A DR5-dependent synthetic lethal relationship between Myc overexpression and GSK3beta/FBW7 loss of function (Englisch)
- Neue Suche nach: Rottmann, S.
- Neue Suche nach: Wang, Y.
- Neue Suche nach: Nasoff, M.
- Neue Suche nach: Deveraux, Q. L.
- Neue Suche nach: Quon, K. C.
- Neue Suche nach: Cold Spring Harbor Laboratory
- Neue Suche nach: Rottmann, S.
- Neue Suche nach: Wang, Y.
- Neue Suche nach: Nasoff, M.
- Neue Suche nach: Deveraux, Q. L.
- Neue Suche nach: Quon, K. C.
- Neue Suche nach: Stewart, D. J.
- Neue Suche nach: Stillman, B.
- Neue Suche nach: Cold Spring Harbor Laboratory
In:
Cold Spring Harbor Symposium on quantitative biology; Molecular approaches to controlling cancer
;
222
;
2004
-
ISBN:
- Aufsatz (Konferenz) / Print
-
Titel:A DR5-dependent synthetic lethal relationship between Myc overexpression and GSK3beta/FBW7 loss of function
-
Beteiligte:Rottmann, S. ( Autor:in ) / Wang, Y. ( Autor:in ) / Nasoff, M. ( Autor:in ) / Deveraux, Q. L. ( Autor:in ) / Quon, K. C. ( Autor:in ) / Stewart, D. J. / Stillman, B. / Cold Spring Harbor Laboratory
-
Kongress:70th, Cold Spring Harbor Symposium on quantitative biology; Molecular approaches to controlling cancer ; 2005
-
Erschienen in:
-
Verlag:
- Neue Suche nach: Cold Spring Harbor Laboratory,
-
Erscheinungsort:Cold Spring Harbor, N.Y.:
-
Erscheinungsdatum:01.01.2004
-
Format / Umfang:222 pages
-
ISBN:
-
Medientyp:Aufsatz (Konferenz)
-
Format:Print
-
Sprache:Englisch
-
Schlagwörter:
-
Datenquelle:
© Metadata Copyright the British Library Board and other contributors. All rights reserved.
Inhaltsverzeichnis Konferenzband
Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
- 1
-
Oncogenes and the future of cancer therapyVarmus, H. / Cold Spring Harbor Laboratory et al. | 2004
- 2
-
Microenvironmental regulators of tissue structure and tumor progression-The role of matrix metalloproteinases in the loss of tissue polarity and induction of genomic instabilityBissell, M. J. / Kenny, P. A. / Werb, Z. / Radisky, D. / Cold Spring Harbor Laboratory et al. | 2004
- 3
-
CTLA-4 blockade in tumor immunotherapyAllison, J. P. / Cold Spring Harbor Laboratory et al. | 2004
- 4
-
Searching for a specific contribution by loss of BRCA1 function to breast cancerGanesan, S. / Richardson, A. / Wang, C. / De Nicolo, A. / Silver, D. / Lu, X. / ElShamy, W. / Greenberg, R. / Sobhian, B. / Drapkin, R. et al. | 2004
- 5
-
DNA damage response pathways in cancer causation and treatmentKastan, M. B. / Kitagawa, R. / Takagi, M. / Bakkenist, C. J. / Cold Spring Harbor Laboratory et al. | 2004
- 6
-
BRCA2 function in the repair of DNA double-strand breaksPavletich, N. / Cold Spring Harbor Laboratory et al. | 2004
- 7
-
Apoptotic signaling pathways of the p53 familyPrives, C. / Baptiste, N. / Poyurovsky, M. / Ohkubo, S. / Tanaka, T. / Urist, M. / Cold Spring Harbor Laboratory et al. | 2004
- 8
-
Therapeutic exploitation of the DNA repair defect in BRCA mutant tumorsAshworth, A. / Cold Spring Harbor Laboratory et al. | 2004
- 9
-
Genetics and biology of pancreatic ductal adenocarcinomaBardeesy, N. / Aguirre, A. J. / Bailey, G. / Lopez, L. / Hezel, A. F. / Redston, M. S. / Chin, L. / DePinho, R. A. / Cold Spring Harbor Laboratory et al. | 2004
- 10
-
Linking somatic genetic alterations and therapeuticsSellers, W. R. / Cold Spring Harbor Laboratory et al. | 2004
- 11
-
Genome-wide identification of DNA methylation using genome tiling arrayAburatani, H. / Hayashi, H. / Cold Spring Harbor Laboratory et al. | 2004
- 12
-
The RASSF1A isoform of RASSF1 promotes microtubule stability and suppresses tumorigenesisAdams, D. J. / van der Weyden, L. / Tachibana, K. K. / Gonzalez, M. A. / Ng, B. L. / Venkitaraman, A. R. / Arends, M. J. / Bradley, A. / Cold Spring Harbor Laboratory et al. | 2004
- 13
-
Identification of mitochondrial DNA mutations among and within epithelial ovarian tumorsAikhionbare, F. O. / Mehrabi, S. / Carey, D. / Partridge, E. / Cold Spring Harbor Laboratory et al. | 2004
- 14
-
The Mouse Tumor Biology database-Facilitating the selection of mouse models of human cancerAllio, T. C. / Krupke, D. M. / Vincent, M. J. / Sundberg, J. P. / Bult, C. J. / Eppig, J. T. / Cold Spring Harbor Laboratory et al. | 2004
- 15
-
MyrAkt1 requires S6K1 to induce insulinoma formationAlliouachene, S. / Lorenzo, L. / Lapointe, T. / Thomas, G. / Birnbaum, M. / Pende, M. / Cold Spring Harbor Laboratory et al. | 2004
- 16
-
E-cadherin interacts with TGF-beta receptor II in modulating cancer invasionAndl, C. D. / Bowser, M. / Fargnoli, B. / Okawa, T. / Takaoka, M. / Nakagawa, H. / Herlyn, M. / Rustgi, A. K. / Cold Spring Harbor Laboratory et al. | 2004
- 17
-
The BRCA1 gene-A possible mediator of the effect of the stress hormone hydrocortisone on breast cancer developmentAntonova, L. / Mueller, C. R. / Cold Spring Harbor Laboratory et al. | 2004
- 18
-
Telomere shortening leads to hemaotpoietic stem cell failure with anticipationArmanios, M. / Chang, C. / Brodsky, R. A. / Hawkins, A. / Chakravarti, A. / Hamosh, A. / Greider, C. W. / Cold Spring Harbor Laboratory et al. | 2004
- 19
-
A stabilized transcriptionally inactive p53-Mdm2 complex is DNA bound in Mdm2 SNP309 homozygous cellsArva, N. C. / Gopen, T. R. / Talbott, K. E. / Campbell, L. E. / Chicas, A. / White, D. E. / Bond, G. L. / Levine, A. J. / Bargonetti, J. / Cold Spring Harbor Laboratory et al. | 2004
- 20
-
Tropomyosin silencing alters TGF-beta control of invasion and metastasisBakin, A. / Varga, A. / Zheng, Q. / Safina, A. / Cold Spring Harbor Laboratory et al. | 2004
- 21
-
Unique mechanisms of p53 inactivation in malignant melanoma opens a way to a novel principle of treatmentBao, W. / Issaeva, N. / Enge, M. / Wiman, K. / Selivanova, G. / Stromblad, S. / Cold Spring Harbor Laboratory et al. | 2004
- 22
-
Kinome gene expression profiling as an approach to narrowing the search for mutated or activated kinases in human cancersBarbashina, V. / Shukla, N. / Saito, T. / Antonescu, C. R. / Chuai, S. / Olshen, A. B. / Ladanyi, M. / Cold Spring Harbor Laboratory et al. | 2004
- 23
-
Multiple mechanisms of cyclin D1 overexpression have differential effects on the cell cycle under hypoxiaBarnhart, B. C. / Gordan, J. D. / Simon, M. C. / Cold Spring Harbor Laboratory et al. | 2004
- 24
-
Inhibitor of apoptosis proteins (IAPs) and associated factors as prognostic indicators of pancreatic cancer cell resistance to oncotherapeuticsBastien, J. / Muradia, G. / Joly, M. A. / Liston, P. / LaCasse, E. / Korneluk, R. G. / Tsao, M. S. / Aubin, R. A. / Cold Spring Harbor Laboratory et al. | 2004
- 25
-
p38 regulates the induction of cyclooxygenase-2 in response to cellular stress in human mammary epithelial cellsBenton, G. M. / Gauthier, M. L. / Pickering, C. R. / Tlsty, T. D. / Cold Spring Harbor Laboratory et al. | 2004
- 26
-
Mutational profiling of cancer alleles in tumor-derived cell linesBenvenuti, S. / Bardelli, A. / Cold Spring Harbor Laboratory et al. | 2004
- 27
-
Targeted proteomic and structural analysis of 14-3-3sigma, a p53 effector commonly silenced in cancerBenzinger, A. / Muster, N. / Koch, H. / Popowicz, G. M. / Holak, T. A. / Yates, J. R. / Hermeking, H. / Cold Spring Harbor Laboratory et al. | 2004
- 28
-
Protein profiling technologies and their application to cancer researchBerberich, M. / Wu, T. / Stone, K. / Colangelo, C. / Williams, K. / Crawford, S. / Cold Spring Harbor Laboratory et al. | 2004
- 29
-
BRCA1 regulates the expression of cell cycle proteins via the ubiquitin-proteasome pathwayBerneman, D. / Talio, H. / Papa, M. Z. / Yarden, R. I. / Cold Spring Harbor Laboratory et al. | 2004
- 30
-
Suppression of p53 by Notch in lymphomagenesis-Implications for initiation and regressionBeverly, L. J. / Felsher, D. W. / Capobianco, A. J. / Cold Spring Harbor Laboratory et al. | 2004
- 31
-
Oncogenic Ras-mediated tumor suppressionBihani, T. / Jackson, T. J. / Lin, A. W. / Cold Spring Harbor Laboratory et al. | 2004
- 32
-
Selective inhibition of the p110delta isoform of PI3-kinase sensitizes primary acute leukemia to the chemotherapeutic drug etoposideBillottet, C. / Ruckle, T. / Rommel, C. / Vanhaesebroeck, B. / Khwaja, A. / Cold Spring Harbor Laboratory et al. | 2004
- 33
-
