438. Development of an siRNA Based Therapy for Hepatitis Virus Infection (Englisch)
- Neue Suche nach: Morrissey, D. V.
- Neue Suche nach: Blanchard, K.
- Neue Suche nach: Shaw, L.
- Neue Suche nach: Jensen, K.
- Neue Suche nach: Breen, W.
- Neue Suche nach: Zinnen, S.
- Neue Suche nach: Dickinson, B.
- Neue Suche nach: McSwiggen, J. A.
- Neue Suche nach: Vargeese, C.
- Neue Suche nach: Bowman, K.
- Neue Suche nach: Morrissey, D. V.
- Neue Suche nach: Blanchard, K.
- Neue Suche nach: Shaw, L.
- Neue Suche nach: Jensen, K.
- Neue Suche nach: Breen, W.
- Neue Suche nach: Zinnen, S.
- Neue Suche nach: Dickinson, B.
- Neue Suche nach: McSwiggen, J. A.
- Neue Suche nach: Vargeese, C.
- Neue Suche nach: Bowman, K.
In:
MOLECULAR THERAPY
;
11
;
170
;
2005
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ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:438. Development of an siRNA Based Therapy for Hepatitis Virus Infection
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Beteiligte:Morrissey, D. V. ( Autor:in ) / Blanchard, K. ( Autor:in ) / Shaw, L. ( Autor:in ) / Jensen, K. ( Autor:in ) / Breen, W. ( Autor:in ) / Zinnen, S. ( Autor:in ) / Dickinson, B. ( Autor:in ) / McSwiggen, J. A. ( Autor:in ) / Vargeese, C. ( Autor:in ) / Bowman, K. ( Autor:in )
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Erschienen in:MOLECULAR THERAPY ; 11 ; 170
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Verlag:
- Neue Suche nach: Elsevier Science B.V., Amsterdam
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Erscheinungsdatum:01.01.2005
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Format / Umfang:170 pages
-
ISSN:
-
Medientyp:Aufsatz (Zeitschrift)
-
Format:Print
-
Sprache:Englisch
- Neue Suche nach: 616.042
- Weitere Informationen zu Dewey Decimal Classification
-
Klassifikation:
DDC: 616.042 -
Datenquelle:
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Inhaltsverzeichnis – Band 11
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Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
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3. Effects of the cHS4 Insulator Elements on Transgene Expression and Biological Titer of Lentiviral VectorHanawa, H. / Shimada, T. et al. | 2005
- 1
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2. Cellular Mechanisms Involved with Lentiviral Gene TransferZhang, S. / Pollok, K. / Sastry, L. / Berthoux, L. / Luban, J. / Cornetta, K. et al. | 2005
- 1
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1. Persistent Gene Expression in Mouse Nasal Epithelia Following Baculovirus GP64 Pseudotyped FIV-Based Gene TransferSinn, P. L. / Burnight, E. R. / Hickey, M. A. / Blissard, G. W. / McCray, P. B. et al. | 2005
- 2
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4. Optimization of Globin Lentiviral Vector Design for the Treatment of β-ThalassemiaLisowski, L. / Rivella, S. / Sadelain, M. et al. | 2005
- 2
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5. Differential Expression of PIT1 and PIT2 after G-CSF Mobilization Is Associated with Efficient Gene Transfer Using GALV-Pseudotyped Gammaretroviral VectorsBeard, B. C. / Mezquita, P. / Morris, J. C. / Kiem, H. P. et al. | 2005
- 3
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6. In Vivo Adult Stem Cell Gene Transfer in Mice by In Situ Delivery of a Self-Inactivating Lentiviral Vector Using Intrafemoral InjectionWorsham, D. N. / Bohn, K. / Kuhel, D. / Williams, D. A. / von Kalle, C. / Pan, D. et al. | 2005
- 3
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8. Potent Inhibition of HIV-1 Replication by Lentiviral Vectors Carrying Anti-Vif siRNALi, S. / Wang, G. / Meinking, K. / Li, M. J. / Ji, J. / Zaia, J. A. / Rossi, J. J. et al. | 2005
- 3
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7. Transduction of Quiescent Human Cells Using an SIVsmmPBj-Derived Lentiviral VectorSchweizer, M. / Wolfrum, N. / Muehlebach, M. / Kaiser, J. / Schuele, S. / Cichutek, K. et al. | 2005
- 4
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mda-7/IL-24: Exploiting Cancer's Achilles' HeelLebedeva, I. V. / Sauane, M. / Gopalkrishnan, R. V. / Sarkar, D. / Su, Z. z. / Gupta, P. / Nemunaitis, J. / Cunningham, C. / Yacoub, A. / Dent, P. et al. | 2005
- 4
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10. The Effect of Globin Locus Control Region (LCR) Elements or the MSCV-LTR on Promoter Trapping by Integrated Lentiviral Vector GenomesRyu, B. Y. / Persons, D. A. / Nienhuis, A. W. et al. | 2005
- 4
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9. Coronaviruses: Development of Novel Oncolytic VectorsWürdinger, T. / Verheije, H. l. / van Beusechem, V. W. / de Haan, X. A. / Gerritsen, W. R. / Rottier, P. J. et al. | 2005
- 5
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13. Persistence of AAV Capsid in Transduced CellsHsieh, M. Y. / Khazi, F. R. / Schlachterman, A. / Liu, Y. L. / High, K. A. et al. | 2005
- 5
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12. Self-Complementary AAV2 Vectors Transduce Liver with the Same Efficiency as AAV8: The Critical Role of Second-Strand Synthesis in AAV BiologyWu, Z. / Duan, H. / Samulski, R. J. et al. | 2005
- 5
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11. An Additional Role of Cellular FKBP52 in Recombinant Adeno-Associated Virus 2 Vector-Mediated Gene Transfer and Transgene ExpressionZhao, W. / Zhong, L. / Wu, J. / Chen, L. / Qing, K. / Weigek-Kelley, K. A. / Larsen, S. H. / Srivastava, A. et al. | 2005
- 6
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15. Large-Scale Analysis of Adeno-Associated Virus Vector Integration Sites in Normal Human CellsMiller, D. G. / Trobridge, G. D. / Petek, L. M. / Jacobs, M. A. / Kaul, R. / Russell, D. W. et al. | 2005
- 6
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14. rAAV2 Integration Junctions Isolated without In Vivo Selection Bias Show a Preference to 5′ Regions of Open Reading FramesKhazi, F. R. / Schlachterman, A. / High, K. A. et al. | 2005
- 7
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16. Single-Polarity Recombinant Adeno-Associated Virus 2 Vector-Mediated Transgene Expression In Vitro and In Vivo: Mechanism of TransductionZhong, L. / Zhou, X. / Li, Y. / Qing, K. / Samulski, R. J. / Srivastava, A. et al. | 2005
- 7
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17. Visualization of the Intranuclear rAAV Replication Centers and Their Co-Localization with Double-Stranded DNA Break Repair ProteinsTiziana, C. / Zentilin, L. / Marcello, A. / Giacca, M. et al. | 2005
- 8
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19. rAAV-2 Transduction of Primitive Human Hematopoietic Stem Cells Capable of Serial Engraftment in Immune Deficient MicePaz, H. / Santat, L. / Li, L. / Wong, C. / Forman, S. J. / Wong, K. K. / Chatterjee, S. et al. | 2005
- 8
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20. Targeted Gene Delivery to Embryonic Stem CellsHenckaerts, E. / Zeltner, N. / Kattman, S. / Dutheil, N. / Ward, P. / Kennedy, M. / Clement, N. / Rebollo, P. / Keller, G. / Linden, R. M. et al. | 2005
- 8
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18. Facilitation of AAV Genome Circularization by Host Cell Factors Involved in DNA Replication and Double-Strand Break RepairChoi, V. W. / McCarty, D. M. / Samulski, R. J. et al. | 2005
- 9
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21. Application of Splice Acceptor Transposons to the Development of Oncolytic VirusesJin, F. / Kretschmer, P. / Chartier, C. / Kuhn, I. / Hermiston, T. et al. | 2005
- 9
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23. Frequency of Random and Targeted Chromosomal Integration of Helper-Dependent Adenoviral VectorOhbayashi, F. / Aizawa, E. / Kishimoto, A. / Mitani, K. et al. | 2005
- 9
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22. Generation of Circular Sleeping Beauty DNA Transposition Substrates by RU486-Induced Flp Recombination In Vitro – Steps towards a Single Integrating Adeno-Transposon VectorMikkelsen, J. G. / Yant, S. R. / Ehrhardt, A. / Kay, M. A. et al. | 2005
- 10
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24. Context-Specific Peptide-Presenting Phage Libraries for Adenoviral Vector TargetingGhosh, D. / Barry, M. A. et al. | 2005
- 10
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25. Genetic Incorporation of HSV-1 Thymidine Kinase into the Adenovirus Protein IX for Functional Display on the VirionLi, J. / Le, L. / Sibley, D. A. / Mathis, J. M. / Curiel, D. T. et al. | 2005
- 11
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27. A Novel "Geneti-Chemical" Platform for Flexible and Efficient De- and Retargeting of Adenovirus Vector ParticlesKreppel, F. / Gackowski, J. / Schmidt, E. / Kochanek, S. et al. | 2005
- 11
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28. Adenovirus Targeting Via Leucine Zipper Peptide-Mediated Ligand AttachmentGlasgow, J. N. / Korokhov, N. / Curiel, D. T. et al. | 2005
- 11
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26. Microsphere Delivery of Adenoviral-Liposome Complexes Reduces Adenoviral Immunogenicity and Allows Successful Re-Administration of the Virus without Loss of Gene Expression EfficiencySteel, J. C. / Morris, J. C. / Burton, M. A. / Cavanagh, H. M. / Kalle, W. H. et al. | 2005
- 12
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29. Redirection of Adenoviral Tropism through Capsomers Other Than Fiber Is Generally Inefficient and Dependent on Ligand-Receptor BiologyCampos, S. K. / Barry, M. A. et al. | 2005
- 12
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30. AdenoLibrary for Construction and Selection of Targeted AdenovirusesNoureddini, S. C. / Krendelshchikov, A. / Simonenko, V. / Douglas, J. T. / Curiel, D. T. / Korokhov, N. et al. | 2005
- 13
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32. Tolerance after Neonatal Gene Transfer of a Human Factor IX-Expressing Retroviral Vector May Involve Clonal Deletion in C3H Mice and Is Effective in Hemophilia B DogsXu, L. / Haskins, M. E. / Nichols, T. C. / Mei, M. / O'Donnell, P. / Bellinger, D. A. / McCorquodale, S. / Ponder, K. P. et al. | 2005
- 13
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31. Somatic Gene Therapy for ADA-SCID Following Cessation of PEG-ADA and Use of a Mild Conditioning RegimeGaspar, H. B. / Bjorkegren, E. / Parsley, K. / Gilmour, K. C. / Sinclair, J. / Zhang, F. / Fairbanks, L. D. / King, D. / Davies, G. / Veys, P. A. et al. | 2005
- 14
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33. Non-Random Genomic Distribution of Retrovirus Vector Integration in Successful SCID-X1 Gene TherapySchwarzwaelder, K. / Schmidt, M. / Howe, S. / Glimm, H. / Prinz, C. / Wissler, M. / Deichmann, A. / Schmidt, S. / Gaspar, B. / Thrasher, A. et al. | 2005
- 14
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34. Transposon-Based Gene Therapy of Hemophilia A Targeting Endothelial Cells in NeonatesLiu, L. / Fletcher, B. S. et al. | 2005
- 14
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35. Generalized Detoxification Associated with Engraftment of Gene-Corrected Repopulating Cells Achieved in ADA-SCID Patients by Stem Cell Gene Therapy without Myelopreparative Pre-ConditioningOtsu, M. / Nakajima, S. / Kida, M. / Maeyama, Y. / Toita, N. / Hatano, N. / Kawamura, N. / Okano, M. / Kobayashi, R. / Tatsuzawa, O. et al. | 2005
- 15
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37. A Novel Form of Enzyme Replacement Therapy for ADA-Deficiency: In Vivo Transduction by Neonatal Injection of Lentivirus Expressing ADACarbonaro, D. A. / Jin, X. / Petersen, D. / Kohn, D. B. et al. | 2005
- 15
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36. Improved Lentiviral Vectors for Systemic Gene Transfer in the Absence of an Immune ResponseBrown, B. D. / Hauben, E. / Lombardo, A. / Sergi, L. S. / Roncarolo, M. G. / Naldini, L. et al. | 2005
- 16
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38. Inhibition of Apolipoprotein B-100 Expression by Lentivirus Mediated RNA Interference in Mice after Stem Cell Transduction and TransplantationTurunen, M. P. / Makinen, P. I. / Leppanen, P. / Enback, J. / Koota, S. / Vatanen, T. / Yla-Herttuala, S. et al. | 2005
- 16
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39. Effects of Long-Term Expression of Activated Murine FVII in Normal and Hemophilic MiceAljamali, M. N. / Margaritis, P. / Camire, R. M. / High, K. A. et al. | 2005
- 17
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42. Uniform Scale-Independent Gene Transfer to Striated Muscle after Transvenular Extravasation of VectorGopal, K. / Su, L. T. / Wang, Z. / Yin, X. / Nelson, A. / Kozyak, B. W. / Burkman, J. M. / Mitchell, M. A. / Low, D. W. / Bridges, C. R. et al. | 2005
- 17
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41. High Efficiency, Catheter-Based, Gene Transfer to the Large Animal HeartKaye, D. M. / Chien, K. / Hoshijima, M. / Zsebo, K. / Power, J. et al. | 2005
- 17
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40. Enhanced Factor IX Delivery from Bioengineered Hybrid Human Skeletal Muscle Co-Expressing VEGFThorrez, L. / Vandenburgh, H. / Collen, D. / Shansky, J. / VandenDriessche, T. / Chuah, M. et al. | 2005
- 18
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44. Development of AAV-Mediated Gene Therapy for Murine Models of Genetic Diseases Affecting the HeartPacak, C. A. / Mah, C. / Gaidosh, G. / Lewis, M. / Torres, R. / Campbell, K. / Walter, G. A. / Byrne, B. J. et al. | 2005
- 18
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43. Targeting the Biology of Heart Disease: Engineered Zinc Finger Protein Repressors of Phospholamban as a Potential Therapy for Congestive Heart FailureZhang, H. S. / Zhang, L. / Huang, Y. / Liu, D. / Liang, Y. / Hickey, R. / Guschin, D. / Chandler, S. / Kunis, M. / Hinh, L. et al. | 2005
- 19
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46. In Vivo Adenoviral Gene Transfer of Activated PI3-Kinase Rescues Cardiac Dysfunction and Injury Induced by Ischemia-Reperfusion after Chronic Cardiac Akt ActivationNagoshi, T. / Matsui, T. / Aoyama, T. / Li, L. / Kass, D. A. / Champion, H. C. / Anthony, R. et al. | 2005
- 19
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Adenovirus Protein IX: A New Look at an Old ProteinParks, R. J. et al. | 2005
- 19
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45. Adenoviral Gene Transfer of SERCA2a Restores Mechanical and Energetic Left-Ventricular Function in Spontaneously Diabetic RatsSakata, S. / Sakata, Y. / Chemaly, E. R. / Padmanabhan, P. M. / Lebeche, D. / Takaki, M. / delMonte, F. / Hajjar, R. J. et al. | 2005
- 20
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47. Ex Vivo Hypothermic Recirculatory Adenoviral Gene Transfer to the Transplanted Pig HeartOi, K. / Davies, W. R. / Tazelaar, H. D. / Bailey, K. R. / Federspiel, M. J. / Russell, S. J. / McGregor, C. G. et al. | 2005
- 20
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48. The Long-Term Effects of SERCA2a Overexpression in Large Animal Model of Heart FailureKawase, Y. / Yoneyama, R. / Hoshino, K. / McGregor, J. / Ton-Nu, T. T. / Neilan, T. G. / Levine, R. A. / Hung, J. / Hayase, M. / del Monte, F. et al. | 2005
- 21
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49. Evaluation of Catheter-Based Deliveries of 10um Gelatin Hydrogel Microsphere, a Novel Non-Viral Vehicle, in a Porcine HeartHoshino, K. / Yoneyama, R. / Kawase, Y. / DeGrand, A. M. / Frangioni, J. V. / Tabata, Y. / Kimura, T. / Kita, T. / Hajjar, R. J. / Hayase, M. et al. | 2005
- 21
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50. Transcript Profiling Identifies Novel Role for SGK1 in Promoting Cardiomyocyte SurvivalAoyama, T. / Matsui, T. / Novikov, M. / Rosenzweig, A. et al. | 2005
- 22
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51. Adenoviral BDNF/Noggin-Induced Neurogenesis from Endogenous Neural Stem Cells Delays Motor Impairment and Extends Survival in a Transgenic Model of Huntington's DiseaseCho, S. R. / Chmielnicki, E. / Economides, A. / Goldman, S. A. et al. | 2005
- 22
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52. AAV-Delivered RNAi Improves Cellular and Motor Phenotypes in a Mouse Model for Huntington's DiseaseHarper, S. Q. / Staber, P. D. / He, X. / Martins, I. H. / Mao, Q. / Paulson, H. L. / Kotin, R. M. / Davidson, B. L. et al. | 2005
- 22
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53. Post-Transcriptional Suppression of Striatal Mutant Huntingtin Leads to Mild Phenotypic Improvements in the R6/1 MouseRodriguez, E. / Denovan-Wright, E. / Nash, K. / Lewin, A. S. / Mandel, R. J. et al. | 2005
