CD36 is not involved in alternative pathway-mediated complement-dependent cytotoxicity on proximal tubular epithelial cells (Englisch)
- Neue Suche nach: Kenawy, H. I.
- Neue Suche nach: Bevington, A.
- Neue Suche nach: Stover, C. M.
- Neue Suche nach: Ali, Y. M.
- Neue Suche nach: Shwaeble, W. J.
- Neue Suche nach: Brunskill, N. J.
- Neue Suche nach: Kenawy, H. I.
- Neue Suche nach: Bevington, A.
- Neue Suche nach: Stover, C. M.
- Neue Suche nach: Ali, Y. M.
- Neue Suche nach: Shwaeble, W. J.
- Neue Suche nach: Brunskill, N. J.
In:
IMMUNOBIOLOGY -STUTTGART-
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217
, 11
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1148
;
2012
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ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:CD36 is not involved in alternative pathway-mediated complement-dependent cytotoxicity on proximal tubular epithelial cells
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Beteiligte:Kenawy, H. I. ( Autor:in ) / Bevington, A. ( Autor:in ) / Stover, C. M. ( Autor:in ) / Ali, Y. M. ( Autor:in ) / Shwaeble, W. J. ( Autor:in ) / Brunskill, N. J. ( Autor:in )
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Erschienen in:IMMUNOBIOLOGY -STUTTGART- ; 217, 11 ; 1148
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Verlag:
- Neue Suche nach: Elsevier Science B. V., Amsterdam
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Erscheinungsdatum:01.01.2012
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Format / Umfang:1148 pages
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ISSN:
-
Medientyp:Aufsatz (Zeitschrift)
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Format:Print
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Sprache:Englisch
- Neue Suche nach: 571.96
- Weitere Informationen zu Dewey Decimal Classification
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Klassifikation:
DDC: 571.96 -
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PrefaceLambris, J. D. / Hajishengallis, G. / Ricklin, D. et al. | 2012
- 1026
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The complement system in ischemia-reperfusion injuriesGorsuch, W. B. / Chrysanthou, E. / Schwaeble, W. J. / Stahl, G. L. et al. | 2012
- 1034
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Complement dysregulation and disease: From genes and proteins to diagnostics and drugsde Cordoba, S. R. / Tortajada, A. / Harris, C. L. / Morgan, B. P. et al. | 2012
- 1047
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Bride and groom in systemic inflammation - The bells ring for complement and Toll in cooperationBarratt-Due, A. / Pischke, S. E. / Brekke, O. L. / Thorgersen, E. B. / Nielsen, E. W. / Espevik, T. / Huber-Lang, M. / Mollnes, T. E. et al. | 2012
- 1057
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Manipulating the mediator: Modulation of the alternative complement pathway C3 convertase in health, disease and therapyRicklin, D. et al. | 2012
- 1067
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The immunoglobulin, IgG Fc receptor and complement triangle in autoimmune diseasesKarsten, C. M. / Kohl, J. et al. | 2012
- 1080
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Paroxysmal nocturnal hemoglobinuria and other complement-mediated hematological disordersRisitano, A. M. et al. | 2012
- 1088
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Interactions of the complement system with molecules of extracellular matrix: Relevance for joint diseasesHapponen, K. E. / Heinegard, D. / Saxne, T. / Blom, A. M. et al. | 2012
- 1097
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Targeted complement inhibition as a promising strategy for preventing inflammatory complications in hemodialysisDeAngelis, R. A. / Reis, E. S. / Ricklin, D. / Lambris, J. D. et al. | 2012
- 1106
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The tick-over theory revisited: Is C3 a contact-activated protein?Nilsson, B. / Nilsson Ekdahl, K. et al. | 2012
- 1111
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Complement and dysbiosis in periodontal diseaseHajishengallis, G. / Lambris, J. D. et al. | 2012
- 1117
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Putting the structure into complementLea, S. M. / Johnson, S. et al. | 2012
- 1122
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Interactions of the humoral pattern recognition molecule PTX3 with the complement systemDoni, A. / Garlanda, C. / Bottazzi, B. / Meri, S. / Garred, P. / Mantovani, A. et al. | 2012
- 1129
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Galactosylated IgG1 immune complexes diminish C5a-dependent inflammation in experimental Epidermolysis Bullosa AcquisitaKilchenstein, R. / Figge, J. / Karsten, C. M. / Brown, G. D. / Ludwig, R. / Zillikens, D. / Kohl, J. et al. | 2012
- 1129
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The systemic inflammatory reaction in polymicrobial sepsis induced by murine cecal ligation and puncture is equally dependent on C5 and CD14Mollnes, T. E. / Barratt-Due, A. / Pischke, S. E. / Sandanger, O. / Nunn, M. A. / Espevik, T. / Denk, S. / Huber-Lang, M. et al. | 2012
- 1130
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The lectin pathway triggered by activated plateletsKozarcanin, H. / Ekdahl, K. N. / Nilsson, B. et al. | 2012
- 1130
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A new FH autoantibody-induced murine aHUS model reveals a major protective role of decay-accelerating factor in the pathogenesis of ahus due to FH dysfunctionMiwa, T. / Sato, S. / Tung, K. S. / Song, W. C. et al. | 2012
- 1130
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A possible role of MAP-1 in skeletal muscle regenerationMunthe-Fog, L. / Schjerling, P. / Skjoedt, M. O. / Krag, T. / Madsen, H. O. / Vissing, J. / Kjaer, M. / Garred, P. et al. | 2012
- 1131
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A novel assay to quantitate MASP-2/ficolin-3 complexes in serumCsuka, D. / Munthe-Fog, L. / Skjoedt, M. O. / Hein, E. / Bay, J. T. / Varga, L. / Fust, G. / Garred, P. et al. | 2012
- 1131
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A novel factor H-FC chimeric immunotherapeutic molecule against Neisseria gonorrhoeaeShaughnessy, J. / Gulati, S. / Monks, B. G. / Visintin, A. / Ram, S. / Rice, P. A. et al. | 2012
- 1131
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A novel hybrid CFHR2/CFHR5 gene develops MPGN II and provides insights into disease mechanism and therapeutic implicationsChen, Q. / Wiesener, M. / Eberhardt, H. / Hartmann, A. / Hugo, C. / Skerka, C. / Zipfel, P. F. et al. | 2012
- 1132
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A novel non-coding mutation in C1q that causes C1q deficiency associated with recurrent infectionsTrouw, L. / Schonkeren, J. / Daha, N. / Levarht, N. / Roos, A. / Ernst-Kruis, M. / Huizinga, T. / Lankester, A. / Toes, R. et al. | 2012
- 1132
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A novel method for detection of eculizumab in complex with C5: Application in serum from a pregnant patient and her newborn childBergseth, G. / Hallstensen, R. F. / Jaeger, S. / Christiansen, D. / Holt, J. / Mollnes, T. E. et al. | 2012
- 1133
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A rapid and reliable method to detect homozygous CFHR1 deletion and its association with anti-factor H antibodies in atypical hemolytic uremic syndromeValoti, E. / Iatropoulos, P. / Sorosina, A. / Alberti, M. / Bresin, E. / Donadelli, R. / Noris, M. et al. | 2012
- 1133
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A role for C1q in normal brain agingStephan, A. H. / Madison, D. V. / Mateos, J. M. / Fraser, D. / Coutellier, L. / Lovelett, E. / Tsai, H. H. / Huang, E. / Rowitch, D. / Kim, L. et al. | 2012
- 1133
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A novel role for C5a as a regulator of B1 cell biologyFigge, J. / Karsten, C. M. / Kohl, J. et al. | 2012
- 1134
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A study of 46 atypical HUS mutations reveals that C3 and factor H mutations mirror each other on protein surfaces, engaged in the C3b-FH complexRoumenina, L. T. / Rybkine, T. / Mignotet, M. / Hyvarinen, S. / Hue, C. / Noris, M. / Jokiranta, S. / Dragon-Durey, M. A. / Halbwachs-Mecarelli, L. / Fremeaux-Bacchi, V. et al. | 2012
- 1134
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A user-friendly method to study the effect of FH and impact of FB variants on C3bBb convertase and C3bB proconvertase formationBettoni, S. / Donadelli, R. / Roumenina, L. / Fremeaux-Bacchi, V. / Noris, M. et al. | 2012
- 1134
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Abnormal factor H/FHRS proteins in sera from aHUS patients reveal novel CFH/CFHRS gene rearrangements of potential pathological relevanceAlba-Dominguez, M. / Martinez-Barricarte, R. / Pinto, S. / Abarrategui-Garrido, C. / Lopez-Trascasa, M. / de Cordoba, S. R. / Sanchez-Corral, P. et al. | 2012
- 1135
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Achieving efficient systemic delivery of oncolytic Vaccinia virusEvgin, L. / Lemay, C. / Falls, T. / Ilkow, C. / Breitbach, C. / Kirn, D. / Atkins, H. / Bell, J. et al. | 2012
- 1135
