Structure Activity Relationships of Nuclear Receptor, GPCR and Kinase Modulators Revealed with Differential HDX (Englisch)
- Neue Suche nach: Griffin, Patrick
- Neue Suche nach: Griffin, Patrick
- Neue Suche nach: West, Graham
- Neue Suche nach: Chalmers, Michael
- Neue Suche nach: Landgraf, Rachelle
- Neue Suche nach: Zhang, Jun
In:
Biophysical journal
;
102
, 1
; 1a
;
2012
-
ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:Structure Activity Relationships of Nuclear Receptor, GPCR and Kinase Modulators Revealed with Differential HDX
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Beteiligte:
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Erschienen in:Biophysical journal ; 102, 1 ; 1a
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Verlag:
- Neue Suche nach: Biophysical Soc.
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Erscheinungsort:Bethesda, Md.
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Erscheinungsdatum:2012
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ISSN:
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ZDBID:
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Medientyp:Aufsatz (Zeitschrift)
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Format:Print
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Sprache:Englisch
- Neue Suche nach: 770/3800
- Neue Suche nach: 42.12
- Weitere Informationen zu Basisklassifikation
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Schlagwörter:
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Klassifikation:
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Datenquelle:
Inhaltsverzeichnis – Band 102, Ausgabe 1
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Rational Design of Potent Dimeric Ligands as Potential Theraputic Agents for Myotonic Dystrophy Type I (DM1)Jahromi, Amin H. et al. | 2012
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FRAP Analysis of Proteins Diffusion and Binding in Inhomogeneous MediaOrlova, Darya Yu. et al. | 2012
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Conjugation of Cholesterol to HIV-1 Fusion Inhibitor C34 Synergistically Potentiates Peptide-Membrane InteractionMatos, Pedro M. et al. | 2012
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Effects of Hidrophobic Surfactant Proteins SP-B and SP-C on the Mechanical Properties and Structural Stability of Phospholipid BilayersParra, Elisa et al. | 2012
-
Real-Time Imaging of Retrovirus-Endosome Fusion followed by Release and Trafficking of the Viral CorePadilla-Parra, Sergi et al. | 2012
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Sampling Issues in Atomistic Simulations of Peptides at Cyclohexane/Water and POPC/Water InterfacesSingh, Gurpreet et al. | 2012
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Wide-Field Time Resolved Anisotropy for In-Situ Lipid Phase DynamicsDadashvand, Neda et al. | 2012
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Electrostatic Effects on Model Bilayer Stability and StructureMarr, James M. et al. | 2012
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Probing Cell Nanoscale Structural Properties Using Intrinsic Contrast of Light ScatteringLiu, Yang et al. | 2012
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Shape Entropy and the Time Scales for Thermodynamics in Biological SystemsSalamon, Peter et al. | 2012
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Investigation of Lipid Distribution by Coherent Anti-Stokes Raman ScatteringItela, Lawrence O. et al. | 2012
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Molecular Basis for Immune Recognition of Exposed Phosphatidylserine via the Tim Family of ProteinsTietjen, Gregory T. et al. | 2012
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Exploring Hydrophobic Mismatch's Impacts on Dissociation of Gramicidin a Channels using Molecular Dynamics Free Energy SimulationsBeaven, Andrew H. et al. | 2012
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mAb10F5 is an Anti-Phospholipid Antibody that Binds in the Basal Ganglia in VivoKelly-Worden, Marie et al. | 2012
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PR3 Interacts Directly to Lipid Bilayers: Evidence from MD Simulations and SPR ExperimentsSchillinger, Anne-Sophie et al. | 2012
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Mg2+/Ca2+ Induced Changes in Structure, Dynamics and Stability of Dream ProteinPham, Khoa et al. | 2012
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Interaction with the Membrane Uncovers Essential Differences Between Highly Homologous GPCRsMondal, Sayan et al. | 2012
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Modulating Drug Effects of Metabotropic Glutamate Receptor 1 Alpha (mGluR1α) by Extracellular Ca2+Jiang, Yusheng et al. | 2012
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Intermediates of the Channel Rhodopsin PhotocycleRitter, Eglof et al. | 2012
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Molecular Dynamics Approach to Determine the Importance of an Asparagine Residue on Chloride-Dependence in the Human Serotonin TransporterZdravkovic, Igor et al. | 2012
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SecA alone can Promote Protein Translocation and Ion-Channel Activity: SecYEG Increases Efficiency and SpecificityHsieh, Ying-Hsin et al. | 2012
-
Dynamical Peptide Motions in MHC Groove is Crucial for Recognition and Activation of Certain T CellsKozono, Haruo et al. | 2012
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Simulated Block of Brain Na+ Channels by Ranolazine Predicts Selective Binding to Inactivated ConformationsKahlig, Kris M. et al. | 2012
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Initial Opening Steps of K+ Channels Probed by Extracellular Multivalent CationsArmstrong, Clay M. et al. | 2012
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QTc Interval is Prolonged in Hypercholesterolemic MiceLizotte, Éric et al. | 2012
-
Profile of the Late Sodium Current during Cardiac Action Potential in Guinea Pig Ventricular CardiomyocytesHorvath, Balazs et al. | 2012
-
Conformational Flexibility Mediates Resistance of HIV-1 Reverse Transcriptase to Nonucleoside InhibitorsDeredge, Daniel et al. | 2012
