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This article describes the implementation of a Gateway device in a mobile phone for ECG Signal transmission between an acquisition device and a Data Reception Centre (DRC). The Gateway device is embedded in an ECG monitoring system called Holtin (Intelligent Holter) that includes three basic devices: Front-End, Gateway and DRC; and two wireless technologies: Bluetooth and GPRS. The implementation is done in a Nokia 3650 mobile, which has all the functionalities needed for the application. The system works as follows: The Front-end acquires the ECG signal and sends it, using Bluetooth, to the Gateway, who encapsulates and sends it to the DRC through Internet (TCP/IP protocol) over GPRS wireless technology. The system can be configured to acquire one or three ECG leads and to work in two possible operation modes: continuous monitoring or by events. The application has been developed in separate modules in order to achieve design simplicity, easiness in the exploitation and reusability.