X-ray Crystal Structure and Binding Mode Analysis of Human S-Adenosylhomocysteine Hydrolase Complexed with Novel Mechanism-Based Inhibitors, Haloneplanocin A Analogues (Unbekannt)
- Neue Suche nach: Lee, Kang Man
- Neue Suche nach: Choi, Won Jun
- Neue Suche nach: Lee, Yoonji
- Neue Suche nach: Lee, Hyun Joo
- Neue Suche nach: Zhao, Long Xuan
- Neue Suche nach: Lee, Hyuk Woo
- Neue Suche nach: Park, Jae Gyu
- Neue Suche nach: Kim, Hea Ok
- Neue Suche nach: Hwang, Kwang Yeon
- Neue Suche nach: Heo, Yong-Seok
- Neue Suche nach: Choi, Sun
- Neue Suche nach: Jeong, Lak Shin
- Neue Suche nach: Lee, Kang Man
- Neue Suche nach: Choi, Won Jun
- Neue Suche nach: Lee, Yoonji
- Neue Suche nach: Lee, Hyun Joo
- Neue Suche nach: Zhao, Long Xuan
- Neue Suche nach: Lee, Hyuk Woo
- Neue Suche nach: Park, Jae Gyu
- Neue Suche nach: Kim, Hea Ok
- Neue Suche nach: Hwang, Kwang Yeon
- Neue Suche nach: Heo, Yong-Seok
- Neue Suche nach: Choi, Sun
- Neue Suche nach: Jeong, Lak Shin
In:
Journal of Medicinal Chemistry
;
54
, 4
;
930-938
;
2011
- Aufsatz (Zeitschrift) / Elektronische Ressource
-
Titel:X-ray Crystal Structure and Binding Mode Analysis of Human S-Adenosylhomocysteine Hydrolase Complexed with Novel Mechanism-Based Inhibitors, Haloneplanocin A Analogues
-
Weitere Titelangaben:J. Med. Chem.
-
Beteiligte:Lee, Kang Man ( Autor:in ) / Choi, Won Jun ( Autor:in ) / Lee, Yoonji ( Autor:in ) / Lee, Hyun Joo ( Autor:in ) / Zhao, Long Xuan ( Autor:in ) / Lee, Hyuk Woo ( Autor:in ) / Park, Jae Gyu ( Autor:in ) / Kim, Hea Ok ( Autor:in ) / Hwang, Kwang Yeon ( Autor:in ) / Heo, Yong-Seok ( Autor:in )
-
Erschienen in:Journal of Medicinal Chemistry ; 54, 4 ; 930-938
-
Verlag:
- Neue Suche nach: American Chemical Society
-
Erscheinungsdatum:24.02.2011
-
ISSN:
-
Coden:
-
DOI:
-
Medientyp:Aufsatz (Zeitschrift)
-
Format:Elektronische Ressource
-
Sprache:Unbekannt
-
Datenquelle:
Inhaltsverzeichnis – Band 54, Ausgabe 4
Zeige alle Jahrgänge und Ausgaben
Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
- 915
-
ATP-Binding Site of Bacterial Enzymes as a Target for Antibacterial Drug DesignŠkedelj, Veronika / Tomašić, Tihomir / Mašič, Lucija Peterlin / Zega, Anamarija et al. | 2011
- 930
-
X-ray Crystal Structure and Binding Mode Analysis of Human S-Adenosylhomocysteine Hydrolase Complexed with Novel Mechanism-Based Inhibitors, Haloneplanocin A AnaloguesLee, Kang Man / Choi, Won Jun / Lee, Yoonji / Lee, Hyun Joo / Zhao, Long Xuan / Lee, Hyuk Woo / Park, Jae Gyu / Kim, Hea Ok / Hwang, Kwang Yeon / Heo, Yong-Seok et al. | 2011
- 939
-
Development and Evaluation of Endothelin-A Receptor (Radio)Ligands for Positron Emission TomographyMichel, Kristin / Büther, Katrin / Law, Marilyn P. / Wagner, Stefan / Schober, Otmar / Hermann, Sven / Schäfers, Michael / Riemann, Burkhard / Höltke, Carsten / Kopka, Klaus et al. | 2011
- 949
-
Synthesis and Evaluation of ^1^1C-Labeled Imidazo[2,1-b]benzothiazoles (IBTs) as PET Tracers for Imaging beta -Amyloid Plaques in Alzheimer's DiseaseYousefi, B.H. / Manook, A. / Drzezga, A. / Reutern, B.v. / Schwaiger, M. / Wester, H.-J. / Henriksen, G. et al. | 2011
- 949
-
Synthesis and Evaluation of 11C-Labeled Imidazo[2,1-b]benzothiazoles (IBTs) as PET Tracers for Imaging β-Amyloid Plaques in Alzheimer’s DiseaseYousefi, Behrooz H. / Manook, André / Drzezga, Alexander / v. Reutern, Boris / Schwaiger, Markus / Wester, Hans-Jürgen / Henriksen, Gjermund et al. | 2011
- 957
-
Probes for Narcotic Receptor Mediated Phenomena. 41. Unusual Inverse μ-Agonists and Potent μ-Opioid Antagonists by Modification of the N-Substituent in Enantiomeric 5-(3-Hydroxyphenyl)morphansCheng, Kejun / Lee, Yong Sok / Rothman, Richard B. / Dersch, Christina M. / Bittman, Ross W. / Jacobson, Arthur E. / Rice, Kenner C. et al. | 2011
- 970
-
In Vivo Trypanosomicidal Activity of Imidazole- or Pyrazole-Based Benzo[g]phthalazine Derivatives against Acute and Chronic Phases of Chagas DiseaseSánchez-Moreno, Manuel / Sanz, Ana M. / Gómez-Contreras, Fernando / Navarro, Pilar / Marín, Clotilde / Ramírez-Macias, Inmaculada / Rosales, María Jose / Olmo, Francisco / Garcia-Aranda, Isabel / Campayo, Lucrecia et al. | 2011
- 980
-
