Design, synthesis and bioevaluation of novel candidate selective estrogen receptor modulators (Englisch)
- Neue Suche nach: Yadav, Y.
- Neue Suche nach: MacLean, E. D.
- Neue Suche nach: Bhattacharyya, A.
- Neue Suche nach: Parmar, V. S.
- Neue Suche nach: Balzarini, J.
- Neue Suche nach: Barden, C. J.
- Neue Suche nach: Too, C. K.
- Neue Suche nach: Jha, A.
- Neue Suche nach: Yadav, Y.
- Neue Suche nach: MacLean, E. D.
- Neue Suche nach: Bhattacharyya, A.
- Neue Suche nach: Parmar, V. S.
- Neue Suche nach: Balzarini, J.
- Neue Suche nach: Barden, C. J.
- Neue Suche nach: Too, C. K.
- Neue Suche nach: Jha, A.
In:
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
;
46
, 9
;
3858-3866
;
2011
-
ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:Design, synthesis and bioevaluation of novel candidate selective estrogen receptor modulators
-
Beteiligte:Yadav, Y. ( Autor:in ) / MacLean, E. D. ( Autor:in ) / Bhattacharyya, A. ( Autor:in ) / Parmar, V. S. ( Autor:in ) / Balzarini, J. ( Autor:in ) / Barden, C. J. ( Autor:in ) / Too, C. K. ( Autor:in ) / Jha, A. ( Autor:in )
-
Erschienen in:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ; 46, 9 ; 3858-3866
-
Verlag:
- Neue Suche nach: Elsevier Science B.V., Amsterdam.
-
Erscheinungsdatum:01.01.2011
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Format / Umfang:9 pages
-
ISSN:
-
Medientyp:Aufsatz (Zeitschrift)
-
Format:Print
-
Sprache:Englisch
- Neue Suche nach: 615.1
- Weitere Informationen zu Dewey Decimal Classification
-
Klassifikation:
DDC: 615.1 -
Datenquelle:
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Synthesis and biological evaluation of novel Mannich bases of 2-arylimidazo[2,1-b]benzothiazoles as potential anti-cancer agentsKumbhare, R. M. / Vijay Kumar, K. / Janaki Ramaiah, M. / Dadmal, T. / Pushpavalli, S. N. / Mukhopadhyay, D. / Divya, B. / Anjana Devi, T. / Kosurkar, U. / Pal-Bhadra, M. et al. | 2011
- 4267
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Synthesis and in vitro antibacterial activity of a series of novel gatifloxacin derivativesChai, Y. / Liu, M. L. / Lv, K. / Feng, L. S. / Li, S. J. / Sun, L. Y. / Wang, S. / Guo, H. Y. et al. | 2011
- 4274
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Virtual lock-and-key approach: The in silico revival of Fischer model by means of molecular descriptorsLauria, A. / Tutone, M. / Almerico, A. M. et al. | 2011
- 4281
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Acyclic nucleoside thiophosphonates as potent inhibitors of HIV and HBV replicationBarral, K. / Weck, C. / Payrot, N. / Roux, L. / Durafour, C. / Zoulim, F. / Neyts, J. / Balzarini, J. / Canard, B. / Priet, S. et al. | 2011
- 4289
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The selective P-TEFb inhibitor CAN508 targets angiogenesisKrystof, V. / Rarova, L. / Liebl, J. / Zahler, S. / Jorda, R. / Voller, J. / Cankar, P. et al. | 2011
- 4295
-
Synthesis, evaluation against Leishmania amazonensis and cytotoxicity assays in macrophages of sixteen new congeners Morita-Baylis-Hillman adductsSilva, F. P. / de Assis, P. A. / Junior, C. G. / de Andrade, N. G. / da Cunha, S. M. / Oliveira, M. R. / Vasconcellos, M. L. et al. | 2011
- 4302
