PROTEIN STRUCTURE AND FOLDING - Mutational Analysis and Molecular Modeling of the Allosteric Binding Site of a Novel, Selective, Noncompetitive Antagonist of the Metabotropic Glutamate 1 Receptor. (Englisch)
- Neue Suche nach: Malherbe, Pari
- Neue Suche nach: Malherbe, Pari
- Neue Suche nach: Kratochwil, Nicole
- Neue Suche nach: Knoflach, Frédéric
- Neue Suche nach: Zenner, Marie-Thérèse
- Neue Suche nach: Kew, James N.C.
- Neue Suche nach: Kratzeisen, Claudia
- Neue Suche nach: Maerki, Hans P.
- Neue Suche nach: Adam, Geo
- Neue Suche nach: Mutel, Vincent
In:
The journal of biological chemistry
;
278
, 10
; 8340-8347
;
2003
-
ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:PROTEIN STRUCTURE AND FOLDING - Mutational Analysis and Molecular Modeling of the Allosteric Binding Site of a Novel, Selective, Noncompetitive Antagonist of the Metabotropic Glutamate 1 Receptor.
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Beteiligte:Malherbe, Pari ( Autor:in ) / Kratochwil, Nicole / Knoflach, Frédéric / Zenner, Marie-Thérèse / Kew, James N.C. / Kratzeisen, Claudia / Maerki, Hans P. / Adam, Geo / Mutel, Vincent
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Erschienen in:The journal of biological chemistry ; 278, 10 ; 8340-8347
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Verlag:
- Neue Suche nach: ASBMB
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Erscheinungsort:Bethesda, Md.
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Erscheinungsdatum:2003
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ISSN:
-
ZDBID:
-
Medientyp:Aufsatz (Zeitschrift)
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Format:Print
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Sprache:Englisch
- Neue Suche nach: 35.70 / 35.00
- Weitere Informationen zu Basisklassifikation
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Schlagwörter:
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Klassifikation:
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Datenquelle:
Inhaltsverzeichnis – Band 278, Ausgabe 10
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Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
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ACCELERATED PUBLICATIONS - Collagen Triple Helix Formation Can Be Nucleated at Either End.Frank, Sabine et al. | 2003
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PROTEIN STRUCTURE AND FOLDING - Two-dimensional NMR Study of the Heme Active Site Structure of Chloroperoxidase.Wang, Xiaotang et al. | 2003
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GLYCOBIOLOGY AND EXTRACELLULAR MATRICES - Fringe Modifies O-Fucose on Mouse Notch1 at Epidermal Growth Factor-like Repeats within the Ligand-binding Site and the Abruptex Region.Shao, Li et al. | 2003
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MECHANISMS OF SIGNAL TRANSDUCTION - Multiple Regions of Internalin B Contribute to Its Ability to Turn on the Ras-Mitogen-activated Protein Kinase Pathway.Copp, Jeremy et al. | 2003
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MECHANISMS OF SIGNAL TRANSDUCTION - A Kunitz-type Protease Inhibitor, Bikunin, Inhibits Ovarian Cancer Cell Invasion by Blocking the Calcium-dependent Transforming Growth Factor-b1 Signaling Cascade.Kobayashi, Hiroshi et al. | 2003
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ENZYME CATALYSIS AND REGULATION - Structural Determinants of the Calpain Inhibitory Activity of Calpastatin Peptide B27-WT.Betts, Russell et al. | 2003
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MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - Intravacuolar Membrane Lysis in Saccharomyces cerevisiae. DOES VACUOLAR TARGETING OF Cvt17-Aut5p AFFECT ITS FUNCTION?Epple, Ulrike D. et al. | 2003
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MECHANISMS OF SIGNAL TRANSDUCTION - GDP Affinity and Order State of the Catalytic Site Are Critical for Function of Xanthine Nucleotide-selective Ga Proteins.Gille, Andreas et al. | 2003
