigat, S. et al. | 2014
- S123
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Current modeling practice may lead to falsely high benchmark dose estimatesOberg, M. / Ringblom, J. / Johanson, G. et al. | 2014
- S124
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GreenScreen for Safer Chemicals, as a support tool for the EU reach regulation: Identifying chemicals of very high concern (SVHC) and safer alternativesZachary, M. / Gebhart, A. M. / Whittaker, M. et al. | 2014
- S125
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A novel toolkit for appraising the methodological quality of literature reviews in the toxicological sciencesWhaley, P. / Halsall, C. et al. | 2014
- S127
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Risk assessment approach for e-cigarette flavoursCostigan, S. / Lang, B. / Collard, J. et al. | 2014
- S129
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Reconstituted human airway epithelium 3D-model, a suitable in vitro model, to assess airborne pollutants impacts on human respiratory tractBardet, G. / Achard, S. / Momas, I. / Seta, N. et al. | 2014
- S130
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Investigation of the action of ethiprole in non-target organisms using Oreochromis niloticus as a bioindicatorGuedes, T. / Fontanetti, C. et al. | 2014
- S131
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Risk assessment at pesticides effect with food-stuffRakitskii, V. et al. | 2014
- S132
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Identification of the most common pathogens formed by environmental fungus toxins in human's eyeEbadollahinatanzi, A. / Arabrahmatipour, G. / Tabatabaei, S. A. et al. | 2014
- S134
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PON-1 activity as a protective player in nevirapine hepatotoxicity: Data comparison in 2D and 3D cell culturesMarinho, A. T. / Dias, C. G. / Pinheiro, P. F. / Antunes, A. M. / Marques, M. M. / Monteiro, E. C. / Miranda, J. P. / Pereira, S. A. et al. | 2014
- S135
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In-house validation and technology transfer of the GARD assay for prediction of sensitizing compoundsForreryd, A. / Johansson, H. / Rydnert, F. / Albrekt, A. S. / Borrebaeck, C. / Lindstedt, M. et al. | 2014
- S136
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Lactobacillus sp. colonized 3D human vaginal mucosa: A promising model to assess the tolerance of intimate hygiene cosmeticsLandolfi, C. / Devastato, C. / Meloni, M. / Fontaine, T. / Resconi, A. / de Joannon, A. C. / Durando, L. et al. | 2014
- S141
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Collagen hydrogel matrices for primary hepatocyte cultureAgbekoh, P. E. / Henderson, C. / Riches, P. E. / Grant, M. H. et al. | 2014
- S142
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Three-dimensional (3D) human hepatocyte spheroids as model for prediction of DILI: Effect of viral infection and TNFa on function and drug toxicityMoro, S. / Persson, A. / Bell, C. / Puigvert, L. F. / Hendriks, D. / Sim, S. / Ingelman-Sundberg, M. et al. | 2014
- S143
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In vitro human alveolar tissue model for pulmonary toxicology applicationsHayden, P. J. / Jackson, G. R. / Mankus, C. / Letasiova, S. / Ayehunie, S. et al. | 2014
- S146
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Urinary reference concentrations of biomarker of oxidative DNA damage: 8-Oxo-7,8-dihydro-2'-deoxyguanosine in females from polish populationBledzka, D. / Mikolajewska, K. / Gresner, P. / Gromadzinska, J. / Wasowicz, W. et al. | 2014
- S147
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Mode of action and lack of human health relevance of increased hepatocellular adenoma in male CD1 mice treated with cyproconazoleCowie, D. / Green, R. / Currie, R. / Barnes, E. / Peffer, R. et al. | 2014
- S148
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The aryl hydrocarbon receptor (AHR) is a new target for prevention and treatment of cutaneous squamous cell carcinomasHaarmann-Stemmann, T. / Frauenstein, K. / Tigges, J. / Fischer, K. / Esser, C. / Krutmann, J. et al. | 2014
- S149
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Modulation of the AhR-dependent gene expression in human lung adenocarcinoma A549 cells by abundant airborne carcinogenic PAHsHruba, E. / Krckova, S. / Vondracek, J. / Machala, M. et al. | 2014
- S150
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Interest of immunohistochemistry in the evaluation of tumorigenic potential of advanced therapy medicinal productsWeidmann, K. / Leoni, A. L. / Weber, K. et al. | 2014
- S153
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Activation of TGFb-1 signaling pathways in human breast cancer cell line MDA-MB-231 induced by hexachlorobenzene pesticideMiret, N. / Pontillo, C. / Chiappini, F. / Alvarez, L. / de Pisarev, D. K. / Ventura, C. / Cocca, C. / Randi, A. et al. | 2014
- S160
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Modelling the effect of DMSA chelation therapy in patients intoxicated by leadvan Eijkeren, J. C. / Olie, J. D. / Bradberry, S. M. / Vale, J. A. / de Vries, I. / Clewell, H. J. / Meulenbelt, J. / Hunault, C. C. et al. | 2014
- S161
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Drug spider: Pinpointing genes responsible for common side effect produced by several drugsLandre, V. / Knight, R. / Melino, G. / Antonov, A. et al. | 2014
- S162
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Integrating computational modelling of receptor binding into mechanistically based risk assessment for endocrine disruptorsMellor, C. / Cronin, M. / Evenseth, L. / sylte, I. / kristiansen, K. / Tollefsen, K. E. et al. | 2014
- S163
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Using mode of action framework in prediction of skin toxicityRakic, B. / Potkrajac, D. M. / Price, A. / Apic, G. / Russell, R. B. et al. | 2014
- S164
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A text-mining approach for chemical risk assessment and cancer researchSilins, I. / Korhonen, A. / Guo, Y. / Stenius, U. et al. | 2014
- S165
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Preclinical safety assessment of a RANKL blocker, RPH-203 following subcutaneous (SC) administration of repeated doses in the Cynomolgus monkeySamsonov, M. / Archuadze, S. / Oshodi, T. / Dwivedi, P. et al. | 2014
- S166
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Oral voluntary ingestion as a stress free alternative to orogastric gavage: The example of losartan chronic administrationDiogo, L. / Faustino, I. / Afonso, R. / Pereira, S. / Monteiro, E. / Santos, A. et al. | 2014
- S167
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In vitro evaluation of reactivating efficacy of newly developed oximes for preparation of ''pseudocatalytic scavenger'' based on butyrylcholinesteraseKrenkova, Z. / Musilek, K. / Kuca, K. / Jun, D. et al. | 2014
- S168
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A standardized approach for in vivo photosafety testingvan Huygevoort, T. / Latour, J. / Emmen, H. et al. | 2014
- S169
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Protective effects of quercetin against HGCL2-induced nephrotoxicity in sprague-dawley ratsKim, K. S. / Son, J. Y. / Kang, Y. J. / Kim, H. S. et al. | 2014
- S172
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Cytotoxicity and morphological study of an extract from the allium essential oil potentially used in active packagingLlana-Ruiz-Cabello, M. / Gutierrez-Praena, D. / Puerto, M. / Pichardo, S. / Moreno, F. J. / Banos, A. / Nunez, C. / Guillamon, E. / Camean, A. M. et al. | 2014
- S174
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Detection of mutagenic activity of novel modified clays intended to a nanocomposite material by the Ames testMaisanaba, S. / Prieto, A. I. / Pichardo, S. / Jorda-Beneyto, M. / Camean, A. M. / Jos, A. et al. | 2014
- S175
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Evaluation of the oxidative response in Wistar rats exposed for 90 days to an extract of a nanocomposite materialMaisanaba, S. / Gutierrez-Praena, D. / Puerto, M. / Ruiz-Cabello, M. L. / Pichardo, S. / Jorda-Beneyto, M. / Jos, A. et al. | 2014
- S177
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Multi-mycotoxin analysis in North African semolina samples using a modified QuEChERS-based extraction procedure and HPLC-MS/MSManyes, L. / Toffa, D. D. / Escriva, L. / Zinedine, A. / Fernandez, M. et al. | 2014
- S178
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In vitro evaluation of the genotoxic potential of plant food supplements (PFS) containing alkenylbenzene compoundsMarabini, L. / Galli, C. L. / van den Berg, S. J. / Marinovich, M. et al. | 2014
- S179
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In vivo and in vitro toxicological and biological activities of alpha-acid humulone, isoxanthohumol and stout beerMerinas-Amo, T. / Martinez-Jurado, M. / Merinas-Amo, R. / Mateo-Fenandez, M. / Alonso-Moraga, A. et al. | 2014
- S181
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Validation of a reporter gene assay for the detection of synthetic glucocorticoids in calf urine samplesPitardi, D. / Meloni, D. / Olivo, F. / Cavarretta, M. / Loprevite, D. / Richelmi, G. B. / Capra, P. / Gili, M. / Ingravalle, F. / Pezzolato, M. et al. | 2014
- S182
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Effect of soyasaponin I against cytotoxicity and oxidative stress induced by alternariol in Caco-2 cellsVila-Donat, P. / Fernandez-Blanco, C. / Sagratini, G. / Font, G. / Ruiz, M. J. et al. | 2014
- S183
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Glyoxal shows tumour promoting activity in the multiple intestinal neoplasia (Min) mouse modelSvendsen, C. / Saether, A. H. / Alexander, J. / Husoy, T. et al. | 2014
- S184
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Trace elements in organic and conventional rice commercialized in ChinaChen, J. / Wang, X. / Zhou, Y. / Liu, X. et al. | 2014
- S185
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Evaluation of the anti- inflammatory, analgesic and anti-ulcerogenic potentials of achillea fragrantissima (FORSSK.)Abdel-Rahman, R. F. / Khataibah, M. H. / Alqasoumi, S. I. / El-Desoky, A. H. / Soliman, G. A. / Hegazy, M. E. et al. | 2014
- S186
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Single particle tracking method for the analysis of intracellular movement of the silica nanoparticlesAoyama, M. / Yoshioka, Y. / Arai, Y. / Ishimoto, R. / Tsunoda, S. i. / Higashisaka, K. / Nagai, T. / Tsutsumi, Y. et al. | 2014
