OR1-3: The molecular mechanism of dominantly inherited short stature caused by GH polymers (Englisch)
- Neue Suche nach: Wu, Z.
- Neue Suche nach: Junnila, R.
- Neue Suche nach: Strasburger, C. J.
- Neue Suche nach: Wu, Z.
- Neue Suche nach: Junnila, R.
- Neue Suche nach: Strasburger, C. J.
In:
Abstracts of the Seventh International Congress of the GRS and the IGF Society, October 17-20 2014, Singapore
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S5-S6
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2014
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ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:OR1-3: The molecular mechanism of dominantly inherited short stature caused by GH polymers
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Beteiligte:
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Erschienen in:GROWTH HORMONE & IGF RESEARCH ; 24 ; S5-S6
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Verlag:
- Neue Suche nach: Elsevier Science B.V., Amsterdam
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Erscheinungsdatum:01.01.2014
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Format / Umfang:S5-S6
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ISSN:
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Medientyp:Aufsatz (Zeitschrift)
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Format:Print
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Sprache:Englisch
- Neue Suche nach: 616.4
- Weitere Informationen zu Dewey Decimal Classification
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Klassifikation:
DDC: 616.4 -
Datenquelle:
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- 2
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Heat acclimation decreases the growth hormone response to acute constant-load exercise in the heatOopik, V. / Timpmann, S. / Kreegipuu, K. / Unt, E. / Tamm, M. et al. | 2014
- 10
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Discordance of IGF-1 and GH stimulation testing for altered GH secretion in obesityStanley, T. L. / Feldpausch, M. N. / Murphy, C. A. / Grinspoon, S. K. / Makimura, H. et al. | 2014
- 16
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Glucose homeostasis in adults with Prader-Willi syndrome during treatment with growth hormone: Results from a 12-month prospective studyJorgensen, A. P. / Ueland, T. / Sode-Carlsen, R. / Schreiner, T. / Rabben, K. F. / Farholt, S. / Hoybye, C. / Christiansen, J. S. / Bollerslev, J. et al. | 2014
- 22
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Impact of the growth hormone replacement on bone status in growth hormone deficient adultsKuzma, M. / Kuzmova, Z. / Zelinkova, Z. / Killinger, Z. / Vanuga, P. / Lazurova, I. / Tomkova, S. / Payer, J. et al. | 2014
- 29
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Increased genome instability and oxidative DNA damage and their association with IGF-1 levels in patients with active acromegalyBayram, F. / Bitgen, N. / Donmez-Altuntas, H. / Cakir, I. / Hamurcu, Z. / Sahin, F. / Simsek, Y. / Baskol, G. et al. | 2014
- 35
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Effects of the regulation of follistatin mRNA expression by IGF-1 in duck (Anas platyrhynchos) skeletal muscleLiu, H. / Li, X. / Sun, L. / Wang, H. / Zhang, R. / Yang, C. / Li, L. / Wang, J. / He, H. / Krumm, C. et al. | 2014
- 42
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Effects of thyroid hormone on the GH signal transduction pathwayOcaranza, P. / Lammoglia, J. J. / Iniguez, G. / Roman, R. / Cassorla, F. et al. | 2014
- 47
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Extrapituitary growth hormone synthesis in humansPerez-Ibave, D. C. / Rodriguez-Sanchez, I. P. / Garza-Rodriguez, M. d. L. / Barrera-Saldana, H. A. et al. | 2014
- 54
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Effect of milk proteins on linear growth and IGF variables in overweight adolescentsLarnkjaer, A. / Arnberg, K. / Michaelsen, K. F. / Jensen, S. M. / Molgaard, C. et al. | 2014
- 60
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Administration of growth hormone and nandrolone decanoate alters mRNA expression of the GABA"B receptor subunits as well as of the GH receptor, IGF-1, and IGF-2 in rat brainGronbladh, A. / Johansson, J. / Nyberg, F. / Hallberg, M. et al. | 2014
- 67
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GLP-1 infusion reduces IGFBP-1 serum level in humansSkov, J. / Frystyk, J. / Christiansen, J. S. et al. | 2014
- 71
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Non-functioning pituitary macroadenomas: Benefit from early growth hormone substitution after surgerySauer, N. / Flitsch, J. / Doeing, I. / Dannheim, V. / Burkhardt, T. / Aberle, J. et al. | 2014
- 76
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Insulin-like growth factor-1 (IGF-1) enhances developmental competence of cat embryos cultured singly by modulating the expression of its receptor (IGF-1R) and reducing developmental blockThongkittidilok, C. / Tharasanit, T. / Sananmuang, T. / Buarpung, S. / Techakumphu, M. et al. | 2014
- 83
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Radiometrical, hormonal and biological correlates of skeletal growth in the female rat from birth to senescencedel Pozo, E. / Janner, M. / Mackenzie, A. R. / Arampatzis, S. / Dixon, A. K. / Perrelet, R. / Ruch, W. / Lippuner, K. / Zapf, J. / Lamberts, S. W. et al. | 2014
- 89
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Exogenous IGF-1 promotes hair growth by stimulating cell proliferation and down regulating TGF-@b1 in C57BL/6 mice in vivoLi, J. / Yang, Z. / Li, Z. / Gu, L. / Wang, Y. / Sung, C. et al. | 2014
- 95
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The influence of age and exercise modality on growth hormone bioactivity in womenGordon, S. E. / Kraemer, W. J. / Looney, D. P. / Flanagan, S. D. / Comstock, B. A. / Hymer, W. C. et al. | 2014
- 104
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Corrigendum to ''Metabolic alterations in patients who develop traumatic brain injury (TBI)-induced hypopituitarism'' [Growth Horm. IGF Res. 23 (4) (2013) 109-113]Prodam, F. / Gasco, V. / Caputo, M. / Zavattaro, M. / Pagano, L. / Marzullo, P. / Belcastro, S. / Busti, A. / Perino, C. / Grottoli, S. et al. | 2014
- 105