Regulation of p53 and MDM2 activity by MTBPBrady, M. / Vlaktovic, N. / Maguire, M. / Boyd, M. T. / Cold Spring Harbor Laboratory et al. | 2004
- 34
-
Tumor suppressing microRNAsBrown, D. / Ford, L. / Slack, F. J. / Cold Spring Harbor Laboratory et al. | 2004
- 35
-
The role of the Gab2 docking protein in growth factor signaling and breast cancerBrummer, T. / Schramek, D. / Gordon, S. L. / Bennett, H. / Daly, R. J. / Cold Spring Harbor Laboratory et al. | 2004
- 36
-
DNA damage response regulated Chk2-p53 pathway mediated apoptosis on longevity and tumorigenesis in Brca1 full-length deficiency miceCao, L. / Motoyama, N. / Deng, C. / Cold Spring Harbor Laboratory et al. | 2004
- 37
-
BCL-2 family members can be targeted by BH3 domain mimetics to kill cancer cellsCerto, M. / Nishino, M. / Sorcinelli, M. / Moore, V. / Korsmeyer, S. J. / Letai, A. / Cold Spring Harbor Laboratory et al. | 2004
- 38
-
Promoter methylation of Delta-TA isoform of p73 regulating the corresponding transcript expression level in gynecological cancersChan, K. Y. K. / Liu, S. S. / Leung, R. C. Y. / Cheung, A. N. Y. / Khoo, U. S. / Leung, T. W. / Ngan, H. Y. S. / Cold Spring Harbor Laboratory et al. | 2004
- 39
-
A novel role of Daxx in regulating TGF-beta signaling through SUMOylated Smad4Chang, C.-C. / Lin, D.-Y. / Fang, H.-I. / Chen, R.-H. / Shih, H.-M. / Cold Spring Harbor Laboratory et al. | 2004
- 40
-
Metabolic adaptation of brain metastasis from breast cancerChen, E. I. / Hewel, J. / Weber, M. / Yates, J. R. / Felding-Harbermann, B. / Cold Spring Harbor Laboratory et al. | 2004
- 41
-
T lymphocyte-mediated tumor immunosurveillance in a mouse model of lung adenocarcinomaCheung, A. F. / DuPage, M. J. P. / Dong, H. K. / Chen, J. / Jacks, T. / Cold Spring Harbor Laboratory et al. | 2004
- 42
-
Tissue specific knockout and knockon mutations of p27Kip1Chien, W.-M. / Garrison, K. / Fero, M. / Cold Spring Harbor Laboratory et al. | 2004
- 43
-
The role of polo-like kinase-2 in centriole duplicationCizmecioglu, O. / Perlewitz, A. / Hoffmann, I. / Cold Spring Harbor Laboratory et al. | 2004
- 44
-
The Sleeping Beauty transposon system-A tool for discovering genes involved in cancer in the mouseCollier, L. S. / Carlson, C. M. / Geurts, A. M. / Geurts, J. L. / Saplis, R. J. / Ravimohan, S. / Dupuy, A. J. / Largaespada, D. A. / Cold Spring Harbor Laboratory et al. | 2004
- 45
-
Identifying unique and redundant HIF-alpha function in tumorigenesisCovello, K. L. / Simon, M. C. / Keith, B. / Cold Spring Harbor Laboratory et al. | 2004
- 46
-
Aurora-A kinase overexpression cooperates with p53 heterozygosity in lymphomagenesisCowley, D. O. / Muse, G. W. / Van Dyke, T. / Cold Spring Harbor Laboratory et al. | 2004
- 47
-
Anti-tumor effects of the anti-inflammatory curcumin from spice tumeric on human solid tumors from primary and metastatic breast carcinoma and drug-resistant glioblastomaCrawford, S. / Greco, C. / Tuite, P. / Cold Spring Harbor Laboratory et al. | 2004
- 48
-
Regulation of hormone response pattern in mammary epithelial cells by gamma synucleinDackour, R. / Shi, Y. E. / Cold Spring Harbor Laboratory et al. | 2004
- 49
-
Heat shock transcription 1 (HSF1)-mediated heat shock response plays important roles in tumorigenesisDai, C. / Whitesell, L. / Steele, A. / Lindquist, S. / Cold Spring Harbor Laboratory et al. | 2004
- 50
-
Excess granulopeoisis and subsequent acute myeloid leukemia induced by complete loss of PU.1 in adult miceDakic, A. / Metcalf, D. / Di Rago, L. / Mifsud, S. / Wu, L. / Nutt, S. L. / Cold Spring Harbor Laboratory et al. | 2004
- 51
-
A new mouse to model BRAF-V600E initiated tumorigenesisDankort, D. / McMahon, M. / Cold Spring Harbor Laboratory et al. | 2004
- 52
-
Hypoxia induced resistance to chemotherapy is HIF-1alpha mediated and can be reversed by anti-VEGF antibody in neuroblastoma cell linesDas, B. / Tsuchida, R. / Yeger, H. / Malkin, D. / Baruchel, S. / Cold Spring Harbor Laboratory et al. | 2004
- 53
-
Estrogen receptor-alpha represses p53 function by direct interaction-A novel cellular mechanism with a clinical correlateDas, G. M. / Liu, W. / Konduri, S. D. / Nayak, B. K. / Bansal, S. / Rajasekaran, S. A. / Srivastava, P. / Sayeed, A. / Abraham, B. K. / Brauch, H. et al. | 2004
- 54
-
Genetic determinants of dysregulated neuroblast development in medulloblastomaDi Marcotullio, L. / Argenti, B. / Ferretti, E. / De Smaele, E. / Gallo, R. / Alesse, E. / Gulino, A. / Cold Spring Harbor Laboratory et al. | 2004
- 55
-
Reversible tumor suppression through regulated expression of synthetic microRNA precursorsDickins, R. / Hemann, M. / Zilfou, J. / Simpson, D. / Ibarra, I. / Hannon, G. / Lowe, S. / Cold Spring Harbor Laboratory et al. | 2004
- 56
-
Determinants of tumor cell fate and maintenance in mouse pancreatic cancer modelsDu, Y.-C. N. / Varmus, H. / Cold Spring Harbor Laboratory et al. | 2004
- 57
-
Inhibition of the IL-6-Stat3 pathway sensitizes resistant human ovarian cancer cells to paclitaxelDuan, Z. / Foster, R. / Mahoney, J. / Seiden, M. / Cold Spring Harbor Laboratory et al. | 2004
- 58
-
Integrin-mediated survival in primary prostate epithelial cells requires EGFR and c-MetEdick, M. J. / Knudsen, B. S. / Miranti, C. K. / Cold Spring Harbor Laboratory et al. | 2004
- 59
-
Role of p14ARF in regulating oligomerization and nucleolar localization of B23/NPMEnomoto, T. / Lindstrom, M. / Jin, A. / Zhang, Y. / Cold Spring Harbor Laboratory et al. | 2004
- 60
-
Molecular targets of HDAC inhibitors identified by genetic screeningEpping, M. T. / Wang, L. / Edel, M. J. / Hernandez, M. / Bernards, R. / Cold Spring Harbor Laboratory et al. | 2004
- 61
-
Angiomotin is required for vessel formation during in vitro differentiation of embryonic stem cellsErnkvist, M. / Aase, K. / Shimono, A. / Claesson-Welsh, L. / Holmgren, L. / Cold Spring Harbor Laboratory et al. | 2004
- 62
-
Myc-T58 phosphorylation by GSK3 is regulated by the APC-AXIN tumor suppressor complexFaga, G. / Amati, B. / Cold Spring Harbor Laboratory et al. | 2004
- 63
-
Selective killing of melanoma cells by exploiting differential effects of proteasome inhibition on Noxa and anti-apoptotic Bcl-2 proteinsFernandez, Y. / Verhaegen, M. / Wang, S. / Soengas, M. S. / Cold Spring Harbor Laboratory et al. | 2004
- 64
-
Redundant signals from cadherin-mediated and integrin-mediated adhesion regulate cyclin D1 expression in mammary epithelial cellsFournier, A. K. / Chung, B. M. / Assoian, R. K. / Cold Spring Harbor Laboratory et al. | 2004
- 65
-
Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancerFridman, J. / Liu, X. / Caulder, E. / Liu, C. / Hansbury, M. / Zhou, B.-B. / Yao, W. / Li, Y. / Vaddi, K. / Newton, R. et al. | 2004
- 66
-
Disruption of Mdm2 or Mdm4 in various cell types causes very distinct p53-mediated phenotypesFroment, P. / Francoz, S. / Maetens, M. / Bogaerts, S. / Doumont, G. / Marine, J.-C. / Cold Spring Harbor Laboratory et al. | 2004
- 67
-
Seladin-1 mutation associated with multiple human tumorsGalaktionov, K. / Maestro, R. / Chernova, O. / Barnett, G. H. / Hedge, M. / Demontis, S. / Miloslavskaya, I. / Cold Spring Harbor Laboratory et al. | 2004
- 68
-
Cooperativity of Akt and MAP kinase signaling in the development of androgen-independent prostate cancerGao, H. / Banach-Patrosky, W. A. / Ouyang, X. / Shen, M. M. / Abate-Shen, C. / Cold Spring Harbor Laboratory et al. | 2004
- 69
-
Dissecting the role of the neurotrophic receptor TrkB in anoikis resistance and metastasisGeiger, T. R. / Martinez-Munoz, C. / Douma, S. / Peeper, D. S. / Cold Spring Harbor Laboratory et al. | 2004
- 70
-
Correction of structure of tumor DNA by complex use of bacterial culture and antibiotic in vivoGharibyan, J. V. / Nersesyan, L. E. / Karapetyan, O. G. / Shahinyan, A. A. / Karapetyan, A. O. / Cold Spring Harbor Laboratory et al. | 2004
- 71
-
Single nucleotide polymorphisms in AKT1 modify DNA damage-induced apoptosisGil, G. A. / Harris, S. / Bond, E. / Bond, G. L. / Robins, H. L. / Levine, A. / Cold Spring Harbor Laboratory et al. | 2004
- 72
-
Elucidating CBX7 function in vivoGil, J. / Scott, C. L. / Hernando, E. / Cordon-Cardo, C. / Hemann, M. / Wendel, H. G. / Narita, M. / Beach, D. / Peters, G. / Lowe, S. W. et al. | 2004
