Inhibition of P‑Glycoprotein Does Not Increase the Efficacy of Proteasome Inhibitors in Multiple Myeloma Cells (Englisch)
- Neue Suche nach: Mynott, Rachel L.
- Neue Suche nach: Wallington-Beddoe, Craig T.
- Weitere Informationen zu Wallington-Beddoe, Craig T.:
- https://orcid.org/0000-0002-7457-5937
- Neue Suche nach: Mynott, Rachel L.
- Neue Suche nach: Wallington-Beddoe, Craig T.
- Weitere Informationen zu Wallington-Beddoe, Craig T.:
- https://orcid.org/0000-0002-7457-5937
In:
ACS Pharmacology & Translational Science
;
4
, 2
;
713-729
;
2021
-
ISSN:
- Aufsatz (Zeitschrift) / Elektronische Ressource
-
Titel:Inhibition of P‑Glycoprotein Does Not Increase the Efficacy of Proteasome Inhibitors in Multiple Myeloma Cells
-
Weitere Titelangaben:ACS Pharmacol. Transl. Sci.
-
Beteiligte:Mynott, Rachel L. ( Autor:in ) / Wallington-Beddoe, Craig T. ( Autor:in )
-
Erschienen in:ACS Pharmacology & Translational Science ; 4, 2 ; 713-729
-
Verlag:
- Neue Suche nach: American Chemical Society
-
Erscheinungsdatum:09.04.2021
-
ISSN:
-
Coden:
-
DOI:
-
Medientyp:Aufsatz (Zeitschrift)
-
Format:Elektronische Ressource
-
Sprache:Englisch
-
Schlagwörter:
-
Datenquelle:
Inhaltsverzeichnis – Band 4, Ausgabe 2
Zeige alle Jahrgänge und Ausgaben
Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
- 413
-
The Promise of Psychedelic ScienceOlson, David E. et al. | 2021
- 416
-
Combining Psychedelic and Mindfulness Interventions: Synergies to Inform Clinical PracticePayne, Jake E / Chambers, Richard / Liknaitzky, Paul et al. | 2021
- 424
-
Predicting Reactions to Psychedelic Drugs: A Systematic Review of States and Traits Related to Acute Drug EffectsAday, Jacob S. / Davis, Alan K. / Mitzkovitz, Cayla M. / Bloesch, Emily K. / Davoli, Christopher C. et al. | 2021
- 436
-
On the Relationship between Classic Psychedelics and Suicidality: A Systematic ReviewZeifman, Richard J. / Singhal, Nikhita / Breslow, Leah / Weissman, Cory R. et al. | 2021
- 452
-
Transient Stimulation with Psychoplastogens Is Sufficient to Initiate Neuronal GrowthLy, Calvin / Greb, Alexandra C. / Vargas, Maxemiliano V. / Duim, Whitney C. / Grodzki, Ana Cristina G. / Lein, Pamela J. / Olson, David E. et al. | 2021
- 461
-
Low Doses of LSD Acutely Increase BDNF Blood Plasma Levels in Healthy VolunteersHutten, Nadia R. P. W. / Mason, Natasha L. / Dolder, Patrick C. / Theunissen, Eef L. / Holze, Friederike / Liechti, Matthias E. / Varghese, Nimmy / Eckert, Anne / Feilding, Amanda / Ramaekers, Johannes G. et al. | 2021
- 467
-
Discriminative Stimulus Effects of Substituted Tryptamines in RatsGatch, Michael B. / Hoch, Adam / Carbonaro, Theresa M. et al. | 2021
- 472
-
Set and Setting: A Randomized Study of Different Musical Genres in Supporting Psychedelic TherapyStrickland, Justin C. / Garcia-Romeu, Albert / Johnson, Matthew W. et al. | 2021
- 479
-
Serotonin 2A Receptor (5-HT2AR) Activation by 25H-NBOMe Positional Isomers: In Vitro Functional Evaluation and Molecular DockingPottie, Eline / Kupriyanova, Olga V. / Brandt, Asher L. / Laprairie, Robert B. / Shevyrin, Vadim A. / Stove, Christophe P. et al. | 2021