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Association between growth hormone therapy and mortality, cancer and cardiovascular risk: Systematic review and meta-analysisDeodati, A. / Ferroli, B. B. / Cianfarani, S. et al. | 2014
- 112
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Transcriptional and epigenetic control of IGF1R gene expression: Implications in metabolism and cancerWerner, H. / Sarfstein, R. et al. | 2014
- 119
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Effects of levothyroxine on growth hormone (gh) sensitivity in children with idiopathic short statureGarcia, R. J. / Iniguez, G. / Gaete, X. / Linares, J. / Ocaranza, P. / Avila, A. / Roman, R. / Cassorla, F. et al. | 2014
- 123
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The growth hormone receptor exon 3 polymorphism is not associated with height or metabolic traits in healthy young adultsMartins, C. S. / Fernandes-Rosa, F. L. / Espineira, A. R. / de Souza, R. M. / de Castro, M. / Barbieri, M. A. / Bettiol, H. / Jorge, A. L. / Antonini, S. R. et al. | 2014
- 130
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Investigation of IGF2, Hedgehog and fusion gene expression profiles in pediatric sarcomasde Souza, R. R. / Oliveira, I. D. / del Giudice Paniago, M. / Yaoita, F. H. K. / Caran, E. M. M. / Macedo, C. R. P. D. / Petrilli, A. S. / Abib, S. d. C. V. / de Seixas Alves, M. T. / de Toledo, S. R. C. et al. | 2014
- 137
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Expression levels of insulin-like growth factors 1 and 2 in head and neck squamous cell carcinomaZhi, X. / Lamperska, K. / Golusinski, P. / Schork, N. J. / Luczewski, L. / Golusinski, W. / Masternak, M. M. et al. | 2014
- 142
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Circulating IGF-axis protein levels and their relation with levels of plasma adipocytokines and macronutrient consumption in womenBeasley, J. M. / Wedick, N. M. / Rajpathak, S. N. / Xue, X. / Holmes, M. D. / Gunter, M. J. / Wylie-Rosett, J. / Rohan, T. E. / Pollak, M. / Kaplan, R. C. et al. | 2014
- 150
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Corneal thickness in children with growth hormone deficiency: The effect of GH treatmentCiresi, A. / Morreale, R. / Radellini, S. / Cillino, S. / Giordano, C. et al. | 2014
- 155
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In memory of Francesco Maria MinutoFerone, D. / Boschetti, M. / Arvigo, M. / Fazzuoli, L. / Giusti, M. / del Monte, P. et al. | 2014
- 157
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Optimizing IGF-I for skeletal muscle therapeuticsPhilippou, A. / Barton, E. R. et al. | 2014
- 164
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IGFBP-3: A cell fate pivot in cancer and diseaseJohnson, M. A. / Firth, S. M. et al. | 2014
- 174
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Long-term effects of growth hormone replacement therapy on liver function in adult patients with growth hormone deficiencyMatsumoto, R. / Fukuoka, H. / Iguchi, G. / Nishizawa, H. / Bando, H. / Suda, K. / Takahashi, M. / Takahashi, Y. et al. | 2014
- 180
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Autosomal recessive form of isolated growth hormone deficiency is more frequent than the autosomal dominant form in a Brazilian cohortLido, A. C. V. / Franca, M. M. / Correa, F. A. / Otto, A. P. / Carvalho, L. R. / Quedas, E. P. S. / Nishi, M. Y. / Mendonca, B. B. / Arnhold, I. J. P. / Jorge, A. A. L. et al. | 2014
- 187
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IGF-I sensitivity in Silver-Russell syndrome with IGF2/H19 hypomethylationIliev, D. I. / Kannenberg, K. / Weber, K. / Binder, G. et al. | 2014
- 192
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Behavioural phenotyping of male growth hormone-releasing hormone (GHRH) knockout miceLeone, S. / Shohreh, R. / Manippa, F. / Recinella, L. / Ferrante, C. / Orlando, G. / Salvatori, R. / Vacca, M. / Brunetti, L. et al. | 2014
- 198
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Impact of moderate interval exercise versus supine rest on the pharmacokinetics and pharmacodynamic profiles of subcutaneously administered growth hormone in adult growth hormone deficient patientsJanukonyte, J. / Parkner, T. / Lauritzen, T. / Christiansen, J. S. / Frystyk, J. / Pedersen, H. S. / Laursen, T. et al. | 2014
- 205
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hGH isoform differential immunoassays applied to blood samples from athletes: Decision limits for anti-doping testingHanley, J. A. / Saarela, O. / Stephens, D. A. / Thalabard, J. C. et al. | 2014
- 216
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Circulating asymmetric dimethylarginine and lipid profile in pre-pubertal children with growth hormone deficiency: Effect of 12-month growth hormone replacement therapyDe Marco, S. / Marcovecchio, M. L. / Caniglia, D. / De Leonibus, C. / Chiarelli, F. / Mohn, A. et al. | 2014
- S1
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SY1-4: Dosing and monitoring GH treatment in Turner syndromeTanaka, T. et al. | 2014
- S2
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SY2-1: Insulin-like growth factor 2 mRNA binding proteins (IMP/IGF2BP) as mRNA safe houses in cancer and developmentChristiansen, J. / Jonson, L. / Vikesaa, J. / Hansen, T. v. O. / Nielsen, F. C. et al. | 2014
- S3
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SY2-5: The G protein estrogen receptor (GPER) is involved in IGF-I/insulin signaling in cancer cellsMaggiolini, M. et al. | 2014
- S5
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OR1-3: The molecular mechanism of dominantly inherited short stature caused by GH polymersWu, Z. / Junnila, R. / Strasburger, C. J. et al. | 2014
- S6
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OR1-6: Combination medical therapy for acromegaly: the ACROSTUDY experienceStrasburger, C. / Hey-Hadavi, J. / Akerblad, A. C. / Mattsson, A. F. / Koltowska-Haggstrom, M. / Biller, B. M. K. et al. | 2014
- S7
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OR2-2: The mitochondrial peptide humanin has fasting mimetic activity leading to suppression of circulating IGF-I and increases in IGFBP-1 levelsXiao, J. / Wan, J. / Mehta, H. / Lue, Y. H. / Jia, Y. / Swerdloff, R. / Wang, C. / Cohen, P. et al. | 2014
- S9
