Cryptochinones from Cryptocarya chinensis act as farnesoid X receptor agonists (Englisch)
- Neue Suche nach: Lin, Hsiang-Ru
- Neue Suche nach: Chou, Tsung-Hsien
- Neue Suche nach: Huang, Din-Wen
- Neue Suche nach: Chen, Ih-Sheng
- Neue Suche nach: Lin, Hsiang-Ru
- Neue Suche nach: Chou, Tsung-Hsien
- Neue Suche nach: Huang, Din-Wen
- Neue Suche nach: Chen, Ih-Sheng
In:
Bioorganic and Medicinal Chemistry Letters
;
24
, 17
;
4181-4186
;
2014
-
ISSN:
- Aufsatz (Zeitschrift) / Elektronische Ressource
-
Titel:Cryptochinones from Cryptocarya chinensis act as farnesoid X receptor agonists
-
Beteiligte:Lin, Hsiang-Ru ( Autor:in ) / Chou, Tsung-Hsien ( Autor:in ) / Huang, Din-Wen ( Autor:in ) / Chen, Ih-Sheng ( Autor:in )
-
Erschienen in:Bioorganic and Medicinal Chemistry Letters ; 24, 17 ; 4181-4186
-
Verlag:
- Neue Suche nach: Elsevier Ltd
-
Erscheinungsdatum:16.07.2014
-
Format / Umfang:6 pages
-
ISSN:
-
DOI:
-
Medientyp:Aufsatz (Zeitschrift)
-
Format:Elektronische Ressource
-
Sprache:Englisch
-
Schlagwörter:
-
Datenquelle:
Inhaltsverzeichnis – Band 24, Ausgabe 17
Zeige alle Jahrgänge und Ausgaben
Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
- 4059
-
Graphical contents list| 2014
- 4073
-
GPCR structures in drug design, emerging opportunities with new structuresTautermann, Christofer S. et al. | 2014
- 4080
-
4-Substituted quinazoline derivatives as novel EphA2 receptor tyrosine kinase inhibitorsLim, Chae Jo / Oh, Kwang-Seok / Ha, Jae Du / Lee, Jeong Hyun / Seo, Ho Won / Chae, Chong Hack / Kim, Dae-Ghon / Lee, Mi-Jin / Lee, Byung Ho et al. | 2014
- 4084
-
Repurposing human PDE4 inhibitors for neglected tropical diseases: Design, synthesis and evaluation of cilomilast analogues as Trypanosoma brucei PDEB1 inhibitorsAmata, Emanuele / Bland, Nicholas D. / Hoyt, Charles T. / Settimo, Luca / Campbell, Robert K. / Pollastri, Michael P. et al. | 2014
- 4090
-
Scaffold hopping of sampangine: Discovery of potent antifungal lead compound against Aspergillus fumigatus and Cryptococcus neoformansJiang, Zhigan / Liu, Na / Dong, Guoqiang / Jiang, Yan / Liu, Yang / He, Xiaomeng / Huang, Yahui / He, Shipeng / Chen, Wei / Li, Zhengang et al. | 2014
- 4095
-
Phorbaketals L–N, cytotoxic sesterterpenoids isolated from the marine sponge of the genus PhorbasLee, Yehee / Wang, Weihong / Kim, Hiyoung / Giri, Awadut G. / Won, Dong Hwan / Hahn, Dongyup / Baek, Kyung Ryul / Lee, Jihye / Yang, Inho / Choi, Hyukjae et al. | 2014
- 4099
-
The binding mechanisms of plasma protein to active compounds in Alismaorientale rhizomes (Alismatis Rhizoma)Xu, Fei / Wu, Qi-nan / Chen, Jun / Gu, Wei / Fang, Fang / Zhang, Lin-qun / Zhao, Bo et al. | 2014
- 4106
-
In search of next generation antimalarialsChatterjee, Sankar / Tanabe, Keiichi / Nodiff, Edward A. et al. | 2014
- 4110
-
Discovery of pyrrolo-benzo-1,4-diazines as potent Nav1.7 sodium channel blockersHo, Ginny D. / Tulshian, Deen / Bercovici, Ana / Tan, Zheng / Hanisak, Jennifer / Brumfield, Stephanie / Matasi, Julius / Heap, Charles R. / Earley, William G. / Courneya, Brandy et al. | 2014
- 4114
-
