Immunotherapy efficacy on mismatch repair-deficient colorectal cancer: From bench to bedside (Englisch)
- Neue Suche nach: Lizardo, Darleny Y.
- Neue Suche nach: Kuang, Chaoyuan
- Neue Suche nach: Hao, Suisui
- Neue Suche nach: Yu, Jian
- Neue Suche nach: Huang, Yi
- Neue Suche nach: Zhang, Lin
- Neue Suche nach: Lizardo, Darleny Y.
- Neue Suche nach: Kuang, Chaoyuan
- Neue Suche nach: Hao, Suisui
- Neue Suche nach: Yu, Jian
- Neue Suche nach: Huang, Yi
- Neue Suche nach: Zhang, Lin
In:
Biochimica et Biophysica Acta - Reviews on Cancer
;
1874
, 2
;
2020
-
ISSN:
- Aufsatz (Zeitschrift) / Elektronische Ressource
-
Titel:Immunotherapy efficacy on mismatch repair-deficient colorectal cancer: From bench to bedside
-
Beteiligte:Lizardo, Darleny Y. ( Autor:in ) / Kuang, Chaoyuan ( Autor:in ) / Hao, Suisui ( Autor:in ) / Yu, Jian ( Autor:in ) / Huang, Yi ( Autor:in ) / Zhang, Lin ( Autor:in )
-
Erschienen in:
-
Verlag:
- Neue Suche nach: Elsevier B.V.
-
Erscheinungsdatum:04.10.2020
-
ISSN:
-
DOI:
-
Medientyp:Aufsatz (Zeitschrift)
-
Format:Elektronische Ressource
-
Sprache:Englisch
-
Schlagwörter:Colorectal cancer , Mismatch repair deficiency , Microsatellite instability , Immunotherapy , Immune checkpoint inhibitors , Combination therapy , 5-FU , 5-fluorouracil , BAX , Bcl-2-associated X protein , B2M , beta-2-microglobulin , CAPEOX , capecitabine/oxaliplatin , CIN , chromosome instability , CMS , consensus molecular subtype , COX2 , cyclooxygenase 2 , CR , complete response , CRC , colorectal cancer , CTLA-4 , cytotoxic T-lymphocyte-associated antigen 4 , DCR , disease control rate , DFS , disease free survival , dMMR , mismatch repair deficient , DNMTi , DNA methyltransferase inhibitor , EGFR , epithelial growth factor receptor , FDA , Food and Drug Administration , FOLFIRI , 5-FU/leucovorin/irinotecan , FOLFOX , 5-FU/leucovorin/oxaliplatin , HDACi , histone deacetylase inhibitor , HLA , Human Leukocyte Antigen , ICD , immunogenic cell death , ICI , immune checkpoint inhibitor , IDO , indolamine-2,3-dioxygenase , indel , insertion-deletion , IFN-γ , interferon-γ , GI , gastrointestinal , LTB , low tumor burden , mCRC , metastatic colorectal cancer , MLH1 , mutL-homolog 1 , MMR , mismatch repair , MSH , MutS-Homologs , MSI , microsatellite instability , MSI-H , microsatellite instability-high , MSI-L , microsatellite instability-low , MSS , microsatellite stable , NK , natural killer , NKG2A , natural killer group 2A , ORR , objective response rate , OS , overall survival , PD-1 , Program Death 1 , PD-L1 , Programmed Death Ligand 1 , PFS , progression-free survival , pMMR , mismatch repair proficient , PMS2 , post-meiotic segregation 2 , PR , partial response , SBRT , stereotactic body radiation therapy , SOC , standard of care , TAA , tumor associated antigen , TGFBR2 , Transforming Growth Factor β Receptor II , TKI , tyrosine kinase inhibitor , TMB , tumor mutation burden , TILs , tumor infiltrating lymphocytes , TLR , Toll-like receptor , US , united states , VEGF , vascular endothelial growth factor
-
Datenquelle:
Inhaltsverzeichnis – Band 1874, Ausgabe 2
Zeige alle Jahrgänge und Ausgaben
Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
-
MYBL2 amplification in breast cancer: Molecular mechanisms and therapeutic potentialBayley, Rachel / Ward, Ciara / Garcia, Paloma et al. | 2020
-
Potential diagnostic and therapeutic roles of exosomes in pancreatic cancerZhao, Xiangxuan / Ren, Ying / Lu, Zaiming et al. | 2020
-
Mechanically stressed cancer microenvironment: Role in pancreatic cancer progressionHadden, Matthew / Mittal, Anubhav / Samra, Jaswinder / Zreiqat, Hala / Sahni, Sumit / Ramaswamy, Yogambha et al. | 2020
-
Cancer-associated fibroblasts in therapeutic resistance of pancreatic cancer: Present situation, predicaments, and perspectivesHan, Xuan / Zhang, Wu-Hu / Wang, Wen-Quan / Yu, Xian-Jun / Liu, Liang et al. | 2020
-
HOX genes and the NF-κB pathway: A convergence of developmental biology, inflammation and cancer biologyPai, Priya / Sukumar, Saraswati et al. | 2020
