Proposal for a new ethical scheme addressing the use of laboratory animals for biomedical purposes (Englisch)
- Neue Suche nach: Delpire, V. C.
- Neue Suche nach: Mepham, T. B.
- Neue Suche nach: Balls, M.
- Neue Suche nach: Delpire, V. C.
- Neue Suche nach: Mepham, T. B.
- Neue Suche nach: Balls, M.
- Neue Suche nach: Zeller, A.-M. v.
- Neue Suche nach: Halder, M. E.
- Neue Suche nach: Balls, M.
In:
Alternatives and animal use in the life sciences; Progress in the reduction, refinement, and replacement of animal experimentation
;
841-852
;
2000
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ISBN:
- Aufsatz (Konferenz) / Print
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Titel:Proposal for a new ethical scheme addressing the use of laboratory animals for biomedical purposes
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Beteiligte:Delpire, V. C. ( Autor:in ) / Mepham, T. B. ( Autor:in ) / Balls, M. ( Autor:in ) / Zeller, A.-M. v. / Halder, M. E. / Balls, M.
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Kongress:World congress; 3rd, Alternatives and animal use in the life sciences; Progress in the reduction, refinement, and replacement of animal experimentation ; 1999 ; Bologna, Italy
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Erschienen in:DEVELOPMENTS IN ANIMAL AND VETERINARY SCIENCES ; 31b ; 841-852
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Verlag:
- Neue Suche nach: Elsevier
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Erscheinungsort:Amsterdam , Oxford
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Erscheinungsdatum:01.01.2000
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Format / Umfang:12 pages
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ISBN:
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Medientyp:Aufsatz (Konferenz)
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Format:Print
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Sprache:Englisch
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Schlagwörter:
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Datenquelle:
© Metadata Copyright the British Library Board and other contributors. All rights reserved.
Inhaltsverzeichnis Konferenzband
Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
- 3
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The European Commission's work in relation to the replacement, reduction and refinement of animal experimentationRichardson, H. et al. | 2000
- 7
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Forty years onRussell, W. M. S. et al. | 2000
- 15
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Declaration of Bologna| 2000
- 23
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A proposal to amend the Declaration of HelsinkiMenache, A. et al. | 2000
- 27
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Would Sisyphus meet the challenges of validation from test development to global regulatory acceptance?Spielmann, H. et al. | 2000
- 39
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Replacing animals in medical researchLangley, G. et al. | 2000
- 51
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Replacement, reduction and refinement and biologicals: about facts, fiction and frustrationsHendriksen, C. F. M. et al. | 2000
- 65
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Learning from refinement strategies applied at low and high levels of noxiousnessMellor, D. et al. | 2000
- 79
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Alternatives in the teaching of biology at secondary and university levels: an ongoing success storyRussell, G. K. et al. | 2000
- 93
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Session summaryAgapakis-Causse, C. et al. | 2000
- 97
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In vitro (photo)genotoxicity testing: a task involving multiple end-pointsAgapakis-Causse, C. et al. | 2000
- 107
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Transformation of Syrian hamster embryo (SHE) cells: a biologically relevant and accurate predictor of chemical carcinogenicityLeBoeuf, R. / Aardema, M. / Gibson, D. / Isfort, R. et al. | 2000
- 113
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Current strategies for detecting carcinogens by using genetic toxicity testsZeiger, E. et al. | 2000
- 127
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Using hepatic cell lines for drug metabolism studies?Jover, R. / Bort, R. / Gomez-Lechon, M. J. / Castell, J. V. et al. | 2000
- 139
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Building a biotechnology platform for metabolism studies in pharmacology and toxicologyDoehmer, J. / Krebsfanger, N. / Schober, W. / Luch, A. / Buters, J. T. M. / Jacob, J. / Seidel, A. / Murdter, T. / Zanger, U. M. / Eichelbaum, M. et al. | 2000
- 147
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The integrated use of a genetically engineered cell line panel harbouring drug metabolising enzymes to detect metabolism-related problem compoundsCoecke, S. / Catalani, P. / Bull, S. / Langezaal, I. / Bogni, A. / Bremer, S. / Balls, M. et al. | 2000
- 159
