Synthesis and antiprotozoal activity of nitazoxanide–N-methylbenzimidazole hybrids (Englisch)
- Neue Suche nach: Soria-Arteche, Olivia
- Neue Suche nach: Soria-Arteche, Olivia
- Neue Suche nach: Hernández-Campos, Alicia
- Neue Suche nach: Yépez-Mulia, Lilián
- Neue Suche nach: Trejo-Soto, Pedro Josué
- Neue Suche nach: Hernández-Luis, Francisco
- Neue Suche nach: Gres-Molina, Jorge
- Neue Suche nach: Maldonado, Luis A.
- Neue Suche nach: Castillo, Rafael
In:
Bioorganic & medicinal chemistry letters
;
23
, 24
; 6838-6841
;
2013
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ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:Synthesis and antiprotozoal activity of nitazoxanide–N-methylbenzimidazole hybrids
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Beteiligte:
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Erschienen in:Bioorganic & medicinal chemistry letters ; 23, 24 ; 6838-6841
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Verlag:
- Neue Suche nach: Elsevier
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Erscheinungsort:Amsterdam [u.a.]
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Erscheinungsdatum:2013
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ISSN:
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ZDBID:
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Medientyp:Aufsatz (Zeitschrift)
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Format:Print
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Sprache:Englisch
- Neue Suche nach: 35.70 / 44.33 / 44.42
- Weitere Informationen zu Basisklassifikation
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Schlagwörter:
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Datenquelle:
Inhaltsverzeichnis – Band 23, Ausgabe 24
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Comprehending renin inhibitor’s binding affinity using structure-based approachesSubramanian, Govindan / Rao, Shashidhar N. et al. | 2013
- 6673
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Novel glycosylated endomorphin-2 analog produces potent centrally-mediated antinociception in mice after peripheral administrationFichna, Jakub / Mazur, Marzena / Grzywacz, Daria / Kamysz, Wojciech / Perlikowska, Renata / Piekielna, Justyna / Sobczak, Marta / Sałaga, Maciej / Toth, Geza / Janecka, Anna et al. | 2013
- 6677
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The effect of the skeleton structure of flavanone and flavonoid on interaction with transferrinZhang, Xiu-feng / Han, Rui-min / Sun, Xiao-ran / Li, Guang-yue / Yang, Qian-fan / Li, Qian / Gai, Wei / Zhang, Miao / Chen, Lei / Yang, Guang et al. | 2013
- 6682
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Cytotoxic compounds from invasive giant salvinia (Salvinia molesta) against human tumor cellsLi, Shiyou / Wang, Ping / Deng, Guangrui / Yuan, Wei / Su, Zushang et al. | 2013
- 6688
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New cytotoxic benzosuberene analogs. Synthesis, molecular modeling and biological evaluationChen, Zecheng / Maderna, Andreas / Sukuru, Sai Chetan K. / Wagenaar, Melissa / O’Donnell, Christopher J. / Lam, My-Hanh / Musto, Sylvia / Loganzo, Frank et al. | 2013
- 6695
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An assay for human telomeric G-quadruplex DNA binding drugsWatkins, Derrick / Ranjan, Nihar / Kumar, Sunil / Gong, Changjun / Arya, Dev P. et al. | 2013
- 6700
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Radionuclide labeling and evaluation of candidate radioligands for PET imaging of histone deacetylase in the brainSeo, Young Jun / Muench, Lisa / Reid, Alicia / Chen, Jinzhu / Kang, Yeona / Hooker, Jacob M. / Volkow, Nora D. / Fowler, Joanna S. / Kim, Sung Won et al. | 2013
- 6706
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Anion inhibition studies of a @b-carbonic anhydrase from Clostridium perfringensVullo, D. / Sai Kumar, R. S. / Scozzafava, A. / Capasso, C. / Ferry, J. G. / Supuran, C. T. et al. | 2013
- 6706
