Correlation of in vitro screening technologies for secondary pharmacodynamic assessment (Englisch)
- Neue Suche nach: Armstrong, D.
- Neue Suche nach: Bright, J.
- Neue Suche nach: Jolas, T.
- Neue Suche nach: Migeon, J.
- Neue Suche nach: Rolf, M.
- Neue Suche nach: Rosenbrier-Ribero, L.
- Neue Suche nach: Valentin, J. P.
- Neue Suche nach: Bowes, J.
- Neue Suche nach: Armstrong, D.
- Neue Suche nach: Bright, J.
- Neue Suche nach: Jolas, T.
- Neue Suche nach: Migeon, J.
- Neue Suche nach: Rolf, M.
- Neue Suche nach: Rosenbrier-Ribero, L.
- Neue Suche nach: Valentin, J. P.
- Neue Suche nach: Bowes, J.
In:
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
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70
, 3
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320-
;
2014
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ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:Correlation of in vitro screening technologies for secondary pharmacodynamic assessment
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Beteiligte:Armstrong, D. ( Autor:in ) / Bright, J. ( Autor:in ) / Jolas, T. ( Autor:in ) / Migeon, J. ( Autor:in ) / Rolf, M. ( Autor:in ) / Rosenbrier-Ribero, L. ( Autor:in ) / Valentin, J. P. ( Autor:in ) / Bowes, J. ( Autor:in )
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Erschienen in:JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS ; 70, 3 ; 320-
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Verlag:
- Neue Suche nach: Elsevier Science B.V., Amsterdam.
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Erscheinungsdatum:01.01.2014
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Format / Umfang:1 pages
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ISSN:
-
Medientyp:Aufsatz (Zeitschrift)
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Format:Print
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Sprache:Englisch
- Neue Suche nach: 615.9
- Weitere Informationen zu Dewey Decimal Classification
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Klassifikation:
DDC: 615.9 -
Datenquelle:
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Software based arrhythmia detection in telemetered animalsVormberge, T. / Hoffmann, M. / Ruppert, S. et al. | 2014
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Comparative analysis of methodologies assessing QT risk in large animal modelsKearney, K. / Landis, K. / Atterson, P. et al. | 2014
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Improving small animal cardiovascular telemetry using next generation implantable technologyKaiser, R. / Lindquist, R. / Regalia, D. / Doyle, J. et al. | 2014
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Influence of chronic telemetry instrumentation on toxicological biomarkers and pathology in cynomolgus monkeys: A comprehensive one-year reviewMay, J. / Dalton, J. / Aulbach, A. / Amuzie, C. / Gauvin, D. / Gesaman, J. / Hermann, E. / Denton, T. / Posthumus, T. / Cotey, N. et al. | 2014
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Pimobendan, etilefrine, moxifloxacin, and esketamine as reference compounds to validate the DSI Physiotel Digital System in cynomolgus monkeysNiehoff, M. / Sternberg, J. / Niggemann, B. / Sarazan, D. et al. | 2014
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Demonstration of simultaneous automated blood sample collection and recording of radiotelemetered physiologic measurements in caged unrestrained cynomolgus macaquesKruzich, P. J. / Hopper, L. D. / Kurtz, S. L. / Swaab, M. / Singer, D. / Sarazan, R. D. et al. | 2014
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Thioridazine-induced QTc prolongation: Minipig is more sensitive than the dogRoberts, S. / Jenni, R. / Waiz, D. / Staudner, H. / Sanders, M. / Greiter-Wilke, A. et al. | 2014
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JET-BP (Jacketed External Telemetry with Blood Pressure) — A comparison of statistical analysis methods with JET-BP data sets in the dogPriestley, P. / Marshall, B. / Ashcroft-Hawley, K. et al. | 2014
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Validation of video-tEEG model in rat to assess convulsion/seizure risk of novel compoundsRostello, C. / Poffe, A. / Pilla, M. / Gerrard, P. / Fasdelli, N. et al. | 2014