- 73
-
Geminin predicts adverse clinical outcome in breast cancer by reflecting cell cycle progressionGonzalez, M. A. / Tachibana, K.-e. K. / Chin, S.-F. / Callagy, G. / Madine, M. A. / Vowler, S. L. / Pinder, S. E. / Laskey, R. A. / Coleman, N. / Cold Spring Harbor Laboratory et al. | 2004
- 74
-
REST/NRSF activates Bmi1 and regulates cerebellar progenitor self-renewal-Role in differentiation and cancerGopalakrishnan, V. / Su, X. / Stearns, D. / Pham, T. / Colman, H. / Solovyov, A. / Kagalwala, M. / Aldape, K. / Lang, F. F. / Fuller, G. et al. | 2004
- 75
-
Tumor suppressor activity of the Tip60 histone acetyltransferaseGorrini, C. / Squatrito, M. / Lough, J. / Amati, B. / Cold Spring Harbor Laboratory et al. | 2004
- 76
-
A proteomics-based approach to identify novel homeodomain-interacting protein kinase 2 (HIPK2) binding proteinsGradi, A. / Giorgi, A. / D Eliseo, D. / Schinina, M. E. / Sacchi, A. / Soddu, S. / Cold Spring Harbor Laboratory et al. | 2004
- 77
-
The cyclin dependent kinase inhibitor p21 is a crucial target for HDAC1 as a regulator of cellular proliferationGrausenburger, R. / Meunier, D. / Brunmeir, R. / Lagger, G. / Tischler, J. / Schuettengruber, B. / Weitzer, G. / Jenuwein, T. / Seiser, C. / Cold Spring Harbor Laboratory et al. | 2004
- 78
-
HIF-2alpha, hypoxic gene regulation, and tumor progressionGruber, M. / Keith, B. / Simon, M. C. / Cold Spring Harbor Laboratory et al. | 2004
- 79
-
A lentivirus-based RNA interference arrayed screen identifies regulators of mitosis and cell survival in human cellsGrueneberg, D. / Moffat, J. / Kim, S. Y. / Yang, X. / Hinkle, G. / Kloepfer, A. / Mizuno, H. / Hahn, W. / Hacohen, N. / Sabitini, D. et al. | 2004
- 80
-
Identification of apoptosis regulators with a gene trap approachGuardiola-Serrano, F. / Strolz, C. / von Melchner, H. / Altschmied, J. / Cold Spring Harbor Laboratory et al. | 2004
- 81
-
c-Myc modulates B cell development and transformation in a calcium-dependent, Tec kinase-independent mannerHabib, T. / Eisenman, R. N. / Tsang, M. / Nicks, A. / Wilson, L. / Rawlings, D. / de Alboran, I. / Knoepfler, P. / Iritani, B. M. / Cold Spring Harbor Laboratory et al. | 2004
- 82
-
A microRNA polycistron as a potential human oncogeneHe, L. / Thomson, J. M. / Hemann, M. / Hernando-Monge, E. / Mu, D. / Powers, S. / Cordon-Cardo, C. / Lowe, S. / Hammond, S. / Hannon, G. et al. | 2004
- 83
-
A comparison of murine and human mammary tumors using DNA microarrayHerschkowitz, J. I. / Simin, K. / Weigman, V. J. / Mikaelian, I. / Hu, Z. / Rasmussen, K. / Chandrasekharan, S. / Backlund, M. G. / Glazer, R. I. / Yin, Y. et al. | 2004
- 84
-
Characterization of the role of pVHL mutations in Chuvash polycythemiaHickey, M. M. / Rathmell, W. K. / Bezman, N. A. / Simon, M. C. / Cold Spring Harbor Laboratory et al. | 2004
- 85
-
Selective inactivation of p53 in prostate stroma in response to epithelial tumorigenesis; coevolution of both compartments leads to tumor progressionHill, R. / Song, Y. / Cardiff, R. D. / Van Dyke, T. / Cold Spring Harbor Laboratory et al. | 2004
- 86
-
Initiation of prostate cancer by complete Rb family inactivation causes selective pressure for compromised Pten functionHill, R. / Song, Y. / Cardiff, R. D. / Van Dyke, T. / Cold Spring Harbor Laboratory et al. | 2004
- 87
-
Visualizing the in vivo cell biology of metastasis in real timeHoffman, R. M. / Cold Spring Harbor Laboratory et al. | 2004
- 88
-
A novel approach to identifying genes involved in the stromal-tumor interfaceHolst, C. / Jung, K. / Varfolomeev, E. / Dowd, P. / Zhang, Z. / Wu, T. / Frantz, G. / French, D. / Ashkenazi, A. / Cold Spring Harbor Laboratory et al. | 2004
- 89
-
RAD001 (everolimus) improves the efficacy of replicating adenoviruses that target colon cancerHomicsko, K. / Lukashev, A. / Iggo, R. / Cold Spring Harbor Laboratory et al. | 2004
- 90
-
Single nucleotide polymorphisms in the p53 signal transduction pathway impact upon apoptosis and the age of onset of human cancersHarris, S. / Bond, G. L. / Hu, W. / Gil, G. / Robins, H. / Levine, A. J. / Cold Spring Harbor Laboratory et al. | 2004
- 91
-
Trp53^R^1^7^2^H and Kras^G^1^2^D cooperate to promote chromosomal instability in the absence of telomere erosion and define a unique genetic pathway to metastatic pancreatic ductal adenocarcinomaHingorani, S. R. / Wang, L. / Multani, A. S. / Combs, C. / Deramaudt, T. B. / Hruban, R. H. / Rustgi, A. K. / Chang, S. / Tuveson, D. A. / Cold Spring Harbor Laboratory et al. | 2004
- 92
-
Genomic analysis of breast cancer in families-The continuing challenge of genetic heterogeneityKing, M.-C. / Cold Spring Harbor Laboratory et al. | 2004
- 93
-
Large scale investigations of human cancer somatic geneticsFutreal, A. / Cold Spring Harbor Laboratory et al. | 2004
- 94
-
High resolution ROMA and FISH analysis of aneuploid and diploid breast tumorsHicks, J. / Grubor, V. / Esposito, D. / Navin, N. / Alexander, J. / Riggs, M. / Wigler, M. / Maner, S. / Zetterberg, A. / Cold Spring Harbor Laboratory et al. | 2004
- 95
-
Formation and function of cancer genomesChin, K. / Fridlyand, J. / Gray, J. W. / Guan, Y. / Jain, A. / Kuo, W.-L. / Lapuk, A. / Lockett, S. / McCormick, F. / Mills, G. et al. | 2004
- 96
-
Genetic alterations and therapy of human lung carcinomaMeyerson, M. / Cold Spring Harbor Laboratory et al. | 2004
- 97
-
How do cancer cells acquire the fuel needed to support cell growth?Lum, J. J. / Bauer, D. E. / Kong, M. / Harris, M. H. / Li, C. / Lindsten, T. / Thompson, C. B. / Cold Spring Harbor Laboratory et al. | 2004
- 98
-
Id proteins as essential regulators of tumor angiogenesisWallace, D. / Benezra, R. / de Candia, P. / Henke, E. / Ciarrocchi, A. / Ruzinova, M. / Solit, D. / Rosen, N. / Chao, S. / Zhao, Y. et al. | 2004
- 99
-
Tumor microenvironment control of cancer progression and metastasisKalluri, R. / Cold Spring Harbor Laboratory et al. | 2004
- 100
-
VEGF Trap-A potent anti-angiogenic agent with promise in cancer and other settingsYancopoulos, G. D. / Cold Spring Harbor Laboratory et al. | 2004
- 101
-
Understanding the role of the tumor microenvironment in neoplastic progression and metastasisEgeblad, M. / Welm, B. / Mehr, H.-K. / Krummel, M. F. / Werb, Z. / Cold Spring Harbor Laboratory et al. | 2004
- 102
-
The platelet angiogenesis proteome for early detection of cancerKlement, G. / Yip, T. / Italiano, J. / Folkman, J. / Cold Spring Harbor Laboratory et al. | 2004
- 103
-
BRCA1 directly modulates a gene expression required for estrogen biosynthesis-A possible mechanism of tissue-specific tumor suppressionHu, Y. / Aiyar, S. / Yue, W. / Ghosh, S. / Lu, Y. / Li, R. / Cold Spring Harbor Laboratory et al. | 2004
- 104
-
Maps of breast cancer LN and distant metastasesHu, Z. / He, X. / Karaca, G. / Fan, C. / Huang, C.-H. / Ewend, M. / Carey, L. / Perou, C. M. / Cold Spring Harbor Laboratory et al. | 2004
- 105
-
Menin associates with a trithorax family histone methyltransferase complex and with the Hoxc8 locusHughes, C. M. / Rozenblatt-Rosen, O. / Milne, T. A. / Copeland, T. D. / Levine, S. S. / Lee, J. C. / Hayes, D. N. / Shanmugam, K. S. / Bhattacharjee, A. / Biond, C. A. et al. | 2004
- 106
-
Oncogenic properties of the JSRV envelope proteinHull, S. / Maeda, N. / Hofacre, A. / Fan, H. / Cold Spring Harbor Laboratory et al. | 2004
- 107
-
S100 family members are differentially expressed during squamous cell carcinogenesisHummerich, L. / Mueller, R. / van der Sanden, M. / Kokocinski, F. / Tews, B. / Hahn, M. / Fuerstenberger, G. / Mauch, C. / Lichter, P. / Hess, J. et al. | 2004
- 108
-
Protein kinase CK2 phosphorylation of Cdc2-Looking for a roleIacomino, G. / Medici, M. C. / Napoli, D. / Russo, M. / van den Bos, C. / Marshak, D. R. / Russo, G. L. / Cold Spring Harbor Laboratory et al. | 2004
- 109
-
Acetylation and regulation of the Rb/E2F1 complex in response to DNA damageIanari, A. / Pediconi, N. T. / Levrero, M. / Gulino, A. / Cold Spring Harbor Laboratory et al. | 2004
- 110
-
Perp is a p63-regulated gene essential for epithelial integrityIhrie, R. A. / Marques, M. R. / Nguyen, B. T. / Horner, J. S. / Papazoglu, C. / Bronson, R. T. / Mills, A. A. / Attardi, L. D. / Cold Spring Harbor Laboratory et al. | 2004
