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Over the past twenty years, the mission of the Army Chemical Corps has evolved from a focus on protecting military forces against Chemical, Biological, Radiological, and Nuclear (CBRN) weapons to include the elimination Weapons of Mass Destruction (WMD), and CBRN consequence management. At the same time, an increased focus by both adversary state and nonstate actors on acquiring WMD has increased the potential for their use. Due to both increasing mission requirements and emerging threats, the Army must seek to implement policies and systems that provide a Chemical Force capable of responding to the full range of CBRN threats and hazards. With more than eighty percent of the Chemical Force residing in the Reserve Components (RCs), it is necessary to integrate the total force to optimize Chemical Force effectiveness. Integration has been challenged by the implementation of statutes and policies that have erected institutional barriers between the Regular Army (RA) and RCs. This paper analyzes potential challenges and identifies opportunities for increasing the responsiveness and effectiveness of the Army Chemical Corps through RA / RCs integration.