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OR3-1: Spatial learning, memory and signaling cross-talk: genomic and behavioral analysis in wild type versus GH modified (bGH & GHA) miceBasu, A. / Kopchick, J. J. et al. | 2014
- S10
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OR3-4: GH activated signal transducer and activator of transcription 5 is required for induction of beige fat in inguinal white adipose tissueNelson, C. N. / Ieremia, M. / Constantin, L. / List, E. O. / Kopchick, J. J. / Waters, M. J. et al. | 2014
- S12
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OR4-3: Safety and effectiveness of Increlex(R) therapy in children enrolled in the Increlex Growth Forum Database (IGFD) in Europe: 4-year interim resultsBang, P. / Polak, M. / Woelfle, J. / Sicsic, A. / Lecanuet, S. et al. | 2014
- S13
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OR4-6: The expression of insulin-like growth factor type 1 receptor (IGF1R) is increased in obese childrenRicco, R. C. / Custodio, R. J. / Atique, P. V. / Liberatore, R. D. / Ricco, R. G. / Martinelli, C. E. et al. | 2014
- S14
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OR5-3: A GH antagonist fusion with GH binding protein is biologically active, shows delayed clearance and inhibits growth in a rabbit modelWilkinson, I. / Pradhananga, S. / Sayers, J. / Artymiuk, P. / Phipps, M. / Ross, R. et al. | 2014
- S15
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OR5-6: Amplified stem/progenitor cells in a mouse model of prostate tumorigenesis induced by autocrine prolactinSackmann Sala, L. / Mosquera-Garrote, N. / Chiche, A. / Pourmir, I. / Boutillon, F. / Goffin, V. et al. | 2014
- S17
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OR6-6: Dermal fibroblast secreted IGF-I protects skin keratinocytes against ultraviolet B radiation induced damageFernandez, T. L. / Van Lonkhuyzen, D. R. / Dawson, R. / Kimlin, M. / Upton, Z. et al. | 2014
- S18
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OR7-3: Safety and efficacy results of a 6 month, randomized, multicenter trial of a novel long-acting rhGH (VRS-317) in naive to treatment, pre-pubertal children with GH deficiencyBright, G. M. / Moore, W. V. / Nguyen, H. Q. / Kletter, G. B. / Miller, B. S. / Van Meter, Q. / Humphriss, E. / Cleland, J. L. et al. | 2014
- S20
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OR7-7: Pasireotide LAR provides superior efficacy over octreotide LAR and lanreotide ATG in patients with inadequately controlled acromegaly: a phase III, multicenter, randomized study (PAOLA)Fleseriu, M. / Gadelha, M. / Bronstein, M. D. / Brue, T. / Coculescu, M. / Guitelman, M. / Pronin, V. / Raverot, G. / Shimon, I. / Fleck, J. et al. | 2014
- S21
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OR8-2: Insulin-like growth factor receptor inhibition in mammary epithelium enhances Wnt1- mediated tumors, canonical Wnt signaling and IGF-II/insulin-receptor A expressionWood, T. L. / Rota, L. M. / Albanito, L. / Shin, M. E. / Goyeneche, C. L. / Shushanov, S. / Gallagher, E. J. / Leroith, D. / Lazzarino, D. A. et al. | 2014
- S22
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OR8-5: Novel mechanisms by which Nedd4-IRS-2 complexes enhance IGF-I signals, and their roles in IGF-I action in prostate cancer cell proliferationFukushima, T. / Yoshihara, H. / Furuta, H. / Hakuno, F. / Saeki, Y. / Nakatsu, Y. / Kamata, H. / Asano, T. / Takahashi, S. I. et al. | 2014
- S23
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OR8-8: Serum IGF-I measured longitudinally during pre-school years - relation to gender, body size, and nutrition such as essential fatty acids and vitamin DDahlgren, J. et al. | 2014
- S26
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PO1-5: Socs 2 plays no major role in the increased expression of fibrotic genes in the remnant kidneyAssadi, M. H. / Abu Hilal, R. / Landau, D. / Chen, Y. / Medrano, J. / Rabkin, R. / Segev, Y. et al. | 2014
- S27
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GP2-3: The role of the insulin receptor in breast cancer progressionRostoker, R. / Abelson, S. / Bitton-Worms, K. / Genkin, I. / Ben-Shmuel, S. / Caspi, A. / Tzukerman, M. / LeRoith, D. et al. | 2014
- S28
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GP2-6: Differential effects of IGFBP-6 on migration of two ovarian cancer cell linesBach, L. / Yang, Z. et al. | 2014
- S29
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GP4-7: ProIGF-II not matureIGF-II promotes estrogen independent breast cancer growth and metastasis in a SCID and Nude mouse model: differential signallng mechanisms thru IGF and Insulin receptors and phosphorylation/activation of estrogen and progesterone receptorsJian, T. / Kalla-Singh, S. / Radhakrishnan, V. K. / De Leon, M. A. / DeLeon, D. et al. | 2014
- S30
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PO3-3: The hepatic expression of GHR and SOCS2 mRNA is increased before ovulation during the follicular phase in dairy cattleMense, K. / Meyerholz, M. / Knaack, H. / Lietzau, M. / Engelke, J. / Hoedemarker, M. / Piechotta, M. et al. | 2014
- S35
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PO3-19: IGF-1 receptor C terminal tail phosphorylation on Y1250 in cancer cellsO Shea, S. P. / Fernandez, I. / Kelly, G. M. / O' Connor, R. et al. | 2014
- S37
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GP3-2: Rosiglitazone treatment: acromegaly patients do not differ from normal type 2 diabetics in their IGFBP-1 and Insulin dynamics with euglycemic glucose clampTint, M. T. / Khoo, C. M. / Cunanan, E. / Liew, S. / Lee, K. O. et al. | 2014
- S41
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PO2-9: Growth without growth hormoneRochmah, N. / Faizi, M. et al. | 2014
- S42
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PO2-12: Development and characterization of manufacturing process of MOD-4023, a long acting human growth hormon to support clinical and commercial supplyHershkovitz, O. / Moschovich, L. / Yana Felikman, Y. / Guy, R. / Fima, E. et al. | 2014
- S44
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PO2-19: Growth hormone therapy in a child with Kearns Sayre syndrome and chronic kidney diseaseSng, A. / Loke, K. Y. / Lim, Y. / Ho, C. et al. | 2014
- S47
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GP4-2: Effects of heparin administration on the generation of IGFBP-4 fragments during PCI treatment of ST-elevation myocardial infarction patientsHjortebjerg, R. / Lindberg, S. / Jensen, J. S. / Oxvig, C. / Bjerre, M. / Frystyk, J. et al. | 2014