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ENZYME CATALYSIS AND REGULATION - Bacteriophage T4 Dam DNA-(N6-adenine)-methyltransferase. PROCESSIVITY AND ORIENTATION TO THE METHYLATION TARGET.Zinoviev, Victor V. et al. | 2003
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PROTEIN STRUCTURE AND FOLDING - Comparison of the Heme-free and -bound Crystal Structures of Human Heme Oxygenase-1.Lad, Latesh et al. | 2003
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LIPIDS AND LIPOPROTEINS - The mmaA2 Gene of Mycobacterium tuberculosis Encodes the Distal Cyclopropane Synthase of the a-Mycolic Acid.Glickman, Michael S. et al. | 2003
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MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - PEN-2 and APH-1 Coordinately Regulate Proteolytic Processing of Presenilin 1.Luo, Wen-jie et al. | 2003
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MECHANISMS OF SIGNAL TRANSDUCTION - H3 Relaxin Is a Specific Ligand for LGR7 and Activates the Receptor by Interacting with Both the Ectodomain and the Exoloop 2.Sudo, Satoko et al. | 2003
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GENOMICS, PROTEOMICS, AND BIOINFORMATICS - The Clf1p Splicing Factor Promotes Spliceosome Assembly through N-terminal Tetratricopeptide Repeat Contacts.Wang, Qiang et al. | 2003
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PROTEIN STRUCTURE AND FOLDING - Activity-Stability Relationships in Extremophilic Enzymes.D'Amico, Salvino et al. | 2003
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MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - PEX5 Binds the PTS1 Independently of Hsp70 and the Peroxin PEX12.Harper, Courtney C. et al. | 2003
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DNA: REPLICATION, REPAIR, AND RECOMBINATION - Incorporation of Uracil into Minus Strand DNA Affects the Specificity of Plus Strand Synthesis Initiation during Lentiviral Reverse Transcription.Klarmann, George J. et al. | 2003
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PROTEIN SYNTHESIS, POST-TRANSLATION MODIFICATION, AND DEGRADATION - Structural Determinants of Procryptdin Recognition and Cleavage by Matrix Metalloproteinase-7.Shirafuji, Yoshinori et al. | 2003
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MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - Co-translational Targeting and Translocation of the Amino Terminus of Opsin across the Endoplasmic Membrane Requires GTP but Not ATP.Kanner, Elliott M. et al. | 2003
- 7927
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METABOLISM AND BIOENERGETICS - Processing of an Antibacterial Peptide from Hemocyanin of the Freshwater Crayfish Pacifastacus leniusculus.Lee, So Young et al. | 2003
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MECHANISMS OF SIGNAL TRANSDUCTION - Inhibin Is an Antagonist of Bone Morphogenetic Protein Signaling.Wiater, Ezra et al. | 2003
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GLYCOBIOLOGY AND EXTRACELLULAR MATRICES - Genes Modulated by Expression of GD3 Synthase in Chinese Hamster Ovary Cells. EVIDENCE THAT THE Tis21 GENE IS INVOLVED IN THE INDUCTION OF GD3 9-O-ACETYLATION.Satake, Honoo et al. | 2003
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GLYCOBIOLOGY AND EXTRACELLULAR MATRICES - Delineation of the Hydroxyapatite-nucleating Domains of Bone Sialoprotein.Tye, Coralee E. et al. | 2003
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MECHANISMS OF SIGNAL TRANSDUCTION - R-Ras Glucosylation and Transient RhoA Activation Determine the Cytopathic Effect Produced by Toxin B Variants from Toxin A-negative Strains of Clostridium difficile.Chaves-Olarte, Esteban et al. | 2003
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GENES: STRUCTURE AND REGULATION - A Thyroid Hormone Response Unit Formed between the Promoter and First Intron of the Carnitine Palmitoyl-transferase-Ia Gene Mediates the Liver-specific Induction by Thyroid Hormone.Jackson-Hayes, Loretta et al. | 2003