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Recording of intracranial pressure in conscious rats via telemetryGuild, S. J. / Budgett, D. / Stehlin, E. / Barrett, C. / Simonetta, G. / Malpas, S. et al. | 2014
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A preload and lusitropy corrected dP/dtmax-derived index of contractility: Evaluation in telemetered beagle dogs treated with amrinoneYoungblood, B. / Kloepfer, P. / Ueyama, Y. / George, R. / Sutayatram, S. / Hardy, R. / Gallacher, M. / Ottinger, S. / Hamlin, R. / del Rio, C. et al. | 2014
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Evaluation of cardiac electrophysiology (ECG), heart rate and index of cardiac electrophysiological balance (iCEB) during basal condition in awake telemetered and anesthetized guinea pigsUrmaliya, V. / Verrelst, J. / Daems, H. / Lu, H. R. / Teisman, A. / Gallacher, D. J. et al. | 2014
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Quantified electroencephalography (QEEG) in safety pharmacologyEsneault, E. / Peyon, G. / Babin, D. / Castagné, V. / Virley, D. / Froget, G. et al. | 2014
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Comparison of HDO® (high definition oscillometry), a novel noninvasive technology for arterial blood pressure measurement, to a direct invasive method using radiotelemetric equipment in awake healthy catsEgner, B. / King, J. N. / Laveissiere, A. / Martel, E. et al. | 2014
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Electrocardiographic changes during induced hemorrhagic shock in anesthetized dogs: Predictors of the severity of shock-induced metabolic imbalancesGeorge, R. / del Rio, C. / Youngblood, B. / Ueyama, Y. / Kloepfer, P. / Muir, W. / Robert, H. et al. | 2014
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Characterization of an anesthetized dog model of simulated angina for detection of drug-induced conduction slowing and ventricular proarrhythmiaDamiano, B. P. / Van der Linde, H. / Van Beuren, B. / Somers, Y. / Teisman, A. / Gallacher, D. J. et al. | 2014
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The usefulness of echocardiography in exploring of predictive biomarkers for rosiglitazone-induced cardiac hypertrophyKazusa, K. / Shirakawa, T. / Kida, S. / Watanabe, Y. / Sasaki, D. / Ohata, T. et al. | 2014
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Relationship between dP/dtmax, QA interval, contractility index, and preload recruitable stroke work in anesthetized guinea pigsKijtawornrat, A. / Ueyama, Y. / del Rio, C. / Sawangkoon, S. / Buranakarl, C. / Chaiyabutr, N. / Hamlin, R. L. et al. | 2014
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A platform for cardiotoxicity screening based on manufacturable Stretchable Micro-Electrode Arrays (SMEAs)Pakazad, S. K. / van de Stolpe, A. / Dekker, R. et al. | 2014
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The index of cardiac electrophysiological balance (iCEB) as a biomarker for drug-induced effects on repolarization in anesthetized guinea-pigs, dogs and minipigsLoenders, B. / van der Linde, H. / Lu, H. R. / Teisman, A. / Gallacher, D. et al. | 2014
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De-risking the effect of CGRP receptor antagonists on coronary blood flow and systemic hemodynamics in nonhuman primatesRegan, C. / Detwiler, T. / Salvatore, C. / Lynch, J. et al. | 2014
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Prolongation of QT interval related to hERG mRNA expression in rabbits with right ventricular hypertrophyMeedech, P. / Limprasutr, V. / Saengklub, N. / Kalandakanond-Thongsong, S. / Kijtawornrat, A. / Hamlin, R. et al. | 2014
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Assessment of electrocardiograph in a minipig utilizing jacketed telemetryKirouac, A. / Norton, K. et al. | 2014
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Comparison of indices of left ventricular inotrope and lusitrope in isoflurane-anesthetized, closed chest, dogsSaengklub, N. / del Rio, C. / Kijtawornrat, A. et al. | 2014
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Will hydroxypropyl-β-cyclodextrin modify the hemodynamic response of your drug candidate in the anesthetized dog?Rosseels, M. L. / Delaunois, A. G. / Hanon, E. / Guillaume, P. J. / Martin, F. d. / van den Dobbelsteen, D. J. et al. | 2014