- S48
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GP4-5: Circulating levels of insulin-like growth factor-1(IGF-I)/insulin-like growth factor binding protein-3 (IGFBP-3) in obese patients: the state of type 2 diabetesKim, M. S. / Kim, S. Y. / Lee, D. Y. et al. | 2014
- S49
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PO4-2: Variations in growth in relation to IGF-I levels in children born very preterm and target height influences from birth to 3-years of ageKistner, A. / Hellgren, G. / Niklasson, A. / Sigurdsson, J. / Lofqvist, C. / Hellstrom, A. et al. | 2014
- S50
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PO4-6: Serum levels of IGF-I and IGFBP-1 in Indian diabetic populationTekle, M. / Vasan, S. / Brismar, K. et al. | 2014
- S51
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PO4-9: Complex tissue-specific epigenotypes in Russell Silver syndrome with 11p15 ICR1 hypomethylation: major consequences for the diagnosisAzzi, S. / Blaise, A. / Steunou, V. / Thibaud, N. / Le Bouc, Y. / Netchine, I. et al. | 2014
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OR4-5: IGF bioactivity in sera and pleural effusions from patients suspected of lung cancerEspelund, U. / Hjortebjerg, R. / Folkersen, B. / Rasmussen, T. R. / Oxvig, C. / Frystyk, J. et al. | 2014
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OR6-1: Dicarba modification of insulin peptides results in lower mitogenic activity signaled via IGF-1R and IR than insulinOng, S. C. / van Lierop, B. / Delaine, C. / Andrikopoulos, S. / Robinson, A. / Forbes, B. et al. | 2014
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OR8-7: Insulin like growth factor-II (IGF-II) regulates mitochondrial phenotype, metabolism and DNA content to prevent apoptosis and to increase energy production efficiency promoting a more aggressive and chemoresistant breast cancer diseaseRadhakrishnan, V. K. / DeLeon, D. et al. | 2014
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GP2-1: IGF-I ameliorates hepatic fibrosis in mouse models of nonalcoholic steatohepatitis and cirrhosis via inhibiting the activity or hepatic stellate cellsNishizawa, H. / Iguchi, G. / Fukuoka, H. / Takahashi, M. / Suda, K. / Bando, H. / Matsumoto, R. / Takahashi, Y. et al. | 2014
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GP2-4: Insulin-like growth factor binding protein (IGFBP)-1 and its RGD domain: favorable in vivo actions in glucose regulationHaywood, N. / Yuldasheva, N. / Aziz, A. / Smith, J. / Cordell, P. / Kearney, M. / Wheatcroft, S. et al. | 2014
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PO3-6: Serum concentrations of IGF-I and IGF-II proceed in a reciprocal manner during a physiological cycle and maternal IGFBP-4 concentration was lower in pregnant than in not pregnant dairy heifers during early pregnancyMeyerholz, M. / Mense, K. / Linden, M. / Knaack, H. / Wirthgen, E. / Hoeflich, A. / Lietzau, M. / Richard, C. / Raliou, M. / Sandra, O. et al. | 2014
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PO3-10: Constitutive IRS1 expression causes cell competition, leading to defect in myogenic differentiationHakuno, F. / Yoneyama, Y. / Ozoe, A. / Takahashi, S. I. et al. | 2014
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GP1-5: Presurgical somatostatin analogue versus direct surgery for newly-diagnosed acromegaly patients: a systematic review and meta-analysis, assessing clinical evidence using the GRADE systemNunes, V. S. / Correa, J. M. / Puga, M. E. / Silva, E. M. / Boguszewski, C. L. et al. | 2014
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GP3-6: Mixed effects PK/PD modelling of NNC0195-0092 - a noncovalent albumin binding growth hormone derivative in the hypophysectomised ratThygesen, P. / Agerso, H. / Fels, J. J. / Johansen, N. L. et al. | 2014
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PO2-4: Pregnancy in acromegaly patients treated with pegvisomantVan der Lely, A. J. / Gomez, R. / Heissler, J. F. / Akerblad, A. C. / Jonsson, P. / Camacho-Hubner, C. / Koltowska-Haggstrom, M. et al. | 2014
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PO2-7: Assessing the impact of storage flexibility on daily life for patients and caregivers taking/administering growth hormone (GH)Kappelgaard, A. M. / Metzinger, C. P. / Signer-Romero, K. / Schnabel, D. et al. | 2014
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PO4-4: Cerebrospinal fluid and serum levels of growth hormone (GH), insulin-like-growth factor-I (IGF-1), insulin-like growth factor binding protein -3 (IGFBP-3) and ghrelin in patients with bacterial and tuberculous meningitisAkinci, A. / Gungor, S. / Yucel, G. / Ozerol, H. I. et al. | 2014
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PO5-1: Clinical relevance of serum prolactin level in perimenopausal women with metabolic syndromePchelin, I. / Hudiakova, N. / Shishkin, A. et al. | 2014
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OR2-5: Linkage of reproductive development, fat metabolism and lifespan by the RGD-motif of IGFBP-2 in female transgenic miceHoeflich, A. / Spitschak, M. / Ohde, D. / Schindler, N. / Brenmoehl, J. / Langhammer, M. / Bielohuby, M. / Renner-Muller, I. / Wanke, R. / Metzger, F. et al. | 2014
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OR3-6: Loss of acyl-ghrelin signalling in male ghrelin-O-acyltransferase knock-out mice results in reduced pulsatile growth hormone secretion and a derangement of GH pulse patternXie, T. Y. / Ngo, S. T. / Veldhuis, J. D. / Jeffery, P. L. / Chopin, L. K. / Tschop, M. / Trolle, V. / Epelbaum, J. / Steyn, F. J. / Chen, C. et al. | 2014
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OR8-6: The anti-IGF signaling agents increase the efficacy of Trabectedin in Ewing sarcomaGarofalo, C. / Amaral, A. T. / Uboldi, S. / Mancarella, C. / Frapolli, R. / Manara, M. C. / Ordonez, J. L. / Belfiore, A. / Picci, P. / Hassan, B. et al. | 2014
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PO1-1: Analysis of chimeric mice using growth hormone receptor gene disrupted (GHRKO) derived bone-marrow to investigate the role of GH signaling in the infiltration of proinflammatory macrophages in adipose tissueHerpy, J. / Okada, S. / Benencia, F. / Kopchick, J. J. et al. | 2014