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Activation of the lectin pathway of complement in pig to human xenotransplantation: Role of natural IgMBongoni, A. K. / Rieben, R. et al. | 2012
- 1135
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Activation of the classical complement pathway in lung cancer: A novel biomarker for diagnosis and prognosisAjona, D. / Pajares, M. J. / Corrales, L. / Montuenga, L. M. / Pio, R. et al. | 2012
- 1136
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Amyloid beta (AB) as a local regulator of complement activation?Veerhuis, R. / Koel-Simmelink, M. J. et al. | 2012
- 1136
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AFFITOPE-based vaccination against C5a alleviates disease progression in a mouse model of Alzheimer's diseaseLandlinger, C. / Oberleitner, L. / Gruber, P. / Mandler, M. / Mattner, F. / Staffler, G. et al. | 2012
- 1136
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Allogeneic bone marrow transplantation restores complement function in human hereditary C1q deficiencyOlsson, R. / Hagelberg, S. / Ringden, O. / Truedsson, L. / Ahlin, A. et al. | 2012
- 1137
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An engineered construct combining complement regulatory and surface recognition domains as a minimal-size functional factor HHebecker, M. / Strobel, S. / Jozsi, M. et al. | 2012
- 1137
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An ex vivo posttreatment model of sepsis: Effect on inflammation by adding complement- and CD14-inhibitors after E. coli to human whole bloodEgge, K. H. / Thorgersen, E. B. / Lindstad, J. K. / Pharo, A. M. / Barratt-Due, A. / Mollnes, T. E. et al. | 2012
- 1137
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An alternative role of C1q in bacterial infections: Facilitating Streptococcus pneumoniae adherence and invasion of host cellsAgarwal, V. / Ahl, J. / Riesbeck, K. / Blom, A. M. et al. | 2012
- 1138
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Analysis of genes coding for CD46, CD55 and C4b-binding protein in patients with idiopathic, recurrent, spontaneous pregnancy lossMohlin, F. C. / Mercier, E. / Fremeaux-Bacchi, V. / Liszewski, M. K. / Atkinson, J. P. / Gris, J. C. / Blom, A. M. et al. | 2012
- 1138
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An IgG3 switch variant of rituximab mediates enhanced complement-dependent cytotoxicity against tumor cells with low CD20 expression levelsDerer, S. / Rossner, T. / Dechant, M. / Lohse, S. / Kellner, C. / Peipp, M. / Valerius, T. et al. | 2012
- 1139
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Analysis of the unique interaction of factor H with the periopathogen Treponema denticola: The paradox of factor H cleavageMiller, D. P. / McDowell, J. J. / Bell, J. K. / Fenno, J. C. / Marconi, R. T. et al. | 2012
- 1139
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Annexin A2 and A5 serve as new ligands for C1q on apoptotic cellsMartin, M. / Leffler, J. / Blom, A. M. et al. | 2012
- 1139
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Antibodies against chimeric pneumococcal proteins enhance complement deposition on Streptococcus pneumoniae with different genetic backgroundsDarrieux, M. / Goulart, C. / Rodrigues, D. / Leite, L. C. et al. | 2012
- 1140
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Assay for the pattern-recognition molecule CL-L1Axelgaard, E. / Jensen, L. / Thiel, S. / Jensenius, J. C. et al. | 2012
- 1140
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Anticomplementary activity of horse IgG and F(ab')2 antivenomsSquaiella-Baptistao, C. C. / Marcelino, J. R. / Cunha, L. E. / Gutierrez, J. M. / Tambourgi, D. V. et al. | 2012
- 1140
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Autoregulation of thromboinflammation on biomaterials and cells by a novel therapeutic coating techniqueTeramura, Y. / Nilsson, P. H. / Ekdahl, K. N. / Magnusson, P. U. / Qu, H. / Ricklin, D. / Hong, J. / Lambris, J. D. / Nilsson, B. et al. | 2012
- 1141
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Binding of iC3b to human dendritic cells does not alter the cells' phenotype and functionsBajtay, Z. / Sandor, N. / Erdei, A. et al. | 2012
- 1141
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Beta 2-glycoprotein I derived-peptides attenuate complement-mediated intestinal damageFleming, S. D. et al. | 2012
- 1141
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Bringing compstatin to the next level: Novel analogs with improved potency, pharmacokinetic profiles and administration options suitable for systemic applicationRicklin, D. / Qu, H. / Huang, Y. / Bai, H. / Reis, E. S. / Chen, H. / DeAngelis, R. A. / Tzekou, A. / Paraskevopoulos, G. / Li, Y. et al. | 2012
- 1141
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C1 interaction with Trypanosoma cruzi calreticulin mediates ex vivo infection of human placentaCastillo, C. / Duaso, J. / Maldonado, I. / Ramirez, G. / Valck, C. / Kemmerling, U. / Ferreira, A. et al. | 2012
- 1142
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C1-INH rescues erythrocytes from complement mediated destruction in autoimmune hemolytic anemiaWouters, D. / Stephan, F. / Strengers, P. / de Haas, M. / Brouwer, C. / Hagenbeek, T. / Oers, M. H. / Zeerleder, S. et al. | 2012
- 1142
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C1-inhibitor efficiently inhibits Escherichia coli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and coagulation activation in human whole bloodLandsem, A. / Nielsen, E. W. / Christiansen, D. / Mollnes, T. E. / Brekke, O. L. et al. | 2012
- 1143
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C1q secreted in the tumour microenvironment promotes tumour growth in the absence of complement activationBulla, R. / Agostinis, C. / Zorzet, S. / Tripodo, C. / Botto, M. / Tedesco, F. et al. | 2012
- 1143
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C3-glomerulopathy associated human factor H-related proteins 2 (CFHR2) and 5 (CFHR5) regulate complement C3b and TCCEberhardt, H. U. / Skerka, C. / Zipfel, P. F. / Hallstrom, T. / Hartmann, A. / Chen, Q. et al. | 2012
- 1143
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C1q induces a program of gene expression in amyloid beta injured neurons necessary for neuron survivalBenoit, M. E. / Hernandez, M. X. / Dinh, M. L. / Benavente, F. / Vasquez, O. / Tenner, A. J. et al. | 2012
- 1144
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C5 inhibition in mice prevents fatal C3 glomerulopathyLesher, A. / Miwa, T. / Sato, S. / Song, W. C. et al. | 2012
- 1144
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C5a is a target to prevent peritoneal tissue damage in acute peritoneal injury in ratsMizuno, T. / Mizuno, M. / Imai, M. / Suzuki, Y. / Kushida, M. / Yamada, K. / Noda, Y. / Maruyama, S. / Okada, H. / Okada, N. et al. | 2012
- 1144
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C3a and C5a mediated signalling on pulmonary CD103+ dendritic cells is critical for their migratory function in response to influenza infectionKandasamy, M. / Baalasubramanian, S. et al. | 2012
- 1145
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C5a/C5aR interaction mediates complement activation and thrombosis on endothelial cells in atypical hemolytic uremic syndrome (aHUS)Gastoldi, S. / Noris, M. / Macor, P. / Tedesco, F. / Banterla, F. / Bresin, E. / Donadelli, R. / Remuzzi, G. / Galbusera, M. et al. | 2012
- 1145
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C5a-C5aR interaction promotes kidney infection through acting on both renal and circulating cellsLi, K. / Choudhry, N. / Peng, Q. / Wang, N. / Lu, B. / Ma, L. / Sacks, S. H. / Zhou, W. et al. | 2012
- 1145
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C5a receptor signalling in dendritic cells regulates the development of maladaptive Th2 and Th17 immune responses in experimental allergic asthmaSchmudde, I. / Laumonnier, Y. / Strover, H. A. / Vollbrandt, T. / Konig, P. / Karsten, C. M. / Kohl, J. et al. | 2012
- 1146
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C5aR contributes to adipose tissue inflammation and insulin resistancePhieler, J. / Chung, K. J. / Chatzigeorgiou, A. / Lambris, J. D. / Chavakis, T. et al. | 2012
- 1146
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C5a/C5aR signaling is an important negative regulator of murine nature killer cell homeostasis and effector functionLi, K. / Wang, N. / Peng, Q. / Lu, B. / Ma, L. / Lambris, J. D. / Sacks, S. / Zhou, W. et al. | 2012
- 1147
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C5aR-dependent cell activation by physiological concentrations of C5a-desArg: Insights from a novel label-free cellular assayReis, E. S. / Chen, H. / Sfyroera, G. / Monk, P. N. / Kohl, J. / Ricklin, D. / Lambris, J. D. et al. | 2012
- 1147
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C5aR-dependent subversion of neutrophils and dysbiotic inflammationHajishengallis, G. / Krauss, J. L. / Jotwani, R. / Abe, T. / Triantafilou, M. / Triantafilou, K. / DeAngelis, R. A. / Lambris, J. D. et al. | 2012
- 1147