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Evaluation of a novel method utilizing Physioflow®, a signal morphology-based impedance cardiography, to non-invasively measure cardiac output in the restrained, conscious beagleRossman, E. / Payseur, J. / Rigney, J. / Turner, S. / Wu, X. / Lewis, J. / Murphy, D. et al. | 2014
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The electromechanical window: Not superior to QT as a surrogate parameter for risk of dofetilide-induced Torsade de Pointes in the anesthetized canine complete atrioventricular block modelStams, T. / Bourgonje, V. / Beekman, J. / Schoenmakers, M. / van der Nagel, R. / Oosterhoff, P. / van Opstal, J. / Vos, M. et al. | 2014
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Methods to assess drug-induced endothelial dysfunctionSkinner, M. / Philp, K. / Bales, J. / Woodhouse, N. / Harmer, A. / Valentin, J. P. et al. | 2014
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Autonomic system impairment in hemodynamic responses to orthostatic hypotension in ratsSalvail, D. / Bouchard, A. et al. | 2014
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Effect of changes in heart rate on load-independent contractility: Chronotropic-inotropism in anesthetized guinea pigsUeyama, Y. / Geroge, R. S. / del Rio, C. L. / Hamlin, R. L. et al. | 2014
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The index of cardiac electrophysiological balance: A new noninvasive biomarker in anesthetized dogs and the effect of changes in heart rate and body temperaturevan der Linde, H. / Van Deuren, B. / Somers, Y. / Loenders, B. / Lu, H. R. / Teisman, A. / Gallacher, D. J. et al. | 2014
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Gender sensitivity and specificity during cardiovascular de-risking in anesthetized guinea pigs and its clinical translationUrmaliya, V. / Verrelst, J. / Daems, H. / Teisman, A. / Gallacher, D. J. et al. | 2014
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Assessment of target involvement in drug-induced seizures using knockout mouse hippocampal neurons and multielectrode arraysBurnett, E. / Kwagh, J. / Psaltis, G. / Sun, L. / Shi, H. / Flint, O. / Levesque, P. et al. | 2014
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Vernakalant is devoid of proarrhythmic effects in the cAVB dogVarkevisser, R. / Tieland, R. / Beekman, J. / van der Heyden, M. / Vos, M. et al. | 2014
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Validation of FOB in two rat strains: Crl:CD(SD) vs Crl:WI(Han) ratsPilla, M. / Guidi, A. / Pavoni, V. / Cunego, L. / Gerrard, P. / Fasdelli, N. et al. | 2014
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Anticonvulsant actions of SKa-31 in pilocarpine treated chronic epileptic ratsRaza, M. L. / Heinemann, U. et al. | 2014
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Use of the Allay™ restraint collar to facilitate the measurement of ventilation in conscious ratsHouse, A. / Shafer, R. / Shemesh, Y. / Lomask, J. / Chapman, R. W. / Mauser, P. J. et al. | 2014
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Evaluation of a feline model for ototoxicity testingTapp, R. / Abernathy, M. / Yoder, J. / Wilson, B. / Dolan, D. / Gauvin, D. / Baird, T. et al. | 2014
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Toward quasi-in vivo from in vitro assay (IV): Fabrication of direction-controlled artificial neuronal networks using agarose-microetching method and single-cell-electrodes for quantitative evaluation of neuropsychiatric disordersTerazono, H. / Kim, H. / Hattori, A. / Nomura, F. / Hamada, T. / Yasuda, K. et al. | 2014
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Identification and resolution of drug related problems (DRPs) in respiratory medicine patients at a tertiary care hospitalIqbal, J. / Geer, I. / Koul, P. et al. | 2014
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Respiratory safety pharmacology — Current practice and future directionsMurphy, D. et al. | 2014