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Long-term culture of rat hepatocytes and prevention of oxidative stress by addition of high concentrations of pyruvate to the culture mediumAsiru, O. / Vanhaecke, T. / Vercruysse, A. / Rogiers, V. et al. | 2000
- 177
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Toxicogenomics: application of genomics to toxicological sciencesKimber, I. / Pennie, W. D. et al. | 2000
- 185
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Toxicogenomics: DNA microarrays in toxicity testing and mechanistic studiesPennie, W. D. / Brooks, A. N. et al. | 2000
- 193
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Molecular mechanisms underlying the effects of chronic exposure to addictive drugsRomualdi, P. / Capobianco, A. et al. | 2000
- 203
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Embryonic stem cell technology: loss of function/gain of function assays and developmental analysis of teratogenic factors in vitroWobus, A. M. / Guan, K. / Rohwedel, J. et al. | 2000
- 215
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The culture of mouse embryoid bodiesDesbaillets, I. / Ziegler, U. / Groscurth, P. / Gassmann, M. et al. | 2000
- 231
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Development of human renal and hepatic co-culture in vitro systems for immunotoxicity testing: an overview of available co-culture methodsVan Gompel, J. et al. | 2000
- 237
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Reconstructed human skin: alternative models for the safety and efficacy assessment of dermato-cosmetological productsSchmidt, R. / Duval, C. / Regnier, M. et al. | 2000
- 241
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Evaluation of aggregating brain cell cultures as a model for studying ischaemia-related neurodegenerative processesPardo, B. / Honegger, P. et al. | 2000
- 249
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Co-cultures: mimicry of cellular interactions within a tissue and between organs - consequences for toxicity testingMaier, P. / Milosevic, N. / Bruinik, A. et al. | 2000
- 263
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Prediction of barrier penetration in drug discoveryGarberg, P. / Lindmark, T. / Lundgren, B. et al. | 2000
- 271
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A comparison of Madin-Darby canine kidney cells and bovine brain endothelial cells as a blood-brain barrier screen in early drug discoveryPolli, J. W. / Humphreys, J. E. / Wring, S. A. / Burnette, T. C. / Read, K. D. / Hersey, A. / Butina, D. / Bertolotti, L. / Pugnaghi, F. / Serabjit-Singh, C. J. et al. | 2000
- 291
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Renal transepithelial resistance (TER) and paracellular permeability (PCP) are reliable endpoints to screen for nephrotoxicityPfaller, W. / Troppmair, E. et al. | 2000
- 305
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A human conjunctival model for the evaluation of eye irritantsWard, S. / Walker, T. / Trocme, S. / Hallberg, C. / Kruszewski, F. / DiPasquale, L. et al. | 2000
- 323
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EN ISO 10993 series of standards: in vitro and in vivo biocompatibility testing of medical devicesDannhorn, D. R. et al. | 2000
- 329
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Designing biofunctionality assays to test biomaterials in vitroKirkpatrick, C. J. et al. | 2000
- 339
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Improved detection of pyrogenic substances on polymer surfaces with an ex vivo human whole blood assay in comparison to the Limulus amoebocyte lysate testPetri, E. / van de Ploeg, A. / Habermaier, B. / Fennrich, S. et al. | 2000
- 349
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Cultured rat myocytes as an in vitro model for muscle irritancy of intramuscular drug formulationsEdwards, C. N. / Svendsen, O. et al. | 2000
- 359
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Prevalidation: successes justify the conceptCurren, R. D. / Southee, J. A. et al. | 2000
- 365
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Validation in practice - from theory to realityFentem, J. H. et al. | 2000
- 375
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Is it good enough? Objective assessment of toxicity test method performance in validation studiesBruner, L. H. / Carr, G. J. / Curren, R. D. et al. | 2000
- 385
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The role of the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) in the evaluation of new toxicological testing methodsStokes, W. / Hill, R. et al. | 2000
- 395
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Validation in practice - the reality for skin sensitisationBasketter, D. / Gerberick, F. / Kimber, I. et al. | 2000
- 407
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The principles of replacement, reduction and refinement applied to the regulation of chemicalsEvans, P. et al. | 2000
- 415
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Validation and acceptance of alternative test methods in Europe: the ECVAM principles for promoting new methods to regulatory acceptanceLiebsch, M. et al. | 2000
- 425
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The first method evaluation by the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM): the murine local lymph node assay (LLNA)Sailstad, D. / Hattan, D. / Hill, R. / Stokes, W. et al. | 2000
