Evaluation of load-independent inotropy in conscious sheep instrumented an axial flow left ventricular assist device (LVAD): The triple-product versus the end-diastolic pressure relationship (Englisch)
- Neue Suche nach: Kloepfer, P.
- Neue Suche nach: Del Rio, C.
- Neue Suche nach: Youngblood, B.
- Neue Suche nach: Ueyama, Y.
- Neue Suche nach: McConnell, P.
- Neue Suche nach: Kloepfer, P.
- Neue Suche nach: Del Rio, C.
- Neue Suche nach: Youngblood, B.
- Neue Suche nach: Ueyama, Y.
- Neue Suche nach: McConnell, P.
In:
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
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68
, 1
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e41
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2013
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ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:Evaluation of load-independent inotropy in conscious sheep instrumented an axial flow left ventricular assist device (LVAD): The triple-product versus the end-diastolic pressure relationship
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Beteiligte:Kloepfer, P. ( Autor:in ) / Del Rio, C. ( Autor:in ) / Youngblood, B. ( Autor:in ) / Ueyama, Y. ( Autor:in ) / McConnell, P. ( Autor:in )
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Erschienen in:JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS ; 68, 1 ; e41
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Verlag:
- Neue Suche nach: Elsevier Science B.V., Amsterdam.
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Erscheinungsdatum:01.01.2013
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Format / Umfang:e41
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ISSN:
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Medientyp:Aufsatz (Zeitschrift)
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Format:Print
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Sprache:Englisch
- Neue Suche nach: 615.9
- Weitere Informationen zu Dewey Decimal Classification
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Klassifikation:
DDC: 615.9 -
Datenquelle:
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Epileptic seizures characterization and automated detection in telemetered nonhuman primatesAuthier, S. / Bernasconi, S. / de Geyer d'Orth, T. / Pouliot, M. / Ascah, A. / Troncy, E. / Zitoun, P. et al. | 2013
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Attenuation of tactile allodynia in a rat model of neuropathic painIacono, G. / Norton, K. et al. | 2013
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What do biphasic P waves in the surface electrocardiogram mean?Vargas-Pinto, P. / Pedraza-Toscano, A. / Hamlin, R. / Carnes, C. et al. | 2013
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Effect of tethered jackets and cage size on food intake in Sprague-Dawley ratsKoehl, K. / Nolan, E. / Marsh, S. / Goodwin, E. / Krieger-Burke, T. / Bailie, M. et al. | 2013
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Electromyographic telemetry monitoring of SXN101959, a targeted secretion inhibitor (TSI) in the Sprague-Dawley ratMilano, S. / Bory, C. / Dupuis, C. / Chalencon, E. / Jones, R. / Martinez, A. et al. | 2013
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Age-related hearing loss in the C57BL/6N mouse: Time course analysis of auditory function with implications for auditory safety study designAbernathy, M. / Tapp, R. / Yoder, J. / Koch, A. / Hedke, C. / Gauvin, D. / Baird, T. et al. | 2013
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Method validation of functional observational battery assessment in rodents and nonhuman primatesLi, Y. / Niu, N. / Cai, Q. et al. | 2013
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Establishing the EEG Sleep Profile of Cocaine Withdrawal in Sprague-Dawley ratsRosado, A. / Mead, A. / DaSilva, J. et al. | 2013
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Arrhythmic effects of chronic pentamidine treatment on human cardiac stem cell electrophysiologyNumann, R. / Yue, Y. / Gibson, J. K. et al. | 2013
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Dofetilide increases load-independent indices of contractility in closed-chest anesthetized guinea pigsUeyama, Y. / del Rio, C. / Hamlin, R. et al. | 2013
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A new noninvasive biomarker-index of cardiac wavelength (l) plays an important role in drug-induced cardiac arrhythmias: Beyond QT-prolongation and torsades de pointes (TdPs)Lu, H. R. / Yan, G. X. / Gallacher, D. J. et al. | 2013
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Contractility measurements in rat heart: Comparison of isolated myocytes and Langendorff-perfused whole heartGao, B. / Qu, Y. / Fang, M. / Vargas, H. et al. | 2013