Oleanolic acid analogs as NO, TNF-α and IL-1β inhibitors: Synthesis, biological evaluation and docking studiesBhandari, Pamita / Patel, Neeraj Kumar / Gangwal, Rahul P. / Sangamwar, Abhay T. / Bhutani, Kamlesh Kumar et al. | 2014
- 4114
-
Oleanolic acid analogs as NO, TNF- alpha and IL-1 beta inhibitors: Synthesis, biological evaluation and docking studiesBhandari, P. / Patel, N.K. / Gangwal, R.P. / Sangamwar, A.T. / Bhutani, K.K. et al. | 2014
- 4120
-
A new phenylpropanoid and an alkylglycoside from Piper retrofractum leaves with their antioxidant and α-glucosidase inhibitory activityLuyen, Bui Thi Thuy / Tai, Bui Huu / Thao, Nguyen Phuong / Yang, Seo Young / Cuong, Nguyen Manh / Kwon, Young In / Jang, Hae Dong / Kim, Young Ho et al. | 2014
- 4120
-
A new phenylpropanoid and an alkylglycoside from Piper retrofractum leaves with their antioxidant and alpha -glucosidase inhibitory activityLuyen, B.T.T. / Tai, B.H. / Thao, N.P. / Yang, S.Y. / Cuong, N.M. / Kwon, Y.I. / Jang, H.D. / Kim, Y.H. et al. | 2014
- 4125
-
Synthesis and biological evaluation of novel thiadiazole amides as potent Cdc25B and PTP1B inhibitorsLi, Yingjun / Yu, Yang / Jin, Kun / Gao, Lixin / Luo, Tongchuan / Sheng, Li / Shao, Xin / Li, Jia et al. | 2014
- 4129
-
Cellular differentiation assessments by measuring the degree of cellular internalization and membrane adsorption using designed peptidesUsui, Kenji / Kikuchi, Takuya / Kikuchi, Kunio / Mie, Masayasu / Kobatake, Eiry / Mihara, Hisakazu et al. | 2014
- 4132
-
Kinase domain inhibition of leucine rich repeat kinase 2 (LRRK2) using a [1,2,4]triazolo[4,3-b]pyridazine scaffoldGalatsis, Paul / Henderson, Jaclyn L. / Kormos, Bethany L. / Han, Seungil / Kurumbail, Ravi G. / Wager, Travis T. / Verhoest, Patrick R. / Noell, G. Stephen / Chen, Yi / Needle, Elie et al. | 2014
- 4141
-
Structure-based optimization of non-peptidic Cathepsin D inhibitorsGrädler, Ulrich / Czodrowski, Paul / Tsaklakidis, Christos / Klein, Markus / Werkmann, Daniela / Lindemann, Sven / Maskos, Klaus / Leuthner, Birgitta et al. | 2014
- 4151
-
2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymesCarballeira, Néstor M. / Bwalya, Angela Gono / Itoe, Maurice Ayamba / Andricopulo, Adriano D. / Cordero-Maldonado, María Lorena / Kaiser, Marcel / Mota, Maria M. / Crawford, Alexander D. / Guido, Rafael V.C. / Tasdemir, Deniz et al. | 2014
- 4158
-
Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase–dihydrofolate reductaseKumar, Vidya P. / Cisneros, Jose A. / Frey, Kathleen M. / Castellanos-Gonzalez, Alejandro / Wang, Yiqiang / Gangjee, Aleem / White, A. Clinton Jr. / Jorgensen, William L. / Anderson, Karen S. et al. | 2014
- 4162
-
Structure–activity studies of (−)-epigallocatechin gallate derivatives as HCV entry inhibitorsBhat, Rohit / Adam, Amna T. / Lee, Jungeun Jasmine / Deloison, Gaspard / Rouillé, Yves / Séron, Karin / Rotella, David P. et al. | 2014
- 4166
-
New class of methyl tetrazole based hybrid of (Z)-5-benzylidene-2-(piperazin-1-yl)thiazol-4(%H)-one as potent antitubercular agentsChauhan, Kuldeep / Sharma, Moni / Trivedi, Priyanka / Chaturvedi, Vinita / Chauhan, Prem M.S. et al. | 2014
- 4171
-