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DNA: REPLICATION, REPAIR, AND RECOMBINATION - DNA-binding Mechanism of O6-Alkylguanine-DNA Alkyl-transferase. EFFECTS OF PROTEIN AND DNA ALKYLATION ON COMPLEX STABILITY.Rasimas, Joseph J. et al. | 2003
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PROTEIN STRUCTURE AND FOLDING - The Factor IX g-Carboxyglutamic Acid (Gla) Domain Is Involved in Interactions between Factor IX and Factor XIa.Aktimur, Aysar et al. | 2003
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MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - Rapid Flip-flop of Oleic Acid across the Plasma Membrane of Adipocytes.Kamp, Frits et al. | 2003
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PROTEIN STRUCTURE AND FOLDING - Molecular Basis of H2O2 Resistance Mediated by Streptococcal Dpr. DEMONSTRATION OF THE FUNCTIONAL INVOLVEMENT OF THE PUTATIVE FERROXIDASE CENTER BY SITE-DIRECTED MUTAGENESIS IN STREPTOCOCCUS SUIS.Pulliainen, Arta Tapio et al. | 2003
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DNA: REPLICATION, REPAIR, AND RECOMBINATION - Mechanism of Minus Strand Strong Stop Transfer in HIV-1 Reverse Transcription.Chen, Yan et al. | 2003
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MECHANISMS OF SIGNAL TRANSDUCTION - Nuclear Factor-kB and Mitogen-activated Protein Kinases Mediate Nitric Oxide-enhanced Transcriptional Expression of Interferon-b.Jacobs, Aaron T. et al. | 2003
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METABOLISM AND BIOENERGETICS - The Catabolism of Amino Acids to Long Chain and Complex Alcohols in Saccharomyces cerevisiae.Dickinson, J.Richard et al. | 2003
- 8035
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GLYCOBIOLOGY AND EXTRACELLULAR MATRICES - GlcNAc 2-Epimerase Can Serve a Catabolic Role in Sialic Acid Metabolism.Luchansky, Sarah J. et al. | 2003
- 8043
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LIPIDS AND LIPOPROTEINS - Novel Role for Apolipoprotein E in the Central Nervous System. MODULATION OF SULFATIDE CONTENT.Han, Xianlin et al. | 2003
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MECHANISMS OF SIGNAL TRANSDUCTION - The Amino-terminal Domain of G-protein-coupled Receptor Kinase 2 Is a Regulatory Gbg Binding Site.Eichmann, Tanja et al. | 2003
- 8058
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MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - Role of Reduced Glutathione Efflux in Apoptosis of Immortalized Human Keratinocytes Induced by UVA.He, Yu-Ying et al. | 2003
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PROTEIN STRUCTURE AND FOLDING - The FAR Protein Family of the Nematode Caenorhabditis elegans. DIFFERENTIAL LIPID BINDING PROPERTIES, STRUCTURAL CHARACTERISTICS, AND DEVELOPMENTAL REGULATION.Garofalo, Antonio et al. | 2003
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ENZYME CATALYSIS AND REGULATION - A Novel Bifunctional Wax Ester Synthase-Acyl-CoA.Diacylglycerol Acyltransferase Mediates Wax Ester and Triacylglycerol Biosynthesis in Acinetobacter calcoaceticus ADP1Kaischeuer, Rainer et al. | 2003
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MECHANISMS OF SIGNAL TRANSDUCTION - The Role of Focal Adhesion Kinase-Phosphatidylinositol 3-Kinase-Akt Signaling in Hepatic Stellate Cell Proliferation and Type I Collagen Expression.Reif, Shimon et al. | 2003
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ENZYME CATALYSIS AND REGULATION - Regulation of the Apaf-1-Caspase-9 Apoptosome by Caspase-3 and XIAP.Zou, Hua et al. | 2003
- 8099
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MECHANISMS OF SIGNAL TRANSDUCTION - Endothelial Nitric-oxide Synthase Enhances Lipopolysaccharide-stimulated Tumor Necrosis Factor-a Expression via cAMP-mediated p38 MARK Pathway in Cardiomyocytes.Peng, Tianqing et al. | 2003
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MECHANISMS OF SIGNAL TRANSDUCTION - cAMP-dependent Protein Kinase Enhances CYP17 Transcription via MKP-1 Activation in H295R Human Adrenocortical Cells.Sewer, Marion B. et al. | 2003