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Comparison of telemetry-derived epicardial and intravascular electrocardiogram signal characteristics in beagle dogsBaird, T. / O'Donohue, K. / Posthumus, T. / Eliel, M. / Gauvin, D. / Dalton, J. et al. | 2013
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Effect of chair-restraint on cardiac troponin levels in nonhuman primatesBarnes, R. / Harris, P. / Wisialowski, T. / Li, D. / Reagan, W. / Summers, S. / Steidl-Nichols, J. et al. | 2013
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Acute pulmonary artery hypertension in closed-chest anesthetized rats and the sustained pulmonary artery vaso-relaxation following treatment with a novel vasoactive intestinal peptideYoungblood, B. L. / del Rio, C. L. / Yeh, S. T. / Georgopoulos, L. / Arnold, S. / Hamlin, R. L. et al. | 2013
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Development of a high-throughput functional cell based l-type calcium channel assayJenkinson, S. / Bassyouni, A. / Hemkens, M. / Sun, S. / Kim, S. / Fermini, B. / Butler, P. et al. | 2013
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The voltage membrane of Chinese hamster ovary cells as a cellular tool for predicting side-effects of antimicrobial agents on mammalian cellsBoixel, C. / Martinolle, J. P. et al. | 2013
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Investigating an invertebrate model in safety pharmacology using the heartbeat of Daphnia magnaOak, S. / Park, R. / Chung, M. / Choi, J. / Kang, E. / Yang, J. / Hong, D. / Han, J. / Ra, N. / Kim, H. S. et al. | 2013
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Editorial Board| 2013
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Rat spontaneous motor activity, a sensitive first-tier screen of CNS safety for early-drug discoveryHodges, D. / Germann, U. et al. | 2013
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Use of the beam walking and drug discrimination models for determining intrinsic efficacy and selectivity of subtype selective GABA-A ligands in rodentsHsu, C. / Newman, R. / Shires, S. / Tse, K. / Warr, A. / Mead, A. / Waldron, G. et al. | 2013
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Pharmacological characterization of spontaneously contracting cardiomyocyte clusters from fish larvaeBrandenburger, M. / Mehnert, J. / Grunow, B. et al. | 2013
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Use of a guinea pig Langendorff-perfused heart model for assessing translation of cardiac sodium channel block and QRS widening in dogsRamirez, D. S. / Jenkinson, S. / Cordes, J. / Rosado, A. / Steidl-Nichols, J. / Fermini, B. et al. | 2013
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Optimisation of an integrated strategy to assess convulsion/seizure risk of novel compoundsVirginio, C. / Ugolini, A. / Siri, M. R. / Fasdelli, N. / Guidi, A. / Rostello, C. / Poffe, A. / Gerrard, P. / Corsi, M. / Pilla, M. et al. | 2013
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QT interval prolongation with a MAP kinase inhibitor following repeated dosing in telemeterized monkeysBuchanan, L. / Gill, M. / Fletcher, D. / Warner, B. / Dillon, L. / Mulraney, K. / Huang, M. / Levesque, P. et al. | 2013
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Comparison of heart rate and blood pressure values in conscious monkeys using two recording methods: Telemetry and blood pressure cuffSpeece, T. / Roush, M. / Gayheart-Walsten, P. / Love, S. / Dandekar, D. / Botchway, A. et al. | 2013
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Evaluation of intravenous (IV) solid tip ECG lead placement in telemetry implanted beaglesBills, A. J. / Mitchell, A. Z. / Taschwer, M. / Foley, C. M. / Kremer, J. J. / Wittwer, G. T. / Williams, A. M. / Osinski, M. A. et al. | 2013
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A new microchip implant for continuous body temperature recording in the ratPatterson, E. / Latour, J. / Lozano, F. / Perrault, O. / Ponchet-Lac, A. / Pradier, F. / Lemallam, M. / Fric-Bordat, M. / Martinolle, J. P. / Mazelin-Winum, L. et al. | 2013
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Electrocardiographic effects of escalating doses of cilobradine, cisapride and dofetilide in anesthetized cats: A new model for torsadogenecityPedraza-Toscano, A. / Vargas-Pinto, P. / Kijtawornrat, A. / Hamlin, R. et al. | 2013
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Assessment of electromechanical window in the anesthetized rabbit models of short QT and long QT syndromesLimprasutr, V. / Saengklub, N. / Meedech, P. / Kijtawornrat, A. et al. | 2013
