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Evidence is reviewed that reorganization of visual messages with respect to color occurs in the central nervous system. In man, cat-fish and cat blue and red stimuli of equal brightness appear to undergo temporal differentiation in that red stimuli are transmitted more rapidly than blue. This has not so far been confirmed for monkey. In monkey cortex (the eye light adapted) more than half the single units responding to light did so with narrow spectral responsiveness. Different units responded to flashes through only one of four broad pass filters peaked at 450, 515, 587 or > 600 millimicrons. All single units with narrow spectral responsiveness to 560 millimicrons responded as well to one or two adjacent filters. The response of the same cells to optic nerve stimulation suggested that they lay on a one to one pathway from optic nerve to cortex. The different experimental conditions from those used in studies of monkey geniculate do not appear sufficient to explain the difference in results. It seems likely that the information available to single cortical cells is different from that at geniculate and that it is simpler. (Author)