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C5aR regulates intestinal microbiota composition and controls the induction of gastrointestinal allergic hypersensitivityReinicke, A. T. / Herrmann, A. / Baer, F. / Sina, C. / Srinivas, G. / Kuenzel, S. / Baines, J. / Kohl, J. et al. | 2012
- 1148
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CD20 mAb-mediated C3b deposition and complement dependent cytotoxicity of tumor cells is enhanced by blocking the action of Factor ITaylor, R. P. / Lindorfer, M. A. / Beum, P. V. et al. | 2012
- 1148
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CD46 costimulation leads to enhanced T cell activation and microrna expressionKing, B. C. / Esguerra, J. / Qayyum, M. / Eliasson, L. / Kemper, C. / Blom, A. M. et al. | 2012
- 1148
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CD36 is not involved in alternative pathway-mediated complement-dependent cytotoxicity on proximal tubular epithelial cellsKenawy, H. I. / Bevington, A. / Stover, C. M. / Ali, Y. M. / Shwaeble, W. J. / Brunskill, N. J. et al. | 2012
- 1149
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Characterization of a human bispecific antibody against CD20/CD55 for the treatment of burkitt lymphomaMacor, P. / Mezzaroba, N. / De Maso, L. / Garrovo, C. / Biffi, S. / Sblattero, D. / Marzari, R. / Tedesco, F. et al. | 2012
- 1149
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CFHR1 gene variants and their pathophysiological relevanceTortajada, A. / Alba, M. / Pinto, S. / Lopez-Trascasa, M. / Sanchez-Corral, P. / Harris, C. L. / de Cordoba, S. R. et al. | 2012
- 1149
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CFHR5 nephropathy in a family without Cypriot ancestryMedjeral-Thomas, N. / Malik, T. H. / Toth, T. / Cook, T. / Tomson, C. / Pickering, M. C. et al. | 2012
- 1150
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Chemotherapy of breast cancer patients induces a shift in the glycosylation pattern of plasma complement components C3 and C4Oehler, R. / Schalko, C. / Michlmayr, A. / Bartsch, R. / Bergmann, M. / Bachleitner-Hofmann, T. et al. | 2012
- 1150
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Clinical analysis of peri-operative complement activation during renal ischemia-reperfusion injury following transplantationBlogowski, W. / Dolegowska, B. / Salata, D. / Budkowska, M. / Domanski, L. et al. | 2012
- 1150
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Cleavage of intracellular C3 into C3a and C3b by cathepsin L is required for human TH1 inductionLiszewski, K. M. / Kolev, M. / Bertram, P. / Yamamoto, H. / Leung, M. K. / Atkinson, J. P. / Kemper, C. et al. | 2012
- 1151
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Collagen-binding MSCRAMMS of Gram-positive bacteria inhibit complement activation via the classical pathwayYa-Ping, K. / Mingsong, K. / Liang, X. / Ross, C. L. / Liu, Q. / Murray, B. E. / Hook, M. et al. | 2012
- 1151
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CMAP: Putting complement on the map - one interaction at a timeReis, E. S. / Yang, K. / Ricklin, D. / Lambris, J. D. et al. | 2012
- 1152
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Collectin-11 (CL-K1):MASPs complex formation triggers activation of the complement lectin pathway-The fifth lectin pathway initiation complexMa, Y. J. / Skjoedt, M. O. / Garred, P. et al. | 2012
- 1152
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Combined inhibition of complement (C5) and CD14 markedly attenuates blood thrombogenicity, inflammation and hemodynamic changes in porcine sepsisBarratt-Due, A. / Thorgersen, E. B. / Egge, K. / Pischke, S. / Sokolov, A. / Hellerud, B. C. / Lindstad, J. K. / Pharo, A. / Nunn, M. / Scott, H. et al. | 2012
- 1152
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Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood modelSkjeflo, E. / Christiansen, D. / Lambris, J. D. / Espevik, T. / Nielsen, E. W. / Mollnes, T. E. et al. | 2012
- 1153
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Complement activation and phagocytosis in vitro of two strains of Borrelia burgdorferi S.LSandholm, K. / Henningsson, A. J. / Bergstrom, S. / Ernerudh, J. / Ekdahl, K. N. et al. | 2012
- 1153
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Complement activation mediates placental ischemia-induced hypertension in the rat independent of vascular endothelial growth factorRegal, J. F. / Lillegard, K. E. / Bauer, A. J. / Johnson, A. C. / Lojovich, S. J. / Marsh, H. / Gilbert, J. S. et al. | 2012
- 1153
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Complement activation and cell activation in the Alzheimer brainStretton, A. / Hakobyan, S. / Harris, C. / Morgan, P. / Neal, J. et al. | 2012
- 1154
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Complement alternative pathway activation is associated with severity of nonalcoholic steatohepatitisSegers, F. M. / Verdam, F. J. / de Jonge, C. / Boonen, B. / Bouvy, N. D. / Greve, J. W. / Buurman, W. A. / Rensen, S. S. et al. | 2012
- 1154
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Complement activity and regulation in premature, late premature and term neonatesGrumach, A. S. / Ceccon, M. E. / Rutz, R. / Kirschfink, M. et al. | 2012
- 1155
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Complement and antibody mediated killing of OPA-negative Neisseria gonorrhoeae by human neutrophilsAgarwal, S. / Ram, S. / Rice, P. A. et al. | 2012
- 1155
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Complement alternative pathway score and broad spectrum of acquired and hereditary complement abnormalities in patients with C3 glomerulopathyLe Quintrec, M. / Marinozzi, M. C. / Dragon-Durey, M. A. / Servais, A. / Roumenina, L. / Fakhouri, F. / Fremeaux-Bacchi, V. et al. | 2012
- 1155
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Complement anaphylatoxin C5a supports ovarian cancer development and controls the expression of VEGF164/165 isoformsNunez-Cruz, S. / Gimotty, P. A. / Guerra, M. W. / Connolly, D. C. / Wu, Y. Q. / DeAngelis, R. A. / Lambris, J. D. / Coukos, G. / Scholler, N. et al. | 2012
- 1156
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Complement C3 predicts cardiovascular event during 12 months of follow-up in haemodialysis patients and declines significantly with time on haemodialysisCarter, A. W. / Lines, J. Y. / Dunn, E. J. / Wright, M. J. / Carter, A. M. et al. | 2012
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Complement C5a and immune-complexes promote TNFa-dependent pathologies via stimulation of taceIssuree, P. D. / Maretzky, T. / Yarilina, A. / Ivashkiv, L. / Salmon, J. / Blobel, C. et al. | 2012
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Complement dependency of cholesterol crystal-induced inflammation - I. Pathway activation mechanisms, cytokine responses and endothelial cell activationNymo, S. / Samstad, E. O. / Niyonzima, N. / Bergseth, G. / Christiansen, D. / Ryan, L. / Brekke, O. L. / Lappegard, K. T. / Damas, J. K. / Latz, E. et al. | 2012
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Complement in action: An analysis of patent trends from 1976 through 2011DeAngelis, R. A. / Yang, K. / Reed, J. E. / Ricklin, D. / Lambris, J. D. et al. | 2012
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Complement dependency of cholesterol crystal-induced inflammation - II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP)Niyonzima, N. / Samstad, E. O. / Aune, M. H. / Ryan, L. / Damas, J. K. / Wright, S. / Sandanger, O. / Aukrust, P. / Latz, E. / Mollnes, T. E. et al. | 2012
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Complement inhibitor C4b-binding protein is involved in protein AA amyloidosisSjolander, J. / Lundmark, K. / Wetsel, R. / Blom, A. M. / Westermark, G. T. et al. | 2012
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Complement inhibition is neuroprotective in a mouse model of leprosyIdrissi, N. B. / Rosa, P. / Fluiter, K. / Troost, D. / Morgan, P. / Das, P. / Baas, F. / Ramaglia, V. et al. | 2012
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Complement mediated adverse drug effects: Prediction with complement assays and prevention with tolerance inductionSzebeni, J. et al. | 2012
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Complement pathways in periodontitis and targeted therapeutic interventionAbe, T. / DeAngelis, R. A. / Lambris, J. D. / Hajishengallis, G. et al. | 2012
- 1159
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Complement mediated protection against Streptococcus pneumoniae induced by PspA-PdT immunizationGoulart, C. / Darrieux, M. / Rodrigues, D. / Leite, L. C. et al. | 2012
- 1160
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Compstatin induces allosteric changes in C3 and C3b and changes their ligand binding patternChen, H. / Ricklin, D. / Lambris, J. D. et al. | 2012
- 1160
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Complement receptor C3aR modulates platelet function and thrombosisSauter, R. J. / Fahrleitner, M. / Schleicher, R. / Kraemer, B. / Gawaz, M. / Lambris, J. D. / Langer, H. F. et al. | 2012
- 1160
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Complement- and platelet-mediated shuttling of blood-borne bacteria to CD8A+ dendritic cellsBroadley, S. / Graef, P. / Plaumann, A. / Seidlmeier, A. / Warnisch, A. / Busch, D. H. / Verschoor, A. et al. | 2012