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Testing Models for the Slow Inactivated State using Unnatural Amino Acid MutagenesisValiyaveetil, Francis et al. | 2012
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Comparison of the Structure of a Bacterial Potassium Channel in Both 2D and 3D CrystalsDe Zorzi, Rita et al. | 2012
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Position of the Second Gating Charge along S4 in an Intermediate Conformation of a K+ Channel Voltage SensorLacroix, Jerome J. et al. | 2012
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Residues at the Outer Mouth of Kir1.1 Determine K-Dependent GatingSackin, Henry et al. | 2012
-
Quasi-In Vivo Electrocardiogram Measurement using Convolution of Field Potential Propagation in the On-Chip Cardiomyocytes Network CircuitNomura, Fumimasa et al. | 2012
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T-Tubule Morphology and Local Ca2+-Induced Ca2+ Release in Rat Ventricular Cardiomyocytes are Sensitive to Chronic Changes in Mechanical Load of the HeartKukadia, Punam et al. | 2012
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Separation and Accessibility of the Nucleotide-Binding Domain (NBD) Heterodimerization Interface When a CFTR Channel ClosesPoletto Chaves, Luiz A. et al. | 2012
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On the Coupling Mechanism of CFTR Gating by ATP HydrolysisJih, Kangyang et al. | 2012
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Three Charged Amino Acids in the Outer Vestibule of CFTR Stabilize the Open Pore ArchitectureCui, Guiying et al. | 2012
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Evolutionary and Mechanistic Insights into ABC ExportersGulyas-Kovacs, Attila et al. | 2012
-
Direct Quantification of the Effects of Osmolytes on Protein Unfolding and Refolding Pathways using AFM TechniquesBujalowski, Paul et al. | 2012
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Single Molecule FRET Measurements of Cardiac Troponin in Freely Diffusing AssembliesMoutsoglou, Maria E. et al. | 2012
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Conformational Changes in Troponin Within the Cardiac MyofilamentSun, Bing et al. | 2012
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Myosin Regulatory Light Chain Phosphorylation Rescues Cardiac Dysfunction Caused by Familial Hypertrophic Cardiomyopathy-Linked MutationsMuthu, Priya et al. | 2012
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Physiological Effects of FHC-Causing K104E Mutation in the Myosin Regulatory Light ChainHuang, Wenrui et al. | 2012
-
Power-Law Rheology of Normal and Cancer Cells Investigated by Atomic Force MicroscopyTakahashi, Ryosuke et al. | 2012
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Exploring Bundle Selectivity of Myosin X Forced Dimer Constructs in vivoJanik, Alicja et al. | 2012
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Interactions of Calmodulin and the IQ Motifs of a Type I Myosin in Fission YeastAlexander, Christopher J. et al. | 2012
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Single Molecule Measurement of the Myosin V Energy Transduction ProcessFujita, Keisuke et al. | 2012
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Voltage Dependent Anion Channel-3 (VDAC3) is the Major Isoform Contributing to Mitochondrial Metabolism in HepG2 Cells and is Regulated by Free Tubulin and ErastinMaldonado, Eduardo N. et al. | 2012
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Stepping Dynamics of Myosin Va Motors Physically-Linked through a Common Qdot-cargoAli, M. Yusuf et al. | 2012
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Energy Transduction by Bacterial Complexes IBatista, Ana P. et al. | 2012
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Suicide Inactivation in Rhodobacter Sphaeroides Cytochrome c Oxidase Lacking Subunit III Coincides with Release of CuB and Major Conformational Changes in Subunit IProchaska, Lawrence J. et al. | 2012
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The Adjacent Binding State Enables Myosin VI Dual FunctionIkezaki, Keigo et al. | 2012
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A Partially Structured Molten Globule ProteinReichenwallner, Joerg et al. | 2012
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Stochasticity in Action Potential duration Enhances Dispersion of Repolarisation at Fast Pacing RatesWalmsley, John et al. | 2012
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Intracellular Recording of Cardiomyocyte Action Potentials by Nanoelectrode ArraysLin, Carter (Ziliang) et al. | 2012
-
Study of Energetic Particle Induced Biological Effect through FTIR and Raman Micro-SpectroscopyHuang, Qing et al. | 2012
-
Specification, Construction, and Exact Reduction of Finite State Transition System Models of Biochemical ProcessesBugenhagen, Scott M. et al. | 2012
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Conducting Atomic Force Microscopy for Simultaneous Imaging of Structure and Ionic Current Through NanoporesMeckes, Brian et al. | 2012
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Cardiac Myosin Binding Protein C Phosphorylation in Human Cardiac Diseasevan der Velden, Jolanda et al. | 2012
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Finite-Element Model of the Silk Electrogelation ProcessKojic, Nikola et al. | 2012
-
Computational Free Energy Scale of Amino Acid Residues in Membrane Protein from Statistical MechanicsLin, Meishan et al. | 2012
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Membrane Protein Folding: Mechanistic and Kinetic ImplicationsBoechi, Leonardo et al. | 2012
-
DNA-Mediated Fusion Between Small Vesicles and a Planar, Tethered Bilayer PatchRawle, Robert J. et al. | 2012
-
Using Crosslinking and Mass Spectrometry to Study Glycine Receptor AllosteryDonelan, Chelsee A. et al. | 2012
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NMR Structure of VarI, a Novel Bioactive Peptide Toxin from Terebrid Marine SnailsBhuiyan, Mohammed et al. | 2012
-
An Ionic Switch in the Ligand-Binding Domain of Non-NMDA ReceptorsVijayan, Ranjit et al. | 2012