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Novel aryloxy azolyl chalcones with potent activity against Mycobacterium tuberculosis H37RvMarrapu, V. K. / Chaturvedi, V. / Singh, S. / Sinha, S. / Bhandari, K. et al. | 2011
- 4311
-
Imidazo[2,1-b]thiazole guanylhydrazones as RSK2 inhibitors [1]Andreani, A. / Granaiola, M. / Leoni, A. / Locatelli, A. / Morigi, R. / Rambaldi, M. / Varoli, L. / Lannigan, D. / Smith, J. / Scudiero, D. et al. | 2011
- 4324
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Synthesis and biological evaluation of some novel cyclic-imides as hypoglycaemic, anti-hyperlipidemic agentsAbdel-Aziz, A. A. / El-Azab, A. S. / Attia, S. M. / Al-Obaid, A. M. / Al-Omar, M. A. / El-Subbagh, H. I. et al. | 2011
- 4330
-
Refinement of arylthiosemicarbazone pharmacophore in inhibition of mushroom tyrosinaseYi, W. / Dubois, C. / Yahiaoui, S. / Haudecoeur, R. / Belle, C. / Song, H. / Hardre, R. / Reglier, M. / Boumendjel, A. et al. | 2011
- 4336
-
Multi-target strategy to address Alzheimer’s disease: Design, synthesis and biological evaluation of new tacrine-based dimersRizzo, S. / Bisi, A. / Bartolini, M. / Mancini, F. / Belluti, F. / Gobbi, S. / Andrisano, V. / Rampa, A. et al. | 2011
- 4344
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Locating the binding sites of anticancer tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen on bovine serum albuminBourassa, P. / Dubeau, S. / Maharvi, G. M. / Fauq, A. H. / Thomas, T. J. / Tajmir-Riahi, H. A. et al. | 2011
- 4354
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Synthesis and studies of novel 2-(4-cyano-3-trifluoromethylphenyl amino)-4-(quinoline-4-yloxy)-6-(piperazinyl/piperidinyl)-s-triazines as potential antimicrobial, antimycobacterial and anticancer agentsPatel, R. V. / Kumari, P. / Rajani, D. P. / Chikhalia, K. H. et al. | 2011
- 4366
-
One-pot synthesis of pyrazoline derivatised carbazoles as antitubercular, anticancer agents, their DNA cleavage and antioxidant activitiesTaj, T. / Kamble, R. R. / Gireesh, T. M. / Hunnur, R. K. / Margankop, S. B. et al. | 2011
- 4374
-
Synthesis, antifungal activity and QSAR study of 2-arylhydroxynitroindolesKokurkina, G. V. / Dutov, M. D. / Shevelev, S. A. / Popkov, S. V. / Zakharov, A. V. / Poroikov, V. V. et al. | 2011
- 4383
-
Synthesis, crystal structures, and biological evaluation of manganese(II) and nickel(II) complexes of 4-cyclohexyl-1-(1-(pyrazin-2-yl)ethylidene)thiosemicarbazideLi, M. X. / Zhang, L. Z. / Zhang, D. / Ji, B. S. / Zhao, J. W. et al. | 2011
- 4391
-
Synthesis of novel fluconazoliums and their evaluation for antibacterial and antifungal activitiesZhang, Y. Y. / Mi, J. L. / Zhou, C. H. / Zhou, X. D. et al. | 2011
- 4403
-
Carbonic anhydrase inhibitors. Synthesis, molecular structures, and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with novel 3-pyridinesulfonamide derivativesBrzozowski, Z. / Slawinski, J. / Gdaniec, M. / Innocenti, A. / Supuran, C. T. et al. | 2011
- 4411
-
Synthesis and anticancer evaluation of novel 2-cyclopropylimidazo[2,1-b][1,3,4]-thiadiazole derivativesNoolvi, M. N. / Patel, H. M. / Singh, N. / Gadad, A. K. / Cameotra, S. S. / Badiger, A. et al. | 2011
- 4419
-
Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyaseBraun, S. / Botzki, A. / Salmen, S. / Textor, C. / Bernhardt, G. / Dove, S. / Buschauer, A. et al. | 2011
- 4430
-
Photodynamic efficacy of water-soluble Si(IV) and Ge(IV) phthalocyanines towards Candida albicans planktonic and biofilm culturesMantareva, V. / Angelov, I. / Kussovski, V. / Dimitrov, R. / Lapok, L. / Wohrle, D. et al. | 2011
- 4441
-
Effect of 4-aryl-2-methyl-5-nitro-1,4-dihydropyridine-3-carboxylates on the guinea pig papillary muscle and isolated human vena saphena magna that is used for coronary artery bypass graftingGaraliene, V. / Barsys, V. / Macys, A. / Vigante, B. / Krauze, A. et al. | 2011
- 4448
-
Quinolinyl and quinolinyl N-oxide chalcones: Synthesis, antifungal and cytotoxic activitiesde Carvalho Tavares, L. / Johann, S. / Maria de Almeida Alves, T. / Guerra, J. C. / Maria de Souza-Fagundes, E. / Cisalpino, P. S. / Bortoluzzi, A. J. / Caramori, G. F. / de Mattos Piccoli, R. / Braibante, H. T. et al. | 2011
- 4457
-
Photophysical properties of fluorescently-labeled peptoidsRudat, B. / Birtalan, E. / Vollrath, S. B. / Fritz, D. / Kolmel, D. K. / Nieger, M. / Schepers, U. / Mullen, K. / Eisler, H. J. / Lemmer, U. et al. | 2011
- 4466
-
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stabilityVacondio, F. / Silva, C. / Lodola, A. / Carmi, C. / Rivara, S. / Duranti, A. / Tontini, A. / Sanchini, S. / Clapper, J. R. / Piomelli, D. et al. | 2011
- 4474
-
Synthesis and biological investigation of potential atypical antipsychotics with a tropane core. Part 1Slowinski, T. / Stefanowicz, J. / Dawidowski, M. / Kleps, J. / Czuczwar, S. / Andres-Mach, M. / Luszczki, J. J. / Nowak, G. / Stachowicz, K. / Szewczyk, B. et al. | 2011
- 4489
-
Homology modeling in tandem with 3D-QSAR analyses: A computational approach to depict the agonist binding site of the human CB2 receptorCichero, E. / Ligresti, A. / Allara, M. / di Marzo, V. / Lazzati, Z. / D’ / Ursi, P. / Marabotti, A. / Milanesi, L. / Spallarossa, A. et al. | 2011
- 4506
-
Tertiary amides with a five-membered heteroaromatic ring as new probes for the translocator proteinCosimelli, B. / Simorini, F. / Taliani, S. / La Motta, C. / Da Settimo, F. / Severi, E. / Greco, G. / Novellino, E. / Costa, B. / Da Pozzo, E. et al. | 2011
- 4521
-
Quinonoid and phenazine compounds: Synthesis and evaluation against H37Rv, rifampicin and isoniazid-resistance strains of Mycobacterium tuberculosisCarneiro, P. F. / Pinto, M. d. / Coelho, T. S. / Cavalcanti, B. C. / Pessoa, C. / de Simone, C. A. / Nunes, I. K. / de Oliveira, N. M. / de Almeida, R. G. / Pinto, A. V. et al. | 2011
- 4530
-
A facile four-component sequential protocol in the expedient synthesis of novel 2-aryl-5-methyl-2,3-dihydro-1H-3-pyrazolones in water and their antitubercular evaluationGunasekaran, P. / Perumal, S. / Yogeeswari, P. / Sriram, D. et al. | 2011
- 4537
-
Cytotoxic copper (II) mixed ligand complexes: Crystal structure and DNA cleavage activityManikandamathavan, V. M. / Parameswari, R. P. / Weyhermuller, T. / Vasanthi, H. R. / Nair, B. U. et al. | 2011
- 4548
-
Comparative study on antioxidant capacity of flavonoids and their inhibitory effects on oleic acid-induced hepatic steatosis in vitroZhang, D. / Xie, L. / Jia, G. / Cai, S. / Ji, B. / Liu, Y. / Wu, W. / Zhou, F. / Wang, A. / Chu, L. et al. | 2011