- 435
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Regulatory acceptance and implementation of new testing methods: an FDA perspectiveWilcox, N. L. et al. | 2000
- 449
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Principles of toxicity prediction from chemical structureBarratt, M. D. et al. | 2000
- 457
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Structure activity relationship methods applied to chemical toxicity: making better use of what we haveRichard, A. M. / Bruce, R. / Greenberg, M. et al. | 2000
- 469
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Structure-activity relationships in mutagenesis and carcinogenesisBenigni, R. et al. | 2000
- 479
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Embedded cluster modelling: a novel quantitative structure-activity relationship method for generating elliptic models of biological activityWorth, A. P. / Cronin, M. T. D. et al. | 2000
- 493
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Validation and development of the DEREK skin sensitisation rulebase by analysis of the BgVV List of contact allergensBarratt, M. / Langowski, J. et al. | 2000
- 513
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Worms (Tubifex tubifex) and partition coefficients for estimation of acute toxicityTichy, M. / Borek-Dohalsky, V. / Rucki, M. et al. | 2000
- 525
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An integrated approach to the prediction of systemic toxicity by using biokinetic models and biological in vitro test methodsBlaauboer, B. J. / Forsby, A. / Houston, J. B. / Beckman, M. / Combes, R. D. / DeJongh, J. et al. | 2000
- 537
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Global cellular response as an indicator of carcinogenic potential of xenobioticsHrelia, P. / Nusse, M. / Fimognari, C. et al. | 2000
- 545
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Evaluation of the phototoxic potential of chemically modified tetracyclines with the 3T3 neutral red uptake phototoxicity testZerler, B. / Roemer, E. / Raabe, H. / Sizemore, A. / Reeves, A. / Harbell, J. et al. | 2000
- 561
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Skin corrosion and irritation - toward complete replacementBotham, P. et al. | 2000
- 567
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The current status and perspectives on alternatives for regulatory eye irritancy testingEsdaile, D. J. et al. | 2000
- 571
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Two validation programmes for alternative methods to the rabbit eye irritation test in JapanKato, S. et al. | 2000
- 587
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The use of clinical data to confirm the safety of consumer products for use on the skinStitzel, K. A. et al. | 2000
- 593
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Isolated pig ears: an in vitro model for screening for irritant chemicals by using stimulation of trans-epidermal water loss (TEWL) as the test parameterElliott, G. / van den Eeden, S. / Poot, C. / Bruijnzeel, P. et al. | 2000
- 601
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Screening of skin irritants by RNA detection as a viability marker in porcine organotypic skin explantsJacobs, J. J. L. / Lehe, C. / Cammans, K. D. A. / Das, P. K. / Elliott, G. R. et al. | 2000
- 613
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Skin sensitisation: immunological mechanisms and novel approaches to predictive testingKimber, I. et al. | 2000
- 623
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Dendritic cell stimulation by allergensGerberick, G. F. / Hulette, B. / Ryan, C. A. et al. | 2000
- 635
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A strategy for the prediction of skin sensitisation: an alternative to animal testingRousset, F. / Verda, D. / Arrighi, J.-F. / Peguet-Navarro, J. / Cottin, M. et al. | 2000
- 643
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Selective induction of keratinocyte cytokines by chemical allergensCorsini, E. / Galli, C. L. et al. | 2000
- 653
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Specific enhanced release of interleukin-8 and interleukin-1alpha in reconstructed human epidermis in vitro after stimulation with different classes of skin irritants and contact sensitisersCoquette, A. / Berna, N. / Vandenbosch, A. / Poumay, Y. et al. | 2000
- 671
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Haematotoxicology in drug development: a model of human toxicologyGribaldo, L. et al. | 2000
- 679
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Method development for a prevalidation study of the in vitro GM-CFU assay for predicting myelotoxicityPessina, A. / Albella, B. / Bueren, J. / Brantom, P. / Casati, S. / Corrao, G. / Gribaldo, L. / Parchment, R. / Parent-Massin, D. / Piccirillo, M. et al. | 2000
- 693
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Oncology clinical trials and in vitro prediction models for xenobiotic toxicologyParchment, R. E. et al. | 2000
- 709
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Relevance of clonogenic assays in food haematotoxicologyParent-Massin, D. et al. | 2000