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Single Channel Studies and Kinetic Modeling of an Inactivation Deficient Voltage-Gated Sodium ChannelGoldschen-Ohm, Marcel P. et al. | 2012
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Post-Translational Modifications of Myofilament Proteins Involved in Length-Dependent Prolongation of Relaxation in Rabbit Right Ventricular MyocardiumMonasky, Michelle M. et al. | 2012
-
Tracking Image Cross-Correlation for Elucidating the Fusion Process of VirusesDupont, Aurélie et al. | 2012
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Crossing the Entropic Barrier to Coupled Folding and BindingBorcherds, Wade M. et al. | 2012
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Conformational Ensembles of Intrinsically Disordered Proteins are Determined by Charge PatterningDas, Rahul K. et al. | 2012
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On the Role of CBS Domains in Osmoregulatory ABC TransportersPoolman, Bert et al. | 2012
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The Relationship Between the Number of Residues in the Dynamics and Stability of the A-Beta Amyloid, a Molecular Dynamics StudyHaddadian, Esmael J. et al. | 2012
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A Systematic Computational Method to Predict and Enhance Antibody-Antigen Binding in the Absence of Antibody Crystal StructuresXu, Jianqing et al. | 2012
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Sequence and Structure Dependent DNA-DNA InteractionsXia, Qi et al. | 2012
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Molecular Dynamics Investigations on Base Sequence Specificity of Counterion Binding to DNAAtzori, Alessio et al. | 2012
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Analyzing DNA Packaging Initiation of Bacteriophage T4 by a Real-Time Single Molecule Fluorescence AssayVafabakhsh, Reza et al. | 2012
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Improved Parametrization of Ion-DNA Interactions for MD Simulations of Dense DNA SystemsYoo, Jejoong et al. | 2012
-
Thumbs Down: Subdomain Rearrangements in the Drug Bound HIV-1 Reverse TranscriptaseWright, David W. et al. | 2012
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Translating Bulk Measures of Capsid Assembly Progress into Insights on Fine-Scale Kinetics and PathwaysSmith, Gregory R. et al. | 2012
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Uncoating of Mature HIV Capsids Driven by Reverse TranscriptionRouzina, Ioulia et al. | 2012
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The Nature of Constitutive Activation of HER2 at the Single Molecule LevelChung, Inhee et al. | 2012
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Activation of the Innate Immune Receptor Dectin-1 by ClusteringFitieh, Amira et al. | 2012
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Integrating Single Molecule Techniques to Investigate Antigen-Independent Effects of IgE Binding to FcεRISchwartz, Samantha L. et al. | 2012
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Dynamics of the Dopamine Transporter in Various States in the Presence of an Explicit Sodium GradientMerchant, Bonnie A. et al. | 2012
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Transport Cycle of Mitochondrial Carriers from Internal SymmetriesEnkavi, Giray et al. | 2012
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Human Epidermis as a Model System for the Investigation of Intracellular Signaling Pathways, In SituCursons, Joseph et al. | 2012
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CD40 Ligand Deficiency Attenuates Angiotensin II Induced Oxidative Stress and Endothelial Dysfunction in a Murine Model of Arterial HypertensionHausding, Michael et al. | 2012
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A Validated Computational Model of Cardiac Pacemaking: Mechanisms of Physiological and Pharmacological Rate ModulationSeveri, Stefano et al. | 2012
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Contribution of Calcium Waves to the Regulation of Beating Rhythm in Sinoatrial Node CellsHamada, Hiroyuki et al. | 2012
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State-Dependent FRET Reports Large Gating-Ring Motions in BK ChannelsMiranda, Pablo et al. | 2012
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BK and CaV Channel Interactions in the Plasma MembraneSavalli, Nicoletta et al. | 2012
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Yellow Optogenetics with Volvox Channelrhodopsin VariantsSchneider, Franziska et al. | 2012
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Construction of Topologically Complex Patient-Specific Cubic Hermite Meshes for the Cardiac Electrophysiology ProblemGonzales, Matt et al. | 2012
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A Three-Ion Selectivity Filter Potential Energy Landscape of a Putative Open-Conductive KcsAMedovoy, David et al. | 2012
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Analysis of Multichannel Signals using a Channel SimulatorPalacio, Luis A. et al. | 2012
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Pore Helix-S6 Interactions are Critical in Governing KCNQ3 AmplitudesChoveau, Frank S. et al. | 2012
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Novel Roles of Kinesin-8 in Organizing Mitotic SpindlesSu, Xiaolei et al. | 2012
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Cooperative Dynamics of mDia1 and Arp2/3 in Basal Epithelial Cell MigrationLee, Kwonmoo et al. | 2012
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Model of Condensation of an Actomyosin Network into a Contractile Ring for Fission Yeast Cell Division: The Effect of Actin Cross-Linkers Alpha-Actinin and FimbrinOjkic, Nikola et al. | 2012
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Long Distance Lipid: Protein Coupling in the Protein TransloconBondar, Ana-Nicoleta et al. | 2012
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Structure-Based Models to Understand the Cipher that Governs Tale Protein Affinity with DNA.Anand, Priya et al. | 2012
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Quantification of Calcium Pump Structure Changes in Live CelssHou, Zhanjia et al. | 2012