- 23
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54. Lentiviral-Mediated Silencing of SOD1 through RNA Interference Delays Disease Onset and Progression in a Mouse Model of ALSRaoul, C. / Aebischer, P. et al. | 2005
- 23
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55. Lentiviral-Mediated Silencing of Mutant SOD-1 Using RNAi Causes Long Term Correction of ALS in a Transgenic Mouse ModelRalph, G. S. / Radcliffe, P. A. / Day, D. M. / Carthy, J. M. / Kingsman, S. M. / Mitrophanous, K. A. / Azzouz, M. / Mazarakis, N. D. et al. | 2005
- 23
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56. Amelioration of Neurodegenerative and Neuropathological Alterations in a Transgenic Model of Alzheimer's Disease: Targeting BACE1 with Small Interfering RNAsSinger, O. / Marr, R. A. / Rockenstein, E. / Crews, L. / Gage, F. H. / Verma, I. M. / Masliah, E. et al. | 2005
- 24
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57. Therapy for Alzheimer's Disease by Neprilysin Gene TransferMarr, R. A. / Rockenstien, E. / Mukherjee, A. / Kindy, M. S. / Hersh, L. B. / Gage, F. H. / Masliah, E. / Verma, I. M. et al. | 2005
- 24
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59. rAAV-Mediated Nigral Parkin Over-Expression Is Neuroprotective in the 6-OHDA Rat Model of Parkinson's DiseaseManfredsson, F. P. / Lewin, A. S. / Muzyczka, N. / Burger, C. / Mandel, R. J. et al. | 2005
- 24
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58. Rett Syndrome Is Reversible and Treatable by MeCP2 Gene Therapy into the Striatum in MiceKosai, K. i. / Kusaga, A. / Isagai, T. / Hirata, K. / Nagano, S. / Murofushi, Y. / Takahashi, T. / Takashima, S. / Matsuishi, T. et al. | 2005
- 25
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60. Recovery of Vestibular Function Induced by math1 Gene DeliveryStaecker, H. / Praetorius, M. / Brough, D. E. et al. | 2005
- 25
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61. Higher In Vivo Maintenance, Biodistribution and Immunopotency of Dendritic Cell Vaccines Self-Differentiated through Lentiviral Vector ProgrammingKoya, R. C. / Kimura, T. / Ribas, A. / Kasahara, N. / Stripecke, R. et al. | 2005
- 25
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62. Transduction of CD34+ Hematopoietic Progenitor Cells with a SIV-Based Lentiviral Vector Expressing Antisense SIV Env Protects CD4+ T Cell Progeny from SIVmac239 InfectionBraun, S. E. / Eng, F. / Connole, M. / Chen, C. / Dropulic, B. / Binder, G. K. / Lu, X. / Johnson, R. P. et al. | 2005
- 26
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Kupffer Cells and Not Liver Sinusoidal Endothelial Cells Prevent Lentiviral Transduction of Hepatocytesvan Til, N. P. / Markusic, D. M. / van der Rijt, R. / Kunne, C. / Hiralall, J. K. / Vreeling, H. / Frederiks, W. M. / Oude-Elferink, R. P. / Seppen, J. et al. | 2005
- 26
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64. Characterization of the Mechanism of Action of the Anti-HIV-1 Transgene F12-VifLupo, R. / Vallanti, G. / Federico, M. / Mavilio, F. / Bovolenta, C. et al. | 2005
- 26
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65. Protective Immunity Against Anthrax Lethal Toxin in Mice Immunized with an Ad-Based Vaccine Vector Expressing Lethal FactorBoyer, J. L. / Niven, T. B. / Hackett, N. R. / Crystal, R. G. et al. | 2005
- 26
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63. A Nonhuman Primate Model for Testing Immuno Gene Therapies for AIDS Using Gene-Protected T CellsSchmitz, J. E. / Hermann, F. / Newrzela, S. / Ricketts, M. / Schult-Dietrich, P. / Szyroki, A. / Johnson, R. P. / vonLaer, D. et al. | 2005
- 27
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67. Protective Immunity Against Yersinia pestis in Mice Immunized with an Ad-Based Vaccine Vector Expressing the Y. pestis F1 and V AntigensChiuchiolo, M. / Boyer, J. L. / Niven, T. / Krause, A. / Hackett, N. R. / Crystal, R. G. et al. | 2005
- 27
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68. Development of a Novel Non-Viral DNA Vaccine-Delivering Gene into the Nucleus of Dendritic CellsNakamra, T. / Kogure, K. / Moriguchi, R. / Futaki, S. / Fujimuro, M. / Yokosawa, H. / Seya, T. / Harashima, H. et al. | 2005
- 27
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66. A Protective Vaccine for the Rapid Response to Pandemic AVian InfluenzaGao, W. / Soloff, A. / Liu, X. / Montecalvo, A. / Matsuoka, Y. / Robbins, P. D. / Donis, R. O. / Katz, J. M. / Barratt-Boyes, S. / Gambotto, A. et al. | 2005
- 28
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70. Systemic Administration of siRNA Against EWS-FLI1 Using a Targeted, Non-Viral Formulation Inhibits Growth in a Disseminated Murine Model of Ewing's SarcomaHeidel, J. D. / Hu-Lieskovan, S. / Bartlett, D. W. / Triche, T. J. / Davis, M. E. et al. | 2005
- 28
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69. Tumor-Targeting Innumogene Therapy by Mesenchymal Stem Cells Expressing CX3CL1Xin, H. / Kanehira, M. / Mizuguchi, H. / Hayakawa, T. / Nukiwa, T. / Saijo, Y. et al. | 2005
- 29
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71. Intratumoral Delivery of Small Interfering RNA for Inhibition of Tumor Progression in MiceTakahashi, Y. / Nishikawa, M. / Takakura, Y. et al. | 2005
- 29
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72. Capsid Modifications Overcome Low Heterogeneous Expression of Heparan Sulfate Proteoglycan That Limits AAV2-Mediated Gene Transfer and Therapeutic Efficacy in Human Ovarian CarcinomaBartlett, J. S. / Shi, W. et al. | 2005
- 30
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73. Fully Retargeted Oncolytic Measles Viruses for Cancer TherapyNakamura, T. / Harvey, M. / Greiner, S. / Peng, K. W. / Russell, S. J. et al. | 2005
- 30
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74. Specific Delivery of hTRAIL and Inhibition of Ewing's Sarcoma Growth by Transplantation of Viral Vector-Transduced Bone Marrow-Derived Mesenchymal Stem Cells (MSC)Bartlett, J. S. / Shi, W. / Lawrencia, C. et al. | 2005
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76. New Strategy To Improve Imaging and Retargeting of HSV-1 VectorsGrandi, P. / McKee, T. D. / Mok, W. / Fernandez, J. L. / Breakefield, X. O. / Jain, R. K. et al. | 2005
- 31
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77. Efficient Transduction and Therapy of Malignant Glioma by Lentiviral Vectors Pseudotyped with LCMV GlycoproteinsMiletic, H. / Fischer, Y. / Neumann, H. / Giroglou, T. / Hermann, M. M. / Stenzel, W. / Rueger, M. A. / Waerzeggers, Y. / Himmelreich, U. / Hoehn, M. et al. | 2005
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75. Molecular Imaging of an EGFP-DRD2-Expressing Vaccinia VirusMehta, N. / Tang, N. / Deng, H. / Scollard, D. / Jonkman, J. / Wilson, B. C. / Reilly, R. M. / McCart, J. A. et al. | 2005
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78. Expression of the Herpes Simplex Virus Thymidine Kinase Gene by a Promoter Region of the Human SPARC Gene Inhibits Human Melanoma Cell Growth In Vitro and In VivoLopez, M. V. / Blanco, P. V. / Viale, D. L. / Cafferata, E. A. / Gould, D. / Chernajovsky, Y. / Podhajcer, O. et al. | 2005
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81. A Retrovirus Vector Screen for the Identification of Novel Chromatin Insulators and EnhancersGroth, A. C. / Stamatoyannopoulos, G. / Emery, D. W. et al. | 2005
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79. Real Time Fluorescent Tracking of Dynamic Variegation by Retrovirus Vectors in Stem CellsEllis, J. / Ramunas, J. / Kelly, L. / Sukonnik, T. / Jervis, E. et al. | 2005
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80. Insulation of Oncoretrovirus Vectors with the cHS4 Chromatin Insulator Is Associated with an Open Chromatin Histone CodeLi, C. / Emery, D. W. et al. | 2005
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82. Targeted Pancreatic Cancer-Specific Gene Therapy Controlled by a Molecular-Engineered Human Cholecystokinin Type-A Receptor (CCKAR) Promoter in In Vivo Imaging ModelsXie, X. / Li, Z. / Ding, Q. / Kuo, H. P. / Abbruzzese, J. L. / Hung, M. C. et al. | 2005
- 34
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83. Persistent and Position Independent Transgene Expression in Erythroid Cells Transduced by Lentiviral VectorsMiccio, A. / Lotti, F. / Rossi, C. / Ferrari, G. et al. | 2005
- 35
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84. Assessing Hemostatic Efficacy of Continuous Expression of Factor VIIa after AAV-Mediated, Liver-Directed Gene Transfer in Hemophilia A and B MiceSchlachterman, A. / Margaritis, P. / Aljamali, M. / Liu, J. / Arruda, V. / High, K. et al. | 2005
- 35
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86. Transcriptional Gene Silencing in Human CellsChen, Z. / Ehsani, A. / Art, R. / John, R. J. / Morris, K. V. et al. | 2005
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Liver-directed neonatal gene therapy prevents cardiac, bone, ear, and eye disease in mucopolysaccharidosis I miceLiu, Y. / Xu, L. / Hennig, A. K. / Kovacs, A. / Fu, A. / Chung, S. / Lee, D. / Wang, B. / Herati, R. S. / Mosinger Ogilvie, J. et al. | 2005
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85. Development of Zinc Finger Nucleases for Therapeutic Gene Correction of Sickle Cell AnemiaMiller, J. C. / Urnov, F. D. / Lee, Y. l. / Rock, J. / Sorba, T. / Patterson, S. / Gregory, P. D. / Holmes, M. C. / Rebar, E. J. et al. | 2005
- 36
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88. Driving shRNA Transcription from PolII Promoters in Mammalian CellsGiering, J. C. / Kay, M. A. et al. | 2005
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87. Determinants of Toxicity Induced by In Vivo Expression of Short Hairpin RNA from AAV VectorsGrimm, D. / Streetz, K. L. / Pandey, K. / Storm, T. A. / Kay, M. A. et al. | 2005
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89. Amelioration of Gamma Retroviral Silencing during Embryonic Stem Cell-Derived Hematopoiesis: Preclinical Assessment of Safety-Improved VectorsRamezani, A. / Hawley, T. S. / Hawley, R. G. et al. | 2005
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90. In Vitro and In Vivo Gene Expression of Lentiviral Vectors in CD4+ T CellsShaw, K. L. / Pepper, K. / Petersen, D. / Kaartinen, V. / Kohn, D. B. et al. | 2005
- 37
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91. Insertion of the cHS4-Insulator into Lentiviral Vectors: Use of Real-Time PCR in Order To Analyze the Effects on Transgene Expression and Viral TitreJakobsson, J. / Nielsen, T. T. / Rosenqvist, N. / Lundberg, C. et al. | 2005
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93. Diminished Mobilization of Self-Inactivating (SIN) Lentiviral Vectors Containing Globin Regulatory Elements Compared to Those Containing a Retroviral Long Terminal RepeatHanawa, H. / Persons, D. A. / Shimada, T. / Nienhuis, A. W. et al. | 2005
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94. Transgene Expression with Integration-Deficient HIV-1 Based Lentiviral Vectors Expressing Class I Integrase MutantsJoseph, G. / Marsh, J. / Johnson, T. / Cornetta, K. et al. | 2005
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92. Efficient Trangene Expression in Central Nervous System through a Non-Integrative Lentiviral VectorPhilippe, S. / Serguera, C. / Bonnel, S. / Vetu, C. / Barkats, M. / Petit, C. / Abitbol, M. / Sarkis, C. / Mallet, J. et al. | 2005
- 39
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96. Ocular Gene Transfer Using EIAV Vectors and an RPE-Specific PromoterKachi, S. / Binley, K. / Umeda, N. / Akiyama, H. / Lima e Silva, R. / Xiao, W. H. / Kachi, M. / Esapa, M. / Iqball, S. / Naylor, S. et al. | 2005
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95. Transduction and Expression of shRNAs Via Lentiviral Bectors Bearing a U6 RNA Polymerase III Promoter, but Not an H1 Promoter, Induce Elevated Apoptosis in Human Primary Peripheral Blood T LymphocytesAn, D. S. / Qin, X. F. / Mao, S. H. / Auyeung, V. C. / Baltimore, D. / Chen, I. S. et al. | 2005
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99. Use of a Liver-Specific Lentivirus Vector for Characterization of Hepatocyte-Like Cells from Human Differentiated Embryonic Stem Cells (hESC)Duan, Y. / Yamamoto, N. / Wu, J. / Gupta, S. / Zern, M. A. et al. | 2005
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98. Stable Lentivirus-Mediated RNA Interference: Comparison of U6 and H1 Promoters in Endothelial Cells and GFP Knockdown in Mouse BrainMakinen, P. I. / Koponen, J. K. / Turunen, A. M. / Malm, T. M. / Koistinaho, J. / Turunen, M. P. / Yla-Herttuala, S. et al. | 2005
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97. Type I Interferon Response Against Virus Vectors and Non-Viral Gene TransferPellinen, R. / Meriläinen, O. / Lehmusvaara, S. / Salonen, T. / Häkkinen, K. / Hakkarainen, T. / Vähäkangas, E. / Airenne, K. / Julkunen, I. / Hinkkanen, A. et al. | 2005
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100. Development of an Integrase Deficient FIV Vector for Transient Gene ExpressionBanasik, M. / Hickey, M. / McCray, P. et al. | 2005
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101. Development of Lentiviral Vectors with Respiratory Epithelial Specific Transgene ExpressionSenadheera, D. / Hendrickson, B. / Petersen, D. / Pepper, K. / Lutzko, C. et al. | 2005
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102. Overexpression of the Myostatin Antagonist Follistatin in Normal Myoblasts Genetically Modified with a LentivirusBenabdallah, B. F. / Rousseau, J. / Bouchentouf, M. / Tremblay, J. P. et al. | 2005
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104. Stable High Level Gene Expression by Minimum Sized Murine Leukemia Virus (MLV)-Based Retroviral Vectors in the Mouse ModelShin Yu, S. / Hong, Y. / Kim, S. / Joo, C. W. / Yoon, N. K. et al. | 2005
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103. PGK and CMV Promoters Exert the Strongest Activity in Lentiviral Gene Transduction of Myeloid Cells Including Mature NeutrophilsSoda, Y. / Tani, K. / Li, X. / Bai, Y. / Cho, S. G. / Futami, M. / Chen, M. / Kobayashi, S. / Miyoshi, H. / Sumimoto, H. et al. | 2005
- 43
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106. Measles Virus Host Defense Evasion Proteins V and C Have Also Transcription Modulation and Infectivity Factor FunctionsDevaux, P. / Songsungthong, W. / Springfeld, C. / von Messling, V. / Cattaneo, R. et al. | 2005
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105. Comparative Study on the Gene Expression Profile of HIV-1 Based Lentiviral Vectors Transduced Human and Murine CellsZhao, Y. / Azam, S. / Thorpe, R. et al. | 2005
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107. Sustained Stable Gene Expression Induced by a Cytoplasmic RNA-Virus Vector Based on Mutant Sendai Virus Strain cl.151Nishimura, K. / Segawa, H. / Goto, T. / Morishita, M. / Sakaguchi, T. / Yoshida, T. / Takayama, K. / Nakanishi, M. et al. | 2005
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108. The Complete Nucleotide Sequence of Sendai Virus Isolate BB1 and Comparison with Other IsolatesYang, Y. / Ren, L. / Dong, X. / Wu, X. et al. | 2005
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109. Expression of Porcine α(1–3)galactosyltransferase in Non-Human Primate Hematopoietic Progenitors Following Retroviral Mediated Gene TransferBenatuil, L. / Iacomini, J. et al. | 2005
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112. Strong Transgene-Specific Immune Responses Can Be Elicited with Novel Adeno-Associated Virus Vectors in MiceZhi, Y. / Johnston, J. / Wu, D. / Figueredo, J. / Lock, M. / Bell, P. / Gao, G. / Wilson, J. M. et al. | 2005
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111. AAV7, 8, and 9 Are More Efficient and Less Immunogenic Vectors for Muscle-Directed Gene Therapy for Hemophilia BWang, L. / Louboutin, J. P. / Li, Y. / Wilson, J. M. et al. | 2005
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110. Performance of Different AAV Serotype Vectors Following Injection into the Deep Cerebellar Nuclei of ASMKO Mouse BrainDodge, J. C. / Clarke, J. / Song, A. / Bu, J. / Zhao, Q. / Taksir, T. V. / Griffiths, D. / Shihabuddin, L. S. / O'Riordan, C. R. / Passini, M. A. et al. | 2005
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114. Efficient Arterial Formation at the Sites of Adult Neo-Angiogenesis Requires the Recruitment of Bone Marrow Cells through the Neuropilin-1 (NP-1) ReceptorZacchigna, S. / Arsic, N. / Pattarini, L. / Moimas, S. / Carrer, A. / Zentilin, L. / Salvi, A. / Sinagra, G. / Giacca, M. et al. | 2005