- S188
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Cytotoxicity of gold and silver nanoparticles in the Caco-2 human intestinal epithelial cell lineFernandes, M. / Pereira, C. / Gajo, K. / Pereira, E. / Carmo, H. / Bastos, M. d. / Fraga, S. et al. | 2014
- S190
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New biomarker: Novel, relevant, rapid, sensitive non-invasive electrophysiology technique and the potential role of P-glycoprotein in modulating silver nanoparticle toxicity in earthworms and aquatic oligochaetesGooneratne, R. / Demizieux, N. / Wellby, M. et al. | 2014
- S191
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In vitro models as physiologically relevant tools to investigate pulmonary and intestinal toxicityKlein, S. G. / Georgantzopoulou, A. / Serchi, T. / Cambier, S. / Leclercq, C. C. / Renaut, J. / Kruszewski, M. / Lankoff, A. / Lentzen, E. / Grysan, P. et al. | 2014
- S192
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Critical role of interleukin 1 for the initiation and resolution of pulmonary inflammation induced by carbon nanomaterialsHabel, N. C. / Kutschke, D. / Eickelberg, O. / Meiners, S. / Stoeger, T. et al. | 2014
- S194
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Charge and size-dependent toxicity of silver nanoparticles to yeast cellsKasemets, K. / Suppi, S. / Mantecca, P. / Kahru, A. et al. | 2014
- S194
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The role of coating materials and zeta potential in iron oxide nanoparticle translocation in human intestinal cellsLichtenstein, D. / Bertin, A. / Fiedler, D. / Horzowski, S. / Palavinskas, R. / Niemann, B. / Thunemann, A. / Lampen, A. et al. | 2014
- S195
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Expression profiling analysis of microRNAs in RAW264.7 cells exposed to titanium dioxide nanoparticlesLiang, G. / Fu, Y. / Zhang, Y. / Ma, S. / Sui, J. / Yin, L. / Pu, Y. et al. | 2014
- S197
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Action of polymeric nanoparticles on cell viability, gene expression and internalization as a function of cell lineSafar, R. / Ronzani, C. / Diab, R. / Le Faou, A. / Rihn, B. H. / Joubert, O. et al. | 2014
- S198
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Epigenetic alterations induced by nanoparticlesTabish, A. / Poels, K. / Baccarelli, A. / Hoet, P. / luyts, K. / Godderis, L. et al. | 2014
- S199
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Effects of single and repeated oral administration of mesoporous silica nanoparticles in Wistar ratsTzankova, V. / Vitcheva, V. et al. | 2014
- S204
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Effect of low level of exposure to deltamethrin on infection susceptibility in miceRehman, H. / Raisuddin, S. et al. | 2014
- S205
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Measuring T cell dependent and independent antibody responses (TDAR/TIAR) in the cynomolgus macaque: Abatacept (CTLA4-Ig) and methotrexate lead to immunosuppression in a TDAR but not TIAR responseConey, L. / Harper, K. / Bannish, G. et al. | 2014
- S207
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Glycophorin a blocks the response to TGN1412 in whole blood cytokine release assaysVessillier, S. / Eastwood, D. / Fox, B. / Swaminathan, S. / Sathish, J. / Thorpe, S. / Thorpe, R. / Stebbings, R. et al. | 2014
- S208
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The effects of BDE-209 on peripheral leukocyte counts in subacutely exposed Wistar ratsMilovanovic, V. / Buha, A. / Curcic, M. / Vucinic, S. / Jacevic, V. / Jankovic, S. / Antonijevic, B. et al. | 2014
- S209
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The genetic toxicity of complex mixtures of polycyclic aromatic hydrocarbons: Employing the in vivo Muta(TM)Mouse TGR assay to evaluate the assumption of response additivityLong, A. S. / Lemieux, C. L. / White, P. A. et al. | 2014
- S210
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Suitability of histopathology as an additional endpoint to the isolated chicken eye test for classification of non-extreme ph detergent and cleaning productsCazelle, E. / Eskes, C. / Hermann, M. / Jones, P. / McNamee, P. / Prinsen, M. / Taylor, H. / Wijnands, M. et al. | 2014
- S212
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Toxicological effect of single contaminants and contaminant mixtures associated with plant ingredients in novel salmon feedsSofteland, L. / Kirwan, J. A. / Hori, T. S. / Storseth, T. R. / Sommer, U. / Berntssen, M. H. / Viant, M. R. / Rise, M. L. / Waagbo, R. / Torstensen, B. E. et al. | 2014
- S213
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In vitro cytotoxic effects, antioxidant capacity and phytochemical evaluations of extracts of Clausena anisata, Peltophorum africanuum and Zanthoxylum capenseAdebayo, S. / Ndzoyem, J. P. / Shai, J. / Gulumain, M. / Eloff, K. et al. | 2014
- S214
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Effects of single or repeated Yukmijihwang-tang administration, a polyherbal formula, on pharmacokinetics of metformin in ratsPark, S. J. / Kang, S. B. / Sohn, H. S. / Kang, S. J. / Lee, E. K. / Lee, J. E. / Song, C. H. / Lee, Y. J. / Ku, S. K. et al. | 2014
- S215
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Simple estimate of the influence of competitive inhibition on PBTK based risk assessmentReffstrup, T. K. / Petersen, A. / Nielsen, E. / Jonsdottir, S. O. et al. | 2014
- S216
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Toluene diisocyanate effect on A549 cells in the expression of c-Myc, NFkappaB and target genesPosadas-Mondragon, A. / Angulo-Rojo, C. / Rios-Perez, A. / Albores, A. / Aguilar-Faisal, L. / Alcantara-Farfan, V. / Neri-Bazan, R. / Vargas-Ramirez, A. / Lopez-Bayghen, E. / Ramirez, L. et al. | 2014
- S217
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A fundamental role for non-canonical small RNAs in DNA repairHawley, B. / Lu, W. T. / Malewicz, M. / Bushell, M. et al. | 2014
- S218
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Integrating toxicokinetics into the human health risk assessment process for agrochemicals: Halauxifen-methylTerry, C. / Murphy, L. / McCoy, A. / Aggarwal, M. / McFadden, L. / Rasoulpour, R. / Rick, D. / Bartels, M. / Billington, R. et al. | 2014
- S219
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Incorporation of cardiovascular safety pharmacology endpoints in toxicology studies in the minipigMcPhie, G. / Melliti, K. / Purbrick, S. / Butler, D. / Meecham, K. et al. | 2014
- S220
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N-methylcarbamoyl amino acids in the urine of rats exposed to N,N-dimethylformamide and N-methylformamideMraz, J. / Linhart, I. / Hanzlikova, I. / Duskova, S. / Dabrowska, L. / Chrastecka, H. et al. | 2014
- S223
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Further progress on steps to reduce animal numbers used on regulatory toxicology studies utilising microsampling and sample-sparing techniquesLawrence, R. / Coleman, D. / Mitchell, D. et al. | 2014
- S224
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Aflatoxins: Occurrence in animal feeds and milk from dairy farms in Aguascalientes, MexicoOrtiz-Martinez, R. / Luna-Lopez, M. C. / Valdivia-Flores, A. / Quezada-Tristan, T. et al. | 2014
- S225
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Pre-clinical and in vitro epigenetic studies on the genome-wide impact of high-consuming beveragesMerinas-Amo, R. / Mateo-Fernandez, M. / Ruiz-Calzado, R. / Martinez-Jurado, M. / Anaya, G. / Morales-Ruiz, T. / Garcia-Ortiz, M. V. / Membrillo, A. / Alonso-Moraga, A. / Merinas-Amo, T. et al. | 2014
- S226
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Pharmacological modulation of behavioral and biochemical effects resembling Huntington's disease utilizing sildenafil and RO-20-1724Rani, V. et al. | 2014
- S227
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Hair and urine testing to assess organophosphorus pesticides burden in sprayers and rural residents during a spraying period: Application in residents of GreeceKokkinaki, A. / Kokkinakis, M. / Kavvalakis, M. / Tzatzarakis, M. / Maravgakis, G. / Renieri, E. / Fragkiadakis, G. / Babatsikou, F. / Tsatsakis, A. et al. | 2014
- S232
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Percellome toxicogenomicsKanno, J. / Aisaki, K. i. / Kitajima, S. et al. | 2014
- S236
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Associations between DNA double strand breaks and N7-methyldeoxyguanosine in human sperm and fertility outcomesAltakroni, B. / Stocks, J. / Brison, D. / Povey, A. et al. | 2014
- S237
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Target organ toxicities in studies conducted to support first time in man dosing: An analysis across species & therapy areasLees, D. / Horner, S. / Robinson, S. / Ryan, D. / Callander, R. / Roberts, R. et al. | 2014
- S238
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Lysine acetylsalicylate improves the safety of paraquat formulation in rats by increasing its elimination and preventing lung and kidney injuryBaltazar, M. T. / Dinis-Oliveira, R. / de Lourdes Bastos, M. / Duarte, J. A. / Carvalho, F. et al. | 2014
- S239
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An integrated characterisation of serological, pathological and functional events in doxorubicin-induced cardiotoxicityCove-Smith, L. / Woodhouse, N. / Hargreaves, A. / Price, S. / Marsden, M. / Betts, C. / Brocklehurst, S. / Backen, A. / Radford, J. / Roberts, R. et al. | 2014
- S240
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Sex differences in hepatic and intestinal contributions for nevirapine biotransformationPinheiro, P. F. / Marinho, A. T. / Antunes, A. M. / Marques, M. M. / Castro, M. F. / Pereira, S. A. / Miranda, J. P. et al. | 2014
- S242
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Application of a human renal proximal tubule cell line, RPTEC/TERT1, for chemical safety assessmentAschauer, L. / Wilmes, A. / Limonciel, A. / Leonard, M. O. / Pfaller, W. / Jennings, P. et al. | 2014
- S243
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Effects of ferulic acid on oxidative stress parameters in livers and kidneys of Wistar albino ratsBacanli, M. / Aydin, S. / Taner, G. / Goktas, H. G. / Sahin, T. / Basaran, A. / Basaran, N. et al. | 2014
- S244
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Comparison of acetaminophen toxicity in rat and mouse hepatocytes in vitroKucera, O. / Rousar, T. / Mezera, V. / Cervinkova, Z. et al. | 2014