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PO3-4: IGF-1-regulated PDLIM2 protein is required for epithelial to mesenchymal transition (EMT) and transcription factor stabilityCox, O. T. / Bowe, R. A. / Tresse, E. / O'Connor, R. et al. | 2014
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PO3-11: Porphyra yezoensis peptide stimulates the proliferation of IEC-6 cells by activating the insulin-like growth factor-I receptor signaling pathwayNam, T. J. / Lee, M. K. / Kim, I. H. / Choi, Y. H. et al. | 2014
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PO3-17: Hypermethylation and hypomethylation of IGF-II DMRO (Insulin like growth factors-II Differentially Methylated Region) correlated to increased or decreased expression of IGF-II in breast cancer cells and paired breast tissues of African American and Caucasian breast cancer patientsRadhakrishnan, V. K. / De Leon, M. A. / DeLeon, D. et al. | 2014
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GP1-6: Metabolic requirements to sustain NEFA and glucose homeostasis overrides the role of growth hormone in promoting rapid linear growth in hyperphagic MC4RKO miceTan, H. Y. / Huang, L. / Veldhuis, J. D. / Cowley, M. / Steyn, F. J. / Chen, C. et al. | 2014
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PO2-6: Autocrine human growth hormone (hGH) promotes metabolic reprogramming in breast cancer cells to adapt to available glucoseBanerjee, A. / Pandey, V. K. / Lau, A. Y. C. / Lobie, P. E. et al. | 2014
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PO2-26: Pharmacokinetic (PK) and pharmacodynamic (PD) modeling of MOD-4023 (a long-acting hGH-CTP) in adults and growth hormone (GH)-deficient childrenFisher, D. / Koren, R. / Amitzi, L. / Hershkovitz, O. / Hart, G. et al. | 2014
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GP4-6: Effects of GH/IGF-I axis on retinal vascular morphology: retinal vascular morphology in Laron syndromeSekeroglu, H. T. / Kadayifcilar, S. / Kasim, B. / Arslan, U. / Ozon, Z. A. et al. | 2014
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OR2-6: Cyclic glycine-proline is a regulator that dynamically controls IGF-1 homeostasis through altering IGF-1 binding to IGFBP3Guan, J. / Gluckman, P. / Yang, P. / Wen, J. / Krissansen, G. / Sun, K. / Zhou, Y. / McMahon, C. / Shorten, P. / Wake, G. et al. | 2014
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OR5-1: Mechanism of activation of JAK2 by growth hormoneWaters, M. J. / Brooks, A. J. et al. | 2014
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OR7-6: Safety and efficacy of ARX201: six month dose-ranging study of a novel long-acting pegylated growth hormone in young adults with growth hormone deficiencyRacz, K. / Coculescu, M. / Olyinik, V. / Popa, M. / Popovic, V. / Radiuk, K. / Senatorova, A. S. / Vlasenko, M. V. / Norman, T. / Juhasz, M. et al. | 2014
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PO3-14: Activated STAT3 as a possible resistance mechanism to the anti-tumour effects of an anti-IGF-II neutralising antibody in hepatocellular carcinomaGreenall, S. A. / Johns, T. G. / Adams, T. E. et al. | 2014
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PO2-15: Insulin tolerance test and GHRH plus arginine in the reassessment of pituitary function at adult height achievementDi Iorgi, N. / Salerno, M. C. / Cappa, M. / Loche, S. / Radetti, G. / Capaldo, D. / Allegri, A. / Napoli, F. / Calcagno, A. / Iovovich, O. B. et al. | 2014
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GP4-4: SGA short stature bearing with a novel nonsense mutation (p.W1219X) in the IGF1R geneFujimoto, M. / Kawashima, Y. / Hamajima, T. / Miyahara, N. / Nishimura, R. / Hanaki, K. / Kanzaki, S. et al. | 2014
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PO4-5: Insulin like growth factor-1 therapy in five patients with growth hormone insensitivityErsoy, B. / Ozhan, B. / Kizilay, D. / Kiremitci, S. et al. | 2014
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PO4-7: Functional selectivity of the insulin-like growth factor type 1 receptor (IGF-1R) signaling: therapeutic implications for cancer treatmentGirnita, L. / Crudden, C. J. / Suleymanova, N. / Oprea, I. / Worrall, C. / Girnita, A. et al. | 2014
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PO5-2: Serum prolactin level in chronic kidney diseaseVasilkova, O. / Szhmailik, M. / Zekenova, K. / Mokhort, T. et al. | 2014
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SY1-3: Dosing and Monitoring GH treatment in children born SGALeger, J. et al. | 2014
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OR1-4: Successful GH treatment for severe growth failure in pediatric patients with anorexia nervosaFjellestad-Paulsen, A. / Bargiacchi, A. / Doyen, C. / Raverdy, C. / Carel, J. C. / Le Heuzey, M. F. / Leger, J. et al. | 2014
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OR2-3: The Cardin-Weintraub Motif present in IGFBP-2 is required for growth and function of the mouse brainSchindler, N. / Mayer, J. / Kirschstein, T. / Saenger, S. / Gimsa, U. / Brenmoehl, J. / Ohde, D. / Zeissler, A. / Russo, V. / Metzger, F. et al. | 2014
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OR3-2: GH enhances spine density in amygdalar neuronsGisabella, B. / Brophy, J. / Goosens, K. A. et al. | 2014
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OR7-5: Safety, tolerability, pharmacokinetics and pharmacodynamics of TV-1106, a new long-acting treatment for growth hormone deficiencyCohenBarack, O. / Sakov, A. / Rasamoelisolo, M. / Bassan, M. / Brown, K. / Spiegelstein, O. et al. | 2014
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GP1-3: Role of growth hormone (GH) signaling pathways in the development of atherosclerosisIshikawa, M. / Toyomura, J. / Kuboki, K. / Morita, T. / Tominaga, N. / Hirose, T. / Minami, S. / Yoshino, G. et al. | 2014
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PO2-10: Growth hormone treatment: case studies in Dr Soetomo HospitalRochmah, N. / Faizi, M. et al. | 2014
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PO2-17: Soluble alpha-Klotho and vitamin D in acromegalyBolanowski, M. / Jawiarczyk-Przybylowska, A. / Kolackov, K. et al. | 2014