- 111
-
A tumor suppressor RUNX3 negatively regulates Wnt signaling-Complementary regulation of intestinal epithelium by Wnt and TGF-betaIto, K. / Lim, A. / Goh, M. / Voon, D. / Ito, Y. / Cold Spring Harbor Laboratory et al. | 2004
- 112
-
A FRET-based probe for epidermal growth factor receptor bound non-covalently to a pair of synthetic amphipathic helixesItoh, R. E. / Kurokawa, K. / Fujioka, A. / Sharma, A. / Mayer, B. J. / Matsuda, M. / Cold Spring Harbor Laboratory et al. | 2004
- 113
-
The role of mutant p53 stability in the dominant-negative of gain-of-function phenotypes in miceIwakuma, T. / Terzian, T. / Lang, G. A. / Neumann, M. / Lozano, G. / Cold Spring Harbor Laboratory et al. | 2004
- 114
-
Identification of mechanisms of breast cancer metastasis using tissue specific virus deliveryJechlinger, M. / Varmus, H. E. / Cold Spring Harbor Laboratory et al. | 2004
- 115
-
Skp2 regulates cell proliferation by networking with Rb, cyclin A and p27Ji, P. / Zhu, L. / Cold Spring Harbor Laboratory et al. | 2004
- 116
-
Dissecting p53 function using transactivation mutant knock-in miceJohnson, T. M. / Meade, K. / Marques, M. / Attardi, L. D. / Cold Spring Harbor Laboratory et al. | 2004
- 117
-
BRCA1/BARD1-mediated association of RCC1 with chromatin is required for the fidelity of mitosis and mitotic exitJoukov, V. / Prokhorova, T. / Gerson, R. / White, E. / Walter, J. C. / Livingston, D. M. / Cold Spring Harbor Laboratory et al. | 2004
- 118
-
Activity and function of the p38 MAPK pathway in cancer cell survival and invasionJunttila, M. R. / Ala-aho, R. / Puustinen, P. / Jokilehto, T. / Peltonen, J. / Grenman, R. / Jaakkola, P. / Kahari, V.-M. / Westermarck, J. / Cold Spring Harbor Laboratory et al. | 2004
- 119
-
Resistance to Mek/Erk-mediated Fra-1 accumulationKakumoto, K. / Sukezane, T. / Oneyama, C. / Hanafusa, H. / Akagi, T. / Cold Spring Harbor Laboratory et al. | 2004
- 120
-
Phosphoinositide 3-kinase point mutations prevalent in human cancer are tumorigenicKang, S. / Bader, A. G. / Zhao, L. / Vogt, P. K. / Cold Spring Harbor Laboratory et al. | 2004
- 121
-
Regulation of stromal thrombospondin-1 in metastatic cancer growthKang, S.-Y. / Liu, N. / Lee, J. / Shieh, A. / Watnick, R. S. / Cold Spring Harbor Laboratory et al. | 2004
- 122
-
Modeling melanoma in mice by expression of endogenous oncogenic BRAF allelesKarreth, F. / Jacobetz, M. / Tuveson, D. A. / Cold Spring Harbor Laboratory et al. | 2004
- 123
-
Targeting TACE-dependent growth factor shedding in breast cancerKenny, P. A. / Bissell, M. J. / Cold Spring Harbor Laboratory et al. | 2004
- 124
-
Genomic and proteomic analysis of mutations in EGFRKitchel, R. / Hwang, S. / Han, D. / Furneaux, H. / Cold Spring Harbor Laboratory et al. | 2004
- 125
-
Defective DNA damage checkpoint pathways in primary prostatic epithelial cellsKiviharju, T. / Peehl, D. M. / Laiho, M. / Cold Spring Harbor Laboratory et al. | 2004
- 126
-
Spatial and functional heterogeneity of sphingolipid-rich membrane domainsKiyokawa, E. / Baba, T. / Kobayashi, T. / Cold Spring Harbor Laboratory et al. | 2004
- 127
-
STAT3 regulates telomerase expression in human cancer and primary cellsKonnikova, L. / Simeone, M. / Kruger, M. / Kotecki, M. / Cochran, B. H. / Cold Spring Harbor Laboratory et al. | 2004
- 128
-
Array-based functional knock-down screen for genes involved in RAS^V^1^2-induced senescenceKuilman, T. / Peeper, D. S. / Cold Spring Harbor Laboratory et al. | 2004
- 129
-
NPM and PML interact in DNA damaged cellsKurki, S. / Laiho, M. / Cold Spring Harbor Laboratory et al. | 2004
- 130
-
Control of cell proliferation and apoptosis by Mob as tumor suppressor, MatsLai, Z.-C. / Wei, X. / Shimizu, T. / Ho, L.-L. / Cold Spring Harbor Laboratory et al. | 2004
- 131
-
Investigating the role of EGFR mutations in NSCLCLane, K. / Jacks, T. / Cold Spring Harbor Laboratory et al. | 2004
- 132
-
Deregulated growth control by inactivation of the Suv39h1 histone methyltransferase accelerates Myc-driven lymphomagenesis and impairs drug-inducible senescenceLee, S. / Gontarewicz, A. / Loddenkemper, C. / Peters, A. H. F. M. / Mirossay, A. / Stein, H. / Dorken, B. / Jenuwein, T. / Schmitt, C. A. / Cold Spring Harbor Laboratory et al. | 2004
- 133
-
Trip-Br1-A novel transcriptional regulator of the tumor suppressor ARF (alternative reading frame)Lehmkuhl, K. V. / Kim, S.-W. / Yuan, L. / Holzschu, D. / Cold Spring Harbor Laboratory et al. | 2004
- 134
-
The mitotic functions of the Bloom syndrome protein BLMLeng, M. / Chan, D. / Luo, H. / Zhu, C. / Qin, J. / Wang, Y. / Cold Spring Harbor Laboratory et al. | 2004
- 135
-
Snail is an early effector of Gli1-induced transformation in epithelial cellsLi, X. / Deng, W. / Nail, C. D. / Bailey, S. K. / Ruppert, J. M. / Lobo-Ruppert, S. M. / Cold Spring Harbor Laboratory et al. | 2004
- 136
-
Defining the apoptotic pathways underlying histone deacetylase inhibitor-mediated tumor therapyLindemann, R. K. / Newbold, A. / Whitecross, K. / Dear, A. E. / Scott, C. / Wei, A. / Lowe, S. W. / Johnstone, R. W. / Cold Spring Harbor Laboratory et al. | 2004
- 137
-
Chemotherapy resistance mediated by the Rb tumor suppressor geneLiu, H. / Macleod, K. F. / Cold Spring Harbor Laboratory et al. | 2004
- 138
-
Molecular characterization of photosensitizer-photodynamic therapy (PDT) by gene expression profilingLiu, K.-H. / Chung, Y.-W. / Chang, M.-F. / Lin, J.-H. / Lou, P.-J. / Wang, C.-P. / Cold Spring Harbor Laboratory et al. | 2004
- 139
-
Genetic analysis on a collection of colorectal cancer cell linesLiu, Y. / Bicknell, D. / Hollins, L. / Wilson, C. / Miller, C. / Bodmer, W. / Cold Spring Harbor Laboratory et al. | 2004
- 140
-
Maturation-independence of KLF4, a potential tumor initiator, in human cutaneous squamous cell carcinomaLiu, Z. / Huang, C. C. / Bailey, S. K. / Frost, A. R. / Nail, C. D. / Ruppert, J. M. / Lobo-Ruppert, S. M. / Cold Spring Harbor Laboratory et al. | 2004
- 141
-
Molecular mechanisms underlying aggressive conversion of dormant metastasisLu, X. / Yan, J. / Chen, Y. / Massague, J. / Kang, Y. / Cold Spring Harbor Laboratory et al. | 2004
- 142
-
NSAIDs and salicylate derivatives affect cell cycle progression in colorectal cancer cells by activating cellular checkpoint mechanismsLuciani, M. G. / Campregher, C. / Gasche, C. / Cold Spring Harbor Laboratory et al. | 2004
- 143
-
Proteomic identification of biomarkers for profiling HBV+ hepatocellular carcinoma in early tumor stageLuk, J. / Peng, J. R. / Leng, X. S. / Fan, S.-T. / Cold Spring Harbor Laboratory et al. | 2004
- 144
-
Characterization of BRCA1 promoter regulatory elementsMacDonald, G. / Mueller, C. R. / Cold Spring Harbor Laboratory et al. | 2004
- 145
-
Genomic profiling of mouse thymic lymphomas using whole genome BAC arraysMao, J.-H. / Li, J. / Jiang, T. / Li, Q. / Wu, D. / Perez-Losada, J. / DelRosario, R. / Peterson, L. / Balmain, A. / Cai, W.-W. et al. | 2004
- 146
-
BCL6 is regulated by p53 through a response element frequently disrupted in B cell non-Hodgkin's lymphomaMargalit, O. / Granot, G. / Amariglio, N. / Minsky, N. / Shaklai, S. / Shimoni, A. / Harmelin, A. / Givol, D. / Shohat, M. / Oren, M. et al. | 2004
- 147
-
Defining the therapeutic potential of Trp53 restoration in Myc-driven lymphomasMartins, C. P. / Evan, G. / Cold Spring Harbor Laboratory et al. | 2004
- 148
-
IFI16 is a novel WT1 target gene identified by expression profiling in syndromic versus sporadic Wilms' tumorsMason, J. M. / Kim, M. / Li, C.-M. / Berkofsky-Fessler, W. / Choubey, D. / Grundy, P. E. / Tycko, B. / Licht, J. D. / Cold Spring Harbor Laboratory et al. | 2004
- 149
-
Proteomic analysis of early stages in carcinogenesisMcLean, A. / Wilson, J. B. / Cold Spring Harbor Laboratory et al. | 2004
- 150
-
Analysis of gene expression profiles in acute myeloid leukemiaMeani, N. / Alcalay, M. / Cold Spring Harbor Laboratory et al. | 2004
- 151
-
A genomic signature for the invasive growth programMedico, E. / D Alessandro, L. / Gentile, A. / Montemurro, F. / Church, G. / Comoglio, P. M. / Cold Spring Harbor Laboratory et al. | 2004
- 152
-