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DNA: REPLICATION, REPAIR, AND RECOMBINATION - High-affinity, Non-sequence-specific RNA Binding by the Open Reading Frame 1 (ORF1) Protein from Long Interspersed Nuclear Element 1 (LINE-1).Kolosha, Vladimir O. et al. | 2003
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MECHANISMS OF SIGNAL TRANSDUCTION - Negative Regulation of MAPKK by Phosphorylation of a Conserved Serine Residue Equivalent to Ser212 of MEK1.Gopalbhai, Kailesh et al. | 2003
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MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - Protein kinase C Mediates Translocation of Type II Phosphatidylinositol 5-Phosphate 4-Kinase Required for Platelet a-Granule Secretion.Rozenuayn, Nataliya et al. | 2003
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GENES: STRUCTURE AND REGULATION - Modulation of Gene Expression by Cancer Chemopreventive Dithiolethiones through the Keap1-Nrf2 Pathway. IDENTIFICATION OF NOVEL GENE CLUSTERS FOR CELL SURVIVAL.Kwak, Mi-Kyoung et al. | 2003
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MECHANISMS OF SIGNAL TRANSDUCTION - Insight into the Mechanism of Dopamine D1-like Receptor Activation. EVIDENCE FOR A MOLECULAR INTERPLAY BETWEEN THE THIRD EXTRACELLULAR LOOP AND THE CYTOPLASMIC TAILTumova, Katerina et al. | 2003
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ENZYME CATALYSIS AND REGULATION - Analysis of Heme Structural Heterogeneity in Mycobacterium tuberculosis Catalase-Peroxidase (KatG).Chouchane, Salem et al. | 2003
- 8163
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GENES: STRUCTURE AND REGULATION - Interaction of NF-E2 in the Human b-Globin Locus Control Region before Chromatin Remodeling.Onishi, Yoshiaki et al. | 2003
- 8172
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MECHANISMS OF SIGNAL TRANSDUCTION - Mutational Analysis of the Interaction between 14-3-3 Proteins and Plant Plasma Membrane H+-ATPase.Visconti, Sabina et al. | 2003
- 8179
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METABOLISM AND BIOENERGETICS - Mutagenesis of Prochlorothrix Plastocyanin Reveals Additional Features in Photosystem I Interactions.Hervás, Manuel et al. | 2003
- 8184
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MECHANISMS OF SIGNAL TRANSDUCTION - Nitric Oxide, NOC-12, and S-Nitrosoglutathione Modulate the Skeletal Muscle Calcium Release Channel-Ryanodine Receptor by Different Mechanisms. AN ALLOSTERIC FUNCTION FOR O2 IN S-NITROSYLATION OF THE CHANNEL.Sun, Junhui et al. | 2003
- 8190
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GENES: STRUCTURE AND REGULATION - Oxidative Stress Regulates Vascular Endothelial Growth Factor-A Gene Transcription through Sp1- and Sp3-dependent Activation of Two Proximal GC-rich Promoter Elements.Schäfer, Georgia et al. | 2003
- 8199
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MECHANISMS OF SIGNAL TRANSDUCTION - Modulation of Insulin-stimulated Degradation of Human Insulin Receptor Substrate-1 by Serine 312 Phosphorylation.Greene, Michael W. et al. | 2003
- 8212
-
GENES: STRUCTURE AND REGULATION - Dual Function of an Amino-terminal Amphipatic Helix in Androgen Receptor-mediated Transactivation through Specific and Nonspecific Response Elements.Callewaert, Leen et al. | 2003
- 8219
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MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - Bipartite Signals Mediate Subcellular Targeting of Tail-anchored Membrane Proteins in Saccharomyces cerevisiae.Beilharz, Traude et al. | 2003
- 8224
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GENES: STRUCTURE AND REGULATION - Interactions of SKIP-NCoA-62, TFIIB, and Retinoid X Receptor with Vitamin D Receptor Helix H10 Residues.Barry, Janelle B. et al. | 2003
- 8229
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MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - Nucleotide Interactions with Membrane-bound Transporter Associated with Antigen Processing Proteins.Lapinski, Philip Edward et al. | 2003