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113. Manipulating AAV2 Tropism for Enhanced Delivery of AAV Vectors to the Spinal CordDavis, A. / Stachler, M. / Shi, W. / Liu, J. / Boulis, N. / Bartlett, J. et al. | 2005
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115. In Vivo Expression of Human Cob(I)alamin Adenosyltransferase Using rAAV Serotypes 1,2 and 8, an Approach to Gene Therapy for Methylmalonic Aciduria (MMA)Erger, K. E. / Conlon, T. J. / Cossette, T. L. / Bobik, T. A. / Flotte, T. R. et al. | 2005
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116. Functional Comparison of Four CFTR rAAV Vectors with Alternative Transcriptional Elements in Cell Lines and Polarized Human CF Airway EpitheliaZhang, L. / Dutzar, B. / Munson, K. / Carter, B. / Engelhardt, J. F. et al. | 2005
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119. Intraperitoneal Transduction of Adeno-Associated Virus 2 Expressing Angiostatin and Endostatin Synergistically Augments Paclitaxel Therapy and Tumor-Free Survival in a Mouse Model of Epithelial Ovarian CancerIsayeva, T. / Ren, C. / Ponnazhagan, S. et al. | 2005
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Replacing acid α-glucosidase in Pompe disease: recombinant and transgenic enzymes are equipotent, but neither completely clears glycogen from type II muscle fibersRaben, N. / Fukuda, T. / Gilbert, A. L. / de Jong, D. / Thurberg, B. L. / Mattaliano, R. J. / Meikle, P. / Hopwood, J. J. / Nagashima, K. / Nagaraju, K. et al. | 2005
- 48
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117. AAV-Mediated Erythropoietin Gene Transfer Protects from Genetic and Light-Induced Retinal DegenerationAllocca, M. / Rex, T. S. / Domenici, L. / Bennet, J. / Rivera, V. M. / Auricchio, A. et al. | 2005
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118. Self-Complementary AAV Vectors Pseudotyped with Either Serotype 5 or 8 Capsids Give Therapeutic Human Factor IX Levels at Significantly Reduced Doses in Non-Human PrimatesGray, J. T. / Davidoff, A. M. / Nathwani, A. C. et al. | 2005
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120. Stimulation of the Synthesis of Type-II Collagen and Extracellular Matrix in Human Normal and Osteoarthritic Articular Cartilage Explants In Situ by Overexpression of Human sox9 by rAAV-Mediated Gene TransferMadry, H. / Thurn, T. / Kohn, D. / Terwilliger, E. F. / Cucchiarini, M. et al. | 2005
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121. VEGF-Induced Angiogenesis Does Not Have a Favorable Effect on Muscle Perfusion: A Relevant Role of Long-Term Angiopoietin-1 Expression in the Formation of Functional Blood VesselsZacchigna, S. / Tasciotti, E. / Arsic, N. / Sorace, O. / Cecilia, M. / Pardini, S. / Petroni, D. / Kusmic, C. / Pattarini, L. / Moimas, S. et al. | 2005
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122. Enhanced Expression of Glutamate Decarboxylase 65 Significantly Improves Rat Parkinsonian SymptomLee, B. / Nam, Y. R. / Kim, S. J. / Hwan Oh, J. / Choi, Y. H. / Chang, J. W. / Lee, H. et al. | 2005
- 50
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123. rAAV-pdx-1 Augmented the Insulin-Producing CellsLi, H. / Lam, K. S. / Tam, S. / Xiao, W. / Tam, P. / Xu, R. et al. | 2005
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124. The “Perivascular Pump? Driven by Arterial Pulsation Is a Powerful Mechanism for the Distribution of Therapeutic Molecules within the BrainHadaczek, P. / Mirek, H. / Tamas, L. / Bohn, M. C. / Noble, C. / Park, J. W. / Bankiewicz, K. et al. | 2005
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126. The Formation of Stable and Mature Blood Vessels Requires the Proper Timing of VEGF ExpressionTafuro, S. / Zacchigna, S. / Zentilin, L. / Dapas, M. / Giacca, M. et al. | 2005
- 51
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125. AAV Vector-Mediated Neonatal Gene Transfer: Efficient Transgene Expression in Muscles after Intraperitoneal Cavity Vector InjectionOgura, T. / Mizukami, H. / Mimuro, J. / Okada, T. / Hamada, H. / Kume, A. / Yoshikawa, H. / Sakata, Y. / Ozawa, K. et al. | 2005
- 51
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127. Intraarticular Gene Transfer of Rat TNFR:Fc Suppressed CIA ArthritisZhao, A. Z. / Gao, K. / Dong, X. Y. / Peng, J. Q. / Wu, X. B. et al. | 2005
- 52
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128. Transduction of Hepatic Oval Cells, Stem Cells, In Vitro by Adeno-Associated Virus VectorsYou, H. / Wang, P. / Jia, J. / Yong, L. / Hermonat, P. L. et al. | 2005
- 52
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130. Characterization of a Murine Adeno-Associated Virus (AAV-mo.1) CapsidLochrie, M. / Tatsuno, G. / Arbetman, A. / Smith, P. / Wellman, J. / Zhou, S. z. / Pierce, G. / Colosi, P. et al. | 2005
- 52
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129. Development of Vectors Utilizing Strong Neuronal Cell Type Specific Promoters for High Level Expression of Beta Glucuronidase in the Central Nervous SystemHusain, T. / Wolfe, J. H. et al. | 2005
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132. An Optimized CsCl Gradient -Based Method to Generate High Concentration AAV Vector Stocks of High Purity and In Vivo PotencyCooper, M. / Hauck, B. / Watkins, J. / Erne, M. / Mingozzi, F. / Herzog, R. / Wright, F. et al. | 2005
- 53
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131. Recombinant Adeno-Associated Virus 2-Mediated Transfer of the Human Superoxide-Dismutase Gene Does Not Confer Radioresistance on HeLa Cervical Carcinoma CellsVeldwijk, M. R. / Herskind, C. / Laufs, S. / Jens Zeller, W. / Fruehauf, S. / Wenz, F. et al. | 2005
- 54
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134. Toxicology and Biodistribution Studies of a Recombinant Adeno-Associated Virus 1 (rAAV1) Alpha-1 Antitrypsin (AAT) VectorPoirier, A. E. / Conlon, T. J. / Combee, L. A. / Erger, K. E. / Flotte, T. R. et al. | 2005
- 54
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133. Comparison of Adeno-Associated Viral Vector Serotypes 1, 2, 5 and 6 for Gene Transfer to Neurons and Glia In VitroHoward, D. B. / Li, J. / Wang, Y. / Harvey, B. K. et al. | 2005
- 54
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135. AAV-Mediated Gene Delivery To Evaluate the Biology of an Inherited Macular DegenerationKeiser, N. W. / Chung, D. C. / Tang, W. / Wei, Z. / Maguire, A. / Bennett, J. / Bennicelli, J. L. et al. | 2005
- 55
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136. Recombinant Adeno-Associated Virus 2-Mediated Ectopic Expression of α4β1 Integrin in Mouse Mesenchymal Stem Cells Enhances Repopulation to Bone upon Syngeneic Transplantation in an Immunocompetent Mouse ModelKumar, S. / Ponnazhagan, S. et al. | 2005
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137. Localization of Regions in CD46 That Interact with AdenovirusGaggar, A. / Shayakhmetov, D. M. / Liszewski, M. K. / Atkinson, J. P. / Lieber, A. et al. | 2005
- 55
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138. Blood Factors Affect Adenovirus Infectivity and Bio-Distribution In VivoShayakhmetov, D. M. et al. | 2005
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139. Priming and Boosting Efficiency of Chimp and Human Adenoviral Vectors in the Setting of Pre-Existing Immunity in Non-Human PrimatesFigueredo, J. / Calcedo, R. / Miller, J. / Kobinger, G. / Grant, R. / Gao, G. / Wilson, J. M. et al. | 2005
- 56
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140. Primary Adenovirus Specific Cytotoxic T Lymphocyte Response Occurs after Viral Clearance and Liver Enzyme ElevationChen, J. / Zajac, A. J. / McPherson, S. A. / Xu, X. / Yang, P. / Wu, Q. / Curiel, D. T. / Mountz, J. D. et al. | 2005
- 57
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Efficacy of an Adeno-associated Virus 8-Pseudotyped Vector in Glycogen Storage Disease Type IISun, B. / Zhang, H. / Franco, L. M. / Young, S. P. / Schneider, A. / Bird, A. / Amalfitano, A. / Chen, Y. T. / Koeberl, D. D. et al. | 2005
- 57
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141. Adenovirus Vaccine to Ebola Virus: Mechanism of Protection and Impact of Pre-Existing Immunity to the Vaccine CarrierKobinger, G. P. / Feldmann, H. / Zhi, Y. / Schumer, G. / Gao, G. / Feldmann, F. / Jones, S. / Wilson, J. M. et al. | 2005
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142. Molecular and Macromolecular Alterations of Recombinant Adenoviral Vectors Do Not Eliminate Changes in Hepatic Drug MetabolismCallahan, S. M. / Boquet, M. P. / Wonganan, P. / Croyle, M. A. et al. | 2005
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144. In Vivo Studies on the Toxicity of Adenovirus Vectors for Kupffer CellsManickan, E. / Smith, J. S. / Tian, J. / Byrnes, A. P. et al. | 2005
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145. Evaluation of Biodistribution and Safety of Adenovirus Vectors Containing B-Group Fibers after Intravenous Injection into BaboonsNi, S. / Bernt, K. / Li, Z. Y. / Kiem, H. P. / Lieber, A. et al. | 2005
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143. Regulated, High Capacity Adenoviral Vectors Mediated Long-Term Gene Expression in the Brain Even in the Presence of a Peripheral Immune Response to AdenovirusXiong, W. / Goverdhana, S. / Curtin, J. F. / Barcia-Gonzalez, C. / Zirger, J. M. / King, G. D. / Sciascia, S. A. / Puntel, M. / Candolfi, M. / Palmer, D. et al. | 2005
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147. Adenovirus Vector E4 Gene Regulates Connexin 40 and 43 Expression in Endothelial Cells Via PKA and PI3K Signal PathwaysCheng, J. / Zhang, F. / Lam, G. / Jin, D. / Vincent, L. / Hackett, N. R. / Wang, S. / Young, L. M. / Hempstead, B. / Crystal, R. G. et al. | 2005
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146. T Cell Response Against the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) GeneLimberis, M. / Figueredo, J. / Wilson, J. M. et al. | 2005
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148. The Transgene Cassette Is Not Fully Responsible for Alterations of Renal Cytochrome P450 Expression after Systemic Administration of Recombinant AdenovirusLe, H. T. / Boquet, M. P. / Clark, E. A. / Callahan, S. M. / Croyle, M. A. et al. | 2005
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149. Transient Kupffer Cell Saturation, Via Adenovirus or Adenoviral Protein, Enhances Expression of Reporter VirusMane, V. P. / Clarke, C. / Medina-Kauwe, L. / Finegold, M. / Lee, B. et al. | 2005
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150. Pre-Existing Nab and Neutralization of Therapeutic Dose Adenovirus Serotypes In VitroNwanegbo, E. C. / Gao, W. / Gambotto, A. / Robbins, P. et al. | 2005
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153. Adenoviral Gene Therapy Vectors Expressing the Adenovirus Death Protein Demonstrate Increased Transgene Expression In Vivo as Demonstrated by Dose-Volume Histogram Analysis of Reporter Gene ActivityBarton, K. N. / Brown, S. L. / Kim, J. H. / Stricker, H. / Karvelis, K. / Lu, M. / Freytag, S. O. et al. | 2005
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151. Evaluation of a Serotype 35 Fiber Containing Adenovirus Vector for VaccinationDi Paolo, N. C. / Ni, S. / Gaggar, A. / Li, Z. Y. / Lieber, A. et al. | 2005
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152. Coxsackievirus-Adenovirus Receptor (CAR) and αvβ3 or αvβ5 Integrin Independent Internalization of Porcine Adenoviral Vectors: Implications in Gene TherapyBangari, D. S. / Mittal, S. K. et al. | 2005
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154. Relationship between the Expression of Membrane Receptors (CAR, Integrin αvβ3 and Integrin αvβ5 ) and Adenoviral Transduction EfficiencyInoue, H. / Hisano, T. / Nakazaki, Y. / Sakaguchi, G. / Kurita, R. / Takayama, K. / Nakanishi, Y. / Tani, K. et al. | 2005
- 62
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156. Update on Genomic HSV Vector-Related Cytotoxicity: A Vector Preserving the Differentiation Potential of Embryonic and Adult Adipose Stem CellsFradette, J. / Wendell, S. K. / Wechuck, J. / Krisky, D. M. / Wolfe, D. / Goins, W. F. / Glorioso, J. C. et al. | 2005
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155. Oral Delivery of Recombinant Vaccinia Viruses Expressing Adjuvanted Islet Autoantigens Protects NOD Mice from Autoimmune DiabetesLangridge, W. H. / Denes, B. / Fodor, N. / Krausova, V. / Timiryasova, T. / Henderson, D. / Hough, J. / Yu, J. / Fodor, I. et al. | 2005
- 63
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157. Quantitation of Long-Term Gene Expression from the HSV-1 Latency-Associated Promoter in the Mouse Brain Following Intracranial InjectionBerges, B. K. / Gupta, A. / Wolfe, J. H. / Fraser, N. W. et al. | 2005
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158. Gene Therapy for Chronic Pain Control: Perspectives of HSV-1 Mediated Gene Transfer to Supraspinal CentresMartins, I. / Pinto, M. / Wilson, S. / Lima, D. / Tavares, I. et al. | 2005
- 64
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159. Unexpected Genetic Alterations Occur in Untargeted Genes during the Construction of Viral VectorsDambach, M. J. / Trecki, J. / Martin, N. / Markovitz, N. S. et al. | 2005
- 64
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160. Systemic Oncolytic Herpes Simplex Virus Therapy of Spontaneously Arising Prostate Cancer in Transgenic TRAMP MiceVarghese, S. / Rabkin, S. D. / Nielsen, P. G. / Liu, R. / Wang, W. / Martuza, R. L. et al. | 2005
- 65
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161. Targeting HSV Infection to gD Receptor-Negative Cells Using Soluble gD ReceptorsKwon, H. / Bai, Q. / Felmet, K. / Baek, H. J. / Kim, G. / Goins, W. F. / Cohen, J. F. / Glorioso, J. C. et al. | 2005
- 65
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162. Targeted HSV-1 Infection by Adapters for Glycoprotein D: Variable Infection Efficiency Dependent on Ligand ChoiceNakano, K. / Goins, W. F. / Cohen, J. B. / Glorioso, J. C. et al. | 2005
- 65
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163. Engineered of a Highly Efficient Cell Cycle Regulatable-HSV-1 Amplicon Viral VectorWang, G. Y. / Ho, I. A. / Hui, K. M. / Lam, P. Y. et al. | 2005
- 66
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165. Tracking of Baculovirus Biodistribution In Vivo by Magnetic Resonance ImagingRaty, J. K. / Wirth, T. / Airenne, K. J. / Huhtala, T. / Liimatainen, T. / Narvanen, A. / Hakumaki, J. / Yla-Herttuala, S. et al. | 2005
- 66
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164. Bioluminescence Imaging in the CNS after HSV Amplicon Vector DeliveryWang, S. / Pike, L. / Petravicz, J. / Breakefield, X. O. et al. | 2005
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Evaluation of polyethylene glycol modification of first-generation and helper-dependent adenoviral vectors to reduce innate immune responsesMok, H. / Palmer, D. J. / Ng, P. / Barry, M. A. et al. | 2005
- 66
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166. Recombinant Baculovirus Vectors Containing Inverted Terminal Repeats from Adeno-Associated Virus Improve Gene Expression in Neurons and AstrocytesYang Wang, C. / Wang, S. et al. | 2005
- 67
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169. The Creation of Novel Oncolytic Vaccinia Virus Vectors for Efficient Systemic Delivery of Transgenes to TumorsThorne, S. H. / Kirn, D. H. et al. | 2005
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168. Antitumoral Efficacy of Multiple Injection of JX-594 (Thymidine Kinase (TK) Deleted, Human GM-CSF Inserted Wyeth Strain) Via Tail Vein in N-Nitrosomorpholine (NNM) Treated RatsKim, J. s. / Kim, J. H. / Oh, J. y. / Park, B. h. / Yoon, J. H. / Thorne, S. H. / Kirn, D. H. / Hwang, T. h. et al. | 2005
- 67
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167. Both Oncolysis and Tumor Immunity Are Involved in an Autitumoral Efficacy by Intratumoral Injection of Recombinant Vaccinia Virus (TK Deleted, hGM-CSF Inserted Wyeth Strain) in a VX2 Rabbit ModelKim, J. H. / Park, B. H. / Oh, J. Y. / Kirn, D. H. / Thorne, S. H. / Kim, J. S. / Hwang, T. H. et al. | 2005
- 68
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171. Changing of Viral Tropism Alters Natural Proviral Property: Implications for Viral Vector DesignTan, P. H. / Xue, S. A. / Stuass, H. J. / George, G. J. et al. | 2005
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170. In Vitro Transduction of Cells To Determine Tropism Using Viral-Like Particles Derived from JC Virus VP1Cashion, L. / Ast, O. / Citkowicz, A. / Harvey, S. / Mitrovic, B. / Masikat, M. R. / Kauser, K. / Larsen, B. / Rubanyi, G. M. / Harkins, R. N. et al. | 2005