- 721
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Reduction, model development and efficient experimental designFesting, M. F. W. et al. | 2000
- 729
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Engineering to reduce animal numbersTrajstman, A. C. et al. | 2000
- 737
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Reduced animal use in efficacy testing in disease models with use of sequential experimental designsWaterton, J. C. / Middleton, B. J. / Pickford, R. / Allott, C. P. / Checkley, D. / Keith, R. et al. | 2000
- 753
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Common errors in the statistical analysis of experimental dataFesting, M. F. W. et al. | 2000
- 759
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Improving data analysis: new aspects in toxicity testing using time-to-event dataMeister, R. et al. | 2000
- 773
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Analysis of behavioural sequences: refinement of statistical methods to reduce animal use in the life sciencesPuopolo, M. / Chiarotti, F. et al. | 2000
- 783
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A review of reduction and refinement of regulatory toxicity studies for pharmaceuticalsTweats, D. et al. | 2000
- 793
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The use of dogs as second species in the regulatory testing of pesticidesGerbracht, U. / Spielmann, H. et al. | 2000
- 799
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Reduction of animal use in regulatory testing of biologicalsDobbelaer, R. et al. | 2000
- 809
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Evaluation of the relevance of the target animal safety testCussler, K. / van der Kamp, M. D. O. / Poessnecker, A. et al. | 2000
- 821
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Cost-benefit assessment: the United Kingdom experienceRichmond, J. et al. | 2000
- 829
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Cost and animal use reduction analysis: review of the National Toxicology Program 14-day toxicity study databaseChhabra, R. S. / Haseman, J. K. / Bucher, J. R. et al. | 2000
- 835
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The concepts of "severe suffering" of experimental animals and "essential needs of man and animal" as used in cost-benefit analysesStafleu, F. / Vorstenbosch, J. / Tramper, R. / de Jong, M. / Eckelboom, E. / Krijger, F. et al. | 2000
- 841
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Proposal for a new ethical scheme addressing the use of laboratory animals for biomedical purposesDelpire, V. C. / Mepham, T. B. / Balls, M. et al. | 2000
- 857
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A review of common misconceptions associated with the in vivo ascites and in vitro production of monoclonal antibodiesMcArdle, J. et al. | 2000
- 865
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Chicken egg yolk IgY - an alternative to mammalian antibodiesChilov, D. / Camenisch, G. / Tini, M. / Spielmann, P. / Gassmann, M. et al. | 2000
- 873
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Recombinant antibodies by phage display: the end of animal use?Stadler, B. M. / Vogel, M. / Miescher, S. et al. | 2000
- 879
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Production of antibody fragments by lower eukaryotic micro-organismsde Geus, B. / Harmsen, M. / van der Linden, R. / Verrips, T. et al. | 2000
- 891
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The OECD guidance document on humane endpoints for experimental animals used in safety evaluation studiesKoeter, H. B. W. M. / Goldberg, A. M. et al. | 2000
- 897
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Humane endpoints for laboratory animals used in toxicity testingStokes, W. S. et al. | 2000
- 907
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The use of humane endpoints in acute oral toxicity testingSchlede, E. / Gerner, I. / Diener, W. et al. | 2000
- 915
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Possibilities for the use of humane endpoints in vaccine potency testsCussler, K. / Morton, D. B. / Hendriksen, C. F. M. et al. | 2000
- 933
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In vivo testing in the production of human vaccines: a critical overviewDescamps, J. / Duchene, M. et al. | 2000
- 941
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Eliminating vaccine testing in animals - more action, less talkLucken, R. et al. | 2000
- 945
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USDA initiatives for reducing in vivo testing of inactivated veterinary vaccinesLudemann, L. R. et al. | 2000
- 951
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Detection of vaccine contamination by chicken anaemia virus by the polymerase chain reactionFalcone, E. / Tarantino, M. / Massi, P. / Di Pasquale, I. / Vignolo, E. / Tollis, M. et al. | 2000
- 959
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Development of an in vitro potency test for inactivated Newcastle disease vaccinesMaas, R. / de Winter, M. / Koch, G. / Oei, H. / Bongers, J. et al. | 2000
- 969