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Anion inhibition studies of a β-carbonic anhydrase from Clostridium perfringensVullo, Daniela / Sai Kumar, R. Siva / Scozzafava, Andrea / Capasso, Clemente / Ferry, James G. / Supuran, Claudiu T. et al. | 2013
- 6711
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Design and synthesis of novel 3-(benzo[d]oxazol-2-yl)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine derivatives as selective G-protein-coupled receptor kinase-2 and -5 inhibitorsCho, Sung Yun / Lee, Byung Ho / Jung, Heejung / Yun, Chang Soo / Ha, Jae Du / Kim, Hyoung Rae / Chae, Chong Hak / Lee, Jeong Hyun / Seo, Ho Won / Oh, Kwang-Seok et al. | 2013
- 6717
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Truncated and constrained helical analogs of antimicrobial esculentin-2EMPham, Thanh Kim / Kim, Do-Hee / Lee, Bong-Jin / Kim, Young-Woo et al. | 2013
- 6721
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Synthesis and biological evaluation of nimesulide based new class of triazole derivatives as potential PDE4B inhibitors against cancer cellsMareddy, Jyoti / Nallapati, Suresh Babu / Anireddy, Jayasree / Devi, Yumnam Priyadarshini / Mangamoori, Lakshmi Narasu / Kapavarapu, Ravikumar / Pal, Sarbani et al. | 2013
- 6728
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Aza-cycloisodityrosine analogue of RA-VII, an antitumor bicyclic hexapeptideHitotsuyanagi, Yukio / Miyazawa, Akihiro / Hinosawa, Taka-aki / Nakagawa, Yoshie / Hasuda, Tomoyo / Takeya, Koichi et al. | 2013
- 6732
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The ameliorating effects of 2,3-dihydroxy-4-methoxyacetophenone on scopolamine-induced memory impairment in mice and its neuroprotective activityWeon, Jin Bae / Ko, Hyun-Jeong / Ma, Choong Je et al. | 2013
- 6737
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Novel tacrine–ebselen hybrids with improved cholinesterase inhibitory, hydrogen peroxide and peroxynitrite scavenging activityMao, Fei / Chen, Jianwen / Zhou, Qi / Luo, Zonghua / Huang, Ling / Li, Xingshu et al. | 2013
- 6743
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Scorpion toxins for the reversal of BoNT-induced paralysisLowery, Colin A. / Adler, Michael / Borrell, Andrew / Janda, Kim D. et al. | 2013
- 6747
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Discovery of benzo[d]imidazo[5,1-b]thiazole as a new class of phosphodiesterase 10A inhibitorsBanerjee, Abhisek / Narayana, Lakshminarayana / Raje, Firoj A. / Pisal, Dnyandeo V. / Kadam, Pradip A. / Gullapalli, Srinivas / Kumar, Hemant / More, Sandeep V. / Bajpai, Malini / Sangana, Ramachandra Rao et al. | 2013
- 6755
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Synthesis and antitumor activity evaluation of maleopimaric acid N-aryl imide atropisomersYao, Gui-yang / Ye, Man-yi / Huang, Ri-zhen / Li, Ya-jun / Zhu, Yong-tao / Pan, Ying-ming / Liao, Zhi-Xin / Wang, Heng-shan et al. | 2013
- 6759
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Salen and tetrahydrosalen derivatives act as effective inhibitors of the tumor-associated carbonic anhydrase XII—A new scaffold for designing isoform-selective inhibitorsCarradori, Simone / De Monte, Celeste / D’Ascenzio, Melissa / Secci, Daniela / Celik, Gulsah / Ceruso, Mariangela / Vullo, Daniela / Scozzafava, Andrea / Supuran, Claudiu T. et al. | 2013
- 6764
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Synthesis and initial biological evaluation of substituted 1-phenylamino-2-thio-4,5-dimethyl-1H-imidazole derivativesYurttaş, Leyla / Duran, Murat / Demirayak, Şeref / Gençer, Hülya Karaca / Tunalı, Yağmur et al. | 2013
- 6769
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Recycling antimalarial leads for cancer: Antiproliferative properties of N-cinnamoyl chloroquine analoguesPérez, Bianca C. / Fernandes, Iva / Mateus, Nuno / Teixeira, Cátia / Gomes, Paula et al. | 2013
- 6773
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4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable Stearoyl-CoA desaturase-1 (SCD1) inhibitors. Part 1: Urea-based analogsYang, Shyh-Ming / Tang, Yuting / Zhang, Rui / Lu, Huajun / Kuo, Gee-Hong / Gaul, Michael D. / Li, Yaxin / Ho, George / Conway, James G. / Liang, Yin et al. | 2013