Large-scale amplification and gene conversion events initiated by broken chromosome ends in p53-deficient mammalian cultured cellsMesner, L. D. / Li, X. / Shan, Y. / Hamlin, J. L. / Cold Spring Harbor Laboratory et al. | 2004
- 153
-
Establishment of molecular characterized human tumor xenograft mouse models for development and evaluation of new tumor therapiesMischek, D. / Rosenfellner, D. / Zwickl, H. / Staettner, S. / Metzl, C. / Zatloukal, K. / Gunzburg, W. H. / Hohenadl, C. / Cold Spring Harbor Laboratory et al. | 2004
- 154
-
An insulator strategy in prevention of retrovirus mediated tumorigenesisMitra, K. / Lenz, J. / Cold Spring Harbor Laboratory et al. | 2004
- 155
-
Role of bone marrow-derived precursor cells in tumor angiogenesisMittal, V. / Nolan, D. J. / Mellick, A. S. / Gupta, S. / Xue, W. / Cold Spring Harbor Laboratory et al. | 2004
- 156
-
Structural and signaling requirements for Shp2 mutant-evoked leukemogenesisMohi, M. G. / Williams, I. / Chan, G. / Cohen, S. / Boulton, C. / Araki, T. / Kutok, J. L. / Gilliland, D. G. / Neel, B. G. / Cold Spring Harbor Laboratory et al. | 2004
- 157
-
beta-interferon triggers a checkpoint pathway, p53 modifications and premature cellular senescenceMoiseeva, O. / Mallette, F. A. / Mukhopadhyay, U. K. / Ferbeyre, G. / Cold Spring Harbor Laboratory et al. | 2004
- 158
-
Non-Cdk-bound p27 is a marker for TGF-beta induced growth arrestMonkkonen, M. / Tiihonen, E. / Band, A. / Laiho, M. / Cold Spring Harbor Laboratory et al. | 2004
- 159
-
Utilization of gene expression profiles to bridge in vitro and in vivo oncogenic phenotypesMori, S. / Bild, A. / Chang, J. / Yao, G. / Nevins, J. / Cold Spring Harbor Laboratory et al. | 2004
- 160
-
WT1 regulates ERK1/2 activity through dual mechanismsMorrison, D. J. / Kim, M. / Mason, J. M. / Berkofsky-Fessler, W. / Li, C.-M. / Tycko, B. / Licht, J. D. / Cold Spring Harbor Laboratory et al. | 2004
- 161
-
Structural mechanism of the bromodomain of the co-activator CBP in p53 transcriptional activationMujtaba, S. / He, Y. / Zeng, L. / Yan, S. / Plotnikova, O. / Sachchidanand, O. / Zeleznik-Le, N. J. / Zhou, M. M. / Cold Spring Harbor Laboratory et al. | 2004
- 162
-
A novel conditional and reversibly switchable transgenic mouse to probe the biological consequences of acute and chronic Myc deregulation in vivoMurphy, D. J. / Kogan, S. C. / Evan, G. I. / Cold Spring Harbor Laboratory et al. | 2004
- 163
-
Deterministic shuttling of a DNA motor proteinMyong, S. / Rasnik, I. / Joo, C. / Lohman, T. M. / Ha, T. / Cold Spring Harbor Laboratory et al. | 2004
- 164
-
Apoptosis induced by TGF-beta in human hepatocellular carcinoma (HCC) is mediated by Cdc2 activation with Wee1 downregulation and inhibited by p21^C^i^p^1 induction simultaneously occurredNagahara, H. / Kogiso, T. / Shiratori, K. / Cold Spring Harbor Laboratory et al. | 2004
- 165
-
Role of the C-terminus of Mec1 checkpoint kinase in its localization to sites of DNA damageNakada, D. / Hirano, Y. / Sugimoto, K. / Cold Spring Harbor Laboratory et al. | 2004
- 166
-
Inhibition of histone acetylation by transcription factor JDP2 is critical during differentiation of F9 cellsNakade, K. / Pan, J. / Liu, B. / Yamasaki, T. / Kimura, M. / Murata, T. / Yokoyama, K. K. / Cold Spring Harbor Laboratory et al. | 2004
- 167
-
Serine/threonine protein phosphatase 5 colocalizes with alpha- and gamma-tubulins at centromeres and is involved in microtubule organizationNakagama, H. / Tsuchiya, N. / Nakashima, K. / Fukuda, H. / Sugimura, T. / Hara-Fujita, K. / Cold Spring Harbor Laboratory et al. | 2004
- 168
-
A cancer-specific transcriptional signature present at high frequency in human neoplasiaNicassio, F. / Bianchi, F. / Capra, M. / Vecchi, M. / Confalonieri, S. / Bianchi, M. / Pajalunga, D. / Crescenzi, M. / Bonapace, I. M. / Di Fiore, P. P. et al. | 2004
- 169
-
Regulation of apoptotic Mst1 kinase activity by RASSF1A in vivoOh, H. J. / Lee, K.-K. / Song, S. J. / Song, M. S. / Lee, J. H. / Qin, J. / Yonehara, S. / Lim, D.-S. / Cold Spring Harbor Laboratory et al. | 2004
- 170
-
Skin papillomas regress if C/EBP DNA binding is abolishedOh, W.-J. / Gerdes, M. / Yuspa, S. / Vinson, C. / Cold Spring Harbor Laboratory et al. | 2004
- 171
-
Differential effects of mutant p53 alleles on the development of advanced murine lung cancerOlive, K. P. / Jackson, E. L. / Tuveson, D. A. / Bronson, R. / Crowley, D. / Brown, M. / Jacks, T. / Cold Spring Harbor Laboratory et al. | 2004
- 172
-
Sp1 is phosphorylated in response to DNA damage through the ATM pathwayOlofsson, B. A. / Azizkhan-Clifford, J. / Cold Spring Harbor Laboratory et al. | 2004
- 173
-
Activated Ras prevents anoikis mainly through a MEK/ERK pathway in fibroblastsOneyama, C. / Sukezane, T. / Kakumoto, K. / Hanafusa, H. / Akagi, T. / Cold Spring Harbor Laboratory et al. | 2004
- 174
-
Novel E2F2B isoform functions as tumor suppressor in Myc-induced T-cell lymphomagenesisOpavsky, R. / Tsai, S. / Sharma, N. / Guimond, M. / Aurora, A. / Opavska, J. / Trikha, P. / Stephens, J. A. / Fernandez, S. A. / Muthusamy, N. et al. | 2004
- 175
-
Breast cancer genomics reveals highly complex rearrangement patterns and opens the question of what events are essentialOrsetti, B. / Gelsi-Boyer, V. / Cervera, N. / Lasorsa, L. / Nugoli, M. / Rouge, C. / Chuchana, P. / Bertucci, F. / Rodriguez, C. / Chaffanet, M. et al. | 2004
- 176
-
p53 induction and activity are inhibited by discrete viral proteins in adenovirus infected cellsO Shea, C. / Soria, C. / Choi, S. / Johnson, L. / McCormick, F. / Cold Spring Harbor Laboratory et al. | 2004
- 177
-
An unbiased shRNA screen identifies critical target genes of Myc and potential targets for therapy in human tumor cellsOtto, T. / Horn, S. / Berwanger, B. / Eilers, M. / Cold Spring Harbor Laboratory et al. | 2004
- 178
-
Molecular network aberrations define subtypes of non small cell lung cancerPapageorgis, P. / Pan, H. / Russo, A. L. / Thiagalingam, S. / Cold Spring Harbor Laboratory et al. | 2004
- 179
-
Elucidating the mechanisms of anti-estrogen resistance in breast cancerPark, J. / Gonzalez-Malerva, L. / Hines, L. / Hu, Y. / LaBaer, J. / Cold Spring Harbor Laboratory et al. | 2004
- 180
-
Using p16^I^N^K^4^a-deficient human fibroblasts to study the minimum requirements for transformationPeters, G. / Jones, R. / Sanij, E. / Rodriguez-Niedenfuhr, M. / Brookes, S. / Rowe, J. / Drayton, S. / Rodway, H. / Cold Spring Harbor Laboratory et al. | 2004
- 181
-
Investigation of the role of insulin-like growth factor 1-receptor in the poorly differentiated lung carcinoma cell line DLKP and its invasive/chemotherapeutic drug resistant variantsPierce, A. / Gammell, P. / Barron, N. / Clynes, M. / Cold Spring Harbor Laboratory et al. | 2004
- 182
-
The tumor suppressor gene HIC1 (Hypermethylated in Cancer 1) is a sequence-specific transcriptional repressorPinte, S. / Rood, B. / Stankovic-Valentin, N. / Deltour, S. / Monte, D. / Guerardel, C. / Leprince, D. / Cold Spring Harbor Laboratory et al. | 2004
- 183
-
Protection of human telomeresCelli, G. B. / Hockemeyer, D. / de Lange, T. / Cold Spring Harbor Laboratory et al. | 2004
- 184
-
Telomeres and telomerase in cancer and stem cell failureGreider, C. W. / Feldser, D. / Hao, L. / Strong, M. / Armanios, M. / Cold Spring Harbor Laboratory et al. | 2004
- 185
-
Regulation of telomerase by human papillomavirusesGalloway, D. / Gewin, L. / Luo, W. / Grandori, C. / Myers, H. / Kiyono, T. / Klingelhutz, A. / McDougall, J. / Cold Spring Harbor Laboratory et al. | 2004
- 186
-
Tumor suppression, aging and cellular senescenceCampisi, J. / Cold Spring Harbor Laboratory et al. | 2004
- 187
-
The Arf tumor suppressorZindy, F. / Kuo, M.-L. / den Besten, W. / Bertwistle, D. / Sugimoto, M. / Tago, K. / Roussel, M. F. / Sherr, C. J. / Cold Spring Harbor Laboratory et al. | 2004
- 188
-
Identification of senescent cells in pre-malignant tumorsSerrano, M. / Cold Spring Harbor Laboratory et al. | 2004
- 189
-
Mouse models for human liver tumorsTward, A. D. / Goga, A. / Jones, K. / Felsher, D. / Wang, R. / Bishop, J. M. / Cold Spring Harbor Laboratory et al. | 2004
- 190
-
A mouse model for small cell lung cancerBerns, A. / Angrill, J. C. / van Montfort, E. / Zevenhoven, J. / Jonkers, J. / Meuwissen, R. / Cold Spring Harbor Laboratory et al. | 2004