Synthesis and Pharmacological Activities of 6-Glycine Substituted 14-Phenylpropoxymorphinans, a Novel Class of Opioids with High Opioid Receptor Affinities and Antinociceptive PotenciesSpetea, Mariana / Windisch, Petra / Guo, Yan / Bileviciute-Ljungar, Indre / Schütz, Johannes / Asim, Muhammad Faheem / Berzetei-Gurske, Ilona P. / Riba, Pal / Kiraly, Kornel / Fürst, Susanna et al. | 2011
- 989
-
Cationic Surfactants Derived from Lysine: Effects of Their Structure and Charge Type on Antimicrobial and Hemolytic ActivitiesColomer, A. / Pinazo, A. / Manresa, M. A. / Vinardell, M. P. / Mitjans, M. / Infante, M. R. / Pérez, L. et al. | 2011
- 1003
-
Electron Paramagnetic Resonance (EPR) Study of Spin-Labeled Camptothecin Derivatives: A Different Look of the Ternary ComplexRicci, Antonio / Marinello, Jessica / Bortolus, Marco / Sánchez, Albert / Grandas, Anna / Pedroso, Enrique / Pommier, Yves / Capranico, Giovanni / Maniero, Anna Lisa / Zagotto, Giuseppe et al. | 2011
- 1010
-
2-Aminothiazoles as Therapeutic Leads for Prion DiseasesGallardo-Godoy, Alejandra / Gever, Joel / Fife, Kimberly L. / Silber, B. Michael / Prusiner, Stanley B. / Renslo, Adam R. et al. | 2011
- 1022
-
Analogues of sigma Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthaien-1-yl)propyl]-piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography RadiotracersAbate, C. / Niso, M. / Lacivita, E. / Mosier, P.D. / Toscano, A. / Perrone, R. et al. | 2011
- 1022
-
Analogues of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography RadiotracersAbate, Carmen / Niso, Mauro / Lacivita, Enza / Mosier, Philip D. / Toscano, Annamaria / Perrone, Roberto et al. | 2011
- 1033
-
Evaluation of Quinazoline Analogues as Glucocerebrosidase Inhibitors with Chaperone ActivityMarugan, Juan J. / Zheng, Wei / Motabar, Omid / Southall, Noel / Goldin, Ehud / Westbroek, Wendy / Stubblefield, Barbara K. / Sidransky, Ellen / Aungst, Ronald A. / Lea, Wendy A. et al. | 2011
- 1059
-
Acyloxy Nitroso Compounds as Nitroxyl (HNO) Donors: Kinetics, Reactions with Thiols, and Vasodilation PropertiesShoman, Mai E. / DuMond, Jenna F. / Isbell, T. S. / Crawford, J. H. / Brandon, Angela / Honovar, Jaideep / Vitturi, Dario A. / White, C. R. / Patel, R. P. / King, S. Bruce et al. | 2011
- 1071
-
Discovery and Biological Characterization of (2R,4S)-1′-Acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-N-methyl-4,4′-bipiperidine-1-carboxamide as a New Potent and Selective Neurokinin 1 (NK1) Receptor Antagonist Clinical CandidateDi Fabio, Romano / Alvaro, Giuseppe / Griffante, Cristiana / Pizzi, Domenica A. / Donati, Daniele / Mattioli, Mario / Cimarosti, Zadeo / Guercio, Giuseppe / Marchioro, Carla / Provera, Stefano et al. | 2011
- 1080
-
Biotin Ergopeptide Probes for Dopamine ReceptorsVendrell, Marc / Molero, Anabel / González, Sergio / Pérez-Capote, Kamil / Lluis, Carme / McCormick, Peter J. / Franco, Rafael / Cortés, Antoni / Casadó, Vicent / Albericio, Fernando et al. | 2011
- 1091
-
Convergent Evolution-Guided Design of Antimicrobial Peptides Derived from Influenza A Virus HemagglutininZhu, Shunyi / Aumelas, André / Gao, Bin et al. | 2011
- 1096
-
Development of Non-Peptide Ligands of Growth Factor Receptor-Bound Protein 2-Src Homology 2 Domain Using Molecular Modeling and NMR SpectroscopyOrcajo-Rincón, Ángel L. / Ortega-Gutiérrez, Silvia / Serrano, Pedro / Torrecillas, Ivan R. / Wüthrich, Kurt / Campillo, Mercedes / Pardo, Leonardo / Viso, Alma / Benhamú, Bellinda / López-Rodríguez, María L. et al. | 2011
- 1101
-
3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile (S1) Based Molecules as Potent, Dual Inhibitors of B-Cell Lymphoma 2 (Bcl-2) and Myeloid Cell Leukemia Sequence 1 (Mcl-1): Structure-Based Design and Structure−Activity Relationship StudiesZhang, Zhichao / Wu, Guiye / Xie, Feibo / Song, Ting / Chang, Xilong et al. | 2011
- 1106
-
Discovery, Synthesis, and Structure−Activity Relationship Development of a Series of N-(4-Acetamido)phenylpicolinamides as Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4) with CNS Exposure in RatsEngers, Darren W. / Field, Julie R. / Le, Uyen / Zhou, Ya / Bolinger, Julie D. / Zamorano, Rocio / Blobaum, Anna L. / Jones, Carrie K. / Jadhav, Satyawan / Weaver, C. David et al. | 2011