- 488
-
Structure–Activity Relationship Analysis of Psychedelics in a Rat Model of Asthma Reveals the Anti-Inflammatory PharmacophoreFlanagan, Thomas W. / Billac, Gerald B. / Landry, Alexus N. / Sebastian, Melaine N. / Cormier, Stephania A. / Nichols, Charles D. et al. | 2021
- 503
-
Tropane-Based Ibogaine Analog Rescues Folding-Deficient Serotonin and Dopamine TransportersBhat, Shreyas / Guthrie, Daryl A. / Kasture, Ameya / El-Kasaby, Ali / Cao, Jianjing / Bonifazi, Alessandro / Ku, Therese / Giancola, JoLynn B. / Hummel, Thomas / Freissmuth, Michael et al. | 2021
- 517
-
EEG Gamma Band Alterations and REM-like Traits Underpin the Acute Effect of the Atypical Psychedelic Ibogaine in the RatGonzález, Joaquín / Cavelli, Matias / Castro-Zaballa, Santiago / Mondino, Alejandra / Tort, Adriano B. L. / Rubido, Nicolás / Carrera, Ignacio / Torterolo, Pablo et al. | 2021
- 526
-
Psilocybin-Assisted Group Therapy and Attachment: Observed Reduction in Attachment Anxiety and Influences of Attachment Insecurity on the Psilocybin ExperienceStauffer, Christopher S / Anderson, Brian T / Ortigo, Kile M. / Woolley, Joshua et al. | 2021
- 533
-
Investigation of the Structure–Activity Relationships of Psilocybin AnaloguesKlein, Adam K. / Chatha, Muhammad / Laskowski, Lauren J. / Anderson, Emilie I. / Brandt, Simon D. / Chapman, Stephen J. / McCorvy, John D. / Halberstadt, Adam L. et al. | 2021
- 543
-
Naturalistic Use of Mescaline Is Associated with Self-Reported Psychiatric Improvements and Enduring Positive Life ChangesAgin-Liebes, Gabrielle / Haas, Trevor F. / Lancelotta, Rafael / Uthaug, Malin V. / Ramaekers, Johannes G. / Davis, Alan K. et al. | 2021
- 553
-
Acute and Sustained Reductions in Loss of Meaning and Suicidal Ideation Following Psilocybin-Assisted Psychotherapy for Psychiatric and Existential Distress in Life-Threatening CancerRoss, Stephen / Agin-Liebes, Gabrielle / Lo, Sharon / Zeifman, Richard J. / Ghazal, Leila / Benville, Julia / Franco Corso, Silvia / Bjerre Real, Christian / Guss, Jeffrey / Bossis, Anthony et al. | 2021
- 563
-
The Subjective Effects of Psychedelics May Not Be Necessary for Their Enduring Therapeutic EffectsOlson, David E. et al. | 2021
- 568
-
The Subjective Effects of Psychedelics Are Necessary for Their Enduring Therapeutic EffectsYaden, David B. / Griffiths, Roland R. et al. | 2021
- 573
-
Ethical Concerns about Psilocybin Intellectual PropertyGerber, Konstantin / Flores, Inti García / Ruiz, Angela Christina / Ali, Ismail / Ginsberg, Natalie Lyla / Schenberg, Eduardo E. et al. | 2021
- 578
-
Consciousness, Religion, and Gurus: Pitfalls of Psychedelic MedicineJohnson, Matthew W. et al. | 2021
- 582
-
Pyruvate Dehydrogenase as a Therapeutic Target for Nonalcoholic Fatty Liver DiseaseSaed, Christina T. / Tabatabaei Dakhili, Seyed Amirhossein / Ussher, John R. et al. | 2021
- 589
-
Ultrasound-Responsive Nanocarriers in Cancer Treatment: A ReviewAwad, Nahid S. / Paul, Vinod / AlSawaftah, Nour M. / ter Haar, Gail / Allen, Theresa M. / Pitt, William G. / Husseini, Ghaleb A. et al. | 2021