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In vitro approaches for estimating activity of tetanus toxin as an alternative assay for specific toxicitySesardic, D. / Corran, P. H. / Gee, C. / Ekong, T. A. N. et al. | 2000
- 979
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What's in a name? The meaning of the term "potency", as applied to immunobiologicals for human use, and its implications for alternatives and validationArciniega, J. L. et al. | 2000
- 987
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Validation of potency tests for veterinary vaccinesBruckner, L. et al. | 2000
- 991
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Prevalidation of an alternative to the rabbit pyrogen test based on human whole bloodHartung, T. / Fennrich, S. / Fischer, M. / Montag-Lessing, T. / Wendel, A. et al. | 2000
- 1001
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An in vitro assay for testing of neutralising antibodies to botulinum toxinsSesardic, D. / Martin, H. / Tierney, R. / Bigalke, H. et al. | 2000
- 1013
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Adverse effects: regulation and classification in Europede Greeve, P. et al. | 2000
- 1023
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The New Zealand regulatory approach to the use of live animals in research, testing and teachingBayvel, A. C. D. et al. | 2000
- 1033
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Regulation and classification of the use of animals for scientific purposes in AustraliaBaker, R. M. et al. | 2000
- 1039
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Regulation and classification of adverse effects in the United StatesStephens, M. L. et al. | 2000
- 1049
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Practical applications of animal harm scales: international perspectivesOrlans, F. B. et al. | 2000
- 1057
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Global harmonisation of pain and distress classification systems: current analysis and opportunity for changePurves, K. E. et al. | 2000
- 1075
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Public policies on assessing and reporting degrees of animal harm: international perspectivesOrlans, F. B. et al. | 2000
- 1083
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Adverse effects - recognition and assessment, and humane endpointsMorton, D. B. / Ambrose, N. / Leach, M. C. / Poirier, G. et al. | 2000
- 1095
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Adverse effects of transgenesis in farm animalsHazekamp, A. A. H. / de Cock Buning, T. et al. | 2000
- 1107
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Quantitative assessment of welfare in experimental animals: the development and use of scoring systemsLloyd, M. H. / Wolfensohn, S. / Thornton, P. et al. | 2000
- 1119
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Observation of signs of ill-health in laboratory animals - the animal technician's point of viewHirsjarvi, P. / Liesirova, L. / Harlin, I. et al. | 2000
- 1127
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Assessment of pain in rodents by using standard laboratory techniques: an ethological perspective aimed at reducing sufferingCirulli, F. / De Acetis, L. / Alleva, E. et al. | 2000
- 1137
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A practical framework for refining experimental proceduresHartley, P. / Burton, N. et al. | 2000
- 1145
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Effective treatment of post-operative pain: overcoming the obstacles to managing surgical pain in laboratory animalsKaras, A. Z. et al. | 2000
- 1151
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Refinement of laboratory animal anaesthesiaFlecknell, P. et al. | 2000
- 1159
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Refinement of euthanasiaAmbrose, N. / Wadham, J. / Morton, D. et al. | 2000
- 1175
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Echocardiography in laboratory dogs: a method of refinement for the assessment of cardiovascular toxicologyHanton, G. / Baneux, P. et al. | 2000
- 1187
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The use of telemetry to refine experimental techniqueEinstein, R. / Rowan, C. / Billing, R. / Lavidis, N. et al. | 2000
- 1199
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Approaches to low invasive acquisition of physiological data from unrestrained animalsCook, C. / Ingram, J. / Harris, P. et al. | 2000
- 1213
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Refinement in behavioural researchMench, J. et al. | 2000
- 1221
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Refinement in research for wildlife conservationKirkwood, J. K. et al. | 2000
- 1229
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Refinement in behavioural research: a statistical approachChiarotti, F. / Puopolo, M. et al. | 2000
- 1239
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Unobtrusive study of animals in the wild: database search strategiesFirestein, K. / Hart, L. et al. | 2000
- 1251
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Environmental enrichment: a right of rodents!Baumans, V. et al. | 2000
- 1257
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Advancing rabbit and rodent housing and husbandry researchHubrecht, R. et al. | 2000