- 8238
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ENZYME CATALYSIS AND REGULATION - A Potent Cell-active Allosteric Inhibitor of Murine DNA Cytosine C5 Methyltransferase.Flynn, James et al. | 2003
- 8244
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MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - Sonic Hedgehog Induces Capillary Morphogenesis by Endothelial Cells through Phosphoinositide 3-Kinage.Kanda, Shigeru et al. | 2003
- 8250
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PROTEIN STRUCTURE AND FOLDING - Domain Structure Characterization of the Multifunctional a-Aminoadipate Reductase from Penicillium chrysogenum by Limited Proteolysis. ACTIVATION OF a-AMINOADIPATE DOES NOT REQUIRE THE PEPTIDYL CARRIER PROTEIN BOX OR THE REDUCTION DOMAIN.Hijarrubia, Maria José et al. | 2003
- 8257
-
PROTEIN SYNTHESIS, POST-TRANSLATION MODIFICATION, AND DEGRADATION - Membrane Type-1 Matrix Metalloproteinase Functions as a Proprotein Self-convertase. EXPRESSION OF THE LATENT ZYMOGEN IN PICHLA PASTORIS, AUTOLYTIC ACTIVATION, AND THE PEPTIDE SEQUENCE OF THE CLEAVAGE FORMS.Rozanov, Dmitri V. et al. | 2003
- 8261
-
DNA: REPLICATION, REPAIR, AND RECOMBINATION - Constitutive DNase 1 Hypersensitivity of p53-Regulated Promoters.Braastad, Corey D. et al. | 2003
- 8269
-
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - The Homeodomain Protein Barx2 Promotes Myogenic Differentiation and Is Regulated by Myogenic Regulatory Factors.Meech, Robyn et al. | 2003
- 8279
-
MECHANISMS OF SIGNAL TRANSDUCTION - Epac-selective cAMP Analog 8-pCPT-2'-O-Me-cAMP as a Stimulus for Ca2+-induced Ca2+ Release and Exocytosis in Pancreatic b-Cells.Kang, Guoxin et al. | 2003
- 8286
-
MECHANISMS OF SIGNAL TRANSDUCTION - RANK Ligand-induced Elevation of Cytosolic Ca2+ Accelerates Nuclear Translocation of Nuclear Factor kB in Osteoclasts.Komarova, Svetlana V. et al. | 2003
- 8294
-
MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - Three-dimensional Structures of the Mammalian Multi-drug Resistance P-glycoprotein Demonstrate Major Conformational Changes in the Transmembrane Domains upon Nucleotide Binding.Rosenberg, Mark F. et al. | 2003
- 8300
-
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - Astroglial c-Myc Overexpression Predisposes Mice to Primary Malignant Gliomas.Jensen, Niels A. et al. | 2003
- 8309
-
LIPIDS AND LIPOPROTEINS - Association of the Death-inducing Signaling Complex with Microdomains after Triggering through CD95-Fas. EVIDENCE FOR CASPASE-8-GANGLIOSIDE INTERACTION IN T CELLS.Garofalo, Tina et al. | 2003
- 8316
-
MECHANISMS OF SIGNAL TRANSDUCTION - Identification of Protein Kinase C Isozymes Responsible for the Phosphorylation of Photoreceptor-specific RGS9-1 at Ser475.Sokal, Izabela et al. | 2003
- 8326
-
MECHANISMS OF SIGNAL TRANSDUCTION - Defective Activation of c-Src in Cystic Fibrosis Airway Epithelial Cells Results in Loss of Tumor Necrosis Factor-a-induced Gap Junction Regulation.Huang, Song et al. | 2003
- 8333
-
PROTEIN STRUCTURE AND FOLDING - Crystal Structure of ATP Phosphoribosyltransferase from Mycobacterium tuberculosis.Cho, Yoonsang et al. | 2003
- 8340
-
PROTEIN STRUCTURE AND FOLDING - Mutational Analysis and Molecular Modeling of the Allosteric Binding Site of a Novel, Selective, Noncompetitive Antagonist of the Metabotropic Glutamate 1 Receptor.Malherbe, Pari et al. | 2003
- 8348
-
MECHANISMS OF SIGNAL TRANSDUCTION - A Noncontiguous, Intersubunit Binding Site for Calmodulin on the Skeletal Muscle Ca2+ Release Channel.Zhang, Hongwei et al. | 2003
- 8356
-
MECHANISMS OF SIGNAL TRANSDUCTION - Mammalian Ric-8A (Synembryn) Is a Heterotrimeric Ga Protein Guanine Nucleotide Exchange Factor.Tall, Gregory G. et al. | 2003
- 8363
-
PROTEIN STRUCTURE AND FOLDING - Mutagenesis of the g-Carboxyglutamic Acid Domain of Human Factor VII to Generate Maximum Enhancement of the Membrane Contact Site.Harvey, Stephen B. et al. | 2003
- 8370
-