- S246
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Comparison of acetaminophen toxicity in primary hepatocytes isolated from transgenic mice with different apolipoprotein E allelesMezera, V. / Kucera, O. / Moravcova, A. / Peterova, E. / Rychtrmoc, D. / Sobotka, O. / Cervinkova, Z. et al. | 2014
- S249
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Reactive environmental metabolite, 1,2-diacetylbenzene, induces cognitive impairment via Tau hyperphosphorylationKim, M. S. / Kang, S. W. / Baek, K. H. et al. | 2014
- S250
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Animal poisoning data from poison control centre: A tool for risk communicationCaloni, F. / Cortinovis, C. / Pizzo, F. / Rivolta, M. / Davanzo, F. et al. | 2014
- S251
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Comparison of GHS classification of CMR substances in EU and JapanMorita, T. et al. | 2014
- v
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Contents| 2014
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Evolution of mode of action/adverse outcome pathway analysesMeek, M. E. et al. | 2014
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Investigation of urinary microRNAs associated with segment specific injury to the nephronGautier, J. C. et al. | 2014
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Use of ''omics'' information in risk assessment of new food risks: Proteomic investigations into mechanism of liver, kidney, and testicular toxicity induced by 3-MCPD and its dipalmitate ester in ratsLampen, A. et al. | 2014
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Integrating in vitro and in vivo data: Lessons learned from the ACROPOLIS projectMoretto, A. / Menegola, E. et al. | 2014
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Specific challenges for hazard characterisation of nanomaterials/nanoforms under reachLe Curieux, F. et al. | 2014
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Low-dose effects: Experimental challenges for endocrine disruptionPiersma, A. et al. | 2014
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Evaluation of a chemical genetic approach to determine GPCR functionBrooke, S. M. / Tobin, A. et al. | 2014
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The effect of additional noradrenergic and serotonergic depletion on lateralised choice reaction time task in rats with nigral 6-OHDA lesionsDemirbugen, M. / Lindgren, H. S. / Lane, E. L. et al. | 2014
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Elucidating adverse outcome pathways with phenotypic data from primary human cell systemsBerg, E. / Polokoff, M. / O'Mahony, A. / Yang, J. et al. | 2014
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Characterisation of the gastrointestinal and bone marrow toxicities associated with Irinotecan treatment after a single intra peritoneal dose in the Han Wistar ratCronin, A. / Barnes, J. / Derbyshire, N. / Heathcote, D. / Pedersen, J. et al. | 2014
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Characterisation of the hepatic effects of pregnenolone 16 alpha-carbonitrile (PCN) in pregnane X receptor (PXR, NR1I2) knockout (KO) ratsVardy, A. / Chamberlain, M. / Foster, J. / Elcombe, C. et al. | 2014
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Toxicity of nanofilm spray products assessed by in vivo and in vitro techniquesHansen, J. S. / Sorli, J. B. / Norgaard, A. W. / Larsen, S. T. et al. | 2014
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Combined effects of okadaic acid and yessotoxin - The role of human CYP metabolism and hepatic transcription factorsKolrep, F. / Bartossek, T. / Glombik, S. / Hessel, S. / Lampen, A. et al. | 2014
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The effects of the herbicide diuron in MCF-7 and Bewo cellsHuovinen, M. / Loikkanen, J. / Naarala, J. / Vahakangas, K. et al. | 2014
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Effects of moniliformin on gene expression of pyruvate dehydrogenase, pyruvate carboxylase and a-ketoglutarate in rat primary hepatocytesJonsson, M. / Jestoi, M. / Koivisto, P. / Nathanail, A. / Peltonen, K. et al. | 2014
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Comparison of acetaminophen hepatotoxicity and nephrotoxicity in vitroRousar, T. / Vrbova, M. / Kucera, O. / Nydlova, E. / Cervinkova, Z. et al. | 2014
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Molecular evidence that metabolic reprogramming contributes to cell survival and chemoresistance in malignant mesotheliomaSun, X. M. / Chernova, T. / Grosso, S. / Murphy, F. A. / Bennett, J. / Nakas, A. / Bushell, M. / Willis, A. E. / Cain, K. / MacFarlane, M. et al. | 2014
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Inhibition of Protein Cinase A reduces the nephrotoxicity of cyclosporineFranca, F. / Tagliati, C. / Chaves, M. et al. | 2014
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Alterations in DNA methylation of Bisphenol A in rat kidney NRK-52E cellsTuzcuoglu, P. / Ozden, S. et al. | 2014
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Adapting animal husbandry for pre-weaning juvenile toxicity studies in the rabbitMarsden, E. / Raynard, A. / Pique, C. / Briffaux, J. P. et al. | 2014
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Neuroblasts disturbances induced by perinatal exposure to glufosinate ammoniumHerzine, A. / Laugeray, A. / Richard, O. / Montecot-Dubourg, C. / Mortaud, S. et al. | 2014
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Nonhuman primate infant anatomic pathology historical background data from pre- and post-natal developmental (EPPND) studiesLalyeva, N. / Oneda, S. / Makori, N. / Watson, R. / Beck, T. / Fukuzaki, K. / Nagata, R. et al. | 2014
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Effects of modulating morphine metabolism on its pharmacological action in guinea pigsOliveira, A. / Pinho, D. / Albino-Teixeira, A. / Medeiros, R. / Dinis-Oliveira, R. / Carvalho, F. et al. | 2014
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Suicide attempt by pharmaceutical ingestion in a tertiary unitTincu, R. / Macovei, R. / Ghiorghiu, Z. et al. | 2014
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Mitochondrial dysfunctions in liver due to environmental drug contaminants and obesityPorceddu, M. / Buron, N. / Fromenty, B. / Borgne-Sanchez, A. et al. | 2014
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The in vitro cytotoxicity of sucralose on fish cell linesKolarova, J. / Grabic, R. / Grabicova, K. / Randak, T. et al. | 2014
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Endocrine disrupting compounds and heavy metals in the amniotic fluid and neurodevelopment disorders: A case-control studyLong, M. / Kjeldsen, L. / Ghisari, M. / Bossi, R. / Asmund, G. / Bonefeld-Jorgensen, E. C. et al. | 2014
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Volatile organic compounds-Understanding the risks to drinking waterRockett, L. / Gee, R. / Aldous, E. / Benson, V. / Brandon, Y. / Briere, B. / Dee, A. / Rumsby, P. / Shepherd, D. / Turrell, J. et al. | 2014
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Is there a need to conduct an avian inhalation study for my formulation or test article?Moore, S. / Crome, S. et al. | 2014
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ES cell models for studying neurotoxicityPanman, L. / Oosterveen, T. / Dhiraj, D. / Knight, E. et al. | 2014
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Importance of reproducibility demonstration of the bio-engineered tissue models used for in vitro toxicity testing purposesLetasiova, S. / Bachelor, M. / Kandarova, H. / Sebova, K. / Kearney, P. / Klausner, M. et al. | 2014
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Human neural microtissues derived from induced pluripotent stem cells for toxicity testingFluri, D. / Marchan, R. / Moritz, W. / Kopitas, G. / Hengstler, J. G. / Kelm, J. M. / Messner, S. et al. | 2014
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Phenobarbital-mediated tumor promotion in transgenic mice with humanized CAR and PXRBraeuning, A. / Gavrilov, A. / Schwarz, M. et al. | 2014
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Lifetime carcinogenicity studies in the CD-1 mouse: Historical data for survival and neoplasmsForster, R. / Thirion-Delalande, C. / Palate, B. / Le Bigot, J. F. et al. | 2014
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Benzene metabolite hydroquinone induces homologous recombination and single-strand annealing repairYang, X. / Huang, G. / Hou, F. / Yan, J. / Guo, X. / Wang, Q. / Xing, C. et al. | 2014
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Comparison of genotoxic effects of major diesel exhaust components in human alveolar basal epithelial cells (A549)Topinka, J. / Rossner, P. / Stolcpartova, J. / Schmuczerova, J. / Milcova, A. / Hruba, E. / Machala, M. et al. | 2014
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QSAR approach to enhance the prediction coverage and performance of acute toxicity to Daphnia magna with diverse organic compoundsCha, J. Y. / Shin, S. / Kim, K. Y. / No, K. T. et al. | 2014
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Identification of in silico structural alerts for liver steatosis induced by nuclear receptor agonistsMellor, C. / Cronin, M. / Steinmetz, F. et al. | 2014
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Genotoxicity evaluation of a major compound of oregano essential oil by the in vitro micronucleus assayLlana-Ruiz-Cabello, M. / Maisanaba, S. / Prieto, A. I. / Puerto, M. / Pichardo, S. / Camean, A. M. et al. | 2014
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Microarray system for toxicity and bioavailability studies of endocrine disruptors in foodGier, K. / Sauer, U. et al. | 2014
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Genotoxicity evaluation of different clays used in food packaging in Caco-2 cells by the Comet assayMaisanaba, S. / Rubiales, J. / Puerto, M. / Pichardo, S. / Jorda-Beneyto, M. / Aucejo, S. / Jos, A. et al. | 2014
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Cytotoxic effects by combining alternaria and trichotecene mycotoxins in liver hepatocellular carcinoma cellsJuan-Garcia, A. / Konig, S. / Font, G. / Ruiz, M. J. et al. | 2014
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In vitro lung models for testing NPs effects: A case study on zinc oxide toxicityBengalli, R. D. / Gualtieri, M. / Mantecca, P. / Urani, C. / Camatini, M. / Stoger, T. et al. | 2014