- 68
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172. In Vitro DNA Packaging and Gene Delivery Using JC Virus-Like ParticlesAst, O. / Citkowicz, A. / Cashion, L. / Larsen, B. / Rubanyi, G. M. / Harkins, R. N. / Petry, H. et al. | 2005
- 69
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173. Process Design and Scale-Up of New Vaccine Concepts for BiodefenseHerzer, S. U. / Bergvall, P. / Lemmens, R. / Coffey, M. / Leps, W. T. / Moore, P. M. et al. | 2005
- 69
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174. Process Development of a Scaleable Purification Protocol for the Production of Reolysin, an Oncolytic, Reovirus-Based TherapeuticHerzer, S. U. / Peder, B. / Raf, L. / Matt, C. / Peter, M. M. et al. | 2005
- 69
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176. Target-Site Preferences of Sleeping Beauty Transposons in an Intron of the B-raf OncogeneBell, J. B. / Hackett, C. S. / Geurts, A. M. / Carlson, C. M. / Collier, L. S. / Liu, G. / Largaespada, D. A. / Hackett, P. B. et al. | 2005
- 69
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175. Titering Gene Delivery Vectors by QPCR: Application to rSV40-Derived VectorsMitchell, C. B. / Strayer, D. S. et al. | 2005
- 70
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178. A Novel RNA Quantitation Method Using Hydrophobic Interaction Chromatography-High Performance Liquid ChromatographyJohnson, S. / Doig, A. / Hebel, H. / Gonzalez, H. / Attra, H. et al. | 2005
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177. Analysis of the High Shear Cell Lysis Device and the Air-Mixed Neutralization Column Used in the Recovery of Plasmid DNA from E. coli CellsRamakrishnan, S. / Gonzalez, H. / Hebel, H. L. et al. | 2005
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179. Transgenesis of B Lymphocytes by Bacterial DNA Is TLR9 IndependentGerloni, M. / Wheeler, M. / Cortez-Gonzales, X. / Pellicciotta, I. / Zanetti, M. et al. | 2005
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180. pDNAVACC Vector Family: High Throughput Intracellular Targeting DNA Vaccine Plasmids Created by Gene Self AssemblyWilliams, J. A. / Luke, J. / Johnson, L. / Hodgson, C. P. et al. | 2005
- 71
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182. An Effective and Valuable Process Using Disposable Membrane-Based Technologies for Pure Plasmid DNA Isolation and Purification: Throughput, Quality, and Cleaning Validation AdvantagesGonzalez, H. L. / Ramakrishnan, S. / Johnson, S. / Doig, A. / Hebel, H. L. et al. | 2005
- 71
-
183. Development of Ex-Vivo Gene Therapy Procedures for Central Nervous System Diseases, Based on Homologous Recombination in Human Neural Stem CellsLopez, C. A. / Serrano, A. M. et al. | 2005
- 71
-
181. The Effect of Dissolved Oxygen Fluctuations on Cell Growth and Plasmid YieldRamakrishnan, S. / Miller, J. / Darnell, J. / Hebel, H. L. et al. | 2005
- 72
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185. Poly-lactide-co-glycolide Acid (PLGA) Nanoparticles for DNA VaccinationGvili, J. / Machluf, M. et al. | 2005
- 72
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184. Nonvirally Electrotransfected Human Mesenchymal Stem Cells: A Novel Platform for Bone Gene Therapy Based on Autocrine and Paracrine MechanismsAslan, H. / Zilberman, Y. / Li, J. Z. / Helm, G. A. / Gazit, Z. / Gazit, D. et al. | 2005
- 73
-
187. Strategies of Intravascular Delivery of Naked DNA into Rat Skeletal MuscleJia, Z. / Dankó, I. n. et al. | 2005
- 73
-
186. Secreted Extracellular Vesicles of Baculovirus GP64 Interact with Plasmid DNA to Enhance TransfectionGuibinga, G. H. / Hinton, A. C. / Miyanohara, A. / Friedmann, T. et al. | 2005
- 74
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190. Improvement of Electroporation Devices and Methods for Use with Plasmid-Based Therapeutics and DNA Vaccine Applications in Small and Large AnimalsKhan, A. S. / Draghia-Akli, R. et al. | 2005
- 74
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188. Transfer of DNA in Tissues Using Local Fast InjectionAndre, F. M. / Cournil-Henrionnet, C. O. / Opolon, P. / Mir, L. M. et al. | 2005
- 74
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189. Improvement of In-Vivo Transfer of Plasmid DNA in Muscle: Comparison of Electroporation Versus UltrasoundHospers, G. A. / Dam, W. A. / DeBaets, M. H. / Losen, M. H. / Meijer, C. / Mulder, N. H. et al. | 2005
- 75
-
192. Non-Viral, Long-Term Gene Expression in Hematopoietic Cells Using the Sleeping Beauty Transposon SystemLiu, L. N. / Essner, J. J. / Shivakumar, R. / Li, L. / Wadman, S. A. / Clark, K. J. / Nasevicious, A. / Fratantoni, J. C. / McIvor, R. S. / Hackett, P. B. et al. | 2005
- 75
-
191. Identification of a Novel Functional Domain in the Sleeping Beauty Transposase: Towards Alleviating the Restriction of SB Overproduction InhibitionPark, J. / Yant, S. R. / Kay, M. A. et al. | 2005
- 76
-
193. Direct Comparison of Integration Efficiency and Stable Gene Expression Mediated by the Sleeping Beauty Transposon System and by the PhiC31 Phage Integrase System in Cultured Human Fibroblasts and in Various Stem Cell TargetsWilber, A. / Montoya, F. / Geurts, A. M. / Largaespada, D. A. / Lakshmipathy, U. / McIvor, R. S. et al. | 2005
- 76
-
195. Non-Viral, Site-Specific Gene Transfer into Murine Hematopoietic Stem CellsHoyt, J. J. / Keravala, A. / Duda, J. / Contag, C. H. / Calos, M. P. et al. | 2005
- 76
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194. Characteristics of Site-Specific Integration as Mediated by PhiC31 Integrase in the Human GenomePortlock, J. L. / Chalberg, T. W. / Olivares, E. C. / Thyagarajan, B. / Kirby, P. J. / Calos, M. P. et al. | 2005
- 77
-
196. Role of Kupffer Cells in Hepatic Transgene Expression Mediated by Intrabiliary Infusion of Nonviral VectorsDai, H. / Jiang, X. / Chen, Y. / Mao, H. Q. / Leong, K. W. et al. | 2005
- 77
-
197. Hepatocyte-Specific Delivery of Short Interfering RNAs Using Reducible PolycationsStevenson, M. / Liu, W. l. / Singh, S. / Preece, J. A. / Briggs, S. S. / Tilapur, U. / Read, M. L. / Seymour, L. W. et al. | 2005
- 78
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199. Efficient Inhibition of Bone Metastasis Via Systemic Delivery of siRNA Using Atelocollagen-Mediated Delivery SystemNagahara, S. / Takeshita, F. / Honma, K. / Minakuchi, Y. / Sano, A. / Ochiya, T. et al. | 2005
- 78
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198. Design and Testing of Intrinsic Proteasome Inhibitors To Increase Gene Transfer EfficiencySinclair, M. E. / Kim, J. s. / Chen, C. / Liu, D. / Rice, K. G. et al. | 2005
- 79
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200. Factor VIII Gene Expression after Catheter-Based DNA Nanoparticle DeliveryBowman, K. / Du, X. / LeVisage, C. / Sarkar, R. / Yang, X. / Leong, K. W. et al. | 2005
- 79
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201. C105Y, a Novel Cell Penetrating Peptide Enhances Gene Transfer of Sec-R Targeted Molecular ConjugatesRhee, M. / Davis, P. B. et al. | 2005
- 79
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202. DNA Delivery to the Mitochondria Sites Using Leader Peptide Conjugated PolyethylenimineLee, M. / Choi, J. S. / Ko, K. S. et al. | 2005
- 80
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Hsp70 Gene Transfer by Adeno-associated Virus Inhibits MPTP-Induced Nigrostriatal Degeneration in the Mouse Model of Parkinson DiseaseDong, Z. / Wolfer, D. P. / Lipp, H. P. / Büeler, H. et al. | 2005
- 80
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204. Substrate-Mediated Gene Delivery for Assessment of Signal Transduction Pathways in Cancer CellsPannier, A. K. / Bengali, Z. / Ariazi, E. A. / Jordan, V. C. / Shea, L. D. et al. | 2005
- 80
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203. Gene Transfer Activity Is Enhanced Significantly by Allowing Cationic Polymer to Interact with Serum Proteins prior to DNA AdditionConwell, C. C. / Liu, F. / Huang, L. et al. | 2005
- 81
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205. Quantitative Analysis of Non-Viral Gene Therapy in a Three-Dimensional Liver BioreactorTedford, N. C. / Fang, J. / Huang, B. / Domansky, K. / Griffith, L. G. / Lauffenburger, D. A. et al. | 2005
- 81
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206. Intracellular Signal-Responsive Gene Carrier for Cell-Specific Gene TherapyKatayama, Y. / Kang, J. H. / Kodama, K. / Oishi, J. / Niidome, T. et al. | 2005
- 81
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207. Anti-GAD Antibody Targeted Non-Viral Gene Delivery to Islet Beta CellsJeong, J. H. / Lee, M. / Kim, W. J. / Yockman, J. W. / Park, T. G. / Kim, Y. H. / Kim, S. W. et al. | 2005
- 82
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209. Nuclear Localization Mediated by the Adenoviral-Core Peptide Mu Enhances Phage φC31-Integrase Activity in Mammalian CellsHarbottle, R. P. / Vaysse, L. / Rahim, A. / Kienast, Y. / Passa, O. / Tolmachov, O. / Coutelle, C. et al. | 2005
- 82
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208. Physicochemical and Biological Characterization of Cyclodextrin-Based Polycation (CDP)/siRNA Composites Designed for Systemic DeliveryBartlett, D. W. / Heidel, J. D. / Davis, M. E. et al. | 2005
- 82
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210. Intracellular Disassembly and Transcription Efficiency of Polyplexes Delivered into Cells Using Novel Self-Assembling Gene CarriersYamaoka, T. / Hashimoto, T. / Kitagawa, T. / Murakami, A. et al. | 2005
- 83
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212. Differential, Transient Transduction of Defined Human Stem Cell Subsets Using Nanoparticles in a Clinically Applicable Ex Vivo ProtocolBonde, J. / Maxwell, D. J. / Hess, D. A. / Lahey, R. / Piwnica-Worms, D. / Nolta, J. A. et al. | 2005
- 83
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211. Novel Fiber-Mediated Adenovirus Interactions in Primary Rabbit Lacrimal AciniXie, J. / Rentsendorj, A. / Agadjanian, H. / Medina-Kauwe, L. K. / Hamm-Alvarez, S. F. et al. | 2005
- 84
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213. PEG-Modified Cationic Gold Nanoparticles and Their Abilities of In Vivo Gene DeliveryKawano, T. / Niidome, Y. / Katayama, Y. / Niidome, T. et al. | 2005
- 84
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214. HVJ-E/Importin β Hybrid for Efficient Gene DeliveryNagasaki, T. / Kawazu, T. / Shinkai, S. et al. | 2005
- 85
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217. Synthesis and Characterization of a Smart Triblock Copolymer Carrier for siRNASegura, T. / Hubbell, J. A. et al. | 2005
- 85
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215. Investigating Urokinase Plasminogen Activator Receptor (CD87), as a Potential Target for Non-Viral Gene TransferThanou, M. / Kean, T. et al. | 2005
- 85
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216. Enhancement of Gene Transfection Both In Vitro and In Vivo Using Polymer Conjugated HVJ-Envelope VectorMima, H. / Tomoshige, R. / Tabata, Y. / Yamamoto, S. / Ito, S. / Tamai, K. / Kaneda, Y. et al. | 2005
- 86
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219. Development of a Polyethylene Glycol Gene Delivery VehicleKohrt, N. M. / Grabski, L. E. / Sakiyama-Elbert, S. E. et al. | 2005
- 86
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218. Soluble Flt-1 Gene Delivery Using PEI-g-PEG-RGD Conjugate for Anti-AngiogenesisKim, W. J. / Yockman, J. W. / Lee, M. / Jeong, J. H. / Kim, Y. H. / Kim, S. W. et al. | 2005
- 87
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220. Long-Term Implantation of Photo-Crosslinked Alginate MicrocapsulesShen, F. / Li, A. A. / Potter, M. A. / Chang, P. L. et al. | 2005
- 87
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221. Spermine-Grafted Hyaluronic Acid as Multifunctional Coating of the Plasmid/Polycation Complex for Protection, Targeting, and Transcriptional ActivationIto, T. / Iida-Tanaka, N. / Kubo, K. / Yoshikawa, K. / Koyama, Y. et al. | 2005
- 88
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223. In Vitro Gene Transfer from a DNA-PEI Loaded Polylactide-Glycolide Porous SpongeRettig, G. R. / Oyeyumi, M. / Huang, Y. C. / Rice, K. G. et al. | 2005
- 88
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224. Novel Receptor-Mediated Gene Transfection Systems Comprising Plasmid / Polycation / RGD-PEG-COOH Ternary ComplexesSakae, M. / Ito, T. / Tanaka, N. I. / Koyama, Y. et al. | 2005
- 88
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222. Enhancement of Intracellular Gene Delivery by the S413-PV Cell Penetrating PeptideMano, M. / Teodósio, C. / Paiva, A. / Simões, S. r. / Pedroso de Lima, M. C. et al. | 2005
- 89
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225. Characterization and Evaluation of Branched and Linear Polyethyleneimine Conjugated PLGA Microparticles for Applications in DNA Vaccine DeliveryKasturi, S. P. / Sachabhipulkij, K. / Roy, K. et al. | 2005
- 89
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Lentiviral-Mediated Delivery of Bcl-2 or GDNF Protects against Excitotoxicity in the Rat HippocampusWong, L. F. / Scott Ralph, G. / Walmsley, L. E. / Bienemann, A. S. / Parham, S. / Kingsman, S. M. / Uney, J. B. / Mazarakis, N. D. et al. | 2005
- 89
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226. Transcription- Activating Effect of the Synthetic Water-Soluble PolyampholytesYamashita, M. / Ito, T. / Iida-Tanaka, N. / Koyama, Y. et al. | 2005
- 90
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228. Secretory PTD Fusion ProteinsShaw, P. A. / Catchpole, I. R. / Colledge, W. H. et al. | 2005
- 90
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227. Functionalized Multi-Block Co-Polymers of Short Length Linear Polyethylenimines for Safe and Efficient Gene TransferSlobodkin, G. / Matar, M. / Ramsey, A. / Fewell, J. / Brunhoeber, E. / Anwer, K. et al. | 2005
- 91
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230. The Study on Chitosan Nanoparticles as New Gene Delivery SystemSun, M. / Zhang, H. / Zhang, B. et al. | 2005
- 91
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229. Development of a Novel Drug Delivery System Based on Intrapericardial Administration of Plasmid DNA in a Thermosensitive Gel FormulationRoques, C. / Salmon, A. / Serose, A. / Fattal, E. / Fromes, Y. Y. et al. | 2005
- 91
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232. Gene Therapy for Deficient Cholesterol Synthesis in a Mouse Model of SLOSBuddhikot, M. / Marcos, J. / Tabron, D. / Porter, F. / Shackleton, C. / Watson, G. et al. | 2005
- 91
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231. Fluorescent Tracking of Non-Viral Gene DeliveryJaffar, S. / Belcher, A. et al. | 2005
- 92
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234. Polyclonal Insertion Sites in Two Rhesus Macaques after Non-Myeloablative Transplantation with MFGS-gp91phox Transduced Autologous CD34+PBPCBrenner, S. / Ryser, M. F. / Choi, U. / Whiting-Theobald, N. / Linton, G. / Kang, E. / Lehmann, R. / Farese, A. M. / MacVittie, T. J. / Roesler, J. et al. | 2005
- 92
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233. Towards Reversing Sandhoff Pathology by Lentiviral-Mediated Gene TherapyArfi, A. / Ziesling, R. / Poenaru, L. / Futerman, A. / Caillaud, C. et al. | 2005
- 93
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235. The Route of Vector Delivery Impacts the Therapeutic Effects of AAV-Mediated Gene Therapy in Adult Mucopolysaccharidosis IIIB MiceFu, H. / Kang, L. / Moy, S. S. / Jennings, J. S. / Perez, A. / Muenzer, J. et al. | 2005
- 93
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237. Evaluation of Low-Level, Constitutive Expression of β-glucuronidase on the Clinical Manifestations of Mucopolysaccharidosis Type VIIDonsante, A. / Levy, B. / Vogler, C. / Sands, M. et al. | 2005
- 93
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236. Bone Marrow-Derived Cells Do Not Contribute to Endocrine Pancreas Regeneration in Diabetic RIP/IGF-I Transgenic MiceAyuso, E. / Jimenez, V. / Agudo, J. / Haurigot, V. / Segovia, J. C. / Bueren, J. / Bosch, F. et al. | 2005
- 94
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238. Stem Cell Gene Delivery to Immunocompetent Mice Using a Non-Myeloablative Regimen Results in Long-Term Transgene Expression and Stable Mixed ChimerismBigger, B. W. / Waddington, S. N. / Buch, M. / Nivsarkar, M. / Jones, N. / Watt, S. M. / Wood, K. / Themis, M. et al. | 2005
- 94