- 613
-
Repurposing Quinoline and Artemisinin Antimalarials as Therapeutics for SARS-CoV-2: Rationale and ImplicationsFirestone, Tessa M. / Oyewole, Opeoluwa O. / Reid, St Patrick / Ng, Caroline L. et al. | 2021
- 624
-
A Review of Small-Molecule Inhibitors of One-Carbon Enzymes: SHMT2 and MTHFD2 in the SpotlightCuthbertson, Christine R. / Arabzada, Zahra / Bankhead, Armand / Kyani, Armita / Neamati, Nouri et al. | 2021
- 647
-
From Simple Mouth Cavities to Complex Oral Mucosal DisordersCurcuminoids as a Promising Therapeutic ApproachGirisa, Sosmitha / Kumar, Aviral / Rana, Varsha / Parama, Dey / Daimary, Uzini Devi / Warnakulasuriya, Saman / Kumar, Alan Prem / Kunnumakkara, Ajaikumar B. et al. | 2021
- 666
-
Therapeutic Opportunities of Targeting Allosteric Binding Sites on the Calcium-Sensing ReceptorDiao, Jiayin / DeBono, Aaron / Josephs, Tracy M. / Bourke, Jane E. / Capuano, Ben / Gregory, Karen J. / Leach, Katie et al. | 2021
- 680
-
Adenosine Kinase Expression Determines DNA Methylation in Cancer Cell LinesWahba, Amir E. / Fedele, Denise / Gebril, Hoda / AlHarfoush, Enmar / Toti, Kiran S. / Jacobson, Kenneth A. / Boison, Detlev et al. | 2021
- 687
-
Assessment of Phenylboronic Acid Nitrogen Mustards as Potent and Selective Drug Candidates for Triple-Negative Breast CancerFan, Heli / Zaman, Muhammad Asad Uz / Chen, Wenbing / Ali, Taufeeque / Campbell, Anahit / Zhang, Qi / Setu, Nurul Islam / Saxon, Eron / Zahn, Nicolas M. / Benko, Anna M. et al. | 2021
- 703
-
Silencing of Oncogenic KRAS by Mutant-Selective Small Interfering RNAPapke, Bjoern / Azam, Salma H. / Feng, Anne Y. / Gutierrez-Ford, Christina / Huggins, Hayden / Pallan, Pradeep S. / Van Swearingen, Amanda E. D. / Egli, Martin / Cox, Adrienne D. / Der, Channing J. et al. | 2021
- 713
-
Inhibition of P‑Glycoprotein Does Not Increase the Efficacy of Proteasome Inhibitors in Multiple Myeloma CellsMynott, Rachel L. / Wallington-Beddoe, Craig T. et al. | 2021
- 730
-
Comparative Activity and Off-Target Effects in Cells of the CHK1 Inhibitors MK-8776, SRA737, and LY2606368Ditano, Jennifer P. / Eastman, Alan et al. | 2021
- 744
-
Small Molecule Targeting of Oxysterol-Binding Protein (OSBP)-Related Protein 4 and OSBP Inhibits Ovarian Cancer Cell Proliferation in Monolayer and Spheroid Cell ModelsBensen, Ryan C. / Gunay, Gokhan / Finneran, Matthew C. / Jhingan, Isha / Acar, Handan / Burgett, Anthony W. G. et al. | 2021
- 757
-
Peripherally Selective CB1 Receptor Antagonist Improves Symptoms of Metabolic Syndrome in MiceKhan, Nayaab / Laudermilk, Lucas / Ware, Jalen / Rosa, Taylor / Mathews, Kelly / Gay, Elaine / Amato, George / Maitra, Rangan et al. | 2021
- 765
-
Selective Endocannabinoid Reuptake Inhibitor WOBE437 Reduces Disease Progression in a Mouse Model of Multiple SclerosisReynoso-Moreno, Ines / Tietz, Silvia / Vallini, Erika / Engelhardt, Britta / Gertsch, Jürg / Chicca, Andrea et al. | 2021
- 780
-
