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The broader effects aerosols have on the earth and climate system is determined by a host of factors including their composition and vertical distribution. Characterizing the vertical distribution of clouds and aerosols is especially important considering it remains one of the greatest uncertainties in climate predictions. Space-based lidar, such as Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP) and Cloud-Aerosol Transport System (CATS), is especially well suited as a remote sensing tool in determining this vertical distribution. CALIOP has been used for over a decade to observe the global and vertical distribution of clouds and aerosols but is limited by Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations’ (CALIPSO’s) polar orbit to set equatorial crossing times of ~1:30AM/PM. This limited temporal sampling limits the use of CALIOP in determining the full diurnal variability of clouds and aerosols. On the International Space Station (ISS), with its inclined orbit and variable equatorial crossing times, the CATS lidar provided an opportunity to study the vertical profile of clouds and aerosols at a variety of local times. With this 33-month CATS record, we show that CATS captured the seasonal changes in global aerosol distributions and compares favorably with other instruments and models. Specifically targeting biomass burning regions, we also find CATS could observe the documented diurnal cycle in aerosol altitudes with some caveats. With the next generation of proposed space-based lidars including designs in similar orbits as the ISS and CATS, future studies of the aerosol diurnal and seasonal cycles would also be possible.