- 1160
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Control of arthritis by local synthesis of recombinant antibody neutralizing C5Macor, P. / Durigutto, P. / Ziller, F. / De Maso, L. / Fischetti, F. / Marzari, R. / Sblattero, D. / Tedesco, F. et al. | 2012
- 1161
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CR3 is the main phagocytotic receptor for iC3b opsonized particles on dendritic cells while CR4 plays supporting roleSandor, N. / Bajtay, Z. / Erdei, A. et al. | 2012
- 1161
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Critical role of C5aR signals in bone marrow-derived cells in an accelerated lupus nephritis modelBao, L. / Haas, M. / Quigg, R. J. et al. | 2012
- 1161
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CR3-bearing monocytes are protective in experimental tubulointerstitial nephritis (TIN)Chaves, L. D. / Bao, L. / Wang, Y. / Quigg, R. J. et al. | 2012
- 1162
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Crry deficiency exacerbates atherosclerosis in apoE deficient miceJayanthi, A. / Jackson, C. L. / Morgan, P. / Hughes, T. R. et al. | 2012
- 1162
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CSMD1 protein, a new complement inhibitorEscudero-Esparza, A. / Kalchishkova, N. / Blom, A. M. et al. | 2012
- 1162
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De novo protein design of agonists and antagonists of C5a receptorsMonk, P. N. / Bellows-Peterson, M. L. / Smadbeck, J. / Floudas, C. A. / Kieslich, C. A. / Morikis, D. / Woodruff, T. M. et al. | 2012
- 1163
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Deciphering the interactions of Streptococcus pyogenes and the complement system using a novel mouse infection modelErmert, D. / Shaughnessy, J. / Frick, I. M. / Malmstrom, J. / Bjorck, L. / Rice, P. A. / Ram, S. / Blom, A. et al. | 2012
- 1163
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Deletion of Crry and DAF on murine platelets stimulates thrombopoiesis and increases fH-dependent resistance of peripheral platelets to complement attackBarata, L. / Miwa, T. / Song, W. C. et al. | 2012
- 1163
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Determinants of the substrate specificity of the complement initiating protease, C1rWijeyewickrema, L. C. et al. | 2012
- 1164
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Distinct roles of the complement C5a receptors C5aR and C5L2 in bacterial and bacterial component-induced inflammation in human whole bloodAn, L. L. / Kolbeck, R. / Fung, M. et al. | 2012
- 1164
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Developmental abnormalities in Masp1/3-deficient miceTakahashi, M. / Endo, Y. / Fujita, T. et al. | 2012
- 1164
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Development of humanized complement factor H transgenic mice to interrogate the effect of age-related macular degeneration risk associated variants in vivoKelly, U. / Ding, J. d. / Landowski, M. / Groelle, M. / Jiang, H. / Skiba, N. / Frank, M. / Rickman, C. B. et al. | 2012
- 1165
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Effect of regulation of glycolysis on tumor inflammation and immune statusInoue, N. / Ohashi, T. / Akazawa, T. et al. | 2012
- 1165
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Effects of C1 esterase inhibitor on attenuation of ischemia/reperfusion injury in a rat hind limb modelDuhrkop-Sisewitsch, C. / Walti, Y. B. / Spirig, R. / Miescher, S. / Nolte, M. W. / Spycher, M. / Rieben, R. et al. | 2012
- 1165
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Does Salmonella lipopolysaccharides with sialic acid inhibit C3 activation?Futoma-Koloch, B. / Godlewska, U. / Guz-Regner, K. / Zarzycki, M. / Klausa, E. / Bugla-Ploskonska, G. et al. | 2012
- 1166
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Endogenous and natural complement inhibitor attenuates myocardial injury and arterial thrombogenesisSkjoedt, M. O. / Pavlov, V. I. / Tan, Y. S. / Rosbjerg, A. / Garred, P. / Stahl, G. L. et al. | 2012
- 1166
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Effects of MASP-1 on blood coagulation studied by thrombelastometryAeschliman, J. / Dobo, J. / Gal, P. / Schroeder, V. et al. | 2012
- 1166
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Electron microscopy reveals coexistence of distinct conformations of iC3bAlcorlo, M. / Rodriguez-Gallego, C. / Yebenes, H. / Tortajada, A. / Subias, M. / de Cordoba, S. R. / Llorca, O. et al. | 2012
- 1167
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Enzymatic properties of the MASP-3 serine protease domain and crystal structure of its complex with ecotinGaboriaud, C. / Gupta, R. / Martin, L. / Lacroix, M. / Arlaud, G. J. / Rossi, V. / Thielens, N. M. et al. | 2012
- 1167
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Escherichia coli-induced coagulation activation and pentraxin 3 release is highly dependent on complement and CD14Brekke, O. L. / Landsem, A. / Fure, H. / Christiansen, D. / Nielsen, E. W. / Lambris, J. D. / Mollnes, T. E. et al. | 2012
- 1167
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Endothelial cells injured by the thrombotic microangiopathy-inducing drug cyclosporin release complement-activating microparticlesRenner, B. / Klawitter, J. / Ferreira, V. P. / Christians, U. / Holers, M. / Thurman, J. M. et al. | 2012
- 1168
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Evidence of classical complement activation during blood-biomaterial interaction in LDL apheresisLudviksen, J. K. / Hovland, A. / Lappegard, K. T. / Mollnes, T. E. et al. | 2012
- 1168
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Evolution of the thioester-containing protein genes in the arthropodaSekiguchi, R. / Nonaka, M. et al. | 2012
- 1168
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Essential role of surface-bound complement factor H in controlling immune complex-induced arthritisBanda, N. K. / Mehta, G. / Ferreira, V. P. / Cortes, C. / Pangburn, M. K. / Arend, W. P. / Holers, V. M. et al. | 2012
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Expression of complement factors and functional C5a receptors in human embryonic stem cells, and induced pluripotent stem cellsHawksworth, O. A. / Coulthard, L. G. / Taylor, S. M. / Wolvetang, E. J. / Woodruff, T. M. et al. | 2012
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Expression of the complement system is upregulated in subcutaneous adipocytes from non-obese hypertriglyceridemic subjects and is associated with local insulin resistanceVan Greevenbroek, M. M. / Ghosh, S. / van der Kallen, C. J. / Brouwers, M. C. / Schalkwijk, C. G. / Stehouwer, C. D. et al. | 2012
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Extracellular adherence protein (Eap) of Staphylococcus aureus evades innate immunity by inhibiting complement activation and neutrophil elastaseStapels, D. A. / Ramyar, K. X. / Ricklin, D. / Milder, F. J. / Bischoff, M. / Herrmann, M. / Geisbrecht, B. V. / Lambris, J. D. / von Kockritz-Blickwede, M. / Kessel, K. P. et al. | 2012
- 1170
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Factor H-dependent regulation of the alternative pathway of complement by Meningococci that lack FHBP, NSPA, capsule and lipooligosaccharide sialic acidLewis, L. A. / Vasudhev, S. / Shaughnessy, J. / Ram, S. et al. | 2012
- 1170
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Factor XII missense mutation THR328LYS in three Brazilian familiesCordeiro, E. / Stieber, C. / Constantino-Silva, R. N. / Fusaro, G. / Cichon, S. / Grumach, A. S. et al. | 2012
- 1171
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Ficolin-2 properties differ between serum and plasmaHein, E. / Bay, J. T. / Munthe-Fog, L. / Garred, P. et al. | 2012
- 1171
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Formation of an immune complex resembling C5b-9 via coagulation factors and plateletsGorham, R. D. / Urbanus, R. T. / Kuipers, A. / Morikis, D. / Rooijakkers, S. H. et al. | 2012
- 1171
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Familial membranoproliferative glomerulonephritis type I associated with a functionally significant mutation in complement factor HWong, E. / Anderson, H. / Challis, R. / Herbert, A. / Barlow, P. / Fluck, N. / Humphrey, A. / MacLeod, A. / Marchbank, K. / Kavanagh, D. et al. | 2012
- 1172
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Functional analysis of the complement system in oligoarticular juvenile idiopathic arthritisBrunner, J. K. / Prelog, M. / Riedl, M. / Giner, T. / Hofer, J. / Zimmerhackl, L. B. et al. | 2012
- 1172
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Functional C1-inhibitor level increases during attacks of hereditary angioedemaVarga, L. A. / Csuka, D. / Fust, G. / Zotter, Z. / Szabo, E. / Czaller, I. / Farkas, H. et al. | 2012
- 1172
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Free heme transforms endothelial cells into alternative pathway activators. Implications for the hemolytic and uremic syndromeFrimat, M. / Tabarin, F. / Halbwachs, L. / Poitou, C. / Dimitrov, J. / Fremeaux-Bacchi, V. / Roumenina, L. et al. | 2012
- 1173
