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The maximum voluntary endurance of an isometric muscle contraction was examined in three groups of subjects: chronic hyperventilators, a control group with voluntary hyperventilation, and a second control group. During each endurance session subjects were requested to estimate task related levels of pain on a five-point scale. Continuous surface electromyographic monitoring was made of the dominant muscle. The results indicated that individuals with a chronic hyperventilation syndrome were more efficient in the utilization of muscles during a strenuous physical task when measured by mean amplitudes of the electromyographic representation of neuromuscular activity. It was proposed that a therapeutic approach to the syndrome might incorporate strenuous exercise to the symptomatology of excessive breathing. (Author)