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Triggered Gene Expression in Fed-Vesicle Microreactors with a Multifunctional MembraneDanelon, Christophe et al. | 2012
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Microwave Sensor for Measuring the Growth of BiomaterialsBassey, Christopher E. et al. | 2012
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Single-Molecule In Vitro and Live-Cell Studies of Allostery through DNAChong, Shasha et al. | 2012
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Remote Control of DNA-Acting Enzymes by Molecular Boundary ConditionsBai, Hua et al. | 2012
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Frustrated Differentiation of Mesenchymal Stem Cell Cultured on Microelastically-Patterned Photocurable Gelatinous GelsKidoaki, Satoru et al. | 2012
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Engineered Microenvironments to Study Mechanisms of Tissue Tropism in MetastasisDandley, Erinn et al. | 2012
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Kinetic Equivalence of pH Difference (ΔPh) and Electrical Potential (Δψ) across Membrane in ATP Synthesis by Bacillus PS3 FOF1-ATP SynthaseSoga, Naoki et al. | 2012
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Detection of Single Actin Filaments at Fluorescence Interference Contrast CheckpointsLard, Mercy et al. | 2012
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Direct Electron-Beam Nanopatterning of Teflon AF Surfaces for Site-Selective Formation of Molecular Phospholipid FilmsShaali, Mehrnaz et al. | 2012
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Conventional and Accelerated Molecular Dynamics Simulations of Staphylococcus Aureus Sortase AKappel, Kalli et al. | 2012
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Mechanochemistry of Small Molecules: Into Which Bond does the Force Go?Li, Wenjin et al. | 2012
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Ligand-Protein Interaction Studied by Computer Simulation and Time-Resolved X-Ray CrystallographyTsuduki, Takayuki et al. | 2012
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Nucleosome Detection using Solid State NanoporesSoni, Gautam et al. | 2012
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The Molecular Basis of Cluster Formation by Membrane-Bound Lipidated RasGorfe, Alemayehu A. et al. | 2012
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Spatiotemporal Image Correlation Spectroscopy Reveals Arp2/3-Complex-Driven Cytoplasmic Streaming in Mouse Oocytes, Maintaining Meiotic Cortical Spindle PositioningUnruh, Jay R. et al. | 2012
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Stochastic Properties of Transcription Factor Expression Revealed by Single-Molecule Noise AnalysisXiao, Jie et al. | 2012
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A Simple, Versatile Method for GFP-Based Single Molecule Localization MicroscopyRies, Jonas et al. | 2012
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Docking of PKC(Alpha)-C1 and PKC(Beta)-C2 Domains to POPC/POPS/POG Lipid MembranesAlwarawrah, Mohammad et al. | 2012
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Membrane Properties Involved in Calcium-Stimulated Microparticle Release from the Plasma Membranes of S49 Lymphoma CellsBell, John D. et al. | 2012
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Investigation into the Role of Phosphatidylserine in Modifying the Susceptibility of Human Lymphocytes to Secretory Phospholipase A2 using Cells Deficient in the Expression of Scramblase.Nelson, Jennifer et al. | 2012
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Molecular Interactions and Membrane Targeting of Granuphilin C2 Domains: A Preliminary StudyLiakhova, Tatyana et al. | 2012
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Phosphoinositides Alter Lipid Bilayer PropertiesRusinova, Radda et al. | 2012
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Statins Modify Lipid Bilayer PropertiesSanford, R. Lea et al. | 2012
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Influence of the Membrane Composition of Retinal Photoreceptors on the Reversible Binding of a Neuronal Calcium Sensor Protein (NCS), Recoverin : A Solid-State NMR and FTIR StudyValois-Paillard, Geneviève et al. | 2012
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Sequence-Specific Control of ETS Transcription FactorsPoon, Gregory M. et al. | 2012
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Effects of Melatonin on Lipid Membrane Induced Aggregation of Amyloid BetaChoi, Youngjik(Vince) et al. | 2012
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The High-Resolution Structures of Two Piscidin Isoforms in Two Microbial Lipid Membrane Mimics Using Solid-State NMRHayden, Robert M. et al. | 2012
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Calcium Ion Controlled Nanoparticle Induced Tubulation in Supported Flat Phospholipid VesiclesGozen, Irep et al. | 2012
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Vesicle-Membrane Fusion is Enhanced by Cholesterol and Low TemperatureWoodbury, Dixon J. et al. | 2012
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Characterizing the Interactions of Lipid Bilayers with Antimicrobial Peptide and Phospholipase A2Wang, Jinghui et al. | 2012
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Mapping GABAA Receptor Single Nucleotide Polymorphisms (SNPs) Linked to Epilepsy: Insights into the Receptor Gating and AssemblyHernandez, Ciria C. et al. | 2012
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A Chemical Chaperone Attenuates Pressure-Overload Induced Cardiac Hypertrophy by Reducing ER StressSik Park, Chang et al. | 2012
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Synchronization of Local Calcium Releases by Beta-Adrenergic Stimulation in Cardiac Pacemaker CellsMonfredi, Oliver et al. | 2012
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Non-Cholinergic Acute Sympathetic Stress Enhances Electrical Coupling in the Mouse Adrenal MedullaHill, Jacqueline et al. | 2012
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Spatial-Temporal Dynamics of Collective ChemosensingSun, Bo et al. | 2012
