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Behring Institute Mitteilungen (Behring Institute Research Communications) Issue No. 82, 'Advances in Diagnosis and Therapy' contains the following articles: Diagnostic and therapeutic trends in blood coagulation and fibrinolysis; Synthesis of biologically active deletion mutants of human factor VIII:C; Efficient expression system for human antithrombin III in baby hamster kidney cells; Synthesis of human factor XIIIa in bacterial cells; Factor XIII: enzymatic and clinical aspects; Isolation and expression of cDNA Coding for A new member of the phospholipase A2 inhibitor family; Recent advances in the biochemistry of the fibrinolytic system; Inactivation of AIDS-causing retroviruses by the manufacturing procedures for human plasma proteins; Anti-idiotypic antibodies: powerful tools in diagnosis and therapy; Human monoclonal anti-idiotypic antibodies as an epitope vaccine against pancreatic carcinoma; Investigations with monoclonal antibody drug (anthracycline) conjugates; Rodurubicin, a new tetraglycosidic anthracycline; 15-Deoxyspergualin: from cytostasis to immunosuppression; Similarities in function between pancreatic tumor cells and macrophages and their inhibition by murine monoclonal antibodies.