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239. Immunomodulation Is Necessary to Achieve Stable Expression after Retroviral Vector-Mediated Liver-Directed Gene Therapy to Adult Mice with MPS IMa, X. / Xu, L. / Liu, Y. / Wang, B. / Ponder, K. P. et al. | 2005
- 95
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241. Gene Expression in the Striatum of HPRT Knockout MiceShaochun, S. / Theodore, F. et al. | 2005
- 95
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242. The Use of AAV Serotype 1 Vector for Expression of α-Galactosidase A in Fabry Knockout MiceOgawa, K. / Hirai, Y. / Zenri-Aihara, K. / Fukunaga, Y. / Shimada, T. et al. | 2005
- 95
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240. Intramuscular Administration of an AAV Vector Expressing 4-Sulfatase (4S) to Newborn Cats With Mucopolysaccaridosis VI: Sulfatase Activity in Muscle, Serum, and LiverHaskins, M. / O'Malley, T. / Wang, P. / Cullen, K. / Traas, A. / Tessitore, A. / Doria, M. / Auricchio, A. et al. | 2005
- 96
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Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion modelKurozumi, K. / Nakamura, K. / Tamiya, T. / Kawano, Y. / Ishii, K. / Kobune, M. / Hirai, S. / Uchida, H. / Sasaki, K. / Ito, Y. et al. | 2005
- 96
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243. Transplantation of Neonatal NOD/SCID/MPSVII Mice with Human Mesenchymal Stem CellsHerrbrich, P. E. / Meyerrose, T. E. / Hofling, A. A. / Sands, M. / Nolta, J. A. et al. | 2005
- 96
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244. AAV Vector-Mediated Gene Therapy of Mucopolysaccharidosis Type IBelur, L. / Lorenzo, D. / Aronovich, E. / Low, W. C. / Whitley, C. B. / McIvor, R. S. et al. | 2005
- 96
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245. AAV2/8-Mediated Efficacy and Immune Tolerance in a Pompe Disease Mouse ModelBercury, S. D. / Ziegler, R. J. / Barbon, C. M. / Souza, D. / Armentano, D. / Thurberg, B. L. / Taksir, T. / Do, H. / Trout, M. / Raben, N. et al. | 2005
- 97
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246. Comparison of rAAV2-Mediated Expression of Human and Murine β-Glucuronidase in Adult MPS VII MiceGreathouse, K. / Wang, C. M. / Sferra, T. J. et al. | 2005
- 97
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247. Gene Therapy with a Retroviral Vector Expressing Canine β-Glucuronidase to Juvenile (7 Week Old ) Dogs Improves the Biochemical Manifestations of MPS VIIWang, B. / Wang, P. / O'Malley, T. / Xu, L. / Haskins, M. E. / Ponder, K. P. et al. | 2005
- 98
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249. Minimal Dose of AAV8/DC190-ASM Necessary for Therapeutic Efficacy in a Mouse Model of Niemann-Pick DiseaseZiegler, R. J. / Barbon, C. M. / Bercury, S. D. / Hawes, M. L. / Schuchman, E. H. / Desnick, R. J. / Cheng, S. H. et al. | 2005
- 98
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250. Correction of Hunter Syndrome in the Ids-Knock-Out Mouse Model by r-AVV Mediated Gene TherapyCardone, M. / Polito, V. / D'Azzo, A. / Muenzer, J. / Auricchio, A. / Ballabio, A. / Cosma, M. P. et al. | 2005
- 98
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248. A Mouse Model of Type VII Glycogenosis to Assay Gene Therapy ApproachesBosch, F. / Garcia, M. / Pujol, A. / Ruzo, A. / Arbos, A. / Feliu, J. E. et al. | 2005
- 99
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253. An AAV Vector-Mediated Gene Transfer into Canine Skeletal MuscleIkemoto, M. / Yuasa, K. / Yoshimura, M. / Nishiyama, A. / Miyagoe-Suzuki, Y. / McC Howell, J. / Takeda, S. i. et al. | 2005
- 99
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252. A Novel Approach of Gentamicin Therapy for Duchenne Muscular Dystrophy Using Hybrid Liposome and Establishment of a System To Identify the Patients Eligible for the TreatmentKimura, S. / Ito, K. / Ozasa, S. / Kawano, H. / Ikezawa, M. / Matsukura, M. / Ueoka, R. / Matsumoto, Y. / Matsuo, M. / Takeshima, Y. et al. | 2005
- 99
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251. Dystrophin in Vascular Smooth Muscle Is Important for Duchenne Muscular Dystrophy TherapyIto, K. / Kimura, S. / Thomas, G. D. / Ozasa, S. / Matsukura, M. / Ikezawa, M. / Ueno, H. / Yoshioka, K. / Suzuki, M. / Miwa, T. et al. | 2005
- 100
-
255. Embryonic Stem Cell-Mediated Regenerative Therapy for Duchenne Muscular DystrophyOzasa, S. / Kimura, S. / Matsukura, M. / Ito, K. / Ikezawa, M. / Kawano, H. / Miike, T. / Yamamura, K. / Araki, K. / Abe, K. et al. | 2005
- 100
-
254. Decorin Promotes Differentiation of Myoblasts into Myotubes That Express Slow MyHC In VitroLi, Y. / Li, J. / Tang, Y. / Xiao, X. / Huard, J. et al. | 2005
- 101
-
257. Ex Vivo Gene Therapy for Duchenne Muscular Dystrophy: Lentiviral and PhiC31 Integrase ApproachesQuenneville, S. P. / Chapdelaine, P. / Rousseau, J. l. / Calos, M. P. / Tremblay, J. P. et al. | 2005
- 101
-
258. Identification of Differentially Expressed Genes in Duchenne Muscular Dystropy Utilising RNAi Technology: Possible Targets for Gene TherapySeno, M. M. / Graham, I. R. / Laing, K. / Pohlschmidt, M. / Athanasopoulos, T. / Crompton, M. / Dickson, G. J. et al. | 2005
- 101
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256. An Ideal Therapeutic Agent for Duchenne Muscular Dystrophy Involving a Gutted Adenovirus Expressing Full-Length UtrophinDeol, J. R. / Gilbert, R. / Bourget, M. / Moon, J. S. / Nalbantoglu, J. / Karpati, G. et al. | 2005
- 102
-
261. Recombinant Adeno-Associated Viral (rAAV) Microdystrophin Vectors as Therapeutic Tools for Duchenne Muscular Dystrophy (DMD)Athanasopoulos, T. / Graham, I. / Foster, H. / Perez, N. / Vulin, A. / Hill, V. / Fabb, S. / Garcia, L. / Danos, O. / Dickson, G. et al. | 2005
- 102
-
259. Uterine Fibroids Gene Therapy: Adenovirus-Mediated Herpes Simplex Virus Thymidine Kinase/Ganciclovir Treatment Inhibits Growth of Human and Rat Leiomyoma CellsAl-Hendy, A. / Kamel, M. / Christman, G. / Salama, S. A. et al. | 2005
- 102
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260. A Database for Managing Neuromuscular Disease Data in the Province of QuebecLuc, C. / Jeremie, L. / Jack, P. et al. | 2005
- 103
-
262. Plasmid-Mediated Gene Transfer in mdx Mice Using Mini- and Micro-Dystrophin ConstructsLim, L. E. / Bertoni, C. / Rando, T. A. et al. | 2005
- 103
-
263. Characterization and Gene Transfer in Mesenchymal Stem Cells Derived from Human Umbilical Cord BloodLu, F. / Jiang, J. / Fujino, M. / Li, X. K. et al. | 2005
- 104
-
264. Cell Therapy of Ovarian Failure: Intraovarian Transplanted Granulosa Cells Successfully Engraft and Repopulate Growing FolliclesAl-Hendy, A. / Wang, H. Q. / Salama, S. A. et al. | 2005
- 104
-
265. Enhanced Plasmid-Mediated Dystrophin Expression in the mdx Mouse Model for Duchenne Muscular Dystrophy by a PhiC31 Integrase Plasmid SystemBertoni, C. / Jarrahian, S. / Wheeler, T. M. / Li, Y. / Olivares, E. C. / Calos, M. P. / Rando, T. A. et al. | 2005
- 105
-
266. Development of rAAV-Based Skeletal and Cardiac Muscle Regulatory Cassettes for Gene Therapy of Duchenne Muscular DystrophySalva, M. Z. / Himeda, C. L. / Tai, P. / Blankinship, M. J. / Gregorevic, P. / Allen, J. M. / Meuse, L. A. / Chamberlain, J. S. / Hauschka, S. D. et al. | 2005
- 105
-
Pharmacologically Regulated Regeneration of Functional Human Pancreatic IsletsKobinger, G. P. / Deng, S. / Louboutin, J. P. / Vatamaniuk, M. / Rivera, V. M. / Lian, M. M. / Markmann, J. F. / Clackson, T. / Raper, S. E. / Matschinsky, F. et al. | 2005
- 105
-
267. Inflammatory Killing of Normal Cells To Treat Metastatic TumorsSanchez-Perez, L. / Daniels, G. / Kottke, T. / Diaz, R. M. / Ahmed, A. / Thompson, J. / Chong, H. / Vile, R. et al. | 2005
- 106
-
270. Vaccination of Recurrent Glioma Patients with Tumor Lysate-Pulsed Dendritic Cells Elicits Immune Responses: Results of a Clinical Phase I/II TrialYamanaka, R. / Homma, J. / Takahashi, M. / Tanaka, R. et al. | 2005
- 106
-
269. Stimulation of the Immune System Using Gene Therapy Is an Effective Approach for Treating Brain Tumors in Mouse and Rat ModelsCurtin, J. F. / King, G. D. / Xiong, W. / Liu, C. / Lowenstein, P. / Castro, M. et al. | 2005
- 106
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268. Primary Mouse Marrow Stromal Cells Behave as Antigen-Presenting Cells in Syngeneic Immune ResponsesStagg, J. / Pommey, S. / Galipeau, J. et al. | 2005
- 107
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272. Induction of Anti-Tumoral Immune Response and IFN-Regulated Factors by Delivery of Control DNALi, S. / Wilkinson, M. / Xia, X. / David, M. / Xu, L. et al. | 2005
- 107
-
273. Effects of Pre-Existing Immunity on Gene Therapy Mediated by First Generation or High Capacity Adenoviral Vectors Expressing Flt3L in a Syngeneic Glioma ModelKing, G. D. / Curtin, J. F. / Xiong, W. / Liu, C. / Palmer, D. / Ng, P. / Lowenstein, P. R. / Castro, M. G. et al. | 2005
- 107
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271. Interactions between Replicating Virotherapy and Tumor Growth in the Presence of an Intact Immune SystemForshaw, M. / Cole, C. / Kottke, T. / Thompson, J. / Qiao, J. / Selby, P. / Melcher, A. / Vile, R. et al. | 2005
- 108
-
275. RTVP-1 Protein Stimulates Markers of Maturation in Mouse and Human Dendritic CellsWang, H. / Abdelfattah, E. M. / Tahir, S. A. / Yang, G. / Goltsov, A. / Tian, W. / Ren, C. / Timme, T. L. / Thompson, T. C. et al. | 2005
- 108
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274. Genetic Immunotherapy Targeted to Antigen Presenting Cells Using a CD40-Targeted Adenoviral VectorMody, D. A. / Smart, L. / Odaka, Y. / Li, X. L. / Yilmaz, C. E. / Pereboev, A. V. / Mathis, J. M. et al. | 2005
- 109
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276. Enhancement of Cytotoxic T-Lymphocyte Responses Against Carcinoembryonic antigen (CEA) Using Genetically Modified Dendritic Cells Expressing CEA and CD40 LigandChinnasamy, N. / Neuenfeldt, J. / Shaffer, J. / Chinnasamy, D. et al. | 2005
- 109
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277. Large-Scale Generation of Genetically Modified Human CD34+ Progenitor Cell-Derived Langerhans Cells Using a Closed Culture System Suitable for Clinical ImmunotherapyYuan, J. / Kendle, R. / Hodges, J. / Sadelain, M. / Young, J. W. / Riviere, I. et al. | 2005
- 110
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279. A Novel Functionalized Polymeric Formulation for use in Delivering Therapeutic Genes for the Treatment of Solid TumorsFewell, J. / Matar, M. / Rice, J. / Slobodkin, G. / Hovanes, B. / Anwer, K. et al. | 2005
- 110
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278. Induction of Anti-Tumor Activity with Dendritic Cells Loaded with Tumor Cell Lysates or Adenoviral Vector-Encoding Tumor-Associated AntigensJeong, J. G. / Lee, H. J. / Ahn, H. S. / Oh, S. M. / Ho, S. H. / Cho, H. / Kang, S. / Kim, J. M. / Kim, S. et al. | 2005
- 110
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280. Effect of Polysaccharides from Medicinal Herbs as Danger Signals: Implication for Regulating Immune ResponsesShu, C. C. / Wang, J. H. / Wang, S. J. / Wen, J. C. / Wei, W. C. / Yen, Y. F. / Cheng, K. Y. / Shyur, L. F. / Yang, N. S. et al. | 2005
- 111
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284. CD137L Gene Transfer Generates Effective and Long-Lasting Immunity in a Murine Plasmocytoma ModelKim, Y. / Strehl, J. W. / Gorschluter, M. / Ziske, C. / Mayr, C. / Schmidt-Wolf, I. G. et al. | 2005
- 111
-
282. Effects of Fas Ligand on Inflammation and Tumor Survival Are Dependent on Its Expression LevelsTagawa, M. / Wada, A. / O-Wang, J. / Kawamura, K. / Shimozato, O. / Tada, Y. / Takiguchi, Y. / Tatsumi, K. / Kuriyama, T. et al. | 2005
- 111
-
283. Suppression of Inflammatory Pathways Selectively Induced by Oncolytic Viruses Enhances Viral OncolysisFulci, G. / Breymann, L. M. / Fontana, E. J. / Gianni, D. / Wakimoto, H. / Weissleder, R. / Lee, R. / Liu, Q. / Chiocca, A. E. et al. | 2005
- 111
-
281. Evaluation of Plant Polysaccharides and Phyto-Compounds on Inflammation-Associated Tumorigenesis by Using Melanoma DNA Vaccine ModelWang, S. J. / Wang, J. H. / Wei, W. C. / Shu, C. C. / Shyur, L. F. / Yang, N. S. et al. | 2005
- 112
-
Induction of IFN-regulated factors and antitumoral surveillance by transfected placebo plasmid DNALi, S. / Wilkinson, M. / Xia, X. / David, M. / Xu, L. / Purkel-Sutton, A. / Bhardwaj, A. et al. | 2005
- 112
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286. Therapeutic Approach Using External Radiation and Suicide Gene Therapy Transduced by Chimeric Adenovirus Vector for Bladder CancerMatsumoto, K. / Okuno, N. / Teh, B. S. / Freund, C. T. / Zhu, J. X. / Vlachaki, M. T. / Davis, A. R. / Butler, B. E. / Lerner, S. P. et al. | 2005
- 112
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285. Anti-Tumor Immune Responses Following Neoadjuvant Immunotherapy with a Recombinant Adenovirus Expressing HSP72 to Rodent TumorsKrewet, J. A. / Chen, S. Y. / Shah, M. R. et al. | 2005
- 113
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287. mda-7: A Remedy for Oncogene Addiction in Breast Cancer?Chada, S. / Liu, Y. / Bocangel, D. / Zheng, M. / Ramesh, R. / Meyn, R. / Hunt, K. et al. | 2005
- 113
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289. Highly Inducible and Prostate Specific Oncolytic Adenovirus with E1A-AR ChimeraLi, Y. / Chen, C. L. / Johns, D. C. / Rodriguez, R. et al. | 2005
- 113
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288. A System for GMP Expansion and Transduction of Human T Cells with High Functionality Proven by Consistent Induction of GvHD in a Mouse Xenotransplant ModelBauer, G. / Walker, J. / Nervi, B. / Ritchey, J. / Hughes, J. / Eades, B. / Bonyhadi, M. / Nolta, J. / DiPersio, J. et al. | 2005
- 114
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290. Alpha-Tocopherol Succinate (VES) Enhances Ad-mda7-Mediated Killing of Ovarian Cancer CellsShanker, M. / Chada, S. / Ramesh, R. et al. | 2005
- 114
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291. Comparison of Anti-Tumor Effects between Transmembrane and Secretory Tumor Necrosis Factor-alpha In Vitro and In VivoShi, W. / Li, Q. / Li, Z. et al. | 2005
- 114
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292. Primary Chronic Lymphocytic Leukaemia Cells Are Resistant to the Oncolytic Effects of Attenuated Measles VirusBates, M. A. / Wickremasinghe, R. G. / Fielding, A. K. et al. | 2005
- 115
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293. Optimizing the Efficacy of Spliceosome-Mediated RNA Trans-Splicing (SMaRT™) for Suicide Gene Therapy of Cervical CancerPatrick, M. / Puttaraju, M. / DiPasquale, J. / Quintero, J. / Yang, Y. / Garcia-Blanco, M. A. / Mitchell, L. G. / Otto, E. / Baker, C. C. et al. | 2005
- 115
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294. Adenoviral-TRAIL and a Smac34-8K Fusion Peptide Act Synergistically to Induce Apoptosis in Low CAR-Expressing Human Glioma CellsMushiake, H. / Hitchens, M. R. / Mai, J. C. / Seol, D. W. / Robbins, P. D. et al. | 2005
- 116
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295. Adeno-Associated Virus-Mediated Transfer of the Genes Encoding Cryptic Kringle Fragments of Apolipoprotein (A) Suppresses Tumor Growth and Metastasis In VivoLee, K. / Yun, S. T. / Jo, E. C. et al. | 2005
- 116
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297. Radiovirotherapy in Ovarian Cancer Using Recombinant Measles Expressing Sodium Iodide SymporterHasegawa, K. / Ong, H. T. / Dingli, D. / Nakamura, T. / Russell, S. J. / Peng, K. W. et al. | 2005
- 116
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298. Gene Therapy Against Prostate Cancer Using the HSV-tk/Prodrug System Followed by ProstatectomyRojas-Martinez, A. / Aguilar, L. K. / Ortiz-Lopez, R. / Esteban-Maria, J. / Gonzalez-Guerrero, J. F. / Garza-Guajardo, R. / Flores-Gutierrez, J. P. / Butler, E. B. / Barrera-Saldana, H. A. / Aguilar-Cordova, E. et al. | 2005
- 116
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296. Effective Suppression of Breast Cancer by Downregulation of VEGF SignalingLu, Y. / Zhang, J. / Beech, D. J. / Jennings, L. K. et al. | 2005
- 117
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299. Increasing Gene Transfer and Oncolytic Potency of Adenoviruses in Orthotopic Models of Gastric CancerKangasniemi, L. / Kanerva, A. / Raki, M. / Ranki, T. / Sarkioja, M. / Kiviluoto, T. / Stenman, U. H. / Alfthan, H. / Wu, H. / Curiel, D. T. et al. | 2005
- 117
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300. Adenoviral Delivery of the Gene Encoding Secretable Trimeric TRAIL Induces Apoptosis and Suppresses Human Malignant Glioma In VivoJeong, M. / Kwon, I. H. / Kim, C. Y. / Seol, D. W. / Robbins, P. D. / Kim, B. M. et al. | 2005