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Direct Penetration of Cell-Penetrating Peptides Across Lipid BilayersWang, Andrew et al. | 2012
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Type a Bax Channels: Electrophysiological PropertiesLin, Shang H. et al. | 2012
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Investigation of the Self-Association of δ-Lysin Variants via Fluorescence AnisotropyAblan, Francis Dean O. et al. | 2012
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Calcium Handling Properties in a Hibernating Animal: Insights into Antiarrhythmic MechanismsXie, Lai-Hua et al. | 2012
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Pore Width of Disease-Causing Connexin26 Containing ChannelsHarris, Andrew L. et al. | 2012
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A Model of the Open Pore MscL Based on Experimental Data and Restrained Coarse Grained SimulationsDeplazes, Evelyne et al. | 2012
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Piezo1 Gating: Comparison Between Whole Cell Currents and the PatchGottlieb, Philip et al. | 2012
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Nuclear Transport of Paxillin Depends on Myosin ContractionSathe, Aneesh R. et al. | 2012
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New Estimates for the ‘Allosteric’ Constant of Neuromuscular Acetylcholine Receptor-ChannelsNayak, Tapan K. et al. | 2012
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Voltage-Gated Calcium Channel α2δ Subunits in Lipid Rafts: The Importance of Proteolytic Cleavage Into α2 and δKadurin, Ivan et al. | 2012
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TRIP8B Allosterically Regulates the Ability of cAMP to Enhance the HCN2 Channel OpeningHu, Lei et al. | 2012
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Generation and Characterization of a Polyclonal Antibody Specific for the Extracellular Loop of CaV2.1 Voltage-Gated Ca2+ ChannelsLi, Shuyang et al. | 2012
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The Dynamics of Protein-Protein Interactions Between Cytoplasmic Domains in MscLIscla, Irene R. et al. | 2012
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DPP6A Confers Redox Sensitivity to Kv4 Channel InactivationJerng, Henry H. et al. | 2012
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Sodium 3-Hydroxyolean-12-en-30-Oate is a Novel and Selective Activator of β1 Subunit-Containing BK Channels and thus Cerebral Artery DilatorBukiya, Anna N. et al. | 2012
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The CRAC Motif Nearest to the N-End of Slo1 Cytosolic C-Tail is the Main Determinant of BK Channel Sensitivity to Membrane CholesterolSingh, Aditya K. et al. | 2012
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A Model of β1-Adrenergic Regulation of L-Type Ca2+ Current and Ryanodine Receptors in Mouse Ventricular MyocytesShorina, Maria V. et al. | 2012
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Modulation of Cav2.2 Channels via Activation of Human GABAB Receptors Expressed in HEK293 Cells by Analgesic α-ConotoxinsHuynh, Thuan G. et al. | 2012
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Oxygen Increases Heart Injury in Ischemia/ReperfusionBopassa, Jean C. et al. | 2012
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Visualization, Modeling, and Spatial Statistics of Mitochondrial Assembly in Adult Cardiomyocytes using Serial Block-Face Scanning Electron MicroscopyYan, Jenny et al. | 2012
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O-Glcnacylation in the Long Isoform of ZASP in Human Heart MuscleChing Leung, Man et al. | 2012
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Molecular Mechanism of Enhancement of CaV1.2 Channels by β2-Adrenergic ReceptorsJuergens, Jeffery T. et al. | 2012
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Biochemical Diversity of Human Skeletal MuscleTirrell, Timothy F. et al. | 2012
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Functional and Structural Impact of Site-Directed Methionine Oxidation in MyosinMoen, Rebecca J. et al. | 2012
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Variable T-Tubule Density and Organization in Rat Atrial CardiomyocytesFrisk, Michael et al. | 2012
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Altered Action Potential Heterogeneity in Hypertrophic Right Ventricles of RatsHardy, Matthew E.L. et al. | 2012
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Elevated Plasma Oxidized Lipids in Severe Pulmonary Hypertension are Fully Restored by Estrogen TherapyUmar, Soban et al. | 2012
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The Growth of Bacterial ColoniesWarren, Mya et al. | 2012
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Modeling the Dynamics of Escherichia Coli Populations through Spectroscopy and Particle TrackingWalsman, Jason M. et al. | 2012
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Aging's Effect on Physical Performance and Single Muscle Fiber Contractility in a Nonhuman Primate ModelChoi, SeungJun et al. | 2012
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Efficient Intrinsic Photoprotection in Strongly Coupled (Bacterio) Chloropyll ComplexesSavikhin, Sergei et al. | 2012
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Conserved Surface Residues of Tropomyosin are Required for Cooperative Activation of Actin by MyosinBarua, Bipasha et al. | 2012
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Oxidized Heme - A Novel Inhibitor of Calcium-Dependent BK Channel in Rat Brain MitochondriaAugustynek, Bartlomiej et al. | 2012
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Charge Burial Energetics and Protein pKa Shifts Modeled with Nonlocal ElectrostaticsBardhan, Jaydeep P. et al. | 2012
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Highly Parallel Magnetic Tweezers for the Study of DNA-Protein InteractionsBurnham, Daniel R. et al. | 2012
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The Effect of Lipid Mediated Attraction and Antigen Affinity on B-Cell Receptor Microcluster FormationYu-Yang, Paul et al. | 2012
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Pathway Commons at Virtual Cell: Use of Pathway Data For Mathematical ModelingBlinov, Michael L. et al. | 2012