- 191
-
A new generation of animal tumor models for target validation in cancerBarbacid, M. / Cold Spring Harbor Laboratory et al. | 2004
- 192
-
Modeling cancer in the mouseJacks, T. / Cold Spring Harbor Laboratory et al. | 2004
- 193
-
Regulation of apoptosis and senescence by cancer genesLowe, S. W. / Cold Spring Harbor Laboratory et al. | 2004
- 194
-
Determining the requirements for tumor maintenance in vivoEvan, G. I. / Christophorou, M. / Hunt, A. / Swigart, L. B. / Lawlor, B. / Soucek, L. / Murphy, D. / Cold Spring Harbor Laboratory et al. | 2004
- 195
-
Modeling cancer-specific chromosomal translocations using conditional allelesForster, A. / Drynan, L. / Pannell, R. / Codrington, R. / Metzler, M. / Daser, A. / Rabbitts, T. / Cold Spring Harbor Laboratory et al. | 2004
- 196
-
Mechanisms of cancer invasiveness and metastasisWeinberg, R. A. / Cold Spring Harbor Laboratory et al. | 2004
- 197
-
Widespread regulation of chromatin structure by the Myc oncoproteinKnoepfler, P. S. / Cheng, P. F. / Gafken, P. R. / Eisenman, R. N. / Cold Spring Harbor Laboratory et al. | 2004
- 198
-
Control of proliferation and apoptosis by the E2F transcription factorsLees, J. / Cold Spring Harbor Laboratory et al. | 2004
- 199
-
Early epigenetic and genetic events in cancerTlsty, T. D. / Crawford, Y. / Gauthier, M. L. / McDermott, K. / Miller, C. / Reynolds, P. / Zhang, J. / Pickering, C. / Cold Spring Harbor Laboratory et al. | 2004
- 200
-
Epigenetic changes in cancer and pre-neoplasia-Many gene and many pathways involved in transformationHerman, J. G. / Cold Spring Harbor Laboratory et al. | 2004
- 201
-
The epigenetics of cancer etiologyFeinberg, A. P. / DeBaun, M. / Sakatani, T. / Kaneda, A. / Iacobuzio-Donahue, C. / Cold Spring Harbor Laboratory et al. | 2004
- 202
-
Linking activating mutations in the Epidermal Growth Factor Receptor to responsiveness of non-small cell lung cancer to the tyrosine kinase inhibitorsHaber, D. / Bell, D. / Sordella, R. / Lynch, T. / Settleman, J. / Cold Spring Harbor Laboratory et al. | 2004
- 203
-
The role of aberrant gene silencing in tumor progression-Implications for control of cancerBaylin, S. B. / Cold Spring Harbor Laboratory et al. | 2004
- 204
-
Argonaughty-The secret life of slicerHannon, G. / Cold Spring Harbor Laboratory et al. | 2004
- 205
-
A genetic screen for candidate tumor suppressorsWestbrook, T. F. / Martin, E. S. / Schlabach, M. R. / Leng, Y. / Liang, A. C. / Feng, B. / Zhao, J. J. / Roberts, T. / Mandel, G. / Hannon, G. et al. | 2004
- 206
-
Integrating expression profiling into oncology drug discoveryFriend, S. / Cold Spring Harbor Laboratory et al. | 2004
- 207
-
Uncovering the molecular pathways that cause resistance to targeted cancer therapeutics through functional geneticsBernards, R. / Cold Spring Harbor Laboratory et al. | 2004
- 208
-
Using high throughput functional screens to identify potential chemotherapeutic targetsLaBaer, J. / Brizuela, L. / Harlow, E. / Cold Spring Harbor Laboratory et al. | 2004
- 209
-
Multiple mutations in tumor maintenance in mouse models of breast cancerPodsypanina, K. / Varmus, H. / Cold Spring Harbor Laboratory et al. | 2004
- 210
-
A role for E2F6 in the restriction of male germ cell specific gene expressionPohlers, M. / Truss, M. / Frede, U. / Strehle, M. / Kuban, R.-J. / Hoffmann, B. / Morkel, M. / Birchmeier, C. / Hagemeier, C. / Cold Spring Harbor Laboratory et al. | 2004
- 211
-
Lung tumorigenesis in mice expressing a point mutation in the EGFR gene found in NSCLC patientsPoliti, K. / Pao, W. / Zakowski, M. F. / Varmus, H. / Cold Spring Harbor Laboratory et al. | 2004
- 212
-
Direct regulation of ribosomal gene transcription by c-Myc during granulocyte differentiationPoortinga, G. / Wall, M. / Hannan, R. / McArthur, G. / Cold Spring Harbor Laboratory et al. | 2004
- 213
-
The role of INK4 inhibitors in the regulation of CDK4/6 in murine modelsRamsey, M. R. / Krishnamurthy, J. / Torrice, C. / Ligon, K. L. / Xiong, Y. / Sharpless, N. E. / Cold Spring Harbor Laboratory et al. | 2004
- 214
-
Identification and characterization of tumor-associated humoral antigensRauch, J. / Ahlemann, M. / Schaffrik, M. / Mack, B. / Lang, S. / Zeidler, R. / Gires, O. / Cold Spring Harbor Laboratory et al. | 2004
- 215
-
Regulation of the BRCA1 promoter by 53BP1Rauch, T. / Zhong, X. / Pfeifer, G. / Xu, X. / Cold Spring Harbor Laboratory et al. | 2004
- 216
-
Dual specificity phosphatase 1 and serum/glucocorticoid regulated kinase are downregulated in prostate cancerRauhala, H. E. / Porkka, K. P. / Tolonen, T. T. / Martikainen, P. M. / Tammela, T. L. J. / Visakorpi, T. / Cold Spring Harbor Laboratory et al. | 2004
- 217
-
Awakening RARB2 tumor suppressor activity in breast cancer cellsRen, M. / Pozzi, S. / Rossetti, S. / Bistulfi, G. / Somenzi, G. / Sacchi, N. / Cold Spring Harbor Laboratory et al. | 2004
- 218
-
An oncogenic RNA?Repellin, C. E. / Wilson, J. B. / Cold Spring Harbor Laboratory et al. | 2004
- 219
-
Profiling tyrosine phosphorylation in non small cell lung cancerRikova, K. / Guo, A. / Zeng, Q. / Lee, K. / Rush, J. / Polakiewicz, R. / Comb, M. J. / Cold Spring Harbor Laboratory et al. | 2004
- 220
-
Atypical protein kinase C function is required for migration and invasion by v-Src transformed fibroblastsRodriguez, E. M. / Martin, G. / Cold Spring Harbor Laboratory et al. | 2004
- 221
-
Inhibition of apoptosis by Mad1 is mediated by repression of the PTEN tumor suppressor geneRottman, S. / Speckgens, S. / Luscher-Firzlaff, J. / Luscher, B. / Cold Spring Harbor Laboratory et al. | 2004
- 222
-
A DR5-dependent synthetic lethal relationship between Myc overexpression and GSK3beta/FBW7 loss of functionRottmann, S. / Wang, Y. / Nasoff, M. / Deveraux, Q. L. / Quon, K. C. / Cold Spring Harbor Laboratory et al. | 2004
- 223
-
The parafibromin tumor suppressor protein is part of a human Paf1 complexRozenblatt-Rosen, O. / Hughes, C. M. / Nannepaga, S. J. / Shanmugam, K. S. / Copeland, T. D. / Guszczynski, T. / Resau, J. H. / Meyerson, M. / Cold Spring Harbor Laboratory et al. | 2004
- 224
-
p53 codon 72 polymorphism-Implications on tumor development and response to anti-cancer drugsSabapathy, K. / Siddique, M. M. / Vikhanskaya, F. / Balram, C. / Fiszer-Maliszewska, L. / Tan, P. / Soo, K. C. / Cold Spring Harbor Laboratory et al. | 2004
- 225
-
Differentially expressed genes defined by expression profiling of human cancers with chimeric transcription factors provide an enriched source of candidate transcriptional targets with potential as therapeutic targetsSaito, T. / Nagai, M. / Tsuda, M. / Lae, M. / Olshen, A. B. / Chuai, S. / Gall, S. / Barr, F. G. / Haber, D. A. / Gerald, W. L. et al. | 2004
- 226
-
A screen for MII-AF9 cooperating mutations in leukemogenesis using MLV-based mutagenesisSaplis, R. / Hudson, W. / Kersey, J. / Largaespada, D. / Cold Spring Harbor Laboratory et al. | 2004
- 227
-
Microarray analysis of gene copy number and gene expression in prostate cancerSaramaki, O. / Porkka, K. / Vessella, R. / Visakorpi, T. / Cold Spring Harbor Laboratory et al. | 2004
- 228
-
The cancer-associated E3-ubiquitin ligase EDD is a novel regulator of cell-cell adhesionSaunders, D. N. / Clancy, J. / Morton, R. / Sutherland, R. L. / Henderson, M. / Watts, C. K. / Cold Spring Harbor Laboratory et al. | 2004
- 229
-
Post-transcriptional regulation of BRCA1 via the 3'UTR-Identification of novel cis and trans regulatorsSaunus, J. M. / Wardrop, S. L. / French, J. D. / Beveridge, D. J. / Hatchell, E. C. / Dinnis, D. M. / Gason, A. A. / Simpson, K. J. / Leedman, P. J. / Brown, M. A. et al. | 2004
- 230
-
Characterization of a conditional mutation in the mouse Bub1 geneSchliekelman, M. / Cowley, D. / Van Dyke, T. / Cold Spring Harbor Laboratory et al. | 2004
- 231
-
IKKalpha regulates G1 phase progression of pancreatic cancer cells by the transcriptional regulation of the F-box protein skp2Schneider, G. / Saur, D. / Siveke, J. / Fritsch, R. / Schmid, R. M. / Cold Spring Harbor Laboratory et al. | 2004
- 232
-
H. pylori induces precancerous changes in the gastric mucosa of patients at inner-city hospitals in New YorkSchneller, J. / Straus, G. W. / Villanueva, R. / Gupta, R. / Mustafa, Y. / Raffaniello, R. D. / Cold Spring Harbor Laboratory et al. | 2004