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Evaluation of iPrecio — Dual Channel pump: A safety pharmacology study case in the Gottingen MinipigBory, C. / Lege, P. / Chalencon, E. / Milano, S. et al. | 2014
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Safety pharmacology vital organ functions compared in two different Wistar rat strainsHoffmann, M. / Prelle, K. / Himmel, H. et al. | 2014
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The use of temperature loggers in laboratory animal experiments for pathogenesis research and evaluation of prevention and treatment of infectious diseasesvan den Brand, J. / Helgadóttir, B. / Stittelaar, K. / Bjarnason, s. / de Waal, L. / de Swart, R. / Kuiken, T. / Osterhaus, A. et al. | 2014
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Evaluation of iPrecio — Dual Channel pump: A safety pharmacology study case in the Cynomolgus MonkeyBory, C. / Lege, P. / Chalencon, E. / Milano, S. / Gilbert, K. / Koeppel, F. et al. | 2014
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Developing a medium throughput cellular assay to quantify modulators of contractility using human induced pluripotent stem cell-derived cardiomyocytesScott, C. W. / Zhang, X. / Peters, M. F. / Abassi, Y. A. / Abi-Gerges, N. et al. | 2014
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The mouse induced Pluripotent Stem cell-derived cardiomyocytes: Detection of pro-arrhythmia, chronotropy, inotropy and cardiac cell death by RTCA cardio measurementColomar, A. / Haen, L. / Loiodice, S. / Toussaint, G. / Atienzar, F. et al. | 2014
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Quantifying contractile forces in engineered human cardiac microtissuesvan Spreeuwel, A. C. / Braam, S. R. / Bastiaens, A. J. / Chen, C. S. / Bouten, C. V. et al. | 2014
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Enhanced maturation of stem cell-derived cardiomyocytesBraam, S. / Towart, R. et al. | 2014
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Multi-lineage differentiation of a panel of human iPS cell lines from healthy donors: A step towards in vitro modelling of human genetic diversityDanielsson, S. / Holmgren, G. / Dahlenborg, K. / Asplund, A. / Van Giezen, M. / Pradip, A. / Aspegren, A. / Larsson, S. / Noaksson, K. / Kuppers, B. et al. | 2014
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Adverse cardiotoxic side effects on contractility analyzed with impedance technology in a human stem cell-derived 3D modelSteel, D. / Thomas, U. / Danielsson, S. / Dahlenborg, K. / Stoelzle, S. / Schwarzenberger, T. / Guinot, D. / Fertig, N. / Sartipy, P. et al. | 2014
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Comparative assessment of different types of human stem cell-derived cardiomyocytes for predictive electrophysiological safety screening using microelectrode arrays (MEA)Kraushaar, U. / Hess, D. / Lu, H. R. / Gallacher, D. J. / Guenther, E. et al. | 2014
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Automated patch clamp and an impedance-based assay system with cardiomyocytes derived from pluripotent stem cells as a predictive tool for cardiac safety pharmacologyStölzle, S. / Rubenchik, O. / Tenelsen, J. / Metzger, P. / Schwarzenberger, T. / Thomas, U. / Kettenhofen, R. et al. | 2014
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Detection of Ca++ transients in iPS-derived cardiomyocytes: An HTS-ready method of measuring cardiomyocyte functionKettenhofen, R. / Licher, T. / Sauerborn, S. / Hisada, S. / Niedereichholz, T. / Schwengberg, S. et al. | 2014
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Discrimination power of optically recorded action potentials in cardiomyocytes derived from human induced pluripotent stem cellsSmith, G. / Cooper, J. / Hortigon-Vinagre, M. / Ghouri, I. / Craig, M. A. / Anson, B. / Wallis, R. et al. | 2014
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Human cardiomyocytes derived from iPS cells: Characterization and assessment of drug-induced changes on action potentials, ion currents, extracellular field potentials and impedance signalsKettenhofen, R. / Numann, R. / Gibson, J. K. / Hebeisen, S. / Duenbostell, A. / Rubenchik, O. / Tenelsen, J. / Metzger, P. / Bohlen, H. et al. | 2014