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SY1-5: Growth hormone replacement in adult growth hormone deficiency: long-term efficacy and safetyJohannsson, G. et al. | 2014
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SY1-6: Growth hormone and sarcopenia - future aspectsThorner, M. et al. | 2014
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OR1-1: GH treatment modulates mortality in adult onset GH deficiency and a discordant socio-economic status is apparentStochholm, K. / Berglund, A. / Gravholt, C. / Christiansen, J. S. et al. | 2014
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OR2-1: Impaired mTORC1 activity up-regulates IGFBP-1 synthesis during dietary protein restrictionTakenaka, A. / Hino, M. / Takeuchi, K. / Takahashi, S. I. et al. | 2014
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OR4-2: Growth hormone is a more potent growth stimulating hormone than IGF-I: clinical perspectiveLaron, Z. / Kauli, R. / Iluz, M. / Samuel, K. / Silbergeld, A. et al. | 2014
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OR5-5: Autocrine hGH stimulated miRNA 96-182-183 cluster promotes epithelial-mesenchymal transition and invasion in breast cancerZhang, W. / Qian, P. / Zhang, X. / Zhang, M. / Wang, H. / Wu, M. / Kong, X. / Tan, S. / Ding, K. / Perry, J. K. et al. | 2014
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PO3-5: Developing predictive determinants of IGF/INS targeted therapies in ovarian cancer patient tumors and primary tumorgraftsBecker, M. / Hou, X. / Haluska, P. et al. | 2014
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PO3-7: Growth hormone addition to medium in HepG2 cell culture: influence on IGF-I and IGF-II productionKnaack, H. / Mense, K. / Piechotta, M. et al. | 2014
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GP3-3: The diagnostic accuracy of pegvisomant-primed glucagon stimulation test (PV-GST) compared to insulin tolerance (ITT) and glucagon stimulation (GST) tests in evaluating adult growth hormone (GH) reserveYuen, K. C. J. / Frystyk, J. / Rhoads, S. A. / Legg, S. E. / Bidlingmaier, M. et al. | 2014
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PO3-8: Understanding and targeting the IGFBP-3/IGFBP-3R system in obesity related disorders: IGFBP-3R agonists as preventive and therapeutic interventions for obesity-induced IR and T2DMCai, Q. / Oh, Y. et al. | 2014
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PO2-25: Assessment of hydration based on bioelectrical impedance analysis (BIA) and arm muscle area (AMA) in treatment-naive adult patients with growth hormone deficiency (GHD)Jorgensen, J. O. L. / Tonnes Pedersen, B. / Pournara, E. / Hoybye, C. et al. | 2014
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SY1-2: Dosing and Monitoring GH Treatment in GH Deficient ChildrenCohen, P. et al. | 2014
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GP1-1: Growth hormone targets expression of specific lipolytic genes to promote lipolysis of white adipose tissueLaw, Y. Y. / Romero, C. / Radovick, S. et al. | 2014
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GP1-2: Autocrine human growth hormone suppression of E-CADHERIN via p44/42 MAPK promotes epithelial-tomesenchymal transition (EMT) of colorectal carcinoma cellsWang, J. / Wu, Z. / Pandey, V. / Chen, Y. / Zhu, T. / Lobie, P. et al. | 2014
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PO2-20: Safety evaluation of long-term recombinant growth hormone (rGH) treatment in paediatric patients: interim analysis of NordiNet(R) International Outcome Study (IOS)Savendahl, L. / Pournara, E. / Tonnes Pedersen, B. / Blankenstein, O. et al. | 2014
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PO4-1: Alpha-fetoprotein at birth: an early marker of circulating IGF-I in preterm infantsKistner, A. / Hellgren, G. / Hansen Pupp, I. / Ley, D. / Lofqvist, C. / Hellstrom, A. et al. | 2014
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OR1-2: Impairment of anaerobic capacity in adults with growth hormone deficiencyChikani, V. / Cuneo, R. / Hickman, I. / Ho, K. et al. | 2014
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OR7-4: A phase 2, six-month dose-response study to investigate TransCon hGH, a long-acting hGH, in treatment naive children with idiopathic growth hormone deficiency (IGHD)Chatelain, P. / Malievsky, O. / Radziuk, K. / Elsedfy, H. / Mikhailova, E. / Beckert, M. et al. | 2014
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OR8-1: Insulin receptor substrate (IRS)-1 interacts with protein arginine methyltransferase 5 (PRMT5), emerging as a novel regulator of alternative pre-mRNA splicingOzoe, A. / Narita, Y. / Fukushima, T. / Kataoka, N. / Ito, A. / Yoshida, M. / Chida, K. / Asano, T. / Hakuno, F. / Takahashi, S. I. et al. | 2014
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OR8-4: A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignanciesSun, J. / Li, W. / Sun, Y. / Wang, H. / Cui, J. / Wang, G. / Wei, Z. / Hoffman, A. / Hu, J. et al. | 2014
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GP2-2: The deubiquitinating enzyme, USP9X positively regulates insulin-like growth factor (IGF)-dependent cell growth by inhibition of degradation of IGF-I receptor (IGF-IR) and insulin receptor substrate (IRS)-2 in prostate cancer cellsFuruta, H. / Yoshihara, H. / Fukushima, T. / Saeki, Y. S. / Ito, A. / Worrall, C. / Girnita, L. / Tanaka, K. / Yoshida, M. / Asano, T. et al. | 2014
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GP4-1: Loss of PI 3-kinase-binding protein PI3KAP/XB130 suppresses thyroid function and induces enlargement of thyroid glands in miceYamanaka, D. / Hakuno, F. / Minami, S. / Hashimoto, K. / Suzuki, K. / Chida, K. / Takahashi, S. I. et al. | 2014
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PO3-13: ADLib(R) system: a versatile antibody discovery platformHashimoto, S. / Uchiki, T. / Moriyama, S. / Sasakura, Y. / Tsuji, T. / Konakahara, S. / Nakazaki, Y. / Hani, T. / Asagoshi, K. / Sawada, A. et al. | 2014
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GP3-5: Thyroid hormone activation regulates exercise induced growth hormone releaseIgnacio, D. L. / Silvestre, D. H. S. / Cavalcanti-de-Albuquerque, J. P. / Neto, R. A. L. / Ferreira, A. C. C. / Carvalho, D. P. / Werneck-de-Castro, J. P. S. et al. | 2014
