DMT1-mediated iron overload accelerates cartilage degeneration in Hemophilic Arthropathy through the mtDNA-cGAS-STING axis (Englisch)
- Neue Suche nach: Liu, Haigang
- Neue Suche nach: Chi, Ruimin
- Neue Suche nach: Xu, Jingting
- Neue Suche nach: Guo, Jiachao
- Neue Suche nach: Guo, Zhou
- Neue Suche nach: Zhang, Xiong
- Neue Suche nach: Hou, Liangcai
- Neue Suche nach: Zheng, Zehang
- Neue Suche nach: Lu, Fan
- Neue Suche nach: Xu, Tao
- Neue Suche nach: Sun, Kai
- Neue Suche nach: Guo, Fengjing
- Neue Suche nach: Liu, Haigang
- Neue Suche nach: Chi, Ruimin
- Neue Suche nach: Xu, Jingting
- Neue Suche nach: Guo, Jiachao
- Neue Suche nach: Guo, Zhou
- Neue Suche nach: Zhang, Xiong
- Neue Suche nach: Hou, Liangcai
- Neue Suche nach: Zheng, Zehang
- Neue Suche nach: Lu, Fan
- Neue Suche nach: Xu, Tao
- Neue Suche nach: Sun, Kai
- Neue Suche nach: Guo, Fengjing
In:
Biochimica et Biophysica Acta - Molecular Basis of Disease
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1870
, 4
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2024
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ISSN:
- Aufsatz (Zeitschrift) / Elektronische Ressource
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Titel:DMT1-mediated iron overload accelerates cartilage degeneration in Hemophilic Arthropathy through the mtDNA-cGAS-STING axis
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Beteiligte:Liu, Haigang ( Autor:in ) / Chi, Ruimin ( Autor:in ) / Xu, Jingting ( Autor:in ) / Guo, Jiachao ( Autor:in ) / Guo, Zhou ( Autor:in ) / Zhang, Xiong ( Autor:in ) / Hou, Liangcai ( Autor:in ) / Zheng, Zehang ( Autor:in ) / Lu, Fan ( Autor:in ) / Xu, Tao ( Autor:in )
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Erschienen in:
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Erscheinungsdatum:04.02.2024
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ISSN:
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DOI:
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Medientyp:Aufsatz (Zeitschrift)
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Format:Elektronische Ressource
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Sprache:Englisch
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Schlagwörter:HA , hemophilic Arthropathy , AAV9 , Adreno-Associated Virus 9 , cGAS , Cyclic GMP-AMP Synthase , DMT1 , Divalent metal transporter 1 , FVIII , coagulation factor VIII , H&E , hematoxylin-eosin , ECM , extracellular matrix , c-Myc , Cellular myelocytomatosis oncogene , LIP , labile iron pool , MDM2 , murine double minute 2 , IHC , immunohistochemistry , SAH , Subarachnoid hemorrhage , ROS , reactive oxygen species , MMP13 , matrix metallopeptidase 13 , NC , negative control , IL-6 , Interleukin 6 , DEGs , differential expressed genes , FPN1 , Ferroportin , NF-κB , Nuclear factor kappa B , IF , immunofluorescence , Tert , telomerase reverse transcriptase , FAC , Ferric ammonium citrate , siRNA , small interfering RNA , OARSI , Osteoarthritis Research Society International , KEGG , Kyoto Encyclopedia of Genes and Genomes , OA , osteoarthritis , STING , Stimulator of interferon genes , DCFH-DA , Dichloro-dihydro-fluorescein diacetate , CsA , Cyclosporin A , IL-1β , interleukin-1β , TEM , transmission electron microscopy , FTH1 , ferritin heavy chain 1 , RNA-seq , RNA sequencing , TFRC , transferrin receptor , IRF3 , Interferon regulatory factor 3 , Iron overload , Chondrocyte , Hemophilic arthropathy (HA) , Mitochondrial DNA , cGAS-STING
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Datenquelle:
Inhaltsverzeichnis – Band 1870, Ausgabe 4
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