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Modulation of erythropoiesis and erythrocytes turnover in mice in response to acid functionalized single walled carbon nanotubes (AF-SWCNTS) treatmentsBhardwaj, N. / Saxena, R. K. et al. | 2014
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The renal effects of a single and low dose of titanium dioxide nanoparticles in adult male ratsEscarcega-Gonzalez, C. E. / Rodriguez-Vazquez, M. L. / Jaramillo-Juarez, F. / De La Cerda-Gonzalez, E. / Ruvalcaba, H. M. et al. | 2014
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Genotoxicity assessment of iron oxide nanoparticles in male Wistar rats after chronic oral treatmentRozgaj, R. / Kasuba, V. / Mladinic, M. / Kopjar, N. / Micek, V. / Zeljezic, D. et al. | 2014
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Cytotoxicity of iron oxide nanoparticles with different coatings on human neuronal cellsCosta, C. / Kilic, G. / Brandao, F. / Bessa, M. J. / Costa, S. / Pasaro, E. / Valdiglesias, V. / Laffon, B. / Teixeira, J. P. et al. | 2014
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An in vitro coculture approach to assess the impact of skin keratinocytes on chemical-induced activation of dendritic cellsHennen, J. / Kinitz, T. / Blomeke, B. et al. | 2014
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CRY1AB protein from MON810 transgenic maize and Bacillus thuringiensis has no clear adjuvanticity after intranasal exposureAndreassen, M. / Bohn, T. / Wikmark, O. G. / Van den Berg, J. / Lovik, M. / Traavik, T. / Nygaard, U. C. et al. | 2014
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VUSE electronic cigarette aerosol chemistry and cytotoxicityTheophilus, E. / Potts, R. / Fowler, K. / Fields, W. / Bombick, B. et al. | 2014
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Effects of Gamiondam-tang administration, a polyherbal formula, on pharmacokinetics of tamoxifen in ratsPark, S. J. / Park, S. H. / Kwak, M. A. / Kang, S. J. / Lee, E. K. / Lee, J. E. / Song, C. H. / Lee, Y. J. / Ku, S. K. et al. | 2014
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Cellular response of THP-1 cells cultured on the polymer biomaterialsMiyajima-Tabata, A. / Kato, R. / Komoriya, K. / Niimi, S. et al. | 2014
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miRNAs quantification and evaluation of suitable housekeeping genes in the major pre-clinical speciesPearson, N. J. / Rogue, A. / Forster, R. / Floch, E. et al. | 2014
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Assessment of aflatoxin M1 levels in white cheeseOrtiz-Martinez, R. / De Luna-Lopez, M. C. / Valdivia-Flores, A. / Quezada-Tristan, T. et al. | 2014
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Is there a correlation between lymphocyte DNA damage and hair arsenic levels?Soylemez, E. / Kayaalti, Z. / Akyuzlu, D. K. / Soylemezoglu, T. et al. | 2014
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Transcriptome analysis of Tityus serrulatus scorpion venom gland reveals novel toxinsAmorim, F. G. / de Deus Wagatsuma, V. M. / Antonio, D. S. / da Silva Junior, W. A. / Kashima, S. / Arantes, E. C. et al. | 2014
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Integration of high-throughput in vitro assays and human exposure modeling for risk-based chemical safety decisionsThomas, R. et al. | 2014
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EFSA's approach to characterising uncertainty in risk assessmentGermini, A. et al. | 2014
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Regulatory experience with cytokine release testing for monoclonal antibodiesReichmann, G. et al. | 2014
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Quantitative in vitro to in vivo extrapolation of stem cell-based toxicity data to predict developmental toxicity dose levelsLouisse, J. et al. | 2014
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Evaluating developmental toxicity using efficient short tests based in molecular approaches during cell differentiation: The example of chlorpyrifosVilanova, E. / Estevan, C. / Fuster, E. / Del Rio, E. / Sogorb, M. et al. | 2014
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A 3-dimensional human embryonic stem cells-derived model to detect DNT of nanoparticlesKadereit, S. et al. | 2014
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Carcinogenicity of diesel- (DEE) and gasoline-engine exhausts (GEE)Benbrahim-Tallaa, L. / Baan, R. / Grosse, Y. / Lauby-Secretan, B. / Ghissassi, F. E. / Bouvard, V. / Guha, N. / Loomis, D. / Straif, K. et al. | 2014
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Differential effects of ambient diesel carcinogens on inflammation and DNA damage response in cells relevant for lung toxicityLonghin, E. / Ovrevik, J. / Gualtieri, M. / Totlandsdal, A. / Mollerup, S. / Ask, K. / Arlt, V. M. / Schwarze, P. E. / Camatini, M. / Holme, J. A. et al. | 2014
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Assessment of neurotoxicity: The use of biomarkers as complementary measuresBradley, A. et al. | 2014
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Screening of compounds that alter sleep-wake state in zebrafishHolgado, O. / Muriana, A. / Dekeyne, A. / Louis, C. / Alzualde, A. et al. | 2014
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Strategic focus on 3R principles reveals major reductions in the use of animals in pharmaceutical toxicity testingOberg, M. / Tornqvist, E. / Annas, A. / Granath, B. / Jalkesten, E. / Cotgreave, I. et al. | 2014
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Perfluorooctanoic acid induces delayed toxicity in human cells in vitroPeropadre, A. / Freire, P. F. / Martin, J. M. / Hazen, M. J. et al. | 2014
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Reproductive toxicology studies in Japanese Quail: reference dataEsdaile, D. J. / Sipos, K. / Gaty, S. et al. | 2014
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An insight into the mechanisms underlying the hepatotoxicity of cathinone derivativesValente, M. J. / Araujo, A. M. / Carvalho, F. / Bastos, M. d. / de Pinho, P. G. / Carvalho, M. et al. | 2014
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Structure-dependent activation and inhibition of nuclear receptors by hepatotoxic pyrrolizidine alkaloidsLuckert, C. / Hessel, S. / Lampen, A. et al. | 2014
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Mechanisms of pulmonary toxicity developed at low and high doses of dextran-coated magnetite nanoparticlesRadu, M. / Gheorghiu, A. / Predoi, D. / Hermenean, A. / Ardelean, A. / Dinischiotu, A. et al. | 2014
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Effect of glutathione-S-transferase omega 2 N142D gene polymorphism on urinary mercury levels in school-aged childrenAkyuzlu, D. K. / Kayaalti, Z. / Soylemez, E. / Bal, C. / Ozdemir, F. / Tutkun, E. / Soylemezoglu, T. et al. | 2014
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Mean platelet volume level in chromium exposed workersHocaoglu, A. / Bal, C. / Celik, H. T. / Abusoglu, S. / Yilmaz, H. / Tutkun, E. et al. | 2014
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Exposure to crack cocaine smoke, a new animal modelHueza, I. / Ponce, F. / Garcia, R. / Mantovani, C. / Marcourakis, T. et al. | 2014
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Ten-year trends of hospital admissions due to acute poisoning in SloveniaPerharic, L. / Simon, M. R. / Zgaga, A. / Soemen, A. et al. | 2014
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An MI prescribedAbraham, S. V. / Vimal Krishnan, S. / Kassyap, C. K. et al. | 2014
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Atomic absorption spectrometry and ICP-MS methods used to evaluate the arsenic intake in a toxicity assay on Daphnia magnaGutu, C. M. / Preoteasa, V. / Olaru, O. T. / Purdel, C. N. / Ilie, M. / Manda, G. / Balalau, D. et al. | 2014
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Human exposure to formaldehyde, a risk evaluation of occupational health effectsCosta, S. / Costa, C. / Garcia-Leston, J. / Coelho, P. / Silva, S. / Carvalho, S. / Laffon, B. / Porto, B. / Teixeira, J. P. et al. | 2014
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A case study of in vitro phototoxicity testing under Regulation 1107/2009: Implications for agrochemical risk assessmentAggarwal, M. / Corvaro, M. / Mehta, J. et al. | 2014
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Research of fungicides, acaricides and herbicides in fish Prochilodus costatus in Sao Francisco River BrazilOliveira, F. A. / Reis, L. d. / Soto-Blanco, B. / Melo, M. et al. | 2014
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Highly selective MRM3 identification and quantitation of cortisol and cortisone in human hair using an online SPE LC-ESI/MS^3 method in negative modeQuinete, N. S. / Bertram, J. / Lang, J. / Kraus, T. et al. | 2014
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Optimized ultrasound-assisted dispersive liquid-liquid microextraction for simultaneous trace multielement determination of heavy metals in environmental water samples by ICP-MSWang, X. / Chen, J. / Zhou, Y. / Wang, L. et al. | 2014
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Establishment of rodent and human in vitro systems for the investigation of testicular toxicityGastaldello, A. / Escoffier, J. / Kustermann, S. / Clemann, N. / Nef, S. / Stoppini, L. et al. | 2014
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Embryonic stem cells carrying a transgenic BMP-reporter construct: A useful tool for the identification and analysis of teratogenic compounds in vitroKugler, J. / Tharmann, J. / Lopez, S. M. / Christine, M. / Rolf, K. / Luch, A. / Oelgeschlager, M. / Hasse, A. et al. | 2014
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Co-culture of B-13 hepatocyte progenitors with liver myofibroblasts promotes progenitor WNT signalling repression in response to glucocorticoids and enhances their transdifferentiation towards hepatocyte-like cellsFairhall, E. / Wallace, K. / Wright, M. et al. | 2014
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A primary fish gill cell model to assess xenobiotic transport and bioconcentration in fishStott, L. / Schnell, S. / Hogstrand, C. / Owen, S. / Bury, N. et al. | 2014
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Including metabolic activation into an in vitro nuclear receptor transactivation assayBellion, P. / Bendik, I. / Duesterloh, A. / Thiel, A. / Beilstein, P. et al. | 2014