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - Characterization of General Transcription Factor 3, a Transcription Factor Involved in Slow Muscle-specific Gene Expression.Vullhorst, Detlef et al. | 2003
- 8380
-
METABOLISM AND BIOENERGETICS - Lack of Tyrosine Nitration by Hypochlorous Acid in the Presence of Physiological Concentrations of Nitrite. IMPLICATIONS FOR THE ROLE OF NITRYL CHLORIDE IN TYROSINE NITRATION IN VIVO.Whiteman, Matthew et al. | 2003
- 8385
-
GENES: STRUCTURE AND REGULATION - The NFY Transcription Factor Inhibits von Willebrand Factor Promoter Activation in Non-endothelial Cells through Recruitment of Historic Deacetylases.Peng, Yiwen et al. | 2003
- 8395
-
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - Direct Interaction with a Kinesin-related Motor Mediates Transport of Mammalian Discs Large Tumor Suppressor Homologue in Epithelial Cells.Asaba, Noriyuki et al. | 2003
- 8401
-
LIPIDS AND LIPOPROTEINS - Functional Studies on Native and Mutated Forms of Perilipins. A ROLE IN PROTEIN KINASE A-MEDIATED LIPOLYSIS OF TRIACYLGLYCEROLS IN CHINESE HAMSTER OVARY CELLS.Tansey, John T. et al. | 2003
- 8407
-
PROTEIN STRUCTURE AND FOLDING - Fast Kinetics of Taxol Binding to Microtubules. EFFECTS OF SOLUTION VARIABLES AND MICROTLTBULE-ASSOCIATED PROTEINS.Diaz, José Fernando et al. | 2003
- 8420
-
LIPIDS AND LIPOPROTEINS - Structural Features of Glycosyltransferases Synthesizing Major Bilayer and Nonbilayer-prone Membrane Lipids in Acholeplasma laidlawii and Streptococcus pneumoniae.Edman, Maria et al. | 2003
- 8429
-
GENES: STRUCTURE AND REGULATION - Crystal Structures of the BtuF Periplasmic-binding Protein for Vitamin B12 Suggest a Functionally Important Reduction in Protein Mobility upon Ligand Binding.Karpowich, Nathan K. et al. | 2003
- 8435
-
GENES: STRUCTURE AND REGULATION - Up-regulation of CD14 in Liver Caused by Acute Ethanol Involves Oxidant-dependent AP-1 Pathway.Wheeler, Michael D. et al. | 2003
- 8442
-
PROTEIN STRUCTURE AND FOLDING - The Two Photocycles of Photoactive Yellow Protein from Rhodobacter sphaeroides.Haker, Andrea et al. | 2003
- 8452
-
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - Mouse MIM, a Tissue-specific Regulator of Cytoskeletal Dynamices, Interacts with ATP-Actin Monomers through Its C-terminal WH2 Domain.Mattila, Pieta K. et al. | 2003
- 8460
-
MECHANISMS OF SIGNAL TRANSDUCTION - Grb10 Inhibits Insulin-stimulated Insulin Receptor Substrate (IRS)-Phosphatidylinositol 3-Kinase-Akt Signaling Pathway by Disrupting the Association of IRS-1-IRS-2 with the Insulin Receptor.Wick, KeriLyn R. et al. | 2003
- 8468
-
DNA: REPLICATION, REPAIR, AND RECOMBINATION - Polo-like Kinase 1 and Chk2 Interact and Co-localize to Centrosomes and the Midbody.Tsvetkov, Lyuben et al. | 2003
- 8476
-
MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - Trafficking of the Ca2+-activated K+ Channel, hIK1, Is Dependent upon a C-terminal Leucine Zipper.Syme, Colin A. et al. | 2003
- 8487
-
GENOMICS, PROTEOMICS, AND BIOINFORMATICS - High Conservation of the Set1-Rad6 Axis of Histone 3 Lysine 4 Methylation in Budding and Fission Yeasts.Roguev, Assen et al. | 2003
- 8494
-
PROTEIN STRUCTURE AND FOLDING - Determinants of Rab5 Interaction with the N Terminus of Early Endosome Antigen 1.Merithew, Eric et al. | 2003
- 8501
-
PROTEIN STRUCTURE AND FOLDING - Crystal Structure of GRIP1 PDZ6-Peptide Complex Reveals the Structural Basis for Class Il PDZ Target Recognition and PDZ Domain-mediated Multimeirization.Im, Young Jun et al. | 2003
- 8508
-
MECHANISMS OF SIGNAL TRANSDUCTION - Angiogenic Effects of Interleukin 8 (CXCL8) in Human Intestinal Microvascular Endothelial Cells Are Mediated by CXCR2.Heidemann, Jan et al. | 2003
- 8516
-
MECHANISMS OF SIGNAL TRANSDUCTION - Mitochondrial Complex I Inhibitor Rotenone Induces Apoptosis through Enhancing Miochondrial Reactive Oxygen Species Production.Li, Nianyu et al. | 2003
- 8526
-
MECHANISMS OF SIGNAL TRANSDUCTION - Aurora-B Regulates the Cleavage Furrow-specific Vimentin Phosphorylation in the Cytokinetic Process.Goto, Hidemasa et al. | 2003