Identification of Small-Molecule Inhibitors of Human Inositol Hexakisphosphate Kinases by High-Throughput ScreeningLiao, Gangling / Ye, Wenjuan / Heitmann, Tyler / Ernst, Glen / DePasquale, Michael / Xu, Laiyi / Wormald, Michael / Hu, Xin / Ferrer, Marc / Harmel, Robert K. et al. | 2021
- 790
-
Biosimilar or Not: Physicochemical and Biological Characterization of MabThera and Its Two Biosimilar CandidatesWang, Hong / Wu, Linping / Wang, Can / Xu, Jin / Yin, Hongrui / Guo, Huaizu / Zheng, Luxia / Shao, Hong / Chen, Gang et al. | 2021
- 802
-
Highly Efficient Water-Soluble Photosensitizer Based on Chlorin: Synthesis, Characterization, and Evaluation for Photodynamic TherapySun, Yue / Geng, Xiaorui / Wang, Yihui / Su, Xiaomin / Han, Ruyin / Wang, Jiangyue / Li, Xinyan / Wang, Pan / Zhang, Kun / Wang, Xiaobing et al. | 2021
- 813
-
Proadrenomedullin N‑Terminal 20 Peptides (PAMPs) Are Agonists of the Chemokine Scavenger Receptor ACKR3/CXCR7Meyrath, Max / Palmer, Christie B. / Reynders, Nathan / Vanderplasschen, Alain / Ollert, Markus / Bouvier, Michel / Szpakowska, Martyna / Chevigné, Andy et al. | 2021
- 824
-
Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted In Vivo ChemistryStéen, E. Johanna L. / Jørgensen, Jesper T. / Denk, Christoph / Battisti, Umberto M. / Nørregaard, Kamilla / Edem, Patricia E. / Bratteby, Klas / Shalgunov, Vladimir / Wilkovitsch, Martin / Svatunek, Dennis et al. | 2021
- 834
-
Exploring the Cytotoxic Effects of the Extracts and Bioactive Triterpenoids from Dillenia indica against Oral Squamous Cell Carcinoma: A Scientific Interpretation and Validation of Indigenous KnowledgeAswathy, Maniyamma / Banik, Kishore / Parama, Dey / Sasikumar, Parameswaran / Harsha, Choudhary / Joseph, Anuja Gracy / Sherin, Daisy R. / Thanathu, Manojkumar K. / Kunnumakkara, Ajaikumar B. / Vasu, Radhakrishnan Kokkuvayil et al. | 2021
- 848
-
Sterol Biosynthesis Inhibition in Pregnant Women Taking Prescription MedicationsGenaro-Mattos, Thiago C. / Klingelsmith, Korinne B. / Allen, Luke B. / Anderson, Allison / Tallman, Keri A. / Porter, Ned A. / Korade, Zeljka / Mirnics, Károly et al. | 2021
- 858
-
Sustained Release GLP‑1 Agonist PT320 Delays Disease Progression in a Mouse Model of Parkinson’s DiseaseWang, Vicki / Kuo, Tung-Tai / Huang, Eagle Yi-Kung / Ma, Kuo-Hsing / Chou, Yu-Ching / Fu, Zhao-Yang / Lai, Li-Wen / Jung, Jin / Choi, Hoi-II / Choi, Doo-Sup et al. | 2021
- 870
-
Tissue-Specific Proteomics Analysis of Anti-COVID-19 Nucleoside and Nucleotide Prodrug-Activating Enzymes Provides Insights into the Optimization of Prodrug Design and Pharmacotherapy StrategyLi, Jiapeng / Liu, Shuhan / Shi, Jian / Wang, Xinwen / Xue, Yanling / Zhu, Hao-Jie et al. | 2021
- 888
-
Macrocyclic Gq Protein Inhibitors FR900359 and/or YM-254890–Fit for Translation?Schlegel, Jonathan G. / Tahoun, Mariam / Seidinger, Alexander / Voss, Jan H. / Kuschak, Markus / Kehraus, Stefan / Schneider, Marion / Matthey, Michaela / Fleischmann, Bernd K. / König, Gabriele M. et al. | 2021
- 898
-
Synergistic Inhibition of SARS-CoV‑2 Replication Using Disulfiram/Ebselen and RemdesivirChen, Ting / Fei, Cheng-Yin / Chen, Yi-Ping / Sargsyan, Karen / Chang, Chun-Ping / Yuan, Hanna S. / Lim, Carmay et al. | 2021