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Novel Metaheuristic-Based Approach for Solving Transmembrane Assembly using Limited Distance InformationSujaree, Kanon et al. | 2012
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Partial Reconstruction of Biological Networks from Perturbation ExperimentsArtyomov, Maxim et al. | 2012
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How to Find Non Hub Important Nodes in Protein Networks?Grolmusz, Vince et al. | 2012
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Myosin-Induced Detachment Causes Differences Between Ensemble and Single Molecule Myosin KineticsWalcott, Sam et al. | 2012
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Dynamics and Multiple Binding Modes of DNA Intercalators Revealed by Single-Molecule Force SpectroscopyPaik, Daniel H. et al. | 2012
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Quantification of Protein Concentration using Single Molecule Western BlotYoung Ryu, Ji et al. | 2012
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Single-Image Axial Localization Precision Analysis for Individual FluorophoresDeSantis, Michael C. et al. | 2012
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Measuring Cell Mechanics by Optical Alignment Deformation SpectroscopyRoth, Kevin B. et al. | 2012
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Single-Cell Biopsy using NanopipettesActis, Paolo et al. | 2012
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Photoswitchable Dendrimer Nanoconjugates as Fluorescent Probes for Super-Resolution MicroscopyKim, Younghoon et al. | 2012
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Separation of NADPH and NADH Fluorescence Emission in Live Cells using FlimBlacker, Tom S. et al. | 2012
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Phasor Analysis with a New Widefield Photon-Counting Flim DetectorColyer, Ryan A. et al. | 2012
-
Multiphoton Ultraviolet Microscopy Reveals Dopamine Dynamics in Live Brain TissueSarkar, Bidyut et al. | 2012
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Fluorescence Lifetime Imaging Microcopy of Extravasating Cancer Cells in the Mouse MicroenvironmentDigman, Michelle A. et al. | 2012
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Ionic Liquids Transport through Single NanoporesGamble, Trevor et al. | 2012
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Using FCS to Study Protein Disorder and AggregationRhoades, Elizabeth et al. | 2012
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Building a Community of Practice: Lessons from the Biophysical Society's Summer Short CourseRussellMcKenzie, Elisabeth J. et al. | 2012
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Fluorescence Fluctuation Spectroscopy Applied to Cell-Free Expression, Chromophore Maturation and Protein-DNA InteractionMacdonald, Patrick J. et al. | 2012
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Insights into RyRs Dysfunctions via Studies of Intracellular Calcium SignalsKyrychenko, Sergii et al. | 2012
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Optical Recordings of Ca2+ Influx via TRPV4 and Voltage-Gated L-type Ca2+ Channels in Arterial Smooth MuscleSantana, Luis F. et al. | 2012
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Single Molecule Fluorescence Study of the B. Thuringiensis Toxin Cry1Aa Reveals TetramerizationMcGuire, Hugo et al. | 2012
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A Multi Scale Approach for Path Sampling: Applications to PeptidesFujisaki, Hiroshi et al. | 2012
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Live Cell Super-Resolution Imaging of Transverse Membrane Tubules in Heart FailureWagner, Eva et al. | 2012
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Superresolution and Single Molecule Imaging of Transcription by Reflected Light Sheet MicroscopyGebhardt, J. Christof M. et al. | 2012
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STED - AFM: Tip Probing Enhanced by Super Resolved TargetingChacko, Jenu V. et al. | 2012
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Bayesian Modeling of Crystallographic DisorderFenn, Timothy et al. | 2012
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Conformational Selection and Allosteric Regulation upon Ligand Binding in G-Protein Coupled ReceptorsNiesen, Michiel J.M. et al. | 2012
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Role of Cytoplasmic Buffers in Spatial H+-Ca2+ Interactions in Ventricular MyocytesSwietach, Pawel et al. | 2012
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Super-Resolution Fluorescence Microscopy of Transcription Sites in E. ColiFinan, Kieran R. et al. | 2012
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Identification of a Small Molecule-Ligand-Binding Pocket in a G Protein-Coupled Receptor using Genetically-Encoded PhotocrosslinkersGrunbeck, Amy et al. | 2012
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Quantitative Dissection of RNA Polymerase-Promoter Interactions using Protein Beacon AssayMekler, Vladimir et al. | 2012
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Dynamic Formation of a Ternary PTH Receptor-Arrestin-GS Complex: Consequences for Cell SignalingWehbi, Vanessa L. et al. | 2012
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Cholesterol Flip-Flop Dynamics in a Phospholipid Bilayer: All Atom Molecular Dynamics SimulationsChoubey, Amit et al. | 2012
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Computational Study of Self-Aggregation and Interaction of Amyloidgenic Peptide Oligomers with a Lipid BilayerHuynh, Loan K. et al. | 2012
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Tracking Conformational Changes during Amyloidogenesis in Real-Time at Atomic-Resolution by NMRBrender, Jeffrey R. et al. | 2012
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A Statistical Mechanical Approach to Protein AggregationSchreck, John et al. | 2012
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Oxidative Modification of Alpha-Synuclein Modifies its CytotoxicityFalomir-Lockhart, Lisandro J. et al. | 2012
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Shedding Light on Single MoleculesBlock, Steven et al. | 2012
