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Three boys, ages seven to 10, were diagnosed with nonfatal carbon monoxide (CO) poisoning following seven hours of participating in indoor motocross events. Indoor air testing, done after the incident, suggests that CO levels inside the facility could have reached potentially harmful levels, especially to susceptible populations. As shown by health outcome data, conditions at the facility posed an urgent public health hazard to the affected children. Due to mounting controversy, the owner has closed the facility. Owners and operators of indoor motorized sport arenas should evaluate adequacy of ventilation inside their structures, establish public-health-protective action levels for CO, and inform workers at, and users of, the facility about the hazards of exposure to CO.