- 908
-
Design, Synthesis, Pharmacokinetics, and Biodistribution of a Series of Bone-Targeting EP4 Receptor Agonist Prodrugs for Treatment of Osteoporosis and Other Bone ConditionsThévenin, Marion / Chen, Gang / Kantham, Srinivas / Sun, Chunxiang / Glogauer, Michael / Young, Robert N. et al. | 2021
- 926
-
Target-Driven Design of a Coumarinyl Chalcone Scaffold Based Novel EF2 Kinase Inhibitor Suppresses Breast Cancer Growth In VivoComert Onder, Ferah / Kahraman, Nermin / Bellur Atici, Esen / Cagir, Ali / Kandemir, Hakan / Tatar, Gizem / Taskin Tok, Tugba / Kara, Goknur / Karliga, Bekir / Durdagi, Serdar et al. | 2021
- 941
-
General Stepwise Approach to Optimize a TR-FRET Assay for Characterizing the BRD/PROTAC/CRBN Ternary ComplexLin, Wenwei / Chen, Taosheng et al. | 2021
- 953
-
Lipophilicity Determines Routes of Uptake and Clearance, and Toxicity of an Alpha-Particle-Emitting Peptide Receptor RadiotherapyTafreshi, Narges K. / Kil, HyunJoo / Pandya, Darpan N. / Tichacek, Christopher J. / Doligalski, Michael L. / Budzevich, Mikalai M. / Delva, Nella C. / Langsen, Michael L. / Vallas, John A. / Boulware, David C. et al. | 2021
- 966
-
Differential Therapeutic Effects of FXR Activation, sEH Inhibition, and Dual FXR/sEH Modulation in NASH in Diet-Induced Obese MiceHelmstädter, Moritz / Schmidt, Jurema / Kaiser, Astrid / Weizel, Lilia / Proschak, Ewgenij / Merk, Daniel et al. | 2021
- 980
-
N‑Adamantyl Phthalimidine: A New Thalidomide-like Drug That Lacks Cereblon Binding and Mitigates Neuronal and Synaptic Loss, Neuroinflammation, and Behavioral Deficits in Traumatic Brain Injury and LPS ChallengeHsueh, Shih Chang / Luo, Weiming / Tweedie, David / Kim, Dong Seok / Kim, Yu Kyung / Hwang, Inho / Gil, Jung-Eun / Han, Baek-Soo / Chiang, Yung-Hsiao / Selman, Warren et al. | 2021
- 1001
-
Compensatory Transition of Bile Acid Metabolism from Fecal Disposition of Secondary Bile Acids to Urinary Excretion of Primary Bile Acids Underlies Rifampicin-Induced Cholestasis in Beagle DogsGui, LanLan / Wu, QingLiang / Hu, YiTing / Zeng, WuShuang / Tan, XianWen / Zhu, PingPing / Li, XueJing / Yang, Lian / Jia, Wei / Liu, ChangXiao et al. | 2021
- 1014
-
Brain-Eating Amoebae in the United Arab Emirates?Siddiqui, Ruqaiyyah / Khamis, Mustafa / Ibrahim, Taleb / Khan, Naveed Ahmed et al. | 2021
- 1016
-
SARS-CoV‑2 Glycosylation Suggests That Vaccines Should Have Adopted the S1 Subunit as AntigenFernández, Ariel et al. | 2021
- 1018
-
Toward the Next-Generation COVID-19 Vaccines That Circumvent Antigenic Drift while Defusing Viral InfectionFernández, Ariel et al. | 2021
- 1021
-
COVID-19: Does SARS-CoV‑2 Modulate Acanthamoeba Epigenetics to Enhance Survival and Transmission in the Environment?Muhammad, Jibran Sualeh / Siddiqui, Ruqaiyyah / Khan, Naveed Ahmed et al. | 2021
- 1024
-
COVID-19: Is There a Link between Alcohol Abuse and SARS-CoV-2-Induced Severe Neurological Manifestations?Muhammad, Jibran Sualeh / Siddiqui, Ruqaiyyah / Khan, Naveed Ahmed et al. | 2021