- 117
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301. Down-Regulation of bcl-xl Gene Expression with bcl-xl siRNA Vectors In Vitro and In VivoCao, X. X. / Rascoe, P. / Daniel, J. / Rodarte, C. / Smythe, W. R. et al. | 2005
- 118
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302. Herpes Simplex Virus Thymidine Kinase/Ganciclovir Therapy Mediated by Transferrin-Associated Lipoplexes in a Murine Model for Oral CancerNeves, S. S. / Simões, S. / Pedroso de Lima, M. C. et al. | 2005
- 118
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304. Gene Therapy of Malignant Brain Tumor by a Novel Double-Stranded Adeno-Associated Viral (AAV) Vector Carrying the Decorin GeneWang, C. H. / Master, J. M. / Chen, K. Y. / Cheng, S. Y. / Xiao, X. / Ma, H. I. et al. | 2005
- 118
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303. Validating CD46 as a Possible Mechanism Contributing to MV-Edm Oncolytic SpecificityOng, H. T. / Russell, S. J. / Peng, K. W. et al. | 2005
- 119
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305. A Safe TRAIL to Lung Tumor SpecificityShi, J. / Zheng, D. / Liu, Y. / Sham, M. H. / Tam, P. / Farzaneh, F. / Xu, R. et al. | 2005
- 119
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307. The Tumor-Selective Viral Protein Apoptin Is a Potential Gene Therapeutic Agent for Prostate Cancer TherapyLiu, X. / El-Zawhry, A. / Holman, D. / Elojeimy, S. / Bielawaska, A. / Bielawaska, J. / Tavassoli, M. / Norris, J. S. et al. | 2005
- 119
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306. A Novel Thymidine Kinase in Enhanced Gap Junction Mediated Suicide Gene TherapyEkstrom, T. J. / Khan, Z. / Gojkovic, Z. / Willer, M. / Almqvist, P. M. et al. | 2005
- 120
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310. Discovered Peptide Mediates Specific Binding to Primary Medullary Thyroid Carcinoma after Systemic InjectionBockmann, M. / Hilken, G. / Cranston, A. N. / Drosten, M. / Ponder, B. A. / Schmidt, A. / Putzer, B. M. et al. | 2005
- 120
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IL-2/B7.1 (CD80) Fusagene Transduction of AML Blasts by a Self-Inactivating Lentiviral Vector Stimulates T Cell Responses in Vitro: a Strategy to Generate Whole Cell Vaccines for AMLChan, L. / Hardwick, N. / Darling, D. / Galea-Lauri, J. / Gäken, J. / Devereux, S. / Kemeny, M. / Mufti, G. / Farzaneh, F. et al. | 2005
- 120
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308. In Vivo Enhancement of HSV-TK/GCV Cancer Gene Therapy with Polyamine Biosynthesis InhibitionWahlfors, T. / Karppinen, A. / Jänne, J. / Alhonen, L. / Wahlfors, J. et al. | 2005
- 120
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309. STAT5 Phosphorylation in Malignant Melanoma Is Mediated through SRC and JAK-1 Kinases and Exerts Anti-Apoptotic EffectsMirmohammadsadegh, A. / Bardenheuer, W. / Hassan, M. / Gustrau, A. / Selimovic, D. / Doroudi, R. / Schmittner, N. / Nambiar, S. / Marini, A. / Ruzicka, T. et al. | 2005
- 121
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311. Oncolytic Adenovirus CG5757 Preferentially Infects Primary Human Tumor Tissues and Shows Strong Anti-Tumor Activity in Tumor Models Following Systemic AdministrationLi, Y. / Arroyo, T. / Thorne, S. / Reid, T. / Nguyen, N. / Idamakanti, N. / VanRoey, M. / Colbern, G. / Yu, D. C. et al. | 2005
- 121
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312. Human Plasminogen Kringle 5-Engineered Murine Mammary Cancer Cells Arrest Tumor Growth and Promote Long-Term SurvivalPerri, S. R. / François, M. r. / Galipeau, J. et al. | 2005
- 122
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313. Efficacy of Group I Intron-Based Trans-Splicing Ribozyme in Tumor-Targeted Gene TherapyKwon, B. S. / Kim, J. H. / Jeong, J. S. / Kim, I. H. / Lee, S. W. et al. | 2005
- 122
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314. The Epithelial Glycoprotein-2 Promoter for Highly Specific and Efficient Cancer Gene Therapy for a Broad Range of TumorsGommans, W. M. / Duns, G. / McLaughlin, P. M. / van Eert, S. J. / Yamamoto, M. / Curiel, D. T. / Haisma, H. J. / Rots, M. G. et al. | 2005
- 123
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317. Raf-1 siRNA Inhibits Tumor Growth In VivoLeng, Q. / Mixson, A. J. et al. | 2005
- 123
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316. Dendritic Cell-Based Genetic Immunotherapy for Prostate CancerWilliams, B. J. / Korokhov, N. / Boling, S. / Li, L. / Mathis, M. / Curiel, D. T. et al. | 2005
- 123
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315. Highly Specific Expression of the Luciferase Gene in Lungs of Naïve Nude Mice Directed by Prostate Specific Antigen PromoterLi, H. / Li, J. Z. / Helm, G. A. / Pan, D. et al. | 2005
- 124
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319. ColoAd1, a Chimeric Ad11p/Ad3 Oncolytic Virus for the Treatment of Colon CancerKuhn, I. / Harden, P. / Bauzon, M. / Hermiston, T. et al. | 2005
- 124
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320. Antitumor Effect of Intrahepatic Interleukin-12 Expression from a Regulable Plasmid Vector in Murine Models of Primary and Metastatic Liver CancerZabala, M. / Hernandez-Alcoceba, R. / Ecay, M. / Melero, I. / Perret, C. / Penuelas, I. / Prieto, J. / Kramer, G. M. et al. | 2005
- 124
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318. Tumor Growth Inhibition from Tumor Targeted Delivery of Diphtheria Toxin GeneScaria, P. V. / Zhou, Q. / Schiffelers, R. M. / Ansari, A. / Woodle, M. C. et al. | 2005
- 125
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324. TRAIL Gene Therapy Is a Promising Therapy for Bladder CancerEl-Zawahry, A. M. / Voelkel-Johnson, C. et al. | 2005
- 125
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322. Tumor Specific Activation of Irinotecan by a Carboxylesterase Fused with Anti CEA scFvUchino, J. / Takayama, k. / Sone, T. / Harada, a. / Harada, T. / Curiel, D. T. / Nakanishi, Y. et al. | 2005
- 125
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323. Transcriptional Targeting of Viral Gene Transfer by Human Hexokinase II PromoterMaatta, A. M. / Korja, S. / Hakkarainen, T. / Wahlfors, J. / Mäkinen, K. / Alhava, E. / Pellinen, R. et al. | 2005
- 125
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321. Splice-Switching of the Prostate Specific Membrane Antigen (PSMA) in LnCap Prostate Cancer CellsWilliams, T. L. / Kole, R. et al. | 2005
- 126
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325. Identification of Genes Expressed Specifically in Esophageal Cancer CellsSati, F. / Abraham, J. M. / Yin, J. / Kan, T. / Mori, Y. / Meltzer, S. J. et al. | 2005
- 126
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326. Gene Therapeutic Overexpression of MDR1 Affects Transcriptional Regulations of Proteins Involved in Apoptosis and DetoxificationMaier, P. / Li, L. / Fleckenstein, K. / Laufs, S. / Fruehauf, S. / Zeller, J. / Wenz, F. / Herskind, C. et al. | 2005
- 127
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329. Use of Recombinant Non-Pathogenic Bacteria as Vectors for Hypoxia Targeted Gene Expression for Cancer Gene TherapyMengesha, A. / Dobois, L. / Wouters, B. G. / Lambin, P. / Theys, J. et al. | 2005
- 127
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327. The Effect of NO on HIF-Mediated Gene Expression: Chemical Sources of NO Versus Genetic Regulation of iNOSAl-Assah, R. S. / Cowen, R. L. / Chinje, E. C. / Stratford, I. J. et al. | 2005
- 127
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328. An Orthotopic Murine Model of Advanced Breast Cancer for Imaging and Comparison of Targeting MoietiesRanki, T. / Kanerva, A. / von Smitten, K. / Sarkioja, M. / Kangasniemi, L. / Raki, M. / Laakkonen, P. / Wu, H. / Curiel, D. T. / Goodison, S. et al. | 2005
- 128
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330. Lentiviral Vector Mediated Hematopoietic Stem Cell Gene Therapy Combined with Non-Lethal Conditioning Restores T Cell Function in the Murine Model of Wiskott-Aldrich SyndromeMarangoni, F. / Dupré, L. c. / Scaramuzza, S. / Trifari, S. / Hernández, R. J. / Thrasher, A. / Galy, A. / Aiuti, A. / Naldini, L. / Roncarolo, M. G. et al. | 2005
- 128
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331. Lentivirus-Mediated Ex Vivo Gene Therapy in ADA-Deficient SCID MiceMortellaro, A. / Hernández, R. J. / Guerrini, M. / Tabucchi, A. / Carlucci, F. / Follenzi, A. / Naldini, L. / Bordignon, C. / Roncarolo, M. G. / Aiuti, A. et al. | 2005
- 129
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333. Preferential Targeting of Transcriptional Start Sites after Retroviral-Mediated T-Cell Gene Therapy for Adenosine Deaminase DeficiencyMoratto, D. / Jagadeesh, J. G. / Konno, A. / Bosticardo, M. / Crawford, G. E. / Holt, I. / Muul, L. M. / Shurman, S. H. / Wolfsberg, T. / Candotti, F. et al. | 2005
- 129
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332. Chronic Granulomatous Disease Gene Therapy Functionally Corrects the Phenotype of Polymorphonuclear Leukocytes (PMN)Siler, U. / Ott, M. G. / Stein, S. / Karaus, E. / Rutishauser, M. / Wenk, C. / Hoelzer, D. / Grez, M. / Seger, R. et al. | 2005
- 129
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334. Treatment of Anemia in Mice with Chronic Renal Failure Utilizing Erythropoietin-Secreting Genetically-Engineered Murine Bone Marrow Stromal CellsEliopoulos, N. / Gagnon, R. F. / Francois, M. / Galipeau, J. et al. | 2005
- 130
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336. Correction of Chronic Granulomatous Disease by Gene TherapyGrez, M. / Ott, M. G. / Stein, S. / Siler, U. / Koehl, U. / Kunkel, H. / Schilz, A. / Kuehlcke, K. / Hoelzer, D. / Seger, R. et al. | 2005
- 130
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335. Correction of a Murine Model of Von Willebrand Disease by Gene TransferPergolizzi, R. G. / Guang, J. / Chan, D. / Wagner, D. / Lenting, P. / Crystal, R. G. et al. | 2005
- 131
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338. Non-Viral Gene Transfer into Hematopoietic Cells of Artemis Deficient ScidA Mice Using the Sleeping BeautyTransposon SystemWilber, A. / Buckley, S. / Lakshmipathy, U. / Frandsen, J. / Cowan, M. J. / McIvor, R. S. et al. | 2005
- 131
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337. Towards Gene Correction Therapy for Wiskott-Aldrich Syndrome with Engineered Zinc Finger NucleasesZhang, L. / Urnov, F. D. / Miller, J. C. / Beausejour, C. / Lee, Y. L. / Rock, J. / Kim, K. / Holmes, M. C. / Gregory, P. D. et al. | 2005
- 132
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339. Long-Term Protein Transduction Domain Mediated Intra-Cellular Delivery of Purine Nucleoside Phosphorylase (PNP) Corrects PNP Deficiency in MiceToro, A. / Grunebaum, E. et al. | 2005
- 132
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Genetically engineered dopamine β-hydroxylase gene promoters with better PHOX2-binding sites drive significantly enhanced transgene expression in a noradrenergic cell-specific mannerHwang, D. Y. / Hwang, M. M. / Kim, H. S. / Kim, K. S. et al. | 2005
- 132
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340. Drug-Selectable as Well as Therapeutic Gene Transfer into Hematopoietic Stem Cells May Be Essential in Gene Therapy for Inherited Bleeding Disorders of Large AnimalsWilcox, D. A. / Fang, J. / Du, L. M. / Boudreaux, M. K. et al. | 2005
- 133
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342. Human Erythropoietin Gene Therapy for Patients with Chronic Renal FailureLippin, Y. / Dranitzki-Elhale, M. / Brill-Almon, E. / Mei–Zahav, C. / Mizrachi, S. / Liberman, Y. / Iaina, A. / Kaplan, E. / Podjarny, E. / Casadevall, N. et al. | 2005
- 133
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343. Repair of Thalassemic β-Globin pre-mRNA by Antisense AAV and Lentiviral Vectors in Cell CultureSuwanmanee, T. / Choi, V. W. / Samulski, R. J. / Kafri, T. / Kole, R. et al. | 2005
- 133
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341. Lentiviral Vector-Mediated Gene Therapy as Treatment for Wiskott-Aldrich Syndrome (WAS): Pre-Clinical Studies in Human Cell Lines and WASp -/- MiceHumblet-Baron, S. / Anover, S. / Kipp, K. / Zhu, Q. / Ye, P. / Zhang, W. / Ovechkina, Y. / Khim, S. / Astrakhan, A. / Strom, T. et al. | 2005
- 134
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344. Application of a suicide Gene to X-SCID Gene TherapyUchiyama, T. / Kumaki, S. / Onodera, M. / Wei, D. / Yeng, L. C. / Sasahara, Y. / Tsuchiya, S. et al. | 2005
- 134
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345. Gene Therapy for Wiskott-Aldrich Syndrome Using Lentiviral Vectors: Evidence for Efficacy and Safety after Transduction of Human T Cells and Hematopoietic Stem CellsDupré, L. c. / Scaramuzza, S. / Marangoni, F. / Trifari, S. / Martino, S. / Tsuchiya, S. / Thrasher, A. / Galy, A. / Naldini, L. / Aiuti, A. et al. | 2005
- 135
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346. Gene Correction of X-Linked SCID Using Engineered Zinc Finger Nucleases and Integration Defective Lentiviral DeliveryLombardo, A. / Beausejour, C. / Urnov, F. D. / Miller, J. C. / Holmes, M. C. / Gregory, P. D. / Naldini, L. et al. | 2005
- 135
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347. Long-Term Gene Expression and Phenotypic Correction of FANCC Deficient Lymphoblastoid Cells Using the Sleeping Beauty Transposon SystemWadman, S. A. / Clark, K. J. / Hackett, P. B. / McIvor, R. S. / Essner, J. J. et al. | 2005
- 136
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349. Partial Correction of IL-12 Receptor beta-1 (IL-12Rb1) Deficiency in Mice upon Transplantation of Retrovirally Transduced Hematopoietic Stem CellsBosticardo, M. / Scanga, C. / Novelli, F. / Casanova, J. L. / Candotti, F. et al. | 2005
- 136
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348. Integration Site Analysis of a Helper-Dependent Adenovirus Vector Containing AAV ITRs and 22 kb of the Human Globin LCRWang, H. / Leege, T. / Shayakhmetov, D. / Li, Q. / Papayannopoulou, T. / Stamatoyannopolous, G. / Lieber, A. et al. | 2005
- 137
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351. Repeat Administration of Polyethylenimine (PEI) Aerosols of Plasmid DNA to the Murine Lung Is Associated with a Loss of Gene Transfer EfficiencyDavies, L. A. / Hyde, S. C. / Gill, D. R. et al. | 2005
- 137
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350. Pre-Clinical Assays for Cystic Fibrosis Gene TherapyGriesenbach, U. et al. | 2005
- 137
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352. Gene Transfer of Angiogenic Inhibitors Suppresses Lung Tumor Growth in Spontaneous Pulmonary Metastasis Mouse ModelCai, K. / Sham, M. H. / Xiao, W. / Tam, P. / Xu, R. et al. | 2005
- 138
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354. Correction of Respiratory Function by Recombinant AAV1 Mediated Gene Therapy in a Murine Model of Glycogen Storage Disease Type IIMah, C. / Cresawn, K. O. / DeRuisseau, L. R. / Fuller, D. / Byrne, B. J. et al. | 2005
- 138
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353. Retrovirally-Marked Human Bone Marrow Derived Mesenchymal Stem Cells Attenuate Radiation Induced Pneumonitis in a Xenotransplant ModelHope, A. / Meyerrose, T. E. / Nolta, J. A. et al. | 2005
- 139
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357. IL-17 Induces Migration of Adult Marrow Stromal Cells to Lung EpitheliumLoi, R. / Jaskolka, J. / Prenovitz, R. / Jian You, Y. / Brody, S. / Weiss, D. J. et al. | 2005
- 139
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356. Sonoporation Increases Non-Viral Gene Transfer to the Murine LungXenariou, S. / Liang, H. / Griesenbach, U. / Farley, R. / Somerton, L. / Singh, C. / So, P. W. / Herlihy, A. / Ferrari, S. / Geddes, D. et al. | 2005
- 139
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355. Towards Cystic Fibrosis and Airway Gene Therapy: Evaluation of EGFP Gene Expression in Murine Nasal Airways Mediated by Simian Immunodeficiency Virus Vectors Pseudotyped with Sendai Virus Glycoproteins F and HNMitomo, K. / Inoue, M. / Ueda, Y. / Ikegami, M. / Griesenbach, U. / Alton, E. W. / Hasegawa, M. et al. | 2005
- 140
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358. Gene Transfer to the Airway Epithelium Mediated by a Third Generation HIV-1 Based Vector: Efficiency and Role of Heparan SulfateCopreni, E. / Castellani, S. / Palmieri, L. / Carrabino, S. / Naldini, L. / Conese, M. et al. | 2005
- 140
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359. Specific Modulation of Tight Junctions to Enhance Airway Gene TransferEverett, R. S. / Vanhook, M. K. / Johnson, L. G. et al. | 2005