- 4559
-
Stereospecific ligands and their complexes. Part VII. Synthesis, characterization and in vitro antitumoral activity of platinum(II) complexes with O,Oprime-dialkyl esters of (S,S)-ethylenediamine-N,Nprime-di-2-(4-methyl)pentanoic acidVujic, J. M. / Kaluderovic, G. N. / Milovanovic, M. / Zmejkovski, B. B. / Volarevic, V. / Zivic, D. / Durdevic, P. / Arsenijevic, N. / Trifunovic, S. R. et al. | 2011
- 4566
-
Design and synthesis of some new thiophene, thienopyrimidine and thienothiadiazine derivatives of antipyrine as potential antimicrobial agentsAly, H. M. / Saleh, N. M. / Elhady, H. A. et al. | 2011
- 4573
-
6-Substituted imidazo[1,2-a]pyridines: Synthesis and biological activity against colon cancer cell lines HT-29 and Caco-2Dahan-Farkas, N. / Langley, C. / Rousseau, A. L. / Yadav, D. B. / Davids, H. / de Koning, C. B. et al. | 2011
- 4584
-
Biological evaluation of a novel water soluble sulphur bridged binuclear copper(II) thiosemicarbazone complexSenthil Raja, D. / Bhuvanesh, N. S. / Natarajan, K. et al. | 2011
- 4595
-
Synthesis, biochemical and molecular modelling studies of antiproliferative azetidinones causing microtubule disruption and mitotic catastropheO’ / Boyle, N. M. / Carr, M. / Greene, L. M. / Keely, N. O. / Knox, A. J. / McCabe, T. / Lloyd, D. G. / Zisterer, D. M. / Meegan, M. J. et al. | 2011
- 4608
-
Cyclolinopeptide derivatives modify methotrexate-induced suppression of the humoral immune response in miceKatarzynska, J. / Mazur, A. / Rudzinska, E. / Artym, J. / Zimecki, M. / Jankowski, S. / Zabrocki, J. et al. | 2011
- 4618
-
Isoeugenol-based novel potent antioxidants: Synthesis and reactivityF&imath / nd&imath / k, E. / Ceylan, M. / Elmastas, M. et al. | 2011
- 4625
-
Synthesis, antimicrobial activity and possible mechanism of action of 9-bromo-substituted indolizinoquinoline-5,12-dione derivativesWu, X. W. / Wu, Z. P. / Wang, L. X. / Zhang, H. B. / Chen, J. W. / Zhang, W. / Gu, L. Q. / Huang, Z. S. / An, L. K. et al. | 2011
- 4634
-
Synthesis and anticonvulsant properties of new acetamide derivatives of phthalimide, and its saturated cyclohexane and norbornene analogsKaminski, K. / Obniska, J. / Wiklik, B. / Atamanyuk, D. et al. | 2011
- 4642
-
Synthesis of novel 6-phenyl-2,4-disubstituted pyrimidine-5-carbonitriles as potential antimicrobial agentsAl-Abdullah, E. S. / Al-Obaid, A. R. / Al-Deeb, O. A. / Habib, E. E. / El-Emam, A. A. et al. | 2011
- 4648
-
Discovery and kinetic evaluation of 6-substituted 4-benzylthio-1,3,5-triazin-2(1H)-ones as inhibitors of cathepsin BSosic, I. / Mirkovic, B. / Turk, S. / Stefane, B. / Kos, J. / Gobec, S. et al. | 2011
- 4657
-
A chrysin analog exhibited strong inhibitory activities against both PGE2 and NO productionChe, H. / Lim, H. / Kim, H. P. / Park, H. et al. | 2011
- 4661
-
Consensus virtual screening approaches to predict protein ligandsKukol, A. et al. | 2011
- 4665
-
Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer’s diseaseSamadi, A. / Chioua, M. / Bolea, I. / de los Rios, C. / Iriepa, I. / Moraleda, I. / Bastida, A. / Esteban, G. / Unzeta, M. / Galvez, E. et al. | 2011
- 4669
-