- 1269
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Refinement in rabbit housing and husbandryStauffacher, M. et al. | 2000
- 1283
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Environmental enrichment to improve animal welfare: goals, methods, and measures of successFraser, D. / Jasper, J. / Weary, D. M. et al. | 2000
- 1295
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Environmental enrichment for non-human primates: an experimental approachDe Rosa, C. / Vitale, A. / Puopolo, M. et al. | 2000
- 1305
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The qualitative assessment of animal behavioural expression and its application to animal husbandryWemelsfelder, F. et al. | 2000
- 1313
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Refinements in laboratory bird husbandryHawkins, P. et al. | 2000
- 1323
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An ethical rationale for why students should not be permitted to harm or kill animalsOrlans, F. B. et al. | 2000
- 1333
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A model for the education of attitudes toward the use of laboratory animalsNab, J. / Cappetti, C. et al. | 2000
- 1343
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A global overview of law and policy concerning animal use in educationBalcombe, J. et al. | 2000
- 1351
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Teaching objectives in higher education - can they be met by alternatives to animals?Hughes, I. E. et al. | 2000
- 1361
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Electronic alternatives to using animals for learning veterinary anatomyDavies, A. et al. | 2000
- 1365
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Multimedia ethologyAmbrose, N. / Poirier, G. / Morton, D. B. et al. | 2000
- 1375
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Education and training on the Three Rs: requirements and implementationvan Zutphen, B. / Blom, H. J. M. et al. | 2000
- 1383
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Obstacles to acceptance and implementation of the Three Rs by scientistsZurlo, J. et al. | 2000
- 1389
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Outreach to scientists on the Three Rs in Australia and New Zealand - the role of ANZCCARTBaker, R. M. et al. | 2000
- 1395
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Promotion of alternative methods in Latin America and the Caribbean: challenges and hopesPerez, L. U. / Murillo, G. et al. | 2000
- 1401
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Three Rs information needs of scientistsBottrill, K. et al. | 2000
- 1409
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Facilitating compliance in bibliographic searching for alternatives: a model programme for developing local supportHart, L. A. / Wood, M. W. et al. | 2000
- 1415
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A multi-media training program for biomedical researchers: working with laboratory animalsDuffee, N. E. / Fallon, M. T. / Laber, K. E. et al. | 2000
- 1429
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The risk of rhetoric in presenting the Three RsTerzariol, L. / Ruzzier, F. et al. | 2000
- 1433
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The use of alternatives within secondary and tertiary education: differing priorities and strategiesMiles, J. et al. | 2000
- 1441
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The Internet's impact on the Three RsBoschert, K. et al. | 2000
- 1449
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How can societies decide whether or not the transgenesis of laboratory animals should be permitted?Reiss, M. J. et al. | 2000
- 1457
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Genetic engineering: is there a moral issue?de Cock Buning, T. et al. | 2000
- 1465
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An ethical framework for the use of transgenic mice in basic researchPoirier, G. M. C. / Morton, D. B. et al. | 2000
- 1475
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Judging transgenic projects: what should be known?Cohen, N. E. / Hazekamp, A. A. H. / de Cock Buning, T. et al. | 2000
- 1487
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Ethical review in the UK: a requirement for a process, not a committeeMoore, G. et al. | 2000
- 1495
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Processes and outcomes of animal ethics committees: a review of the Australian experienceRose, M. et al. | 2000
- 1505
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Governmental review and decision making in ethics: a study of the working practices of the Dutch National Committee on Animal BiotechnologyPaula, L. / de Cock Buning, T. et al. | 2000
- 1519
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The constitution of Institutional Animal Care and Use Committees: a principled approachVorstenbosch, J. et al. | 2000
- 1533
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How useful are animal models?Matfield, M. et al. | 2000
- 1541
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Evaluation of animal model researchShapiro, K. J. et al. | 2000
- 1553