- 141
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361. Radiation-Induced Lung Apoptosis Is Mediated by TNF-alpha ActionZhang, M. / Qian, J. / Chen, M. / Kong, S. / Lawrence, T. S. et al. | 2005
- 141
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360. Disturbance of Airway Epithelium Is Reduced, Whilst Lentivirus-Mediated Gene Transfer Is Maintained, after Low Dose Lysophosphatidylcholine Pre-Treatment In VivoCmielewski, P. / Stocker, A. G. / Parsons, D. W. / Anson, D. S. et al. | 2005
- 141
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362. Using Real-Time (TaqMan®) PCR to Genotype Offspring of Transgenic CF-null Mice — A Core Facility of the UK Cystic Fibrosis Gene Therapy ConsortiumSmith, R. L. / Davies, L. A. / Painter, H. / Varathalingam, A. / Gill, D. R. / Hyde, S. C. et al. | 2005
- 142
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Development of Ecdysone-Regulated Lentiviral VectorsGalimi, F. / Saez, E. / Gall, J. / Hoong, N. / Cho, G. / Evans, R. M. / Verma, I. M. et al. | 2005
- 142
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363. Gene Delivery to Human Sweat Glands: A Model for Cystic Fibrosis Gene TherapyLee, H. / Koehler, D. R. / Pang, C. Y. / Levine, R. H. / Ng, P. / Palmer, D. J. / Quinton, P. M. / Hu, J. et al. | 2005
- 142
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364. Prevention of Radiation Pneumonitis by Recombinant Adenovirus-Mediated Transfer of Soluble TGF-βtype II Receptor GeneTakayama, K. / Zhang, H. / Uchino, J. / Harada, A. / Harada, T. / Nakanishi, Y. et al. | 2005
- 142
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366. Development of Quantitative TaqMan RT-PCR for the Evaluation of Non-Viral Mediated Gene Transfer to the AirwaysPringle, I. A. / Smith, R. L. / Jones, B. L. / Gill, D. R. / Hyde, S. C. et al. | 2005
- 142
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365. Aerosol Delivery of an Enhanced Helper-Dependent Adenovirus Formulation to Rabbit Lung Using an Intratracheal CatheterKoehler, D. R. / Frndova, H. / Leung, K. / Louca, E. / Palmer, D. / Ng, P. / McKerlie, C. / Cox, P. / Coates, A. L. / Hu, J. et al. | 2005
- 143
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367. Safety and Immunological Responses Following Intrapleural Administration of an AAV5 Vector Encoding Human α1-Antitrypsin to Non-Human PrimatesHarvey, B. G. / De, B. P. / Ayala, J. P. / Hackett, N. R. / Heguy, A. / Crystal, R. et al. | 2005
- 143
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368. Differential Sensitivity of Normal and CML-Derived CD34+Cells to Inhibition of SHP2, Gab2 and Stat5 Gene Expression by RNA Interference (RNAi)Scherr, M. / Battmer, K. / Chaturvedi, A. / Schultheis, B. / Ganser, A. / Eder, M. et al. | 2005
- 144
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369. Targeted Gene Modification Via Triple Helix-Forming OligonucleotidesGlazer, P. M. / Rogers, F. / Lloyd, J. et al. | 2005
- 144
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371. Optimizing Custom Zinc-Finger Nucleases for Use in Human CellsAlwin, S. / Gere, M. B. / Guhl, E. / Effertz, K. / Barbas, C. F. / Segal, D. J. / Weitzman, M. D. / Cathomen, T. et al. | 2005
- 144
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370. Multi-Copy, Multi-siRNA Vectors as Versatile Tools for Multiple Gene Knock-Down ApplicationsPoliseno, L. / Evangelista, M. / Giacca, M. / Rainaldi, G. et al. | 2005
- 145
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373. Use of Lentiviral and Adeno-Associated Vectors for Targeted Gene Inactivation in Human Cancer CellsArena, S. / Vigna, E. / Naldini, L. / Bardelli, A. et al. | 2005
- 145
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372. Targeting of Non-Viral Vectors to Specific Subnuclear DomainsGasiorowski, J. Z. / Dean, D. A. et al. | 2005
- 146
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376. Various Aspects of the Single-Stranded DNA Fragment-Mediated Gene CorrectionTsuchiya, H. / Harashima, H. / Kamiya, H. et al. | 2005
- 146
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377. Developing siRNAs to the E2Fs to Control Vascular Growth and RemodelingGiangrande, P. H. / Zhang, J. / Layzer, J. / Hagen, O. / Nevins, J. R. / Sullenger, B. A. et al. | 2005
- 146
-
375. Targeted Gene Repair Induces the DNA Damage Response Pathways through the Activation of ATM, and the Stalling of Replication Forks Leading to a Blockage of Inherited CorrectionFerrara, L. / Engstrom, J. / Brachman, E. / Drury, M. / Kmiec, E. B. et al. | 2005
- 146
-
374. Knockdown of Shp-2 Expression by siRNA in Mouse Embryonic Stem Cell Derived EB Cells Affects Their Hematopoietic DevelopmentZou, G. M. / Chan, R. J. / Shelley, W. C. / Yoder, M. C. et al. | 2005
- 147
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380. Studies on the Mechanism of Gene Repair Using Saccharomyces cerevisae as a Model SystemMaguire, K. / Parekh-Olmedo, H. / Kmiec, E. B. et al. | 2005
- 147
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378. Retargeting Mobile Group II Introns to Repair Mutant GenesKierlin, M. N. / Jones, J. P. / Coon, R. G. / Perutka, J. / Lambowitz, A. M. / Sullenger, B. A. et al. | 2005
- 147
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379. New Zinc Finger Protein Nuclease Architectures for More Efficient Gene Modification TherapiesMiller, J. C. / Zhang, L. / Urnov, F. D. / Patterson, S. / Xia, D. / Rock, J. / Augustus, S. / Pabo, C. O. / Gregory, P. D. / Rebar, E. J. et al. | 2005
- 148
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382. Expanding the Repertoire of Heterospecific LoxP Sites for Cre-Mediated Site-Specific RecombinationLanger, S. J. / Keith, J. / Leinwand, L. A. et al. | 2005
- 148
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381. Methods for Optimizing Lentiviral Vector-Mediated Gene Suppression by RNA InterferenceKizana, E. / Ramirez, G. / Cingolani, E. / Abraham, R. / Marban, E. et al. | 2005
- 148
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383. Zinc Finger Nuclease-Boosted Gene Targeting and Synergistic Transient Regenerative Stem Cell Gene Therapy: Toward Clinical Gene Repair/Alteration and Custom Site-Specific Integrative Gene TherapyBertolotti, R. et al. | 2005
- 149
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385. Gene Correction in the Absence of DNA Repair: A Universal Model Involving Homologous Pairing and DNA ReplicationParekh-Olmedo, H. / Brachman, E. / Kmiec, E. B. et al. | 2005
- 149
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Clinical and local biological effects of an intratumoral injection of mda-7 (IL24; INGN 241) in patients with advanced carcinoma: a phase I studyCunningham, C. C. / Chada, S. / Merritt, J. A. / Tong, A. / Senzer, N. / Zhang, Y. / Mhashilkar, A. / Parker, K. / Vukelja, S. / Richards, D. et al. | 2005
- 149
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384. Double-Stranded DNA Breaks Stimulate the Frequency of Targeted Gene Repair in Mammalian CellsSchwartz, T. / Ferrara, L. / Parekh-Olmedo, H. / Kmiec, E. B. et al. | 2005
- 149
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386. Large Scale Analysis of Foamy Virus Vector Integration Sites in Human CD34+ CellsTrobridge, G. / Miller, D. G. / Jacobs, M. A. / Allen, J. M. / Olson, E. / Kiem, H. P. / Kaul, R. / Russell, D. W. et al. | 2005
- 150
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389. Testing the Oncogenic Potential of Retroviral and Lentiviral Vector IntegrationMontini, E. / Cesana, D. / Sanvito, F. / Lucia, S. S. / Fabrizio, B. / Maurilio, P. / Doglioni, C. / Naldini, L. et al. | 2005
- 150
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387. Myeloid Sarcoma Associated with Gene Marking of Hematopoietic Stem Cells in a Rhesus MacaqueSeggewiss, R. / Pittaluga, S. / Adler, R. / Ferguson, C. / Vanin, E. F. / Kelly, P. F. / Donahue, R. E. / Sorrentino, B. P. / Nienhuis, A. W. / Dunbar, C. E. et al. | 2005
- 150
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388. Use of the cHS4 Chromatin Insulator to Reduce Oncoretrovirus Vector-Mediated GenotoxicityEmery, D. W. / Li, C. / Stamatoyannopoulos, G. et al. | 2005
- 151
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390. Flanking a Retrovirus Vector with the cHS4 Chromatin Insulator Reduces the Frequency of Vector-Mediated Trans-Activation of Endogenous GenesLi, C. / Emery, D. W. et al. | 2005
- 151
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391. Effective Gene Therapy with Non-Integrating Lentivirus VectorsYáñez-Muñoz, R. J. / Balaggan, K. S. / MacNeil, A. / Smith, A. J. / Buch, P. / Howe, S. / Durán, Y. / MacLaren, R. E. / Anderson, P. N. / Kinnon, C. et al. | 2005
- 152
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392. Development of a New Lentiviral Vector for Site-Specific Integration into Mammalian GenomesLombardo, A. / Calos, M. / Naldini, L. et al. | 2005
- 152
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393. Site-Directed Integration in Human Genome by Lentiviral Vectors Containing HIV-1 Integrase/Polydactyl Zinc Finger Fusion ProteinsTan, W. / Dong, Z. / Luo, V. / Chow, S. A. et al. | 2005
- 152
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394. Oncogenesis Following Delivery of a Non-Primate Lentiviral Gene Therapy Vector to Fetal MiceThemis, M. / Waddington, S. N. / Schmidt, M. / von Kalle, C. / Wang, Y. / Al-Allaf, F. / Gregory, L. / Nivsarkar, M. / Holder, M. et al. | 2005
- 153
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396. Identification and Characterization of Novel AAV IsolatesSchmidt, M. K. / Grott, E. / Buck, C. / Chiorini, J. A. et al. | 2005
- 153
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395. Safety of In Utero Gene Delivery of Lentiviral VectorsKingsman, S. M. / Miskin, J. E. / Radcliffe, P. A. / Hacker, C. V. / Chipchase, D. / Mazarakis, N. D. / Mitrophanous, K. A. et al. | 2005
- 153
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397. AAV-Mediated Gene Transfer to Endothelial CellsHsieh, M. Y. / Liu, Y. L. / Schlachterman, A. / High, K. A. et al. | 2005
- 154
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398. Adeno-Associated Virus Serotype 8 Efficiently Crosses Blood Vessel Barrier in Muscle and Heart for Whole-Body - DeliveryWang, Z. / Zhu, T. / Qiao, C. / Zhou, L. / Wang, B. / Zhang, J. / Chen, C. / Li, J. / Xiao, X. et al. | 2005
- 154
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399. rAAV2 Movement Through the Late and Recycling Endosomes Is Influenced by Titer of InfectionZhang, L. / Ding, W. / Engelhardt, J. F. et al. | 2005
- 155
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400. Successful Production of Pseudotyped Mosaic rAAV Vectors Using a Modified Baculovirus Expression SystemKohlbrenner, E. / Aslanidi, G. / Nash, K. / Shklayev, S. / Campbell-Thompson, M. / Byrne, B. J. / Snyder, R. O. / Muzyczka, N. / Warrington, K. H. / Zolotukhin, S. et al. | 2005
- 155
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402. Comparison of Pseudotyped rAAV Vectors for Transduction of Primary Hematopoietic Stem and Progenitor Cells Assayed In Vitro and In VivoLi, L. / Hardy, S. / Smith-Powell, L. / Srinivas, S. / Forman, S. J. / Wong, K. K. / Chatterjee, S. et al. | 2005
- 155
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401. Evaluation of Primitive Murine Hematopoietic Stem and Progenitor Cell Transduction In Vitro and In Vivo by Recombinant Adeno-Associated Virus Vectors Based on Serotypes 1 through 5Zhong, L. / Li, W. / Li, Y. / Qing, K. / Yoder, M. C. / Srivastava, A. et al. | 2005
- 156
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404. Roles of Inverted Terminal Repeats (ITRs) and Capsid Proteins from Novel NHP AAVs in rAAV Mediated Gene TransferZhou, X. / Gao, G. / Owens, R. A. / Lu, Y. / Calcedo, R. / Miller, J. / Wilson, J. M. et al. | 2005
- 156
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403. Defined Vector Substrates Used To Probe rAAV DNA IntegrationMcCarty, D. M. / Choi, V. / Fernandes, A. / Samulski, R. J. et al. | 2005
- 157
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405. Comparison Study of Structural Determinants for AAV Liver Transduction by Domain Swapping between AAV-2 and AAV-8 CapsidsShen, X. / Xu, H. / Huang, Z. / Storm, T. A. / Kay, M. A. et al. | 2005
- 157
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407. Complement Blockade Prevents Several Innate Toxicities Rapidly Induced after Intravenous Adenovirus (Ad) Vector AdministrationKiang, A. / Hartman, Z. / Wei, J. P. / Everett, R. / Serra, D. / Jiang, H. / Frank, M. M. / Amalfitano, A. et al. | 2005
- 157
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406. Role of MyD88 Signaling Pathway in the Host Immune Responses in Adenoviral Vector-Mediated Gene TherapyZhang, Z. / Gao, G. P. / Wetzler, L. M. / Zhi, Y. / Wilson, J. M. et al. | 2005
- 158
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409. Identifying Functional Adenovirus-Host Interactions Using Tandem Mass SpectrometryGaggar, A. / Sadilek, M. / Lieber, A. / Shayakhmetov, D. M. et al. | 2005
- 158
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408. The Kupffer Cell Scavenger Receptor Is Accountable for Hepatic Sequestration of AdenovirusHaisma, H. J. / Bellu, A. R. / Rots, M. G. / Kamps, G. / Plantinga, J. / Kamps, J. et al. | 2005
- 159
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412. Renal Pathophysiology after Systemic Administration of a Recombinant Adenovirus: Changes in Drug Metabolism Based upon Vector DoseBoquet, M. P. / Le, H. T. / Clark, E. A. / Callahan, S. M. / Croyle, M. A. et al. | 2005
- 159
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410. Adenovirus Activates Mouse Platelets and Induces Platelet Leucocyte AssociationOthman, M. / Labelle, A. / Lillicrap, D. et al. | 2005
- 159
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411. Trapping of Adenovirus Vectors in BloodStone, D. / Ni, S. / Li, Z. Y. / Shayakhmetov, D. M. / Lieber, A. et al. | 2005
- 160
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414. Vitamin B2: A Key Component for Controlled Inactivation of Viruses Suitable for Biological UseCallahan, S. M. / Wonganan, P. / Obenauer-Kutner, L. J. / Sutjipto, S. / Le, H. T. / Croyle, M. A. et al. | 2005
- 160
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Intratumoral Injection of INGN 241, a Nonreplicating Adenovector Expressing the Melanoma-Differentiation Associated Gene-7 (mda-7/IL24): Biologic Outcome in Advanced Cancer PatientsTong, A. W. / Nemunaitis, J. / Su, D. / Zhang, Y. / Cunningham, C. / Senzer, N. / Netto, G. / Rich, D. / Mhashilkar, A. / Parker, K. et al. | 2005
- 160
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413. Functional Differences of the Reticuloendothelial System in C57BL/6 and Balb/c Mice Mediate Differential Effects of Kuppfer Cell Blockade, Rag-Deficiency and Splenectomy on Transgene Expression after Adenoviral TransferSnoeys, J. / Mertens, G. / Lievens, J. / Collen, D. s. / Biessen, E. / De Geest, B. et al. | 2005
- 161
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416. Glucose-Dependent Insulin Production by Liver-Specific, Glucose-Regulatable Synthetic Promoters Results in the Cure of DiabetesHan, J. / McLane, B. / Jun, H. S. / Yoon, J. W. et al. | 2005
- 161
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415. Evaluating Polyethylene Glycol (PEG) Modified Adenoviral Vectors for Cell Targeting and Detargeting and Reducing Vector ToxicityMok, H. / Barry, M. A. et al. | 2005
- 162
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418. rAAV-Mediated Expression of Adiponectin Receptor (AdipoR2) cDNA in Muscle Prevents the Development of Obesity in DIO RatsAslanidi, G. / Shklayev, S. / Kohlbrenner, E. / Kroutov, V. / Walter, G. / Campbell-Thompson, M. / Zolotukhin, S. et al. | 2005
- 162
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419. Generation of Transgene Product-Specific Regulatory CD4+CD25+ T Cells by Hepatic AAV Gene TransferCao, O. / Dobrzynski, E. / Mingle, B. L. / Wang, L. / Herzog, R. W. et al. | 2005
- 162
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417. Meganuclease-Mediated Chromosomal Surgery in Living AnimalsGouble, A. / Smith, J. / Perez, C. / Guyot, V. / Cabaniols, J. P. / Leduc, S. / Fiette, L. / Ave, P. / Micheaux, B. / Duchateau, P. et al. | 2005
- 163
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420. Tropism-Modified Adeno-Associated Virus Vector Mediates Targeting of Brain Vascular Endothelium In VivoChen, Y. H. / Davidson, B. L. et al. | 2005
- 163