- 233
-
Understanding drug-resistance in a mouse model of lymphoma-A microarray approachScott, C. L. / Jiang, C. / Das, D. / Hernando, E. / Narita, M. / Hemann, M. / Wendel, H. G. / Cordon-Cardo, C. / Zhang, M. / Sachidanandam, R. et al. | 2004
- 234
-
C/EBPbeta cooperates with RB:E2F to mediate Ras-induced cellular senescenceSebastian, T. / Thomas, S. / Sage, J. / Johnson, P. F. / Cold Spring Harbor Laboratory et al. | 2004
- 235
-
Identification of downstream targets of estrogen and c-Myc induced mitogenesis in breast cancer cellsSergio, C. M. / Butt, A. J. / Caldon, C. E. / McNeil, C. M. / Musgrove, E. A. / Sutherland, R. L. / Cold Spring Harbor Laboratory et al. | 2004
- 236
-
Tumor dormancy uncovered upon Myc inactivation in hepatocellular cancerShachaf, C. M. / Bendapudi, P. K. / Bradon, N. / Yang, Q. / Borowsky, A. D. / Ruebner, B. / Felsher, D. W. / Cold Spring Harbor Laboratory et al. | 2004
- 237
-
Directing aptamers to multiple discrete sites on a regulator of cellular transformationShi, H. / Fan, X. / Lis, J. T. / Cold Spring Harbor Laboratory et al. | 2004
- 238
-
Regulation of Pdgf receptor beta in vascular mural cells by the Arf tumor suppressor geneSilva, R. / Thornton, J. D. / Martin, A. C. / Skapek, S. X. / Cold Spring Harbor Laboratory et al. | 2004
- 239
-
Controlling brain tumor growth inhibiting cytoplasmic c-Fos driven phospholipid synthesis activationSilvestre, D. C. / Gil, G. A. / Portal, M. M. / Caputto, B. L. / Cold Spring Harbor Laboratory et al. | 2004
- 240
-
A comparison of murine and human mammary tumors using DNA microarraysSimin, K. / Herschkowitz, J. I. / Weigman, V. J. / Mikaelian, I. / Hu, Z. / Rasmussen, K. / Chandrasekharan, S. / Backlund, M. G. / Glazer, R. I. / Yin, Y. et al. | 2004
- 241
-
Clinically observed BCR-ABL mutations with altered oncogenic potency, kinase activity and substrate specificitySkaggs, B. J. / Kromsky, A. / Xie, Y. / Gorre, M. E. / Burgess, M. R. / Loo, J. / Sawyers, C. L. / Graeber, T. G. / Cold Spring Harbor Laboratory et al. | 2004
- 242
-
A role for cdk6 in cytoskeletal dynamics?Slomiany, P. / Grossel, M. J. / Cold Spring Harbor Laboratory et al. | 2004
- 243
-
Global gene expression profiling of circulating tumor cells (CTCs) and circulating endothelial cells (CECs) enriched from peripheral blood of patients with metastatic carcinomasSmirnov, D. A. / Zweitzig, D. R. / Foulk, B. W. / Miller, M. C. / Doyle, G. V. / Pienta, K. J. / Weiner, L. M. / Cohen, S. J. / Moreno, J. G. / Connelly, M. C. et al. | 2004
- 244
-
E-cadherin mediates cell-cell adhesion and suppression of anoikis during anchorage independent growth of Ewing tumor cellsSorensen, P. H. B. / Kang, H.-G. / Martin, M. J. / Triche, T. J. / Cold Spring Harbor Laboratory et al. | 2004
- 245
-
Analysis of different effects of Gli transcription factors on cellular transformationSparmann, A. / Valk-Lingbeek, M. / van Lohuizen, M. / Cold Spring Harbor Laboratory et al. | 2004
- 246
-
Deciphering the PI3K/PKB and TOR pathways in DrosophilaStocker, H. / Rottig, C. / Sulzer, A. / Oldham, S. / Wittwer, F. / Reiling, J. / Rintelen, F. / Gluderer, S. / Buser, N. / Werz, C. et al. | 2004
- 247
-
CLIC4 as a novel target for tumor therapySuh, K. S. / Yuspa, S. H. / Cold Spring Harbor Laboratory et al. | 2004
- 248
-
Human diploid fibroblasts are resistant to MEK/ERK-mediated disruption of the actin cytoskeleton and invasiveness stimulated by RasSukezane, T. / Oneyama, C. / Kakumoto, K. / Hanafusa, H. / Akagi, T. / Cold Spring Harbor Laboratory et al. | 2004
- 249
-
Identification of metastasis-associated genes in primary tumors of clear cell renal cell carcinomaSultmann, H. / Gunawan, B. / Haller, F. / Fuzesi, L. / Poustka, A. / Cold Spring Harbor Laboratory et al. | 2004
- 250
-
Large DNA palindromes as a common form of structural chromosome aberrations in human cancersTanaka, H. / Bergstrom, D. A. / Yao, M.-C. / Tapscott, S. J. / Cold Spring Harbor Laboratory et al. | 2004
- 251
-
Tumor reversion as an alternative approach in cancer research-Biological models, molecular pathways and identification of target proteins for potential cancer therapiesTelerman, A. / Amson, R. / Cold Spring Harbor Laboratory et al. | 2004
- 252
-
Spatio-temporal regulation of Raf as visualized by FRET-based probesTerai, K. / Matsuda, M. / Cold Spring Harbor Laboratory et al. | 2004
- 253
-
Genetic evidence for cooperative regulation of p53 activity by Mdm2 and Mdm4Terzian, T. / Van-Pelt, C. / Audiffred, A. / Lozano, G. / Cold Spring Harbor Laboratory et al. | 2004
- 254
-
Identification of a minimal set of transcripts from 1p and 19q involved in tumorigenesis of oligodendrogliomaTews, B. / Hoffmann, A. / Felsberg, J. / Hartmann, C. / Hahn, M. / Toedt, G. / Neben, K. / Hummerich, L. / von Deimling, A. / Reifenberger, G. et al. | 2004
- 255
-
Gene expression signature to predict clinical outcome of neoadjuvant chemotherapy in primary breast cancer and identification of new potential target genesThuerigen, O. / Schneeweiss, A. / Toedt, G. / Warnat, P. / Hahn, M. / Rudlowski, C. / Benner, A. / Brors, B. / Sohn, C. / Lichter, P. et al. | 2004
- 256
-
Mechanism of 4-HPR induced apoptosis in glioblastoma cellsTiwari, M. / Balapure, A. / Behari, S. / Sharma, R. / Kumar, A. A. / Sinha, R. A. / Shrivastava, A. / Godbole, M. M. / Cold Spring Harbor Laboratory et al. | 2004
- 257
-
How the RB tumor suppressor gene protects against hypoxia-induced cell deathTracy, K. / Dibling, B. / Spike, B. / Macleod, K. / Cold Spring Harbor Laboratory et al. | 2004
- 258
-
Loss of Rb leads to accumulation of chromosomal and nuclear abnormalities through ROS production in cells lacking proper cell cycle regulationTreanor, L. M. / Parker, M. / Xu, Z. / Lu, P. / Harrison, D. / Prost, S. / Cold Spring Harbor Laboratory et al. | 2004
- 259
-
Genetic ablation of Cyclin D1 abrogates genesis of rhabdoid tumors arising due to ini1/hSNF5 lossTsikitis, M. / Zhang, Z. / Edelman, W. / Zagzag, D. / Kalpana, G. V. / Cold Spring Harbor Laboratory et al. | 2004
- 260
-
Logical role of an RNA/DNA-binding protein SND1/TSN/p100 as a regulator of cell proliferationTsuchiya, N. / Nakashima, K. / Nakagama, H. / Cold Spring Harbor Laboratory et al. | 2004
- 261
-
Forward somatic cell genetic screens in mouse models of lymphoma and leukemiaUren, A. / Kool, J. / Matentzoglu, K. / Adams, D. / de Ridder, J. / Lacher, W. / Sie, D. / Lund, A. / Jonkers, J. / Bradley, A. et al. | 2004
- 262
-
Lymphoma development in Bax transgenic mice is associated with chromosomal instabilityvan de Wetering, C. I. / Le Beau, M. M. / Knudson, C. M. / Cold Spring Harbor Laboratory et al. | 2004
- 263
-
Analyzing the tumorigenic role of PLAG1 in vivoVan Dyck, F. / Declercq, J. / Van de Ven, W. / Cold Spring Harbor Laboratory et al. | 2004
- 264
-
Src inhibits adriamycin-induced senescence and G2 checkpoint arrest by blocking the induction of p21 waf1Vigneron, A. / Roninson, I. B. / Gamelin, E. / Coqueret, O. / Cold Spring Harbor Laboratory et al. | 2004
- 265
-
Distinct roles for ERK and Rac in regulating cyclin D1 expression and G1 phase progression of quiescent and cycling cellsVillanueva, J. / Castagnino, P. / Yin, L. / Roovers, K. / Assoian, R. K. / Cold Spring Harbor Laboratory et al. | 2004
- 266
-
BRAF^E^6^0^0 induces a p16^I^N^K^4^a-independent senescence-like arrest in primary human fibroblastsVredeveld, L. C. W. / Michaloglou, C. / Peeper, D. S. / Cold Spring Harbor Laboratory et al. | 2004
- 267
-
Meis1 programs transcription of FLT3 and leukemia stem cell character, using a mechanism that requires interaction with cofactor Pbx and a novel function of the Meis1 C-terminusWang, G. G. / Pasillas, M. P. / Kamps, M. P. / Cold Spring Harbor Laboratory et al. | 2004
- 268
-
Evidence for an essential pro-proliferative and anti-apoptotic role of the INK4 / CDK4,6 / Rb / E2F signaling pathway in AML with the Flt3 internal tandem duplicationWang, L. / Wang, J. / Blaser, B. / Caligiuri, M. A. / Briesewitz, R. / Cold Spring Harbor Laboratory et al. | 2004
- 269
-