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Effects of biologically active tributyl-/triphenyl-organometal ligands of retinoid X receptors in human breast cancer cell lineMacejova, D. / Bialesova, L. / Toporova, L. / Brtko, J. et al. | 2014
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Hexachlorobenzene promotes angiogenesis in vivo, in a breast cancer model and neovasculogenesis in vitro, in the human endothelial cell line HMEC-1Pontillo, C. / Espanol, A. / Chiappini, F. / Miret, N. / Cocca, C. / Alvarez, L. / de Pisarev, D. K. / Sales, M. E. / Randi, A. et al. | 2014
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Evaluation of photodegradation and photogenotoxicity of ofloxacin in ointments with sunscreensZgadzaj, A. / Skrzypczak, A. / Welenc, I. / Lugowska, A. / Siedlecka, E. / Nalecz-Jawecki, G. et al. | 2014
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Chemopreventive effects of methionine on benzo[a]pyrene (B[a]P)-DNA adducts formation in human hepatocellular carcinoma cellsPark, H. J. / Shin, M. k. / Lee, J. D. / Kim, J. Y. / Gwak, H. M. / Hyeon, J. H. / Um, Y. M. / Son, J. Y. / Kim, K. s. / Sachan, R. et al. | 2014
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Utilising knowledge relating to 5a-reductase inhibition in the prediction of teratogenicityCayley, A. / Drewe, W. / Kruhlak, N. / Surfraz, M. B. et al. | 2014
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Harnessing mathematical models and uncertainty in toxicological risk assessmentsGosling, J. P. et al. | 2014
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The simultaneous use of multiple imaging techniques to investigate the nature and localisation of radioactivity within micro-structures surrounding the rat brainStevenson, K. / Mackay, C. / Brogan, L. / Molander-Melin, M. / Gardiner, P. / Aberg, P. / Larsson, B. et al. | 2014
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Evaluation of the mutagenic potential of the three asarone isomersBerg, K. / Esselen, M. / Schrenk, D. et al. | 2014
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ROS production and GSH content of Caco-2 cells exposed to silane-modified claysMaisanaba, S. / Pichardo, S. / Jorda-Beneyto, M. / Camean, A. M. / Aucejo, S. / Jos, A. et al. | 2014
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Steroid-like activity of migration products from non polycarbonate plastic baby bottlesSimon, C. / Onghena, M. / Covaci, A. / Van Hoeck, E. / Van Loco, J. / Vandermarken, T. / Demaegdt, H. / Mertens, B. / Vandermeiren, K. / Elskens, M. et al. | 2014
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In vivo micronucleus/OECD 474 studies with 6 titanium dioxide materials (3 pigment-grade and 3 nanostructured) demonstrate negative in vivo genotoxicity effects in orally exposed ratsMyhre, A. / Boatman, R. / Warheit, D. et al. | 2014
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A proteomics approach to elucidate the role of Nrf2 in primary bone-marrow-derived dendritic cells of mice upon activation by contact allergensMussotter, F. / Haase, A. / Tomm, J. M. / Ali, Z. E. / Kerdine-Romer, S. / Pallardy, M. / von Bergen, M. / Luch, A. et al. | 2014
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Retrospective analysis of guinea pig systemic anaphylaxis resultsDescotes, J. / Duclos, M. E. / Haag, V. / Forster, R. et al. | 2014
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Analysis of in chemico and in silico methods to predict skin sensitization potentialsUrbisch, D. / Honarvar, N. / Mehling, A. / Kolle, S. / Teubner, W. / Landsiedel, R. et al. | 2014
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A survey data on ecotoxicological synergistic effects from binary pesticide mixturesKim, J. / Pasupuleti, R. / Kim, S. et al. | 2014
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Effects of platycodin D on reflux esophagitis due to modulation of antioxidant defense systemsCho, S. Y. / Song, C. H. / Lee, J. E. / Choi, S. H. / Park, S. J. / Ku, S. K. et al. | 2014
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First biomonitoring data for the nephrotoxic mycotoxins citrinin and ochratoxin A in BangladeshDegen, G. / Ali, N. / Blaszkewicz, M. / Hossain, K. et al. | 2014
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Market survey of aromatic amines in textiles and leathers to support health Canada's Chemicals Management PlanField, J. / Ritchot, N. / Chantal, P. / Aikawa, B. / Barrett, G. / Pelletier, P. / Ryan, H. / Sutton, C. et al. | 2014
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Increased sensitivity in clinical signs and electrocardiography monitoring linked to improvements in cage design and animal husbandry for macaquesPalmer, H. / Meecham, K. / Crome, S. et al. | 2014
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Acute administration of vinpocetine, a phosphodiesterase type 1 inhibitor, mitigates locomotor hyperactivity in female mice exposed to lead during developmentFilgueiras, C. / Araujo, U. / Nunes, F. / Goncalves, B. / Gomes, R. / Moreira, M. / Manhaes, A. / Abreu-Villaca, Y. et al. | 2014
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Localisation of novel miRNA biomarkers of doxorubicin-induced cardiotoxicity in ratsBarnes, C. / Kelsall, J. / Smith, S. / Cove-Smith, L. / Mellor, H. / Hargreaves, A. / Price, S. et al. | 2014
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Electrochemical generation of reactive drug metabolites - Applications in drug discovery and developmentJurva, U. et al. | 2014
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Seasonal changes in airborne concentrations of organic solvents and genetic variability of selected genes affect the levels of selected markers of oxidative stress and DNA damage among nail techniciansGresner, P. / Swiercz, R. / Stepnik, M. / Gromadzinska, J. / Twardowska, E. / Wasowicz, W. et al. | 2014
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An evaluation of the mode of action (MoA) and human relevance of rat liver tumours observed in a chronic rat feeding study with silthiofamKronenberg, J. M. / Haines, C. / Elcombe, B. M. / Elcombe, C. R. et al. | 2014
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Organotin compounds cause structure-dependent induction of progesterone in human choriocarcinoma jar cellsNakanishi, T. / Hiromori, Y. / Nagase, H. et al. | 2014
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Estimation of toxic effect of acetaminophen metabolite in isolated mitochondriaNydlova, E. / Vrbova, M. / Kucera, O. / Cesla, P. / Cervinkova, Z. / Rousar, T. et al. | 2014
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BaltMPI: A new metalloprotease inhibitor from Bothrops alternatus snake serumPalacio, T. Z. / Santos-Filho, N. A. / Barraviera, B. / Ferreira Junior, R. S. / Rosa, J. C. / Sampaio, S. V. et al. | 2014
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Bile acids profiling of rat plasma after treatment with Cyclosporin ASchadt, H. / Stiehl, D. / Schwald, M. / Vieira, C. V. / Dietz, A. / Penno, C. / Chibout, S. D. / Moulin, P. / Pognan, F. / Wolf, A. et al. | 2014
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Does divalent metal transporter 1 mediate the intestinal absorption of arsenic?Kayaalti, Z. / Akyuzlu, D. K. / Turksoy, V. A. / Soylemez, E. / Soylemezoglu, T. et al. | 2014
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Dermal dosing studies in juvenile minipigsMakin, A. / Lykke, M. / Logsted, J. et al. | 2014
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l-amino acid oxidase from Calloselasma rhodostoma potentiates tyrosine kinase inhibitors effect in Bcr-Abl positive cellsBurin, S. / Costa, T. / Ghisla, S. / Ambrosio, L. / Tavares, C. / Bianchini, F. / Torqueti, M. R. / Sampaio, S. / Castro, F. et al. | 2014
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Bacterial transformation of mercury in a polluted environment: Impact on human healthFigueiredo, N. / Canario, J. / Duarte, A. / Carvalho, C. et al. | 2014
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Toxicity of ethanol industry waste in the test organism Oreochromis niloticus (pisces)Fontanetti, C. / Correia, J. / Marinho, J. / Christofoletti, C. / Souza, R. et al. | 2014
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Kinetic studies of hydroxamate and functionalized oximate ions for hydrolysis of organophosphorus compoundsDewangan, H. / Satnami, M. et al. | 2014
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Spatial and seasonal variation in chemical composition and toxicological response of ambient particulate matterMichael, S. / Dott, W. et al. | 2014
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Arithmetic method of rough estimation of median lethal dose (LD50) using up-and-down procedureSaganuwan, S. A. et al. | 2014
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Application of ICP OES to determination of cadmium, selenium and chromium in tissues in postmortem materialLech, T. / Mondrag@?n, V. et al. | 2014
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An integrated SAR- and analogue-based approach to chemical safety assessmentPetry, T. / Autiero, M. / Jeronimo-Roque, D. / Tencalla, F. et al. | 2014
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Risk ranking priority of carcinogenic and/or genotoxic environmental contaminants in food in BelgiumVromman, V. / Maghuin-Rogister, G. / Vleminckx, C. / Saegerman, C. / Pussemier, L. / Huyghebaert, A. et al. | 2014
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In vitro study on inhibitory effects of infusions made from two kinds of tea on lipid peroxidation induced by malondialdehydeEbadollahinatanzi, A. / Shooli, A. et al. | 2014
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A zebrafish embryotoxicity test detects the developmental toxicity of thyroid-active compoundsJomaa, B. / Hermsen, S. / Kessels, M. / Van den Berg, J. / Peijnenburg, A. / Aarts, J. / Piersma, A. / Rietjens, I. et al. | 2014
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Hepatotoxicity of drug compounds in four species (human, dog, cynomulgus primate, and rat) in long-enduring, stable HmREL hepatocyte co-culture modelsNovik, E. / Parekh, A. / Cho, C. / Pludwinski, E. / Freedman, R. et al. | 2014
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UCX cells: A primordial stem cell source for in vitro differentiation into hepatocyte-like cells (HLCs)Cipriano, M. / Medeiros, A. / Filipe, E. / Santos, J. M. / Barcia, R. / Cruz, H. / Cruz, P. / Oliveira, N. G. / Miranda, J. P. et al. | 2014
