Lead detoxification activities and ADMET hepatotoxicities of a class of novel 5-(1-carbonyl-l-amino-acid)-2,2-dimethyl-[1,3]dithiolane-4-carboxylic acids (Englisch)
- Neue Suche nach: Xu, Yanxia
- Neue Suche nach: Xu, Yanxia
- Neue Suche nach: Wang, Yuji
- Neue Suche nach: Zhao, Ming
- Neue Suche nach: Hou, Baoguang
- Neue Suche nach: Peng, Li
- Neue Suche nach: Zheng, Meiqing
- Neue Suche nach: Wu, Jianhui
- Neue Suche nach: Peng, Shiqi
In:
Bioorganic & medicinal chemistry letters
;
21
, 6
; 1754-1758
;
2011
-
ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:Lead detoxification activities and ADMET hepatotoxicities of a class of novel 5-(1-carbonyl-l-amino-acid)-2,2-dimethyl-[1,3]dithiolane-4-carboxylic acids
-
Beteiligte:Xu, Yanxia ( Autor:in ) / Wang, Yuji / Zhao, Ming / Hou, Baoguang / Peng, Li / Zheng, Meiqing / Wu, Jianhui / Peng, Shiqi
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Erschienen in:Bioorganic & medicinal chemistry letters ; 21, 6 ; 1754-1758
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Verlag:
- Neue Suche nach: Elsevier
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Erscheinungsort:Amsterdam [u.a.]
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Erscheinungsdatum:2011
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ISSN:
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ZDBID:
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Medientyp:Aufsatz (Zeitschrift)
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Format:Print
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Sprache:Englisch
- Neue Suche nach: 35.70 / 44.33 / 44.42
- Weitere Informationen zu Basisklassifikation
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Schlagwörter:
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Klassifikation:
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Datenquelle:
Inhaltsverzeichnis – Band 21, Ausgabe 6
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- 1827
-
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- 1838
-
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- 1844
-
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- 1849
-
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- 1852
-
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- 1857
-
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- 1861
-
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- 1865
-
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- 1865
-
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- 1871
-
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- 1876
-
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- 1880
-
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- 1887
-
Toxic polyketides produced by Fusarium sp., an endophytic fungus isolated from Melia azedarachYang, Sheng-Xiang / Gao, Jin-Ming / Zhang, Qiang / Laatsch, Hartmut et al. | 2010
- 1890
-
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- 1896
-
Synthesis and SAR of sulfoxide substituted carboxyquinolines as NK3 receptor antagonistsXiong, Hui / Kang, James / Woods, James M. / McCauley, John P. Jr. / Koether, Gerard M. / Albert, Jeffrey S. / Hinkley, Lindsay / Li, Yan / Gadient, Reto A. / Simpson, Thomas R. et al. | 2010
- 1900
-
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- 1901
-
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- 1902
-
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