- 8531
-
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - Expression of Dominant-negative Fas-associated Death Domain Blocks Human Keratinocyte Apoptosis and Vesication Induced by Sulfur Mustard.Rosenthal, Dean S. et al. | 2003
- 8541
-
GLYCOBIOLOGY AND EXTRACELLULAR MATRICES - Discovery of an a2,9-PolyNeu5Ac Glycoprotein in C-1300 Murine Neuroblastoma (Clone NB41A3).Inoue, Sadako et al. | 2003
- 8547
-
ENZYME CATALYSIS AND REGULATION - Novel Natural Peptide Substrates for Endopeptidase 24.15, Neurolysin, and Angiotensin-converting Enzyme.Rioli, Vanessa et al. | 2003
- 8556
-
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - Identification and Molecular Characterization of a Chitinase from the Hard Tick Haemaphysalis longicornis.You, Myungio et al. | 2003
- 8564
-
MECHANISMS OF SIGNAL TRANSDUCTION - The Accessory Molecules CD5 and CD6 Associate on the Membrane of Lymphoid T Cells.Gimferrer, Idoia et al. | 2003
- 8572
-
MECHANISMS OF SIGNAL TRANSDUCTION - Apoptosis in leukemia Cells Is Accompanied by Alterations in the Levels and Localization of Nucleolin.Mi, Yingchang et al. | 2003
- 8580
-
GENES: STRUCTURE AND REGULATION - Cleavage, but Not Read-through, Stimulation Activity Is Responsible for Three Biologic Functions of Transcription Elongation Factor S-II.Ubukata, Toshiharu et al. | 2003
- 8586
-
MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - Characterization of Prominin-2, a New Member of the Prominin Family of Pentaspan Membrane Glycoproteins.Fargeas, Christine A. et al. | 2003
- 8597
-
MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - Dynamin-like Protein 1 Is Involved in Peroxisomal Fission.Koch, Annett et al. | 2003
- 8606
-
PROTEIN STRUCTURE AND FOLDING - Twists, Knots, and Rings in Proteins. STRUCTURAL DEFINITION OF THE CYCLOTIDE FRAMEWORK.Rosengren, K.Johan et al. | 2003
- 8617
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ENZYME CATALYSIS AND REGULATION - The Formation and Activity of PP2A Holoenzymes Do Not Depend on the Isoform of the Catalytic Subunit.Zhou, Jin et al. | 2003
- 8623
-
MECHANISMS OF SIGNAL TRANSDUCTION - CDK11 Complexes Promote Pre-mRNA Splicing.Hu, Dongli et al. | 2003
- 8630
-
PROTEIN STRUCTURE AND FOLDING - High Resolution Structure, Stability, and Synaptotagmin Binding of a Truncated Neuronal SNARE Complex.Ernst, James A. et al. | 2003
- 8637
-
GENES: STRUCTURE AND REGULATION - Ligand and Coactivator Identity Determines the Requirement of the Charge Clamp for Coactivation of the Peroxisome Proliferator-activated Receptor g.Wu, Yifei et al. | 2003
- 8645
-
MECHANISMS OF SIGNAL TRANSDUCTION - Rac2 Regulation of Phospholipase C-b2 Activity and Mode of Membrane Interactions in Intact Cells.Illenberger, Daria et al. | 2003
- 8653
-
DNA: REPLICATION, REPAIR, AND RECOMBINATION - Topoisomerase III Can Serve as the Cellular Decatenase in Escherichia coli.Nurse, Pearl et al. | 2003
- 8661
-
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - E-cadherin Negatively Regulates CD44-Hyaluronan Interaction and CD44-mediated Tumor Invasion and Branching Morphogenesis.Xu, Yin et al. | 2003
- 8669
-
MECHANISMS OF SIGNAL TRANSDUCTION - Leucine Zipper Domain Targets cAMP-dependent Protein Kinase to Mammalian BK Channels.Tian, Lijun et al. | 2003
- 8678
-
PROTEIN STRUCTURE AND FOLDING - The Core of the Tetrameric Mycobacterial Porin MspA Is an Extremely Stable b-Sheet Domain.Heinz, Christian et al. | 2003
- 8686
-
PROTEIN STRUCTURE AND FOLDING - Ca2+-induced Conformational Transition in the Inhibitory and Regulatory Regions of Cardiac Troponin I.Dong, Wen-Ji et al. | 2003
- 8693
-
GENES: STRUCTURE AND REGULATION - Cloning and Characterization of the Rat a1a-Adrenergic Receptor Gene Promoter. DEMONSTRATION OF CELL SPECIFICITY AND REGULATION BY HYPOXIA.Michelotti, Gregory A. et al. | 2003
- 8706
-
MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - Trafficking of TrkA-Green Fluorescent Protein Chimerae during Nerve Growth Factor-induced Differentiation.Jullien, Jérôme et al. | 2003