- 6777
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The discovery of novel N-(2-pyrimidinylamino) benzamide derivatives as potent hedgehog signaling pathway inhibitorsXin, Minhang / Wen, Jun / Tang, Feng / Tu, Chongxing / Shen, Han / Zhao, Xinge et al. | 2013
- 6784
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Synthesis of novel 7-substituted pyrido[2′,3′:4,5]furo[3,2-d]pyrimidin-4-amines and their N-aryl analogues and evaluation of their inhibitory activity against Ser/Thr kinasesDeau, Emmanuel / Loidreau, Yvonnick / Marchand, Pascal / Nourrisson, Marie-Renée / Loaëc, Nadège / Meijer, Laurent / Levacher, Vincent / Besson, Thierry et al. | 2013
- 6789
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Discovery of a potent respiratory syncytial virus RNA polymerase inhibitorXiong, Hui / Foulk, Melinda / Aschenbrenner, Lisa / Fan, Jun / Tiong-Yip, Choi-Lai / Johnson, Kenneth D. / Moustakas, Demetri / Fleming, Paul R. / Brown, Dean G. / Zhang, Minli et al. | 2013
- 6794
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The chemical synthesis and cytotoxicity of new sulfur analogues of 2-methoxy-lysophosphatidylcholineRytczak, Przemysław / Drzazga, Anna / Gendaszewska-Darmach, Edyta / Okruszek, Andrzej et al. | 2013
- 6799
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Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimicsWiget, Paul A. / Manzano, Lawrence A. / Pruet, Jeff M. / Gao, Grace / Saito, Ryota / Monzingo, Arthur F. / Jasheway, Karl R. / Robertus, Jon D. / Anslyn, Eric V. et al. | 2013
- 6805
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Design, synthesis and evaluation of 6-(4-((substituted-1H-1,2,3-triazol-4-yl)methyl)piperazin-1-yl)phenanthridine analogues as antimycobacterial agentsNagesh, Hunsur Nagendra / Naidu, Kalaga Mahalakshmi / Rao, Damarla Harika / Sridevi, Jonnalagadda Padma / Sriram, Dharmarajan / Yogeeswari, Perumal / Chandra Sekhar, Kondapalli Venkata Gowri et al. | 2013
- 6811
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A ratiometric fluorescent detection of Zn(II) in aqueous solutions using pyrene-appended histidineThirupathi, Ponnaboina / Lee, Keun-Hyeung et al. | 2013
- 6816
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Amino acids derived benzoxazepines: Design, synthesis and antitumor activityDwivedi, Shailendra Kumar Dhar / Samanta, Krishnananda / Yadav, Manisha / Jana, Amit Kumar / Singh, Abhishek Kumar / Chakravarti, Bandana / Mondal, Sankalan / Konwar, Rituraj / Trivedi, Arun Kumar / Chattopadhyay, Naibedya et al. | 2013
- 6822
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Assembly of pyrene-modified DNA/RNA duplexes incorporating a G-rich single strand regionSeio, Kohji / Tokugawa, Munefumi / Tsunoda, Hirosuke / Ohkubo, Akihiro / Arisaka, Fumio / Sekine, Mitsuo et al. | 2013
- 6825
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Potent P2Y1 urea antagonists bearing various cyclic amine scaffoldsRuel, Réjean / L’Heureux, Alexandre / Thibeault, Carl / Lapointe, Philippe / Martel, Alain / Qiao, Jennifer X. / Hua, Ji / Price, Laura A. / Wu, Qimin / Chang, Ming et al. | 2013
- 6829
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Novel Mps1 kinase inhibitors: From purine to pyrrolopyrimidine and quinazoline leadsBursavich, Matthew G. / Dastrup, David / Shenderovich, Mark / Yager, Kraig M. / Cimbora, Daniel M. / Williams, Brandi / Kumar, D. Vijay et al. | 2013
- 6834
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Design, synthesis and cytotoxicity of novel 3′-N-alkoxycarbonyl docetaxel analogsChang, Jun / Hao, Xiao-Dong / Hao, Yun-Peng / Lu, Hong-Fu / Yu, Jian-Ming / Sun, Xun et al. | 2013
- 6838
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Synthesis and antiprotozoal activity of nitazoxanide–N-methylbenzimidazole hybridsSoria-Arteche, Olivia / Hernández-Campos, Alicia / Yépez-Mulia, Lilián / Trejo-Soto, Pedro Josué / Hernández-Luis, Francisco / Gres-Molina, Jorge / Maldonado, Luis A. / Castillo, Rafael et al. | 2013
- 6842