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Airborne exposure of A549 air-liquid-interphase cultures to formaldehyde at low ppm by using a novel exposure incubator systemGostner, J. / Zeisler, J. / Uberall, S. / Becker, K. / Gruber, P. / Naschberger, M. / Martini, S. / Kleinhappl, M. / Uberall, F. et al. | 2014
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The highly differentiated 3D epidermal skin model (epiCS) to characterize skin sensitizers in mixturesPratt, L. F. / Troese, M. J. / Fuchs, H. W. / Engelking, O. / DeGeorge, G. L. et al. | 2014
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Fumonisin B1 induces global DNA hypomethylation and modulates cytochrome P450 1B1 (CYP1B1) by repressing miR-27b in HepG2 cellsChuturgoon, A. / Phulukdaree, A. / Moodley, D. et al. | 2014
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Effect of Cu[15]pyN5 on MDA-MB-231 cell migration and invasionFernandes, A. S. / Florido, A. / Saraiva, N. / Cerqueira, S. / Cipriano, M. / Fatima Cabral, M. / Miranda, J. P. / Castro, M. / Costa, J. / Oliveira, N. G. et al. | 2014
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Cytotoxic and genotoxic activity of hesperetin in an osteosarcoma in vitro modelCoutinho, L. / Ferreira de Oliveira, J. M. / Oliveira, H. / Santos, C. et al. | 2014
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Assessment of cadmium as a tobacco smoke toxicant using in vitro genotoxicity and physiologically-based pharmacokinetic (PBPK) ModellingCunningham, F. / Fiebelkorn, S. / Dillon, D. / Meredith, C. et al. | 2014
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Basic approach to optimize the small drug seeds with minimized CV risks on the early stage of drug discovery by using small molecule-based in silico models for prediction of hERG/Nav1.5 inhibitionsDodo, T. / Ikemori Kawada, M. / Yu, M. / Yoshinaga, T. / Inoue, A. / Sawada, K. et al. | 2014
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Comparison of body weight and food consumption in young adult SD rats from three different vendorsMcPherson, S. et al. | 2014
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The food contaminants aflatoxin B1, fumonisin B1, ocratoxina, T-2 toxin and deoxynivalenol decrease intestinal barrier permeability in human Caco-2 cells. Protector role of clay additivesAnadon, A. / Martinez, M. A. / Ares, I. / Ramos, E. / Castellano, V. / Martinez, M. / Martinez-Larranaga, M. R. / Romero, A. et al. | 2014
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Monitoring of pesticides residues in Greek bottled wineTsakiris, I. / Tzatzarakis, M. / Alegakis, A. / Mitlianga, P. / Kavvalakis, M. / Vakonaki, E. / Goumenou, M. / Stivaktakis, P. / Tsatsakis, A. et al. | 2014
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Carcinogenic potential of Ag-NP using Balb/c 3T3 A31-1-1 cell transformation assayChoo, W. H. / Lee, J. E. / Cho, H. S. / Oh, S. M. et al. | 2014
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Analysis of the preventive effect of Ginkgo biloba on renal effects of titanium dioxide nanoparticles in adult male ratsEscarcega-Gonzalez, C. E. / Rodriguez-Vazquez, M. L. / Jaramillo-Juarez, F. / De La Cerda-Gonzalez, E. / Martinez-Ruvalcaba, H. / Rio, F. A. / Escalante-Acosta, B. A. et al. | 2014
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Toxic effects induced by poly(amidoamine) dendrimers in Allium cepaFreire, P. F. / Martin, J. M. / Peropadre, A. / Aquilino, M. / Rosal, R. / Hazen, M. J. et al. | 2014
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Toxicological evaluation of reference silver nanoparticles NM300K in mammalian cellsNguyen, K. / Richards, L. / Rippstein, P. / Tayabali, A. et al. | 2014
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The effects of Cd and BDE-209 co-exposure on hematological parameters in ratsCurcic, M. / Stankovic, S. / Vucinic, S. / Jacevic, V. / Brkic, D. / Djukic-Cosic, D. / Antonijevic, E. / Antonijevic, B. et al. | 2014
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Effects of pyriproxyfen and Bacillus thuringiensis in midgut antioxidant enzymes and lipid peroxidation levels of Galleria mellonella larvae exposed to these insecticides singly and mixtureSezer, B. / Ozalp, P. et al. | 2014
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Biochemical markers in long-term exposed rabbits to nandrolone decanoateVasilaki, F. / Tsitsimpikou, C. / Tsarouhas, K. / Ozcagli, E. / Fragkiadaki, P. / Heretis, I. / Kovatsi, L. / Kyriakakis, M. / Tsatsakis, A. et al. | 2014
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Aryl hydrocarbon receptor mode-of-action and human relevance framework for halauxifen-methyl induced rodent liver effectsMurphy, L. / LeBaron, M. / Marshall, V. / McCoy, A. / Kan, L. / Boverhof, D. / Bartels, M. / Terry, C. / Billington, R. / Rasoulpour, R. et al. | 2014
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UHPLC/DAD determination of formaldehyde released in the air from use at high temperatures of cosmetic products for hair straighteningDe Dominicis, E. / Bettin, F. / Commissati, I. / Metra, P. / Fidente, P. / Marinovich, M. / Galli, C. et al. | 2014
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Evaluation of methyl methanesulfonate induced lesions by laser scanning microscopyWeber, K. / Fendl, D. / Waletzky, A. / Hein, F. / Kunze, M. / Leoni, A. L. / Riedel, W. et al. | 2014
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Hepato-protective and anti-diabetic effects of Capsosiphon fulvescens and pheophorbide A in streptozotocin-induced diabetic ratsLee, K. W. / Kim, S. W. / Oh, J. S. / Nam, M. H. / Hong, C. o. et al. | 2014
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Does developmental exposure to bisphenol A induce bone and adipose tissue disturbances?Lejonklou, M. H. / Karimullina, E. / Larsson, S. / Lind, T. / Melhus, H. / Rasmusson, A. J. / Ronn, M. / Riserus, U. / Blumberg, B. / Lind, P. M. et al. | 2014
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Urinary protein-based biomarkers for evaluation of chemical-induced nephrotoxicitySon, J. Y. / Kim, K. S. / Kang, Y. J. / Sik, H. et al. | 2014
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AOP strategy: shaping the future for human health and environmental risk assessmentWhelan, M. et al. | 2014
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Global miRNA profiling for biomarker discovery - What is normal?Tonge, D. / Gant, T. et al. | 2014
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The genetic toxicity of complex mixtures of polycyclic aromatic hydrocarbonsLong, A. S. / Lemieux, C. L. / Arlt, V. M. / White, P. A. et al. | 2014
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Safety assessment of proteins utilized in agricultural biotechnologyLadics, G. et al. | 2014
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Allergic potential of proteins, from vivo to vitroSmit, J. et al. | 2014
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Carcinogenicity and genotoxicity of furan in rats in vivoMally, A. et al. | 2014
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Epidemiological findings on health risks associated with dietary acrylamideHogervorst, J. et al. | 2014
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Mechanistic steps in the immune response to skin sensitising chemicalsKimber, I. et al. | 2014
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Non-intentionally added substances in food contact materials: EU regulatory requirements and safety assessmentKetelslegers, H. et al. | 2014
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Enough precision to make a decision: The HESI RISK21 perspectivePastoor, T. et al. | 2014
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Assessing safety of non-intentionally added substances in polymers used for food contact applicationsHollnagel, H. M. / van Herwijnen, P. / Sura, P. et al. | 2014
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EFSA's draft risk assessments of bisphenol A (BPA), the increasing role of uncertaintyHusoy, T. / Hart, A. D. / Pirow, R. / Pocas, M. d. / Mennes, W. C. / Wolfle, D. / Arcella, D. / Theobald, A. / Croera, C. / Castoldi, A. F. et al. | 2014
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Analysis of the influence of vehicles on the sensitizing potential of 3 allergenic compoundsBerrada-Gomez, M. P. / Dalhuchyts, H. / Rattier, S. / Bidan, C. / Groux, H. / Ferret, P. J. et al. | 2014
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Development and optimization of the epiocular eye irritation test (EpiOcular EIT) for solid materials addressing the EU cosmetic legislation and reachKaluzhny, Y. / Kandarova, H. / d'Argembeau-Thornton, L. / De Luca, J. / Hayden, P. / Hunter, A. / Truong, T. / Klausner, M. et al. | 2014
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Implication of DEB theory in assessment of mixture toxicity of chemicals with dissimilar mode of action to Daphnia magnaMatyja, K. / Grabas, K. et al. | 2014
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Developmental toxicity of phthalates - Read across approachSaillenfait, A. M. / Sabate, J. P. et al. | 2014
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Towards an MIE atlas - Definition and roleAllen, T. / Goodman, J. / Gutsell, S. / Russell, P. et al. | 2014
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Validation of the minimally invasive blood pressure telemetry technique for use in repeat-dose toxicology studiesGrant, C. / Stanton, A. / Sutherland, J. / Billings, R. / Moors, J. / Milne, A. / Finch, J. et al. | 2014
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'Smart' but not safe: The potential hepatotoxicity of synthetic cathinonesAraujo, A. M. / Valente, M. J. / da Silva, D. D. / Carvalho, M. / Carvalho, F. / Bastos, M. d. / de Pinho, P. G. et al. | 2014
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Mechanism underlying the dioxin-produced retardation of offspring growth: The role of a reduction in the fetal expression of growth hormoneHattori, Y. / Takeda, T. / Fujii, M. / Ishii, Y. / Yamada, H. et al. | 2014
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Activation of caspase-4 is a critical step in saikosaponin-induced apoptosisKang, S. J. / Lee, E. K. / Ku, S. K. / Lee, Y. J. et al. | 2014
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Blood endocrine disruptor levels in cryptorchidic newbornsUlutas, O. K. / Cok, I. / Darendeliler, F. / Aydin, B. / Coban, A. / Henkelmann, B. / Schramm, K. W. et al. | 2014