Synthesis, characterization and biological evaluation of novel 2,4,6-trisubstituted bis-pyrimidine derivativesParveen, H. / Hayat, F. / Mukhtar, S. / Salahuddin, A. / Khan, A. / Islam, F. / Azam, A. et al. | 2011
- 4676
-
Synthesis and pharmacological assessment of diversely substituted pyrazolo[3,4-b]quinoline, and benzo[b]pyrazolo[4,3-g][1,8]naphthyridine derivativesSilva, D. / Chioua, M. / Samadi, A. / Carmo Carreiras, M. / Jimeno, M. L. / Mendes, E. / Rios, C. d. / Romero, A. / Villarroya, M. / Lopez, M. G. et al. | 2011
- 4682
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Aminothiophenedicarboxamides and dicyanothiopheneacetamides as effective synthetic molluscicides against Indoplanorbis exustus snailKanawade, S. B. / Toche, R. B. / Patil, S. P. / Desai, A. E. / Bhamare, S. S. et al. | 2011
- 4687
-
Synthesis and In-vitro anti-inflammatory activity of novel glycodendrimers with benzene 1,3,5 carboxamide core and triazole as branching unitRajakumar, P. / Anandhan, R. et al. | 2011
- 4696
-
Synthesis, pharmacological evaluation and docking studies of coumarin derivativesSandhya, B. / Giles, D. / Mathew, V. / Basavarajaswamy, G. / Abraham, R. et al. | 2011
- 4702
-
Synthesis, molecular modeling and biological evaluation of chalcone thiosemicarbazide derivatives as novel anticancer agentsZhang, H. J. / Qian, Y. / Zhu, D. D. / Yang, X. G. / Zhu, H. L. et al. | 2011
- 4709
-
Synthesis of 4b-triazole-podophyllotoxin derivatives by azide-alkyne cycloaddition and biological evaluation as potential antitumor agentsChen, H. / Zuo, S. / Wang, X. / Tang, X. / Zhao, M. / Lu, Y. / Chen, L. / Liu, J. / Liu, Y. / Liu, D. et al. | 2011
- 4715
-
Antimicrobial activity of pyrimidinophanes with thiocytosine and uracil moietiesSemenov, V. E. / Mikhailov, A. S. / Voloshina, A. D. / Kulik, N. V. / Nikitashina, A. D. / Zobov, V. V. / Kharlamov, S. V. / Latypov, S. K. / Reznik, V. S. et al. | 2011
- 4725
-
Synthesis and screening of galactose-linked nitroimidazoles and triazoles against Mycobacterium tuberculosisMugunthan, G. / Ramakrishna, K. / Sriram, D. / Yogeeswari, P. / Ravindranathan Kartha, K. P. et al. | 2011
- 4733
-
Arylamides hybrids of two high-affinity 2 receptor ligands as tools for the development of PET radiotracersAbate, C. / Ferorelli, S. / Contino, M. / Marottoli, R. / Colabufo, N. A. / Perrone, R. / Berardi, F. et al. | 2011
- 4742
-
Novel terpene based 1,4,2-dioxazoles: Synthesis, characterization, molecular properties and screening against Entamoeba histolyticaYounus Wani, M. / Athar, F. / Salauddin, A. / Mohan Agarwal, S. / Azam, A. / Choi, I. / Roouf Bhat, A. et al. | 2011
- 4753
-
Synthesis, computational studies and preliminary pharmacological evaluation of 2-[4-(aryl substituted) piperazin-1-yl] N, N-diphenylacetamides as potential antipsychoticsKumar, S. / Wahi, A. K. / Singh, R. et al. | 2011
- 4760
-
Synthesis and preliminary in vitro biological evaluation of new carbon-11-labeled celecoxib derivatives as candidate PET tracers for imaging of COX-2 expression in cancerGao, M. / Wang, M. / Miller, K. D. / Zheng, Q. H. et al. | 2011
- iii
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Graphical contents list| 2011
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Editorial board| 2011