-
Cancer associated fibroblast mediated chemoresistance: A paradigm shift in understanding the mechanism of tumor progressionJena, Bikash Chandra / Das, Chandan Kanta / Bharadwaj, Deblina / Mandal, Mahitosh et al. | 2020
-
The ZAR1 protein in cancer; from epigenetic silencing to functional characterisation and epigenetic therapy of tumour suppressorsDeutschmeyer, Verena E. / Richter, Antje M. et al. | 2020
-
MCM family in gastrointestinal cancer and other malignancies: From functional characterization to clinical implicationWang, Yifei / Chen, Huarong / Zhang, Jinglin / Cheng, Alfred S.L. / Yu, Jun / To, Ka Fai / Kang, Wei et al. | 2020
-
Senescence and castration resistance in prostate cancer: A review of experimental evidence and clinical implicationsCarpenter, Valerie J. / Patel, Bhaumik B. / Autorino, Riccardo / Smith, Steven C. / Gewirtz, David A. / Saleh, Tareq et al. | 2020
-
Metabolic heterogeneity in cancer: An overview and therapeutic implicationsTong, Yu / Gao, Wei-Qiang / Liu, Yanfeng et al. | 2020
-
Immunotherapy efficacy on mismatch repair-deficient colorectal cancer: From bench to bedsideLizardo, Darleny Y. / Kuang, Chaoyuan / Hao, Suisui / Yu, Jian / Huang, Yi / Zhang, Lin et al. | 2020
-
The implication of long non-coding RNAs in the diagnosis, pathogenesis and drug resistance of pancreatic ductal adenocarcinoma and their possible therapeutic potentialPandya, Gouri / Kirtonia, Anuradha / Sethi, Gautam / Pandey, Amit Kumar / Garg, Manoj et al. | 2020
-
The PP2A subunit PR130 is a key regulator of cell development and oncogenic transformationDzulko, Melanie / Pons, Miriam / Henke, Andreas / Schneider, Günter / Krämer, Oliver H. et al. | 2020
-
LOXL2 in cancer: regulation, downstream effectors and novel rolesWen, Bing / Xu, Li-Yan / Li, En-Min et al. | 2020
-
Hepatocyte growth factor/MET and CD44 in colorectal cancer: partners in tumorigenesis and therapy resistanceJoosten, Sander P.J. / Spaargaren, Marcel / Clevers, Hans / Pals, Steven T. et al. | 2020
-
P53 in skin cancer: From a master player to a privileged target for prevention and therapyLoureiro, J.B. / Abrantes, M. / Oliveira, P.A. / Saraiva, L. et al. | 2020
-
The use of minimally invasive biomarkers for the diagnosis and prognosis of hepatocellular carcinomaTrevisan França de Lima, Lucas / Broszczak, Daniel / Zhang, Xi / Bridle, Kim / Crawford, Darrell / Punyadeera, Chamindie et al. | 2020
-
PTEN in osteosarcoma: Recent advances and the therapeutic potentialZheng, Chuanxi / Tang, Fan / Min, Li / Hornicek, Francis / Duan, Zhenfeng / Tu, Chongqi et al. | 2020
-
Extracellular proteolysis in glioblastoma progression and therapeuticsQuesnel, Agathe / Karagiannis, George S. / Filippou, Panagiota S. et al. | 2020
-
Protein phosphatase 1 in tumorigenesis: is it worth a closer look?Felgueiras, Juliana / Jerónimo, Carmen / Fardilha, Margarida et al. | 2020
-
The biology and engineered modeling strategies of cancer-nerve crosstalkGregory, Emory / Dugan, Reagan / David, Gabriel / Song, Young Hye et al. | 2020
-
Human MYC G-quadruplex: From discovery to a cancer therapeutic targetWang, Wenmeng / Hu, Shuangli / Gu, Yaru / Yan, Yunxiao / Stovall, Daniel B. / Li, Dangdang / Sui, Guangchao et al. | 2020
-
COVID-19 and cancer: A guide with suggested COVID-19 rule-out criteria to support clinical decision-makingLarson, Christopher / Oronsky, Bryan / Goyal, Sharad / Ray, Carolyn / Hedjran, Farah / Hammond, Terese C. / Kesari, Santosh / Caroen, Scott / Lybeck, Michelle / Dobalian, Vaughn E. et al. | 2020
-
Balancing neurotrophin pathway and sortilin function: Its role in human diseaseAl-Yozbaki, Minnatallah / Acha-Sagredo, Amelia / George, Alex / Liloglou, Triantafillos / Wilson, Cornelia M. et al. | 2020
-
Unmasking carcinoma-associated fibroblasts: Key transformation player within the tumor microenvironmentMeng, Qing / Luo, Xin / Chen, Jiaxin / Wang, Di / Chen, Engeng / Zhang, Wei / Zhang, Guolin / Zhou, Wei / Xu, Jianbin / Song, Zhangfa et al. | 2020
-