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PO2-2: An evaluation of the safety and usability of FlexPro(R) 30 mg/3 mL, for the delivery of Norditropin(R) in patients requiring growth hormone (GH) therapyKappelgaard, A. M. / Wen, Y. / Klinck, R. / Qvist, M. / Fuchs, G. S. et al. | 2014
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PO2-8: Specific measurement of human growth hormone oligomers in blood and its possible clinical applicationWu, Z. / Strasburger, C. J. et al. | 2014
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PO2-14: Genetic markers of insulin resistance are associated with growth hormone response in short SGA children - the North European SGA study (NESGAS)Jensen, R. B. / Thankamony, A. / Day, F. / Kirk, J. / Donaldson, M. / Ivarsson, S. A. / Soder, O. / Roche, E. / Hoey, H. / Juul, A. et al. | 2014
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PO2-24: Elevated spontaneous trough GH levels are associated with Lipoprotein (a) in short prepubertal children with high waist-hip ratioDecker, R. / Andersson, B. / Kristrom, B. / Nygren, A. / Albertsson-Wikland, K. et al. | 2014
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GP4-3: Epigenetic analyses of the insulin-like growth factor binding protein 1 gene in diabetes and diabetic nephropathyGu, T. / Gu, H. F. / Falhammar, H. / Hilding, A. / Sjoholm, L. K. / Ostenson, C. G. / Ekstrom, T. J. / Brismar, K. et al. | 2014
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OR1-5: Short-term low dose GH therapy improves insulin sensitivity but does not affect cortisol metabolism and ectopic fat accumulation in GH deficient adultsYuen, K. C. J. / Frystyk, J. / Klopfenstein, B. J. / Rooney, W. D. / Purnell, J. Q. et al. | 2014
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OR5-2: Rabbits are a suitable animal model for the pre-clinical development of growth hormone agonists and antagonistsBielohuby, M. / Zarkesh-Esfahani, S. H. / Manolopoulou, J. / Khorasgani, M. T. / Aghili, Z. S. / Wilkinson, I. R. / Ross, R. J. / Bidlingmaier, M. et al. | 2014
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OR6-5: Sexual dimorphism of insulin like growth factor I in exerciseMunive Herrera, V. A. / Torres Aleman, I. et al. | 2014
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PO3-1: Molecular, biochemical, histological, and phylogenetic characterizations of insulin-like peptides and insulin/insulinlike growth factor (IGF)-I receptors in rotifersOzaki, Y. / Kaneko, G. / Hakuno, F. / Takahashi, S. I. / Mark Welch, D. et al. | 2014
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PO2-22: Usability and safety of FlexPro(R) PenMate(R), a growth hormone (GH) injection system, in patients, caregivers and healthcare professionalsWen, Y. / Korsholm, C. N. / Klinck, R. / Kappelgaard, A. M. et al. | 2014
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PO4-8: Subclinical hypothyroidism is associated with low IGF-I levels and decreased growth velocityBellini, H. / Maciel, L. M. / Custodio, R. J. / Milani, S. S. / Paula, M. S. / Antonini, S. R. / Liberatori, R. D. / Martinelli, C. E. et al. | 2014
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SY1-7: Abuse of growth hormoneStrasburger, C. J. et al. | 2014
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OR2-4: Exogenous administration of protease-resistant, non matrixbinding IGFBP-2 inhibits tumour growth in a murine model of breast cancerSoh, C. L. / McNeil, K. / Owczarek, C. M. / Hardy, M. / Fabri, L. J. / Pearse, M. / Delaine, C. A. / Forbes, B. E. et al. | 2014
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PO3-9: Effects of endurance training on somatic growth in a rat model of chronic kidney disease (CKD)Troib, A. / Guterman, M. / Landau, D. / Rabkin, R. / Segev, Y. et al. | 2014
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PO3-16: Altered mouse adipose tissue IGF-1 expression influences glucose controlTrost, J. / Alcaniz Rolli, J. / Brockmann, G. et al. | 2014
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PO3-18: Lipopolysaccharide (LPS) treatment increased the protein levels of GKAP42 (42-kDa cGMP-dependent protein kinase anchoring protein) followed by inhibition of insulinmediated glucose transporter (GLUT) 4 translocation to the plasma membrane and glucose uptake in adipocytesYu, B. C. / Ando, Y. / Obata, Y. / Takenaka, A. / Chida, K. / Hakuno, F. / Takahashi, S. I. et al. | 2014
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GP3-1: Growth hormone (GH) replacement has a beneficial effect on glycosylated haemoglobin (HbA1c) levels in adult patients with GH deficiency (GHD) enrolled in the NordiNet(R) International Outcome Study (IOS)Weber, M. M. / Tonnes Pedersen, B. / Pournara, E. / Christiansen, J. S. et al. | 2014
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PO2-13: Human growth hormone and human prolactin possess autocrine roles in hepatocellular carcinomaZhang, M. / Kong, X. / Wu, Z. / Yan, Y. / Pandey, V. / Wu, W. / Lu, X. / Zhang, W. / Li, G. / Tan, S. et al. | 2014
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SY2-4: IGFBP-2 in Cancer: From The Matrix to The Inside JobRusso, V. C. et al. | 2014
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OR4-1: Randomised controlled clinical trial contrasting current GH doses with dose based on IGF-I titration in children born small for gestational age (NESGAS)Jensen, R. B. / Thankamony, A. / O'Connell, S. M. / Kirk, J. / Donaldson, M. / Ivarsson, S. A. / Soder, O. / Roche, E. / Hoey, H. / Dunger, D. B. et al. | 2014
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OR5-4: The choice of growth hormone receptor signalling pathway determines longevityChhabra, Y. / Nelson, C. N. / Plescher, M. / Brooks, T. / Waters, M. J. et al. | 2014
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OR6-2: IRS-1 promotes embryonic growth of zebrafish through IGF-IR signal-dependent and -independent mechanisms in response to developmental stages and environmental oxygen availabilityKamei, H. / Sawada, R. / Yoneyama, Y. / Hakuno, F. / Shimizu, T. / Takahashi, S. I. et al. | 2014
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OR6-4: Sustained IGF-II production is necessary for adult neurogenesisZiegler, A. N. / Testai, J. / Constancia, M. / Sandovici, I. / Wood, T. L. / Levison, S. W. et al. | 2014