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Field potential measurement using iPS cell-derived cardiomyocytes for the prediction of cardiotoxicity in vitroSakakibara, M. / Kitamura, T. / Otsuki, M. / Bunai, F. / Minami, D. / Fujisaki, Y. / Sekijima, M. / Osada, T. et al. | 2014
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Advancing cardiac safety with a “thorough preclinical QT Study” using low-impedance microelectrode arrays and human stem cell-derived cardiomyocytesNavarrete, E. / Liang, P. / Lan, F. / Sanchez-Freire, V. / Simmons, C. / Gong, T. / Patlolla, B. / Trujillo, M. / Jiko, H. / Bers, D. et al. | 2014
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Optimizing rate correction of field potential duration, a biomarker for QT risk assessmentLuerman, G. / Obejero-Paz, C. / Kramer, J. / Brown, A. / Bruening-Wright, A. et al. | 2014
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Force–frequency analysis of contraction using a novel laser-speckle contrast techniques in iPS-derived cardiomyocytes, Repro Cardio2™Sawada, K. / Ojima, A. / Taniguchi, T. / Miyamoto, N. / Iwai, H. / Sugiyama, N. / Kataoka, T. / Yoshida, S. et al. | 2014
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Responses of iCell hIPSC-derived cardiomyocytes to cardiac modulators in the xCELLigence cardio label free impedance platformBalasubramanian, B. / Lis, T. / Wu, Z. / Gretzula, C. / Gregan, I. / Uebele, V. / Fox, S. / Lagrutta, A. / Imredy, J. / Sannajust, F. et al. | 2014
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Lack of clear effects of QT-shortening drugs in human pluripotent stem cell-derived cardiomyocytes: A mystery that still needs to be solvedLu, H. R. / Rohrbacher, J. / Hermans, A. N. / Gallacher, D. J. et al. | 2014
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Optimization and pharmacological characterization of iCell cardiomyocytes for electrophysiological assessment in a multi-electrode extracellular recording systemSawada, K. / Taniguchi, T. / Ojima, A. / Yoshinaga, T. / Miyamoto, N. et al. | 2014
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Accurate prediction of drug induced liver injury using stem cell based approachesSzkolnicka, D. / Farnworth, S. / Lucendo-Villarin, B. / Storck, C. / Zhou, W. / Iredale, J. / Flint, O. / Hay, D. et al. | 2014
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Efficient and cost-effective batch analysis of multi-electrode array (MEA) data from human iPS cardiomyocytes using Intelligent Waveform Service (IWS)Thomas, T. / Harris, K. / Sridhar, A. / Cui, Y. et al. | 2014
- 357
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Specialized preclinical safety pharmacology studies for stimulant abuse therapeuticsAppel, N. / Acri, J. / McCann, D. et al. | 2014
- 357
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Examining the predictive capabilities of cardiomyocytes derived from human induced pluripotent stem cells (hiPS-CMs) for arrhythmogenic liability testing in a high throughput assayWhittaker, R. / Cerignoli, F. / Vega, R. / Towart, R. / Lu, H. R. / Gallacher, D. / Price, J. et al. | 2014
- 357
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Examining the predictive capabilities of cardiomyocytes derived from human embryonic stem cells derived cardiomyocytes (hES-CMS) for arrhythmogenic liability testing in a high throughput assayWhittaker, R. / Cerignoli, F. / Vega, R. / Towart, R. / Lu, H. R. / Gallacher, D. / Price, J. et al. | 2014
- 357
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Assessment of in vivo safety of IVIG products: Evaluation of sensitivity and specificity in a modified venous stasis rabbit modelBiernat, M. / Laurent, C. / Bouchard, A. / Salvail, D. et al. | 2014
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Use of gastric emptying and emesis models to improve the assessment of upper gastrointestinal tract motilityGuillaume, P. / Goineau, S. / Bezivin, S. / Eveilleaux, E. / Froget, G. et al. | 2014
- 358
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Use of cultured human renal tubular epithelial cells to predict nephrotoxicity of leading compoundsYan, C. / Liao, M. / Ding, R. / Dong, Y. / Han, G. / Shi, C. / Wu, C. et al. | 2014
- IFC
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Editorial Board| 2014