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GAPDH exposed on human and pneumococcal cell surface is a novel C1q ligandTacnet-Delorme, P. / Terrasse, R. / Moriscot, C. / Perard, J. / Schoehn, G. / Vernet, T. / Thielens, N. M. / Frachet, P. et al. | 2012
- 1173
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Global gene expression analysis of the effects of sublytic complement on CT26 colon carcinoma cells using microarray technologyTowner, L. D. / Kolev, M. V. / Morgan, P. B. / Hughes, T. R. et al. | 2012
- 1173
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High performance fluid-based array using protein AG for coupling antibodies to carboxylated microspheres for quantification of 10 complement protein componentsNascimento, E. J. / Melo, K. M. / Marques, T. A. et al. | 2012
- 1174
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How does degradation of neutrophil extracellular traps correlate with the activity of systemic lupus erythematosus?Leffler, J. / Gullstrand, B. / Lood, C. / Tyden, H. / Truedsson, L. / Martin, M. / Blom, A. M. / Bengtsson, A. A. et al. | 2012
- 1174
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Human CR1 as a target for selective treatment of autoimmune and allergic diseases in humanised SCID miceTchorbanov, A. I. / Kerekov, N. S. / Mihaylova, N. M. et al. | 2012
- 1174
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Higher levels of complement C3a (activated C3) are cross-sectionally associated with higher carotid media thickness and lower ankle-arm blood pressure index: The CODAM studyHertle, E. / van Greevenbroek, M. M. / van der Kallen, C. J. / Geijselaers, S. L. / Ferreira, I. / Feskens, E. J. / Schalkwijk, C. G. / Stehouwer, C. D. et al. | 2012
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Identification of a novel mode of complement activation on stimulated platelets mediated by properdinSaggu, G. / Cortes, C. / Emch, H. N. / Ramirez, G. / Worth, R. G. / Ferreira, V. P. et al. | 2012
- 1175
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Identification of a novel C5a-inhibiting human and mouse-specific Spiegelmer for treatment of septic shock and its proof of concept in the CLP mouse modelVater, A. / Hoehlig, K. / Maasch, C. / Buchner, K. / Purschke, W. G. / Klussmann, S. et al. | 2012
- 1175
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Hunting for biomarkers: The complement system in Alzheimer's diseaseHakobyan, S. / Aiyaz, M. / Stretton, A. / Sattlecker, M. / Dobson, R. / Harris, C. / Morgan, P. / Lovestone, S. et al. | 2012
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Identification of Jagged1 as a novel ligand for CD46: An interaction required for normal induction and regulation of human TH1 responsesLe Friec, G. / Sheppard, D. / Karsten, C. M. / Whiteman, P. / Shamoun, S. / Laing, A. / Waddington, S. N. / McDonnell, J. M. / Fremeaux-Bacchi, V. / Couzi, L. et al. | 2012
- 1176
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Identification of critical core amino acids of a major linear C1q epitope recognized by SLE auto-antibodiesVanhecke, D. / Trendelenburg, M. et al. | 2012
- 1177
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IgM-mediated enhancement of immune responsesDing, Z. / Bergman, A. / Rutemark, C. / Heyman, B. et al. | 2012
- 1177
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Identification of the gC1qR binding sites for HIV-1 gp41 and HCV core proteinPednekar, L. / Tumma, N. / Valentino, C. / Hosszu, K. K. / Valentino, A. / Peerschke, E. I. / Kishore, U. / Ghebrehiwet, B. et al. | 2012
- 1177
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IgG2a immune complexes enhance C5a-mediated inflammationWagner, M. / Karsten, C. M. / Kohl, J. et al. | 2012
- 1178
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Inhibition of ABO incompatibility using a novel small peptideSharp, J. A. / Mauriello, C. T. / Cunnion, K. M. / Krishna, N. K. et al. | 2012
- 1178
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In vivo dissection of the contribution of fB, fD and properdin to alternative pathway activation on membranesWu, X. / Bertram, P. / Xu, T. / Hourcade, D. / Stover, C. / Atkinson, J. P. et al. | 2012
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Immune evasion in leptospira: The secretion of metalloproteases that directly cleave complement proteinsFraga, T. R. / Courrol, D. S. / Valencia, M. M. / Vasconcelos, S. A. / Barbosa, A. S. / Isaac, L. et al. | 2012
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Investigation of complement activation by neutral liposomesKlapper, Y. / Hamad, O. / Teramura, Y. / Leneweit, G. / Nienhaus, G. U. / Ekdahl, K. N. / Nilsson, B. et al. | 2012
- 1179
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Inhibition of complement-dependent cytotoxicity by C9-binding cellular stress proteinsRozenberg, P. / Saar, M. / Donin, N. / Moskovich, O. / Fishelson, Z. et al. | 2012
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Inhibition of biomaterial-induced complement activation attenuates the inflammatory host response to implantationKourtzelis, I. / Rafail, S. / DeAngelis, R. A. / Foukas, P. G. / Ricklin, D. / Lambris, J. D. et al. | 2012
- 1180
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Involvement of the murine epididymal C4BP in the reproductive system but not in the complement systemNonaka, M. I. / Kudo, A. / Kawakami, H. / Yoshida, K. / Yoshida, M. / Nonaka, M. et al. | 2012
- 1180
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Knockdown of the membrane regulators CD46, CD55, CD59 by sirna enhances complement- and macrophage-dependent anti-tumor effects of rituximab and Campath-1HMamidi, S. / Teufel, C. / Kirschfink, M. et al. | 2012
- 1180
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Large spectrum of Factor B aHUS mutations functional consequences on the C3 convertase - From gain to lack of functional consequenceRoumenina, L. T. / Vergoz, L. / Rybkine, T. / Donadelli, R. / Cayla, M. / Smith, R. / Noris, M. / Halbwachs-Mecarelli, L. / Fremeaux-Bacchi, V. et al. | 2012
- 1181
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Ligand-induced dimerisation of the complement C5aR and C5L2 receptors by C5a but not C5a-des ArgCroker, D. E. / Halai, R. / Fairlie, D. P. / Cooper, M. A. et al. | 2012
- 1181
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Large-scale generation of IgG-depleted human complement source for functional bacterial immunoassaysBrookes, C. / Kuisma, E. / Alexander, F. / Taylor, S. / Gorringe, A. et al. | 2012
- 1181
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Leptospiral immunoglobulin-like proteins interact with plasminogen to escape complement mediated-killingValencia, M. M. / Fraga, T. R. / Silva, L. B. / Monaris, D. / Abreu, P. A. / Barbosa, A. S. / Isaac, L. et al. | 2012
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LJM19, a salivary protein from the sand fly vector that transmits leishmaniasis, is a novel inhibitor of the classical pathway of complementFerreira, V. P. / Saggu, G. / Pereira, M. H. / Araujo, R. N. / Vale, V. F. / Lima-III, K. F. / Pangburn, M. K. / MC.Ribeiro, J. / Gontijo, N. F. / Collin, N. et al. | 2012
- 1182
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Local and not systemic factor H production dictates risk of age-related macular degeneration in liver transplant recipientsKhandhadia, S. / Hakobyan, S. / Heng, L. Z. / Gibson, J. / Adams, D. H. / Alexander, G. J. / Gibson, J. M. / Martin, K. / Menon, G. / Nash, K. et al. | 2012
- 1183
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Low levels of mannan-binding lectin or ficolins are not associated with an increased risk of cytomegalovirus disease in HIV-infected patients - A case-control study nested within the Swiss HIV Cohort StudyEgli, A. / Schaefer, J. / Osthoff, M. / Thiel, S. / Mikkelsen, C. / Rauch, A. / Hirsch, H. H. / Bucher, H. / Young, J. / Jensenius, J. C. et al. | 2012
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Localised inhibition of coagulation limits acute complement mediated damage in high risk renal transplantationKaregli, J. / Farrar, C. / Melchionna, T. / Horsfield, C. / Dorling, A. / Smith, R. / Sacks, S. et al. | 2012
- 1183
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M-ficolin binds specifically to two capsulare structures of Streptococcus pneumoniaeKjaer, T. / Hansen, A. / Sorensen, U. S. / Jensenius, J. C. / Holm, A. T. / Sorensen, G. L. / Thiel, S. et al. | 2012
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Mannan-binding lectin associated serine protease-3 is a novel predictor of overall survival in patients with metastatic renal cell carcinomaJensenius, J. C. / Vedel, P. / Thiel, S. / Donskov, F. N. et al. | 2012
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Mannan-binding lectin in pregnancy: Analysis of serum concentrations/genotypes with regard to clinical data in 212 womenPotlukova, E. / Kralikova, P. / Jiskra, J. / Limanova, Z. / Telicka, Z. / Springer, D. / Trendelenburg, M. et al. | 2012
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Maggot excretions and secretions reduce complement activationCazander, G. / Schreurs, M. W. / Juke, G. N. / Nibbering, P. H. et al. | 2012
- 1185