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421. Liver Contains Sufficient Sulfatase Modifying Factor for 4-Sulfatase and Correction of MPS VI with Neonatal Retroviral Gene Therapy in CatsHaskins, M. / O'Malley, T. / Wang, B. / Metgcalf, J. / Wang, P. / Hopwood, J. / Ponder, K. P. et al. | 2005
- 163
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422. Dominant-Negative Interference in the Pahenu2 Mouse Model of PKU: Effectiveness of Vectors Expressing Either Modified Forms of Phenylalanine Hydroxylase (PAH) or Ribozymes Plus a Hardened PAH mRNACharron, C. E. / Perera, O. P. / Porvasnik, S. L. / Blackburn, M. / Lewin, A. S. / Laipis, P. J. et al. | 2005
- 164
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423. Increased Incidence of Hepatocellular Change and Neoplastic Disease in AAV-WPRE Treated Pahenu2 MiceEmbury, J. E. / Charron, C. E. / Laipis, P. J. et al. | 2005
- 164
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424. Intracranial AAV5 Synergizes with Non-Myeloablative Bone Marrow Transplantation in the Murine Model of Globoid-Cell LeukodystrophyLin, D. / Donsante, A. / Macauley, S. / Levy, B. / Vogler, C. / Sands, M. et al. | 2005
- 165
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425. AAV2-Mediated Expression of Iduronate Sulfatase in Peripheral Tissues and the CNS in Mucopolysaccharidosis II Mouse Model by Combined Intravenous and Intracisternal Vector DeliveryKang, L. / Fu, H. / Jennings, J. S. / Muenzer, J. et al. | 2005
- 165
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426. Cure of Established Disease and Direct Evidence of Cellular Cross-Correction in the Nervous System of Metachromatic Leukodystrophy Mice after HSC-Based Gene TherapyBiffi, A. / Capotondo, A. / Quattrini, A. / Del Carro, U. / Brambilla, R. / Fasano, S. / Marchesini, S. / Bordignon, C. / Naldini, L. et al. | 2005
- 166
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429. AAV5-Mediated Delivery of Human Aryl Sulfatase A (hARSA) Prevents Sufatide Storage and Neuropathological Phenotype in Metachromatic Leukodystrophy (MLD) MiceCartier, N. / Sevin, C. / Benraiss, A. / DeDeyn, P. / Bonnin, D. / Vanier, M. T. / Philippe, M. / Gieselmann, V. / Aubourg, P. et al. | 2005
- 166
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427. AAV2- and AAV5-Mediated CNS Delivery of Human CLN2 Reduces Lysosomal Storage in a Mouse Model of Late Infantile Neuronal Ceroid LipofuscinosisPassini, M. A. / Sondhi, D. / Dodge, J. C. / Bu, J. / Yang, W. / Hackett, N. R. / Kaminsky, S. M. / El-Banna, M. / Mao, Q. / Davidson, B. L. et al. | 2005
- 166
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428. A Novel Approach for the Treatment of the Neurological Symptoms of MPS VII (Sly Disease)Spencer, B. J. / Verma, I. M. et al. | 2005
- 167
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432. Molecular Chimerism Prevents Experimental Autoimmune Encephalomyelitis (EAE)Eixarch, H. / Espejo, C. / Vidal, F. / Garces, S. / Castillo, M. / Bote, A. / Kadar, E. / Rosal, M. / Montalban, X. / Barquinero, J. et al. | 2005
- 167
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430. Immune System Regulation of Transgene Expression from High-Capacity Gutless Adenoviral Vectors in the Mouse Brain: Very Long Term Expression Following Pre-ImmunizationBarcia, C. / Zirger, J. M. / Xiong, W. / Ng, P. / Palmer, D. / Castro, M. G. / Lowenstein, P. R. et al. | 2005
- 167
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431. In Utero CNS Delivery of an Integrating HSV-1 Amplicon Vector Leads to Prolonged, Neuron-Specific Gene ExpressionBowers, W. J. / Mastrangelo, M. A. / Casey, A. E. / Southerland, H. A. / Maguire-Zeiss, K. A. / Federoff, H. J. et al. | 2005
- 168
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434. Long-Term Effects on Retinal Function and Structure Using AAV-Mediated Gene Therapy in Blind RPE65 Null Mutation DogsNarfstrom, K. / Tullis, G. / Bragadottir, R. / Seeliger, M. / Rakoczy, E. P. / Katz, M. L. et al. | 2005
- 168
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433. Gene Therapy of Epilepsy by Adenovirus-Mediated Tetanus Toxin Light Chain Gene TransferYang, J. / Teng, Q. / Garrity-Moses, M. E. / Federici, T. / Najm, I. / Chabardes, S. / Moffitt, M. / Boulis, N. M. et al. | 2005
- 169
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435. Functional and Morphological Rescue of the Type I Ocular Albinism Murine Retina Following AAV-Mediated Gene TransferSurace, E. M. / Domenici, L. / Cortese, K. / Venturi, C. / Cotugno, G. / Di Vicino, U. / Cellerino, A. / Marigo, V. / Tacchetti, C. / Ballabio, A. et al. | 2005
- 169
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437. Alternative Strategies To Deliver Multiple shRNAs in Order to Simultaneously Inhibit Multiple TargetsRoelvink, P. W. / Graham, M. W. / Suhy, D. A. / Couto, L. B. / Cunningham, S. M. / Kay, M. A. / Rossi, J. J. / Kolykhalov, A. A. et al. | 2005
- 169
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436. shRNAs Target HIV-1 Vif Gene Coding for SOCS-Box Motif Prevent Virus Escape from RNA Interference-Mediated InhibitionJi, J. / Rossi, J. J. et al. | 2005
- 170
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439. CXCR4 and CCR5 shRNA Transgenic Macrophages Are Functionally Normal and Resist HIV-1 InfectionAnderson, J. / Akkina, R. et al. | 2005
- 170
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438. Development of an siRNA Based Therapy for Hepatitis Virus InfectionMorrissey, D. V. / Blanchard, K. / Shaw, L. / Jensen, K. / Breen, W. / Zinnen, S. / Dickinson, B. / McSwiggen, J. A. / Vargeese, C. / Bowman, K. et al. | 2005
- 170
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440. A Non-Human Primate Model for Lentivirus-Mediated Anti-HIV RNAi StrategiesBeagles, K. / Trobridge, G. / Beard, B. / Rossi, J. / Yee, J. K. / Hu, S. L. / KIem, H. P. et al. | 2005
- 171
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442. Evaluation of siRNA for Induction of In Vitro Resistance in HIV-1Yam, P. / Wu, J. / Yu, Y. / Zaia, J. A. / Yee, J. K. et al. | 2005
- 171
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443. Tissue Specific Expression of Short Hairpin RNAs for the Treatment of HCV Using Liver Specific RNA Pol II Expression CassettesSuhy, D. A. / Kolykhalov, A. A. / Couto, L. B. / Garcia, L. M. / Schroeder, A. R. / Parker, A. E. / Haniff, G. / Cunningham, S. M. / Kay, M. A. / Roelvink, P. W. et al. | 2005
- 171
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441. Short Hairpin RNA Interference Expressed from a Gene-Deleted Adenoviral Vector Results in Reduction of Hepatits B Surface Antigen Levels In Vitro and in a Small Animal Model for Hepatitis B InfectionEhrhardt, A. / Xu, H. / Salazar, F. H. / Marion, P. L. / Kay, M. A. et al. | 2005
- 172
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444. A New Vector Which Targets Breast Cancer and Its VasculatureLiu, Y. / Ye, T. / Maynard, J. / Akbulut, H. / Deisseroth, A. et al. | 2005
- 172
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445. Combinatorial Antiangiogenic Gene Therapy by Nonviral Gene Transfer Using the Sleeping Beauty Transposon Causes Tumor Regression and Improves Survival in Mice Bearing Intracranial Human GlioblastomaOhlfest, J. R. / Demorest, Z. L. / Motooka, Y. / Vengco, I. / Oh, S. / Chen, E. / Scappaticci, F. A. / Ekker, S. C. / Low, W. C. / Freese, A. B. et al. | 2005
- 173
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The NIH roadmap: timing is everythingWilliams, D. A. et al. | 2005
- 173
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447. Mesenchymal Stem Cells as Delivery Systems for Cancer Therapy: Evaluation of Tropism and EfficacyMarini, F. / Dembinski, J. / Studeny, M. / Zompetta, C. / Andreeff, M. et al. | 2005
- 173
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448. A Genetic Strategy to Inhibit Complement Activation Arising from Adenoviral VectorsZinn, K. R. / Wu, H. / Stargel, A. / Adams, A. J. / Chaudhuri, T. R. et al. | 2005
- 173
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446. Tie2 Expression Defines an Integrated System of Cell Types Specifically Involved in Angiogenesis, and Provides a Platform for Targeted Gene Delivery to TumorsDe Palma, M. / Venneri, M. A. / Galli, R. / Belmonte, N. / Sampaolesi, M. / Sergi Sergi, L. / Naldini, L. et al. | 2005
- 174
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Inside this month| 2005
- 174
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449. Tumor Targeted, Systemic Delivery of Therapeutic Viral Vectors Using Hitch Hiking on Antigen Specific T CellsQiao, J. / Cole, C. / Kottke, T. / Diaz, R. M. / Sanchez-Perez, L. / Brunn, G. / Thompson, J. / Vile, R. et al. | 2005
- 174
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450. Combination of Fas Gene Therapy and Ceramide Analogues: A Double Edge Sword for the Treatment of Head and Neck CancerElojeimy, S. N. / McKillop, J. C. / El-Zawahry, A. M. / Schwartz, D. A. / Holman, D. H. / Liu, X. / Day, T. / Bielawska, A. / Hannun, Y. A. / Norris, J. S. et al. | 2005
- 175
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451. Matrix Metalloproteinase-Targeted Oncolytic Sendai Virus Vector “Armed? with a Sucide Gene “Yeast Cytosine Deaminase?; Remarkable Combinational EffectsKinoh, H. / Inoue, M. / Washizawa, K. / Akiba, E. / Hasegawa, M. et al. | 2005
- 175
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453. The Histone Deacetylase Inhibitor FK228 Can Increase Adenovirus Transgene Protein Expression in Human LOX IMVI Melanoma XenograftsGoldsmith, M. E. / Aguila, A. / Alley, M. C. / Waud, W. R. / Bates, S. / Fojo, T. et al. | 2005
- 175
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452. The Enhancement of Anticancer Effect of Chemotherapy by the Delivery of Rad51 siRNAIto, M. / Yamamoto, S. / Nimura, K. / Tamai, K. / Kaneda, Y. et al. | 2005
- 175
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Research update| 2005
- 176
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455. Drug Resistance Gene Therapy to Induce Donor-Specific Tolerance after Nonmyeloablative Allogeneic Stem Cell Transplantation in DogsGerull, S. / Beagles, K. E. / C. Beard, B. / Peterson, L. J. / Kiem, H. P. et al. | 2005
- 176
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454. Mouse Models for the Analysis of Genetic Risk Factors for Hematopoietic Transformation in XSCID Gene TherapyShou, Y. / Stepanova, L. / Sorrentino, B. P. et al. | 2005
- 177
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The need for antidoping researchCawley, A. et al. | 2005
- 177
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457. The Benefits of CH-296 during Ex Vivo Gene Transfer Go beyond the Ability to Co-Localize the Retroviral Particle and Target CellDao, M. A. / Nolta, J. A. et al. | 2005
- 177
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458. Reversal of Canine Leukocyte Adhesion Deficiency by Retroviral-Vector Mediated Gene Therapy with Non-Myeloablative ConditioningBauer, T. R. / Tuschong, L. M. / Hai, M. / Gu, Y. c. / Sokolic, R. A. / Burkholder, T. / Bacher, J. D. / Hickstein, D. D. et al. | 2005
- 177
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456. HOXB4 Overexpression Expands Short-Term Repopulating Cells in Nonhuman Primates and DogsZhang, X. B. / Peterson, L. J. / Knapp, A. A. / Beard, B. C. / Humphries, R. K. / Kiem, H. P. et al. | 2005
- 178
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The Twelfth Annual Meeting of the European Society of Gene TherapyGrez, M. / Galun, E. / Moullier, P. et al. | 2005
- 178
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460. Transplantation of Human Aldehyde Dehydrogenase Expressing Cells Leads to Widespread Tissue Distribution of Donor Cells in the Pancreas and Liver of NOD/SCID/MPSVII MiceHess, D. A. / Craft, T. P. / Wirthlin, L. / Herrbrich, P. E. / Hofling, A. A. / Sands, M. S. / Nolta, J. A. et al. | 2005
- 178
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459. Long-Term Treatment of Canine Cyclic Neutropenia by G-CSF-LentivirusOsborne, W. / Brzezinski, M. / Yanay, O. / Waldon, L. / Christensen, J. / Liggitt, D. / Dale, D. et al. | 2005
- 179
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462. Busulfan Dose Escalation to Increase Gene Marking of Hematopoietic Stem Cells by Lentiviral Vectors in Infant Rhesus MonkeysKahl, C. A. / Tarantal, A. F. / Lee, C. I. / Jimenez, D. F. / Choi, C. / Pepper, K. / Peterson, D. / Fletcher, M. D. / Leapley, A. C. / Kohn, D. B. et al. | 2005
- 179
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463. Efficient Lentiviral Gene Transfer and Expression in Human Embryonic Stem CellsLutzko, C. / Yu, X. / Senadheera, D. / Kohn, D. B. et al. | 2005
- 179
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461. Qualitative and Quantitative Luciferase Expression In Vivo of Transduced Hematopoietic Cell Populations Using Bioluminescent Imaging (BLI)Rozemuller, H. / Koggel, I. F. / Spaapen, R. / Hagenbeek, A. / Martens, A. C. et al. | 2005
- 180
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466. Long-Term Rapamycin Control of Transgene Expression in Mouse Salivary Glands in a Single AAV VectorWang, J. / Voutetakis, A. / Papa, M. / Rivera, V. M. / Clackson, T. / Lodde, B. M. / Mineshiba, F. / Baum, B. J. et al. | 2005
- 180
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464. Development of a Novel Gene Regulation System Downstream of PromoterDuan, H. / Li, C. / Samulski, R. J. et al. | 2005
- 180
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Fighting Cancer with Vaccinia Virus: Teaching New Tricks to an Old DogShen, Y. / Nemunaitis, J. et al. | 2005
- 180
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465. In Vivo Selection of Genetically Modified Primary Human Hematopoietic Cells Using a Cell Growth SwitchWang, L. / Nagasawa, Y. / Wood, B. / Lintmaer, I. / Papayannopoulou, T. / Harkey, M. / Nougirat, C. / Blau, C. A. et al. | 2005
- 181
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468. Cellular Therapy with Transgene Expressing APC Activates CD4 + CD25+ Regulatory T Cells Which Modulate the Immune Response to Gene Therapy Derived Products in Immunocompetent MiceAnnoni, A. / Battaglia, M. / Follenzi, A. / Lombardo, A. / Naldini, L. / Grazia Roncarolo, M. et al. | 2005
- 181
-
467. Allogeneic Bone-Marrow Transplantation in Mice Provides Tolerance and Promotes Massive In Vivo Selection of Subsequently Transplanted HepatocytesStreetz, K. L. / Doyonnas, R. / Jenkins, D. D. / Lin, S. / Shizuru, J. A. / Blau, H. / Sylvester, K. / Kay, M. A. et al. | 2005
- 182
-
469. Induction of Donor Specific Tolerance Using Gene Therapy and Sublethal ConditioningForman, D. / Tian, C. / Iacomini, J. et al. | 2005
- 182
-
470. Foamy Viral Mediated Transduction of Recombinant FANCC in the Absence of Prestimulation Is Sufficient To Restore the Long Term Repopulating Activity of Fancc -/- Stem Cells and Prevent the Acquisition of Myeloid MalignanciesSi, Y. / Leurs, C. / Srour, E. F. / Yuan, J. / Hanenberg, H. / Clapp, D. W. et al. | 2005
- 183
-
473. Definitive Identification and Isolation of Embryonic Stem Cell-Derived Target Cells by Adenoviral Conditional Targeting; Efficient Purification of Immature and Mature Cells in the Cardiac LineageKosai, K. i. / Takahashi, T. et al. | 2005
- 183
-
472. Hematopoietic Cell Differentiation from Common Marmoset (Callithrix jacchus) Embryonic Stem Cells by Their Genetic Manipulation Using the Third Generation Lentiviral VectorYokoo, T. / Kurita, R. / Sasaki, E. / Hiroyama, T. / Nakazaki, Y. / Izawa, K. / Ishii, H. / Tanioka, Y. / Hanazawa, K. / Son Bai, Y. et al. | 2005
- 183
-
471. Microvessel Injury and Irradiation Damage in Salivary GlandsCotrim, A. P. / Wang, J. / Voutetakis, A. / Sowers, A. L. / Mitchell, J. B. / Baum, B. J. et al. | 2005
- 184
-
475. In Vivo Targeting of MLV(HIV) Pseudotype Vectors to T Lymphocytes in a Transgenic Mouse ModelSchuele, S. / Steidl, S. / Raupp, S. / Coulibaly, C. / Kalinke, U. / Cichutek, K. / Schweizer, M. et al. | 2005
- 184
-
474. Transduction of Minimally Stimulated Hematopoietic Progenitor Cells with a Foamy Virus Vector That Expresses MGMTP140KCai, S. / Hartwell, J. R. / Ernstberger, A. G. / Goebel, W. S. / Hanenberg, H. / Pollok, K. E. et al. | 2005
- 185
-
476. HIV-1 and HIV-2 Chimeric Lentiviral Vectors for Gene TransferSachdeva, G. / Kachapati, K. / Arya, S. et al. | 2005
- 185
-
477. Development of SIV Based Vectors with Efficient Delivery for Vector Dynamic Studies in the Simian SystemChen, C. / Lu, J. / Slepushkina, T. / Worden, A. / Slepushkin, V. / Humeau, L. M. / Binder, G. K. / Lu, X. et al. | 2005