SOS GEFs in health and diseaseBaltanás, Fernando C. / Zarich, Natasha / Rojas-Cabañeros, Jose M. / Santos, Eugenio et al. | 2020
-
Protein glycosylation in head and neck cancers: From diagnosis to treatmentRasheduzzaman, Mohammad / Kulasinghe, Arutha / Dolcetti, Riccardo / Kenny, Liz / Johnson, Newell W. / Kolarich, Daniel / Punyadeera, Chamindie et al. | 2020
-
Oncometabolites lactate and succinate drive pro-angiogenic macrophage response in tumorsKes, Marjolein M.G. / Van den Bossche, Jan / Griffioen, Arjan W. / Huijbers, Elisabeth J.M. et al. | 2020
-
Latest perspectives on glucocorticoid-induced apoptosis and resistance in lymphoid malignanciesClarisse, Dorien / Offner, Fritz / De Bosscher, Karolien et al. | 2020
-
Targeting protein tyrosine kinase 6 in cancerGilic, Milica B. / Tyner, Angela L. et al. | 2020
-
EpCAM cellular functions in adhesion and migration, and potential impact on invasion: A critical reviewFagotto, François / Aslemarz, Azam et al. | 2020
-
Role of tyrosine phosphorylation in modulating cancer cell metabolismTaddei, Maria Letizia / Pardella, Elisa / Pranzini, Erica / Raugei, Giovanni / Paoli, Paolo et al. | 2020
-
Pharmacological significance of the non-canonical NF-κB pathway in tumorigenesisMorgan, Dhakshayini / Garg, Manoj / Tergaonkar, Vinay / Tan, Soo Yong / Sethi, Gautam et al. | 2020
-
Cancer regeneration: Polyploid cells are the key drivers of tumor progressionMoein, Shiva / Adibi, Rezvan / da Silva Meirelles, Lindolfo / Nardi, Nance Beyer / Gheisari, Yousof et al. | 2020
-
Biophysical signal transduction in cancer cells: Understanding its role in cancer pathogenesis and treatmentHuang, XiaoLei / Yang, XiaoXu / Sun, Chenchen / Huang, ShuXia / Cheng, Min / Han, Yangyang et al. | 2020
-
Power of two: combination of therapeutic approaches involving glucose transporter (GLUT) inhibitors to combat cancerTilekar, Kalpana / Upadhyay, Neha / Iancu, Cristina V. / Pokrovsky, Vadim / Choe, Jun-yong / Ramaa, C.S. et al. | 2020
-
Drug tolerance to target therapy in melanoma revealed at single cell level: What next?Liguoro, Domenico / Fattore, Luigi / Mancini, Rita / Ciliberto, Gennaro et al. | 2020
-
Nerve input to tumours: Pathophysiological consequences of a dynamic relationshipHutchings, Charlotte / Phillips, Jade A. / Djamgoz, Mustafa B.A. et al. | 2020
-
Choosing tumor mutational burden wisely for immunotherapy: A hard road to exploreLi, Rui / Han, Dongsheng / Shi, Jiping / Han, YanXi / Tan, Ping / Zhang, Rui / Li, Jinming et al. | 2020
-
Resistin: An inflammatory cytokine with multi-faceted roles in cancerSudan, Sarabjeet Kour / Deshmukh, Sachin Kumar / Poosarla, Teja / Holliday, Nicolette Paolaungthong / Dyess, Donna Lynn / Singh, Ajay Pratap / Singh, Seema et al. | 2020
-
Exosomes: The protagonists in the tale of colorectal cancer?Nabariya, Deepti Kailash / Pallu, Reddanna / Yenuganti, Vengala Rao et al. | 2020
-
Progress and challenge in development of biotherapeutics targeting MET receptor for treatment of advanced cancerYao, Hang-Ping / Hudson, Rachel / Wang, Ming-Hai et al. | 2020
-
Exosomes as Biomarkers of Human and Feline Mammary Tumours; A Comparative Medicine Approach to Unravelling the Aggressiveness of TNBCHoward, Jane / Wyse, Cathy / Argyle, David / Quinn, Cecily / Kelly, Pamela / McCann, Amanda et al. | 2020
-
Immunotherapy for advanced hepatocellular carcinoma, where are we?Zhang, Li / Ding, Jia / Li, Hui-Yan / Wang, Zhong-Hua / Wu, Jian et al. | 2020
-
Editorial Board| 2020
-
New insights into affinity proteins for HER2-targeted therapy: Beyond trastuzumabAkbari, Vajihe / Chou, C. Perry / Abedi, Daryoush et al. | 2020
-
The emerging role of miRNA clusters in breast cancer progressionKandettu, Amoolya / Radhakrishnan, Raghu / Chakrabarty, Sanjiban / Sriharikrishnaa, S. / Kabekkodu, Shama Prasada et al. | 2020
-
Targeting tumor-associated macrophages for cancer immunotherapyShu, Yongheng / Cheng, Ping et al. | 2020
-
The outstanding antitumor capacity of CD4+ T helper lymphocytesLi, Tong / Wu, Bowen / Yang, Tao / Zhang, Long / Jin, Ke et al. | 2020