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Mannose-binding lectin and lectin pathway in subarachnoid hemorrhage patientsZangari, R. / Zoerle, T. / Orsini, F. / Parrella, S. / Conte, V. / Stocchetti, N. / Zanier, E. R. / De Simoni, M. G. et al. | 2012
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Mannose-binding lectin deficiency reduces functional deficits and histological damage after experimental traumatic brain injuryLonghi, L. / Orsini, F. / Parrelia, S. / Fedele, N. / Stocchetti, N. / De Simoni, M. G. et al. | 2012
- 1186
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MASP levels in cardio- and cerebrovascular diseases: A pilot studyFrauenknecht, V. / Thiel, S. / Arnold, M. / Schmid, J. P. / Saner, H. / Schroeder, V. et al. | 2012
- 1186
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MBL-associated serine protease (MASP)-1/3 promotes the initiation of the alternative pathway activationKodama, T. / Takahashi, M. / Iwaki, D. / Sekine, H. / Endo, Y. / Fujita, T. et al. | 2012
- 1186
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MBL/ficolin associated protein-1 inhibits the complex formation between MASPs and MBLRosbjerg, A. / Skjoedt, M. O. / Garred, P. et al. | 2012
- 1187
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MCP (CD46) autoantibodies are associated with atypical hemolytic uremic syndromeBennaceur, K. / Hunze, E. M. / Liszewski, M. K. / Bertram, P. / Staniforth, S. J. / Strain, L. / Wilson, V. / Atkinson, J. P. / Goodship, T. H. / Marchbank, K. J. et al. | 2012
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Membrane cofactor protein (MCP) haplotype, which predisposes to atypical hemolytic and uremic syndrome, has no consequence on neutrophils and endothelial cells MCP levels or on HUVECs ability to activate complementfrimat, M. / Roumenina, L. T. / Tabarin, F. / Halbwachs-Mecarelli, L. / Fremeaux-Bacchi, V. et al. | 2012
- 1187
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Membrane attack complex deposition on gram-positive bacteriaBerends, E. T. / Dekkers, F. / Nijland, R. / van Strijp, J. A. / Rooijakkers, S. H. et al. | 2012
- 1188
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Molecular and functional characterization of the interaction of L-ficolin with Streptococcus pneumoniaeStermann, E. / Lacroix, M. / Gout, E. / Laffly, E. / Pedersen, C. M. / Schmidt, R. R. / Vernet, T. / Gaboriaud, C. / Di Guilmi, A. M. / Thielens, N. M. et al. | 2012
- 1188
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Modulation of human T cell function by exogenous and endogenous C3Erdei, A. / Torok, K. et al. | 2012
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Microbial pathogens of diverse origin inhibit the terminal complement pathway: A common immune evasion strategy?Hallstrom, T. / Siegel, C. / Luo, S. / Morgelin, M. / Hammerschmidt, S. / Skerka, C. / Kraiczy, P. / Zipfel, P. F. et al. | 2012
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Natural inhibitors of the lectin pathwayParej, K. / Dobo, J. / Zavodszky, P. / Gal, P. et al. | 2012
- 1189
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Negative regulation of NK cell function through engagement of CR3 with its complement ligandLi, K. / Peng, Q. / Wang, N. / Li, Z. / Sacks, S. / Zhou, W. et al. | 2012
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Negative regulation of human nature killer cells by complementMin, X. / Wei, Y. / Li, Z. / Sacks, S. / Zhou, W. / Li, K. et al. | 2012
- 1190
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NGR conjugated pegylated polymeric nanoparticles for targeted delivery of docetaxelGupta, M. / Agrawal, G. P. / Vyas, S. P. et al. | 2012
- 1190
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New insights into the inhibitory function of CR1 on human B lymphocytes; the functional consequences of the crosstalk between BCR, TLR9 and CR1Kremlitzka, M. / Valent, B. / Erdei, A. et al. | 2012
- 1190
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New crossroads between complement and apoptosis after traumaHuber-Lang, M. S. / Denk, S. / Lambris, J. D. / Perl, M. et al. | 2012
- 1191
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Non-proteolytically activated C3 promotes binding of activated platelets and platelet-derived microparticles to leukocytes via CD11b/CD18Hamad, O. A. / Ekdahl, K. N. / Nilsson, B. et al. | 2012
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Novel monoclonal antibodies to C3d that target and identify in living animals sites of complement activationThurman, J. M. / Kulik, L. / Mitchell, L. M. / Hourcade, D. E. / Hannan, J. P. / Coughlin, B. / Woodell, A. S. / Pickering, M. C. / Rohrer, B. / Holers, M. et al. | 2012
- 1192
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Novel mouse anti-mouse monoclonal antibodies that block either the ligand or receptor member of the CR2-C3d interaction pair impair antigen-specific humoral immune responses to model antigensKulik, L. / Thurman, J. M. / Hannan, J. P. / Tomlinson, S. / Holers, M. V. et al. | 2012
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Peripheral gangrenes in children with atypical hemolytic uremic syndromeMalina, M. / Gulati, A. / Bagga, A. / Majid, M. A. / Simkova, E. / Schaefer, F. et al. | 2012
- 1192
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On the conformational flexibility of C3b: A molecular insight into activation and transformation of a major complement effectorGipson, B. / Moll, M. / Ricklin, D. / Lambris, J. D. / Kavraki, L. E. et al. | 2012
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Phagocytosis of Escherichia coli in human whole blood: Early complement dependency is succeeded by late CD14 dependency over timeChristansen, D. / Stenvik, J. / Brekke, O. L. / Lambris, J. D. / Espevik, T. / Mollnes, T. E. et al. | 2012
- 1193
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Pre-transplant ficolin-3 levels are associated with kidney allograft survivalBay, J. T. / Hein, E. / Sorensen, S. S. / Hansen, J. M. / Garred, P. et al. | 2012
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Pinpointing the time and cause of fetal demise in the Crry^-^/^- embryoTriebwasser, M. P. / Wu, X. / Hourcade, D. / Atkinson, J. P. et al. | 2012
- 1194
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Prolonged voltage-gated calcium channel activation by sublytic complement activation in retinal pigment epithelium, a mechanism for controlling VEGF secretionRohrer, B. / Kunchithapautham, K. / Genewski, A. / Strauss, O. et al. | 2012
- 1194
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Premolis semirufa envenomation, disease affecting rubber tappers of the Amazon: Searching for caterpillar-bristles toxic components acting on the complement systemBoas, I. M. / de Andrade, R. M. / Pidde-Querioz, G. / Portaro, F. C. / van den Berg, C. W. / Tambourgi, D. V. et al. | 2012
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Production of functional full-length recombinant human C1qBally, I. / Ancelet, S. / Moriscot, C. / Bonnet, F. / Daniel, R. / Schoehn, G. / Arlaud, G. J. / Thielens, N. M. et al. | 2012
- 1195
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Properdin and complement amplification loop in the pathogenesis of experimental autoimmune myasthenia gravis (EAMG)Soltys, J. / Stover, C. / Wu, X. et al. | 2012
- 1195
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Properdin binding to the surface of leptospira promotes complement activation and controls proliferation of non-pathogenic bacteria in vitroMartinez, A. G. / Ferreira, V. P. / Fraga, T. R. / Vasconcellos, S. d. / Daha, M. R. / Barbosa, A. S. / Isaac, L. et al. | 2012
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Purification and biochemical characterization of functional complement factor H from human plasma fractionsBrandstatter, H. / Schulz, P. / Polunic, I. / Kannicht, C. / Kohla, G. / Romisch, J. et al. | 2012
- 1196
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Properdin is increased after allergen challenge of asthmatic patients and contributes to OVA-induced airway inflammation and AHR at the effector phase by enhancing C3a generation in miceWang, Y. / Ducka-Kokalari, B. / Redai, I. / Miwa, T. / Sato, S. / Gullipalli, D. / Haczku, A. / Song, W. C. et al. | 2012
- 1196
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Properdin deficiency exacerbates C3 glomerulopathy in factor H-deficient miceRuseva, M. M. / Vernon, K. A. / Lesher, A. M. / Schwaeble, W. J. / Ali, Y. M. / Botto, M. / Cook, H. T. / Song, W. C. / Stover, C. M. / Pickering, M. C. et al. | 2012
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Recombinant anti-human and anti-porcine CD14 antibodiesLau, C. / Gunnarsen, K. S. / Hoydahl, L. S. / Berntzen, G. / Stokes, C. R. / Espevik, T. / Sandlie, I. / Mollnes, T. E. et al. | 2012
- 1197
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Rational engineering of a novel complement regulator-based therapeutic affords triple targeting of host surfaces and pathway-specific inhibition of complement activationSchmidt, C. Q. / Bai, H. / Lin, Z. / Risitano, A. M. / Barlow, P. N. / Ricklin, D. / Lambris, J. D. et al. | 2012
- 1197