Evaluation of the cyclopentane-1,2-dione as a potential bio-isostere of the carboxylic acid functional groupBallatore, Carlo / Gay, Bryant / Huang, Longchuan / Robinson, Katie Herbst / James, Michael J. / Trojanowski, John Q. / Lee, Virginia M.-Y. / Brunden, Kurt R. / Smith, Amos B. III et al. | 2014
- 4176
-
Submonomer synthesis of azapeptide ligands of the Insulin Receptor Tyrosine Kinase domainKurian, Lathamol A. / Silva, Tammy A. / Sabatino, David et al. | 2014
- 4181
-
Cryptochinones from Cryptocarya chinensis act as farnesoid X receptor agonistsLin, Hsiang-Ru / Chou, Tsung-Hsien / Huang, Din-Wen / Chen, Ih-Sheng et al. | 2014
- 4187
-
Structure-based design of novel human Pin1 inhibitors (III): Optimizing affinity beyond the phosphate recognition pocketGuo, Chuangxing / Hou, Xinjun / Dong, Liming / Marakovits, Joseph / Greasley, Samantha / Dagostino, Eleanor / Ferre, RoseAnn / Catherine Johnson, M. / Humphries, Paul S. / Li, Haitao et al. | 2014
- 4192
-
Synthesis and evaluation of naphthoflavones as a new class of non purine xanthine oxidase inhibitorsSingh, Harbinder / Sharma, Sahil / Ojha, Ritu / Gupta, Manish K. / Nepali, Kunal / Bedi, P.M.S. et al. | 2014
- 4198
-
Second generation, arginine-rich (R–X′–R)4-type cell-penetrating α–ω–α-peptides with constrained, chiral ω-amino acids (X′) for enhanced cargo delivery into cellsPatil, Kiran M. / Naik, Rangeetha J. / Vij, Manika / Yadav, Amit K. / Kumar, Vaijayanti A. / Ganguli, Munia / Fernandes, Moneesha et al. | 2014
- 4198
-
Second generation, arginine-rich (R-X'-R)4-type cell-penetrating alpha - omega - alpha -peptides with constrained, chiral omega -amino acids (X') for enhanced cargo delivery into cellsPatil, K.M. / Naik, R.J. / Vij, M. / Yadav, A.K. / Kumar, V.A. / Ganguli, M. / Fernandes, M. et al. | 2014
- 4203
-
Triterpene glycosides from red ginseng marc and their anti-inflammatory activitiesChung, Ill-Min / Kim, Young-Ock / Ali, Mohammed / Kim, Seung-Hyun / Park, Inmyoung / Kim, Eun-Hye / Yang, Ye-Sul / Park, Hye-Ran / Son, Eun-Suk / Ahmad, Ateeque et al. | 2014
- 4209
-
Design, synthesis and in vitro evaluation of novel uni- and bivalent ligands for the cannabinoid receptor type 1 with variation of spacer length and structureHuang, Guozheng / Pemp, Daniela / Stadtmüller, Patricia / Nimczick, Martin / Heilmann, Jörg / Decker, Michael et al. | 2014
- 4215
-
Discovery and in vivo evaluation of alcohol-containing benzothiazoles as potent dual-targeting bacterial DNA supercoiling inhibitorsPalmer, James T. / Axford, Lorraine C. / Barker, Stephanie / Bennett, James M. / Blair, Michael / Collins, Ian / Davies, David T. / Ford, Leigh / Gannon, Carlie T. / Lancett, Paul et al. | 2014
- 4223
-
Development of chiral praziquantel analogues as potential drug candidates with activity to juvenile Schistosoma japonicumZheng, Yang / Dong, LanLan / Hu, Changyan / Zhao, Bo / Yang, Chunhua / Xia, Chaoming / Sun, Dequn et al. | 2014
- 4227
-
Synthesis of {[5-(adenin-9-yl)-2-furyl]methoxy}methyl phosphonic acid and evaluations against human adenylate kinasesKaci, Malika / Uttaro, Jean-Pierre / Lefort, Valérie / Mathé, Christophe / El Amri, Chahrazade / Périgaud, Christian et al. | 2014