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Evaluation of ion channel trafficking in human stem cell-derived cardiomyocytes for cardiotoxicity screeningAbe, Y. / Sakakura, T. / Takasuna, K. / Sanbuissho, A. / Nomura, F. / Hamada, T. / Kaneko, T. / Yasuda, K. et al. | 2013
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In vitro pharmacology and safety testing using human iPS-derived Cor.4U cardiomyocytesKettenhofen, R. / Tressat, K. / Kolossov, E. / Hebeisen, S. / Jaehne, E. / Ehlich, A. / Schwengberg, S. / Bohlen, H. et al. | 2013
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Self administration of ''weak'' reinforcers in the ratNawreen, N. / Tyszkiewicz, C. / Roberts, D. / Parker, D. / Mead, A. et al. | 2013
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Impact of noise on ECG interval measurement in nonhuman primatesBrockway, M. / Miyamoto, M. / Brockway, B. et al. | 2013
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Characterization of strain echocardiography in the ratHeyen, J. / Hemkens, M. / Blasi, E. / Buttars, S. / Deeley, B. / Theodoropoulis, C. / Butler, P. et al. | 2013
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Assessment of clinical proarrhythmic risks of bepridil, verapamil and tolterodine using the chronic atrioventricular block monkey modelHayashi, T. / Matsumoto, S. / Sakaguchi, Y. / Sakamoto, K. / Morikawa, H. / Sato, S. i. / Hombo, T. / Sugiyama, A. et al. | 2013
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Contractile behaviors of human-induced pluripotent stem cell-derived cardiomyocyte monolayers evaluated with an image-based analysis using motion vector prediction technique: A comparison with extracellular electrophysiologyHayakawa, T. / Kunihiro, T. / Ando, T. / Uno, H. / Kobayashi, S. / Matsui, E. / Yada, H. / Kanda, Y. / Kurokawa, J. / Furukawa, T. et al. | 2013
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Characterization of nonhuman primate aorta as an in vitro model for measuring vasoconstriction and vasorelaxation: Comparison to ratNottebaum, L. / Bassyouni, A. / Hemkens, M. / Jenkinson, S. / Butler, P. et al. | 2013
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Comparison of the effects of verapamil on LVP and ECG parameters between Guinea pig and rat Langendorff perfused isolated heartsDucroq, J. / Didier, H. / Salvetat, C. / Le Grand, M. et al. | 2013
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Electromyographic telemetry monitoring of SXN101959, a Targeted-Secretion Inhibitor (TSI) in the cynomolgus monkeyMilano, S. / Bory, C. / Dupuis, C. / Chalencon, E. / Jones, R. / Martinez, A. et al. | 2013
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Auditory evoked potentials: A feasibility study in telemetered cynomolgus monkeysAuthier, S. / Pouliot, M. / Schaeffer, E. / Digavalli, S. / Ascah, A. / Troncy, E. / Weed, M. et al. | 2013
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Normal electrocardiographic values in nonhuman primates in captive conditions at 2600m.a.s.lFerrer, M. / Agudelo, J. / Meneses, H. / Vargas-Pinto, P. et al. | 2013
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Influence of collection site on cochlear perilymph sample volumeAbernathy, M. / Tapp, R. / Yoder, J. / Gauvin, D. / Baird, T. et al. | 2013
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Routine production and applications of human pluripotent stem cell-derived hepatocyte-like cellsBjorquist, P. / Runeberg, K. / Steel, D. / Kuppers-Munther, B. / Edsbagge, J. et al. | 2013
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Bimodel inotropic response of dl-sotalol: Cardiovascular evaluation via pressure-volume analysis in isoflurane-anesthetized beagle dogsIshizaka, T. / Ueyama, Y. / Pedraza-Toscano, A. / Kloepfer, P. / del Rio, C. / Hamlin, R. et al. | 2013
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Use of an anesthetized guinea pig to identify proarrhythmic, inotropic, and lusitropic liabilities of test articles in safety pharmacology studyKijtawornrat, A. / Ueyama, Y. / del Rio, C. / Sawangkoon, S. / Buranakarl, C. / Chaiyabutr, N. / Hamlin, R. L. et al. | 2013
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Effect of lamotrigine, levetiracetam and topiramate on neurobehavioral parameters and oxidative stress in comparison with valproate in ratsSarangi, S. C. / Kakkar, A. K. / Kumar, R. / Gupta, Y. K. et al. | 2013
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Sensitivity, specificity, and utility of locomotor activity data generated with the kinder motor monitor system in neurotoxicity safety assessmentWalisser, J. / Elders, C. / Epping, B. / Banerjee, H. / Douglas, C. / Osinski, M. et al. | 2013