- 8717
-
PROTEIN STRUCTURE AND FOLDING - Molecular Basis of Isoform-specific m-Conotoxin Block of Cardiac, Skeletal Muscle, and Brain Na+ Channels.Li, Ronald A. et al. | 2003
- 8725
-
MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - HIV-1 Nef Stabilizes the Association of Adaptor Protein Complexes with Membranes.Janvier, Katy et al. | 2003
- 8733
-
ENZYME CATALYSIS AND REGULATION - Identification of Residues in Glutathione Transferase Capable of Driving Functional Diversification in Evolution. A NOVEL APPROACH TO PROTEIN REDESIGN.Ivarsson, Ylva et al. | 2003
- 8739
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DNA: REPLICATION, REPAIR, AND RECOMBINATION - The Main Role of Human Thymine-DNA Glycosylase Is Removal of Thymine Produced by Deamination of 5-Methylcytosine and Not Removal of Ethenocytosine.Abu, Mika et al. | 2003
- 8745
-
PROTEIN STRUCTURE AND FOLDING - A Novel Protein Tightly Bound to Bacterial Magnetic Particles in Magnetospirillum magneticum Strain AMIB-1.Arakaki, Atsushi et al. | 2003
- 8751
-
MECHANISMS OF SIGNAL TRANSDUCTION - Identification of a Novel Domain of Fibroblast Growth Factor 2 Controlling Its Angiogenic Properties.Facchiano, Antonio et al. | 2003
- 8761
-
PROTEIN STRUCTURE AND FOLDING - Structure of Escherichia coli 5'-Methylihioadenosine-S-Adenosylhomocysteine Nucleosidase Inhibitor Complexes Provide Insight into the Conformational Changes Required for Substrate Binding and Catalysis.Lee, Jeffrey E. et al. | 2003
- 8771
-
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - The C-terminal PDZ-Ligand of JAGGED1 Is Essential for Cellular Transformation.Ascano, Janice M. et al. | 2003
- 8780
-
GENES: STRUCTURE AND REGULATION - Functional Analysis of TBX5 Missense Mutations Associated with Holt-Oram Syndrome.Fan, Chun et al. | 2003
- 8786
-
MECHANISMS OF SIGNAL TRANSDUCTION - The a-Helical D1 Domain of the Tobacco bZIP Transcription Factor BZI-1 Interacts with the Ankyrin-repeat Protein ANK1 and Is Important for BZI-1 Function, Both in Auxin Signaling and Pathogen Response.Kuhlmann, Markus et al. | 2003
- 8795
-
DNA: REPLICATION, REPAIR, AND RECOMBINATION - NFBD1-KIAA0170 Is a Chromatin-associated Protein Involved in DNA Damage Signaling Pathways.Xu, Xingzhi et al. | 2003
- 8804
-
GENOMICS, PROTEOMICS, AND BIOINFORMATICS - Aspartate Dehydrogenase, a Novel Enzyme Identified from Structural and Functional Studies of TM1643.Yang, Zhiru et al. | 2003
- 8809
-
LIPIDS AND LIPOPROTEINS - Human Group IVC Phospholipase A2 (cPLA2g). ROLES IN THE MEMBRANE REMODELING AND ACTIVATION INDUCED BY OXIDATIVE STRESS.Asai, Kenji et al. | 2003
- 8815
-
MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - Effects of Mutations of ABCA1 in the First Extracellular Domain on Subcellular Trafficking and ATP Binding-Hydrolysis.Tanaka, Arowu R. et al. | 2003
- 8820
-
MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - Protein Domains, Catalytic Activity, and Subcellular Distribution of Neuropathy Target Esterase in Mammalian Cells.Li, Yong et al. | 2003
- 8826
-
GENOMICS, PROTEOMICS, AND BIOINFORMATICS - Highly Coordinated Gene Regulation in Mouse Skeletal Muscle Regeneration.Yan, Zhen et al. | 2003
- 8837
-
MECHANISMS OF SIGNAL TRANSDUCTION - Identification of UNC119 as a Novel Activator of SRC-type Tyrosine Kinases.Cen, Osman et al. | 2003
- 8846
-
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - Overexpression of the Linker Histone-binding Protein tNASP Affects Progression through the Cell Cycle.Alekseev, Oleg M. et al. | 2003
- 8853
-
MEMBRANE TRANSPORT, STRUCTURE, FUNCTION, AND BIOGENESIS - P2X7 Receptor Cell Surface Expression and Cytolytic Pore Formation Are Regulated by a Distal C-terminal Region.Smart, Megan L. et al. | 2003
- 8861
-
DNA: REPLICATION, REPAIR, AND RECOMBINATION - Staphylococcus aureus Gyrase-Quinolone-DNA Ternary Complexes Fail to Arrest Replication Fork Progression tn Vitro. EFFECTS OF SALT ON THE DNA BINDING MODE AND THE CATALYTIC ACTIVITY OF S. AUREUS GYRASE.Hiasa, Hiroshi et al. | 2003