Cyclin A1, a regulatory factor essential for male germ cell division plays a role in progression of prostate cancer via regulation of VEGF expression in cooperation with pRb- and androgen-mediated pathwayWegiel, B. / Bjartell, A. / Ekberg, J. / Gadaleanu, V. / Persson, J. L. / Cold Spring Harbor Laboratory et al. | 2004
- 270
-
Effect of polyamines on p53 acetylation and transcriptional activityWei, G. / Hobbs, C. / Gilmour, S. / Cold Spring Harbor Laboratory et al. | 2004
- 271
-
TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on Thr68Wei, J.-H. / Chou, Y.-F. / Ou, Y.-H. / Ye, Y.-S. / Tyan, S.-W. / Sun, T.-P. / Shen, C.-Y. / Shieh, S.-Y. / Cold Spring Harbor Laboratory et al. | 2004
- 272
-
p53 determines the response to targeted cancer therapyWendel, H.-G. / Ray, S. / Cepero, H. / Bornmann, W. G. / Kogan, S. C. / Lowe, S. W. / Cold Spring Harbor Laboratory et al. | 2004
- 273
-
A novel mitomycin DNA-adduct provokes alternative caspase p53-dependent and p53-independent apoptotic pathwaysWhite, D. E. / Abbas, T. / Talbott, K. E. / Berman, D. / Boamah, E. / Simpson, S. / Arva, N. C. / Tomasz, M. / Bargonetti, J. / Cold Spring Harbor Laboratory et al. | 2004
- 274
-
Mutant p53 reactivation by small molecules-A novel strategy for cancer therapyWiman, K. G. / Stridh, H. / Zache, N. / Rokaeus, N. / Issaeva, N. / Hammarsund, M. / Shen, J. / Westman, J. / Bergman, J. / Selivanova, G. et al. | 2004
- 275
-
Lymphangiogenesis is unnecessary for prostate cancer metastasis to lymph nodesWong, S. Y. / Haack, H. / Crowley, D. / Barry, M. / Bronson, R. T. / Hynes, R. O. / Cold Spring Harbor Laboratory et al. | 2004
- 276
-
Cooperation of Ras and mutant p53 in the control of cell motilityXia, M. / Land, H. / Cold Spring Harbor Laboratory et al. | 2004
- 277
-
An orphan G protein-coupled receptor, GPR56, plays important roles during metastasisXu, L. / Begum, S. / Crowley, D. / Hynes, R. / Cold Spring Harbor Laboratory et al. | 2004
- 278
-
Voltage-gated sodium channels and breast cancer metastasisYamaci, R. F. / Kaya, H. / Koyuturk, M. / Fraser, S. / Djamgoz, M. B. A. / Battaloglu, E. / Cold Spring Harbor Laboratory et al. | 2004
- 279
-
Screening zinc finger transcription factors for cancer-related function-Application of molecular and cellular biology methods on a genome-wide scaleYamada, N. A. / Segalle, K. D. / Hamilton, A. T. / Tran-Gyamfi, M. B. / Huntley, S. M. / Stubbs, L. J. / Cold Spring Harbor Laboratory et al. | 2004
- 280
-
Identification of vertebrate cell cycle regulated genes that are overexpressed in human liver cancerYang, C.-W. / Su, J.-Y. / Tsou, A.-P. / Liu, H.-L. / Chien, C.-Y. / Chou, C.-K. / Cold Spring Harbor Laboratory et al. | 2004
- 281
-
Mutations of the HBP1 transcriptional repressor are associated with invasive breast cancerYee, A. S. / Paulson, K. E. / Rieger-Christ, K. / Summerhayes, I. C. / McDevitt, M. A. / Huang, Z. / Kim, J. / Huang, C.-Y. / Kauffman, S. / Wazer, D. et al. | 2004
- 282
-
Representational oligonucleotide microarray (ROMA) identifies cIAP1/cIAP2 as candidate oncogenes in an orthotopic mouse model of hepatocellular carcinomaZender, L. / Spector, M. S. / Lucito, R. / Mu, D. / Flemming, P. / Hannon, G. / Cordon-Cardo, C. / Powers, S. / Lowe, S. W. / Cold Spring Harbor Laboratory et al. | 2004
- 283
-
PDGFR is a target of counter regulatory signaling in PI3K/PTEN-AKT-TSC-mTOR pathwayZhang, H. / Bajraszewski, N. / Wang, H. / Wang, J. / Dabora, S. / Kwiatkowski, D. J. / Cold Spring Harbor Laboratory et al. | 2004
- 284
-
Loss of p16^I^N^K^4^a provides a selective pressure and mechanism for loss of p53 in early cancerZhang, J. / Pickering, C. R. / Holst, C. R. / Gauthier, M. / Tlsty, T. D. / Cold Spring Harbor Laboratory et al. | 2004
- 285
-
Cooperation of activated K-Ras and pRb inactivation in astrocytoma progressionZhang, Q. / McCarthy, K. D. / Jacks, T. / Van Dyke, T. / Cold Spring Harbor Laboratory et al. | 2004
- 286
-
A novel function of artemis on cell cycle controlZhang, X. / Geng, L. / Yan, Y. / Legerski, R. J. / Cold Spring Harbor Laboratory et al. | 2004
- 287
-
Prostate-specific inactivation of p53 and Rb leads to metastatic cancer arising from the stem cell compartmentZhou, Z. / Flesken-Nikitin, A. / Corney, D. C. / Roy-Burman, P. / Nikitin, A. Y. / Cold Spring Harbor Laboratory et al. | 2004
- 288
-
The Syk tyrosine kinase localizes to the centrosomes and affects mitotic progression of human breast carcinoma cellsZyss, D. / Montcourrier, P. / Vidal, B. / Anguille, C. / Merezegue, F. / Lorca, T. / Mangeat, P. / Coopman, P. / Cold Spring Harbor Laboratory et al. | 2004
- 289
-
Use of a 3D basement membrane model of breast epithelial cells to investigate cellular processes that regulate oncogenesisBrugge, J. S. / Gao, G. / Reginato, M. / Mills, K. / Seton-Rogers, S. E. / Wrobel, C. / Lin, E. / Irie, H. Y. / Pearline, R. / Collins, N. et al. | 2004
- 290
-
Organ specific metastasis genesMassague, J. / Minn, A. J. / Gupta, G. P. / Siegel, P. M. / Bos, P. / Shu, W. / Giri, D. D. / Viale, A. / Olshen, A. / Gerald, W. L. et al. | 2004
- 291
-
Cancer-relevant Cullin-RING ubiquitin ligasesKaelin, W. G. / Harper, J. W. / Jin, J. / Kim, W. / Lee, S. / Reddy, A. / Safran, M. / Schlisio, S. / Wei, W. / Yang, H. et al. | 2004
- 292
-
The adaptor protein Tsk/Fish-Its role in podosome formation and function, and protease-driven invasion of cancer cellsSeals, D. F. / Azucena, E. F. / Pass, I. / Tesfay, L. / Gordon, R. / Resau, J. H. / Courtneidge, S. A. / Cold Spring Harbor Laboratory et al. | 2004
- 293
-
Regulation and multi-targeting of the angiogenic switch during tumorigenesisHanahan, D. / Casanovas, O. / Nozawa, H. / Giraudo, E. / Joyce, J. / Pietras, K. / Bergers, G. / Cold Spring Harbor Laboratory et al. | 2004
- 294
-
Hedgehog signaling in tissue regeneration, stem cell renewal, and neoplasiaBeachy, P. / Cold Spring Harbor Laboratory et al. | 2004
- 295
-
Two decades of cancer genetics-From specificity to pleiotropic networksPandolfi, P. P. / Cold Spring Harbor Laboratory et al. | 2004
- 296
-
Modeling tumors of the nervous system in mice to develop new therapeuticsParada, L. F. / Cold Spring Harbor Laboratory et al. | 2004
- 297
-
The genetic regulation of stem cell functionMorrison, S. / Cold Spring Harbor Laboratory et al. | 2004
- 298
-
Polycomb repressors controlling stem cell fate-Implications for cancer and developmentvan Lohuizen, M. / Cold Spring Harbor Laboratory et al. | 2004
- 299
-
Prostate stem cells and prostate cancer developmentXin, L. / Lawson, D. A. / Witte, O. N. / Cold Spring Harbor Laboratory et al. | 2004
- 300
-
Subversion of the Bcl-2 life/death switch in cancer development and therapyAdams, J. M. / Huang, D. C. S. / Strasser, A. / Willis, S. / Chen, L. / Wei, A. / Van Delft, M. / Michalak, E. / Kelly, P. / Bouillet, P. et al. | 2004
- 301
-
Cancer therapy based on the Ras pathwayMcCormick, F. / Macrae, M. / Tetsu, O. / Rodriguez-Viciana, P. / Phan, V. / Cold Spring Harbor Laboratory et al. | 2004
- 302
-
Deciphering cancer complexities in genetically engineered miceVan Dyke, T. / Hill, R. / Song, Y. / Zhang, Q. / Bash, R. / Simin, K. / Cardiff, R. / Yin, C. / Xiao, A. / Cold Spring Harbor Laboratory et al. | 2004
- 303
-
Kinase inhibitors in cancer-Lessons from chronic myeloid leukemia (CML)Sawyers, C. / Shah, N. / Gorre, M. / Burgess, M. / Skaggs, B. / Nicoll, J. / Tran, C. / Cold Spring Harbor Laboratory et al. | 2004
- 304
-
Correlations of mutations in EGFR and KRAS with clinical outcomes in NSCLCHillan, K. J. / Cold Spring Harbor Laboratory et al. | 2004
- 305
-
Development of CDK inhibitors as cancer therapeuticsLane, D. / Cold Spring Harbor Laboratory et al. | 2004
- 306
-
Biologically-derived nanoparticles as targeted microreservoir carriers for drugs and shRNA in cancerMacDiarmid, J. A. / Mugridge, N. B. / Weiss, J. C. / Phillips, L. / Dickson, K.-A. / Paulin, R. P. / Al Bakri, G. / Haasdyk, J. E. / Brahmbhatt, V. N. / Graham, R. M. et al. | 2004
- 307
-
Drugging the cancer kinomeWorkman, P. / Cold Spring Harbor Laboratory et al. | 2004
- 308
-
Application of protein microarrays and signal pathway profiling to individualized therapyPetricoin, E. F. / Espina, V. / Steinberg, S. / Yeung, C. / Eichler, G. / Krishnan, K. / Midura, B. / Tsokos, M. / Helman, L. / Liotta, L. et al. | 2004