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Rat adipose tissue-derived stromal cells in a low serum medium attenuate peritoneal injuries in rat zymosan-induced peritonitisKim, H. / Mizuno, M. / Furuhashi, K. / Katsuno, T. / Ozaki, T. / Yasuda, K. / Tsuboi, N. / Imai, E. / Matsuo, S. / Ito, Y. et al. | 2012
- 1198
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Reduced activity of the lectin complement pathway in cystic fibrosisKeizer, S. M. / Brouwer, N. / Frakking, F. N. / Wouters, D. / Kuijpers, T. W. et al. | 2012
- 1198
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Recombinant mouse factor H from Pichia pastorisKerr, H. / Herbert, A. H. / Richards, A. / Barlow, P. N. et al. | 2012
- 1198
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Reduction of complement regulator CD59 expression on human kidney cells by Shiga toxin 2Ehrlenbach, S. / Rosales, A. / Orth, D. / Wurzner, R. et al. | 2012
- 1199
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Robust measurement of rat complement system activation with novel ELISA-based assaysKotimaa, J. P. / Leijtens, S. / Daha, M. R. / van Kooten, C. / Rutjes, H. W. et al. | 2012
- 1199
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Response gene to complement-32 is a potential biomarker of relapses in multiple sclerosisRus, H. / Tegla, C. / Cudrici, C. / Azimzadeh, P. / Rus, V. / Florin, N. et al. | 2012
- 1199
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Regulation of complement in whole blood by heparin molecularly imprinted polymer particlesHuang, S. / Nilsson, P. H. / Sandholm, K. / Elmlund, L. / Nicholls, I. A. / Ekdahl, K. N. et al. | 2012
- 1200
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Role of complement in a murine model of peanut-induced anaphylaxisKodama, T. / Endo, Y. / Takahashi, M. / Iwaki, D. / Machida, T. / Fujita, T. / Sekine, H. et al. | 2012
- 1200
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Role of complement in modulation of TH2 response in prostate cancer cellsYamamoto, H. / Fara, A. / Chandra, A. / Cardone, J. / Dasgupta, P. / Kemper, C. et al. | 2012
- 1200
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Role of complement in the early stages of viral infectionsLanglois, M. P. / Tarrab, E. / Lamarre, A. et al. | 2012
- 1201
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Saliva activates the complement systemGunput, S. T. / Ligtenberg, A. J. / Brouwer, M. / Wouters, D. / Veerman, E. C. et al. | 2012
- 1201
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Role of the alternative pathway of complement in ischemia/reperfusion and chronic graft injury in a mouse model of kidney allograftCavinato, R. A. / Azzollini, N. / Casiraghi, F. / Todeschini, M. / Remuzzi, G. / Noris, M. et al. | 2012
- 1201
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Role of properdin in systemic AP complement consumption caused by Crry deficiencyLesher, A. / Miwa, T. / Sato, S. / Mohammed, I. / Song, W. C. et al. | 2012
- 1202
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Screening patients with inherited GPI anchor deficiency to establish concept of the new diseaseMurakami, Y. / Inoue, N. / Maeda, Y. / Takahashi, Y. / Kinoshita, T. et al. | 2012
- 1202
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Serological analysis of complement in patients with neuromyelitis opticaNytrova, P. / Trendelenburg, M. / Horakova, D. / Zbornikova, P. / Havrdova, E. / Potlukova, E. et al. | 2012
- 1203
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Silencing of mortalin, a regulator of the complement membrane attack complex, as anticancer adjuvant therapyDonin, N. / Ziporen, L. / Masarwa, M. / Ben-Moshe, O. / Kirschfink, M. / Fishelson, Z. et al. | 2012
- 1203
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Signals through CR3 generate alternatively activated macrophages (AAMs) which are protective in complement-dependent glomerulonephritis (GN)Alexander, J. J. / Chaves, L. / Quigg, R. J. et al. | 2012
- 1203
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Specific serum immunoglobulin recognizing staphylococcal wall teichoic acid induces complement-mediated opsonophagocytosis against Staphylococcus aureusLee, B. L. / Jung, D. J. / Kurokawa, K. / Matsushita, M. / Takahashi, S. et al. | 2012
- 1204
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Staphylococcal proteases aid evasion of human complement systemJusko, M. / Potempa, J. / Kantyka, T. / Bielecka, E. / Miller, H. K. / Kalinska, M. / Dubin, G. / Garred, P. / Shaw, L. N. / Blom, A. M. et al. | 2012
- 1204
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Staphylococcus aureus surface protein SdrE binds the complement regulator factor H to evade the immune responseSharp, J. A. / Echague, C. G. / Hair, P. S. / Ward, M. D. / Nyalwidhe, J. O. / Geoghegan, J. A. / Foster, T. J. / Cunnion, K. M. et al. | 2012
- 1204
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Specificity and mechanism of assembly of C4b binding proteinCaesar, J. J. / Turki, I. / Hill, F. / Lea, S. M. et al. | 2012
- 1205
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Structural characterization of the N-terminal region of Streptococcus pneumonia surface protein CHerbert, A. P. / Makou, E. / Barlow, P. N. et al. | 2012
- 1205
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Structural basis for activation of the complement system by C4 cleavageAndersen, G. R. / Kidmose, R. T. / Laursen, N. S. / Dobo, J. / Kjaer, T. R. / Sirotkina, S. / Yatime, L. / Sottrup-Jensen, L. / Thiel, S. / Gal, P. et al. | 2012
- 1205
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Survival of bacterial blood isolates in serum or blood can be impaired with factor H fragment CFH5-7Haapasalo-Tuomainen, K. / Johansson, T. / Kirveskari, J. / Kuusela, P. / Jokiranta, S. et al. | 2012
- 1205
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Structural findings in complement factor H-related proteins unravel the pathogenesis of C3 glomerulopathyde Jorge, E. G. / Caeser, J. / Malik, T. H. / Patel, M. M. / Colledge, M. / Johnson, S. / Harris, C. L. / Pickering, M. C. / Lea, S. M. et al. | 2012
- 1206
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Systemic CD14-inhibition attenuates local inflammatory responses organ-dependently in porcine Escherichia coli-sepsisThorgersen, E. B. / Pischke, S. / Barratt-Due, A. / Fure, H. / Lindstad, J. K. / Pharo, A. / Hellerud, B. C. / Mollnes, T. E. et al. | 2012
- 1206
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Targeted deep sequencing of the complement system in complementopathiesTriebwasser, M. P. / Bertram, P. / Laivuori, H. / Kimberly, R. P. / Salmon, J. E. / Atkinson, J. P. et al. | 2012
- 1206
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Synchronized transcription of the three C1q genes in dendritic cells - Molecular and chromosomal mechanismsTan, C. S. / Chen, G. / Teo, D. B. / Lu, J. et al. | 2012
- 1207
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Targeting MBL in cerebral ischemia induces long lasting protection with a wide therapeutic windowOrsini, F. / Parrella, S. / Villa, P. / Zangari, R. / Zanier, E. R. / Stravalaci, M. / Fumagalli, S. / Ottria, R. / Reina, J. / Paladini, A. et al. | 2012
- 1207
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Targeted silencing of mCRP (CD46, CD55, CD59) by siRNA encapsulated in transferrin-liposomes specifically sensitizes cancer cells to complement attackMamidi, S. / Kirschfink, M. et al. | 2012
- 1208
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The C-type lectin of the aggrecan G3 domain activates complementFurst, C. M. / Morgelin, M. / Heinegard, D. / Aspberg, A. / Blom, A. et al. | 2012
- 1208
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Terminal complement pathway therapy in experimental traumatic brain injuryRamaglia, V. / Opperhuizen, A. / Fluiter, K. / Morgan, P. B. / Baas, F. et al. | 2012
- 1208
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Targeting the glomerular basement membrane to control unwanted complement activationHunze, E. M. / Sheerin, N. S. / Marchbank, K. J. et al. | 2012
- 1209
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The complement anaphylatoxin C3a is critical in generating both innate and adaptive immune responses to Listeria monocytogenes due to its indispensible role in immune cell survivalMueller-Ortiz, S. L. / Morales, J. E. / Clark, A. / Wetsel, R. A. et al. | 2012
- 1209
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The C3a receptor mediates protection from intestinal ischemia reperfusion injuries by impairing neutrophil mobilizationWoodruff, T. M. / Wu, M. C. / Brennan, F. H. / Wetsel, R. A. / Ruitenberg, M. J. / Taylor, S. M. et al. | 2012
- 1209
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The complement anaphylatoxin C3a receptor (C3aR) contributes to the inflammatory response in acute dextran sulphate sodium (DSS)-induced colitis in miceKlos, A. / Wende, E. / Laudeley, R. / Wetsel, R. A. / Glage, S. et al. | 2012
- 1210
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The novel Jagged1/CD46 interaction: A prime target for immune modulation by viruses?Sheppard, D. / Whiteman, P. / Le Friec, G. / Waddington, S. N. / Smith, R. / Melchionna, T. / Kemper, C. / McDonnell, J. M. / Handford, P. A. / Lea, S. M. et al. | 2012
- 1210