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OR7-1: A reversible albumin-binding GH derivative possesses a promising once-weekly treatment profile and is well tolerated in adult subjects with growth hormone deficiencyHojby Rasmussen, M. / Janukonyte, J. / Klose, M. / Marina, D. / Tanvig, M. / Nielsen, L. F. / Hoybye, C. / Andersen, M. / Feldt-Rasmussen, U. / Sandahl Christiansen, J. et al. | 2014
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OR7-2: The MOD-4023 story; a long acting GH from proof of concepts in animal models to growth hormone deficient populations clinical studies (adults and pediatric )Hart, G. / Hershkovitz, O. / Koren, R. / Amitzi, L. / Fima, E. et al. | 2014
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OR7-8: A phase II randomised, open-label, parallelgroup study of the safety, tolerability, pharmacokinetics and efficacy of two subcutaneous dosing regimens of ATL1103 in adult patients with acromegalyTrainer, P. J. / Newell-Price, J. / Ayuk, J. / Aylwin, S. / Drake, W. M. / Rees, A. / Chanson, P. / Brue, T. / Webb, S. M. / Fajardo, C. et al. | 2014
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GP2-7: The IGF/IGFR pathway regulates axial patterning during early neural development in mammalTakata, N. / Sakakura, E. / Kasukawa, T. / Eiraku, M. / Sasai, Y. et al. | 2014
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GP3-4: Discordance of post-surgical nadir GH during OGTT and serum IGF-I levels in patients with acromegalyFukuda, I. / Hizuka, N. / Muraoka, T. / Amano, K. / Kawamata, T. / Okada, Y. / Ichihara, A. et al. | 2014
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PO2-1: The pathogenesis of anti-PIT-1 antibody syndrome - the involvement of PIT-1-reactive cytotoxic T lymphocytesBando, H. / Iguchi, G. / Fukuoka, H. / Matsumoto, R. / Suda, K. / Nishizawa, H. / Takahashi, M. / Tojo, K. / Takahashi, Y. et al. | 2014
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PO2-3: Multiple doses of a reversible albumin-binding growth hormone derivative demonstrate no differences in PK and PD between Japanese and non-Asian subjectsHojby Rasmussen, M. / Olsen, M. W. B. / Alifrangis, L. / Klim, S. / Suntum, M. et al. | 2014
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PO2-5: Severe headache relieved by short-acting somatostatin analogue in a patient with Acromegaly resistant to longacting somatostatin analoguesHoybye, C. et al. | 2014
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PO2-16: IGF-1 as nutritional markerKim, J. H. / Lee, J. et al. | 2014
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PO4-3: Serum levels of insulin-like growth factor I (IGF-I) and insulin-like growth factor binding protein 3 (IGFBP-3) in women with cervical cancerCho, D. H. / Kim, M. S. et al. | 2014
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SY2-2: The IRS proteins: determinants of IGF-1R signaling and tumor metabolismShaw, L. / Landis, J. / Zhu, S. / Janusis, J. / Mercado-Matos, J. et al. | 2014
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GP2-5: Hyperglycaemia induces chemo-resistance of breast cancer cells via regulating IGFBP-2/oestrogen receptor (ERa) interactions: role of ERa phosphorylationZeng, L. / Holly, J. M. / Arshad, A. / Bahl, A. / Hathwar, S. / Perks, C. M. et al. | 2014
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PO2-21: Growth hormone deficiency amongst nasopharyngeal cancer survivorsRatnasingam, J. / Karim, N. / Paramasivam, S. / Ibrahim, L. / Lim, L. L. / Jalaludin, A. / Tan, A. / Vethakkan, S. / Chan, S. P. et al. | 2014
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PO2-23: Growth and puberty of children with congenital isolated growth hormone deficiencySmuel, K. / Kauli, R. / Laron, Z. et al. | 2014
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OR3-3: Liver-specific (LiGHRKO) and fat-specific (FaGHRKO) growth hormone receptor gene disrupted mice demonstrate paradoxical longevity and provide evidence for GH stimulated liver/adipose tissue-crosstalkList, E. O. / Berryman, D. E. / Jara, A. / Ikeno, Y. / Miller, R. A. / Kopchick, J. J. et al. | 2014
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OR3-5: NPY neurons as a critical hypothalamic node for the control of GH release relative to food intakeHuang, L. / Tan, H. / Fogarty, M. / Stark, R. / Andrews, Z. / Veldhuis, J. / Herzog, H. / Chen, C. / Steyn, F. et al. | 2014
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OR4-4: The causal role of IGFs and IGFBPs in prostate cancer: a Mendelian randomization studyBonilla, C. / Rowlands, M. A. / Lewis, S. J. / Palmer, T. / Gaunt, T. R. / Davey Smith, G. / Gunnell, D. / Donovan, J. L. / Hamdy, F. C. / Neal, D. E. et al. | 2014
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OR6-3: Early postnatal nutritional programming of growth involves GHRH neurons axon growth stimulation by leptin & IGF-IDecourtye, L. / Mire, E. / Clemessy, M. / Heurtier, V. / Godefroy, D. / Cong, R. / Ledent, T. / Robinson, I. / Reaux-Le Goazigo, A. / Mollard, P. et al. | 2014
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OR8-3: Role of deubiquitinase USP7 in signalling through IGF-1RWorrall, C. / Suleymanova, N. / Yoshihara, H. / Hakuno, F. / Takahashi, S. I. / Girnita, A. / Girnita, L. et al. | 2014
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PO3-2: Modulation of IGFBP1 protein expression by metforminAnsurudeen, I. / Brismar, K. et al. | 2014
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PO3-12: Balancing the IGF-1R-Mdm2-p53 axis as novel therapeutic strategy in skin melanomaGirnita, A. / Worall, C. / Candrea, E. / Takahashi, S. I. / Girnita, L. et al. | 2014
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PO3-15: Regulation of IGF-1 at the transcription level by IGFBP-1Ansurudeen, I. / Brismar, K. et al. | 2014
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GP1-4: Mortality in patients with non-functioning pituitary adenoma with and without growth hormone replacement therapy. A case-controlled study in more than 400 patientsTrimpou, P. / Johannsson, G. / Andersson, E. / Nilsson, A. G. / Olsson, D. S. et al. | 2014
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PO2-11: Evidence for truncated somatostatin receptor 5 modulation of therapy response to somatostatin analogues in two patients with acromegaly and severe headacheMarina, D. / Burman, P. / Klose, M. / Casar-Borota, O. / Luque, R. M. / Castano, J. P. / Feldt-Rasmussen, U. et al. | 2014