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Differentiating electrophysiological effects and cardiac safety of drugs based on in vitro electrocardiogram: A blinded validationLiu, T. / Traebert, M. / Ju, H. / Suter, W. / Guo, D. / Hoffmann, P. / Kowey, P. / Yan, G. X. et al. | 2013
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Toward quasi-in vivo from in vitro assay (II): Development of on-chip predictive cardiotoxicity assay for cardiac contraction fluctuation measurement using dual recording of electrical field potential and optical image analysisKaneko, T. / Nomura, F. / Hamada, T. / Hattori, A. / Yasuda, K. et al. | 2013
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Uniform spheres of human pluripotent stem cell-derived cardiomyocytes for extended in vitro safety pharmacology and phenotypic assaysSteel, D. / Dahlenborg, K. / Sartipy, P. et al. | 2013
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Evaluation of load-independent inotropy in conscious sheep instrumented an axial flow left ventricular assist device (LVAD): The triple-product versus the end-diastolic pressure relationshipKloepfer, P. / Del Rio, C. / Youngblood, B. / Ueyama, Y. / McConnell, P. et al. | 2013
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Evaluation of respiratory function in conscious, non-restrained cynomolgus monkey using respiratory inductive plethysmographyMaucotel, J. / El Amrani, F. / Loriot, S. / El Amrani, A. I. / Forster, R. / Legrand, J. J. et al. | 2013
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Simultaneous recording of action potentials and calcium transients from stem cell-derived cardiomyocytes: Applications for cardiotoxicity testingWhittaker, R. / Cerignoli, F. / Ingermanson, R. / Towart, R. / Gallacher, D. J. / Mercola, M. / Price, J. et al. | 2013
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Effect of artimisinin compound in experimentally induced colon carcinogenesisMedhi, B. et al. | 2013
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Influence of temperature on sensitivity of the hERG channel assayGoineau, S. / Legrand, C. / Maujeul, M. / Froget, G. et al. | 2013
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Low success rate for monocrotaline-induced pulmonary arterial hypertension in adult female nonhuman primatesPollock, Z. / Bruse, K. et al. | 2013
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Evaluation of computational modelling as a preclinical proarrhythmic safety assayMirams, G. / Beattie, K. / Cui, Y. / Luscombe, C. / Williams, G. / Gavaghan, D. / McMahon, N. et al. | 2013
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Integration of functional and biochemical biomarkers for verapamil-induced cardiac dysfunctionRoche, B. / Crumb, W. / Borders, B. / Ross, J. / Wood, B. / Jalil, A. / Henderson, K. et al. | 2013
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Influence of telemetry instrumentation on a specific set of toxicological biomarkers in cynomolgus monkeysDalton, J. / Gauvin, D. / Gesaman, J. / Hermann, E. / Denton, T. / Ward, S. / Cotey, N. / Baird, T. et al. | 2013
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Correlation of cardiovascular parameters with troponin levels following isoproteronol administration to dogsHarris, P. / Cordes, J. / Steidl-Nichols, J. / Reagan, W. / Goldstein, R. / Giovanelli, R. / Summers, S. / Wisialowski, T. et al. | 2013
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Comparison of cardiovascular parameter sensitivities in telemeterized rhesus versus cynomolgus monkeysFitzgerald, L. / Fanelli, P. / Magee, M. / Keller, W. / Reynolds, D. / Deng, M. / Grady-Styring, T. / McPherson, H. / Ferraro, J. / Garfinkel, I. et al. | 2013
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Hemodynamic data analysis - How much is enough?Douglas, C. / Jones, H. / Cheung, F. / Osinski, M. et al. | 2013
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Use of mice in cardiovascular safetyHemkens, M. / Blasi, E. / Heyen, J. / Butler, P. et al. | 2013
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The use of both anaesthetised and telemetered conscious guinea pigs in early safety pharmacology: A case study with sunitinibDelpy, E. / Garreau, M. / Infanti, F. / Loiseau, M. / La Rochelle, C. D. et al. | 2013
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Comparison of epicardial and jacketed external ECG waveforms for the detection of QT and QTc interval changesWilson, S. / Tichenor, S. / Holzgrefe, H. et al. | 2013