- 4231
-
Cytotoxic activity of butane type of 1,7-seco-2,7′-cyclolignanes and apoptosis induction by Caspase 9 and 3Wukirsari, Tuti / Nishiwaki, Hisashi / Nishi, Kosuke / Sugahara, Takuya / Akiyama, Koichi / Kishida, Taro / Yamauchi, Satoshi et al. | 2014
- 4236
-
Synthesis and biological evaluation of unnatural derivatives of narciclasine: 7-aza-nornarciclasine and its N-oxideVshyvenko, Sergey / Reisenauer, Mary Rose / Rogelj, Snezna / Hudlicky, Tomas et al. | 2014
- 4239
-
Indolylmethylene benzo[h]thiazolo[2,3-b]quinazolinones: Synthesis, characterization and evaluation of anticancer and antimicrobial activitiesGali, Rajitha / Banothu, Janardhan / Porika, Mahendar / Velpula, Ravibabu / Hnamte, Sairengpuii / Bavantula, Rajitha / Abbagani, Sadanandam / Busi, Siddhardha et al. | 2014
- 4243
-
Synthesis and biological evaluation of novel isoxazoles and triazoles linked 6-hydroxycoumarin as potent cytotoxic agentsShakeel-u-Rehman / Masood-ur-Rahman / Tripathi, Vijay K. / Singh, Jasvinder / Ara, Tabassum / Koul, Surrinder / Farooq, Saleem / Kaul, Anupurna et al. | 2014
- 4247
-
A new series of HAPs as anti-HBV agents targeting at capsid assemblyYang, Xiu-yan / Xu, Xiao-qian / Guan, Hua / Wang, LI-li / Wu, Qin / Zhao, Guo-ming / Li, Song et al. | 2014
- 4250
-
New benzimidazole-2-urea derivates as tubulin inhibitorsWang, Wenna / Kong, Dexin / Cheng, Huimin / Tan, Li / Zhang, Zhang / Zhuang, Xiaoxi / Long, Huoyou / Zhou, Yang / Xu, Yong / Yang, Xiaohong et al. | 2014
- 4254
-
Synthesis and structure–activity relationship of non-peptidic antagonists of neuropilin-1 receptorLiu, Wang-Qing / Megale, Valentino / Borriello, Lucia / Leforban, Bertrand / Montès, Matthieu / Goldwaser, Elodie / Gresh, Nohad / Piquemal, Jean-Philip / Hadj-Slimane, Reda / Hermine, Olivier et al. | 2014
- 4260
-
Cytotoxic activity of substituted chalcones in terms of molecular electronic propertiesKupcewicz, Bogumiła / Jarzęcki, Andrzej A. / Małecka, Magdalena / Krajewska, Urszula / Rozalski, Marek et al. | 2014
- 4266
-
Discovery of furan-2-carbohydrazides as orally active glucagon receptor antagonistsHasegawa, Futoshi / Niidome, Kazumi / Migihashi, Chiaki / Murata, Makoto / Negoro, Toshiyuki / Matsumoto, Takafumi / Kato, Kaori / Fujii, Akihito et al. | 2014
- 4271
-
Discovery of novel pyrimidine and malonamide derivatives as TGR5 agonistsPark, Eun Ju / Ahn, Young Gil / Jung, Seung Hyun / Bang, Hyo Jeong / Kim, Mira / Hong, Dong Jin / Kim, Jisook / Suh, Kwee Hyun / Kim, Young Jin / Kim, Doran et al. | 2014
- 4276
-
Synthesis and inhibitory activity on hepatitis C virus RNA replication of 4-(1,1,1,3,3,3-hexafluoro-2-hydroxy-2-propyl)aniline analogsMatsuno, Kenji / Ueda, Youki / Fukuda, Miwa / Onoda, Kenji / Waki, Minoru / Ikeda, Masanori / Kato, Nobuyuki / Miyachi, Hiroyuki et al. | 2014
- 4281
-
Synthesis and biological evaluation of thienopyrimidine derivatives as GPR119 agonistsJeon, Moon-Kook / Lee, Kyu Myung / Kim, Il Hyang / Jang, Yoon Kyung / Kang, Seung Kyu / Lee, Jun Mi / Jung, Kwan-Young / Kumar, Jaladi Ashok / Rhee, Sang Dal / Jung, Won Hoon et al. | 2014
