Climate impacts on agriculture are of increasing concern in both the scientific and policy communities because of the need to ensure food security for a growing population. A special challenge is posed by the changes in the frequency and intensity of heat-waves, droughts, and episodic rainstorms already underway in many parts of the world. Changes in production are directly linked to such variations in temperature and precipitation during the growing season, and often to offseason changes in weather affecting soil-water storage and availability to crops. This is not an isolated problem but one of both global and regional importance, because of impacts on the livelihoods of smallholder farmers as well as consequences for the world food trade system. This two-part set the Agricultural Model Intercomparison and Improvement Project (AgMIP): Integrated Crop and Economic Assessments is the first to be entirely devoted to AgMIP (www.agmip.org). AgMIP is a major international research program focused on climate change and agriculture. The goal of the two parts is to advance the field by providing detailed information on new simulation techniques and assessments being conducted by this program. It presents information about new methods of global and regional integrated assessment, results from agricultural regions, and adaptation strategies for maintaining food security under changing climate conditions.