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Phosphatidylinositol 4,5-Bisphosphate (PIP2) Controls Magnesium Gatekeeper TRPM6 ActivityXie, Jia et al. | 2012
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Ganglion-Specific Splicing of TRPV1 Underlies Infrared Sensation in Vampire BatsGracheva, Elena O. et al. | 2012
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Structure Function Analysis of Innexin ShakingB(Lethal)DePriest, Adam D. et al. | 2012
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Effects of Meclofenamate Sodium on Proteasome Activity in Cardiac CellsMichelle Hwang, Soyun et al. | 2012
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Enzymatic Characterization and Spectroscopic Studies of Diarylethene Modified LysozymeInada, Taeko et al. | 2012
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Monitoring Dimerization of GpA using FRETBinder, Jennifer K. et al. | 2012
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The Allosteric Modulation of Syntaxin 1A by Munc18: Characterization of the Open and Closed Conformations of SyntaxinDawidowski, Damian et al. | 2012
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Origin of Cooperative Relaxation in Polymeric Solids and an Allosteric AssemblyRitz-Gold, Caroline J. et al. | 2012
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Shaken, Not Stirred: Collapsing a Peptoid Monolayer to Produce Free-Floating, Stable NanosheetsSanii, Babak et al. | 2012
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Structure and Dynamics of Membrane-Associated Hepatitis C Virus Protein P7 by NMR SpectroscopyCook, Gabriel A. et al. | 2012
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Solid-State NMR Studies on the Membrane Bound Acylated Peptide Hormone GhrelinVortmeier, Gerrit et al. | 2012
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Initial Structural Studies of Mtb Membrane Protein “CrgA” in Membrane Mimetic EnvironmentDas, Nabanita et al. | 2012
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Single Molecule FRET Studies of the DNA Mismatch Repair Protein MutSα using Specific Labeling with Unnatural Amino AcidsSacho, Elizabeth J. et al. | 2012
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tRNA Annealing onto the HIV-1 Genome Studied by FRET Spectroscopy and MicroscopyJepsen, Mette et al. | 2012
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Nanoscale Imaging of the Piezoelectric Effect of Bilayer Phospholipid Molecules of Cell Membrane using Piezoresponse Force Microscopy∗Cheng, Qian et al. | 2012
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RNA Biophysics in Living Cells using Shape ChemistryTyrrell, Jillian et al. | 2012
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Substrate Specificity and Dynamic Instability of RAD51-Filament Assembly on Single- and Double-Stranded DNACandelli, Andrea et al. | 2012
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Single Molecule Studies of Bacterial Transcription Coupled RepairHo Wan, Kevin et al. | 2012
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Mechanisms of Eukaryotic Transcription InitiationTomko, Eric J. et al. | 2012
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Impact of Macromolecular Crowding on DNA ReplicationAkabayov, Barak et al. | 2012
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Cholesterol-Lipid Affinity Determined by EPRWilliams, Justin A. et al. | 2012
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Body Mechanics Regulate the Force Threshold for Gentle Touch Sensation in the Nematode C. ElegansPetzold, Bryan C. et al. | 2012
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Role of Disorder in Clathrin Lattice AssemblyLafer, Eileen M. et al. | 2012
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Local Cell Membrane Stiffness and Viscosity Mapped by Thermal Noise ImagingHsu, Yunhsiang et al. | 2012
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Caffeine Treatment and Depolarization Alter the Spatial and Temporal Characteristics of Calcium Sparks on Intact Amphibian Skeletal MuscleVincze, János et al. | 2012
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Effect of Oxidative Stress on Intracellular Ca2+ and Na+ Concentration in Duchenne Muscular Dystrophy MyotubesPerez, Claudio F. et al. | 2012
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Using Full Factorial Design of Experiments on an Automated Patch Clamp Instrument: A Case Study on the Ionworks Quattro and Nav1.5 ChannelLee, Yan T. et al. | 2012
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Dynamics of Calcium Uptake and Release by the Mitochondria in the HeartBoyman, Liron et al. | 2012
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Histamine-Evoked Signaling in Human Primary KeratinocytesThe, Lydia et al. | 2012
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Gating Pore Currents Reveal Sliding Helix Motion of S4 Gating Charges during Activation of NaChBacGamal El-Din, Tamer M. et al. | 2012
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Coordination of Bending and Wedging in Membrane FissionAkimov, Sergey A. et al. | 2012
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Ligand-Binding Characteristics of the Cyclic Nucleotide Binding Domain (CNBD) of the HERG Potassium Channel and Long QT SyndromeZheng, Renjian et al. | 2012
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Quantitative FRAP Analysis Demonstrates that Raft Protein Clustering Alters N-Ras Depalmitoylation, Membrane Interactions and Activation PatternEisenberg, Sharon et al. | 2012
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Activation of TRPV1 by a Recombinant Double-Knot Toxin from a Chinese Bird SpiderLadt, Kelsey C. et al. | 2012
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Conformational Change Involved in Gating of Acid Sensing Ion Channel (ASIC1a)Ramaswamy, Swarna S. et al. | 2012
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Nanoscale Interactions of Lipids and Proteins in Live Cell Membranes Revealed by STED NanoscopyHonigmann, Alf et al. | 2012
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Subtype Specific Activation of P2X Receptors by Free and Magnesium-Bound ATPLi, Mufeng et al. | 2012