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Heart ultrasound measurements in long-term exposed rabbits to nandrolone decanoateGermanakis, I. / Tsarouhas, K. / Vasilaki, F. / Tsitsimpikou, C. / Vardavas, A. / Fragkiadaki, P. / Liesivuori, J. / Datseri, G. / Tsatsakis, A. et al. | 2014
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Human risk assessment and GC/MS analysis of phthalates in excipients for pharmaceuticalsKim, H. S. / Hyeon, J. H. / Shin, M. K. / Park, H. J. / Lee, J. D. / Kim, J. Y. / Gwak, H. M. / Um, Y. M. / Son, J. Y. / Kim, K. S. et al. | 2014
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Assessment of irritant contact dermatitis risk for healthcare workers using medical glovesEskov, A. / Sokolov, A. / Zaitsev, O. / Robin, R. et al. | 2014
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Urinary selenium excretion in children and adults from Northern PolandDziadziuszko, M. / Wielgomas, B. et al. | 2014
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Risk assessment of indoor exposure to formaldehyde: A potential threatDomingo, J. L. / Rovira, J. / Roig, N. / Schuhmacher, M. / Nadal, M. et al. | 2014
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Text mining for improved human exposure assessmentLarsson, K. / Silins, I. / Guo, Y. / Korhonen, A. / Stenius, U. / Berglund, M. et al. | 2014
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Significance of nail mercury concentrations as a biomarker of prenatal methylmercury exposure in relation to segmental hair mercury concentrations at parturitionSakamoto, M. / Chan, H. M. / Domingo, J. L. / Oliveira, R. / Murata, K. et al. | 2014
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Cyto and genotoxic effects of silver nanoparticles on A549 cell lineRosario, F. / Reis, C. / Santos, C. / Oliveira, H. / Ferreira de Oliveira, J. M. et al. | 2014
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The mammalian cell in-vitro Pig-A gene mutation assay: Investigating the genotype to phenotype relationshipRees, B. / Thornton, C. / Jenkins, G. / Dow, D. / Mehta, N. / Field, L. / Johnson, G. et al. | 2014
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Validation study on the ocular Irritection assay for eye irritation testingEskes, C. / Hoffmann, S. / Facchini, D. / Ulmer, R. / Wang, A. / Vassallo, M. / Flego, M. / Bufo, M. / van Vliet, E. / d'Abrosca, F. et al. | 2014
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Characterization of uptake and efflux transporters in fresh isolated and cryopreserved primary hepatocytes of different species by using radiolabeled substratesKeiser, M. / Ullrich, A. / Jia, J. / Patrzyk, M. / Busemann, A. / Heidecke, C. D. / Siegmund, W. / Runge, D. et al. | 2014
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Characterization of heterotypic 3D human liver microtissues for drug-induced hepatotoxicity testingGunness, P. / Messner, S. / Fredriksson, L. / Kelm, J. / Moritz, W. / Ingelman-Sundberg, M. et al. | 2014
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Novel 3-D human small intestinal tissue model to assess drug permeation, inflammation, and wound healingAyehunie, S. / Stevens, Z. / Landry, T. / Klausner, M. / Hayden, P. / Letasiova, S. et al. | 2014
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Activity of b-glucosidase in plants with high content of cyanogenic glycosides as important factor determining their toxicitySchneider, L. / Buhrke, T. / Lampen, A. / Abraham, K. et al. | 2014
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Neurotoxic effects induced subchronically by CYN in tilapias and their reversion after two different depuration periodsLomares, I. / Rios, V. / Guzman-Guillen, R. / Prieto, A. I. / Moreno, I. M. / Blanco, A. / Moyano, R. / Camean, A. M. et al. | 2014
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In vitro pro-oxidant/antioxidant role of an extract from Allium essential oil in the intestinal Caco-2 cell lineLlana-Ruiz-Cabello, M. / Gutierrez-Praena, D. / Pichardo, S. / Abad, P. / Lopez, J. D. / Guillamon, E. / Camean, A. M. et al. | 2014
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Flow cytometry study of the Caco-2 cell line exposed to a silane-modified clayMaisanaba, S. / Cabral-Monge, M. C. / Gutierrez-Praena, D. / Jorda-Beneyto, M. / Aucejo, S. / Jos, A. et al. | 2014
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Determination of Alternaria mycotoxins in strawberries and storage conditionsJuan, C. / Chamari, K. / Juan-Garcia, A. / Manes, J. et al. | 2014
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Formation of DNA adducts in wt and transgenic mice expressing human sulfotransferases after treatment with heterocyclic amines and furansSaether, A. H. / Monien, B. / Glatt, H. R. / Hjertholm, H. / Svendsen, C. / Alexander, J. / Husoy, T. et al. | 2014
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The contribution of silica nanoparticles-induced neutrophilia to pregnancy complications in miceHigashisaka, K. / Kunieda, A. / Iwahara, Y. / Tanaka, K. / Tsunoda, S. i. / Yoshioka, Y. / Tsutsumi, Y. et al. | 2014
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Comparison of two different application routes of nanosilver in rats - A toxicokinetic studyHorzowski, S. / Lichtenstein, D. / Potkura, J. / Oberemm, A. / Creutzenberg, O. / Lampen, A. et al. | 2014
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How nanomaterials will interfere with the toxicity of copper?Bouguerra, S. / Gavina, A. / Ksibi, M. / Rasteiro, M. d. / Rocha-Santos, T. / Pereira, R. et al. | 2014
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Effect of different doses of cadmium chloride on interleukin-2, lymphocyte transformation and DNA fragmentation in adult male albino ratsElhady, K. / Kamal, A. / Gawish, R. et al. | 2014
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A comparative validation of simple additive models and integrated addition models for predicting mixture toxicityKim, J. / Pasupuleti, R. / Kim, S. et al. | 2014
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Effects of herbal extracts on the human granulocyte colony stimulating factor treated micePark, S. J. / Kim, S. M. / Lee, C. H. / Kim, S. G. / Kang, S. J. / Lee, E. K. / Lee, J. E. / Song, C. H. / Lee, Y. J. / Ku, S. K. et al. | 2014
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Peptidomics based serum biomarkers for mice exposed to benzeneZhang, J. / Tan, K. / Wei, H. / Sun, R. / Yin, L. / Pu, Y. et al. | 2014
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Applying the 3Rs principle in research studies relevant to the European Welfare Regulation on the protection of animals at the time of killingLeuschner, R. G. / Browman, H. I. / Raj, M. / Velarde, A. et al. | 2014
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''Mother-placenta-fetus'' system at environmental troubleZhumabayeva, A. / Jumanazarov, N. / Gumarova, Z. / Natalya, Z. et al. | 2014
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Effects of monocarboxylate transporter 1 (MCT1) inhibition on cardiac function under ischaemic conditions: A comparison between rat and guinea-pig Langendorff heartsMartin, E. / Lainee, P. / Prior, H. / Reens, J. / Smith, S. / Stucker, O. / Redfern, W. et al. | 2014
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The role of Pin1 in liver fibrosis: Regulation of Tgf-b1 expression and Smad2/3 phosphorylationYang, J. W. / Wook, K. et al. | 2014
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Target organ profiles in toxicity studies supporting human dosing: An assessment of recovery and chronic dosingHorner, S. / Lees, D. / Robinson, S. / Callander, R. / Roberts, R. et al. | 2014
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Quantitative inter-species comparison approach of 1,3-butadiene metabolism based on in vitro enzyme kinetics using cob(I)alamin and in vivo AUC from haemoglobin adductsMotwani, H. / Tornqvist, M. et al. | 2014
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Covalent interactions of reactive rimonabant metabolites with biological targetsThorsell, A. / Breitholtz, K. / Jurva, U. / Isin, E. et al. | 2014
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Advancing scientific innovation towards improved public healthGant, T. W. et al. | 2014
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The contribution of toxicology to basic biology and molecular and cell biology to the development of in vitro toxicology testingVilanova, E. et al. | 2014
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Early microRNA and other non-coding RNA biomarkers for rodent non-genotoxic carcinogensEllinger-Ziegelbauer, H. / Toft, D. B. / Braeuning, A. / Couttet, P. / DaCosta, A. / Dhalluin, S. / Eichner, J. / Elcombe, C. R. / Grenet, O. / Henderson, C. et al. | 2014
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London air quality: A real world experiment in progressKelly, F. et al. | 2014
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Neurodevelopmental effects of bisphenol A and phthalates studied in in ovo exposed chicken to model prenatal exposureRakkestad, K. E. / Mathisen, G. / Austdal, L. P. / Paulsen, R. E. et al. | 2014
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DNA damage and antioxidant capacity produced by beauvericin, zearalenone and its metabolites in CHO-K1 cellsMallebrera, B. / Tatay, E. / Font, G. / Ruiz, M. J. et al. | 2014
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DNA damage and perturbation on cell cycle and mitochondrial membrane potential by alternariol mycotoxin in Caco-2 cellsFernandez-Blanco, C. / Juan-Garcia, A. / Font, G. / Ruiz, M. J. et al. | 2014
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EUROTOX 2014 Sponsor Logos| 2014
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Are non-monotonic dose-responses at low dose levels toxicologically relevant?| 2014
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MicroRNA modulation of organismal response to environmental exposuresKoufaris, C. et al. | 2014
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Harmonisation of ecological and human risk assessment of chemical mixturesRagas, A. et al. | 2014
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New tools for evidence-based risk assessment of chemical mixturesAmzal, B. / Quignot, N. / Dorne, J. L. / Bois, F. / Bechaux, C. et al. | 2014
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Cardiotoxicity of anabolic steroids; animal case study of oral turinabol and methanabolTsitsimpikou, C. et al. | 2014