- 4286
-
Phytochemical analysis and antileukemic activity of polyphenolic constituents of Toona sinensisKakumu, Akinori / Ninomiya, Masayuki / Efdi, Mai / Adfa, Morina / Hayashi, Masahiro / Tanaka, Kaori / Koketsu, Mamoru et al. | 2014
- 4291
-
Bahamaolide A from the marine-derived Streptomyces sp. CNQ343 inhibits isocitrate lyase in Candida albicansLee, So-Hyoung / Moon, Kyuho / Kim, Heegyu / Shin, Jongheon / Oh, Dong-Chan / Oh, Ki-Bong et al. | 2014
- 4294
-
Further evaluation of the tropane analogs of haloperidolSampson, Dinithia / Bricker, Barbara / Zhu, Xue Y. / Peprah, Kwakye / Lamango, Nazarius S. / Setola, Vincent / Roth, Bryan L. / Ablordeppey, Seth Y. et al. | 2014
- 4298
-
Characterization, antibacterial, antioxidant, and cytotoxic activities of ZnO nanoparticles using Coptidis RhizomaNagajyothi, P.C. / Sreekanth, T.V.M. / Tettey, Clement O. / Jun, Yang In / Mook, Shin Heung et al. | 2014
- 4304
-
Synthesis and evaluation of novel alkannin and shikonin oxime derivatives as potent antitumor agentsWang, Rubing / Zhang, Xu / Song, Hualong / Zhou, Shanshan / Li, Shaoshun et al. | 2014
- 4308
-
Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1Bravo, Yalda / Teriete, Peter / Dhanya, Raveendra-Panickar / Dahl, Russell / Lee, Pooi San / Kiffer-Moreira, Tina / Ganji, Santhi Reddy / Sergienko, Eduard / Smith, Layton H. / Farquharson, Colin et al. | 2014
- 4312
-
Inhibitory potency of flavonoid derivatives on influenza virus neuraminidaseRakers, Christin / Schwerdtfeger, Sverre-Morten / Mortier, Jérémie / Duwe, Susanne / Wolff, Thorsten / Wolber, Gerhard / Melzig, Matthias F. et al. | 2014
- 4318
-
Rupestonic acids B–G, NO inhibitory sesquiterpenoids from Artemisia rupestrisChen, Zhang / Wang, Shu / Zeng, Ke-Wu / Cui, Feng-Xia / Jin, Hong-Wei / Guo, Xiao-Yu / Jiang, Yong / Tu, Peng-Fei et al. | 2014
- 4323
-
Optimization of 2-phenyl-pyrimidine-4-carboxamides towards potent, orally bioavailable and selective P2Y12 antagonists for inhibition of platelet aggregationCaroff, Eva / Meyer, Emmanuel / Treiber, Alexander / Hilpert, Kurt / Riederer, Markus A. et al. | 2014
- 4332
-
Discovery and optimization of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonistsBuzard, Daniel J. / Kim, Sun Hee / Lehmann, Juerg / Han, Sangdon / Calderon, Imelda / Wong, Amy / Kawasaki, Andrew / Narayanan, Sanju / Bhat, Rohit / Gharbaoui, Tawfik et al. | 2014
- 4336
-
Discovery of S-adenosyl-l-homocysteine hydrolase inhibitors based on non-adenosine analogsNakao, Akira / Suzuki, Hiroko / Ueno, Hiroaki / Iwasaki, Hiroshi / Setsuta, Tomofumi et al. | 2014
- 4341
-
The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting beta 2-adrenoceptor agonistArnold, N. / Beattie, D. / Bradley, M. / Brearley, A. / Brown, L. / Charlton, S.J. / Fairhurst, R.A. / Farr, D. / Fozard, J. / Fullerton, J. et al. | 2014
- 4341
-
The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonistArnold, Nicola / Beattie, David / Bradley, Michelle / Brearley, Andrew / Brown, Lyndon / Charlton, Steven J. / Fairhurst, Robin A. / Farr, David / Fozard, John / Fullerton, Joe et al. | 2014
- IFC
-
Editorial board| 2014