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The interference of genetic background of C57Bl/6 and A/J mice on the development of acute and chronic inflammatory response induced by ethanol: Possible contribution of C5Bavia, L. / Isaac, L. et al. | 2012
- 1210
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The human complement receptor type 2 (CR2)/CR1 fusion protein TT32, a targeted inhibitor of the classical and alternative pathway C3 convertases, prevents arthritis in active immunization and passive transfer models and acts by CR2-dependent targeting of CR1 regulatory activityHolers, M. / Banda, N. / Mehta, G. / Fridkis-Hareli, M. / Or, E. / Storek, M. / Altman, R. / Johnson, K. / Katti, S. et al. | 2012
- 1211
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The role of complement in bone healing: Fracture healing in C3 and C5-deficient miceEhrnthaller, C. M. / Huber-Lang, M. / Recknagel, S. / Bindl, R. / Redeker, S. / Rapp, A. / Gebhard, F. / Ignatius, A. et al. | 2012
- 1211
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The ratio between C4 and C4BP adsorbed from plasma predicts cytokine generation induced by artificial polymers in contact with whole bloodEngberg, A. E. / Nilsson, P. H. / Mollnes, T. E. / Rosengren-Holmberg, J. P. / Nicholls, I. A. / Nilsson, B. / Ekdahl, K. N. et al. | 2012
- 1212
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The role of the complement pathway in neuronal migration in the developing brainGorelik, A. / Reiner, O. et al. | 2012
- 1212
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The role of properdin in zymosan- and Escherichia coli-induced complement activationHarboe, M. / Garred, P. / Lindstad, J. K. / Pharo, A. / Muller, F. / Stahl, G. L. / Lambris, J. D. / Mollnes, T. E. et al. | 2012
- 1212
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The salivary scavenger and agglutinin (SALSA) binds MBL and regulates the lectin pathway of complement in solution and on surfacesReichhardt, M. P. / Loimaranta, V. / Thiel, S. / Finne, J. / Jarva, H. / Meri, S. et al. | 2012
- 1213
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The zymogen form of the catalytic region of the complement protease, C1s, is stabilized into a form unable to interact with substrates and cofactorsPike, R. N. / Perry, A. J. / Wilmann, P. G. / Duncan, R. C. / Huntington, J. A. / Whisstock, J. C. / Wijeyewickrema, L. C. et al. | 2012
- 1213
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The surface binding region of complement Factor H guides the staphylococcal Efb to cell surfaces to allow local complement inhibitionBoehm, S. / Reuter, M. / Zipfel, P. F. et al. | 2012
- 1213
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The use of 'real-time' complement analysis to differentiate atypical hemolytic uraemic syndrome from other forms of thrombotic microangiopathiesProhaszka, Z. / Szilagyi, A. / Kiss, N. / Varga, L. / Fust, G. et al. | 2012
- 1214
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Towards a new model for the C1q - Calreticulin interaction at the phagocytic synapseTouch, S. / Dimitrov, J. D. / Chouquet, A. / Halbwachs-Mecarelli, L. / Frachet, P. / Fremeaux-Bacchi, V. / Gaboriaud, C. / Roumenina, L. T. et al. | 2012
- 1214
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Thrombin induces complement production and modulates T cell responses by dendritic cells (DCs) in kidney transplant recipients with delayed graft function (DGF)Pontrelli, P. / Cariello, M. / Verrienti, R. / Tataranni, T. / Loverre, A. / Stallone, G. / Schena, F. P. / Gesualdo, L. / Grandaliano, G. et al. | 2012
- 1214
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Therapeutic application of recombinant properdin confers a significant degree of protection during Neisseria meningitidis infectionAli, Y. M. / Hayat, A. / Buchberger, A. / Kenawy, H. / Andrew, P. / Stover, C. M. / Lynch, N. / Goundis, D. / Schwaeble, W. et al. | 2012
- 1215
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VEGF-A regulates glomerular endothelial cell expression of protective complement regulators involved in the pathogenesis of atypical haemolytic uraemic syndromeKeir, L. S. / Welsh, G. I. / Coward, R. J. / Satchell, S. / Saleem, M. A. / Richards, A. et al. | 2012
- 1215
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Trypanosoma cruzi calreticulin inhibits the classical pathway of complement activation in Gallus gallusAbello, P. / Maldonado, I. / Ramirez, G. / Hidalgo, H. / Ferreira, A. / Valck, C. et al. | 2012
- 1215
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Virion-associated complement regulator CD55 is more potent than CD46 in mediating resistance of mumps virus and VSV to neutralizationJohnson, J. B. / Douglas, L. S. / Martha, A. M. / Griffith, P. D. et al. | 2012
- 1216
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Why eculizumab as treatment for EHEC-induced haemolytic uraemic syndrome?Orth, D. / Riedl, M. / Wurzner, R. et al. | 2012
- 1216
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Complement levels and complement activation in neuromyelitis opticaFust, G. / Veszeli, N. / Csuka, D. / Trauninger, A. / Rozsa, C. / Nagy, Z. / Jobbagy, Z. / Eizler, K. / Prohaszka, Z. / Varga, L. et al. | 2012
- 1217
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Species selectivity in poxviral complement regulators is dictated primarily by the charge reversal in the central complement control protein modulesYadav, N. V. / Pyara, K. / Ahmad, M. / Sahu, A. et al. | 2012
- 1217
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Peptide and protein inhibitors targeting the C3 convertase efficiently prevent surface C3 deposition and subsequent hemolysis of paroxysmal nocturnal hemoglobinuria (PNH) erythrocytesRisitano, A. M. / Ricci, P. / Pascariello, C. / Raia, M. / Schmidt, C. Q. / Qu, H. / Ricklin, D. / Del Vecchio, L. / Pane, F. / Lambris, J. D. et al. | 2012
- 1217
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The roles of the C5a receptor on the human erythroleukaemia K562 cells during the hemin-induced erythropoiesisNishiura, H. / Tetsuro, Y. et al. | 2012
- 1218
-
Type I CD20 antibodies take over the B-cell receptor for complement-dependent cytotoxicity (CDC) of malignant B cellsEngelberts, P. J. / Voorhorst, M. / Schuurman, J. / van Meerten, T. / Bakker, J. M. / Vink, T. / Mackus, W. J. / van de Winkel, J. G. / Parren, P. W. / Beurskens, F. J. et al. | 2012
- 1218
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MASP-1 is crucial for lectin pathway activation in human serum, while neither MASP-1 nor MASP-3 are required for alternative pathway functionDegn, S. E. / Jensen, L. / Hansen, A. G. / Duman, D. / Tekin, M. / Jensenius, J. C. / Thiel, S. et al. | 2012
- 1218
-
Complement system modulation as a target for treatment of arrhythmogenic right ventricular dysplasia/cardiomyopathyDavos, K. / Kostavasili, I. / Vater, A. / Mavroidis, M. et al. | 2012
- 1219
-
Development of an anti-C5/C5a antibody therapeutic that inhibits inflammatory responses via C5aR and C5L2 while maintaining MAC-dependent bactericidal functionsAn, L. L. / Colley, C. / Dobson, C. / Brennan, J. / Yang, K. / Zha, J. / Warrener, P. / Sellman, B. / Kolbeck, R. / Fung, M. et al. | 2012
- 1219
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A novel complement-mediated pathway for human TH2 induction via direct epithelial cell/T cell crosstalkFara, A. F. / Yamamoto, H. / Morton, P. / Parsons, M. / Kohl, J. / Kemper, C. et al. | 2012
- 1219
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Consumption and dysregulation of complement classical and alternative pathways in patients with streptococcus pneumoniae-associated haemolytic uremic syndromeSzilagyi, A. / Kiss, N. / Varga, L. / Prohaszka, Z. et al. | 2012
- 1220
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Complement C1q production by osteoclasts and its regulation of osteoclast developmentTeo, B. H. / Bobryshev, Y. V. / Teh, B. K. / Wong, S. H. / Lu, J. et al. | 2012
- 1220
-
C1q negatively regulates monocyte activation by IFN-alpha derived from plasmacytoid dendritic cellsLi, N. et al. | 2012
- 1220
-
CD59 deficiency is associated with chronic hemolysis and chronic inflammatory polyradiculoneuropathyMevorach, D. et al. | 2012
- 1221
-
Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanismRokstad, A. M. / Brekke, O. L. / Steinkjer, B. / Ryan, L. / Kollarikova, G. / Lambris, J. D. / Lacik, I. / Mollnes, T. E. / Espevik, T. et al. | 2012
- 1221
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Functional analyses of complement convertases using C3 and C5-depleted seraOkroj, M. / Holmquist, E. / King, B. C. / Blom, A. M. et al. | 2012
- 1221
-
Structural comparison of the C-terminal domains of factor H and CFHR-1 suggests explanation for the location of a major autoantibody epitope in autoimmune aHUSBhattacharjee, A. / Strobel, S. / Kolodziejczyk, R. / Seeberger, H. / Hyvarinen, S. / Prohaszka, Z. / Goldman, A. / Jozsi, M. / Jokiranta, S. T. et al. | 2012
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Author Index| 2012
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Omeros_Advertisement| 2012
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Editorial Board| 2012