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Anti-tubercular agents. Part 8: Synthesis, antibacterial and antitubercular activity of 5-nitrofuran based 1,2,3-triazolesKamal, Ahmed / Hussaini, Syed Mohammed Ali / Faazil, Shaikh / Poornachandra, Y. / Narender Reddy, G. / Kumar, C. Ganesh / Rajput, Vikrant Singh / Rani, Chitra / Sharma, Rashmi / Khan, Inshad Ali et al. | 2013
- 6847
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Synthesis of 2′-O-(thymin-1-yl)methyluridine and its incorporation into secondary nucleic acid structuresKumar, Pawan / Madsen, Charlotte S. / Nielsen, Poul et al. | 2013
- 6851
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Polycation-assisted DNA detection by reduction triggered fluorescence amplification probeSaneyoshi, Hisao / Shimada, Naohiko / Maruyama, Atsushi / Ito, Yoshihiro / Abe, Hiroshi et al. | 2013
- 6854
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Synthesis, DNA-binding abilities and anticancer activities of triazole-pyrrolo[2,1-c][1,4]benzodiazepines hybrid scaffoldsChen, Chung-Yu / Lee, Pei-Hua / Lin, Yong-Yong / Yu, Wen-Ting / Hu, Wan-Ping / Hsu, Chia-Chen / Lin, Ying-Ting / Chang, Long-Sen / Hsiao, Cheng-Tien / Wang, Jeh-Jeng et al. | 2013
- 6860
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Cytidine derivatives as IspF inhibitors of Burkolderia pseudomalleiZhang, Zheng / Jakkaraju, Sriram / Blain, Joy / Gogol, Kenneth / Zhao, Lei / Hartley, Robert C. / Karlsson, Courtney A. / Staker, Bart L. / Edwards, Thomas E. / Stewart, Lance J. et al. | 2013
- 6864
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Antiproliferative activities and SAR studies of substituted anthraquinones and 1,4-naphthoquinonesBhasin, Deepak / Etter, Jonathan P. / Chettiar, Somsundaram N. / Mok, May / Li, Pui-Kai et al. | 2013
- 6868
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3′,4′-Bis-difluoromethoxycinnamoylanthranilate (FT061): An orally-active antifibrotic agent that reduces albuminuria in a rat model of progressive diabetic nephropathyWilliams, Spencer J. / Zammit, Steven C. / Cox, Alison J. / Shackleford, David M. / Morizzi, Julia / Zhang, Yuan / Powell, Andrew K. / Gilbert, Richard E. / Krum, Henry / Kelly, Darren J. et al. | 2013
- 6874
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Design, synthesis, and evaluation of curcumin-derived arylheptanoids for glioblastoma and neuroblastoma cytotoxicityCampos, Catherine A. / Gianino, Joseph B. / Bailey, Barbara J. / Baluyut, Mary E. / Wiek, Constanze / Hanenberg, Helmut / Shannon, Harlan E. / Pollok, Karen E. / Ashfeld, Brandon L. et al. | 2013
- 6879
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Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors with sub-micromolar potency in the cell-based replicon assayStammers, Timothy A. / Coulombe, René / Duplessis, Martin / Fazal, Gulrez / Gagnon, Alexandre / Garneau, Michel / Goulet, Sylvie / Jakalian, Araz / LaPlante, Steven / Rancourt, Jean et al. | 2013
- 6886
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Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamidesKothayer, Hend / Elshanawani, Abdalla A. / Abu Kull, Mansour E. / El-Sabbagh, Osama I. / Shekhar, Malathy P.V. / Brancale, Andrea / Jones, Arwyn T. / Westwell, Andrew D. et al. | 2013
- 6890
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Identification of clinical candidates from the benzazepine class of histamine H3 receptor antagonistsWilson, David M. / Apps, James / Bailey, Nicholas / Bamford, Mark J. / Beresford, Isabel J. / Brackenborough, Kim / Briggs, Michael A. / Brough, Stephen / Calver, Andrew R. / Crook, Barry et al. | 2013
- 6897
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The discovery of the benzazepine class of histamine H3 receptor antagonistsWilson, David M. / Apps, James / Bailey, Nicholas / Bamford, Mark J. / Beresford, Isabel J. / Briggs, Michael A. / Calver, Andrew R. / Crook, Barry / Davis, Robert P. / Davis, Susannah et al. | 2013
- 6902
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Structure–activity relationship studies of thalidomide analogs with a taxol-like mode of actionPandit, Bulbul / Hu, Zhigen / Chettiar, Somsundaram N. / Zink, Jennifer / Xiao, Zili / Etter, Jonathan P. / Bhasin, Deepak / Li, Pui-Kai et al. | 2013