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Field studies and animal models: the possibility of misleading inferencesBekoff, M. et al. | 2000
- 1563
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Conflicts between Human Rights and Animal Rights are InevitableBalls, M. et al. | 2000
- 1565
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The conflicting structure of rights in the human/non-human relationshipTallacchini, M. et al. | 2000
- 1571
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Are conflicts between human rights and animal rights inevitable?Westra, L. et al. | 2000
- 1575
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All Laboratory Animal Use could be Ended by the Year 2020 Moderator's summaryMorton, D. B. et al. | 2000
- 1577
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Could all laboratory animal use could be ended by the year 2020?Matfield, M. et al. | 2000
- 1581
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All laboratory animal use could be ended by the year 2020?Wilkins, D. et al. | 2000
- 1583
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The Zero Option should be Adopted for Non-human Primates Moderator's summaryStephens, M. L. et al. | 2000
- 1587
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Moving toward the zero option for the use of non-human primates as laboratory animalsBalls, M. et al. | 2000
- 1593
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Non-human primates must remain accessible for vital biomedical researchHau, J. / Farah, I. O. / Carlsson, H.-E. / Hagelin, J. et al. | 2000
- 1603
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Routine Testing for Endocrine Disrupters will Merely Provide Data which Cannot be Interpreted Moderator's summaryBalls, M. et al. | 2000
- 1605
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Hormonally-active substances in the environment: introduction and state of knowledgeGreim, H. A. et al. | 2000
- 1611
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Will routine testing of endocrine disrupturs merely provide data which cannot be interpreted? (Abstract)Shelby, M. et al. | 2000
- 1615
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Human Tissue: A Good and Ethical Alternative?van der Valk, J. / Anderson, R. / Lenzi, P. et al. | 2000
- 1621
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The Use of BiomarkersBottrill, K. / Bonassi, S. / Lenaz, G. et al. | 2000
- 1625
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Acute Toxicity Testing In VitroEkwall, B. / Fry, J. et al. | 2000
- 1631
-
Chronic Toxicity Testing In VitroVericat, J.-A. / Hanley, A. B. et al. | 2000
- 1639
-
High Production Volume (HPV) Chemical TestingGoldberg, A. M. / Spielmann, H. et al. | 2000
- 1643
-
The In Vitro Testing of Medical DevicesCervinka, M. / Dannhorn, D. et al. | 2000
- 1647
-
The Use of Human Volunteers in TestingBasketter, D. A. / Menache, A. et al. | 2000
- 1651
-
Good Laboratory Practice and In Vitro ToxicologyCoecke, S. / Cooper-Hannan, R. / Harbell, J. et al. | 2000
- 1655
-
The Standardisation of Cell Culture ProceduresHartung, T. / Gstraunthaler, G. et al. | 2000
- 1659
-
Progress on the Sharing of Proprietary Information for the Validation of Alternative MethodsStitzel, K. A. / Todd, M. H. et al. | 2000
- 1665
-
Collaboration as the Way to the Acceptance of Alternative Methodsde Silva, O. / Loprieno, N. et al. | 2000
- 1673
-
The Worldwide Acceptance of Validated Test MethodsBagley, D. / Milstien, J. et al. | 2000
- 1677
-
The Development of New Vaccines Without Using AnimalsHendriksen, C. F. M. / Gupta, R. et al. | 2000
- 1681
-
Escaping from the Use of Freund's Complete AdjuvantLindblad, E. B. / Hau, J. et al. | 2000
- 1687
-
Non-Statistical Experimental Design as an Aid to RefinementFry, D. / Morton, D. B. et al. | 2000
- 1691
-
Multidisciplinary Team Development and Laboratory Animal CareBaneux, P. / Townsend, P. et al. | 2000
- 1693
-
Update on Refinement GuidelinesGriffin, G. / Koeter, H. B. W. M. et al. | 2000
- 1697
-
Update on Policies of Journalsvan Zutphen, B. / Festing, M. F. W. et al. | 2000
- 1701
-
The Need for a Refinement JournalFlecknell, P. / Gruber, F. P. et al. | 2000
- 1705
-
Harmonising IACUC practicesJennings, M. / Miller, J. et al. | 2000
- 1713
-
The Role of National PlatformsRogiers, V. / de Greeve, P. / Garthoff, B. et al. | 2000
- 1719
-
Welfare Aspects of TransgenesisCosta, P. et al. | 2000
- 1725
-
Should Cats and Dogs be used as Laboratory Animals?Baker, R. / Broadhead, C. et al. | 2000
- 1731
-
Alternative Method Databases - Specialised Information Sources on Alternatives to Support Scientists and Authorities Resposible for Granting Project LicencesJanusch-Roi, A. / Libowitz, L. / Grune, B. / Kreger, M. et al. | 2000
- 1737
-
Key Words for Use with AlternativesBottrill, K. / Huggins, J. et al. | 2000
- 1741
-
Replacement Alternatives in TeachingDewhurst, D. / Davies, A. et al. | 2000
- 1749
-
Reflections on the pastClark, D. G. et al. | 2000
- 1753
-
Future directionsGoldberg, A. M. et al. | 2000
- 1759
-
The Three Rs in the post-genome areavan Zutphen, B. et al. | 2000
- 1763
-
The reduction, refinement and replacement of laboratory animal procedures - a look to the futureBalls, M. et al. | 2000