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Evaluating MoE and its uncertainty and variability for food contaminantsSetzer, R. W. et al. | 2014
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Current understanding and new paradigms to tackle DILI predictionPark, K. et al. | 2014
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Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1' hydroxyestragole to a genotoxic species - An animal donor-free in vitro screen for phase II activated genotoxinsProbert, P. / Alhusainy, W. / Rietjens, I. / Wright, M. et al. | 2014
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Toxicity of selected bioactivated compounds in primary rat hepatocytes cultured in micropatterned co-culturesUkairo, O. / Shi, J. / Jackson, J. / Rose, K. / Andersen, M. / LeCluyse, E. et al. | 2014
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Time course of arsenic-induced alterations in paraoxonase activity in male albino rats: Comparison between pentavalent inorganic and organic arsenic through drinking waterAdemuyiwa, O. / Fatoki, J. / Ugbaja, R. / Afolabi, O. / Ogunrinola, O. / Wusu, A. / Abam, E. / Dosumu, O. / Babayemi, D. / Onunkwor, O. et al. | 2014
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The effect of dioxin on hepatic metabolome and leukotriene B4 synthetic pathwayKomiya, Y. / Takeda, T. / Koba, A. / Ishii, Y. / Kikuta, Y. / Uchi, H. / Furue, M. / Yamada, H. et al. | 2014
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Gene expression profiling of human bronchial epithelial cells exposed to seasonal Milan particulate matterLonghin, E. / Capasso, L. / Battaglia, C. / Cosentino, C. / Proverbio, M. C. / Cifola, I. / Mangano, E. / Camatini, M. / Gualtieri, M. et al. | 2014
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'Aerobically poised' leukaemia cells are resistant to the mitochondrial toxin and BCL-2/BCL-XL inhibitor, ABT-737Miles, G. / Langlais, C. / MacFarlane, M. / Cain, K. et al. | 2014
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Cell specific targeting for mechanistic studies of testicular toxicity using LCM and RT-PCRRiggall, L. / Gresham, S. / Vidgeon-Hart, M. / Lowe, R. / Kenny, S. / Baker, D. / Nicholls, A. et al. | 2014
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Polyhexamethylene guanidine-phosphate induces inflammatory and fibrotic responses in air-liquid interface co-culture modelKim, H. R. / Shin, D. Y. / Chung, K. H. et al. | 2014
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The role of NF-kB signaling in polyhexamethylene guanidine-phosphate induced inflammatory response in mouse macrophage raw 264.7 cellsShin, D. Y. / Park, C. W. / Choo, W. H. / Cho, H. S. / Chung, K. H. et al. | 2014
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Isolation of a novel serine proteinase from Lachesis muta rhombeata venom with kallikrein-like activityWiezel, G. / Bordon, K. / Gomes, M. / Rodrigues, V. / Arantes, E. et al. | 2014
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Effect of HFE H63D polymorphism on blood lead levels of mothers and their newbornsKayaalti, Z. / Akyuzlu, D. K. / Soylemez, E. / Soylemezoglu, T. et al. | 2014
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Toxicokinetic analysis in single dose study in juvenile rats treated orally with quinidineTanaka, Y. / Miida, H. / Fujita, K. / Kato, Y. / Ozawa, M. / Niino, N. / Yamoto, T. / Takasaki, W. et al. | 2014
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Genotoxic effects of diamine putrescine assessed by comet assay in Wistar ratsPereira, F. / Hara, R. / Goncalves, L. / Franco, L. / Curtolo, R. / Alves, G. / Severi-Aguiar, G. / Marin-Morales, M. et al. | 2014
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Effect of tonalide on early life stages of common carpTumova, J. / Steinbach, C. / Kumar, V. / Fedorova, G. / Machova, J. / Grabic, R. / Vanecek, M. / Piackova, V. / Kroupova, H. K. et al. | 2014
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The effect of saxitoxin on the differentiation of D3 embryonic stem cells into a neural lineageO'Neill, K. / Musgrave, I. et al. | 2014
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Speciation of manganese in drinking waterRumsby, P. / Rockett, L. / Clegg, H. / Jonsson, J. / Benson, V. / Harman, M. / Doyle, T. / Rushton, L. / Wilkinson, D. / Warwick, P. et al. | 2014
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Environmental contamination of lead: challenges for protecting future generationsPena-Fernandez, A. / Gonzalez-Munoz, M. J. / Lobo-Bedmar, M. d. et al. | 2014
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Evaluation of relative telomere length in agricultural workers exposed to multiple pesticidesMladinic, M. / Bjelis, M. / Zeljezic, D. et al. | 2014
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Tetrahydroxylated-benzo[a]pyrene isomer analysis after hydrolysis of DNA-adducts isolated from white blood cellsGrova, N. / Hardy, E. M. / Salquebre, G. / Schroeder, H. / Appenzeller, B. M. et al. | 2014
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In vitro screening of thyroid function disruption: PC-Cl3 cell line, a promising toolDallot, C. / Blanck, O. / Hilmi, C. / Bars, R. / Risso-de Favernay, C. et al. | 2014
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THE glucocorticoid-dependent conversion of the B-13 progenitor cell into hepatocyte-like (B-13/H) cells is dependent on a short exposure to glucocorticoid and epigenetic alterationsCharles, M. / Wallace, K. / Probert, P. / Oakley, F. / Wright, M. et al. | 2014
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Environmental polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53 dependent mechanismWohak, L. U. / Krais, A. M. / Kucab, J. E. / Ovrebo, S. / Seidel, A. / Phillips, D. H. / Arlt, V. M. et al. | 2014
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Identification of structural alerts for mitochondrial toxicity using chemotyperMadden, J. / Nelms, M. / Cronin, M. / Enoch, S. et al. | 2014
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Pharmacokinetic profile of RPH-203, a RANKL blocker, following subcutaneous and intravenous administration in the Cynomolgus monkeyLavrovsky, Y. / Archuadze, S. / Oshodi, T. / Dwivedi, P. et al. | 2014
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Use of mulitple in silico genetic toxicity alerting tools for the prioritisation of compounds in the tres cantos antimalarial set (TCAMS)Gresham, S. / Castaneda-Casado, P. / Jimenez-Navarro, E. / Giddings, A. / Hattotuwagama, C. / Robinson, S. / Harvey, J. et al. | 2014
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Development of a liquid chromatography-tandem mass spectrometry for the determination of enniatins in biological samples from Wistar ratsEscriva, L. / Font, G. / Manyes, L. et al. | 2014
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Impact of an acrylamide-niacin adduct on the cellular redox status of human colon carcinoma cellsHaben, M. / Reiner, T. / Eisenbrand, G. / Esselen, M. et al. | 2014
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Cytotoxicity evaluation of two novel silane-modified clays for their use in nanocomposite packagingMaisanaba, S. / Pichardo, S. / Jorda-Beneyto, M. / Aucejo, S. / Jos, A. et al. | 2014
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Binary mixtures effects of food additives and cosmetic preservatives on an estrogen responsive cell linePop, A. / Drugan, T. / Loghin, F. / Gutleb, A. / Cherfan, J. / Kiss, B. et al. | 2014
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Al, Pb, Cd in red and brown edible seaweedsArmendariz, M. d. / Napoleone, G. / Abellan, T. R. / Weller, D. G. / Gonzalez, G. L. / Fernandez, A. J. / de la Torre, A. H. et al. | 2014
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Mechanisms behind toxicity of 11 metal oxide nanoparticles to alga Pseudokirchneriella subcapitataAruoja, V. / Pokhrel, S. / Sihtmae, M. / Vija, H. / Kahru, A. et al. | 2014
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Effects of titanium dioxide nanoparticles on the pneumonia in respiratory syncytial virus-infected miceHashiguchi, S. / Yoshida, H. / Akashi, T. / Hirose, A. / Kurokawa, M. / Watanabe, W. et al. | 2014
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Endocrine-modulating effects of polymeric nanoparticle poly (ethylene glycol)-block-poly (lactic acid) (PEG-b-PLA) on ovarian steroidogenesisScsukova, S. / Mlynarcikova, A. / Smolikova, K. / Kiss, A. / Rollerova, E. et al. | 2014
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ROS generation, apoptosis and autophagy play important roles in silver nanoparticles triggered cytotoxicity in Beas2B cellsWang, Y. J. / Lee, Y. H. / Mau, B. H. et al. | 2014
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Cytotoxic and genotoxic effects of perfluorododecanoic acid in Japanese medakaAyanda, I. / Min, Y. / Yu, Z. / Zha, J. / Obembe, O. et al. | 2014
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Allergen-induced langerhans' cell migration: Requirement for tumour necrosis factor alphaDearman, R. / Eaton, L. / Metryka, A. / Roberts, R. / Kimber, I. et al. | 2014
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ToxBox: Securing the drops of life-Risk assessment and regulation of anthropogenic pollutants in drinking water in the 21st centuryEckhardt, A. / Heinze, R. / Junek, R. / Grummt, T. et al. | 2014
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Strategy for nonclinical safety assessment to support GSK's malaria candidate vaccineDamsten, M. / Uwamwezi, M. C. / Segal, L. et al. | 2014
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Integration of transcriptomic, epigenomic, proteomic and metabolomic data for the characterisation of the molecular response of renal epithelial cells to repeat-dose exposure to chemicals in vitroLimonciel, A. / van Breda, S. / Jiang, X. / Tredwelll, G. D. / Wilmes, A. / Aschauer, L. / Theunissen, D. / Sachinidis, A. / de Kok, T. / Keun, H. C. et al. | 2014
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Amphetamine and its metabolite 4-hydroxyamphetamine neurotoxicity in differentiated SH-SY5Y neuronsFeio-Azevedo, R. / Costa, V. M. / Ferreira, L. P. / Branco, P. S. / Pereira, F. C. / de Lourdes Bastos, M. / Carvalho, F. / Capela, J. P. et al. | 2014
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Disposition of benzo[c]fluorene in ratsChopard-Lallier, M. / Perdu, E. / Jamin, E. / Brochot, C. / Cravedi, J. P. et al. | 2014
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IFC continued (editorial board)| 2014