- 6905
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(S)-4-Trimethylsilyl-3-butyn-2-ol as an auxiliary for stereocontrolled synthesis of salinosporamide analogs with modifications at positions C2 and C5Blasdel, Landy K. / Lee, DongEun / Sun, Binyuan / Myers, Andrew G. et al. | 2013
- 6911
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Synthetic @a-(aminomethyl)-@c-butyrolactones and their anti-pancreatic cancer activitiesRamachandran, P. V. / Nicponski, D. R. / Nair, H. N. G. / Helppi, M. A. / Gagare, P. D. / Schmidt, C. M. / Yip-Schneider, M. T. et al. | 2013
- 6911
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Synthetic α-(aminomethyl)-γ-butyrolactones and their anti-pancreatic cancer activitiesRamachandran, P. Veeraraghavan / Nicponski, Daniel R. / Nair, Hari N.G. / Helppi, Matthew A. / Gagare, Pravin D. / Schmidt, C. Max / Yip-Schneider, Michele T. et al. | 2013
- 6915
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Asymmetric synthesis and effect of absolute stereochemistry of YCZ-2013, a brassinosteroid biosynthesis inhibitorOh, Keimei / Yamada, Kazuhiro / Yoshizawa, Yuko et al. | 2013
- 6920
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Chlorophenylpiperazine analogues as high affinity dopamine transporter ligandsMotel, William C. / Healy, Jason R. / Viard, Eddy / Pouw, Buddy / Martin, Kelly E. / Matsumoto, Rae R. / Coop, Andrew et al. | 2013
- 6923
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Oxime-based inhibitors of glucose transporter 1 displaying antiproliferative effects in cancer cellsTuccinardi, Tiziano / Granchi, Carlotta / Iegre, Jessica / Paterni, Ilaria / Bertini, Simone / Macchia, Marco / Martinelli, Adriano / Qian, Yanrong / Chen, Xiaozhuo / Minutolo, Filippo et al. | 2013
- 6928
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6-(4-Pyridyl)pyrimidin-4(3H)-ones as CNS penetrant glycogen synthase kinase-3@b inhibitorsUehara, F. / Shoda, A. / Aritomo, K. / Fukunaga, K. / Watanabe, K. / Ando, R. / Shinoda, M. / Ueno, H. / Kubodera, H. / Sunada, S. et al. | 2013
- 6928
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6-(4-Pyridyl)pyrimidin-4(3H)-ones as CNS penetrant glycogen synthase kinase-3β inhibitorsUehara, Fumiaki / Shoda, Aya / Aritomo, Keiichi / Fukunaga, Kenji / Watanabe, Kazutoshi / Ando, Ryoichi / Shinoda, Masaki / Ueno, Hiroaki / Kubodera, Hideo / Sunada, Shinji et al. | 2013
- 6933
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2-(2-Phenylmorpholin-4-yl)pyrimidin-4(3H)-ones; A new class of potent, selective and orally active glycogen synthase kinase-3@b inhibitorsFukunaga, K. / Uehara, F. / Aritomo, K. / Shoda, A. / Hiki, S. / Okuyama, M. / Usui, Y. / Watanabe, K. / Yamakoshi, K. / Kohara, T. et al. | 2013
- 6933
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2-(2-Phenylmorpholin-4-yl)pyrimidin-4(3H)-ones; A new class of potent, selective and orally active glycogen synthase kinase-3β inhibitorsFukunaga, Kenji / Uehara, Fumiaki / Aritomo, Keiichi / Shoda, Aya / Hiki, Shinsuke / Okuyama, Masahiro / Usui, Yoshihiro / Watanabe, Kazutoshi / Yamakoshi, Koichi / Kohara, Toshiyuki et al. | 2013
- 6938
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Corrigendum to “Potent antimalarial 4-pyridones with improved physico-chemical properties” [Bioorg. Med. Chem. Lett. 21 (2011) 5214–5218]Bueno, José M. / Manzano, Pilar / García, María C. / Chicharro, Jesús / Puente, Margarita / Lorenzo, Milagros / García, Adolfo / Ferrer, Santiago / Gómez, Rubén M. / Fraile, María T. et al. | 2013
- 6939
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Corrigendum to “Development of an in vivo active, dual EP1 and EP3 selective antagonist based on a novel acyl sulfonamide bioisostere” [Bioorg. Med. Chem. Lett. 23 (2013) 37–41]Downey, Jason D. / Saleh, Sam A. / Bridges, Thomas M. / Morrison, Ryan D. / Daniels, J. Scott / Lindsley, Craig W. / Breyer, Richard M. et al. | 2013
- IFC
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Editorial board| 2013