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An in vitro assay for assessing cardiac contractility using hiPSC-derived cardiomyocytes and cellular impedance measurementHuang, M. / Thalody, G. / Shi, H. / Levesque, P. et al. | 2013
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Proof of concept collaborative study: Evaluation of the cold-pressor response in telemetered dogs and nonhuman primatesCoffee, M. / del Rio, C. / Kearney, K. / Yohe, J. / Ueyama, Y. / Ishizaka, T. / Atterson, P. / Hamlin, R. et al. | 2013
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Toward quasi-in vivo from in vitro assay (V): Non-invasive precise purification of ventricular cells from mixture of differentiated human stem cell-derived cardiomyocytes using spot digestion of double alginate layers on a multi-electrode array chipTerazono, H. / Kim, H. / Nomura, F. / Kaneko, T. / Hamada, T. / Yasuda, K. et al. | 2013
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Human stem cell-derived cardiac myocytes as a model for identifying cardiac risk: Comparison with isolated rabbit heartQu, Y. / Gao, B. / Fang, M. / Vargas, H. et al. | 2013
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Development of a nonclinical tool for generating dynamic QT beat-to-beat cloud dataGill, M. / Lewen, G. / Buchanan, L. / Warner, W. / Levesque, P. et al. | 2013
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Evaluation of bile duct ligation-induced portal vein hypertension in telemetered ratsGuillaume, P. / Virley, D. / Bezivin, S. / Rompion, S. / Froget, G. et al. | 2013
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Ovalbumin-sensitized guinea pig cough model effective in assessing safety for aerosolized chemicalsPollock, Z. / Zhuang, J. / Zhang, C. / Xu, F. / Bruse, K. et al. | 2013
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Target related or off-target cardiovascular liabilities of receptorxagonists in telemetrized rats and knockout miceLi, J. / Thalody, G. / Flint, O. / Levesque, P. / Hennan, J. et al. | 2013
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Assessment of hERG channel function using induced pluripotent stem cell (iPS)-derived cardiomyocytesZhang, X. / Ouyang, W. / Xi, B. / Wang, X. / Xu, X. / Abassi, Y. et al. | 2013
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Morphine drug discrimination testing and substitution assessments in adult male Sprague-Dawley ratsToot, J. / Hackman, M. / Pringle, T. / Beck, M. / Atterson, P. / Stump, D. et al. | 2013
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Models based on multiple ion channel effects more predictive of cardiac riskKramer, J. / Myatt, G. / Obejero-Paz, C. / Bruening-Wright, A. / Kuryshev, Y. / Brown, A. et al. | 2013
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Simultaneous recording of ECG parameters using implanted telemetry (IT) and jacketed external telemetry (JET) in conscious, non-restrained monkeysEl Amrani, A. I. / Maucotel, J. / El Amrani, F. / Loriot, S. / Legrand, J. J. / Forster, R. et al. | 2013
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Tyrosine kinase inhibition and effects on hemodynamics, tissue mineralization, and renal phosphate regulationBlasi, E. / Yanochko, G. / Jamieson, J. / May, J. / Heyen, J. / Vitsky, A. / McHarg, A. et al. | 2013
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Applications of transgenic animals in safety pharmacologyRedfern, W. S. / Easter, A. / Ewart, L. C. / Bialecki, R. / Valentin, J. P. et al. | 2013
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Electrophysiological tools to study cardiomyocytes from single cell to organ levelHess, D. / Kraushaar, U. / Schlecht, K. / Meyer, T. / Guenther, E. et al. | 2013
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Myocardial injury associated with salbutamol administration under ischaemic myocardial stress conditions is associated with altered microRNA expressionNagra, A. / Sandhu, H. / Naz, H. / Maddock, H. / Hussain, A. et al. | 2013
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The use of the new PhysioTel(TM) Digital Telemetry Implant (DSI) for cardiovascular assessment in the Gottingen Minipig: A preliminary studyMilano, S. / Bory, C. / Dupuis, C. / Chalencon, E. / Lege, P. / Webb, A. J. / Singer, D. et al. | 2013
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Temporal profile of ovalbumin-induced airway inflammation in the Brown Norway ratMatheson, R. / Norton, K. et al. | 2013
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Reducing animal use by refining experimental paradigms and colony management in a conscious rat telemetry modelGarfinkel, I. / Hasbun-Manning, M. / Ferraro, J. / Fanelli, P. / Gerenser, P. / Deng, M. / Fitzgerald, L. / Friedrichs, G. / Salata, J. / Hoe, C. M. et al. | 2013