Observations of Motor Reactions to Ions, Hormones, Pharmaceuticals, Electrical Stimulation and X Irradiation in Intraoperatively Removed Human Genital Preparations (Myometrium, Tuba Uterina and Genital Vessels)
(Englisch)
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Elementary physiological, pharmacological and radiological characteristics of isolated genital preparations - myometrium, tuba uterina and genital vessels - from human op material were compared and analysed. The basal tone and the spontaneous contractile activity were dependent on the sodium, potassium and calcium chloride concentration in the nutritive solution. Observations of the motor reactions of the preparations of myometrium and tuba uterina to hormones and their antagonists confirm or indicate the presence of specific hormone receptors. X-radiation caused a tonic contraction and changes in the spontaneous contractile activity in myometrium preparations. Uterine and ovarian vessels reacted to irradiation with definite and often enduring tonic contractions. Theophylline, a substance with an inhibiting affect on phosphodiesterase, which leads to an increase in intracellular cAMP concentration, works against the X-radiation influence.
Observations of Motor Reactions to Ions, Hormones, Pharmaceuticals, Electrical Stimulation and X Irradiation in Intraoperatively Removed Human Genital Preparations (Myometrium, Tuba Uterina and Genital Vessels)