Erscheinungsjahr
Medientyp
Format
Lizenz
Sprache
Synonyme wurden verwendet für: Chemistry
Suche ohne Synonyme: journal:(Journal of Medicinal Chemistry)
Verwendete Synonyme:
- allgemeine chemie
- chemie
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Development of a 1,2,4-Triazole-Based Lead Tankyrase Inhibitor: Part II
Freier ZugriffAmerican Chemical Society | 2021| -
Phosphonate inhibitors of West Nile virus NS2B/NS3 protease
Freier ZugriffTaylor & Francis Verlag | 2019| -
Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells
Freier ZugriffAmerican Chemical Society | 2022| -
Synthetic Peptides That Antagonize the Angiotensin-Converting Enzyme‑2 (ACE-2) Interaction with SARS-CoV‑2 Receptor Binding Spike Protein
Freier ZugriffAmerican Chemical Society | 2022| -
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology
Freier ZugriffAmerican Chemical Society | 2022| -
Synthesis and anti-rheumatoid arthritis activities of 3-(4-aminophenyl)-coumarin derivatives
Freier ZugriffTaylor & Francis Verlag | 2021| -
Structure–Activity Relationship of para-Carborane Selective Estrogen Receptor β Agonists
Freier ZugriffAmerican Chemical Society | 2021| -
An AGT-based protein-tag system for the labelling and surface immobilization of enzymes on E. coli outer membrane
Freier ZugriffTaylor & Francis Verlag | 2019| -
The chemical diversity and structure-based discovery of allosteric modulators for the PIF-pocket of protein kinase PDK1
Freier ZugriffTaylor & Francis Verlag | 2019| -
Activation of carbonic anhydrase isoforms involved in modulation of emotional memory and cognitive disorders with histamine agonists, antagonists and derivatives
Freier ZugriffTaylor & Francis Verlag | 2021| -
Sulphonamide inhibition profile of Staphylococcus aureus β-carbonic anhydrase
Freier ZugriffTaylor & Francis Verlag | 2020| -
Discovery of 3-alkyl-5-aryl-1-pyrimidyl-1H-pyrazole derivatives as a novel selective inhibitor scaffold of JNK3
Freier ZugriffTaylor & Francis Verlag | 2020| -
Combining carbonic anhydrase and thioredoxin reductase inhibitory motifs within a single molecule dramatically increases its cytotoxicity
Freier ZugriffTaylor & Francis Verlag | 2020| -
Hydroxypropyl-β-cyclodextrin as an effective carrier of curcumin – piperine nutraceutical system with improved enzyme inhibition properties
Freier ZugriffTaylor & Francis Verlag | 2020| -
Toward Raman Subcellular Imaging of Endothelial Dysfunction
Freier ZugriffAmerican Chemical Society | 2021| -
1,3,4-Oxadiazole-naphthalene hybrids as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative activity, apoptotic effect, and in silico studies
Freier ZugriffTaylor & Francis Verlag | 2022| -
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors
Freier ZugriffTaylor & Francis Verlag | 2019| -
Discovery of ACH-000143: A Novel Potent and Peripherally Preferred Melatonin Receptor Agonist that Reduces Liver Triglycerides and Steatosis in Diet-Induced Obese Rats
Freier ZugriffAmerican Chemical Society | 2021| -
Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling
Freier ZugriffAmerican Chemical Society | 2021| -
2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases
Freier ZugriffTaylor & Francis Verlag | 2022| -
Synthesis and bioactivities evaluation of oleanolic acid oxime ester derivatives as α-glucosidase and α-amylase inhibitors
Freier ZugriffTaylor & Francis Verlag | 2022| -
Unveiling the interaction profile of rosmarinic acid and its bioactive substructures with serum albumin
Freier ZugriffTaylor & Francis Verlag | 2020| -
In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N1,N3-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide
Freier ZugriffTaylor & Francis Verlag | 2019| -
Inhibition of African swine fever virus protease by myricetin and myricitrin
Freier ZugriffTaylor & Francis Verlag | 2020| -
A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors
Freier ZugriffTaylor & Francis Verlag | 2020| -
Tackling Antimicrobial Resistance with Small Molecules Targeting LsrK: Challenges and Opportunities
Freier ZugriffAmerican Chemical Society | 2020| -
Phytochemical profile, enzyme inhibition activity and molecular docking analysis of Feijoa sellowiana O. Berg
Freier ZugriffTaylor & Francis Verlag | 2021| -
Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates
Freier ZugriffAmerican Chemical Society | 2021| -
Soyasaponins from Zolfino bean as aldose reductase differential inhibitors
Freier ZugriffTaylor & Francis Verlag | 2019| -
Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae
Freier ZugriffTaylor & Francis Verlag | 2022| -
Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect
Freier ZugriffTaylor & Francis Verlag | 2021| -
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis
Freier ZugriffAmerican Chemical Society | 2021| -
Anticancer sulfonamide hybrids that inhibit bladder cancer cells growth and migration as tubulin polymerisation inhibitors
Freier ZugriffTaylor & Francis Verlag | 2019| -
Synthesis and biological evaluation of novel 8-substituted quinoline-2-carboxamides as carbonic anhydrase inhibitors
Freier ZugriffTaylor & Francis Verlag | 2019| -
Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones
Freier ZugriffTaylor & Francis Verlag | 2019| -
In vitro anti-TB properties, in silico target validation, molecular docking and dynamics studies of substituted 1,2,4-oxadiazole analogues against Mycobacterium tuberculosis
Freier ZugriffTaylor & Francis Verlag | 2021| -
Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors
Freier ZugriffTaylor & Francis Verlag | 2021| -
From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis
Freier ZugriffAmerican Chemical Society | 2021| -
Inhibitory evaluation of Curculigo latifolia on α-glucosidase, DPP (IV) and in vitro studies in antidiabetic with molecular docking relevance to type 2 diabetes mellitus
Freier ZugriffTaylor & Francis Verlag | 2021| -
Optimization of Truncated Glucagon Peptides to Achieve Selective, High Potency, Full Antagonists
Freier ZugriffAmerican Chemical Society | 2021| -
Development of an In Silico Prediction Model for P‑glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration
Freier ZugriffAmerican Chemical Society | 2021| -
Design and Evaluation of Peptide Dual-Agonists of GLP‑1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and Emesis
Freier ZugriffAmerican Chemical Society | 2021| -
Inhibition studies of bacterial α-carbonic anhydrases with phenols
Freier ZugriffTaylor & Francis Verlag | 2022| -
Osteopontin – a biomarker of disease, but also of stage stratification of the functional myocardial contractile deficit by chronic ischaemic heart disease
Freier ZugriffTaylor & Francis Verlag | 2019| -
Phosphonamidates are the first phosphorus-based zinc binding motif to show inhibition of β-class carbonic anhydrases from bacteria, fungi, and protozoa
Freier ZugriffTaylor & Francis Verlag | 2020| -
Enhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer
Freier ZugriffAmerican Chemical Society | 2021| -
α/β-Hydrolase Domain (ABHD) Inhibitors as New Potential Therapeutic Options against Lipid-Related Diseases
Freier ZugriffAmerican Chemical Society | 2021| -
Fibrate-based N-acylsulphonamides targeting carbonic anhydrases: synthesis, biochemical evaluation, and docking studies
Freier ZugriffTaylor & Francis Verlag | 2019|
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