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Pore and Gating Properties of TRPM3 IsoformsVriens, Joris et al. | 2012
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Direct Permeation of the P2X7 Receptor Pore by Nanometer MoleculesBrowne, Liam E. et al. | 2012
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Characterization of the Role of PKC-Theta in the Modulation of ClC-1 Chloride Channel Function and Calcium Homeostasis in Fast- and Slow-Twitch Skeletal Muscle by using PKC-Theta Null MicePierno, Sabata et al. | 2012
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Inhibition of a Dimer Interface Mutant of CLC-0 by Intracellular Cadmium IonYu, Yawei et al. | 2012
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Current and Selectivity in a Model Sodium Channel under Physiological ConditionsGillespie, Dirk et al. | 2012
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Structural and Functional Characterization of a Bacterial K+ TransporterPan, Yaping et al. | 2012
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Ion Channel Remodeling in Failing and Non-Failing Hearts of Inherited DCM Mouse Model -Usefulness of Running Wheel in Detection of Heart Failure-Sugihara, Masami et al. | 2012
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Non-Contact Microrheology of Monolayers and MembranesShlomovitz, Roie et al. | 2012
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Role of Triadin in the Organization of Reticulum Membrane at the Muscle TriadFourest-Lieuvin, Anne et al. | 2012
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The Changes of [Ca2+] in Sr and Ca2+ Release Flux during Fatiguing Activation of Mouse Skeletal Muscle FibersManno, Carlo et al. | 2012
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The Motor Domain Transducer is Key in Kinesin Functional PlasticityRichard, Jessica et al. | 2012
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Expression of Recombinant Beta-Actin in the High-Density Insect Cell CultureOhki, Takashi et al. | 2012
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Structural Dynamics of the Actin-Binding Domains in Dystrophin and UtrophinLin, Yun et al. | 2012
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Casein Kinase 2 Reverses Tail-Independent Inactivation of Kinesin-1Xu, Jing et al. | 2012
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Electron Crystallography Reveals a Possible Motion Mechanism for the Voltage Sensor Domains in MembranesShi, Liang et al. | 2012
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In Vitro Study of the Direct Effect of Microtubule Acetylation and Detyrosination on Kinesin MotilityKaul, Neha et al. | 2012
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3D Tracking of Cellular Nanoscale Dynamics with Sub-Millisecond Temporal ResolutionJuette, Manuel F. et al. | 2012
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Accelerating the Rate of Convergence of Umbrella Sampling Simulations in Lipid BilayersNeale, Chris et al. | 2012
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A Nano-Scavenger in Action: The Molecular Mechanism of Membrane Cholesterol Extraction by CyclodextrinsLopez, Cesar A. et al. | 2012
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Fluorogen Activating Peptides that Enhance Photostability through Encapsulation of the FluorogenSaurabh, Saumya et al. | 2012
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Protonation and the Matrix Effect of Oleate Vesicles, a Coarse Grained Molecular Dynamics Studyvan Hoof, Bram et al. | 2012
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Pore Gating of K+ Channels Studied by Essential Dynamics Simulations using the Simplified Bacterial K+ Channel KcsALinder, Tobias et al. | 2012
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Auger Spectrum of a Water Molecule after Single and Double Core-Ionization by Intense X-Ray RadiationInhester, Ludger et al. | 2012
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Three-Dimensional Ultrastructure of Micrometer Thick Cellular Subvolumes by STEM TomographySousa, Alioscka A. et al. | 2012
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A Hybrid Tirf-Magnetic Tweezers Instrument for Studying Sub-Nanometer Effects of Force on ProteinsLeachman, Samuel M. et al. | 2012
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Super-Resolution Study of the Dynamics and Spatial Distribution of Ribosomes in Live E. Coli CellsBakshi, Somenath et al. | 2012
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Probing the Molecular Architecture and Assembly of Synthetic and Fungal Melanins with Solid-State NMRChatterjee, Subhasish et al. | 2012
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Hydration-Mediated Slow Dynamics in Phospholipid MembranesMolugu, Trivikram R. et al. | 2012
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3D Imaging of Nanoscopic Membrane Systems Regulating Cardiac Excitation-Contraction Coupling: Multi-Color Optical Super-Resolution and Serial Block-Face Scanning Electron MicroscopyWong, Joseph Isaac S. et al. | 2012
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Pixel-Wise Fitting: Noise-Free Analytical 3D Visualisation of Calcium Handling in Cardiac MyocytesTian, Qinghai et al. | 2012
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EPR Spectroscopic Distance Measurements of the KCNE1 Membrane Protein in Micelles and Lipid BilayersSahu, Indra D. et al. | 2012
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Temperature Dependent FCS Shows Mammalian Cell Membrane is not Poised near Miscibility Transition TemperatureLee, Il-Hyung et al. | 2012
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Studying Fusion of Influenza to Supported Lipid Bilayers using Individual Virion Imaging TechniquesCostello, Deirdre A. et al. | 2012
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Nanometer Resolution of Cav-Generated Ca2+ GradientsTadross, Michael R. et al. | 2012
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Probing the Structure of Membrane Proteins with ESEEM and DEER Pulsed EPR TechniquesLorigan, Gary A. et al. | 2012